Title:
METHOD FOR PREVENTING AND TREATING LIPID-INDUCED RENAL INJURY
Document Type and Number:
WIPO Patent Application WO/2018/107689
Kind Code:
A1
Abstract:
Provided is a method for preventing and/or treating lipid-induced renal injury and related diseases thereof of a subject, comprising administering a preventively and/or therapeutically effective amount of plasminogen to a subject prone to suffer or suffering lipid metabolism disorders, or suffering other diseases accompanied by lipid metabolism disorders. The present invention also relates to a medicine, pharmaceutical composition, product, and kit comprising plasminogen and used for preventing and/or treating lipid-induced renal injury and related diseases thereof of a subject.
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Inventors:
LI JINAN (CN)
Application Number:
PCT/CN2017/089048
Publication Date:
June 21, 2018
Filing Date:
June 19, 2017
Export Citation:
Assignee:
TALENGEN INST LIFE SCIENCES CO LTD (CN)
International Classes:
A61K38/43; A61P3/04
Domestic Patent References:
| WO2008027000A2 | 2008-03-06 | |||
| WO2010083570A1 | 2010-07-29 |
Foreign References:
| CN101132788A | 2008-02-27 | |||
| CN102121023A | 2011-07-13 |
Other References:
DATABASE Protein 19 March 1999 (1999-03-19), FORSGREN, M.: "plasminogen [Homo sapiens", XP055605930, retrieved from NCBI Database accession no. NP_000292.1
CHEN ET AL: "Effects of Fibrate on the Pathophysiology of Kidney", INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM, vol. 29, no. 5, 30 September 2009 (2009-09-30), pages 332 - 334
WU ET AL: "The Research Progress of Relationship between Lipid Regulation and Diabetic Nephropathy", MEDICINE AND PHILOSOPHY, vol. 557, no. 9B, 23 September 2016 (2016-09-23), pages 66 - 69
ALESSI, M.C.: "PAI-1 and the metabolic syndrome: links, causes, and consequences", ARTERIOSCLER THROMB VASC BIOL., vol. 26, no. 10, 24 August 2006 (2006-08-24), pages 2200 - 2207, XP055509617, DOI: doi:10.1161/01.ATV.0000242905.41404.68
CHEN ET AL: "Effects of Fibrate on the Pathophysiology of Kidney", INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM, vol. 29, no. 5, 30 September 2009 (2009-09-30), pages 332 - 334
WU ET AL: "The Research Progress of Relationship between Lipid Regulation and Diabetic Nephropathy", MEDICINE AND PHILOSOPHY, vol. 557, no. 9B, 23 September 2016 (2016-09-23), pages 66 - 69
ALESSI, M.C.: "PAI-1 and the metabolic syndrome: links, causes, and consequences", ARTERIOSCLER THROMB VASC BIOL., vol. 26, no. 10, 24 August 2006 (2006-08-24), pages 2200 - 2207, XP055509617, DOI: doi:10.1161/01.ATV.0000242905.41404.68
Attorney, Agent or Firm:
BEIJING CAI HE LAW FIRM (CN)
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