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Title:
METHOD FOR PREPARING SUBSTITUTED PHENYLACETIC ACID DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2016/206373
Kind Code:
A1
Abstract:
The present invention belongs to the field of pharmaceutical synthesis, relates to a method for preparing a substituted phenylacetic acid derivative, and particularly, to a method for preparing 2-[4-(2-oxopent methyl)phenylpropionic acid], as shown in formula I-1. The preparation method is not guided by the prior art, and cannot acquire technical inspiration from the prior art. The preparation method uses cheap raw materials, and is applicable to commercial scale production.

Inventors:
ZHU, Guoliang (99 Waisha Road, Jiaojiang DistrictTaizhou, Zhejiang 0, 318000, CN)
MA, Du (99 Waisha Road, Jiaojiang DistrictTaizhou, Zhejiang 0, 318000, CN)
CHEN, Chalin (99 Waisha Road, Jiaojiang DistrictTaizhou, Zhejiang 0, 318000, CN)
CHEN, Shijian (99 Waisha Road, Jiaojiang DistrictTaizhou, Zhejiang 0, 318000, CN)
Application Number:
CN2016/071427
Publication Date:
December 29, 2016
Filing Date:
January 20, 2016
Export Citation:
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Assignee:
ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (LIU Li, 99 Waisha Road Jiaojiang Distric, Taizhou Zhejiang 0, 318000, CN)
International Classes:
C07C51/36; C07C51/41; C07C67/303; C07C59/86; C07C69/738
Foreign References:
GB2002762A1979-02-28
US4407823A1983-10-04
Other References:
LIU, XU ET AL.: "SpinPhox/Iridium (I) -Catalyzed Asymmetric Hydrogenation of Cyclic a-Alkylidene Carbonyl Compounds", ANGEWANDTE CHEMIE , INTERNATIONAL EDITION, vol. 53, no. 7, 31 December 2014 (2014-12-31), pages 1981
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