Title:
METHOD FOR PRODUCING HEAVY CHAIN DIAMINE
Document Type and Number:
WIPO Patent Application WO/2017/074065
Kind Code:
A1
Abstract:
The present invention relates to a method for producing a heavy chain diamine and, more specifically, to a method for producing a heavy chain diamine from an alcohol or alkane derived from a fatty acid, by culturing a recombinant microorganism from which a fatty aldehyde dehydrogenase gene in a ω-oxidative metabolic pathway and a β-oxidative metabolic pathway related gene have been removed, and also into which a ω-transaminase gene has been introduced. The recombinant microorganism disclosed in the present invention can prevent the additional oxidation and β-oxidation metabolism of fatty aldehyde and can produce a heavy chain diamine with a high yield by introducing an amine group to the terminus thereof.
Inventors:
AHN JUNG OH (KR)
LEE HONG WEON (KR)
PARK GYU YEON (KR)
LEE HEE SUK (KR)
JANG MIN JEONG (KR)
JEON WOO YOUNG (KR)
LEE HONG WEON (KR)
PARK GYU YEON (KR)
LEE HEE SUK (KR)
JANG MIN JEONG (KR)
JEON WOO YOUNG (KR)
Application Number:
PCT/KR2016/012174
Publication Date:
May 04, 2017
Filing Date:
October 27, 2016
Export Citation:
Assignee:
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
International Classes:
C12N15/70; C12N9/02; C12N9/10; C12N15/81; C12P13/00
Foreign References:
| JP2009096796A | 2009-05-07 | |||
| US9012227B2 | 2015-04-21 | |||
| KR101145405B1 | 2012-05-16 | |||
| US8530206B2 | 2013-09-10 |
Other References:
RUTTER ET AL.: "Engineering Yarrowia Lipolytica for Production of Medium-chain Fatty Acids", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 99, 1 July 2015 (2015-07-01), pages 7359 - 7368, XP002766854
Attorney, Agent or Firm:
BAE, KIM & LEE IP GROUP (KR)
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