Title:
METHOD FOR REGENERATING URINARY TRACT TISSUE USING THREE-DIMENSIONAL CELL STRUCTURE
Document Type and Number:
WIPO Patent Application WO/2018/216228
Kind Code:
A1
Abstract:
The purpose of the present invention is to establish, as one of bladder regenerative medical techniques, novel treatment which transplants a bone marrow-derived cell structure into a bladder and attempts to regenerate a functional bladder. The present invention provides: a low-compliance bladder or a contracted bladder including a three-dimensional structure which is constructed by laminating spheroids of bone marrow-derived cells on a spicule disposed on a substrate and has a thickness of at least 500 μm; or tissue regeneration, a function enhancer or the like for a low-compliance bladder.
Inventors:
IMAMURA TETSUYA (JP)
SHIMAMURA MITSURU (JP)
SHIMAMURA MITSURU (JP)
Application Number:
PCT/JP2017/020531
Publication Date:
November 29, 2018
Filing Date:
May 26, 2017
Export Citation:
Assignee:
CYFUSE BIOMEDICAL KK (JP)
SHINSHU UNIV NATIONAL UNIV CORPORATION (JP)
SHINSHU UNIV NATIONAL UNIV CORPORATION (JP)
International Classes:
A61L27/38; A61K35/28; A61L27/40; A61P13/10; A61P15/00; A61P15/10
Domestic Patent References:
| WO2008123614A1 | 2008-10-16 | |||
| WO2007125420A2 | 2007-11-08 |
Other References:
TETSUYA IMAMURA ET AL.: "Bio 3D Printer de Sakusei shita Kotsuzui Yurai Saibo Kozotai ni yoru Hoshasen Shosha Shogai Boko no Kinoteki na Boko Saisei eno Kokoromi", REGENERATIVE MEDICINE, vol. 16, 1 February 2017 (2017-02-01), pages 284
TETSUYA IMAMURA ET AL.: "Bio 3D Printer de Sakusei shita Kotsuzui Yurai Saibo Kozotai o Mochiita Hoshasen Shosha Shogai Boko no Kinoteki na Boko Saisei eno Kokoromi", THE 13TH MEETING OF SOCIETY FOR RECONSTRUCTION AND REGENERATION IN UROLOGIC SURGERY PROGRAM SHOROKUSHU, 18 June 2016 (2016-06-18), pages 42
TETSUYA IMAMURA: "Saisei Iryo kenkyu ni okeru kinoteki na kabu nyoro soshiki no saisei o mezashita 'Jisedai Tissue Engineering", JAPANESE JOURNAL OF UROLOGICAL SURGERY, vol. 29, no. 1, 15 January 2016 (2016-01-15), pages 21 - 28
INOUE S. ET AL.: "Regeneration of rat corpus cavernosa tissue after transplantation of CD 133+ cells derived from human bone marrow and placement of biodegradable gel sponge sheet.", EUROPEAN UROLOGY, vol. 14, no. 2, 2015, pages e47
INOUE S. ET AL.: "REGENERATION OF RAT CORPUS CAVERNOSA TISSUE AFTER TRANSPLANTATION OF CD 133+ CELLS DERIVED FROM HUMAN BONE MARROW AND PLACEMENT OF BIODEGRADABLE GEL SPONGE SHEET", THE JOURNAL OF UROLOGY, vol. 193, no. 4S, 2015, pages e628
SUN C. ET AL.: "Neurotrophic effect of bone marrow mesenchymal stem cells for erectile dysfunction in diabetic rats", INTERNATIONAL JOURNAL OF ANDROLOGY, vol. 35, 2012, pages 601 - 607
TETSUYA IMAMURA ET AL.: "Bio 3D Printer de Sakusei shita Kotsuzui Yurai Saibo Kozotai o Mochiita Hoshasen Shosha Shogai Boko no Kinoteki na Boko Saisei eno Kokoromi", THE 13TH MEETING OF SOCIETY FOR RECONSTRUCTION AND REGENERATION IN UROLOGIC SURGERY PROGRAM SHOROKUSHU, 18 June 2016 (2016-06-18), pages 42
TETSUYA IMAMURA: "Saisei Iryo kenkyu ni okeru kinoteki na kabu nyoro soshiki no saisei o mezashita 'Jisedai Tissue Engineering", JAPANESE JOURNAL OF UROLOGICAL SURGERY, vol. 29, no. 1, 15 January 2016 (2016-01-15), pages 21 - 28
INOUE S. ET AL.: "Regeneration of rat corpus cavernosa tissue after transplantation of CD 133+ cells derived from human bone marrow and placement of biodegradable gel sponge sheet.", EUROPEAN UROLOGY, vol. 14, no. 2, 2015, pages e47
INOUE S. ET AL.: "REGENERATION OF RAT CORPUS CAVERNOSA TISSUE AFTER TRANSPLANTATION OF CD 133+ CELLS DERIVED FROM HUMAN BONE MARROW AND PLACEMENT OF BIODEGRADABLE GEL SPONGE SHEET", THE JOURNAL OF UROLOGY, vol. 193, no. 4S, 2015, pages e628
SUN C. ET AL.: "Neurotrophic effect of bone marrow mesenchymal stem cells for erectile dysfunction in diabetic rats", INTERNATIONAL JOURNAL OF ANDROLOGY, vol. 35, 2012, pages 601 - 607
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
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