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Title:
METHOD FOR PURIFYING PROTEIN
Document Type and Number:
WIPO Patent Application WO/2020/203718
Kind Code:
A1
Abstract:
A method for purifying a protein-containing solution that contains a target protein, said method comprising: (α1) a step for contacting the protein-containing solution with a porous medium containing a polyketone; and (α2) a step for passing the protein-containing solution, which has been contacted with the porous medium containing the polyketone, through a virus removal film.

Inventors:
FUTAMURA AKIKA (JP)
TANIGUCHI HIROKI (JP)
HIDAKA JUNJI (JP)
Application Number:
PCT/JP2020/013893
Publication Date:
October 08, 2020
Filing Date:
March 27, 2020
Export Citation:
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Assignee:
ASAHI KASEI MEDICAL CO LTD (JP)
International Classes:
B01D61/14; B01D15/00; B01D65/08; B01D69/00; B01D69/04; B01D71/44; B01J20/26; C07K1/34; C07K1/36; C07K16/00; C12P21/08
Domestic Patent References:
WO2016031834A12016-03-03
WO2013035747A12013-03-14
WO2016031834A12016-03-03
WO2003055934A12003-07-10
Foreign References:
JP2012519065A2012-08-23
JP2017205740A2017-11-24
JP2015203048A2015-11-16
JP2014173013A2014-09-22
JPS5659716A1981-05-23
JP2638680B21997-08-06
JP2015203048A2015-11-16
JP2005145852A2005-06-09
US20160176921A12016-06-23
JP2014151272A2014-08-25
Other References:
"HLC MAILGRAM", vol. 97, 25 August 2003, TOSOH CORP, pages: 10
MANABE. S: "Removal of virus through novel membrane filtration method", DEV. BIOL. STAND., vol. 88, 1996, pages 81 - 90
BRANDWEIN H ET AL.: "Membrane filtration for virus removal", DEV BIOL (BASEL, vol. 102, 2000, pages 157 - 63, XP055315724
ARANHA-CREADO ET AL.: "Clearance of murine leukaemia virus from monoclonal antibody solution by a hydrophilic PVDF microporous membrane filter", BIOLOGICALS, vol. 26, no. 2, June 1998 (1998-06-01), pages 167 - 72, XP001543186, DOI: 10.1006/biol.1998.0130
L. MOCE-LLIVINA ET AL.: "Comparison of polyvinylidene fluoride and polyether sulfone membranes in filtering viral suspensions", JOURNAL OF VIROLOGICAL METHODS, vol. 109, April 2003 (2003-04-01), pages 99 - 101
See also references of EP 3950099A4
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
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