Title:
METHOD FOR PREVENTING AND TREATING TISSUE INJURY CAUSED BY ABNORMAL DEPOSITION OF LIPID
Document Type and Number:
WIPO Patent Application WO/2018/107691
Kind Code:
A1
Abstract:
Provided is a method for preventing and/or reducing the abnormal deposition of lipid in tissues and organs of the body of a subject, comprising administering an effective amount of plasminogen to a subject. Also provided are a medicine, pharmaceutical composition, product, and kit comprising plasminogen and used for preventing and/or reducing the abnormal deposition of lipid in tissues and organs of the body of a subject.
Inventors:
LI JINAN (CN)
Application Number:
PCT/CN2017/089051
Publication Date:
June 21, 2018
Filing Date:
June 19, 2017
Export Citation:
Assignee:
TALENGEN INST LIFE SCIENCES CO LTD (CN)
International Classes:
A61K38/48; A61P3/04
Domestic Patent References:
| WO2010076655A1 | 2010-07-08 |
Foreign References:
| CN102378753A | 2012-03-14 | |||
| CN105008323A | 2015-10-28 | |||
| CN1768138A | 2006-05-03 | |||
| CN102532326A | 2012-07-04 | |||
| CN102123721A | 2011-07-13 |
Other References:
CRANDALL, D. L.: "Modulation of Adipose Tissue Development by Pharmacologi- cal Inhibition of PAI-1", ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY, vol. 26, no. 10, 31 October 2006 (2006-10-31), pages 2209 - 2015, XP055605885
BEIER, J. ET AL: "Alcoholic liver disease and the potential role of plasminogen activator inhibitor-1 and fibrin metabolism", EXPERIMENTAL BIOLOGY AND MEDICINE, vol. 237, no. 1, 31 January 2012 (2012-01-31), pages 1 - 9, XP055510382
SKURK, T: "Obesity and impaired fibrinolysis: role of adipose production of plasminogen activator inhibitor-1", INTERNATIONAL JOURNAL OF OBESITY, vol. 28, no. 11, 31 August 2004 (2004-08-31), pages 1357 - 1364, XP055605890
BEIER, J. ET AL: "Alcoholic liver disease and the potential role of plasminogen activator inhibitor-1 and fibrin metabolism", EXPERIMENTAL BIOLOGY AND MEDICINE, vol. 237, no. 1, 31 January 2012 (2012-01-31), pages 1 - 9, XP055510382
SKURK, T: "Obesity and impaired fibrinolysis: role of adipose production of plasminogen activator inhibitor-1", INTERNATIONAL JOURNAL OF OBESITY, vol. 28, no. 11, 31 August 2004 (2004-08-31), pages 1357 - 1364, XP055605890
Attorney, Agent or Firm:
BEIJING CAI HE LAW FIRM (CN)
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