Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHOD FOR PRODUCING 1,3-PROPANEDIOL USING MICROORGANISM VARIANT WITH DELETION OF 2,3-BUTANEDIOL SYNTHETIC GENE
Document Type and Number:
WIPO Patent Application WO/2015/126112
Kind Code:
A1
Abstract:
The present invention relates to a method for producing 1,3-propanediol using a microorganism variant with a deletion of a 2,3-butanediol synthetic gene and, more specifically, to a variant microorganism wherein, in a microorganism having an ability to produce 1,3-propanediol from glycerol, a gene coding lactate dehydrogenase and a gene of an enzyme involved in the synthesis of 2,3-butanediol are deleted, and a gene coding pyruvate decarboxylase and a gene coding aldehyde dehydrogenase are inserted or amplified; and to a method for promoting the production of 1,3-propanediol by using the variant microorganism. The use of a glycerol fermentation microorganism variant according to the present invention can remarkably increase the production of 1,3-propanediol while maximally suppressing the production of 2,3-butanediol.

Inventors:
KIM CHUL HO (KR)
SEO JEONG-WOO (KR)
HEO SUN-YEON (KR)
LEE SUNG MOK (KR)
PARK JANG MIN (KR)
OH BAEK ROCK (KR)
JUNG YOU REE (KR)
Application Number:
PCT/KR2015/001533
Publication Date:
August 27, 2015
Filing Date:
February 16, 2015
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KOREA RES INST OF BIOSCIENCE (KR)
International Classes:
C12N1/21; C12N15/52; C12P7/16; C12R1/22
Foreign References:
KR20130025701A2013-03-12
EP2407544A12012-01-18
KR100509310B12005-08-22
Other References:
BAEK-ROCK OH, APPL BIOCHEM BIOTECHNOL, vol. 166, 2012, pages 127 - 137, XP019998977
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
이처영 (KR)
Download PDF: