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Title:
METHOD FOR PRODUCING ETHER PHOSPHOLIPIDS
Document Type and Number:
WIPO Patent Application WO/2016/181491
Kind Code:
A1
Abstract:
[Problem] To provide a method for producing highly pure ether phospholipids free of plasmalogen glycerophospholipids by a simple operation. [Solution] This production method includes a step (a) for extracting the total lipids from a biological material by a mixed solution of a nonpolar organic solvent and a branched alcohol and a step (b) for decomposing the admixed diacyl phospholipids by causing phospholipase A1 to act on the total lipids obtained in step (a). This makes it possible to produce highly pure ether phospholipids free of plasmalogen glycerophospholipids by a simple operation.

Inventors:
FUJINO TAKEHIKO (JP)
MAWATARI SHIRO (JP)
Application Number:
PCT/JP2015/063617
Publication Date:
November 17, 2016
Filing Date:
May 12, 2015
Export Citation:
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Assignee:
FUJINO TAKEHIKO (JP)
MAWATARI SHIRO (JP)
International Classes:
C07F9/10; C11B11/00; C12P9/00
Domestic Patent References:
WO2012039472A12012-03-29
Foreign References:
JP2009227765A2009-10-08
JP2013053110A2013-03-21
JP2013053109A2013-03-21
Other References:
S.MAWATARI ET AL.: "Simultaneous Preparation of Purified Plasmalogens and Sphingomyelin in Human Erythrocytes with Phospholipase A1 from Aspergillus orizae", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, vol. 73, no. 12, 2009, pages 2621 - 2625, XP055330963
See also references of EP 3309242A4
Attorney, Agent or Firm:
KOHDA, MASAHIRO (JP)
Masahiro Koda (JP)
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