Title:
METHOD FOR PRODUCING FREEZE-DRIED PREPARATION
Document Type and Number:
WIPO Patent Application WO/2016/056527
Kind Code:
A1
Abstract:
The present invention addresses the main problem of providing a novel method for producing a freeze-dried preparation (combination drug) for injection that comprises tazobactam sodium and piperacillin sodium.
An example of the production method according to the present invention is as follows.
A method for producing a freeze-dried preparation for injection, said method being characterized by comprising:
(a) a step for blowing carbon dioxide gas into an aqueous sodium hydroxide solution; and
(b) a step for dissolving tazobactam and piperacillin in the solution obtained in step (a).
According to the present invention, a freeze-dried preparation showing good defoaming performance after redissolution can be obtained.
Inventors:
HARUNA SEIJI (JP)
BIRUKAWA DAIKI (JP)
BIRUKAWA DAIKI (JP)
Application Number:
PCT/JP2015/078269
Publication Date:
April 14, 2016
Filing Date:
October 06, 2015
Export Citation:
Assignee:
SAWAI SEIYAKU KK (JP)
International Classes:
A61K31/43; A61K9/19; A61K47/02; A61P31/04
Foreign References:
| JP2009518355A | 2009-05-07 |
Attorney, Agent or Firm:
SHIMIZU NAOTO (JP)
Hisato Shimizu (JP)
Hisato Shimizu (JP)
Download PDF: