Title:
METHOD FOR PREPARING ORGANIC ACID BY BATCH-FEEDING CARBON SOURCE SUBSTRATE AND BASE
Document Type and Number:
WIPO Patent Application WO/2013/176460
Kind Code:
A1
Abstract:
The present invention provides a fed-batch culture method comprising a step of batch-feeding a carbon source base and a base in such a manner that the pH level can be maintained at a level suitable for the growth of microorganisms for fermentation of a carbon source. The present invention also provides a method for preparing organic acids using the fed-batch culture method. The present invention batch-feeds a neutralizing agent such as ammonium bicarbonate, ammonium carbonate or alkali metal-containing weak base, and a carbon source substrate in preparing organic acids by microorganism fermentation. Thus, a pH level suitable for the survival of microorganisms for carbon source fermentation can be maintained, and the speed of injecting the carbon source base which is the source material can be appropriately adjusted. The present invention may improve productivity, yield rate and concentration of organic acids and may automatically inject a base and a carbon source substrate according to a variation in the pH level, thus improving reliability and convenience of a fermentation process operation.
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Inventors:
PARK JAE YEON (KR)
KANG SIN YOUNG (KR)
PARK WOO CHAN (KR)
KOO MIN SU (KR)
CHO IN HO (KR)
PARK JOONG MIN (KR)
LEE SEUNG YEOP (KR)
KIM DONG HYUN (KR)
KANG SIN YOUNG (KR)
PARK WOO CHAN (KR)
KOO MIN SU (KR)
CHO IN HO (KR)
PARK JOONG MIN (KR)
LEE SEUNG YEOP (KR)
KIM DONG HYUN (KR)
Application Number:
PCT/KR2013/004439
Publication Date:
November 28, 2013
Filing Date:
May 21, 2013
Export Citation:
Assignee:
SK INNOVATION CO LTD (KR)
SK ENERGY CO LTD (KR)
SK ENERGY CO LTD (KR)
International Classes:
C12P7/40; C12N1/20; C12P7/52
Foreign References:
| US20110177567A1 | 2011-07-21 | |||
| KR20120025998A | 2012-03-16 | |||
| US20060014260A1 | 2006-01-19 |
Other References:
LIU, JUAN-BIN ET AL.: "Process of rice straw degradation and dynamic trend of pH by the microbial community MC1", JOURNAL OF ENVIRONMENTAL SCIENCES, vol. 18, no. 6, 2006, pages 1142 - 1146
OHKOUCHI, Y ET AL.: "Direct production of 1(+)-lactic acid from starch and food wastes using Lactobacillus manihotivorans LMG18011", BIORESOURCE TECHNOLOGY, vol. 97, no. 13, September 2006 (2006-09-01), pages 1554 - 1562
OHKOUCHI, Y ET AL.: "Direct production of 1(+)-lactic acid from starch and food wastes using Lactobacillus manihotivorans LMG18011", BIORESOURCE TECHNOLOGY, vol. 97, no. 13, September 2006 (2006-09-01), pages 1554 - 1562
Attorney, Agent or Firm:
LEE & PARK (KR)
청운특허법인 (KR)
청운특허법인 (KR)
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