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Title:
METHOD FOR PRODUCING GEMINAL DIFLUORO COMPOUND
Document Type and Number:
WIPO Patent Application WO/2016/052353
Kind Code:
A1
Abstract:
 Provided is a novel method for producing a geminal difluoro compound. A novel production method for obtaining a geminal difluoro compound represented by formula (2) at a high yield by reacting a compound represented by formula (1) with a fluorinating agent in the presence of an N-chloroimide compound. (In the formula, R1 indicates a C1-4 alkyl, X indicates a halogen atom.) 

Inventors:
NAGAYA AKIHIRO (JP)
KONDO SHOICHI (JP)
TAKEOKA JUN (JP)
NAKANO SATOSHI (JP)
Application Number:
PCT/JP2015/077175
Publication Date:
April 07, 2016
Filing Date:
September 25, 2015
Export Citation:
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Assignee:
NISSAN CHEMICAL IND LTD (JP)
International Classes:
C07C17/093; C07C17/35; C07C25/02; C07C25/13; C07B61/00
Domestic Patent References:
WO2012139775A12012-10-18
Foreign References:
JP2013180975A2013-09-12
JP2014510017A2014-04-24
JPH08500366A1996-01-16
Other References:
ROZEN S. ET AL.: "Conversion of the carbonyl group to CF2 using iodine monofluoride (IF", THE JOUNRAL OF ORGANIC CHEMISTRY, vol. 56, 1991, pages 4695 - 4700
YORK C. ET AL.: "Novel preparation of gem- difluorides from ketoximes with nitrosonium tetrafluoroborate and pyridinium", SYNLETT, vol. 6, 1994, pages 425 - 426
Attorney, Agent or Firm:
SENMYO, Kenji et al. (JP)
Spring name Kenji (JP)
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