Title:
METHOD FOR PRODUCING CHEMICAL SUBSTANCE
Document Type and Number:
WIPO Patent Application WO/2013/105652
Kind Code:
A1
Abstract:
[Problem] To provide a method for producing a chemical substance with high yield using a mixed sugar composed of a hexose and a pentose as a fermentation raw material. [Solution] Provided is a method for producing a chemical substance through continuous fermentation, said method comprising filtrating a culture solution of a microorganism using a separation membrane, retaining an unfiltered portion of the culture solution in the culture solution or refluxing the unfiltered portion through the culture solution, adding a new fermentation raw material to the culture solution and collecting a product from the culture solution, wherein the fermentation raw material comprises a pentose and a hexose and the microorganism has a pathway through which a pentose can be metabolized with a pentose reductase and a pentol dehydrogenase.
Inventors:
WATANABE SHIOMI (JP)
KOBAYASHI KOJI (JP)
ISOBE KYOHEI (JP)
SAWAI KENJI (JP)
NA KYUNGSU (JP)
HIRAMATSU SHINGO (JP)
YAMADA KATSUSHIGE (JP)
KOBAYASHI KOJI (JP)
ISOBE KYOHEI (JP)
SAWAI KENJI (JP)
NA KYUNGSU (JP)
HIRAMATSU SHINGO (JP)
YAMADA KATSUSHIGE (JP)
Application Number:
PCT/JP2013/050437
Publication Date:
July 18, 2013
Filing Date:
January 11, 2013
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
C12P7/06; C12P7/56
Domestic Patent References:
| WO2007097260A1 | 2007-08-30 | |||
| WO2010067785A1 | 2010-06-17 | |||
| WO2007097260A1 | 2007-08-30 | |||
| WO2012086763A1 | 2012-06-28 | |||
| WO2010140602A1 | 2010-12-09 |
Foreign References:
| JP4770987B2 | 2011-09-14 | |||
| JP2009112289A | 2009-05-28 | |||
| JP2009028030A | 2009-02-12 | |||
| JP2011139707A | 2011-07-21 | |||
| JPH11506934A | 1999-06-22 | |||
| JP2005229821A | 2005-09-02 | |||
| JP2003212888A | 2003-07-30 | |||
| JP2001095597A | 2001-04-10 | |||
| JP3041380B2 | 2000-05-15 | |||
| JP2009112289A | 2009-05-28 |
Other References:
BICHO ET AL.: "Induction of Xylose Reductase and Xylitol Dehydrogenase Activities in Pachysolen tannophilus and Pichia stipitis on Mixed Sugars", APPL ENVIRON MICROBIOL, vol. 54, no. 1, 1988, pages 50 - 54, XP055080729
KARHUMAA ET AL.: "Comparison of the xylose reductase-xylitol dehydrogenase and the xylose isomerase pathways for xylose fermentation by recombinant Saccharomyces cerevisiae", MICROBIAL CELL FACTORIES, vol. 6, no. 5, 2007, pages 1 - 10, XP021024086
KIM ET AL.: "Batch and continuous fermentation of succinic acid from wood hydrolysate by Mannheimia succiniciproducens MBEL55E", ENZYME AND MICROBIAL TECHNOLOGY, vol. 35, 2004, pages 648 - 653, XP004619965
FOND ET AL.: "The acetone butanol fermentation on glucose and xylose. I. Regulation and kinetics in batch cultures", BIOTECHNOLOGY AND BIOENGINEERING, vol. XXVIII, 1986, pages 160 - 166, XP055080755
SUSAN T. TOON ET AL.: "Enhanced Cofermentation of Glucose and Xylose by Recombinant Saccharomyces Yeast Strains in Batch and Continuous Operating Modes.", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY., vol. 63-65, 1997, pages 243 - 255, XP000973510, DOI: doi:10.1007/BF02920428
A. ADEN ET AL.: "Lignocellulosic Biomass to Ethanol Process Design and Economics Utilizing Co-Current Dilute Acid Prehydrolysis and Enzymatic Hydrolysis for Corn Stover", NREL TECHNICAL REPORT, 2002
GREGORY N. STEPHANOPOULOS: "Metabolic Engineering: Principles and Methodologies", 2002, TOKYO DENKI UNIVERSITY PRESS, pages: 174
THE SOCIETY FOR BIOTECHNOLOGY, JAPAN: "Laboratory Manual for Bioengineering. The Society for Biotechnology", 1992, BAIFUKAN CO., LTD., pages: 310
See also references of EP 2803730A4
KARHUMAA ET AL.: "Comparison of the xylose reductase-xylitol dehydrogenase and the xylose isomerase pathways for xylose fermentation by recombinant Saccharomyces cerevisiae", MICROBIAL CELL FACTORIES, vol. 6, no. 5, 2007, pages 1 - 10, XP021024086
KIM ET AL.: "Batch and continuous fermentation of succinic acid from wood hydrolysate by Mannheimia succiniciproducens MBEL55E", ENZYME AND MICROBIAL TECHNOLOGY, vol. 35, 2004, pages 648 - 653, XP004619965
FOND ET AL.: "The acetone butanol fermentation on glucose and xylose. I. Regulation and kinetics in batch cultures", BIOTECHNOLOGY AND BIOENGINEERING, vol. XXVIII, 1986, pages 160 - 166, XP055080755
SUSAN T. TOON ET AL.: "Enhanced Cofermentation of Glucose and Xylose by Recombinant Saccharomyces Yeast Strains in Batch and Continuous Operating Modes.", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY., vol. 63-65, 1997, pages 243 - 255, XP000973510, DOI: doi:10.1007/BF02920428
A. ADEN ET AL.: "Lignocellulosic Biomass to Ethanol Process Design and Economics Utilizing Co-Current Dilute Acid Prehydrolysis and Enzymatic Hydrolysis for Corn Stover", NREL TECHNICAL REPORT, 2002
GREGORY N. STEPHANOPOULOS: "Metabolic Engineering: Principles and Methodologies", 2002, TOKYO DENKI UNIVERSITY PRESS, pages: 174
THE SOCIETY FOR BIOTECHNOLOGY, JAPAN: "Laboratory Manual for Bioengineering. The Society for Biotechnology", 1992, BAIFUKAN CO., LTD., pages: 310
See also references of EP 2803730A4
Attorney, Agent or Firm:
TANIGAWA AND PARTNERS, PATENT FIRM (JP)
Patent business corporation mountain stream international patent firm (JP)
Patent business corporation mountain stream international patent firm (JP)
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