METHOD FOR SCREENING CANCER PREVENTION AGENT OR ANTICANCER AGENT USING MORPHOLOGICAL CHARACTERISTICS OF LUTERIAL

WIPO Patent Application WO/2015/108342

A1

The present invention relates to a method for screening a cancer prevention agent or an anticancer agent, the method comprising the steps of: (a) isolating mutant luterial or normal luterial from body fluids previously eliminated from a patient or a normal person; (b) treating the isolated mutant luterial with candidates for an anticancer agent or cancer prevention agent; and (c) selecting, as an anticancer agent, a candidate which reduces the size of the mutant luterial, changes the shape of the mutant luterial, or increases mobility of the mutant luterial compared with a control group before the treatment with the candidates, or selecting, as a cancer prevention agent, a candidate which suppresses the size increase of luterial, minimizes the morphological change of luterial, or maintains mobility of luterial compared with a control group before the treatment with the candidates.

CHOI WON CHEOL (KR)
KWON YOUNG AH (KR)
KWON SUNG PIL (KR)
JUN HYUN JUNG (US)

PCT/KR2015/000405

July 23, 2015

January 14, 2015

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CHOI WON CHEOL (KR)
KWON YOUNG AH (KR)

G01N33/574; G01N33/48; G01N33/53

WO2012135844A2

2012-10-04

US20100298151A1	2010-11-25
KR20030033134A	2003-05-01
KR20060011817A	2006-02-03
KR2014000393W	2014-01-14
KR2014004197W	2014-05-09
KR20150004287A	2015-01-12
KR20150000119A	2015-01-02
KR20150004288A	2015-01-12

KOSAKA, N. ET AL.: "Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis", CANCER SCIENCE, vol. 101, no. 10, October 2010 (2010-10-01), pages 2087 - 2092, XP055033304
See also references of EP 3096141A4

LEE, Cheo Young et al. (KR)
이처영 (KR)

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