Title:
METHOD FOR PRODUCING C4 DICARBOXYLIC ACID
Document Type and Number:
WIPO Patent Application WO/2018/003641
Kind Code:
A1
Abstract:
Provided is an improvement in C4 dicarboxylic acid productivity in a host cell.
A polypeptide that comprises the amino acid sequence represented by SEQ ID NO:2 or an amino acid sequence having 90% or more sequence identity to the aforesaid sequence.
Inventors:
NONAKA KYOSHIRO (JP)
TAKAHASHI FUMIKAZU (JP)
TAKAHASHI FUMIKAZU (JP)
Application Number:
PCT/JP2017/022943
Publication Date:
January 04, 2018
Filing Date:
June 22, 2017
Export Citation:
Assignee:
KAO CORP (JP)
International Classes:
C12N15/09; C12N1/15; C12N9/02; C12P7/46
Domestic Patent References:
| WO2013028512A1 | 2013-02-28 | |||
| WO2010111344A2 | 2010-09-30 | |||
| WO2009155382A1 | 2009-12-23 | |||
| WO2014018755A1 | 2014-01-30 | |||
| WO2009011974A1 | 2009-01-22 | |||
| WO2016106367A1 | 2016-06-30 | |||
| WO2017065167A1 | 2017-04-20 | |||
| WO2017073640A1 | 2017-05-04 |
Foreign References:
| CN103013843A | 2013-04-03 |
Other References:
DATABASE Database GenBank 18 July 2006 (2006-07-18), "ROE00000398 Rhizopus oryzae Company Rhizopus oryzae cDNA , mRNA sequence", XP055450587, Database accession no. EE009190.1
DATABASE GenBank 23 March 2015 (2015-03-23), "hypothetical protein R03G _ 10751 [Rhizopus delemar RA 99-880", XP055450592, Database accession no. EIE86040
DATABASE Database GenBank [O] 23 March 2015 (2015-03-23), "Rhizopus oryzae RA 99-880 supercont. genomic scaffold, whole genome shotgun sequence", XP055450594, Database accession no. CH476739.1
MA LJ ET AL.: "Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole- genome duplication", PLOS GENET, vol. 5, 2009, pages e1000549, XP055148355
ZHANG B ET AL.: "Metabolic engineering of Rhizopus oryzae: Effects of overexpressing fumR gene on cell growth and fumaric acid biosynthesis from glucose", PROCESS BIOCHEM., vol. 47, 2012, pages 2159 - 2165, XP028960428
ZHANG B ET AL.: "Metabolic engineering of Rhizopus oryzae: effects of overexpressing pyc and pepc genes on fumaric acid biosynthesis from glucose", METAB. ENG., vol. 14, 2012, pages 512 - 520, XP055450601
HEWETT-EMMETT D ET AL.: "Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families", MOL. PHYLOGENET. EVOL., vol. 5, 1996, pages 50 - 77, XP002190992
PARK JY ET AL.: "CO2 reduction and organic compounds production by photosynthetic bacteria with surface displayed carbonic anhydrase and inducible expression of phosphoenolpyruvate carboxylase", ENZYME AND MICROBIAL TECHNOLOGY, vol. 96, 13 October 2016 (2016-10-13), pages 103 - 110, XP055450603
DATABASE GenBank 23 March 2015 (2015-03-23), "hypothetical protein R03G _ 10751 [Rhizopus delemar RA 99-880", XP055450592, Database accession no. EIE86040
DATABASE Database GenBank [O] 23 March 2015 (2015-03-23), "Rhizopus oryzae RA 99-880 supercont. genomic scaffold, whole genome shotgun sequence", XP055450594, Database accession no. CH476739.1
MA LJ ET AL.: "Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole- genome duplication", PLOS GENET, vol. 5, 2009, pages e1000549, XP055148355
ZHANG B ET AL.: "Metabolic engineering of Rhizopus oryzae: Effects of overexpressing fumR gene on cell growth and fumaric acid biosynthesis from glucose", PROCESS BIOCHEM., vol. 47, 2012, pages 2159 - 2165, XP028960428
ZHANG B ET AL.: "Metabolic engineering of Rhizopus oryzae: effects of overexpressing pyc and pepc genes on fumaric acid biosynthesis from glucose", METAB. ENG., vol. 14, 2012, pages 512 - 520, XP055450601
HEWETT-EMMETT D ET AL.: "Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families", MOL. PHYLOGENET. EVOL., vol. 5, 1996, pages 50 - 77, XP002190992
PARK JY ET AL.: "CO2 reduction and organic compounds production by photosynthetic bacteria with surface displayed carbonic anhydrase and inducible expression of phosphoenolpyruvate carboxylase", ENZYME AND MICROBIAL TECHNOLOGY, vol. 96, 13 October 2016 (2016-10-13), pages 103 - 110, XP055450603
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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