Title:
METHOD FOR PRODUCING NOVEL MELANOIDIN HAVING ANTIBACTERIAL ACTIVITY, AND APPLICATION FOR SAME
Document Type and Number:
WIPO Patent Application WO/2023/067825
Kind Code:
A1
Abstract:
The present invention provides, inter alia: a method for producing an antibacterial composition, the method including producing a melanoidin by heating a reducing sugar selected from xylose or ribose, and an amino acid selected from phenylalanine or proline, and blending the melanoidin as an active ingredient; an antibacterial composition comprising a melanoidin produced as a reaction substrate from phenylalanine and xylose or ribose, and/or a melanoidin produced as a reaction substrate from proline and xylose or ribose; and an antibacterial composition comprising a compound represented by the given formula or a salt thereof. [In the formula, R1 to R10 each independently denote hydrogen (H) or a C1-5 branched or linear hydrocarbon group that may be saturated or unsaturated.]
Inventors:
KOSEKI SHIGENOBU (JP)
KITAOKA NAOKI (JP)
MATSUURA HIDEYUKI (JP)
KITAOKA NAOKI (JP)
MATSUURA HIDEYUKI (JP)
Application Number:
PCT/JP2022/013264
Publication Date:
April 27, 2023
Filing Date:
March 22, 2022
Export Citation:
Assignee:
UNIV HOKKAIDO NAT UNIV CORP (JP)
International Classes:
A01N61/00; A01N43/36; A01P1/00; A23L3/3526; A23L3/3544; A61K31/40; A61P31/04; C07D207/327; A61K8/49; A61Q19/00
Foreign References:
| JPS5618170B1 | 1981-04-27 | |||
| JP2009171890A | 2009-08-06 |
Other References:
KUWABARA, SOKO; SIMIZU, USIO; YAJIMA, MIZUO: "Antimicrobial Nature of the Products of Sugar-Amino Acid Reaction Part 1. Factors Affecting the Antimicrobial Activity", NIPPON NOGEI KAGAKUKAISHI - JOURNAL OF THE AGRICULTURAL CHEMICAL SOCIETY OF JAPAN, NIPPON NOGEI KAGAKUKAI, TOKYO, JP, vol. 46, no. 2, 1 January 1972 (1972-01-01), JP , pages 89 - 93, XP009545390, ISSN: 0002-1407, DOI: 10.1271/nogeikagaku1924.46.89
ALAVEZ-ROSAS DAVID, MALDONADO-DOMÍNGUEZ MAURICIO, GONZÁLEZ-ANTONIO OSCAR, ROMERO-ÁVILA MARGARITA, MÉNDEZ-STIVALET JOSÉ, FLORES-PÉR: "Synthesis of 1,3- and 1,2,3-functionalized pyrroles via Ir(I)-catalyzed vinylation of allyl alcohols", CHEMISTRY OF HETEROCYCLIC COMPOUNDS, SPRINGER US, NEW YORK, vol. 53, no. 5, 1 May 2017 (2017-05-01), New York , pages 526 - 531, XP055872867, ISSN: 0009-3122, DOI: 10.1007/s10593-017-2087-8
ALAVEZ-ROSAS DAVID, MALDONADO-DOMÍNGUEZ MAURICIO, GONZÁLEZ-ANTONIO OSCAR, ROMERO-ÁVILA MARGARITA, MÉNDEZ-STIVALET JOSÉ, FLORES-PÉR: "Synthesis of 1,3- and 1,2,3-functionalized pyrroles via Ir(I)-catalyzed vinylation of allyl alcohols", CHEMISTRY OF HETEROCYCLIC COMPOUNDS, SPRINGER US, NEW YORK, vol. 53, no. 5, 1 May 2017 (2017-05-01), New York , pages 526 - 531, XP055872867, ISSN: 0009-3122, DOI: 10.1007/s10593-017-2087-8
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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