Title:
METHOD FOR PRODUCING AZIDE COMPOUND, AND METHOD FOR PRODUCING 1H-TETRAZOLE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2013/187325
Kind Code:
A1
Abstract:
The present invention provides a method for producing an azide compound. The method is characterized by producing an azide compound in the form of a solution, the azide compound being represented by general formula (I) (wherein, Y represents an alkyl group, an aryl alkyl group, a silyl group having a substituent, or a silyl alkyl group having a substituent) and being produced by reacting an alkylation agent or a sylilation agent with an azide represented by general formula (II) (wherein, M represents an alkali metal atom or an alkali earth metal atom, and m represents the number one or two) within a flow reactor. M(N3)m…(Ⅱ) Y—N3…(Ⅰ)
Inventors:
MIYAZAKI HIDEKAZU (JP)
Application Number:
PCT/JP2013/065833
Publication Date:
December 19, 2013
Filing Date:
June 07, 2013
Export Citation:
Assignee:
NIPPON SODA CO (JP)
International Classes:
C07C247/04; C07D257/04
Domestic Patent References:
| WO2010103783A1 | 2010-09-16 | |||
| WO2011110651A1 | 2011-09-15 | |||
| WO2003016303A1 | 2003-02-27 | |||
| WO2010103783A1 | 2010-09-16 | |||
| WO2011110651A1 | 2011-09-15 |
Other References:
GUTMANN, B. ET AL.: "Synthesis of 5-Substituted 1H-Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High-Temperature Microreactor Approach", ANGEW. CHEM. INT. ED., vol. 49, 2010, pages 7101 - 7105, XP055176761
PALDE, P. B. ET AL.: "Safe and Efficient Tetrazole Synthesis in a Continuous-Flow Microreactor", ANGEW. CHEM. INT. ED., vol. 50, 2011, pages 3525 - 3528, XP055009296
SHIN'ICHIRO FUSE: "Organic Synthesis Using Microflow Reactor", JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY 0037-9980, vol. 70, no. 2, February 2012 (2012-02-01), JAPAN, pages 177 - 178, XP008175525
See also references of EP 2860173A4
DIMROTH, O. AND WISLICENUS, W., CHEMISCHE BERICHTE, vol. 38, 1905, pages 1573
GUTMANN ET AL., ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 49, no. 39, 2010, pages 7101 - 7105
PALDE, P. B. ET AL.: "Safe and Efficient Tetrazole Synthesis in a Continuous-Flow Microreactor", ANGEW. CHEM. INT. ED., vol. 50, 2011, pages 3525 - 3528, XP055009296
SHIN'ICHIRO FUSE: "Organic Synthesis Using Microflow Reactor", JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY 0037-9980, vol. 70, no. 2, February 2012 (2012-02-01), JAPAN, pages 177 - 178, XP008175525
See also references of EP 2860173A4
DIMROTH, O. AND WISLICENUS, W., CHEMISCHE BERICHTE, vol. 38, 1905, pages 1573
GUTMANN ET AL., ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 49, no. 39, 2010, pages 7101 - 7105
Attorney, Agent or Firm:
SHIGA Masatake et al. (JP)
Masatake Shiga (JP)
Masatake Shiga (JP)
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