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Title:
METHOD FOR PRODUCING SAME-CONTAINING MATERIAL, AND EXTERNAL AGENT, COSMETIC AND HEALTH FOOD COMPRISING SAME-CONTAINING LIQUID MATERIAL
Document Type and Number:
WIPO Patent Application WO/2018/042841
Kind Code:
A1
Abstract:
A SAMe-containing material having a high SAMe content can be obtained by a method which comprises: a heating/dissolving step for supplying water and brown sugar to a culture tank and dissolving the brown sugar by heating; a culture step for supplying a yeast to the culture tank and culturing the same; a separation step for separating the yeast from the culture medium by centrifugation; a lysis treatment step for subjecting the obtained yeast to a lysis treatment and thus disrupting the yeast cells; and an extraction step for conducting extraction with water under acidic conditions. In the culture step, the culture is terminated at a timing from a point when the turbidity of the liquid culture medium changes from rise to fall to a point when the turbidity falls by 15%. The obtained SAMe-containing material in a liquid form is usable in an external agent, a cosmetic or a health food in a cream, gel or liquid state.

Inventors:
MITSUI Yukio (3-3-5 NAKANO, NAKANO-K, Tokyo 01, 〒1640001, JP)
Application Number:
JP2017/023057
Publication Date:
March 08, 2018
Filing Date:
June 22, 2017
Export Citation:
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Assignee:
HORUS CO., LTD. (3-3-5 NAKANO, NAKANO-KU Tokyo, 01, 〒1640001, JP)
International Classes:
C12P17/18; A23L33/145; A23L33/17; A61K8/60; A61K8/99; A61K31/7076; A61P19/02; A61Q19/00; C07H19/167; C12P13/12
Domestic Patent References:
WO2013080265A12013-06-06
WO2010027014A12010-03-11
Foreign References:
JPS58146291A1983-08-31
JP2014217331A2014-11-20
JP2016041047A2016-03-31
JP2013047222A2013-03-07
JP2005027527A2005-02-03
Other References:
HORUS: "Fermented and Matured Placenta", SAME' DE KINOSEI HYOJI SHUTOKU E, THE SHUKAN, 21 April 2016 (2016-04-21), Retrieved from the Internet [retrieved on 20170904]
Attorney, Agent or Firm:
ABE Shinichi et al. (3rd Floor, KT Bldg. 3-11-12, Takad, Toshima-ku Tokyo 33, 〒1710033, JP)
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