Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHOD FOR THE PRODUCTION OF PRAZIQUANTEL AND PRECURSORS THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/036577
Kind Code:
A8
Abstract:
The present invention provides methods of preparing Praziquantel, in particular (R)-Praziquantel and analogues thereof in a stereoselective manner. One method involves asymmetric hydrogenation of the following intermediate compound (I) and subsequent cyclization.

Inventors:
EBERHARDT, Luc (Hallgarterstrasse 7, Wiesbaden, 65197, DE)
WAECHTLER, Andreas (Hopfengarten 16, Darmstadt, 64295, DE)
MAILLARD, David (Martinstrasse 81, Darmstadt, 64285, DE)
LEHMANN, Stefan (Bachstrasse 23, Otzberg, 64853, DE)
Application Number:
EP2016/001376
Publication Date:
March 29, 2018
Filing Date:
August 10, 2016
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
MERCK PATENT GMBH (Frankfurter Strasse 250, Darmstadt, 64293, DE)
International Classes:
C07D217/14; C07B53/00
Download PDF: