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Title:
METHOD FOR PRODUCING CHEMICAL SUBSTANCE
Document Type and Number:
WIPO Patent Application WO/2013/105653
Kind Code:
A1
Abstract:
[Problem] To provide a method for producing a chemical substance with high yield using a mixed sugar composed of a hexose and a pentose as a fermentation raw material. [Solution] Provided is a method for producing a chemical substance through continuous fermentation, said method comprising filtrating a culture solution of a microorganism using a separation membrane, retaining an unfiltered portion of the culture solution in the culture solution or refluxing the unfiltered portion through the culture solution, adding a new fermentation raw material to the culture solution and collecting a product from the culture solution, wherein the fermentation raw material comprises a pentose and a hexose and the microorganism has a pathway through which a pentose can be metabolized with a pentose isomerase.

Inventors:
ISOBE KYOHEI (JP)
WATANABE SHIOMI (JP)
KOBAYASHI KOJI (JP)
SAWAI KENJI (JP)
NA KYUNGSU (JP)
HIRAMATSU SHINGO (JP)
YAMADA KATSUSHIGE (JP)
Application Number:
PCT/JP2013/050438
Publication Date:
July 18, 2013
Filing Date:
January 11, 2013
Export Citation:
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Assignee:
TORAY INDUSTRIES (JP)
International Classes:
C12P7/06; C12P7/18; C12P7/56
Domestic Patent References:
WO2007097260A12007-08-30
WO2010067785A12010-06-17
WO2007097260A12007-08-30
WO2012086763A12012-06-28
Foreign References:
JP4770987B22011-09-14
JP2009028030A2009-02-12
JP2011139707A2011-07-21
JPH11506934A1999-06-22
JP2005229821A2005-09-02
JP2003212888A2003-07-30
JP2001095597A2001-04-10
JP3041380B22000-05-15
JP2008079564A2008-04-10
JP2006525029A2006-11-09
Other References:
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TANAKA ET AL.: "Two different pathways for D- xylose metabolism and the effectof xylose concentration on the yield coefficient of L- lactate in mixed-acidfermentation by the lactic acid bacterium Lactococcus lactis 10-1", APPL MICROBIOL BIOTECHNOL, vol. 60, 2002, pages 160 - 167, XP009148218
ERLANDSON ET AL.: "Dissolution of Xylose Metabolism inLactococcus lactis", APPL. ENVIRON. MICROBIOL., vol. 66, no. 9, 2000, pages 3974 - 3980, XP002578206
FOND ET AL.: "The acetone butanol fermentation on glucose and xylose. I. Regulation and kinetics in batch cultures", BIOTECHNOLOGY AND BIOENGINEERING, vol. XXVIII, 1986, pages 160 - 166, XP055080755
KIM ET AL.: "Batch and continuous fermentation of succinic acid from wood hydrolysate by Mannheimia succiniciproducens MBEL55E", ENZYME AND MICROBIAL TECHNOLOGY, vol. 35, 2004, pages 648 - 653, XP004619965
KAISA KARHUMAA; ROSA GARCIA SANCHEZ; BARBEL HAHN-HAGERDAL; MARIE-F GORWA-GRAUSLUND: "Comparison of the xylose reductase-xylitol dehydrogenase and the xylose isomerase pathways for xylose fermentation by recombinant Saccharomyces cerevisiae", MICROBIAL CELL FACTORIES, vol. 6, 2007, pages 5, XP021024086, DOI: doi:10.1186/1475-2859-6-5
DO YUN KIM; SEONG CHUN YIM; PYUNG CHEON LEE; WOO GI LEE; SANG YUP LEE; HO NAM CHANG: "Batch and continuous fermentation of succinic acid from wood hydrolysate by Mannheimia succiniciproducens MBEL55E", ENZYME AND MICROBIAL TECHNOLOGY, vol. 35, 2004, pages 648 - 653, XP004619965, DOI: doi:10.1016/j.enzmictec.2004.08.018
A. ADEN ET AL.: "Lignocellulosic Biomass to Ethanol Process Design and Economics Utilizing Co-Current Dilute Acid Prehydrolysis and Enzymatic Hydrolysis for Corn Stover", NREL TECHNICAL REPORT, 2002
THE SOCIETY FOR BIOTECHNOLOGY, JAPAN: "Laboratory Manual for Bioengineering", 1992, BAIFUKAN CO., LTD., pages: 310
See also references of EP 2803731A4
Attorney, Agent or Firm:
TANIGAWA AND PARTNERS, PATENT FIRM (JP)
Patent business corporation mountain stream international patent firm (JP)
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Claims: