Title:
METHOD OF PRODUCING LIPIDS WITH HIGH EICOSAPENTAENOIC ACID CONTENT
Document Type and Number:
WIPO Patent Application WO/2016/031947
Kind Code:
A1
Abstract:
A lipid-producing microorganism is provided which can efficiently produce EPA. This mutant microorganism is obtained by introducing a foreign Δ17 desaturase gene, and one or more of a foreign Δ5 desaturase gene and a foreign Δ12 desaturase gene into a microorganism capable of producing ω9 highly unsaturated fatty acids or a microorganism having high arachidonic acid content in a fatty acid composition, and, after 10 days of culturing at 20°C or greater, the eicosapentaenoic acid content in the fatty acid composition is 20% or greater.
Inventors:
OGAWA JUN (JP)
ANDO AKINORI (JP)
SAKURADANI EIJI (JP)
SHIMIZU SAKAYU (JP)
HIRAMOTO SHIGERU (JP)
HARATA MASATAKA (JP)
TAKEMOTO YUKI (JP)
ANDO AKINORI (JP)
SAKURADANI EIJI (JP)
SHIMIZU SAKAYU (JP)
HIRAMOTO SHIGERU (JP)
HARATA MASATAKA (JP)
TAKEMOTO YUKI (JP)
Application Number:
PCT/JP2015/074346
Publication Date:
March 03, 2016
Filing Date:
August 28, 2015
Export Citation:
Assignee:
UNIV KYOTO (JP)
NISSHIN PHARMA INC (JP)
NISSHIN PHARMA INC (JP)
International Classes:
C12N1/15; C12N15/00; C12N15/09; C12P7/64
Domestic Patent References:
| WO2013192002A1 | 2013-12-27 | |||
| WO2008054565A1 | 2008-05-08 |
Foreign References:
| JP2014045740A | 2014-03-17 |
Other References:
AKINORI ANDO ET AL.: "EPA production under normal temperature by oleaginous filamentous fungus Mortierella alpine", BIOSCIENCE & INDUSTRY, vol. 71, no. 5, 1 September 2013 (2013-09-01), pages 441 - 443
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
Patent business corporation Alga patent firm (JP)
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