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Title:
METHOD FOR PRODUCING PYRROLE DERIVATIVE, AND INTERMEDIATE THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/030010
Kind Code:
A1
Abstract:
 The present invention provides a method for producing an atropisomer of a pyrrole derivative having an exceptional mineralocorticoid receptor antagonizing effect, and an intermediate thereof. A method for producing an atropisomer of a pyrrole derivative using a compound represented by (B) [in the formula, R1 indicates a C1-C4 alkyl group, and R2 indicates a 2-hydroxyethyl group or carboxymethyl group] as a production intermediate.

Inventors:
WATANABE, Masashi (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
NAGASAWA, Hiroshi (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
SATO, Noritada (LIMITED 1-12-1, Shinomiy, Hiratsuka-shi Kanagawa 14, 〒2540014, JP)
Application Number:
JP2014/072332
Publication Date:
March 05, 2015
Filing Date:
August 26, 2014
Export Citation:
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Assignee:
DAIICHI SANKYO COMPANY,LIMITED (3-5-1, Nihonbashi HonchoChuo-k, Tokyo 26, 〒1038426, JP)
International Classes:
C07D207/456; C07B57/00; C12P41/00
Domestic Patent References:
WO2010098286A12010-09-02
WO2008126831A12008-10-23
WO2006012642A22006-02-02
WO2006012642A22006-02-02
WO2008126831A12008-10-23
Foreign References:
JP2010111657A2010-05-20
JP2012505225A2012-03-01
US20080234270A12008-09-25
US20100093826A12010-04-15
Other References:
See also references of EP 3040330A4
Attorney, Agent or Firm:
ISHIBASHI Koki et al. (LIMITED 1-2-58, Hiromach, Shinagawa-ku Tokyo 05, 〒1400005, JP)
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