Title:
METHOD FOR PRODUCING NON-HYDRATED FEXOFENADINE HYDROCHLORIDE AND A NOVEL CRYSTALLINE FORM OBTAINED THEREBY
Document Type and Number:
WIPO Patent Application WO2002066429
Kind Code:
A8
Abstract:
The invention relates to non-hydrated fexofenadine hydrochloride which can be obtained from a fexofenadine base and hydrogen chloride, according to the reaction conditions, either in the form of a novel polymorph ("form A"), in an amorphous form, or in the form of a mixture of different polymorphs. Said novel polymorph ("form A") can be used as a therapeutic active ingredient and can be processed to form a pharmaceutical containing the same and a pharmaceutically acceptable carrier. Said pharmaceutical is suitable for use as an antihistaminic agent, an antiallergic agent and/or a bronchodilating agent.
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Inventors:
KIRSCH VOLKER (CH)
Application Number:
PCT/CH2002/000027
Publication Date:
November 06, 2003
Filing Date:
January 17, 2002
Export Citation:
Assignee:
CILAG AG (CH)
KIRSCH VOLKER (CH)
KIRSCH VOLKER (CH)
International Classes:
A61K31/445; A61P11/08; A61P37/08; A61P43/00; C07D211/22; (IPC1-7): C07D211/22
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