METHOD FOR PREVENTING ACUTE RENAL FAILURE - CRITICAL THERAPEUTICS INC

Title:

METHOD FOR PREVENTING ACUTE RENAL FAILURE

Document Type and Number:

WIPO Patent Application WO2002081020

Kind Code:

A3

Abstract:

Disclosed is a method of treating acute renal failure in a subject. The method comprises the step of administering to the subject an effective amount of a composition comprising a 2-ketoalkanoic acid, a pharmaceutically acceptable salt of a 2-ketoalkanoic acid, an ester of a 2-ketoalkanoic acid, or an amide of a 2-ketoalkanoic acid. Preferably, the composition comprises an enolization agent and an alkyl aralkyl, alkoxyalkyl or carboxyalkyl ester of a 2-ketoalkanoic acid dissolved in a pharmaceutically acceptable vehicle.

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Inventors:

FINK MITCHELL P (US)
WARREN H SHAW (US)

Application Number:

PCT/US2002/010539

Publication Date:

January 09, 2003

Filing Date:

April 03, 2002

Export Citation:

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Assignee:

CRITICAL THERAPEUTICS INC (US)
FINK MITCHELL P (US)
WARREN H SHAW (US)

International Classes:

A61K31/16; A61K31/19; A61P13/12; A61K31/22; (IPC1-7): A61K31/16; A61K19/22

Foreign References:

US4228099A	1980-10-14
US4752619A	1988-06-21
US4908214A	1990-03-13
US4957938A	1990-09-18
US5210098A	1993-05-11

Other References: