Title:
METHOD FOR PRODUCING AMINOGLYCOSIDE ANTIBIOTIC
Document Type and Number:
WIPO Patent Application WO/2017/078098
Kind Code:
A1
Abstract:
Provided is a method for stably producing (2S)-2-hydroxydibekacin, said method being characterized by the use of 2-hydroxykanamycin C or 2-hydroxykanamycin B as a starting material or synthetic intermediate.
Inventors:
TAKAHASHI YOSHIAKI (JP)
AKIYAMA YOSHIHISA (JP)
TSUSHIMA MASAKI (JP)
KIKUCHI CHIKA (JP)
IMAI TAKAHIRO (JP)
TAKAHASHI MASAAKI (JP)
AKIYAMA YOSHIHISA (JP)
TSUSHIMA MASAKI (JP)
KIKUCHI CHIKA (JP)
IMAI TAKAHIRO (JP)
TAKAHASHI MASAAKI (JP)
Application Number:
PCT/JP2016/082668
Publication Date:
May 11, 2017
Filing Date:
November 02, 2016
Export Citation:
Assignee:
MEIJI SEIKA PHARMA CO LTD (JP)
MICROBIAL CHEM RES FOUND (JP)
MICROBIAL CHEM RES FOUND (JP)
International Classes:
C07H15/234; A61K31/7036; A61P31/04
Domestic Patent References:
WO2007142150A1 | 2007-12-13 | |||
WO2009069800A1 | 2009-06-04 |
Foreign References:
JPS608299A | 1985-01-17 | |||
CN101575354A | 2009-11-11 |
Other References:
YONETA,T. ET AL.: "An improved synthesis of 3', 4'-dideoxykanamycin B", BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 52, no. 4, 1979, pages 1131 - 1134, XP055379556
RAKHIT,S. ET AL.: "Facile synthesis of purpurosamine C, a component of the antibiotic gentamicin Cla", JOURNAL OF CARBOHYDRATES, NUCLEOSIDES, NUCLEOTIDES, vol. 2, no. 2, 1975, pages 153 - 157
RAKHIT,S. ET AL.: "Facile synthesis of purpurosamine C, a component of the antibiotic gentamicin Cla", JOURNAL OF CARBOHYDRATES, NUCLEOSIDES, NUCLEOTIDES, vol. 2, no. 2, 1975, pages 153 - 157
Attorney, Agent or Firm:
NAGAI Hiroshi et al. (JP)
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