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Patent Searching and Data


Title:
METHOD FOR PRODUCING EPOXY ALCOHOL COMPOUND
Document Type and Number:
WIPO Patent Application WO/2019/031240
Kind Code:
A1
Abstract:
The present invention makes it possible to obtain a compound represented by formula (II) at a high yield by executing: a step A for obtaining a trimethyl oxosulfonium ylide solution or a trimethyl sulfonium ylide solution by reacting a base and a trimethyl oxosulfonium salt or a trimethyl sulfonium salt with one another in a solvent, and removing the solid which is produced; and a step B for obtaining a compound represented by formula (II) by reacting the solution obtained in step A with a compound represented by formula (I) (In the formula, Ar represents a phenyl group which may be substituted with one to three substituent groups selected from the group consisting of a halogen atom and a trifluoromethyl group, and R represents a hydrogen atom or a C1-12 alkyl group). It is possible to derive from the compound represented by formula (II) a compound represented by formula (V), which is useful as a production intermediate for an antifungal agent.

Inventors:
ANDO, Kenichi (LIMITED 1-21, Utajima 3-chome, Nishiyodogawa-ku, Osaka-sh, Osaka 21, 〒5550021, JP)
TANAKA, Yohei (LIMITED 1-21, Utajima 3-chome, Nishiyodogawa-ku, Osaka-sh, Osaka 21, 〒5550021, JP)
KAWAMI, Koh (LIMITED 4-1, Kojimatanokuchi 6-chome, Kurashiki-sh, Okayama 03, 〒7110903, JP)
Application Number:
JP2018/027835
Publication Date:
February 14, 2019
Filing Date:
July 25, 2018
Export Citation:
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Assignee:
SUMITOMO CHEMICAL COMPANY, LIMITED (27-1, Shinkawa 2-chome Chuo-k, Tokyo 60, 〒1048260, JP)
International Classes:
C07D301/02; C07D249/08; C07D303/12; C07D303/14; C07D405/06
Domestic Patent References:
WO2012053659A12012-04-26
WO2004000826A12003-12-31
Foreign References:
JPH07500569A1995-01-19
JP2004513934A2004-05-13
Attorney, Agent or Firm:
NAKAYAMA, Tohru et al. (LIMITED 5-33, Kitahama 4-chome, Chuo-ku, Osaka-sh, Osaka 50, 〒5418550, JP)
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