Title:
METHOD FOR PRODUCING MESOTHELIAL CELL, AND CELL SHEET FOR CONCRESCENCE PREVENTION
Document Type and Number:
WIPO Patent Application WO/2015/178498
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a method or the like for differentiating a mesodermal cell into a mesothelial cell. The present invention provides a method or the like for producing a mesothelial cell which includes a first cultivation step for cultivating a mesodermal cell in a culture medium containing basic fibroblast growth factor (bFGF) and oncostatin (M).
Inventors:
MIYAJIMA ATSUSHI (JP)
INAGAKI NATSUKO (JP)
INAGAKI FUYUKI (JP)
KOKUDO NORIHIRO (JP)
INAGAKI NATSUKO (JP)
INAGAKI FUYUKI (JP)
KOKUDO NORIHIRO (JP)
Application Number:
PCT/JP2015/064867
Publication Date:
November 26, 2015
Filing Date:
May 25, 2015
Export Citation:
Assignee:
UNIV TOKYO (JP)
International Classes:
C12N5/071
Domestic Patent References:
| WO2014115776A1 | 2014-07-31 |
Other References:
IZUMI ONITSUKA ET AL.: "Characterization and Functional Analyses of Hepatic Mesothelial Cells in Mouse Liver Development", GASTROENTEROLOGY, vol. 138, no. 4, 2010, pages 1525 - 1535, XP026985010, ISSN: 0016-5085
NATSUKO INAGAKI ET AL.: "Kan Chuhi Saibo Sheet o Mochiita Kan Setsujo-go no Yuchaku Boshi Oyobi Saisei Sokushin Ryoho no Kaihatsu", REGENERATIVE MEDICINE, vol. 12, 2013, pages 173, XP008185834
NATSUKO INAGAKI ET AL.: "Taka Ishoku ni Okeru Kan Chuhi Saibo Sheet no Yuyosei no Kento", REGENERATIVE MEDICINE, vol. 13, 27 January 2014 (2014-01-27), pages 251, XP008185833
NATSUKO INAGAKI ET AL.: "Kan Chuhi Saibo Sheet o Mochiita Jisedaigata Saisei Iryo", ACTA HEPATOLOGICA JAPONICA, vol. 54, no. 2, 2013, pages A590, XP008185656
EKITAI BAICHI·SAIBO BAIYO-YO SHIYAKU PAMPHLET, 2012, XP008185359
K INJI ASAHINA ET AL.: "Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development", HEPATOLOGY, vol. 49, no. 3, 2009, pages 998 - 1011, XP055238050, ISSN: 0270-9139
MINORU TANAKA ET AL.: "Liver stem/progenitor cells: their characteristics and regulatory mechanisms", J. BIOCHEMISTRY, vol. 149, no. 3, 2011, pages 231 - 239, XP055238052, ISSN: 0021-924x
See also references of EP 3147354A4
NATSUKO INAGAKI ET AL.: "Kan Chuhi Saibo Sheet o Mochiita Kan Setsujo-go no Yuchaku Boshi Oyobi Saisei Sokushin Ryoho no Kaihatsu", REGENERATIVE MEDICINE, vol. 12, 2013, pages 173, XP008185834
NATSUKO INAGAKI ET AL.: "Taka Ishoku ni Okeru Kan Chuhi Saibo Sheet no Yuyosei no Kento", REGENERATIVE MEDICINE, vol. 13, 27 January 2014 (2014-01-27), pages 251, XP008185833
NATSUKO INAGAKI ET AL.: "Kan Chuhi Saibo Sheet o Mochiita Jisedaigata Saisei Iryo", ACTA HEPATOLOGICA JAPONICA, vol. 54, no. 2, 2013, pages A590, XP008185656
EKITAI BAICHI·SAIBO BAIYO-YO SHIYAKU PAMPHLET, 2012, XP008185359
K INJI ASAHINA ET AL.: "Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development", HEPATOLOGY, vol. 49, no. 3, 2009, pages 998 - 1011, XP055238050, ISSN: 0270-9139
MINORU TANAKA ET AL.: "Liver stem/progenitor cells: their characteristics and regulatory mechanisms", J. BIOCHEMISTRY, vol. 149, no. 3, 2011, pages 231 - 239, XP055238052, ISSN: 0021-924x
See also references of EP 3147354A4
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
Yoshiyuki Inaba (JP)
Yoshiyuki Inaba (JP)
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