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Title:
METHOD FOR PRODUCING STERILIZED VISCOUS BASE AND METHOD FOR PRODUCING MEDICINAL PREPARATION
Document Type and Number:
WIPO Patent Application WO/2019/022182
Kind Code:
A1
Abstract:
Provided is a method whereby a sterilized viscous base can be easily produced at a high sterilization efficiency. The method for producing a sterilized viscous base (base no. 5) comprises: a heat sterilization step for heat sterilizing an acidic solution of a viscosity-imparting agent (base no. 2) which shows a higher viscosity in a neutral range than in an acidic range; and a neutralization step for, after the heat sterilization step, neutralizing the heat sterilized product (base no. 3) of the acidic solution of the viscosity-imparting agent by adding a base thereto.

Inventors:
MINAMI KOHJI (JP)
GOMI YASUYUKI (JP)
OGAWA HIRONOBU (JP)
YAMAMOTO MAMI (JP)
KONDO TETSUYA (JP)
Application Number:
JP2018/028038
Publication Date:
January 31, 2019
Filing Date:
July 26, 2018
Export Citation:
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Assignee:
THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OF OSAKA UNIV (JP)
International Classes:
A61K9/08; A61K39/00; A61K45/00; A61K47/18; A61K47/32; A61P37/04
Foreign References:
JPH09508907A1997-09-09
JPH10508316A1998-08-18
JPH0338529A1991-02-19
Attorney, Agent or Firm:
TANAKA, Junya et al. (JP)
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