Title:
METHOD FOR PURIFYING SUCRALOSE
Document Type and Number:
WIPO Patent Application WO/2022/099606
Kind Code:
A1
Abstract:
A method for purifying sucralose, comprising: removing a solvent from a sucralose reaction liquid to obtain a concentrated solution of a sucralose crude product; under stirring, adding ethyl acetate to the concentrated solution of the sucralose crude product, heating same to a preset temperature and maintaining the temperature for first preset time to obtain a crude product slurry containing some sucralose crystals; and reducing the temperature of the crude product slurry in a gradient manner to a temperature end point, maintaining the temperature for second preset time, and performing filtering to obtain sucralose crystals. The present invention has the advantages of simple and convenient operation, small treatment capacity, a less required solvent amount, etc.; in addition, no additional species is added to the process flow by using ethyl acetate, and the boiling point of ethyl acetate is much lower than that of butyl acetate, such that the energy consumption in the distillation removal and recovery process is greatly reduced, and thus, the production efficiency is improved, and the production cost is reduced.
Inventors:
LI ZHENGHUA (CN)
XIA JIAXIN (CN)
XU CHUANJIU (CN)
XU GUOJIA (CN)
XIA JIAXIN (CN)
XU CHUANJIU (CN)
XU GUOJIA (CN)
Application Number:
PCT/CN2020/128654
Publication Date:
May 19, 2022
Filing Date:
November 13, 2020
Export Citation:
Assignee:
ANHUI JINHE IND CO LTD (CN)
International Classes:
C07H1/06; C07H5/02
Foreign References:
| CN101177437A | 2008-05-14 | |||
| CN109503680A | 2019-03-22 | |||
| CN101768193A | 2010-07-07 | |||
| CN106188166A | 2016-12-07 | |||
| CN106674292A | 2017-05-17 | |||
| US5498709A | 1996-03-12 |
Other References:
See also references of EP 4215538A4
Attorney, Agent or Firm:
BEIJING LONGAN LAW FIRM (CN)
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