Title:
METHOD FOR REGULATING GENE EXPRESSION
Document Type and Number:
WIPO Patent Application WO/2019/076355
Kind Code:
A1
Abstract:
A method of modifying an upstream open reading frame (uORF) by genome editing technique to regulate gene expression.
Inventors:
GAO CAIXIA (CN)
ZHANG HUAWEI (CN)
RAN YIDONG (CN)
ZHANG HUAWEI (CN)
RAN YIDONG (CN)
Application Number:
PCT/CN2018/110928
Publication Date:
April 25, 2019
Filing Date:
October 19, 2018
Export Citation:
Assignee:
INST GENETICS & DEVELOPMENTAL BIOLOGY CAS (CN)
TIANJIN GENOVO BIOTECHNOLOGY CO LTD (CN)
TIANJIN GENOVO BIOTECHNOLOGY CO LTD (CN)
International Classes:
C12N15/113; C12N5/10; C12N5/14
Domestic Patent References:
| WO2002020789A1 | 2002-03-14 |
Foreign References:
| CN101768591A | 2010-07-07 | |||
| CN104884622A | 2015-09-02 |
Other References:
NIVYA KOLLI ET AL.: "CRISPR-Cas9 Mediated Gene -Silencing of the Mutant Huntingtin Gene in an In Vitro Model of Huntington's Disease", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 18, no. 4, 2 April 2017 (2017-04-02), pages 754, XP055466760, ISSN: 1422-0067, DOI: 10.3390/ijms18040754
Attorney, Agent or Firm:
NTD PATENT AND TRADEMARK AGENCY LIMITED (CN)
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