Title:
METHOD FOR RESOLVING OPTICAL ISOMER BY USING SUPERCRITICAL FLUID EXTRACTION TECHNOLOGY
Document Type and Number:
WIPO Patent Application WO/2020/216295
Kind Code:
A1
Abstract:
Provided is a method for resolving an optical isomer from a raceme by using supercritical fluid extraction technology. The method is mainly applied to the separation of a product obtained after enzymatic resolution. Taking a preparation process of D-pantolactone as an example, the key point is to separate D-pantolactone and L-pantolactone from an enzymatic resolution liquid by means of supercritical fluid extraction.
Inventors:
LAU MAN KIT (CN)
SU JINHUAN (CN)
CHIEW ANSEN (CN)
CHEN YAN (CN)
ZENG CONGMING (CN)
SU JINHUAN (CN)
CHIEW ANSEN (CN)
CHEN YAN (CN)
ZENG CONGMING (CN)
Application Number:
PCT/CN2020/086420
Publication Date:
October 29, 2020
Filing Date:
April 23, 2020
Export Citation:
Assignee:
GUANG AN MOJIA BIOTECHNOLOGY CO LTD (CN)
International Classes:
C12P41/00; C12N9/18; C12N11/00; C12N11/08; C12P7/42
Foreign References:
| CN108117532A | 2018-06-05 | |||
| CN1926429A | 2007-03-07 | |||
| CN1935977A | 2007-03-28 | |||
| CN1313402A | 2001-09-19 |
Other References:
XIN YI: "Design of a supercritical fluid extraction, rectification, chromatography preparation device and its application", CHINESE MASTER'S THESES, no. 3, June 2016 (2016-06-01), pages 1 - 33, XP009532127
GAO LIHING: "Resolution of enantiomeric drugs by supercritical fluid extraction", MEDICINE AND PUBLIC HEALTH CHINESE SELECTED DOCTORAL DISSERTATION AND MASTERS THESES FULL-TEXT DATABASES, 1 July 2001 (2001-07-01), CN, pages 1 - 116, XP009532170
See also references of EP 3960871A4
GAO LIHING: "Resolution of enantiomeric drugs by supercritical fluid extraction", MEDICINE AND PUBLIC HEALTH CHINESE SELECTED DOCTORAL DISSERTATION AND MASTERS THESES FULL-TEXT DATABASES, 1 July 2001 (2001-07-01), CN, pages 1 - 116, XP009532170
See also references of EP 3960871A4
Attorney, Agent or Firm:
JUN HE LAW OFFICES (CN)
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