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Title:
METHOD FOR PRODUCING REGENERATIVE ORGAN PRIMORDIUM PROVIDED WITH GUIDE FOR TRANSPLANTATION, COMPOSITION CONTAINING REGENERATIVE ORGAN PRIMORDIUM PROVIDED WITH GUIDE FOR TRANSPLANTATION PRODUCED THEREBY, AND METHOD FOR TRANSPLANTING REGENERATIVE ORGAN PRIMORDIUM PROVIDED WITH GUIDE FOR TRANSPLANTATION
Document Type and Number:
WIPO Patent Application WO/2012/108069
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a method for producing a regenerative organ primordium for transplantation, said regenerative organ primordium for transplantation ensuring continuity with a recipient after transplantation and facilitating transplantation procedures. Provided is a method for producing a regenerative organ primordium provided with a guide for transplantation, said method comprising: a step for preparing a regenerative organ primordium by tightly contacting a first cell mass, which substantially consists of mesenchymal cells, with a second cell mass, which substantially consists of epithelial cells, and culturing these cell masses within a supporting medium; and a step for inserting the guide into the regenerative organ primordium.

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Inventors:
TOYOSHIMA KOH-EI (JP)
TSUJI TAKASHI (JP)
Application Number:
PCT/JP2011/067045
Publication Date:
August 16, 2012
Filing Date:
July 27, 2011
Export Citation:
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Assignee:
ORGAN TECHNOLOGIES INC (JP)
TOYOSHIMA KOH-EI (JP)
TSUJI TAKASHI (JP)
International Classes:
C12N5/071; A61L27/00; A61K35/12
Domestic Patent References:
WO2006129672A12006-12-07
WO2008105499A12008-09-04
WO2008090826A12008-07-31
WO2005014774A12005-02-17
WO2006129672A12006-12-07
Foreign References:
JP2008029757A2008-02-14
JP2008029756A2008-02-14
JP2008029756A2008-02-14
JP2008206500A2008-09-11
JP2008200033A2008-09-04
JP2008029757A2008-02-14
Other References:
SONOYAMA W ET AL.: "Mesenchymal stem cell-mediated functional tooth regeneration in swine.", PLOS ONE, vol. 1, 2006, pages E79, XP055116639, Retrieved from the Internet
KOEI TOYOSHIMA ET AL.: "Kikan Genki-ho ni yoru Mohatsu no Saisei I Sai Kosei Moho Genki no Hinai Ishoku ni yoru Mohatsu Saisei", REGENERATIVE MEDICINE, vol. 10, 1 February 2011 (2011-02-01), pages 276 - 2P-141, XP008169592
SHARPE PT; YOUNG CS, TEST-TUBE TEETH. SC. AM., vol. 293, 2005, pages 34 - 41
NAKAO K ET AL., NAT. METHODS, vol. 4, no. 3, 2007, pages 227 - 30
Attorney, Agent or Firm:
NANJO, Masahiro et al. (JP)
Masahiro Nanjo (JP)
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