Title:
METHOD FOR PRODUCING ISOCYANATE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2013/008891
Kind Code:
A1
Abstract:
Provided is a method for producing an isocyanate compound from an amine compound and a carbonate compound directly or continuously without requiring the isolation/purification of a carbamate compound that is generated as an intermediate. A method for producing an isocyanate compound represented by general formula (3), comprising the steps of: (A) reacting a carbonate compound represented by general formula (1) in the presence of an enzyme; and (B) (B1) bringing the reaction product from step (A) into contact, in a liquid phase, with a catalyst that comprises at least one metal compound selected from the group consisting of an alkali metal compound and an alkali earth metal compound supported on a carrier, or (B2) bringing the reaction product from step (A) into contact, in a gas phase, with a catalyst that comprises at least one metal compound selected from the group consisting of an alkali metal compound and an alkali earth metal compound supported on a carrier and/or a porous silica.
Inventors:
MATSUSHITA TOSHIYUKI
HARADA TAKASHI
KAWAGUCHI TATSUYA
YAMAMOTO YASUSHI
HARADA TAKASHI
KAWAGUCHI TATSUYA
YAMAMOTO YASUSHI
Application Number:
PCT/JP2012/067860
Publication Date:
January 17, 2013
Filing Date:
July 12, 2012
Export Citation:
Assignee:
UBE INDUSTRIES (JP)
MATSUSHITA TOSHIYUKI
HARADA TAKASHI
KAWAGUCHI TATSUYA
YAMAMOTO YASUSHI
MATSUSHITA TOSHIYUKI
HARADA TAKASHI
KAWAGUCHI TATSUYA
YAMAMOTO YASUSHI
International Classes:
C07C263/04; B01J23/02; B01J23/04; C07C265/04; C12P13/00; C07B61/00; C12N9/18; C12N9/20; C12N9/48; C12P7/26
Domestic Patent References:
| WO2012111750A1 | 2012-08-23 | |||
| WO2011083826A1 | 2011-07-14 |
Foreign References:
| JPH05186415A | 1993-07-27 | |||
| JPH05186414A | 1993-07-27 | |||
| JPS63183553A | 1988-07-28 |
Other References:
POZO, M. ET AL.: "Chiral carbamates through an enzymatic alkoxycarbonylation reaction", TETRAHEDRON, vol. 49, 1993, pages 4321 - 6
RIOS-LOMBARDIA, NICOLAS ET AL., JOURNAL OF ORGANIC CHEMISTRY, vol. 76, no. 14, 31 May 2011 (2011-05-31), pages 5709 - 18
BERKESSEL, A. ET AL.: "Enantiopure monoprotected cis-1,2-diaminocyclohexane: one-step preparation and application in asymmetric organocatalysis", CHEMCATCHEM, vol. 2, no. 10, 2010, pages 1215 - 8
RIOS-LOMBARDIA, NICOLAS ET AL., JOURNAL OF ORGANIC CHEMISTRY, vol. 76, no. 14, 31 May 2011 (2011-05-31), pages 5709 - 18
BERKESSEL, A. ET AL.: "Enantiopure monoprotected cis-1,2-diaminocyclohexane: one-step preparation and application in asymmetric organocatalysis", CHEMCATCHEM, vol. 2, no. 10, 2010, pages 1215 - 8
Attorney, Agent or Firm:
TSUKUNI & ASSOCIATES et al. (JP)
Patent business corporation Tsukuni (JP)
Patent business corporation Tsukuni (JP)
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Claims: