METHOD OF PREPARING WELL-DEFINED POLYPEPTIDES VIA ROP

Title:

METHOD OF PREPARING WELL-DEFINED POLYPEPTIDES VIA ROP

Document Type and Number:

WIPO Patent Application WO/2015/140649

Kind Code:

A3

Abstract:

A process for living ring-opening polymerization can include exposing an N- carboxyanhydride monomer to an initiator that includes a first primary amine covalently linked to a first electron donor by a first linking group to form a polyamide polymer. The initiator can include a second primary amine, optionally a second electron donor, and optionally a third electron donor.

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Inventors:

HADJICHRISTIDIS NIKOLAOS (SA)
ZHAO WEI (SA)
GNANOU YVES (SA)

Application Number:

PCT/IB2015/001146

Publication Date:

December 17, 2015

Filing Date:

March 17, 2015

Export Citation:

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Assignee:

UNIV KING ABDULLAH SCI & TECH (SA)

International Classes:

C08G69/10

Domestic Patent References:

WO2009058291A2

2009-05-07

Other References:

DEMING T J: "Polypeptide and polypeptide hybrid copolymer synthesis via NCA polymerization", 23 February 2006, PEPTIDE HYBRID POLYMERS, SPRINGER-VERLAG BERLIN HEIDELBERG, BERLIN HEIDELBERG, PAGE(S) 1 - 18, ISBN: 978-3-540-32567-3, XP008173852

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