Title:
METHOD FOR PRODUCING ANGIOGENESIS-INDUCING CELL POPULATION
Document Type and Number:
WIPO Patent Application WO/2024/071223
Kind Code:
A1
Abstract:
The present invention provides a method for producing an angiogenesis-inducing cell population. This method comprises: (1) a step for coculturing a cell population derived from bone marrow fluid or blood with OP9 cells; or (2) a step for culturing a cell population derived from bone marrow fluid or blood in an OP9 cell culture supernatant.
Inventors:
YAMAHARA KENICHI (JP)
MATSUYAMA TOMOHIRO (JP)
SOMA TOSHIHIRO (JP)
YOSHIMURA SHINICHI (JP)
NAKAGOMI TAKAYUKI (JP)
TAKAGI TOSHINORI (JP)
MATSUYAMA TOMOHIRO (JP)
SOMA TOSHIHIRO (JP)
YOSHIMURA SHINICHI (JP)
NAKAGOMI TAKAYUKI (JP)
TAKAGI TOSHINORI (JP)
Application Number:
PCT/JP2023/035205
Publication Date:
April 04, 2024
Filing Date:
September 27, 2023
Export Citation:
Assignee:
HYOGO MEDICAL UNIV (JP)
CTEX CO LTD
CTEX CO LTD
International Classes:
C12N5/078; A61K35/15; A61P9/10; C12N5/0786
Domestic Patent References:
| WO2014051154A1 | 2014-04-03 | |||
| WO2005026343A1 | 2005-03-24 |
Other References:
YASUNORI YOSHIDA: "Enhanced angiogenic properties of umbilical cord blood primed by OP9 stromal cells ameliorates neurological deficits in cerebral infarction mouse model", SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, US, vol. 13, no. 1, 1 January 2023 (2023-01-01), US , XP093154153, ISSN: 2045-2322, DOI: 10.1038/s41598-023-27424-7
YAMAHARA, KENICHI: "Establishment of hematopoietic cells to induce angiogenesis using OP9 feeder cell", PROCEEDINGS OF THE 22TH CONGRESS OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE, 3 March 2023 (2023-03-03), pages 46
YAMAHARA, KENICHI ET AL.: "Examination of changes in angiogenic properties of umbilical cord blood by OP9 co-culture and therapeutic effects by transplantation into a cerebral infarction model", PROCEEDINGS OF THE 22TH CONGRESS OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE, O-10-1, 3 March 2023 (2023-03-03), pages 53
YAMAHARA, KENICHI: "Establishment of hematopoietic cells to induce angiogenesis using OP9 feeder cell", PROCEEDINGS OF THE 22TH CONGRESS OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE, 3 March 2023 (2023-03-03), pages 46
YAMAHARA, KENICHI ET AL.: "Examination of changes in angiogenic properties of umbilical cord blood by OP9 co-culture and therapeutic effects by transplantation into a cerebral infarction model", PROCEEDINGS OF THE 22TH CONGRESS OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE, O-10-1, 3 March 2023 (2023-03-03), pages 53
Attorney, Agent or Firm:
KAMADA, Mitsunori et al. (JP)
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