Title:
METHOD FOR PRODUCING OXO FATTY ACID AND RARE FATTY ACID
Document Type and Number:
WIPO Patent Application WO/2013/168310
Kind Code:
A1
Abstract:
The present invention provides a method for producing an oxo fatty acid and a rare fatty acid, such as a conjugated fatty acid, a hydroxylated fatty acid, or a partially saturated fatty acid, using four types of enzymes (fatty acid hydratase, hydroxylated fatty acid dehydrogenase, oxo fatty acid isomerase, and oxo fatty acid enone reductase) derived from, for instance, a lactobacillus such as Lactobacillus plantarum. The present invention further provides a method for the more efficient production of an oxo fatty acid and the like by the partial combined use of chemical oxidation.
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Inventors:
OGAWA JUN (JP)
KISHINO SHIGENOBU (JP)
SHIMIZU SAKAYU (JP)
YONEJIMA YASUNORI (JP)
KISHINO SHIGENOBU (JP)
SHIMIZU SAKAYU (JP)
YONEJIMA YASUNORI (JP)
Application Number:
PCT/JP2012/078747
Publication Date:
November 14, 2013
Filing Date:
November 06, 2012
Export Citation:
Assignee:
UNIV KYOTO (JP)
NITTO PHARMACEUTICAL IND LTD (JP)
NITTO PHARMACEUTICAL IND LTD (JP)
International Classes:
C12N15/09; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/02; C12P7/64; C12R1/25
Foreign References:
| JP2007259712A | 2007-10-11 | |||
| JP2008511312A | 2008-04-17 | |||
| JP2002017381A | 2002-01-22 |
Other References:
OGAWA, J. ET AL.: "Production of conjugated fatty acids by lactic acid bacteria.", J. BIOSCI. BIOENG., vol. 100, no. 4, 2005, pages 355 - 364
SHIGENOBU KISHINO: "Biseibutsu o Mochiita Sentakuteki na Kinosei Shishitsu Seisanho no Kakuritsu", NEW ENERGY AND INDUSTRIAL TECHNOLOGY DEVELOPMENT ORGANIZATION (NEDO) HEISEI 22 NENDO SANGYO GIJUTSU KENKYU JOSEI JIGYO KENKYU SEIKA HOKOKUSHO (SAISHU), 26 April 2012 (2012-04-26)
KISHINO, S. ET AL.: "Novel multi-component enzyme machinery in lactic acid bacteria catalyzing C=C double bond migration useful for conjugated fatty acid synthesis.", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 416, no. 1-2, 10 November 2011 (2011-11-10), pages 188 - 193, XP028392204, DOI: doi:10.1016/j.bbrc.2011.11.022
SHIGENOBU KISHINO ET AL.: "Nyusankin ni Okeru Fuhowa Shibosan no Howaka Hanno ni Kakawaru Kagi Koso no Hakken, 3C23a11", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY 2012 NENDO TAIKAI KOEN YOSHISHU, 5 March 2012 (2012-03-05)
JUN OGAWA ET AL.: "Chonai Saikin ni Tokui na Shishitsu Taisha 'Shibosan Howaka Hanno' ni Kan'yo suru Shinki Kosokei no Kino Kaiseki to Oyo", JOURNAL OF JAPAN FOUDATION OF APPLIED ENZYMOLOGY, vol. 46, 1 February 2012 (2012-02-01), pages 13 - 21
DATABASE REFSEQ 22 July 2009 (2009-07-22), "Definition: nitroreductase [Lactobacillus plantarum JDM1].", accession no. P003061658
DATABASE GENBANK 17 July 2009 (2009-07-17), "Definition: Lactobacillus plantarum JDM1, complete genome.", accession no. P001617
DEMIR, A.S. ET AL.: "Chemoenzymatic conversion of linoleic acid into conjugated linoleic acid.", J. AGRIC. FOOD CHEM., vol. 58, no. 3, 2010, pages 1646 - 1652
SHIGENOBU KISHINO: "Biseibutsu o Mochiita Sentakuteki na Kinosei Shishitsu Seisanho no Kakuritsu", NEW ENERGY AND INDUSTRIAL TECHNOLOGY DEVELOPMENT ORGANIZATION (NEDO) HEISEI 22 NENDO SANGYO GIJUTSU KENKYU JOSEI JIGYO KENKYU SEIKA HOKOKUSHO (SAISHU), 26 April 2012 (2012-04-26)
KISHINO, S. ET AL.: "Novel multi-component enzyme machinery in lactic acid bacteria catalyzing C=C double bond migration useful for conjugated fatty acid synthesis.", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 416, no. 1-2, 10 November 2011 (2011-11-10), pages 188 - 193, XP028392204, DOI: doi:10.1016/j.bbrc.2011.11.022
SHIGENOBU KISHINO ET AL.: "Nyusankin ni Okeru Fuhowa Shibosan no Howaka Hanno ni Kakawaru Kagi Koso no Hakken, 3C23a11", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY 2012 NENDO TAIKAI KOEN YOSHISHU, 5 March 2012 (2012-03-05)
JUN OGAWA ET AL.: "Chonai Saikin ni Tokui na Shishitsu Taisha 'Shibosan Howaka Hanno' ni Kan'yo suru Shinki Kosokei no Kino Kaiseki to Oyo", JOURNAL OF JAPAN FOUDATION OF APPLIED ENZYMOLOGY, vol. 46, 1 February 2012 (2012-02-01), pages 13 - 21
DATABASE REFSEQ 22 July 2009 (2009-07-22), "Definition: nitroreductase [Lactobacillus plantarum JDM1].", accession no. P003061658
DATABASE GENBANK 17 July 2009 (2009-07-17), "Definition: Lactobacillus plantarum JDM1, complete genome.", accession no. P001617
DEMIR, A.S. ET AL.: "Chemoenzymatic conversion of linoleic acid into conjugated linoleic acid.", J. AGRIC. FOOD CHEM., vol. 58, no. 3, 2010, pages 1646 - 1652
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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