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Title:
METHOD FOR PRODUCING HALOGEN-SUBSTITUTED PHTHALIDE
Document Type and Number:
WIPO Patent Application WO/2015/098716
Kind Code:
A1
Abstract:
A method for producing a halogen-substituted phthalide, which comprises the following steps (A) and (B). Step (A): A step wherein a halogen-substituted phthalic acid anhydride and sodium borohydride are reacted with each other in the presence of water in at least one solvent selected from the group consisting of ether solvents and alcohol solvents. Step (B): A step wherein some or all of the at least one solvent, which is selected from the group consisting of ether solvents and alcohol solvents and is contained in the reaction mixture obtained in the step (A), is substituted by an aromatic hydrocarbon solvent.

Inventors:
TORIUMI TATSUYA (JP)
Application Number:
PCT/JP2014/083636
Publication Date:
July 02, 2015
Filing Date:
December 15, 2014
Export Citation:
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Assignee:
SUMITOMO CHEMICAL CO (JP)
International Classes:
C07D307/88
Domestic Patent References:
WO2006093142A12006-09-08
Foreign References:
JP2011026295A2011-02-10
JP2005008642A2005-01-13
JP2007526916A2007-09-20
JP2001511144A2001-08-07
JPH06340580A1994-12-13
JP2002275138A2002-09-25
JP2003528882A2003-09-30
Other References:
ATSUKO NOSE ET AL.: "Reduction of Cyclic Carboxylic Anhydrides with Sodium Borohydride", JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, vol. 95, no. 11, 1975, pages 1390 - 1396
Attorney, Agent or Firm:
NAKAYAMA, Tohru et al. (JP)
Nakayama δΊ¨ (JP)
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