METHOD FOR PRODUCING EMBRYO BY IN VITRO CULTURE, AND METHOD, DEVICE, AND SYSTEM FOR SELECTING EMBRYO

Title:

METHOD FOR PRODUCING EMBRYO BY IN VITRO CULTURE, AND METHOD, DEVICE, AND SYSTEM FOR SELECTING EMBRYO

Document Type and Number:

WIPO Patent Application WO/2012/002500

Kind Code:

A1

Abstract:

Provided are means for efficiently obtaining a mammalian embryo having a high conception rate. A method for selecting a mammalian embryo obtained by in vitro culture from a fertilized egg comprises a step for selecting an embryo using two or more indicators selected from: the time from when fertilization takes place until a first cleavage is completed; the form at the stage after the first cleavage but before a second cleavage; the form at the stage after a third cleavage but before a fourth cleavage; and the amount of oxygen consumed at the early blastocyst stage, the blastocyst stage, or the hatched blastocyst stage.

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Inventors:

AKAI TOMONORI (JP)
IMAI KEI (JP)
AIKAWA YOSHIO (JP)
OHTAKE MASAKI (JP)
SUGIMURA SATOSHI (JP)

Application Number:

PCT/JP2011/065070

Publication Date:

January 05, 2012

Filing Date:

June 30, 2011

Export Citation:

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Assignee:

DAINIPPON PRINTING CO LTD (JP)
AKAI TOMONORI (JP)
IMAI KEI (JP)
AIKAWA YOSHIO (JP)
OHTAKE MASAKI (JP)
SUGIMURA SATOSHI (JP)

International Classes:

C12Q1/02; A01K67/00; A01K67/02; C12N5/073

Foreign References:

JP2009539387A	2009-11-19
JP2002122568A	2002-04-26
JP2010004789A	2010-01-14

Other References:

SHIGEO AOYAGI ET AL.: "Quality Evaluation of in vitro-Produced Bovine Embryos by Respiration Measurment and Development of Semi-Automatic Instrument", JOURNAL OF JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY, vol. 55, no. 11, 2006, pages 847 - 854
DANG-NGUYEN, TQ ET AL.: "Evaluation of developmental competence of in vitro-produced porcine embryos based on the timing, pattern and evenness of the first cleavage and onset of the second cleavage.", J REPROD DEV., vol. 56, no. 6, December 2010 (2010-12-01), pages 593 - 600

Attorney, Agent or Firm:

HIRAKI Yusuke et al. (JP)
Yusuke Hiraki (JP)

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