METHOD OF PRODUCING DIPEPTIDE

WIPO Patent Application WO/2006/001379

A1

It is intended to provide a method of producing a dipeptide characterized by comprising culturing in a medium a microorganism which has an ability to produce a protein having an activity of forming a dipeptide from one or more amino acids and also has an ability to produce at least one amino acid from among the one or more amino acids as described above, thus forming and accumulating the dipeptide in the medium and then harvesting the dipeptide from the medium.

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HASHIMOTO SHIN-ICHI
TABATA KAZUHIKO

PCT/JP2005/011636

January 05, 2006

June 24, 2005

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KYOWA HAKKO KOGYO KK (JP)
HASHIMOTO SHIN-ICHI
TABATA KAZUHIKO

A61K38/04; C07K5/062; C12N9/00; C12P21/02; C12P21/06; (IPC1-7): C12N15/52; C12N9/00; C12P21/02

WO2004000879A1

2003-12-31

HENRICH B. ET AL: "Peptidase D gene (pepD) of Escherichia coli K-12: nucleotide sequence, transcript mapping, and comparison with other peptide genes.", J BACTERIOL., vol. 172, no. 8, 1990, pages 4641 - 4651, XP002334249
OLSON E.R. ET AL: "Identification and characterization of dppA, an Escherichia coli gene encoding a periplasmic dipeptide transport protein.", J BACTERIOL., vol. 173, no. 1, 1991, pages 234 - 244, XP002991770

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