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Title:
METHOD FOR PRODUCING OPTICALLY ACTIVE BICYCLIC γ-AMINO ACID DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2015/005298
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a high purity optically active bicyclic γ-amino acid derivative. The means for accomplishing this purpose is a method for producing a compound represented by general formula (VII), or a salt thereof, by means of a mixture of compounds represented by general formula (I) and general formula (I') or by means of compound (I). Formula (I) and (I') [in the formulae, R1 and R2 each denote a C1-6 alkyl group or the like, and R3 denotes a cyano group or the like.]

Inventors:
NAKAMURA, Yoshitaka (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
UKAI, Kazutoshi (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
KITAWAKI, Takafumi (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
NAKAJIMA, Takumi (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
KITAGAWA, Yutaka (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
FURUYA, Yukito (LIMITED 3-8-3, Nihonbashi Honch, Chuo-ku Tokyo 23, 〒1030023, JP)
IMAI, Makoto (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
NUMAGAMI, Eiji (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
WAKAYAMA, Masakazu (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
SAITO, Ayako (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
Application Number:
JP2014/068101
Publication Date:
January 15, 2015
Filing Date:
July 08, 2014
Export Citation:
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Assignee:
DAIICHI SANKYO COMPANY,LIMITED (3-5-1, Nihonbashi HonchoChuo-k, Tokyo 26, 〒1038426, JP)
International Classes:
C07C205/50; C07C201/12; C07C201/16; C07C227/00; C07C227/42; C07C229/32; C07C253/10; C07C253/30; C07C253/34; C07C255/47; C07B57/00; C07B61/00
Domestic Patent References:
WO2010110361A12010-09-30
WO2013089188A12013-06-20
WO2013154066A12013-10-17
Foreign References:
JP4479974B22010-06-09
JP2010241796A2010-10-28
US20110130454A12011-06-02
JP2013245215A2013-12-09
US20140094623A12014-04-03
US20140094624A12014-04-03
US20060154929A12006-07-13
US20030220397A12003-11-27
US20040152779A12004-08-05
US20030078300A12003-04-24
US20100249229A12010-09-30
US20120071685A12012-03-22
Other References:
See also references of EP 2871176A4
Attorney, Agent or Firm:
ISHIBASHI Koki et al. (LIMITED 1-2-58, Hiromach, Shinagawa-ku Tokyo 05, 〒1400005, JP)
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