Title:
METHOD FOR PRODUCING MODIFIED BIOPOLYMER AND METHOD FOR CROSSLINKING BIOPOLYMERS
Document Type and Number:
WIPO Patent Application WO/2008/072379
Kind Code:
A1
Abstract:
It is intended to provide a method for chemically modifying a structure produced from gelatin or the like using a chemical compound with low volatility without dissolving the gelatin, and a method for crosslinking biopolymers for producing a biopolymer with high strength (high degree of crosslinking). According to the invention, a method for producing a modified biopolymer including the step of reacting a structure produced from a biopolymer with a compound which has a melting point of 50°C or higher and is in a solid state at a humidity of 50% or higher, and a method for crosslinking biopolymers, including the step of treating biopolymers with a crosslinking agent, characterized in that the concentration of the crosslinking agent in a reaction mixture is from 1.0 to 10% by weight, and crosslinking is carried out in the presence of an organofluorine compound are provided.
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Inventors:
OOYA SHOUJI (JP)
HIRATOU TETSUO (JP)
HIRATOU TETSUO (JP)
Application Number:
PCT/JP2007/001392
Publication Date:
June 19, 2008
Filing Date:
December 13, 2007
Export Citation:
Assignee:
FUJIFILM CORP (JP)
OOYA SHOUJI (JP)
HIRATOU TETSUO (JP)
OOYA SHOUJI (JP)
HIRATOU TETSUO (JP)
International Classes:
C08J7/12; A61K8/65; A61K8/73; A61K9/70; A61K47/36; A61K47/42; C08H1/00; C08J3/24; C08L89/04
Domestic Patent References:
| WO2005111121A2 | 2005-11-24 | |||
| WO1994027630A1 | 1994-12-08 | |||
| WO2010014176A2 | 2010-02-04 |
Foreign References:
| JPH04222559A | 1992-08-12 | |||
| JPH0698743A | 1994-04-12 | |||
| JPS52125613A | 1977-10-21 | |||
| JPH03259927A | 1991-11-20 | |||
| JP2004339395A | 2004-12-02 | |||
| JPH10265590A | 1998-10-06 | |||
| JP2002531182A | 2002-09-24 | |||
| JP2007224012A | 2007-09-06 | |||
| JP2004532802A | 2004-10-28 | |||
| JP2004321484A | 2004-11-18 | |||
| JPS642743B2 | 1989-01-18 | |||
| JP3639593B2 | 2005-04-20 | |||
| JP2002531182A | 2002-09-24 | |||
| US6992172B1 | 2006-01-31 |
Other References:
BRASH, TRANS. AM. SOC. ARTIF. INT. ORGANS, 1974, pages 69
BIOMATERIALS, vol. 27, no. 8, 2006, pages 452 - 1461
BIOMATERIALS, vol. 27, no. 8, 2006, pages 452 - 1461
Attorney, Agent or Firm:
SIKs & Co. (Kyobashi-Nisshoku Bldg. 8-7, Kyobashi1-chome, Chuo-k, Tokyo 31, JP)
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