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Title:
METHOD FOR PRODUCING BICYCLIC G-AMINO ACID DERIVATIVE
Document Type and Number:
WIPO Patent Application WO2010110361
Kind Code:
A1
Abstract:
Disclosed is a method for producing a compound which has an excellent activity as an a2d ligand. Specifically disclosed is a method for producing a compound represented by general formula (I) or a salt thereof through optical resolution. In formula (I), R1 represents a hydrogen atom or a C1-6 alkyl group; and R2 represents a hydrogen atom or a carboxy-protecting group.

Inventors:
KITAGAWA YUTAKA
IMAI MAKOTO
Application Number:
JP2010055202W
Publication Date:
September 30, 2010
Filing Date:
March 25, 2010
Export Citation:
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Assignee:
DAIICHI SANKYO COMPANY,LIMITED
KITAGAWA, YUTAKA
IMAI, MAKOTO
International Classes:
C07C227/34; A61K31/195; A61K31/215; A61P25/04; A61P43/00; C07C229/32; C07B57/00; C12N15/09
Domestic Patent References:
WO2009041453A12009-04-02
WO2004006836A22004-01-22
WO1999021824A11999-05-06
WO2001028978A12001-04-26
WO2002085839A12002-10-31
Foreign References:
JP2006501297A2006-01-12
Other References:
TETRAHEDRON: ASYMMETRY, vol. 13, 2002, pages 625 - 632, XP004352553
See also references of EP 2412700A4
J BIOL. CHEM., vol. 271, no. 10, 1996, pages 5768 - 5776
J MED. CHEM., vol. 41, 1998, pages 1838 - 18445
ACTA NEUROL. SCAND., vol. 101, 2000, pages 359 - 371
DRUGS, vol. 64, no. 24, 2004, pages 2813 - 2820
T.W. GREENE, P.G. WUTS: "Frotective Groups in Organic Synthesis", 1999
Attorney, Agent or Firm:
ISHIBASHI Koki et al. (c/o DAIICHI SANKYO COMPANY, LIMITED, 1-16-13, Kitakasai, Edogawa-ku, Tokyo, JP)
Kimiki Ishibashi (1-16-13, Kita-Kasai, Edogawa-ku, Tokyo, 1340081 Inside Tokyo of DAIICHI SANKYO Co., Ltd., JP)
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