BACKGROUND OF THE INVENTION All references, including any patents or patent applications, cited in this specification are hereby incorporated by reference. No admission is made that any reference constitutes prior art. The discussion of the references states what their authors assert, and the applicants reserve the right to challenge the accuracy and pertinency of the cited documents. It will be clearly understood that, although a number of prior art publications are referred to herein, this reference does not constitute an admission that any of these documents forms part of the common general knowledge in the art, in Australia or in any other country.

Alzheimer's disease is characterised by the presence of distinctive lesions in the patient's brain. These brain lesions include abnormal intracellular filaments, called neurofibrillary tangles, and extracellular deposits of amyloid in senile, or amyloid, plaques. Amyloid deposits are also present in the walls of cerebral blood vessels of Alzheimer's patients. The major constituent of amyloid plaques has been identified as a 4 kilodalton peptide (39-43 residues) called P-amyloid peptide (Ap) (Glenner and Wong, 1984). Diffuse deposits of Ap peptides are frequently observed in normal adult brains, whereas Alzheimer's disease brain tissue is characterised by more compacted, dense-core P-amyloid plaques. These observations suggest that Ap deposition precedes, and contributes to, the destruction of neurons which occurs in Alzheimer's disease. In further support of a direct

pathogenic role for A (3, p-amyloid has been shown to be toxic to mature neurons, both in culture and in vivo (Yanker, 1996).

Natural Ap is derived from proteolysis from a much longer protein, known as the amyloid precursor protein (APP) (Kang et al., 1987). The APP gene maps to chromosome 21, and it is thought that this explains the amyloid deposition which is seen at an early age in individuals with Down's syndrome, which is caused by trisomy of chromosome 21; the pattern of deposition of amyloid in Down's syndrome is similar to that seen in Alzheimer's disease. However, the physiological function of APP has not yet been established.

There are three main isoforms of APP, which respectively contain 695,751 and 770 amino acids (Hardy, 1997). These forms are generally referred to as APP695, APP751 and APP770 respectively. APP undergoes consecutive proteolytic degradation by P-secretase and y-secretase, forming Ap. In contrast, APP degradation within the Ap domain by a-secretase prevents the formation of amyloid, and results in the release of the p3 peptide, consisting of Ap residues 17 to 40 or 17 to 42. Degradation of APP by a-secretase or ß-secretase results in soluble APP fragments, referred to as sAPPa and sAPPß, which represent the APP ectodomains which are released into the extracellular space. This degradation is frequently referred to as"APP processing".

The Ap peptides then undergo aggregation to produce the toxic a-sheet structures found in extracellular deposits in Alzheimer's disease and Down's syndrome.

Recent data suggest that the aggregated peptide has redox properties and can generate reactive oxygen species, which attack enzymes and possibly cell membranes, causing neurotoxicity (Bush, 2000).

APP expression modulates copper homeostasis, since APP-/-mice have elevated copper levels in the liver and cerebral cortex when compared to APP+/+ mice (White et

al., 1999b). In addition, elevated copper concentrations reduce Ap production and increase secretion of APP in a cell-line transfected with human APP cDNA (Borchardt et al., 1999). This effect is modified by zinc, or by zinc and copper chelators (Borchardt et al., 2000). Therefore APP has an important role in modulating cellular copper metabolism in certain tissues, including the brain.

Moreover, neurons expressing wild-type APP (APP+/+) are significantly more sensitive to copper toxicity than are APP-deficient neurons (APP-/-) (White et al,. 1999a), and interaction of APP-Cu (I) species with hydrogen peroxide can result in Cu (I) oxidation to Cu (II) and APP fragmentation (Multhaup et al., 1998). Therefore alterations to APP and/or copper metabolism, such as those found in Alzheimer's disease, could potentially result in increased APP-Cu (I)-mediated generation of reactive oxygen intermediates and increased oxidative stress, as well as altered APP processing to Ap (Borchardt et al., 1999; Cherny et al., 1999). However, copper neurotoxicity mediated by full length APP has not hitherto been directly demonstrated in vivo or in vitro.

Although the fundamental pathology, genetic susceptibility and biology associated with AD are becoming clearer, a rational chemical and structural basis for developing effective drugs to prevent or cure the disease remains elusive. While the genetics of Alzheimer's disease indicate that the metabolism of Ap is intimately associated with the pathogenesis of the disease as indicated above, drugs for the treatment of Alzheimer's disease have so far focused on"cognition enhancers", which do not address the underlying disease processes.

These drugs have met with only limited success. Thus there is a need in the art for additional agents for treatment of Alzheimer's disease.

International Patent Application No. PCT/AU92/00610 by The University of Melbourne shows that chelating agents which have the ability to bind di-or trivalent metal ions

such as Cu2+, Zn2+ or Fe are able to dissolve amyloid deposits from brains of patients with Alzheimer's disease.

The inventors proposed the hypothesis that large metal ions were required in order to induce aggregation of A (3 into amyloid fibrils. These findings have also been used as the basis for assays for candidate pharmaceutical agents for the achievement of Alzheimer's disease; see for example International patent application No.

PCT/US94/11928, PCT/US98/04683, US patent application No.

09/224953, and PCT/US99/05291, all by The General Hospital Corporation, which show that this hypothesis, and related hypotheses regarding the role of reactive oxygen species, has enabled the identification of a number of candidate therapeutic agents. In addition, International patent application No. PCT/US94/11895 by The General Hospital Corporation discloses a diagnostic assay for Alzheimer's disease which is based on the same hypothesis.

Agents which interact with the APP and limit the production of the Ap peptide are therefore particularly desirable. In vitro studies have shown that the interaction between Cu and APP can cause APP fragmentation and decreased APP processing into Ap. The binding of divalent copper leads to the oxidation of two cysteine residues of APP, and in turn to formation of an additional disulphide bond (Multhaup et al., 1998; Borchardt et al., 1999). An understanding of the molecular interaction between Cu and the APP is required for the rational development of agonists capable of limiting the production of the Ap peptide.

Such agonists may have the additional potential to protect cells from damage by blocking Cu (II) binding of APP and thus preventing the formation of reactive axygen species produced by Cu (II) and hydrogen peroxide (Borchardt et al., 1999).

International patent application No. PCT/DE00/00693 by Beyreuther et al. (WO00/51632) shows that APP interacts with divalent zinc and copper ions at two specific sites.

They also showed that copper stimulates increased release of the products of the a-secretory metabolic pathway of APP, sAPPa and p3, and reduced release of the products of the ß-secretory metabolic pathway, p3.5 and Ap.

Beyreuther et al. therefore proposed that compounds which act as copper agonists could reduce or prevent the formation of Ap, and therefore would be useful for treatment or prevention of Alzheimer's disease. However, although functional methods of identifying compounds which could be effective for this purpose are described, there is no information provided regarding the structure of the copper-binding site, and therefore this application provides no rational basis for selecting candidate compounds for testing in the functional assays.

The present inventors have now determined the three- dimensional solution structure of the copper-binding domain of APP. Knowledge of the structure of this binding domain provides a basis for the rational identification of compounds which bind to APP and interfere with amyloidogenic processing of APP. It is envisaged that compounds which mimic the effect of, promote or stabilise the binding of copper to the APP will decrease the processing of APP into Ap, and will reduce the associated APP-Cu (I)-mediated generation of residue oxygen intermediates and will therefore be useful as therapeutic agents.

SUMMARY OF THE INVENTION In a first aspect the invention provides a method of identifying a compound which is capable of acting as an agonist of binding of divalent copper ions to APP, comprising the step of identifying a compound which has a conformation and polarity such that it interacts with an amino acid residue in APP selected from the group consisting of:

a) His147, His151, Tyrl68 and Metl70 ; b) Leul36, Glnl38, Glu139, Argl40, Metl41, Vall43, Glu145, His149, Trpl50, Vall53, Alal54, Thrl57, Argl80, lyl81, Vall82 and Phel84; and c) His147, His151, Tyrl68, Metl70, Alal54, Trpl50, Lysl55, Leul65, Glyl69, Phel79, Vall82, Glu183 and Phel84.

The regions encompassing the groups of amino acid residues listed here as a), b) and c) are referred to herein as the first, second and third copper-binding sites respectively. Collectively these regions form part of the copper-binding domain of APP. Without wishing to be limited by any proposed mechanism, we believe that region (a) is the principal site to which copper atoms bind.

Preferably a compound identified by this step is then subjected to in vitro and/or in vivo testing for ability to act as an agonist of binding of divalent copper to APP, and for the ability to inhibit the production of Ap from APP.

Preferably the compound has the ability to interact with the copper-binding domain of APP in such a way that the extent of processing of APP to Ap or to Ap-containing fragments in the presence of the compound is reduced, compared to that of APP in the absence of the compound.

Preferably the compound binds to at least two, more preferably at least three, and even more preferably four of the amino acids identified above.

Even more preferably the compound has the ability to penetrate the blood-brain barrier.

It will be clearly understood that the term "identifying"encompasses either designing a new compound, or selecting a compound from a group or library of previously known compounds.

The term"agonist"refers to: a) a compound which has a conformation and polarity such that the compound itself binds to the copper-binding site of APP;

b) a compound which has a conformation and polarity such that the compound binds to the copper-binding domain of APP at a site other than the copper-binding site, and this enhances or stabilises the binding of copper ions to the copper-binding site; or c) a compound which has a conformation and polarity such that the compound binds to APP at a site other than the copper-binding site, in which the binding has no effect on copper binding but induces an effect the same as or similar to one which is induced by binding of copper to the copper-binding site.

It will be appreciated that a compound may have more than one of these abilities.

Preferably when the compound has the effect of stabilising binding of copper to the copper-binding domain, the compound stabilises the oxidation state of the copper, thus inhibiting production of toxic Cu (I) ions.

The expression"an effect the same as or similar to one which is induced by binding of copper to the copper- binding site"is to be understood to include effects such as reducing the production of Ap from APP or induction of dimerization of APP. The skilled person will be aware of suitable techniques for determining whether a compound has one or more such effects.

In one preferred embodiment, the compound interacts directly with the copper-binding site, ie. with one or more amino acids selected from the group consisting of His147, His151, Tyrl68 and Metl70.

It is contemplated that in this embodiment the compound will be a metal complex which can bind to the imidazole moiety of a histidine residue.

Metal ions capable of binding to the imidazole nitrogen (s) of histidine include Mn, Fe, Co, Ni, Cu, Zn, Ru, Pd, Ag, Cd, Pt, Au, Rh and Hg. Complexes of these metals would be expected to be predominantly four- coordinate tetrahedral or distorted tetrahedral/square planar complexes, five-coordinate complexes with either a

trigonal bipyramid or square pyramid configuration, or six-coordinate octahedral or distorted octahedral complexes.

In a second aspect the invention provides a computer-assisted method for identifying compounds potentially able to bind to the copper-binding domain of the APP and decrease the processing of the APP into Ap or Ap containing fragments, using a programmed computer comprising the steps of: (a) inputting into the programmed computer data comprising the atomic coordinates of the APP copper- binding domain, as shown in Appendix A, corresponding to the binding site defined by amino acid residues (i) His147, His151 and Tyrl68 and Metl70 (ii) Leul36, Glnl38, Glul39, Argl40, Metl41, Vall43, Glu145, His149, Trpl50, Vall53, Alal54, Thrl57, Argl80, Glyl81, Vall82 and Phel84, or (iii) Hisl47, His151, Tyrl68, Metl70, Alal54, Trpl50, Lysl55, Leul65, Glyl69, Phel79, Vall82, Glu183 and Phel84 or a subset thereof; (b) generating, using computer methods, a set of atomic coordinates of a structure that possesses stereochemical complementarity to the atomic coordinates defined in (a) or a subset thereof, thereby generating a criteria data set; (c) comparing, using the processor, the criteria data set to a computer database of chemical structures; (d) selecting from the database, using computer methods, chemical structures which are similar to a portion of said criteria data set; and (e) outputting the selected chemical structures which are similar to a portion of the criteria data set.

Preferably the method further comprises the step of obtaining a compound with a chemical structure selected in steps (d) and (e), and testing the compound for the

ability to decrease processing of the APP into Ap or Ap- containing fragments.

In a third aspect the invention provides a computer or a software component thereof for producing a three- dimensional representation of a molecule or molecular complex, which comprises a three-dimensional representation of a homologue of the molecule or molecular complex, in which the homologue comprises a domain that has a root mean square deviation from the backbone atoms of the amino acids of not more than 1.5A, in which the computer comprises: (a) a machine-readable data storage medium comprising a data storage material encoded with machine- readable data, wherein the data comprises the structure coordinates, as shown in Appendix A, of: (i) His147, His151 and Tyrl68 and Metl70 (ii) Leul36, Glnl38, Glu139, Argl40, Metl41, Vall43, Glu145, His149, Trpl50, Vall53, Alal54, Thrl57, Argl80, Glyl81, Vall82 and Phel84, or (iii) Hisl47, His151, Tyrl68, Metl70, Alal54, Trpl50, Lysl55, Leul65, Glyl69, Phel79, Vall82, Glu183 and Phel84 ; (b) a working memory for storing instructions for processing the machine-readable data; (c) a central-processing unit coupled to the working memory and to the machine-readable data storage medium for processing the machine-readable data into the three-dimensional representation ; and (d) a display coupled to the central-processing unit for displaying the three-dimensional representation.

In one class of embodiments, the three-dimensional representation is of a molecule or molecular complex defined by the set of structure coordinates set out in Appendix A, or wherein the three-dimensional representation is of a homologue of the molecule or molecular complex, the homologue having a root mean square

deviation from the backbone atoms of the amino acids of not more than 1.5A.

An additional aspect of the invention provides a computer or a software component thereof for determining at least a portion of the structure coordinates corresponding to a three-dimensional structure of a molecule or molecular complex, in which the computer comprises: (a) a machine-readable data storage medium comprising a data storage material encoded with machine- readable data, in which the data comprises at least a portion of the structural coordinates according to Appendix A; (b) a machine-readable data storage medium comprising a data storage material encoded with machine- readable data, wherein the data comprise NMR spectral data of the molecule or molecular complex; (c) a working memory for storing instructions for processing the machine-readable data of (a) and (b); (d) a central-processing unit coupled to the working memory and to the machine-readable data storage medium of (a) and (b) for performing a transformation of the machine readable data of (a) and for processing the machine-readable data of (b) into structure coordinates; and (e) a display coupled to the central-processing unit for displaying the structure coordinates of the molecule or molecular complex.

In a fourth aspect the invention provides a compound able to act as an agonist of the binding of copper to the copper-binding domain of APP, wherein the compound is identified by a method according to the invention.

It will be clearly understood that pharmaceutically acceptable salts, derivatives and esters of these compounds are also within the scope of the invention.

In a fifth aspect the invention provides a composition comprising a compound according to the

invention, together with a pharmaceutically-acceptable carrier. It will be appreciated that the composition may comprise two or more compounds according to the invention.

In a sixth aspect the invention provides a method of reducing the processing of the APP into Ap or Ap-containing fragments, comprising the step of exposing the APP to a compound which acts as an agonist for the binding of divalent copper to the copper-binding domain of APP.

In a seventh aspect the invention provides a method of reducing the amyloidogenic processing of APP, comprising the steps of exposing APP to a compound which acts as an agonist of the binding of divalent copper to the copper-binding domain of APP.

In an eighth aspect the invention provides a method of treating Alzheimer's disease or other amyloid-related condition, the method comprising administering to a subject in need thereof a composition according to the invention.

In one preferred embodiment of the invention, the compound is conjugated to a targeting moiety.

The term"targeting moiety"as used herein refers to a functional group which is covalently linked to a targeting moiety which will specifically bind to or associate with the APP. Suitable targeting moieties include, but are not limited to, polypeptides, nucleic acids, carbohydrates, lipids, APP ligands, antibodies and the like. In a preferred embodiment the targeting moiety has a hydrophobic region which interacts with the APP.

For example, the targeting moiety may include a fatty acid molecule.

In a particularly preferred embodiment, the ligand- targeting moiety complex is able to pass through the blood-brain barrier.

Preferably in each of the fourth to eighth aspects the compound has a conformation and polarity such that it binds to at least one, preferably at least two, more

preferably at least three, and most preferably four amino acid residues in APP selected from the group consisting of: a) His147, His151 and Tyrl68 and Metl70 ; b) Leul36, Glnl38, Glu139, Argl40, Metl41, Vall43, Glu145, His149, Trpl50, Vall53, Alal54, Thrl57, Argl80, Glyl81, Vall82 and Phel84 ; and c) His147, His151, Tyrl68, Metl70, Alal54, Trpl50, Lysl55, Leul65, Glyl69, Phel79, Vall82, Glu183 and Phel84.

It is preferred that the compound has a high affinity for the selected target site. For in silico screening using computer modelling systems, the affinity constant is preferably < lmM, more preferably < lnM. For in vitro binding as assessed by NMR, the affinity constant is preferably < lnM.

The compounds of the invention may be formulated into pharmaceutical compositions, and administered in therapeutically effective doses. By"therapeutically effective dose"is meant a dose which results in the inhibition of the processing of APP into A (3 or Ap-containing fragments. The appropriate dose will be ascertainable by one skilled in the art using known techniques.

The pharmaceutical compositions may be administered in a number of ways, including, but not limited to, orally, subcutaneously, intravenously, intraperitoneally and intranasally.

The dosage to be used will depend on the nature and severity of the condition to be treated, and will be at the discretion of the attending physician or veterinarian. The most suitable dosage for a specific condition can be determined using normal clinical trial procedures.

While it is particularly contemplated that the compounds of the invention are suitable for use in medical treatment of humans, they are also applicable to

veterinary treatment, including treatment of companion animals such as dogs and cats, and domestic animals such as horses, cattle and sheep, or zoo animals such as felids, canids, bovids, and ungulates.

Methods and pharmaceutical carriers for preparation of pharmaceutical compositions are well known in the art, as set out in textbooks such as Remington's Pharmaceutical Sciences, 19th Edition, Mack Publishing Company, Easton, Pennsylvania, USA.

The compounds and compositions of the invention may be administered by any suitable route, and the person skilled in the art will readily be able to determine the most suitable route and dose for the condition to be treated. Dosage will be at the discretion of the attendant physician or veterinarian, and will depend on the nature and state of the condition to be treated, the age and general state of health of the subject to be treated, the route of administration, and any previous treatment which may have been administered.

The carrier or diluent, and other excipients, will depend on the route of administration, and again the person skilled in the art will readily be able to determine the most suitable formulation for each particular case.

Amyloid deposition has also been implicated in the pathogenesis of the neurodegenerative disease, such as Parkinson's disease, amyotrophic lateral sclerosis, and cataract. Thus, while the invention is described in detail in relation to Alzheimer's disease, it is also applicable to amyotrophic lateral sclerosis, motoneuron disease, cataract, Parkinson's disease, Creutzfeldt-Jacob disease, Hungington's disease, dementia with Lewy body formation, multiple system atrophy, Hallerboden-Spatz disease, and diffuse Lewy body disease, or cataracts.

Throughout this specification the word"comprise", or variations such as"comprises"or"comprising", will be understood to imply the inclusion of a stated element,

integer or step, or group of elements, integers or steps, but not the exclusion of any other element, integer or step, or group of elements, integers or steps.

BRIEF DESCRIPTION OF THE FIGURES Figure 1 is a schematic representation of APP, showing important regions of the molecule. The N-terminal growth factor domain is followed by the copper-binding domain (CuBD), an acidic region, Kunitz-type protease inhibitor and Ox-2 domains which occur in some APP isoforms, a series of domains known to bind carbohydrate, a transmembrane (TM) region, and a cytoplasmic tail. The location of the Ap region, a major component of Alzheimer's disease plaques, is also shown. The sequence of the CuBD is shown, with the copper-binding amino acid residues in large bold type, and the cysteine residues which are involved in disulphide bridges shown in underlined bold type.

Figure 2 shows the solution structure of APP124-189. a. Stereoview of the backbone (N, Ca, C) traces of the 21 lowest energy structures for APP124-189 superimposed over backbone atoms (N, Ca, C) of residues 128-189. b. A ribbon depiction of the NMR structure closest to the geometric average of APP124-189. c. Surface characterization of APP124-189.

Electrostatic molecular surface rendering of the NMR structure closest to the geometric average of APP124-189.

Surfaces are shaded to indicate electrostatic charge, with regions with electrostatic potential <-8 kgT light grey and those > +8 kgT dark grey (kg, Boltzmann constant, T, absolute temperature).

Figure 3 shows NMR spectra of APP124-189, illustrating the effects of addition of metal ions. a. The top spectrum is a 600 MHz 1H spectrum of unlabelled APP124-189 ; the bottom spectrum is after the addition of Zn2+. Peaks due to the S-methyl Hs of Metl70,

H52 of His151 and the Hb1 and Hsl of Tyrl68 that are visible in the top spectrum disappear from the bottom spectrum upon the addition of Zn2+ have been labelled. b. [1H, 15N] HSQC spectra of 3,, 9N-labeled APP124-189 before (spectrum on the left) and after (spectrum on the right) the addition of one equivalent of Cu2+. c. Changes in the [1H, 15N] HSQC spectrum upon addition of Cu2+ are mapped on to the surface of APP124- 189, unaffected residues are shown in dark grey, while those residues whose backbone amides were perturbed by the presence of Cu2+ are shown in light grey. d. A region of the [1H, 13C] HSQC spectra of 15N, 3C-labeled APP124-189 where the S-methyl He and Ce resonances of the methionine residues are visible. The top spectrum shows the S-methyl He and CE resonances of 141 on the left and 170 on the right. The middle spectrum shows that the effect of adding one equivalent of Cu2+is the disappearance of the peak due to Metl70. The bottom spectrum shows that a new peak is visible in the region of the [1H, 13C] spectrum associated with the S-methyl of methionine, after APP124-189 has incubated with Cu2+ for 48 hours.

Figure 4 shows orthogonal views of the putative metal binding site, residues His147, His151, Tyrl68 and Metl70. These views show that the orientation of the residues is such that the configuration around any metal bound in this site is tetrahedral, and that the binding site is a surface exposed site.

Figure 5 shows a model of a metal ion in a tetrahedral configuration bound to His147, His151, Tyrl68 and Metl70 of APP124-189.

Figure 6 shows docking of (2,5-dimethyl-phenyl)- carbamic acid napthalen-2-yl ester (Compound 42613) to the principal copper-binding site of APP, encompassing residues Hisl47, His151, Tyrl68 and Metl70, as demonstrated in an in silico modelling system.

Figure 7 shows docking of 3- (4-Iodo-phenyl)-l- phenyl-imidazo [1-5-a] pyridine (Compound 21056) to the secondary copper-binding site of APP which is located at the back the copper-binding domain and encompasses the residues listed in (b) above, as demonstrated in an in silico modelling system.

DETAILED DESCRIPTION OF THE INVENTION The general structure of APP is illustrated schematically in Figure 1, which shows the important regions of the molecule. It can be seen that the copper- binding domain is near the N-terminal of the molecule, whereas the region which gives rise to Ap is close to the C-terminal. The sequence APP124-189 from the copper- binding domain was selected by analysis of the crystal structure of the growth factor domain and sequencing of the C-terminal region.

The derivation of the CuBD construct, APP124-189, was based upon our previous work, in which we solved the structure of APP28-123 (Rossjohn et al., 1999). Those studies defined the C-terminal end of the first APP domain, also called the growth factor domain, as residue 123. Therefore the start of the second domain, CuBD, commenced at residue 124. The C-terminal end of the CuBD was chosen as residue 189. This corresponded to the end of the putative zinc binding site (Bush et al., 1993).

APP133-189 corresponds to a truncated version of the CuBD. Based on our copper-binding studies using NMR, the free N-terminus was involved in artefactual copper- binding. This free N-terminus is not present in physiologically expressed APP. To remove the influence of this artefactual Cu binding site, APP133-189 was generated. Furthermore, residues 124-132 were predominantly unstructured and this may have prevented crystal formation; in fact we have found that APP133-189 readily forms crystals as a result of removal of these

residues. The APP133-189 will be valuable for future crystallisation structure studies.

Previous studies by Multhaup and colleagues proposed that the reduction of Cu (II) by the CuBD results in the formation of an intramolecular disulphide bond between cysteines 144-158 (Multhaup et al., 1998). The results presented herein indicate an alternative mechanism, whereby the reduction of Cu (II) to Cu (I) does not require the formation of an intramolecular disulphide bond between cysteines 144-158. We have found that although the APP124-189 protein has no free cysteines, it is able to reduce Cu (II) to Cu (I). Our structure proposes that methionine is a suitable substrate to be oxidised in order for Cu (II) to be reduced. The NMR structure reported here for the first time has properly defined the copper-binding site beyond the histidine residues at 147,149 and 151 proposed by Multhaup and colleagues (see below).

In vitro studies have shown that the interaction between Cu and APP can cause APP fragmentation and decreased APP processing into AD. In order to define the interaction between copper and the APP at the molecular level, the inventors have solved the NMR structure of the APP copper-binding domain (APP residues 124-189). The co- ordinates for this structure are provided in Appendix A.

The primary observation was that the binding of copper to the copper-binding site of APP, which leads to processing of APP to Ap, occurs at a site near the surface of the molecule. Modulation of this binding could occur via three possible mechanisms. Firstly, an agonist molecule could exert its action via direct binding to the copper-binding site; alternatively, the agonist could bind to a"secondary shell", which in turn perturbs the copper- binding domain. A third alternative is that the agonist binds to a separate site more distantly located on the APP molecule.

The three-dimensional structure of APP124-189 has three disulfide bonds, and consists of an a-helix

overlying a triple-stranded 0-sheet. The surface is highly charged, with several areas of high negative and positive potential. On the surface of the molecule there are two basic patches but no extensive hydrophobic area.

The metal-binding properties of APP124-189 to Zn (Gly) 2 Ni (Gly) 22+ and Cu (Gly) 22+ showed resonance changes in His147, His151 and Tyrl68. The side-chains of these residues, together with Metl70, are orientated so that they form a favourable metal binding site. Very small movements in their side-chains are required for metal binding to occur in a tetrahedral fashion. No previous examples of coordination spheres incorporating both methionine and tyrosine could be identified in the literature, indicating that the APP CuBD utilizes a novel Cu-binding site.

This information provides a rational basis for the development of compounds which mimic Cu2+, ie. which inhibit processing of the APP into Ap or Ap-containing fragments. Accordingly, these compounds are likely to have therapeutic value in the treatment of diseases such as Alzheimer's disease.

The general principles of drug design, which are discussed below, can be applied by persons skilled in the art to produce compounds which preferably bind to the copper-binding site defined by the His147, His151 and Tyrl68 and Metl70 residues of the APP and inhibit the processing of APP into the Ap peptide.

The inventors have also identified two additional regions on the copper-binding domain of the APP, which are thought to be involved in interactions which enhance or stabilise the binding of copper to the copper-binding site.

The first of these regions, region (b), is located on the back of the copper-binding domain of APP ie. on the opposite side to the copper-binding site, and encompasses residues Leul36, Glnl38, Glul39, Argl40, Metl41, Vall43,

Glu145, His149, Trpl50, Vall53, Alal54, Thrl57, Argl80, Glyl81, Vall82 and Phel84.

The second of these regions, region (c), is located on the same side of APP as the copper-binding site, and encompasses residues Hisl47, His151, Tyrl68, Metl70, Alal54, Trpl50, Lysl55, Leul65, Glyl69, Phel79, Vall82, Glu183 and Phel84.

It is envisaged that the binding of ligands to these regions may enhance, stabilise or mimic the binding of copper to the copper-binding site of APP, thereby reducing amyloidogenic processing of APP.

The preferential binding of ligands to the copper- binding site or other sites on the copper-binding domain of APP, preferably with an affinity in the order of 10-8M or better, may arise from enhanced stereochemical complementarity relative to naturally-occurring ligands.

Pursuant to the present invention, such stereochemical complementarity is characteristic of a molecule which matches intra-site surface residues lining the groove of the first copper-binding site (eg. His147, His151 and Tyrl68 and Metl70) or other binding region identified herein. By"match"we mean that the identified portions interact with the surface residues, for example, via hydrogen bonding or by entropy-reducing van der Waals interactions which promote desolvation of the biologically active compound within the site, in such a way that retention of the biologically active compound within the groove is energetically favoured.

It will be appreciated that it is not necessary that the complementarity between ligands and the copper-binding site extend over all residues lining the groove in order to stabilise binding of the natural ligand. Accordingly, ligands which bind to some, but not all, of the residues lining the groove are encompassed by the present invention.

In general, the design of a molecule possessing stereochemical complementarity can be accomplished by

means of techniques which optimize, either chemically or geometrically, the"fit"between a molecule and a target receptor. Suitable such techniques are known in the art.

(See Sheridan and Venkataraghavan, 1987; Goodford 1984; Beddell 1985; Hol, 1986; and Verlinde 1994, the respective contents of which are hereby incorporated by reference.

See also Blundell 1987).

Thus there are two preferred approaches to designing a molecule according to the present invention, which complements the shape of the copper-binding site. In the first of these, the geometric approach, the number of internal degrees of freedom, and the corresponding local minima in the molecular conformation space, is reduced by considering only the geometric (hard-sphere) interactions of two rigid bodies, where one body (the active site) contains"pockets"or"grooves"which form binding sites for the second body (the complementing molecule, as ligand). The second approach entails an assessment of the interaction of different chemical groups ("probes") with the active site at sample positions within and around the site, resulting in an array of energy values from which three-dimensional contour surfaces at selected energy levels can be generated.

The geometric approach is illustrated by Kuntz et al. (1982), the contents of which are hereby incorporated by reference, whose algorithm for ligand design is implemented in a commercial software package distributed by the Regents of the University of California and further described in a document, provided by the distributor, entitled"Overview of the DOCK Package, Version 1.0,", the contents of which are hereby incorporated by reference.

Pursuant to the Kuntz algorithm, the shape of the cavity represented by the copper-binding site is defined as a series of overlapping spheres of different radii. One or more extant databases of crystallographic data, such as the Cambridge Structural Database System maintained by Cambridge University (University Chemical Laboratory,

Lensfield Road, Cambridge CB2 1EW, U. K.) and the Protein Data Bank maintained by Brookhaven National Laboratory (Chemistry Dept. Upton, NY 11973, U. S. A.), is then searched for molecules which approximate the shape thus defined.

Molecules identified in this way, on the basis of geometric parameters, can then be modified to satisfy criteria associated with chemical complementarity, such as hydrogen bonding, ionic interactions and van der Waals interactions.

The chemical-probe approach to ligand design is described, for example, by Goodford (1985), the contents of which are hereby incorporated by reference, and is implemented in several commercial software packages, such as GRID (product of Molecular Discovery Ltd., West Way House, Elms Parade, Oxford OX2 9LL, U. K.). Pursuant to this approach, the chemical prerequisites for a site- complementing molecule are identified at the outset, by probing the copper-binding site with different chemical probes, e. g., water, a methyl group, an amine nitrogen, a carboxyl oxygen, and a hydroxyl. Favoured sites for interaction between the active site and each probe are thus determined, and from the resulting three-dimensional pattern of such sites a putative complementary molecule can be generated.

Programs suitable for searching three-dimensional databases to identify molecules bearing a desired pharmacophore include: MACCS-3D and ISIS/3D (Molecular Design Ltd., San Leandro, CA), ChemDBS-3D (Chemical Design Ltd., Oxford, U. K.), and Sybyl/3DB Unity (Tripos Associates, St. Louis, MO).

Programs suitable for pharmacophore selection and design include: DISCO (Abbott Laboratories, Abbott Park, IL), Catalyst (Bio-CAD Corp., Mountain View, CA), and ChemDBS-3D (Chemical Design Ltd., Oxford, U. K.).

Databases of chemical structures are available from a number of sources including Cambridge Crystallographic

Data Centre (Cambridge, U. K.) and Chemical Abstracts Service (Columbus, OH).

De novo design programs include Ludi (Biosym Technologies Inc., San Diego, CA), Sybyl (Tripos Associates) and Aladdin (Daylight Chemical Information Systems, Irvine, CA).

Those skilled in the art will recognize that the design of a mimetic compound may require slight structural alteration or adjustment of a chemical structure designed or identified using the methods of the invention.

This aspect of the invention may be implemented in hardware or software, or a combination of both. However, the invention is preferably implemented in computer programs executing on programmable computers each comprising a processor, a data storage system (including volatile and non-volatile memory and/or storage elements), at least one input device, and at least one output device.

Program code is applied to input data to perform the functions described above and generate output information.

The output information is applied to one or more output devices, in known fashion. The computer may be, for example, a personal computer, microcomputer, or workstation of conventional design.

Each program is preferably implemented in a high level procedural or object-oriented programming language to communicate with a computer system. However, the programs can be implemented in assembly or machine language, if desired. In any case, the language may be compiled or interpreted language.

Each such computer program is preferably stored on a storage medium or device (e. g., ROM or magnetic diskette) readable by a general or special purpose programmable computer, for configuring and operating the computer when the storage media or device is read by the computer to perform the procedures described herein. The inventive system may also be considered to be implemented as a computer-readable storage medium, configured with a

computer program, where the storage medium so configured causes a computer to operate in a specific and predefined manner to perform the functions described herein.

It is contemplated, without wishing to limit the invention, that a suitable compound may be a metal complex that can exchange or bind functional moieties such as histidine. Preferably the metal complex is capable of binding between 1 and 4, more preferably 3 or 4 of the amino acid residues Hisl47, His151, Tyrl68 and Metl70 of the copper-binding domain of amyloid precursor protein.

Metal ions capable of binding to the imidazole nitrogen (s) of histidine include Mn, Fe, Co, Ni, Cu, Zn, Ru, Pd, Ag, Cd, Pt, Au, Rh and Hg. Complexes of these metals would be expectecd to be predominantly four coordinate tetrahedral (distorted tetrahedral)/square planar complexes, five coordinate complexes with either a trigonal pyramid or square pyramid configuration or six coordinate octahedral (or distorted octahedral) complexes.

Compounds identified by the methods of the present invention may be assessed by a number of in vitro and in vivo assays. For example, the identification of ligands which bind to the copper-binding site may be undertaken using a solid-phase receptor binding assay. Ligands can be screened in a cell-based assay by measuring their effect on APP processing and Ap production. Binding affinity for candidate ligands may be measured using biosensor technology.

Assays to determine the binding of metal complexes to APP may be performed by NMR and W-Visible spectroscopy and ESR for paramagnetic metals. Assays are available for measuring Cu/Fe reduction, hydrogen peroxide generation, hydroxyl radical generation, and carbonyl generation, all of which assess the redox capacity of APP in the presence of Cu and Fe.

The invention is further described below in detail with reference to the following, non-limiting examples.

Example 1: Expression and purification of recombinant APP124-189 and APP133-189.

The sequence encoding APP124-189 (SEQ ID NO : 1) was amplified by PCR using the primers GCT CGA GAA AA GAG AGG CTA GTG ATG CCC TTC TCG (primer 1; SEQ ID NO : 2) and GAA TTC TTA CAG TGG GCA ACA CAC AAA CTC (primer 2; SEQ ID NO : 3).

The PCR product was cloned as a XhoI-EcoRI fragment into the Pichia pastoris vector pIC9 (Invitrogen) and then transformed into P. pastoris strain GS115 as previously described (Henry et al., 1997). Expressing clones were identified by analysing the culture supernatants by silver stain-SDS-PAGE.

APP 124-189, whose structure is shown schematically in Figure 1, was expressed as a secreted protein in the yeast Pichia pastoris and purified by a two-step purification scheme to homogeneity, as judged by mass spectroscopy and N-terminal sequencing.

Isotopically-labelled protein was prepared by the protocol of Laroche et al (Laroche et al., 1994). 15N- single labelled APP124-189 was produced using FM22 basic medium, which contains 5 g 15NH4Cl as the sole nitrogen source. A five ml overnight culture was inoculated into 400 ml growth medium (FM22 basic, 0.5%-glucose, 0.1% PTM1 salts, 0.06M KOH). After 48 h the cells were collected by centrifugation and resuspended into induction medium (FM22 basic medium, 0.5% methanol, 0.1% PTM1 salts) and shaken for 48 hr. The 13C, l5N-double labelled APP124-189 was expressed as described above, except that the induction medium was FM22 basic medium, 0.5% 13C-methanol, 0.1% PTM1 salts. After 24 hr another 0.5% 13C-methanol was added, and then the culture was shaken for a further 24 hr. The cells were pelleted by centrifugation and the supernatant kept for protein purification.

APP124-189 was purified to homogeneity in two steps.

The supernatant was concentrated, and the buffer was

exchanged into 20 mM TRIS buffer pH 8.5 containing 5 mM EDTA, and then applied to a QHyperD 1.6 x 13 cm column (Biosepra, France), equilibrated in the same buffer. The APP124-189 protein was eluted in the column flow-through, then concentrated and then applied to a Superdex 75 HR 10/30 gel filtration column (Amersham-Pharmacia, Australia) in 20 mM sodium phosphate buffer pH 6.8 containing 1 mM EDTA. The APP124-189 eluted as a single peak with a molecular weight of-11 kDa. N-terminal amino acid sequencing and mass spectrometery (MALDI-TOF) analysis confirmed that the N-terminus was intact, and that the mass correlated to the predicted sequence. The APP124-189 protein was concentrated by ultrafiltration to a final concentration of 5 mg/ml in 20mM phosphate pH 6.8 buffer.

APP133-189 was expressed and purified in the same way as for APP129-189.

Example 2: NMR spectroscopy and spectral assignments.

NMR spectra were acquired at 30°C using a Bruker DRX-600 spectrometer equipped with triple-resonance pulsed-field gradient probes. Sequential resonance assignments were made using a series of triple resonance spectra (Sattler et al., 1999) acquired on either uniformly 15N-or 13C, 15N-labelled APP124-189 using the methods described by Day et al. (1999). Spectra were obtained on samples which typically contained 0.5 mM protein in 50 mM phosphate buffer (pH 6.9) at 30°C, and 1 mM EDTA, which was either removed or titrated out in the metal-binding studies. APP124-189 had good solution properties at pH 6.9, and was stable for months in the presence of EDTA at 0.5 mM.

Inductively-coupled plasma mass spectrometry analysis revealed that APP124-189 had very low levels of bound metal, suggesting that it was in the apo form. An essentially complete set of resonance assignments was determined from spectra acquired using 15N and 13C, 15N-

labelled protein. 15N resonances were not observed for Aspl25 and Ilel76. Ten hydrogen bond restraints were also employed along the helix. There are six cysteine residues within this domain, and these form three disulfide bonds.

An Ellman's test confirmed that there were no free thiols present, and chemical methods had previously determined the disulfide pairings to be 133-186/187,158-186/187 and 144-174. Klaus et al. (1993) have shown that CìaH/CjßH and CißH/CjßH NOEs have a positive predictive value for a disulfide pairing between half-cystines i and j.

CiaH/CjßH and CiDH/CjßH NOEs were observed between residues 133 and 187 as well as between 158 and 186, and as a result of this the structure of APP124-189 was determined with the 133-187,158-186 and 144-174 disulfide pairings (1-6,3-5,2-4). The structures were calculated using the methods reported by Day et al. (1999). The final 21 structures, depicted in Figure 2a, were selected on the basis of their stereochemical energies, and structural statistics are presented in Table 1.

TABLE 1 Structural Statistics for the 21 Energy-Minimised Structures of APP124-189 from CNS. a Total distance constraints 1233 Sequential () i-jt = 1) 321 Short-range (1 < li-je < 5) 229 Long-range (|i-j| # 5) 532 Intra-residue 151 Hydrogen bondsa 10 Total angle constraints 111 59 v 21 XI 31 RMS deviations from experimental distance restraints A (1241) b 0. 0216 # 0.0009 RMS deviations from experimental dihedral restraints (deg) (109) b 0.83 + 0.05 RMS deviations from idealised geometry bonds (A) 0.004 + 0.00009 angles (deg) 0.50 i 0.02 impropers (deg) 0.41 i 0.02 Mean pairwise RMSD (A) Backbone heavy atoms All heavy atoms Residues 127-189 0.43 i 0.16 1.13 i 0.13 Residues 133-139,147-159,0.17 t O. 05 0. 78 4 0. 11 162-167,181-188 a The best 21 structures after energy minimisation using the program CNS (Brunger et al., 1998). b The numbers of restraints are shown in parentheses. None of the structures had distance violations > 0.2 A or dihedral angle violations > 5°.

The structures are well ordered, with only the three N-terminal residues unstructured (angular order parameter < 0.9), and they have good stereochemical properties, with over 98% of backbone angles falling in the allowed regions

of the Ramachandran plot. {1H} 15N heteronuclear NOE data (data not shown) indicate that, with the exception of residues near the N-terminus, the molecule is rigid along the entire sequence. The pairwise root mean square deviation (RMSD) for the ordered residues (127-189) is 0.43 0.16 over the backbone atoms (N, ca, C), and 0.17 0.05 for the residues involved in secondary structure elements.

The three-dimensional structure of APP124-189, shown in Figure lb, consists of an a-helix (residues 147-159) overlying a triple stranded ß-sheet (residues 133-139, 162-167 and 181-188). Residues 133-139 constitute the first strand of the p-sheet, residues 181-189 the second strand, and residues 162-167 the third strand. The disulfide bond between Cysl33-Cysl87 links the first two strands of the p-sheet, while the 158-186 bond links the a-helix to the middle strand of the P-sheet. The 144-174 disulfide bond connects two loops: Cysl44 is in the loop between the first strand of the P-sheet and the a-helix, while Cysl74 is in the loop which connects the second and third strands of the P-sheet.

There are very few buried hydrophobic residues in the vicinity of this disulfide bond, which is therefore probably very important in stabilising the structure in a region which does not have any secondary structure. In addition to the three disulfide bonds there is a small hydrophobic core which assists in stabilising the structure ; this core consists of small segments of residues from each of the secondary structure elements, Leul36, Trpl50, Vall53, Alal54, Leul65, Metl70, Vall82 and Vall85. Leul72 has a positive angle, as determined by the presence of a large intraresidue NH to CaH NOE and weak (i+1) NOE (Ludvigsen & Poulsen (1992).

As illustrated in Figure lc, the surface of APP124- 189 is highly charged, with several areas of high negative and positive potential. There is a basic patch on each of the two faces of the protein. One patch consists of residues Lysl32, Lysl34, Lysl61, and on the opposite side

of the molecule one face of the helix, Hisl47, His151 and Lysl55, also gives rise to a basic patch. Acidic regions Glu156, Glu160 on one face and Glu183, Aspl67, Aspl31 on the opposite are smaller. There is no extensive hydrophobic area on the surface of APP124-189.

Mass spectrometry revealed that the purified protein was essentially free of metal ions, confirming that it was in the apo form. Titration of Cu (II) into a solution of CuBD resulted in the broadening of some resonances in the NMR spectrum, as would be expected for resonances close to a paramagnetic centre such as Cu (II). Analysis of the pattern of peaks in the 2D [1H, l5N] HSQC spectrum that were broadened by Cu (II), as shown in Figure 3a, suggested the presence of two binding sites, one centred on His147, His151, Tyrl68 and Metl70 and the other involving the N- terminus. The copper-binding site at the N-terminus is not physiologically relevant, since in the intact protein the N-terminus is connected to the growth factor domain (see Figure 1). There was a general decrease in the signal-to-noise ratio of the spectrum following Cu (II) addition, suggesting that higher order aggregates were being formed. To further characterize the metal binding site, the diamagnetic ions Zn (II) and Ni (II) were each titrated into CuBD solutions; similar changes in the NMR spectra were observed with either metal. Decreases in signal-to-noise consistent with metal ion-induced aggregation were observed with Zn (II) addition, leading to a visible precipitate. Resonances corresponding to the aromatic protons of Tyrl68 broadened and disappeared, as did C8H3 protons of Metl70 (Figure 3b). The backbone amide resonances from Hisl47, His151 and Tyrl68 in the 2D [1H, N] HSQC spectrum broadened beyond detection on addition of excess metal ion.

The broadening of resonances upon addition of metal ions is evidence for chemical exchange between the metal bound and apo forms of the protein at an intermediate rate, which implies a Kd in the micromolar range. The

lack of change in resonances distant from the immediate metal binding sites indicated that there was no significant structural alteration upon metal binding. To demonstrate a role for Metl70 in the binding and reduction of Cu (II), changes in the 2D [1H, 13C] HSQC spectrum of CuBD upon addition of Cu (II) were monitored, with the 1H and 13C chemical shifts of the C8H3 and CE of methionine being diagnostic. Initially, the S-methyl resonance of Metl70 broadened beyond detection, whereas the resonance of Metl41, the only other methionine in CuBD, was unaffected. After incubating the sample at 30°C for 48 hr a new resonance was observed, with 1H and 13C chemical shifts typical of CSH3 and C'from methionine, indicating the presence of a modified Metl70, as shown in Figure 3c.

Examination of the structure around the residues whose NMR chemical shifts were affected by the binding of metals shows that residues Hisl47, H149, Tyrl68 and Metl70 are clustered together in the three-dimensional structure so that the side-chains of these residues are presented in a way that would be favourable for metal binding. This is illustrated in Figure 4. The structural orientation of these residues shows that very small movements of the side-chains of these four residues are all that is required before they could bind a metal in a tetrahedral fashion, as shown in Figure 5.

A search of the protein data base did not find any similar coordination spheres for M2+, although peptidylglycine monoxygenase (PDB accession number lphm) contains a surface-available redox-active Cu2+ binding site which consists of two histidine residues, a methionine residue, and a water molecule in a tetrahedral coordination sphere [Prigge et al. 1997]. This protein is found primarily in the pituitary gland, and its function is to C-terminally amidate bioactive peptides. There were no other structurally similarities between peptidylglycine monoxygenase and APP124-189.

While no examples of coordination spheres incorporating both methionine and tyrosine could be identified in the literature, there are several examples of copper coordination spheres which include the side- chains of tyrosine residues. An example is galactose oxidase (PDB accession number lgof) ; the copper coordination sphere of this protein includes two histidines and two tyrosine residues, and its function is the catalysis of the stereospecific oxidation of a broad range of primary alcohol substrates. The copper coordination site, which is the active site of this enzyme, has 5-coordinate square pyramidal coordination sphere. Acetate is the fifth ligand in the structure, and Tyr495 occupies the apex position of the pyramid (Ito et al. 1991). There no other structural similarities between APP124-189 and galactose oxidase.

The secondary shell about the metal binding site of APP124-189, defined as those residues within 3.5 A of a residue coordinating the metal (Karlin et al., 1997) is predominantly hydrophobic, with Alal54, Trop150, Leul65, Phel79, Vall82 and Phel84 all falling with this region.

Two hydrophilic residues, Lysl55 and Glu183, are also within 3.5 A of His151 and Tyrl68 and of His47 and Metl70, respectively.

The copper-binding site involving His137 and the N- terminus is considered to be an artefact of this particular construct, as the free amine of the N-terminus is a good metal ligand, as indicated by the binding of copper or nickel to albumin. The first two residues of the APP124-189 construct are Serl24 and Aspl25 ; these are exactly the same as the first two residues of thioredoxin.

The N-terminus of thioredoxin is a known copper-binding site, and its crystal structure (PDB accession code 2trx) has a copper which is bound to the N-terminus, a deprotonated backone amide (from D2) and the side-chain carboxyl of the Asp residue, while the fourth ligand is water (Holmgren et al. 1975). This metal-binding site

plays no known role in thioredoxin, and is thought to be opportunistic. In the structure of APP124-189 a better fourth ligand than water, His137, is available, as histidine has a high affinity for Cu2+. However, this second copper-binding site is an artefact of the construct which was used, since in the intact protein there is no free amino group at position 124.

The binding of Cu2+ to the tetrahedrally-arranged Hisl47, His151, Tyrl68 and Metl70 illustrated in Figure 4, may explain the redox chemistry associated with copper- binding to APP. In general Cu2+ favours a square planar coordination sphere about the metal, while Cu+ generally prefers a tetrahedral arrangement. The copper-binding site of APP is a rigid tetrahedral site, and Cu+ would be preferred. This site is also located on the surface of the molecule, which would leave the dangerous Cu'exposed, and may explain some of the toxic effects observed with this domain.

Example 3 : Mutagenesis data supporting the His-His-Tyr- Met binding site.

The NMR structure indicates that the copper-binding site is composed of His147, His151, Tyrl68, Metl70.

Mutagenesis experiments were performed to test this.

Hisl47 and His151 were mutated to Asn, Tyrl68 was mutated to Phe, and Metl70 was mutated to Leu. These mutations were incorporated into APP133-189. Recombinant protein was expressed in Pichia pastoris as described above, and purified by standard chromatography methods. The identities of the purified proteins were verified by mass spectrometry. The Cu-reducing activity of the CuBD was tested in a lipid peroxidation assay.

Two different assays of metal mediated lipid peroxidation were utilized. The first assay involved measuring the oxidative activity of metallated proteins.

This was determined by mixing dialyzed metallated or native protein at designated concentrations with 0.5mg/mL

low-density lipoprotein (LDL) for 24 hr (37°C). Lipid peroxidation was measured using a lipid peroxidation assay kit (LPO 486, Oxis International Inc. Portland, OR), as per kit instructions. The level of lipid peroxidation was determined by comparing absorbance (486 nm) with LDL alone (100% lipid peroxidation. The second assay was used to measure the lipid peroxidation activity of native proteins in the presence of free, non-protein-bound copper. This involved adding non-metallated peptides (140zM) to 0.5 mg/mL LDL together with 20pM Cu-glycine, and assaying for lipid peroxidation as for the metallated proteins.

The level of lipid peroxidation was determined by comparing the absorbance (486 nm) with LDL + Cu-gly (100% lipid peroxidation). As a negative control, LDL was also exposed to dialysed Cu-glycine solutions comparable to those used to Cu-metallate the proteins.

The results are summarized in Table 2. The control is LDL (0.5 mg/mL) in PBS buffer alone. The APP28-123 is a negative control, and represents background activity.

APP133-189 induced strong lipid peroxidation (3-fold above background). The Hisl47Asn mutation abolished this activity, indicating that this histidine residue is critical for activity. The Metl70Leu and Tyrl68Phe mutations also had a significant effect on the activity of the CuBD. The Hisl51Asn mutation also affected the activity, but to a lesser extent, indicating that His147 has a more important role than His151. Table 2 LDL oxidation activity of Cu-metallated APP proteins % of lipid peroxidation by control Control 100 APP28-123 130 APP133-189 312 Hisl47Asn 87 Hisl51Asn 196 Tyrl68Phe lll Metl70Leu 142 100 pM Cu 282

Example 4 : In silico docking The chemical structure databases, Maybridge and Aldrich, were obtained from Tripos (Tripos Associates, 1699 S. Hanley Road, St. Louis, MO 63144, USA) in Unity format. These were converted to mol2 format using dbtranslate. software (Tripos). The National Cancer Institute (NCI) database was downloaded from the World- Wide Web (http://dtp. nci. nih. gov/docs/3ddatabase/structuralinform ation/structural data. html) in MDL sd format. This was converted to mol2 format using the program babel (BABEL- 1.6. Walters, P. Stahl, M.

(babel@mercury. aichem. arizona. edu)).

All databases were corrected for atom and bond types using in-house software. Entries which included atoms which were not recognisable in the scoring routines were removed. Entries with single heavy atoms (including carbon, nitrogen, oxygen, sulphur, and phosphorus) were removed. Protonation state and atom charges were assigned using the sybdb DOCK ancillary software (Kuntz, 1992). A short minimization of each ligand was performed to ensure good geometry.

The databases contain the following numbers of entries: Aldrich (l) 58064 Aldrich (2) 106733 Maybridge 57114 National Cancer Institue (NCI) 115344 No attempt was made to ensure uniqueness between or within the databases. Some sites were docked to a reduced Aldrich database, in which the molecular weight was restricted to be less than 300 and the number of rotatable bonds to be less than 4 (Aldrich (l)).

Docking of entries from the databases to the protein sites was performed using the DOCK software suite. The energy grid used in DOCK was generated using the GRID software. A spacing of 0.25 Angstrom and an all-atom potential were used; apart from this, default parameters were used. Docking employed flexible ligands using the "torsion drive"option, with minimization. Potential sites for docking were initially identified by visual inspection using the InsightII software (Molecular Simulations Inc., San Diego, USA). Sites were further defined using ancillary DOCK software. All docking calculations were performed on a Beowulf cluster running the Linux operating system. Scheduling of tasks was performed using the Enfuzion software (TurboLinux Inc., 2000 Sierra Point Parkway, Suite 702, Brisbane, CA 94005, USA.). Scoring of individual DOCKed solutions was performed using in-house software. The scoring software included several scoring algorithms: Score (Wang et al, 1998), PMF (Muegge et al, 1999), ChemScore (Eldridge et al, 1997) and SmoG (DeWitte et al, 1996; 1997).

Alternatives which involve subtle differences in these measures were also calculated, using Dock-Score Quality Estimate (Tao and Lai, 2001), and ChemScore with rotatable bond correction (Stahl and Rarey, 2001); SMoG score per heavy atom in the ligand and ligand intramolecular energies were also estimated (Baxter et al, 1998). Scoring

was performed on the twenty-five solutions of lowest energy obtained from DOCK using a consensus measure (Wang and Wang, 2001).

From the four databases searched, 41 compounds showed a consensus score which was regarded as providing a potentially useful degree of fit. Representative structures thus identified are shown below.

1- {4- [4- (4-Acetyl-phenyl)-buta-1, 3-dienyl]-phenyl}-ethanone <BR> (9H-Carbazol-2-yl)- (3-phenyl-allylidene)-amine (7, 12-Dimethyl-benzo [a] anthracen-5-yl)-methanediol

(2,5-Dimethyl-phenyl)-carbamic acid naphthalen-2-yl ester

1-Naphthalen-1-yl-3-p-tolyl-propenone 9-Methyl-dibenzo [a, c] phenazine 5,2', 5"-Trimethyl- [1, 1' ; 3', 1"] terphenyl-2, 5', 2" -triol

Maybridge back 3- (4-lodo-phenyl)-1-phenyl-imidazo [1,5-a] pyridine (4-Chloro-phenyl)- (4, 5-dimethyl-2-phenyl-thieno [2, 3-d]pyrimidin-6-yl)- methanone NCIBack

2,6-Bis- (5-benzoyl-2, 4-dihydroxy-phenyl)-pyran-4-one

N- (9H-Fluoren-2-yl)-/V-phenyl-hydrazine Of these, compounds 28879,32499,35548,42623, 45007, and 48219 from the Aldrich database docked to the principal copper-binding site encompassing residues His 147, His 151, Tyrl68 and Met 170 (identified as (a) herein), while Maybridge compounds 21056 and 54249, NCI compounds 31526 and 37643, and Aldrich compounds 76137 and 81972 docked to the secondary binding sites encompassing Leul36, Glnl38, Glu139, Argl40, Metl41, Vall43, Glu145, His149, Trpl50, Vall53, Alal54, Thrl57, Argl80, Glyl81, Vall82 and Phel84 or His147, His151, Tyrl68, Metl70,

Alal54, Trpl50, Lysl55, Leul65, Phel79, Vall82, and Glu183, identified herein as (b) and (c) respectively.

Docking of (2,5-dimethyl-phenyl)-carbamic acid napthalen-2-yl ester (Compound 42613) to the principal copper-binding site of APP is illustrated in Figure 6, and docking of 3-(4-Iodo-phenyl)-l-phenyl-imidazo [1-5- a] pyridine (Compound 21056) to the secondary copper- binding site of APP which is located at the back of the copper-binding domain and encompasses the residues listed in (b) is shown in Figure 7.

Example 5: Cell based assay for Aß production.

Ap production is measured using either cell lines or primary cells. Cell lines can be either transfected with APP cDNA or untransfected. Cells are grown using suitable culture medium. The test compound is dissolved in an appropriate solvent, for example DMSO. The cells are treated with different concentrations of the test compound for different lengths of time. Ap levels are measured by either western blotting or ELISA. The western blot assay involves separating either culture supernatant or cell lysate on SDS-PAGE, followed by western blotting to a membrane. The Ap is detected using an antibody against Ap. The levels of Ap are quantitated by measuring the intensity of the Ap signal or signals with a suitable detector, such as a phosphorimager or a densitometer. The change in Ap level is determined by comparing to a non- drug treated control. An alternative method involves first immunoprecipitating the Ap with an anti-Ap antibody from either the culture supernatant or cell lysate prior to the SDS-PAGE step. The ELISA assay can be performed using a commercially-available ELISA kit (for example Human Amyloid AP (1-42) ELISA kit from IBL Hamburg, http://www. ibl-hamburg. com/prod/jp_17711_amyloid-b-1- 42. htm). The assay is performed in a ELISA plate which has been coated with an anti-Ap antibody. The cell supernatant or cell lysate is added to the plate and

incubated for a period of time. The plate is washed and then incubate with another anti-Ap antibody. After a period of time the plate is washed. The amount of bound antibody may be measured using a reporter molecule that is coupled to the second antibody (for example horse radish peroxidase). The change in Ap level is determined by comparing to a non-drug treated control.

Example 6 : Real Time Surface Plasmon Resonance Analysis Real time binding experiments are performed on a BIACORE system equipped with the Upgrade kit (BIACORE, Pharmacia). All experiments are performed at 37°C. To prepare a metal chelating sensor surface, a nitrilotriacetic acid immobilized sensor ship (Sensor chip NTA, BIACORE, Uppsala, Sweden) is exposed to copper solution (100LM CUC12 in Milli-Q water) for 4 min at a flow rate of 5p1/min. For control experiments the sensor surface is treated as above, but by injecting EDTA (1pM) for 4 min.

Surface Plasmon Resonance analysis (SPR) buffers and solutions are filtered and degassed: eluent buffer (PBS, 0.005% n-octylglycopyranoside, 1pM EDTA, pH7.4), dispenser buffer (PBS, 0.005% n-octylglycopyranoside, 3mM EDTA) and regeneration solutions I (50mM EDTA) and II (45 mM EDTA, 1 mM bathocuproine disulphonate (BC). After extensive washing to reset the surface with regeneration buffer I followed by eluent buffer, individual flow cells are loaded with copper solution to saturate the surface with Cu (II). The signal for binding of Cu (II) to NTA is normally about 40 RU. Peptide stock solutions are prepared in 1pM EDTA (1 mg/ml), diluted in PBS (30pg/ml) and injected on to the surface for 2 min (10go) by using the KINJECT command. The sensorgram is allowed to run for an additional 20 min after the end of injection to determine the dissociation kinetics. Subsequent treatment with regeneration solution II for 6 min results in return to the baseline signal, indicating that the surface has

completely been cleaned. Two observations are central to confirm the reliability of this approach. First, APP peptides do not show binding to the NTA surface when it has not previously been loaded with Cu (II). Second, the injection of 1mM BC for 2 min on to the Cu (II)-charged NTA surface does not affect surface bound RU, showing that peptide binding is specific and exclusively mediated by Cu (II) but not Cu (I).

Sensorgrams are analyzed using the BIAevaluation 3.0 program (BIACORE) and kinetic constants are obtained by fitting curves to a single-site binding model (A+B=AB).

Using this method we have been able to demonstrate that APP124-189 is able to reduce Cu (II) to Cu (I), despite the fact that this fragment has no free cysteine residues.

Rational drug design The process of rational drug design requires no explanation or teaching for the skilled person, but a brief description of computational design is given here for the lay reader. Various computational analyses are necessary to determine whether a molecule is sufficiently complementary to the target moiety or structure to be useful as a pharmaceutical agent. Some of these analyses are discussed above. Such analyses may be carried out in current software applications, such as the Molecular Similarity application of QUANTA (Molecular Simulations Inc., Waltham, Mass.) version 3.3, and as described in the accompanying User's Guide, Volume 3 pages 134-135.

The Molecular Similarity application permits comparisons between different structures, different conformations of the same structure, and different parts of the same structure. The procedure used in Molecular Similarity to compare structures is divided into four steps: 1) load the structures to be compared ; 2) define the atom equivalences in these structures;

3) perform a fitting operation; and 4) analyze the results.

Each structure is identified by a name. One structure is identified as the target (ie., the fixed structure); all remaining structures are working structures (ie., moving structures). When a rigid fitting method is used, the working structure is translated and rotated to obtain an optimum fit with the target structure. The fitting operation uses a least squares fitting algorithm which computes the optimum translation and rotation to be applied to the moving structure, such that the root mean square difference of the fit over the specified pairs of equivalent atom is an absolute minimum.

This number, given in angstroms, is reported by QUANTA.

One skilled in the art may use one of several methods to screen chemical entities or fragments for their ability to associate with a target site. Again, these methods require no elucidation for the skilled person, but are described here for the benefit of the unskilled reader. The screening process begins by visual inspection of the target site on the computer screen, generated from a machine-readable storage medium. Selected fragments or chemical entitles may then be positioned in a variety of orientations, or docked, within that binding pocket as defined above. Docking may be accomplished using software such as Quanta and Sybyl, followed by energy minimization and molecular dynamics with standard molecular mechanics force fields, such as CHARMM and AMBER.

Specialized computer programs may also assist in the process of selected fragments or chemical entities. These include: 1. GRID (Goodford, 1985). GRID is available from Oxford University, Oxford, UK.

2. MCSS (Miranker et al., 1991). MCSS is available from Molecular Simulations, Burlington, Mass.

3. AUTODOCK (Goodsell, 1990). AUTODOCK is available from Scripps Research Institute, La Jolla, Calif.

4. DOCK (Kuntz, 1982). DOCK is available from University of California, San Francisco, Calif.

Once suitable chemical entities or fragments have been selected, they can be assembled into a single compound or complex. Assembly may be preceded by visual inspection of the relationship of the fragments to each other on the three-dimensional image displayed on a computer screen in relation to the structure coordinates of the target compound or site. This would be followed by manual model building using software such as Quanta or Sybyl.

Useful programs to aid one of skill in the art in connecting the individual chemical entities or fragments include: 1. CAVEAT (Bartlett, 1989). CAVEAT is available from the University of California, Berkeley, Calif.

2.3D Database systems such as MACCS-3D (MDL Information Systems, San Leandro, Calif.). This area is reviewed by Martin (1992).

3. HOOK (available from Molecular Simulations Burlington, Mass.).

As the skilled reader will already know, instead of proceeding to build a ligand for the target in a step-wise fashion, one fragment or chemical entity at a time as described above, target-binding compounds may be designed as a whole or de novo. These methods include: 1. LUDI (Bohm, 1992). LUDI is available from the Biosym Technologies, San Diego, Calif.

2. LEGEND (Nishibata, 1991). LEGEND is available from Molecular Simulations, Burlington, Mass.

3. LeapFrog (available from Tripos Associates, St.

Louis. Mo.).

Other molecular modelling techniques may also be employed. See for example Cohen (1990). See also Navia (1992).

Once a compound has been designed or selected by such methods, the efficiency with which that compound can

bind to a target site may be tested and optimized by computational evaluation. For example, an effective ligand will preferably demonstrate a relatively small difference in energy between its bound and free states, ie. a small deformation energy of binding. Thus the most efficient ligand should preferably be designed with a deformation energy of binding of not greater than about 10kcal/mole, preferably, not greater than 7 kcal/mole.

Ligands may interact with the target in more than one conformation that is similar in overall binding energy.

In those cases, the deformation energy of binding is taken to be the difference between the energy of the free entity and the average energy of the conformations observed when the inhibitor binds to the protein.

An entity designed or selected as binding to a target may be further computionally optimized so that in its bound states it would preferably lack repulsive electrostatic interaction with the target enzyme. Such non-complementary (e. g., electrostatic) interactions include repulsive charge-charge, dipole-dipole and charge- dipole interactions. Specifically, the sum of all electrostatic interactions between the ligand and the target, when the ligand is bound to the target, preferably makes a neutral or favourable contribution to the enthalpy of binding.

Specific computer software is available in the art to evaluate compound deformation energy and electrostatic interaction. Examples of programs designed for such uses include: Gaussian 92, revision C [M. J. Frisch, Gaussian, Inc., Pittsburgh, Pa. COPYRGT. 1992] ; AMBER, version 4.0 [P. A. Kollman, University of California at San Francisco, COPYRGT. 1994]; QUANTA/CHARMM [Molecular Simulations, Inc., Burlington, Mass. COPYRGT. 1994]; and Insight II/Discover (Biosysm Technologies Inc., San Diego, Calif.

COPYRGT. 1994). These programs may be implemented, for instance, using a Silicon Graphics workstation, IRIS 4D/35 or IBM RISC/6000 workstation model 550. Other hardware

systems and software packages will be known to those skilled in the art.

Once the ligand has been optimally selected or designed, as described above, substitutions may then be made in some of its atoms or side groups in order to improve or modify its. binding properties. Generally initial substitutions are conservative, ie., the replacement group will have approximately the same size, shape, hydrophobicity and charge as the original group.

It should, of course, be understood that components known in the art to alter conformation should be avoided. Such substituted chemical compounds may then be analyzed for efficiency of fit to the desired target site by the same computer methods described in detail, above. Again, all these facts are familiar to the skilled person.

Another approach is the computational screening of small molecule data bases for chemical entities or compounds which can bind in whole, or in part, to a desired target. In this screening, the quality of fit of such entities to the binding site may be judged either by shape complementarity or by estimated interaction energy.

(Meng, 1992).

The computational analysis and design of molecules, as well as software and computer systems therefor, are described in U. S Patent No. 5,978,740 which is included herein by reference, including specifically but not by way of limitation the computer system diagram described with reference to and illustrated in Figure 3 thereof, as well as the data storage media diagram described with reference to and illustrated in Figure 4s and 5 thereof.

It will be appreciated by persons skilled in the art that numerous variations and/or modifications may be made to the invention as shown in the specific embodiments without departing from the spirit or scope of the invention as broadly described. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive.

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APPENDIX A COMPND and2 1 MODEL 1 ATOM 1 N SER 124 15.435 16.723-1.916 1.00 0.00 ATOM 2 CA SER 124 14.680 15.504-2.280 1.00 0.00 ATOM 3 HA SER 124 14.134 15.687-3.193 1.00 0.00 ATOM 4 CB SER 124 15.689 14.380-2.503 1.00 0.00 ATOM 5 1HB SER 124 15.468 13.876-3.433 1.00 0.00 ATOM 6 2HB SER 124 15.626 13.674-1.686 1.00 0.00 ATOM 7 QB SER 124 15.547 13.775-2.559 1.00 0.00 ATOM 8 OG SER 124 17.011 14.901-2.563 1.00 0.00 ATOM 9 HG SER 124 17.641 14.174-2.647 1.00 0.00 ATOM 10 C SER 124 13.705 15.135-1. 175 1.00 0.00 ATOM 11 O SER 124 13.844 15.596-0.042 1.00 0.00 ATOM 12 1HT SER 124 15.200 17.006-0.942 1.00 0.00 ATOM 13 2HT SER 124 15.196 17.500-2.562 1.00 0.00 ATOM 14 3HT SER 124 16.457 16.534-1.975 1.00 0.00 ATOM 15 N ASP 125 12.724 14.315-1.514 1.00 0.00 ATOM 16 H ASP 125 12.668 13.990-2.440 1.00 0.00 ATOM 17 CA ASP 125 11.715 13.878-0.562 1.00 0.00 ATOM 18 HA ASP 125 11.807 14.479 0.330 1.00 0.00 ATOM 19 CB ASP 125 10.320 14.070-1.163 1.00 0.00 ATOM 20 1HB ASP 125 10.153 15.120-1.350 1.00 0.00 ATOM 21 2HB ASP 125 9.579 13.710-0.465 1.00 0.00 ATOM 22 QB ASP 125 9.866 14.415-0.907 1.00 0.00 ATOM 23 CG ASP 125 10.156 13.317-2.467 1.00 0.00 ATOM 24 OD1 ASP 125 10.810 13.703-3.460 1.00 0.00 ATOM 25 OD2 ASP 125 9.394 12.330-2.489 1.00 0.00 ATOM 26 C ASP 125 11.926 12.410-0.205 1.00 0.00 ATOM 27 O ASP 125 13.050 11.907-0.258 1.00 0.00 ATOM 28 N ALA 126 10.836 11.731 0.137 1.00 0.00 ATOM 29 H ALA 126 9.972 12.196 0.138 1.00 0.00 ATOM 30 CA ALA 126 10.874 10.317 0.488 1.00 0.00 ATOM 31 HA ALA 126 11.561 9.823-0.184 1.00 0.00 ATOM 32 QB ALA 126 11.496 10.085 2.251 1.00 0.00 ATOM 33 CB ALA 126 11.377 10.130 1.914 1.00 0.00 ATOM 34 1HB ALA 126 10.638 9.589 2.486 1.00 0.00 ATOM 35 2HB ALA 126 11.547 11.096 2.366 1.00 0.00 ATOM 36 3HB ALA 126 12.302 9.572 1.899 1.00 0.00 ATOM 37 C ALA 126 9.489 9.698 0.331 1.00 0.00 ATOM 38 O ALA 126 8.915 9.184 1.292 1.00 0.00 ATOM 39 N LEU 127 8.947 9.774-0.878 1.00 0.00 ATOM 40 H LEU 127 9.443 10.217-1.599 1.00 0. 00 ATOM 41 CA LEU 127 7.616 9.244-1.152 1.00 0.00 ATOM 42 HA LEU 127 7.066 9.241-0.225 1.00 0.00 ATOM 43 CB LEU 127 6.897 10.157-2.157 1. 00 0.00 ATOM 44 1HB LEU 127 7.113 9.795-3.151 1.00 0.00 ATOM 45 2HB LEU 127 7.311 11.151-2.063 1.00 0.00 ATOM 46 QB LEU 127 7.212 10.473-2.607 1.00 0.00 ATOM 47 CG LEU 127 5.371 10. 261-2.010 1.00 0.00 ATOM 48 HG LEU 127 5.068 11.275-2.231 1.00 0.00 ATOM 49 QD1 LEU 127 4.502 9.128-3.231 1.00 0.00 ATOM 50 QD2 LEU 127 4. 832 9.868-0.251 1.00 0.00 ATOM 51 CD1 LEU 127 4.668 9.345-2.998 1.00 0.00 ATOM 52 1HD1 LEU 127 3.621 9.274-2.741 1.00 0.00 ATOM 53 2HD1 LEU 127 5.116 8.363-2.959 1.00 0.00 ATOM 54 3HD1 LEU 127 4.767 9.748-3.995 1.00 0.00 ATOM 55 CD2 LEU 127 4.935 9.943-0. 588 1.00 0.00 ATOM 56 1HD2 LEU 127 5. 199 8.923-0.350 1. 00 0. 00 ATOM 57 2HD2 LEU 127 3.865 10.067-0.504 1.00 0.00 ATOM 58 3HD2 LEU 127 5.430 10.614 0.099 1.00 0.00 ATOM 59 QQD LEU 127 4.667 9.498-1.741 1.00 0.00 ATOM 60 C LEU 127 7.686 7.814-1.690 1. 00 0. 00 ATOM 61 O LEU 127 6.661 7.159-1.878 1.00 0.00 ATOM 62 N LEU 128 8.892 7.323-1.936 1.00 0.00 ATOM 63 H LEU 128 9.681 7.874-1.768 1.00 0. 00 ATOM 64 CA LEU 128 9.053 5.973-2.448 1. 00 0. 00 ATOM 65 HA LEU 128 8.091 5.491-2.405 1.00 0.00 ATOM 66 CB LEU 128 9.523 6.016-3.907 1.00 0.00

ATOM 67 1HB LEU 128 10.603 5.980-3.915 1.00 0.00 ATOM 68 2HB LEU 128 9.208 6.957-4.336 1.00 0.00 ATOM 69 QB LEU 128 9.906 6.468-4.125 1.00 0.00 ATOM 70 CG LEU 128 8.998 4.880-4.792 1.00 0.00 ATOM 71 HG LEU 128 8.608 4.091-4.165 1.00 0.00 ATOM 72 QD1 LEU 128 7.593 5.498-5.876 1.00 0.00 ATOM 73 QD2 LEU 128 10.380 4.170-5.852 1.00 0.00 ATOM 74 CD1 LEU 128 7.862 5.379-5.669 1.00 0.00 ATOM 75 1HD1 LEU 128 7.381 6.220-5.191 1.00 0.00 ATOM 76 2HD1 LEU 128 7.142 4.587-5.812 1.00 0.00 ATOM 77 3HD1 LEU 128 8.255 5.687-6.627 1.00 0.00 ATOM 78 CD2 LEU 128 10.115 4.305-5.649 1.00 0.00 ATOM 79 1HD2 LEU 128 10.896 5.043-5.764 1.00 0.00 ATOM 80 2HD2 LEU 128 9.723 4.044-6.621 1.00 0.00 ATOM 81 3HD2 LEU 128 10.519 3.425-5.173 1.00 0.00 ATOM 82 QQD LEU 128 8. 986 4.834-5.864 1.00 0.00 ATOM 83 C LEU 128 10.028 5.187-1.575 1.00 0.00 ATOM 84 O LEU 128 10.111 5.426-0.373 1.00 0.00 ATOM 85 N VAL 129 10.740 4.245-2.190 1.00 0.00 ATOM 86 H VAL 129 10.603 4.113-3.148 1.00 0.00 ATOM 87 CA VAL 129 11.710 3.389-1.492 1.00 0.00 ATOM 88 HA VAL 129 11.159 2.691-0.882 1.00 0.00 ATOM 89 CB VAL 129 12.555 2.583-2.504 1.00 0.00 ATOM 90 HB VAL 129 13.162 3.279-3.066 1.00 0.00 ATOM 91 QG1 VAL 129 13.711 1.387-1.625 1.00 0.00 ATOM 92 QG2 VAL 129 11.449 1.662-3.712 1.00 0.00 ATOM 93 CG1 VAL 129 13.489 1.615-1.794 1.00 0.00 ATOM 94 1HG1 VAL 129 13.836 0.870-2.493 1.00 0.00 ATOM 95 2HG1 VAL 129 12.961 1.132-0.984 1.00 0.00 ATOM 96 3HG1 VAL 129 14.335 2.159-1.398 1.00 0.00 ATOM 97 CG2 VAL 129 11.659 1.838-3.481 1.00 0.00 ATOM 98 1HG2 VAL 129 11.961 2.071-4.492 1.00 0.00 ATOM 99 2HG2 VAL 129 10.634 2.140-3.331 1.00 0.00 ATOM 100 3HG2 VAL 129 11.752 0.775-3.314 1.00 0.00 ATOM 101 QQG VAL 129 12.580 1.524-2.668 1.00 0.00 ATOM 102 C VAL 129 12.655 4.191-0.590 1.00 0.00 ATOM 103 O VAL 129 13.469 4.975-1.075 1.00 0.00 ATOM 104 N PRO 130 12.544 4.001 0.740 1.00 0.00 ATOM 105 CD PRO 130 11.593 3.108 1.400 1.00 0.00 ATOM 106 CA PRO 130 13.374 4.691 1.721 1.00 0.00 ATOM 107 HA PRO 130 13.540 5.713 1.444 1.00 0.00 ATOM 108 CB PRO 130 12.533 4.641 3.011 1.00 0.00 ATOM 109 1HB PRO 130 12.265 5.646 3.301 1.00 0.00 ATOM 110 2HB PRO 130 13.114 4.183 3.798 1.00 0.00 ATOM 111 QB PRO 130 12.690 4.914 3.550 1.00 0.00 ATOM 112 CG PRO 130 11.313 3.826 2.691 1.00 0.00 ATOM 113 1HG PRO 130 10.459 4. 479 2.577 1.00 0.00 ATOM 114 2HG PRO 130 11.132 3.112 3.482 1.00 0.00 ATOM 115 QG PRO 130 10.796 3.795 3.030 1.00 0.00 ATOM 116 1HD PRO 130 10.690 3.009 0.817 1.00 0.00 ATOM 117 2HD PRO 130 12.035 2.140 1.587 1.00 0.00 ATOM 118 QD PRO 130 11.363 2.574 1.202 1.00 0.00 ATOM 119 C PRO 130 14.726 4. 012 1.931 1.00 0.00 ATOM 120 O PRO 130 15.700 4.315 1.247 1.00 0.00 ATOM 121 N ASP 131 14.768 3.105 2.895 1.00 0.00 ATOM 122 H ASP 131 13.955 2.931 3.400 1.00 0.00 ATOM 123 CA ASP 131 15.993 2.377 3.228 1.00 0.00 ATOM 124 HA ASP 131 16.826 3.043 3.057 1.00 0.00 ATOM 125 CB ASP 131 15.973 1.980 4.712 1.00 0.00 ATOM 126 1HB ASP 131 15.135 1.323 4.893 1.00 0.00 ATOM 127 2HB ASP 131 15.861 2.870 5.312 1.00 0.00 ATOM 128 QB ASP 131 15.498 2.096 5.103 1.00 0.00 ATOM 129 CG ASP 131 17.238 1.273 5.149 1.00 0.00 ATOM 130 OD1 ASP 131 18.339 1.766 4.838 1.00 0.00 ATOM 131 OD2 ASP 131 17.131 0.211 5.795 1.00 0.00 ATOM 132 C ASP 131 16.167 1.141 2.337 1.00 0.00 ATOM 133 O ASP 131 16.585 1.249 1.188 1.00 0.00 ATOM 134 N LYS+ 132 15.849-0.037 2.870 1.00 0.00 ATOM 135 H LYS+ 132 15.526-0.072 3.794 1.00 0.00 ATOM 136 CA LYS+ 132 15.984-1.277 2.107 1.00 0.00 ATOM 137 HA LYS+ 132 16.515-1.044 1.196 1.00 0.00 ATOM 138 CB LYS+ 132 16.784-2.314 2.897 1.00 0.00

ATOM 139 1HB LYS+ 132 16.929-3.186 2.276 1.00 0.00 ATOM 140 2HB LYS+ 132 16.220-2.597 3.773 1.00 0.00 ATOM 141 QB LYS+ 132 16.575-2.892 3.025 1.00 0.00 ATOM 142 CG LYS+ 132 18.148-1.816 3.345 1.00 0.00 ATOM 143 1HG LYS+ 132 18.077-0.761 3.573 1.00 0.00 ATOM 144 2HG LYS+ 132 18.857-1.965 2.543 1.00 0.00 ATOM 145 QG LYS+ 132 18.467-1.363 3.058 1.00 0.00 ATOM 146 CD LYS+ 132 18.635-2.557 4.578 1.00 0.00 ATOM 147 1HD LYS+ 132 18.837-3.586 4.314 1.00 0.00 ATOM 148 2HD LYS+ 132 17.863-2.523 5.335 1.00 0.00 ATOM 149 QD LYS+ 132 18.350-3.055 4.825 1.00 0.00 ATOM 150 CE LYS+ 132 19.903-1.930 5.135 1.00 0.00 ATOM 151 1HE LYS+ 132 20.672-1.977 4.377 1.00 0.00 ATOM 152 2HE LYS+ 132 20.217-2.492 6.002 1.00 0.00 ATOM 153 QE LYS+ 132 20.445-2.235 5.190 1.00 0.00 ATOM 154 NZ LYS+ 132 19.694-0. 509 5.527 1.00 0.00 ATOM 155 1HZ LYS+ 132 20.056 0.131 4.790 1.00 0.00 ATOM 156 2HZ LYS+ 132 20.179-0.300 6.418 1.00 0.00 ATOM 157 3HZ LYS+ 132 18.667-0.311 5.653 1.00 0.00 ATOM 158 QZ LYS+ 132 19.634-0.160 5.621 1.00 0.00 ATOM 159 C LYS+ 132 14.620-1.845 1.744 1.00 0.00 ATOM 160 O LYS+ 132 14.516-2.819 1.002 1.00 0.00 ATOM 161 N CYS 133 13.575-1.226 2.260 1.00 0.00 ATOM 162 H CYS 133 13.718-0.450 2.836 1.00 0.00 ATOM 163 CA CYS 133 12.218-1.663 1.975 1.00 0.00 ATOM 164 HA CYS 133 12.252-2.710 1.713 1.00 0.00 ATOM 165 CB CYS 133 11.314-1.473 3.195 1.00 0.00 ATOM 166 1HB CYS 133 10.315-1.246 2.853 1.00 0.00 ATOM 167 2HB CYS 133 11.680-0.641 3.771 1.00 0.00 ATOM 168 QB CYS 133 10.998-0.944 3.312 1.00 0.00 ATOM 169 SG CYS 133 11.199-2.907 4.317 1.00 0.00 ATOM 170 C CYS 133 11.670-0.872 0.799 1.00 0.00 ATOM 171 0 CYS 133 12.066 0.265 0.573 1.00 0.00 ATOM 172 N LYS+ 134 10.755-1.468 0.058 1.00 0.00 ATOM 173 H LYS+ 134 10.463-2.374 0.292 1.00 0.00 ATOM 174 CA LYS+ 134 10.161-0.807-1.090 1.00 0.00 ATOM 175 HA LYS+ 134 10.852-0.050-1.430 1.00 0.00 ATOM 176 CB LYS+ 134 9.913-1.809-2.225 1.00 0.00 ATOM 177 1HB LYS+ 134 9.432-2.684-1.813 1.00 0.00 ATOM 178 2HB LYS+ 134 10.864-2.098-2.648 1.00 0.00 ATOM 179 QB LYS+ 134 10.148-2.391-2.230 1.00 0.00 ATOM 180 CG LYS+ 134 9.036-1.267-3.345 1.00 0.00 ATOM 181 1HG LYS+ 134 8.691-0.281-3.071 1.00 0.00 ATOM 182 2HG LYS+ 134 8.187-1.924-3.470 1.00 0.00 ATOM 183 QG LYS+ 134 8.439-1.103-3.270 1.00 0.00 ATOM 184 CD LYS+ 134 9.788-1.180-4.665 1.00 0.00 ATOM 185 1HD LYS+ 134 9.827-2.165-5.109 1.00 0.00 ATOM 186 2HD LYS+ 134 10. 794-0.833-4.473 1. 00 0.00 ATOM 187 QD LYS+ 134 10.311-1.499-4.791 1.00 0.00 ATOM 188 CE LYS+ 134 9.114-0.223-5.643 1.00 0.00 ATOM 189 1HE LYS+ 134 8.872-0.767-6.546 1.00 0.00 ATOM 190 2HE LYS+ 134 9.806 0.572-5.882 1.00 0.00 ATOM 191 QE LYS+ 134 9.339-0.098-6.214 1.00 0.00 ATOM 192 NZ LYS+ 134 7.864 0.374-5.085 1.00 0.00 ATOM 193 1HZ LYS+ 134 8.095 1.110-4.385 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.292-0.362-4.621 1.00 0.00 ATOM 195 3HZ LYS+ 134 7.300 0.802-5.848 1.00 0.00 ATOM 196 QZ LYS+ 134 7.563 0.516-4.951 1.00 0.00 ATOM 197 C LYS+ 134 8.863-0.140-0.685 1.00 0.00 ATOM 198 O LYS+ 134 7.908-0.807-0.304 1.00 0.00 ATOM 199 N PHE 135 8.835 1.174-0.767 1.00 0.00 ATOM 200 H PHE 135 9.630 1.652-1.078 1.00 0.00 ATOM 201 CA PHE 135 7.651 1.926-0.402 1.00 0.00 ATOM 202 HA PHE 135 7.089 1.340 0.312 1.00 0.00 ATOM 203 CB PHE 135 8.054 3.253 0.242 1.00 0.00 ATOM 204 1HB PHE 135 8.427 3.914-0.528 1.00 0.00 ATOM 205 2HB PHE 135 8.841 3.071 0.957 1.00 0.00 ATOM 206 QB PHE 135 8.634 3.492 0.215 1.00 0.00 ATOM 207 QD PHE 135 6.827 4. 051 1.044 1.00 0.00 ATOM 208 QE PHE 135 5.039 5.242 2.238 1.00 0.00 ATOM 209 QR PHE 135 5.574 4.885 1.880 1.00 0. 00 ATOM 210 CG PHE 135 6. 948 3.970 0.962 1.00 0.00

ATOM 211 CD1 PHE 135 7.005 5.343 1.132 1.00 0.00 ATOM 212 1HD PHE 135 7.847 5.892 0.734 1.00 0.00 ATOM 213 CE1 PHE 135 6.003 6.015 1.802 1.00 0.00 ATOM 214 1HE PHE 135 6.061 7.086 1.928 1.00 0.00 ATOM 215 CZ PHE 135 4. 927 5.316 2.311 1.00 0.00 ATOM 216 HZ PHE 135 4.140 5.839 2.837 1.00 0.00 ATOM 217 CE2 PHE 135 4. 857 3.948 2.147 1.00 0.00 ATOM 218 2HE PHE 135 4.016 3.399 2.547 1.00 0.00 ATOM 219 CD2 PHE 135 5.863 3.281 1.477 1.00 0.00 ATOM 220 2HD PHE 135 5.806 2.210 1.353 1.00 0.00 ATOM 221 C PHE 135 6.789 2.171-1.629 1.00 0.00 ATOM 222 O PHE 135 7.260 2.691-2.646 1.00 0.00 ATOM 223 N LEU 136 5.533 1.780-1.530 1.00 0.00 ATOM 224 H LEU 136 5.229 1.361-0.692 1.00 0.00 ATOM 225 CA LEU 136 4. 584 1.944-2.611 1.00 0.00 ATOM 226 HA LEU 136 5.091 2.428-3.431 1.00 0.00 ATOM 227 CB LEU 136 4.039 0.593-3.079 1.00 0.00 ATOM 228 1HB LEU 136 3.224 0.777-3.764 1.00 0.00 ATOM 229 2HB LEU 136 3.648 0.069-2.217 1.00 0.00 ATOM 230 QB LEU 136 3.436 0.423-2.990 1.00 0.00 ATOM 231 CG LEU 136 5.053-0.313-3.774 1.00 0.00 ATOM 232 HG LEU 136 5.873 0.288-4.133 1.00 0.00 ATOM 233 QD1 LEU 136 5.736-1.578-2.565 1.00 0.00 ATOM 234 QD2 LEU 136 4.266-1.177-5.246 1.00 0.00 ATOM 235 CD1 LEU 136 5. 606-1. 335-2.798 1.00 0.00 ATOM 236 1HD1 LEU 136 4.797-1.744-2.210 1.00 0.00 ATOM 237 2HD1 LEU 136 6.320-0.859-2.142 1.00 0.00 ATOM 238 3HD1 LEU 136 6.090-2.131-3.344 1.00 0.00 ATOM 239 CD2 LEU 136 4.418-1.011-4.965 1.00 0.00 ATOM 240 1HD2 LEU 136 4. 565-0.417-5.854 1.00 0.00 ATOM 241 2HD2 LEU 136 3.359-1.133-4.786 1.00 0.00 ATOM 242 3HD2 LEU 136 4.873-1.981-5.098 1.00 0.00 ATOM 243 QQD LEU 136 5.001-1.378-3.905 1.00 0.00 ATOM 244 C LEU 136 3.444 2.828-2.144 1.00 0.00 ATOM 245 O LEU 136 2.363 2.347-1.815 1.00 0.00 ATOM 246 N HIS+ 137 3.706 4.118-2.111 1.00 0.00 ATOM 247 H HIS+ 137 4.593 4.430-2.381 1.00 0.00 ATOM 248 CA HIS+ 137 2.720 5.093-1.684 1.00 0.00 ATOM 249 HA HIS+ 137 2.017 4.605-1.015 1.00 0. 00 ATOM 250 CB HIS+ 137 3.431 6.238-0.955 1.00 0.00 ATOM 251 1HB HIS+ 137 3.996 6.807-1.677 1.00 0.00 ATOM 252 2HB HIS+ 137 4.113 5.820-0.230 1.00 0.00 ATOM 253 QB HIS+ 137 4.055 6.313-0.953 1.00 0.00 ATOM 254 CG HIS+ 137 2.528 7.187-0.229 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.564 7.953-0.849 1.00 0.00 ATOM 256 CD2 HIS+ 137 2.461 7.498 1.083 1.00 0.00 ATOM 257 1HD HIS+ 137 1.356 7.959-1.814 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.947 8.691 0.054 1.00 0.00 ATOM 259 NE2 HIS+ 137 1.470 8.432 1.241 1.00 0.00 ATOM 260 2HD HIS+ 137 3.072 7.079 1.871 1.00 0.00 ATOM 261 1HE HIS+ 137 0.142 9.386-0.144 1.00 0.00 ATOM 262 2HE HIS+ 137 1.023 8.621 2.095 1. 00 0.00 ATOM 263 C HIS+ 137 1.993 5.627-2.909 1.00 0.00 ATOM 264 O HIS+ 137 2.530 6.469-3.632 1.00 0.00 ATOM 265 N GLN 138 0.795 5.126-3.162 1.00 0.00 ATOM 266 H GLN 138 0.417 4.441-2.562 1.00 0.00 ATOM 267 CA GLN 138 0.034 5.561-4.324 1.00 0.00 ATOM 268 HA GLN 138 0.418 6.526-4.622 1.00 0.00 ATOM 269 CB GLN 138 0.223 4.576-5.482 1.00 0.00 ATOM 270 1HB GLN 138-0.621 4.660-6.151 1.00 0.00 ATOM 271 2HB GLN 138 0.255 3.574-5.083 1.00 0.00 ATOM 272 QB GLN 138-0.183 4.117-5.617 1.00 0.00 ATOM 273 CG GLN 138 1.496 4.813-6.285 1.00 0.00 ATOM 274 1HG GLN 138 1.897 5.780-6.020 1.00 0.00 ATOM 275 2HG GLN 138 1.249 4.802-7.337 1.00 0.00 ATOM 276 QG GLN 138 1.573 5.291-6.678 1.00 0.00 ATOM 277 CD GLN 138 2.560 3.760-6.030 1.00 0.00 ATOM 278 OE1 GLN 138 2.396 2.596-6.391 1.00 0.00 ATOM 279 NE2 GLN 138 3.661 4.159-5.405 1.00 0.00 ATOM 280 1HE2 GLN 138 3.732 5.103-5.143 1.00 0.00 ATOM 281 2HE2 GLN 138 4.357 3.496-5.231 1.00 0.00 ATOM 282 QE2 GLN 138 4.045 4.299-5.187 1.00 0.00

ATOM 283 C GLN 138-1.444 5.708-3.996 1.00 0.00 ATOM 284 O GLN 138-2. 029 4.875-3.297 1.00 0.00 ATOM 285 N GLU 139-2.038 6.776-4.503 1.00 0.00 ATOM 286 H GLU 139-1.512 7.399-5.044 1.00 0.00 ATOM 287 CA GLU 139-3.445 7.059-4.269 1.00 0.00 ATOM 288 HA GLU 139-3.747 6.517-3.387 1.00 0.00 ATOM 289 CB GLU 139-3.656 8.559-4.028 1.00 0.00 ATOM 290 1HB GLU 139-4.118 8.692-3.060 1.00 0.00 ATOM 291 2HB GLU 139-4.320 8.942-4.788 1.00 0.00 ATOM 292 QB GLU 139-4.219 8.817-3.924 1.00 0.00 ATOM 293 CG GLU 139-2.374 9.383-4.058 1.00 0.00 ATOM 294 1HG GLU 139-2.632 10.421-4.210 1.00 0.00 ATOM 295 2HG GLU 139-1.761 9.044-4.878 1.00 0.00 ATOM 296 QG GLU 139-2.196 9.732-4.544 1.00 0.00 ATOM 297 CD GLU 139-1.573 9.267-2.779 1.00 0.00 ATOM 298 OE1 GLU 139-2.147 9.503-1.696 1.00 0.00 ATOM 299 OE2 GLU 139-0.375 8.927-2.861 1.00 0.00 ATOM 300 C GLU 139-4.297 6.595-5.447 1.00 0.00 ATOM 301 O GLU 139-4.301 7.216-6.510 1.00 0.00 ATOM 302 N ARG+ 140-5.024 5.506-5.247 1.00 0.00 ATOM 303 H ARG+ 140-4.988 5.060-4.375 1.00 0.00 ATOM 304 CA ARG+ 140-5.891 4.962-6.282 1.00 0.00 ATOM 305 HA ARG+ 140-5.519 5.293-7.241 1.00 0.00 ATOM 306 CB ARG+ 140-5.876 3.428-6.231 1.00 0.00 ATOM 307 1HB ARG+ 140-6.443 3.106-5.367 1.00 0.00 ATOM 308 2HB ARG+ 140-4.855 3.093-6.124 1.00 0.00 ATOM 309 QB ARG+ 140-5.649 3.099-5.745 1.00 0.00 ATOM 310 CG ARG+ 140-6.470 2.760-7.461 1.00 0.00 ATOM 311 1HG ARG+ 140-7.385 3.273-7.728 1.00 0.00 ATOM 312 2HG ARG+ 140-6.688 1.729-7.228 1.00 0. 00 ATOM 313 QG ARG+ 140-7.036 2.501-7.478 1.00 0.00 ATOM 314 CD ARG+ 140-5.515 2.809-8.643 1.00 0. 00 ATOM 315 1HD ARG+ 140-4.505 2.900-8.270 1. 00 0.00 ATOM 316 2HD ARG+ 140-5.755 3.677-9.243 1.00 0.00 ATOM 317 QD ARG+ 140-5.130 3.288-8.756 1.00 0.00 ATOM 318 NE ARG+ 140-5.611 1.612-9.478 1.00 0.00 ATOM 319 HE ARG+ 140-5.185 0.793-9.143 1.00 0.00 ATOM 320 CZ ARG+ 140-6. 226 1.583-10.662 1.00 0.00 ATOM 321 NH1 ARG+ 140-6.854 2.663-11.110 1.00 0. 00 ATOM 322 1HH1 ARG+ 140-6.872 3.508-10. 554 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.319 2.650-11.995 1.00 0.00 ATOM 324 QH1 ARG+ 140-7.095 3.079-11.274 1.00 0.00 ATOM 325 NH2 ARG+ 140-6.235 0.466-11.383 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.780-0.357-11.040 1.00 0.00 ATOM 327 2HH2 ARG+ 140-6.697 0.444-12.271 1.00 0. 00 ATOM 328 QH2 ARG+ 140-6.238 0.043-11.655 1.00 0.00 ATOM 329 C ARG+ 140-7.313 5.481-6.093 1.00 0.00 ATOM 330 O ARG+ 140-8.150 4.809-5.494 1. 00 0.00 ATOM 331 N MET 141-7.579 6.683-6.602 1.00 0.00 ATOM 332 H MET 141-6.865 7.167-7.068 1.00 0.00 ATOM 333 CA MET 141-8.902 7.307-6.485 1.00 0.00 ATOM 334 HA MET 141-9.230 7.193-5.464 1.00 0.00 ATOM 335 CB MET 141-8.799 8.804-6.811 1.00 0.00 ATOM 336 1HB MET 141-8. 787 8.922-7.886 1.00 0.00 ATOM 337 2HB MET 141-7.874 9.185-6.407 1.00 0.00 ATOM 338 QB MET 141-8.330 9.053-7.146 1.00 0.00 ATOM 339 CG MET 141-9.941 9.641-6.255 1.00 0.00 ATOM 340 1HG MET 141-10.803 9.003-6.122 1.00 0.00 ATOM 341 2HG MET 141-10.178 10.417-6.967 1.00 0.00 ATOM 342 QG MET 141-10. 490 9.710-6.544 1.00 0.00 ATOM 343 SD MET 141-9.539 10.409-4.675 1.00 0.00 ATOM 344 QE MET 141-9.257 12.455-5.278 1.00 0.00 ATOM 345 CE MET 141-9.305 12.113-5.177 1.00 0.00 ATOM 346 1HE MET 141-9.408 12.759-4.317 1.00 0.00 ATOM 347 2HE MET 141-10.046 12.377-5.917 1.00 0. 00 ATOM 348 3HE MET 141-8.318 12.231-5.600 1.00 0.00 ATOM 349 C MET 141-9.929 6.639-7.409 1.00 0.00 ATOM 350 O MET 141-10.845 7.291-7.913 1.00 0.00 ATOM 351 N ASP 142-9.768 5.343-7.617 1.00 0.00 ATOM 352 H ASP 142-9.024 4.884-7.183 1.00 0.00 ATOM 353 CA ASP 142-10.657 4.579-8.466 1.00 0.00 ATOM 354 HA ASP 142-11.348 5.260-8. 938 1.00 0.00

ATOM 355 CB ASP 142-9.856 3.844-9.541 1.00 0.00 ATOM 356 1HB ASP 142-10.533 3.510-10.302 1.00 0.00 ATOM 357 2HB ASP 142-9.375 2.987-9. 096 1.00 0.00 ATOM 358 QB ASP 142-9.954 3.248-9.699 1.00 0.00 ATOM 359 CG ASP 142-8.791 4.701-10.190 1.00 0.00 ATOM 360 OD1 ASP 142-9.038 5.219-11.292 1.00 0.00 ATOM 361 OD2 ASP 142-7.688 4.817-9.614 1.00 0.00 ATOM 362 C ASP 142-11. 432 3.558-7.648 1.00 0.00 ATOM 363 O ASP 142-12.654 3.454-7.749 1.00 0.00 ATOM 364 N VAL 143-10.704 2.787-6.851 1.00 0.00 ATOM 365 H VAL 143-9.733 2.909-6.824 1.00 0.00 ATOM 366 CA VAL 143-11.314 1.751-6.032 1.00 0.00 ATOM 367 HA VAL 143-12.284 1.529-6.453 1.00 0.00 ATOM 368 CB VAL 143-10.470 0.457-6.048 1.00 0.00 ATOM 369 HB VAL 143-9.804 0.476-5.195 1.00 0.00 ATOM 370 QG1 VAL 143-11.570-1.059-5.896 1.00 0.00 ATOM 371 QG2 VAL 143-9.422 0.354-7.608 1.00 0.00 ATOM 372 CG1 VAL 143-11. 361-0.769-5.925 1.00 0.00 ATOM 373 lHGl VAL 143-12.207-0.666-6.587 1.00 0.00 ATOM 374 2HG1 VAL 143-11. 707-0.862-4.907 1.00 0.00 ATOM 375 3HG1 VAL 143-10.796-1.649-6.196 1.00 0.00 ATOM 376 CG2 VAL 143-9.622 0.374-7.310 1.00 0.00 ATOM 377 1HG2 VAL 143-9.956 1.119-8. 017 1.00 0.00 ATOM 378 2HG2 VAL 143-9.724-0.609-7.747 1.00 0.00 ATOM 379 3HG2 VAL 143-8.587 0.552-7.060 1.00 0.00 ATOM 380 QQG VAL 143-10.496-0.353-6.752 1.00 0.00 ATOM 381 C VAL 143-11.500 2.234-4. 594 1.00 0.00 ATOM 382 O VAL 143-10.721 3.042-4.095 1.00 0.00 ATOM 383 N CYS 144-12.543 1.742-3. 936 1.00 0.00 ATOM 384 H CYS 144-13. 135 1.105-4.386 1.00 0.00 ATOM 385 CA CYS 144-12.839 2.137-2.562 1.00 0.00 ATOM 386 HA CYS 144-11.958 2.609-2.143 1.00 0.00 ATOM 387 CB CYS 144-13.996 3.136-2.545 1.00 0.00 ATOM 388 1HB CYS 144-14.150 3.477-1.533 1.00 0.00 ATOM 389 2HB CYS 144-14.891 2.638-2. 889 1.00 0.00 ATOM 390 QB CYS 144-14.520 3.057-2.211 1.00 0.00 ATOM 391 SG CYS 144-13.744 4.604-3.597 1.00 0.00 ATOM 392 C CYS 144-13.206 0.937-1.707 1.00 0.00 ATOM 393 O CYS 144-14.357 0.508-1.703 1.00 0.00 ATOM 394 N GLU 145-12. 233 0.405-0.977 1.00 0.00 ATOM 395 H GLU 145-11.333 0.788-1. 014 1.00 0.00 ATOM 396 CA GLU 145-12.468-0.737-0.120 1.00 0.00 ATOM 397 HA GLU 145-13. 530-0.926-0.108 1.00 0.00 ATOM 398 CB GLU 145-11.768-1.957-0.678 1.00 0.00 ATOM 399 1HB GLU 145-11.478-2.601 0.137 1.00 0.00 ATOM 400 2HB GLU 145-10.881-1.638-1.204 1.00 0.00 ATOM 401 QB GLU 145-11.179-2.120-0. 533 1.00 0.00 ATOM 402 CG GLU 145-12.655-2.748-1.619 1.00 0.00 ATOM 403 1HG GLU 145-12.134-3.643-1.927 1.00 0.00 ATOM 404 2HG GLU 145-12.879-2.142-2.485 1.00 0.00 ATOM 405 QG GLU 145-12.506-2.893-2.206 1.00 0.00 ATOM 406 CD GLU 145-13.953-3.145-0.950 1.00 0.00 ATOM 407 OEl GLU 145-14. 971-2.458-1.167 1.00 0. 00 ATOM 408 OE2 GLU 145-13.945-4.119-0.175 1.00 0.00 ATOM 409 C GLU 145-12.003-0.471 1.296 1.00 0.00 ATOM 410 O GLU 145-11.414 0.572 1.587 1.00 0.00 ATOM 411 N THR 146-12.282-1.419 2.167 1.00 0.00 ATOM 412 H THR 146-12.756-2.219 1.858 1.00 0.00 ATOM 413 CA THR 146-11.918-1.310 3.568 1.00 0.00 ATOM 414 HA THR 146-12.138-0.301 3.885 1.00 0.00 ATOM 415 CB THR 146-12.768-2.282 4.390 1.00 0.00 ATOM 416 HB THR 146-12.308-3.260 4.365 1.00 0.00 ATOM 417 QG2 THR 146-12.971-1.781 6.186 1.00 0.00 ATOM 418 OG1 THR 146-14.068-2.384 3.830 1.00 0.00 ATOM 419 1HG THR 146-14.663-1.752 4.273 1.00 0.00 ATOM 420 CG2 THR 146-12.931-1.878 5.841 1.00 0.00 ATOM 421 1HG2 THR 146-13.799-2.370 6.256 1.00 0.00 ATOM 422 2HG2 THR 146-13.062-0.806 5.904 1.00 0.00 ATOM 423 3HG2 THR 146-12.053-2. 167 6.398 1.00 0.00 ATOM 424 C THR 146-10.424-1.569 3.769 1.00 0.00 ATOM 425 O THR 146-9. 734-2. 033 2.858 1.00 0.00 ATOM 426 N HIS+ 147-9.939-1.251 4.969 1.00 0. 00

ATOM 427 H HIS+ 147-10. 554-0.878 5.636 1.00 0.00 ATOM 428 CA HIS+ 147-8.530-1.422 5.333 1.00 0.00 ATOM 429 HA HIS+ 147-7.953-0.698 4.778 1.00 0.00 ATOM 430 CB HIS+ 147-8.349-1.155 6.831 1.00 0.00 ATOM 431 1HB HIS+ 147-8.226-2.100 7.342 1.00 0.00 ATOM 432 2HB HIS+ 147-9.231-0.661 7.210 1.00 0.00 ATOM 433 QB HIS+ 147-8.728-1.381 7.276 1.00 0.00 ATOM 434 CG HIS+ 147-7.167-0.298 7.160 1.00 0.00 ATOM 435 ND1 HIS+ 147-7.235 1.076 7.260 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.881-0.630 7.432 1.00 0.00 ATOM 437 1HD HIS+ 147-8.037 1.626 7.107 1.00 0.00 ATOM 438 CE1 HIS+ 147-6.045 1.552 7.580 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.204 0.539 7.691 1.00 0.00 ATOM 440 2HD HIS+ 147-5.461-1.628 7.425 1.00 0.00 ATOM 441 1HE HIS+ 147-5.800 2.595 7.727 1.00 0.00 ATOM 442 2HE HIS+ 147-4.228 0.625 7.754 1.00 0.00 ATOM 443 C HIS+ 147-8.013-2.822 5.005 1.00 0.00 ATOM 444 O HIS+ 147-6.854-2.989 4.635 1.00 0.00 ATOM 445 N LEU 148-8.875-3.820 5.159 1.00 0.00 ATOM 446 H LEU 148-9.781-3.624 5.467 1.00 0.00 ATOM 447 CA LEU 148-8.506-5.204 4.897 1.00 0.00 ATOM 448 HA LEU 148-7.612-5.417 5.463 1.00 0.00 ATOM 449 CB LEU 148-9.621-6.140 5.372 1.00 0.00 ATOM 450 1HB LEU 148-10.554-5.801 4.948 1.00 0.00 ATOM 451 2HB LEU 148-9.687-6.071 6.448 1.00 0.00 ATOM 452 QB LEU 148-10.120-5.936 5.698 1.00 0.00 ATOM 453 CG LEU 148-9.434-7.609 4.996 1.00 0.00 ATOM 454 HG LEU 148-9.043-7.666 3.992 1.00 0.00 ATOM 455 QD1 LEU 148-8.200-8.439 6.147 1.00 0.00 ATOM 456 QD2 LEU 148-11.079-8.516 5.034 1.00 0.00 ATOM 457 CD1 LEU 148-8.436-8.279 5.927 1.00 0.00 ATOM 458 lHD1 LEU 148-8.921-9.091 6.449 1.00 0.00 ATOM 459 2HD1 LEU 148-8.070-7.559 6.643 1.00 0.00 ATOM 460 3HD1 LEU 148-7.609-8.666 5.349 1.00 0.00 ATOM 461 CD2 LEU 148-10.765-8.341 5.027 1.00 0.00 ATOM 462 1HD2 LEU 148-11.058-8.512 6.052 1.00 0.00 ATOM 463 2HD2 LEU 148-10.665-9.289 4.519 1.00 0.00 ATOM 464 3HD2 LEU 148-11.516-7.745 4.531 1.00 0.00 ATOM 465 QQD LEU 148-9.639-8.477 5.591 1.00 0.00 ATOM 466 C LEU 148-8.212-5.447 3.418 1.00 0.00 ATOM 467 O LEU 148-7.228-6.105 3.084 1.00 0.00 ATOM 468 N HIS+ 149-9.064-4.933 2.532 1.00 0.00 ATOM 469 H HIS+ 149-9.839-4.422 2.844 1.00 0.00 ATOM 470 CA HIS+ 149-8.862-5.137 1.100 1.00 0.00 ATOM 471 HA HIS+ 149-8.819-6.205 0.938 1.00 0.00 ATOM 472 CB HIS+ 149-10.013-4.575 0.267 1.00 0.00 ATOM 473 1HB HIS+ 149-9.657-3.736-0.315 1.00 0.00 ATOM 474 2HB HIS+ 149-10.810-4.239 0.917 1.00 0.00 ATOM 475 QB HIS+ 149-10.233-3.988 0.301 1.00 0.00 ATOM 476 CG HIS+ 149-10.569-5.592-0.685 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.916-5.752-0.933 1.00 0.00 ATOM 478 CD2 HIS+ 149-9.938-6.519-1.449 1.00 0.00 ATOM 479 1HD HIS+ 149-12.649-5.208-0.538 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.090-6.731-1.804 1.00 0.00 ATOM 481 NE2 HIS+ 149-10.905-7.212-2.133 1.00 0.00 ATOM 482 2HD HIS+ 149-8.870-6.681-1.509 1.00 0.00 ATOM 483 1HE HIS+ 149-13.041-7.074-2.188 1.00 0.00 ATOM 484 2HE HIS+ 149-10.740-7.893-2.820 1.00 0.00 ATOM 485 C HIS+ 149-7.544-4.544 0.634 1.00 0.00 ATOM 486 O HIS+ 149-6.745-5.237 0.013 1.00 0.00 ATOM 487 N TRP 150-7. 314-3.272 0.934 1.00 0.00 ATOM 488 H TRP 150-7.992-2.765 1.432 1.00 0.00 ATOM 489 CA TRP 150-6. 070-2.612 0.534 1.00 0.00 ATOM 490 HA TRP 150-5.978-2.693-0.539 1.00 0.00 ATOM 491 CB TRP 150-6.076-1.139 0.935 1.00 0.00 ATOM 492 1HB TRP 150-5.102-0.718 0.726 1.00 0.00 ATOM 493 2HB TRP 150-6.268-1.065 1.995 1.00 0.00 ATOM 494 QB TRP 150-5.685-0.892 1.361 1.00 0.00 ATOM 495 CG TRP 150-7.099-0.306 0.227 1.00 0.00 ATOM 496 CD1 TRP 150-7. 538 0.928 0.606 1.00 0.00 ATOM 497 CD2 TRP 150-7.809-0.631-0.977 1.00 0.00 ATOM 498 CE3 TRP 150-7.812-1.729-1.843 1.00 0.00

ATOM 499 CE2 TRP 150-8.656 0.453-1.261 1.00 0.00 ATOM 500 NE1 TRP 150-8.475 1.388-0.281 1.00 0.00 ATOM 501 HD TRP 150-7.191 1.453 1.484 1.00 0.00 ATOM 502 3HE TRP 150-7.179-2.583-1.662 1.00 0.00 ATOM 503 CZ3 TRP 150-8. 644-1. 710-2. 939 1.00 0.00 ATOM 504 CZ2 TRP 150-9.491 0.471-2.369 1.00 0.00 ATOM 505 1HE TRP 150-8.940 2.248-0.223 1.00 0.00 ATOM 506 3HZ TRP 150-8.664-2.552-3.614 1.00 0.00 ATOM 507 CH2 TRP 150-9. 472-0. 617-3. 193 1.00 0.00 ATOM 508 2HZ TRP 150-10.138 1.309-2.585 1.00 0.00 ATOM 509 HH TRP 150-10.110-0.645-4.064 1.00 0.00 ATOM 510 C TRP 150-4. 874-3.298 1.154 1.00 0.00 ATOM 511 O TRP 150-3.816-3.358 0.545 1.00 0.00 ATOM 512 N HIS+ 151-5.050-3.831 2.353 1.00 0.00 ATOM 513 H HIS+ 151-5.928-3.763 2.786 1.00 0.00 ATOM 514 CA HIS+ 151-3.975-4. 537 3.025 1.00 0.00 ATOM 515 HA HIS+ 151-3.131-3.869 3.101 1.00 0.00 ATOM 516 CB HIS+ 151-4.418-4.970 4.431 1.00 0.00 ATOM 517 1HB HIS+ 151-5.275-5.624 4.339 1.00 0.00 ATOM 518 2HB HIS+ 151-4.706-4.094 4.992 1.00 0.00 ATOM 519 QB HIS+ 151-4.990-4.859 4.666 1.00 0.00 ATOM 520 CG HIS+ 151-3.369-5.696 5.223 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.977-5.310 6.485 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.644-6.802 4.930 1.00 0.00 ATOM 523 1HD HIS+ 151-3.320-4.535 6.982 1.00 0.00 ATOM 524 CE1 HIS+ 151-2.059-6.148 6.933 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.840-7.064 6.011 1.00 0.00 ATOM 526 2HD HIS+ 151-2. 681-7.362 4.002 1.00 0.00 ATOM 527 1HE HIS+ 151-1.558-6.084 7.889 1.00 0.00 ATOM 528 2HE HIS+ 151-1.341-7.894 6.156 1.00 0.00 ATOM 529 C HIS+ 151-3.581-5.749 2.192 1.00 0.00 ATOM 530 O HIS+ 151-2.399-6.004 1.966 1.00 0.00 ATOM 531 N THR 152-4.586-6.483 1.737 1.00 0.00 ATOM 532 H THR 152-5.505-6.221 1.951 1.00 0.00 ATOM 533 CA THR 152-4.359-7.664 0.926 1.00 0.00 ATOM 534 HA THR 152-3.605-8.260 1.420 1.00 0.00 ATOM 535 CB THR 152-5.644-8.487 0.807 1.00 0.00 ATOM 536 HB THR 152-6.249-8.082 0.009 1.00 0.00 ATOM 537 QG2 THR 152-5.336-10.297 0.431 1.00 0.00 ATOM 538 OG1 THR 152-6.389-8.430 2.014 1.00 0.00 ATOM 539 1HG THR 152-6.694-7.529 2.168 1.00 0.00 ATOM 540 CG2 THR 152-5.395-9.948 0.505 1.00 0.00 ATOM 541 1HG2 THR 152-5.217-10.072-0.556 1.00 0.00 ATOM 542 2HG2 THR 152-6.259-10.529 0.793 1.00 0.00 ATOM 543 3HG2 THR 152-4.532-10.289 1.056 1.00 0.00 ATOM 544 C THR 152-3. 830-7.284-0.449 1.00 0.00 ATOM 545 O THR 152-2.838-7.843-0.881 1.00 0.00 ATOM 546 N VAL 153-4.471-6.322-1.119 1.00 0.00 ATOM 547 H VAL 153-5.253-5.888-0.709 1.00 0.00 ATOM 548 CA VAL 153-4.016-5.888-2.442 1.00 0.00 ATOM 549 HA VAL 153-4.077-6.736-3.107 1.00 0.00 ATOM 550 CB VAL 153-4.896-4.749-3.009 1.00 0.00 ATOM 551 HB VAL 153-4.823-3.900-2.346 1.00 0.00 ATOM 552 QG1 VAL 153-4.299-4.222-4.713 1.00 0.00 ATOM 553 QG2 VAL 153-6.697-5.285-3.089 1.00 0.00 ATOM 554 CG1 VAL 153-4.413-4.322-4.387 1.00 0.00 ATOM 555 1HG1 VAL 153-3.384-4.624-4.517 1.00 0.00 ATOM 556 2HG1 VAL 153-4.489-3.249-4.479 1.00 0.00 ATOM 557 3HG1 VAL 153-5.024-4.793-5.143 1.00 0.00 ATOM 558 CG2 VAL 153-6.353-5.182-3.074 1.00 0.00 ATOM 559 1HG2 VAL 153-6.411-6.191-3.457 1.00 0.00 ATOM 560 2HG2 VAL 153-6.897-4.516-3.727 1.00 0.00 ATOM 561 3HG2 VAL 153-6.783-5.147-2.084 1.00 0.00 ATOM 562 QQG VAL 153-5.498-4.754-3.901 1.00 0.00 ATOM 563 C VAL 153-2.565-5.435-2.373 1.00 0.00 ATOM 564 O VAL 153-1.743-5.790-3.221 1.00 0.00 ATOM 565 N ALA 154-2.257-4.671-1.340 1.00 0.00 ATOM 566 H ALA 154-2.963-4.438-0.691 1.00 0.00 ATOM 567 CA ALA 154-0.906-4.187-1.123 1.00 0.00 ATOM 568 HA ALA 154-0.593-3. 635-1.998 1.00 0.00 ATOM 569 QB ALA 154-0.874-3.034 0.355 1.00 0.00 ATOM 570 CB ALA 154-0.880-3.255 0.072 1.00 0.00

ATOM 571 1HB ALA 154-0.488-3.780 0. 929 1.00 0.00 ATOM 572 2HB ALA 154-1.884-2.915 0.285 1.00 0.00 ATOM 573 3HB ALA 154-0. 250-2.405-0.149 1.00 0.00 ATOM 574 C ALA 154 0. 049-5.353-0.898 1.00 0.00 ATOM 575 O ALA 154 1.090-5.459-1.551 1.00 0.00 ATOM 576 N LYS+ 155-0.317-6.228 0.036 1.00 0.00 ATOM 577 H LYS+ 155-1.162-6.083 0.517 1.00 0.00 ATOM 578 CA LYS+ 155 0.493-7.396 0.363 1.00 0.00 ATOM 579 HA LYS+ 155 1.472-7.046 0.674 1.00 0.00 ATOM 580 CB LYS+ 155-0.149-8.190 1.508 1.00 0.00 ATOM 581 1HB LYS+ 155-1.179-8.395 1.248 1.00 0.00 ATOM 582 2HB LYS+ 155-0.131-7.588 2.404 1.00 0.00 ATOM 583 QB LYS+ 155-0.655-7.992 1.826 1.00 0. 00 ATOM 584 CG LYS+ 155 0.539-9.516 1.804 1.00 0.00 ATOM 585 1HG LYS+ 155 1.290-9.695 1.047 1.00 0. 00 ATOM 586 2HG LYS+ 155-0.199-10.304 1.773 1.00 0.00 ATOM 587 QG LYS+ 155 0.546-10.000 1.410 1.00 0.00 ATOM 588 CD LYS+ 155 1.204-9.517 3.174 1.00 0.00 ATOM 589 1HD LYS+ 155 0.437-9.483 3.935 1.00 0.00 ATOM 590 2HD LYS+ 155 1.832-8.642 3.258 1.00 0. 00 ATOM 591 QD LYS+ 155 1.135-9.063 3.597 1.00 0.00 ATOM 592 CE LYS+ 155 2.060-10.761 3.390 1.00 0.00 ATOM 593 1HE LYS+ 155 1.762-11.229 4.318 1.00 0.00 ATOM 594 2HE LYS+ 155 3.096-10.461 3.459 1.00 0.00 ATOM 595 QE LYS+ 155 2.429-10.845 3.889 1.00 0.00 ATOM 596 NZ LYS+ 155 1.917-11.748 2.279 1.00 0.00 ATOM 597 1HZ LYS+ 155 0.944-11.741 1.913 1.00 0.00 ATOM 598 2HZ LYS+ 155 2.140-12.706 2.618 1.00 0.00 ATOM 599 3HZ LYS+ 155 2.573-11.509 1.495 1.00 0.00 ATOM 600 QZ LYS+ 155 1.886-11.986 2.009 1.00 0.00 ATOM 601 C LYS+ 155 0.661-8.288-0.856 1.00 0.00 ATOM 602 O LYS+ 155 1.765-8.746-1.128 1.00 0.00 ATOM 603 N GLU 156-0.432-8.526-1.576 1.00 0.00 ATOM 604 H GLU 156-1.289-8.126-1.294 1.00 0.00 ATOM 605 CA GLU 156-0.405-9.360-2.773 1. 00 0.00 ATOM 606 HA GLU 156-0.130-10.361-2.477 1.00 0.00 ATOM 607 CB GLU 156-1.785-9.397-3.443 1.00 0.00 ATOM 608 1HB GLU 156-1.667-9.736-4.462 1.00 0.00 ATOM 609 2HB GLU 156-2.196-8.398-3.453 1.00 0.00 ATOM 610 QB GLU 156-1.931-9.067-3.957 1.00 0.00 ATOM 611 CG GLU 156-2.786-10.312-2.752 1.00 0.00 ATOM 612 1HG GLU 156-2.606-10.287-1.689 1.00 0.00 ATOM 613 2HG GLU 156-2.649-11.318-3.118 1.00 0.00 ATOM 614 QG GLU 156-2.627-10.803-2.403 1.00 0.00 ATOM 615 CD GLU 156-4.223-9.897-3.009 1.00 0.00 ATOM 616 OE1 GLU 156-5.135-10.677-2.670 1.00 0.00 ATOM 617 OE2 GLU 156-4.437-8.787-3.542 1.00 0.00 ATOM 618 C GLU 156 0.627-8.838-3.761 1. 00 0.00 ATOM 619 O GLU 156 1.513-9.571-4.174 1.00 0.00 ATOM 620 N THR 157 0.509-7.564-4.123 1.00 0.00 ATOM 621 H THR 157-0.227-7.031-3.747 1.00 0.00 ATOM 622 CA THR 157 1.437-6.934-5.064 1.00 0.00 ATOM 623 HA THR 157 1.281-7.395-6.028 1.00 0.00 ATOM 624 CB THR 157 1.128-5.436-5.179 1.00 0.00 ATOM 625 HB THR 157 1.404-4.950-4.254 1.00 0.00 ATOM 626 QG2 THR 157 2.051-4.588-6.572 1.00 0.00 ATOM 627 OG1 THR 157-0.256-5.222-5.401 1.00 0.00 ATOM 628 1HG THR 157-0.759-5.491-4.619 1.00 0.00 ATOM 629 CG2 THR 157 1.873-4.750-6.304 1.00 0.00 ATOM 630 1HG2 THR 157 2.469-5.477-6.838 1.00 0.00 ATOM 631 2HG2 THR 157 2.519-3.986-5.896 1.00 0.00 ATOM 632 3HG2 THR 157 1.164-4.299-6.982 1.00 0.00 ATOM 633 C THR 157 2.905-7.141-4.660 1.00 0.00 ATOM 634 O THR 157 3.759-7.412-5.505 1.00 0.00 ATOM 635 N CYS 158 3.201-7.001-3.374 1.00 0.00 ATOM 636 H CYS 158 2.487-6. 772-2.738 1.00 0.00 ATOM 637 CA CYS 158 4.570-7.166-2.889 1.00 0.00 ATOM 638 HA CYS 158 5.229-6.703-3.609 1.00 0.00 ATOM 639 CB CYS 158 4.735-6.452-1.550 1.00 0.00 ATOM 640 1HB CYS 158 5.607-6.830-1.050 1.00 0.00 ATOM 641 2HB CYS 158 3.869-6.654-0.942 1.00 0.00 ATOM 642 QB CYS 158 4.738-6.742-0.996 1.00 0.00

ATOM 643 SG CYS 158 4.903-4.638-1.699 1.00 0.00 ATOM 644 C CYS 158 4.959-8.642-2.767 1.00 0.00 ATOM 645 O CYS 158 6.052-9.033-3.180 1.00 0.00 ATOM 646 N SER 159 4.076-9.452-2.187 1.00 0.00 ATOM 647 H SER 159 3.230-9.080-1.861 1.00 0.00 ATOM 648 CA SER 159 4.337-10.879-2.000 1.00 0.00 ATOM 649 HA SER 159 5.315-10.968-1.552 1.00 0.00 ATOM 650 CB SER 159 3.311-11.489-1.047 1.00 0.00 ATOM 651 1HB SER 159 3.268-12.558-1.206 1.00 0.00 ATOM 652 2HB SER 159 2.340-11.056-1.242 1.00 0.00 ATOM 653 QB SER 159 2.804-11.807-1.224 1.00 0.00 ATOM 654 OG SER 159 3.670-11.236 0.306 1.00 0.00 ATOM 655 HG SER 159 4.634-11.188 0.370 1.00 0.00 ATOM 656 C SER 159 4.353-11.650-3.322 1.00 0.00 ATOM 657 O SER 159 5.014-12.680-3.416 1.00 0.00 ATOM 658 N GLU 160 3.647-11.148-4.340 1.00 0.00 ATOM 659 H GLU 160 3.141-10.315-4.215 1. 00 0.00 ATOM 660 CA GLU 160 3.629-11.803-5.650 1.00 0.00 ATOM 661 HA GLU 160 3.358-12.840-5.506 1.00 0.00 ATOM 662 CB GLU 160 2.614-11.134-6.586 1.00 0.00 ATOM 663 1HB GLU 160 3.049-10.228-6.981 1.00 0.00 ATOM 664 2HB GLU 160 1.730-10.881-6.018 1.00 0.00 ATOM 665 QB GLU 160 2.390-10.555-6.499 1.00 0.00 ATOM 666 CG GLU 160 2.189-12.008-7.755 1.00 0.00 ATOM 667 1HG GLU 160 2.769-12.919-7.737 1.00 0.00 ATOM 668 2HG GLU 160 2.384-11.478-8.675 1.00 0.00 ATOM 669 QG GLU 160 2.577-12.199-8.206 1.00 0.00 ATOM 670 CD GLU 160 0.720-12.369-7.713 1.00 0.00 ATOM 671 OE1 GLU 160 0.309-13.068-6.765 1.00 0.00 ATOM 672 OE2 GLU 160-0.018-11.954-8.630 1.00 0.00 ATOM 673 C GLU 160 5.029-11.733-6.246 1.00 0.00 ATOM 674 O GLU 160 5.445-12.581-7.037 1.00 0.00 ATOM 675 N LYS+ 161 5.761-10.720-5.808 1.00 0.00 ATOM 676 H LYS+ 161 5.370-10.109-5.153 1.00 0.00 ATOM 677 CA LYS+ 161 7.129-10.514-6.219 1.00 0.00 ATOM 678 HA LYS+ 161 7.276-11.001-7.172 1.00 0.00 ATOM 679 CB LYS+ 161 7.427-9.014-6.347 1.00 0.00 ATOM 680 1HB LYS+ 161 7.777-8.650-5.393 1.00 0.00 ATOM 681 2HB LYS+ 161 6.512-8.500-6.600 1.00 0.00 ATOM 682 QB LYS+ 161 7.145-8.575-5.996 1.00 0.00 ATOM 683 CG LYS+ 161 8.473-8.680-7.400 1.00 0.00 ATOM 684 1HG LYS+ 161 7.979-8.558-8.355 1.00 0.00 ATOM 685 2HG LYS+ 161 9.181-9.494-7.462 1.00 0.00 ATOM 686 QG LYS+ 161 8.580-9.026-7.908 1.00 0.00 ATOM 687 CD LYS+ 161 9.221-7.398-7.061 1.00 0.00 ATOM 688 1HD LYS+ 161 8.923-7.067-6.076 1.00 0.00 ATOM 689 2HD LYS+ 161 8.960-6.641-7.788 1.00 0.00 ATOM 690 QD LYS+ 161 8.942-6.854-6.932 1.00 0.00 ATOM 691 CE LYS+ 161 10.730-7.602-7.085 1.00 0.00 ATOM 692 1HE LYS+ 161 11.204-6.653-7.292 1.00 0.00 ATOM 693 2HE LYS+ 161 10.972-8.301-7.874 1.00 0.00 ATOM 694 QE LYS+ 161 11.088-7.477-7.583 1.00 0.00 ATOM 695 NZ LYS+ 161 11.247-8.133-5.792 1.00 0.00 ATOM 696 1HZ LYS+ 161 12.209-7.776-5.616 1.00 0.00 ATOM 697 2HZ LYS+ 161 11.283-9.183-5.819 1.00 0.00 ATOM 698 3HZ LYS+ 161 10.632-7.841-5.007 1.00 0.00 ATOM 699 QZ LYS+ 161 11.375-8.267-5.480 1.00 0.00 ATOM 700 C LYS+ 161 8.036-11.152-5.177 1.00 0.00 ATOM 701 O LYS+ 161 7.760-12.239-4.682 1.00 0.00 ATOM 702 N SER 162 9.105-10.470-4.829 1.00 0.00 ATOM 703 H SER 162 9.273-9.604-5.238 1.00 0.00 ATOM 704 CA SER 162 10. 019-10. 979-3.829 1.00 0.00 ATOM 705 HA SER 162 9.626-11.920-3.476 1.00 0.00 ATOM 706 CB SER 162 11.404-11.215-4.436 1.00 0.00 ATOM 707 1HB SER 162 11.641-12.269-4.380 1.00 0.00 ATOM 708 2HB SER 162 12.139-10.654-3.874 1.00 0.00 ATOM 709 QB SER 162 11.890-11.462-4.127 1.00 0.00 ATOM 710 OG SER 162 11.445-10.803-5.801 1. 00 0.00 ATOM 711 HG SER 162 11.572-11.581-6.361 1.00 0.00 ATOM 712 C SER 162 10.113-10.017-2.653 1.00 0.00 ATOM 713 O SER 162 11.206-9.618-2.266 1.00 0.00 ATOM 714 N THR 163 8.967-9.624-2.094 1.00 0.00

ATOM 715 H THR 163 8.110-9.956-2.450 1.00 0.00 ATOM 716 CA THR 163 8.959-8.710-0. 958 1.00 0.00 ATOM 717 HA THR 163 9.883-8.855-0.414 1.00 0.00 ATOM 718 CB THR 163 8.880-7.251-1.407 1.00 0.00 ATOM 719 HB THR 163 8.743-6.637-0.521 1.00 0. 00 ATOM 720 QG2 THR 163 10.406-6.628-2.297 1.00 0.00 ATOM 721 OG1 THR 163 7.779-7.052-2.273 1.00 0.00 ATOM 722 1HG THR 163 7.434-7.909-2.561 1.00 0.00 ATOM 723 CG2 THR 163 10.112-6.748-2.128 1.00 0.00 ATOM 724 1HG2 THR 163 10.636-6.044-1.496 1.00 0.00 ATOM 725 2HG2 THR 163 9.819-6.259-3.044 1.00 0.00 ATOM 726 3HG2 THR 163 10.763-7.581-2.353 1.00 0.00 ATOM 727 C THR 163 7.794-9.010-0.016 1.00 0.00 ATOM 728 O THR 163 6.820-9.664-0.389 1.00 0.00 ATOM 729 N ASN 164 7.898-8.512 1.204 1.00 0.00 ATOM 730 H ASN 164 8.703-7.996 1.437 1.00 0.00 ATOM 731 CA ASN 164 6.854-8.706 2.214 1.00 0.00 ATOM 732 HA ASN 164 6.005-9.173 1.726 1.00 0.00 ATOM 733 CB ASN 164 7.357-9.618 3.343 1.00 0.00 ATOM 734 1HB ASN 164 7.166-10.647 3.078 1.00 0.00 ATOM 735 2HB ASN 164 6.825-9.381 4.253 1.00 0.00 ATOM 736 QB ASN 164 6.996-10.014 3.666 1.00 0.00 ATOM 737 CG ASN 164 8.846-9.462 3.608 1.00 0.00 ATOM 738 OD1 ASN 164 9.533-10.429 3.907 1.00 0.00 ATOM 739 ND2 ASN 164 9.343-8.235 3.521 1.00 0.00 ATOM 740 1HD2 ASN 164 8.726-7.503 3.312 1.00 0.00 ATOM 741 2HD2 ASN 164 10.307-8.118 3.616 1.00 0.00 ATOM 742 QD2 ASN 164 9.517-7.811 3.464 1.00 0.00 ATOM 743 C ASN 164 6.417-7.369 2.807 1.00 0.00 ATOM 744 O ASN 164 7.255-6.543 3.164 1.00 0.00 ATOM 745 N LEU 165 5.109-7.159 2.910 1.00 0.00 ATOM 746 H LEU 165 4.492-7.853 2.610 1.00 0.00 ATOM 747 CA LEU 165 4.569-5.916 3.464 1.00 0.00 ATOM 748 HA LEU 165 5.036-5.084 2.956 1.00 0. 00 ATOM 749 CB LEU 165 3.057-5.840 3.261 1.00 0.00 ATOM 750 1HB LEU 165 2.587-5.734 4.227 1.00 0.00 ATOM 751 2HB LEU 165 2.722-6.764 2.814 1.00 0.00 ATOM 752 QB LEU 165 2.655-6.249 3.521 1.00 0.00 ATOM 753 CG LEU 165 2.586-4.691 2.395 1.00 0.00 ATOM 754 HG LEU 165 3.095-3.786 2.693 1.00 0.00 ATOM 755 QD1 LEU 165 3.000-5.028 0.602 1.00 0.00 ATOM 756 QD2 LEU 165 0.741-4.428 2.620 1.00 0.00 ATOM 757 CD1 LEU 165 2.921-4.963 0.948 1.00 0.00 ATOM 758 1HD1 LEU 165 3.749-4.339 0.645 1.00 0.00 ATOM 759 2HD1 LEU 165 2.060-4.742 0.331 1.00 0.00 ATOM 760 3HD1 LEU 165 3.190-6.001 0.829 1.00 0. 00 ATOM 761 CD2 LEU 165 1.095-4.479 2.577 1.00 0.00 ATOM 762 1HD2 LEU 165 0.555-5.286 2.104 1.00 0.00 ATOM 763 2HD2 LEU 165 0.807-3.541 2.124 1.00 0.00 ATOM 764 3HD2 LEU 165 0.860-4.457 3.631 1.00 0.00 ATOM 765 QQD LEU 165 1.871-4.728 1.611 1.00 0.00 ATOM 766 C LEU 165 4.865-5.802 4.946 1.00 0.00 ATOM 767 O LEU 165 4.483-6.666 5.732 1.00 0.00 ATOM 768 N HIS+ 166 5.531-4.724 5.313 1.00 0.00 ATOM 769 H HIS+ 166 5.798-4.069 4.632 1.00 0.00 ATOM 770 CA HIS+ 166 5.869-4.472 6.698 1.00 0.00 ATOM 771 HA HIS+ 166 5.559-5.328 7.279 1.00 0.00 ATOM 772 CB HIS+ 166 7.386-4.286 6.841 1.00 0.00 ATOM 773 1HB HIS+ 166 7.696-3.453 6.224 1.00 0.00 ATOM 774 2HB HIS+ 166 7.884-5.181 6.503 1.00 0.00 ATOM 775 QB HIS+ 166 7.790-4.317 6.364 1.00 0.00 ATOM 776 CG HIS+ 166 7.839-4.010 8.241 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.800-4.946 9.252 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.339-2.884 8.792 1.00 0.00 ATOM 779 1HD HIS+ 166 7.480-5.869 9.167 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.255-4.400 10.368 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.590-3.145 10. 114 1.00 0.00 ATOM 782 2HD HIS+ 166 8.494-1.937 8.283 1.00 0.00 ATOM 783 1HE HIS+ 166 8.339-4.895 11.325 1.00 0.00 ATOM 784 2HE HIS+ 166 8.747-2.459 10.796 1.00 0.00 ATOM 785 C HIS+ 166 5.121-3.236 7.198 1. 00 0. 00 ATOM 786 O HIS+ 166 4.460-3.279 8.235 1.00 0.00

ATOM 787 N ASP 167 5.224-2.142 6.446 1.00 0.00 ATOM 788 H ASP 167 5.762-2.175 5.625 1.00 0.00 ATOM 789 CA ASP 167 4.555-0.892 6.817 1.00 0.00 ATOM 790 HA ASP 167 4.060-1.057 7.763 1.00 0.00 ATOM 791 CB ASP 167 5.562 0.254 6. 981 1.00 0.00 ATOM 792 1HB ASP 167 5.170 0.965 7.694 1.00 0.00 ATOM 793 2HB ASP 167 5.689 0.747 6.029 1.00 0.00 ATOM 794 QB ASP 167 5.430 0.856 6.862 1.00 0.00 ATOM 795 CG ASP 167 6.924-0.200 7.462 1.00 0.00 ATOM 796 OD1 ASP 167 7.730-0.662 6.624 1.00 0.00 ATOM 797 OD2 ASP 167 7.192-0.087 8.676 1.00 0.00 ATOM 798 C ASP 167 3.509-0.493 5.779 1.00 0.00 ATOM 799 O ASP 167 3.802 0.234 4.833 1. 00 0.00 ATOM 800 N TYR 168 2.291-0.974 5.960 1.00 0.00 ATOM 801 H TYR 168 2.121-1.549 6.736 1.00 0.00 ATOM 802 CA TYR 168 1.186-0.669 5.050 1.00 0.00 ATOM 803 HA TYR 168 1.601-0.437 4.073 1.00 0.00 ATOM 804 CB TYR 168 0.260-1.882 4. 931 1.00 0. 00 ATOM 805 1HB TYR 168 0.622-2.529 4.147 1.00 0.00 ATOM 806 2HB TYR 168-0.735-1.544 4.684 1.00 0.00 ATOM 807 QB TYR 168-0.056-2.037 4.416 1.00 0.00 ATOM 808 QD TYR 168 0.167-2.785 6.356 1.00 0.00 ATOM 809 QE TYR 168 0. 041-4. 078 8.441 1.00 0. 00 ATOM 810 QR TYR 168 0.104-3.432 7.398 1.00 0.00 ATOM 811 CG TYR 168 0.174-2.693 6.207 1.00 0.00 ATOM 812 CD1 TYR 168 0.998-3.794 6.415 1.00 0.00 ATOM 813 1HD TYR 168 1.700-4.078 5.646 1.00 0.00 ATOM 814 CE1 TYR 168 0.930-4.523 7.586 1.00 0.00 ATOM 815 1HE TYR 168 1.579-5.374 7.730 1.00 0.00 ATOM 816 CZ TYR 168 0.032-4.156 8. 566 1.00 0.00 ATOM 817 CE2 TYR 168-0.795-3.069 8. 383 1.00 0.00 ATOM 818 2HE TYR 168-1.497-2.782 9. 151 1.00 0.00 ATOM 819 CD2 TYR 168-0.720-2.345 7.211 1.00 0.00 ATOM 820 2HD TYR 168-1.366-1.492 7.065 1.00 0.00 ATOM 821 OH TYR 168-0.041-4.880 9. 731 1.00 0.00 ATOM 822 HH TYR 168 0.683-4.627 10. 312 1.00 0.00 ATOM 823 C TYR 168 0.389 0.537 5.541 1.00 0.00 ATOM 824 0 TYR 168 0.257 0.758 6. 744 1.00 0.00 ATOM 825 N GLY 169-0.161 1.292 4.606 1.00 0.00 ATOM 826 H GLY 169-0.038 1.056 3.662 1.00 0.00 ATOM 827 CA GLY 169-0.957 2.450 4.948 1.00 0.00 ATOM 828 1HA GLY 169-0. 331 3.333 4.924 1.00 0.00 ATOM 829 2HA GLY 169-1.356 2.325 5.945 1.00 0.00 ATOM 830 QA GLY 169-0. 843 2.829 5.435 1.00 0.00 ATOM 831 C GLY 169-2.091 2.625 3.972 1.00 0.00 ATOM 832 O GLY 169-2. 056 2.056 2.880 1.00 0.00 ATOM 833 N MET 170-3.099 3.394 4.346 1.00 0.00 ATOM 834 H MET 170-3. 076 3.822 5.228 1.00 0.00 ATOM 835 CA MET 170-4.242 3.618 3.473 1.00 0.00 ATOM 836 HA MET 170-3.927 3.415 2.454 1.00 0.00 ATOM 837 CB MET 170-5.393 2.676 3.842 1.00 0.00 ATOM 838 1HB MET 170-6.311 3.073 3.432 1.00 0.00 ATOM 839 2HB MET 170-5.480 2.637 4.917 1.00 0.00 ATOM 840 QB MET 170-5.895 2.855 4.175 1.00 0.00 ATOM 841 CG MET 170-5.213 1.256 3.325 1.00 0.00 ATOM 842 1HG MET 170-4.563 1.283 2.463 1.00 0.00 ATOM 843 2HG MET 170-6.178 0.869 3.034 1.00 0.00 ATOM 844 QG MET 170-5.370 1.076 2.749 1.00 0.00 ATOM 845 SD MET 170-4.496 0.150 4.556 1.00 0.00 ATOM 846 QE MET 170-3.184-1.045 3.342 1.00 0.00 ATOM 847 CE MET 170-3.404-0.845 3.545 1.00 0.00 ATOM 848 1HE MET 170-3.129-0.290 2.659 1.00 0.00 ATOM 849 2HE MET 170-3.910-1.756 3.258 1.00 0.00 ATOM 850 3HE MET 170-2.515-1.089 4.107 1.00 0.00 ATOM 851 C MET 170-4.701 5.067 3.568 1.00 0.00 ATOM 852 O MET 170-5.086 5.535 4.639 1.00 0.00 ATOM 853 N LEU 171-4.652 5.774 2.448 1.00 0.00 ATOM 854 H LEU 171-4.334 5.345 1.625 1.00 0.00 ATOM 855 CA LEU 171-5.057 7.174 2.417 1.00 0.00 ATOM 856 HA LEU 171-5.308 7.464 3.427 1.00 0. oo ATOM 857 CB LEU 171-3. 919 8.066 1.918 1.00 0.00 ATOM 858 1HB LEU 171-3.930 8.978 2.493 1.00 0. 00

ATOM 859 2HB LEU 171-4.112 8.313 0.883 1.00 0.00 ATOM 860 QB LEU 171-4. 021 8.645 1.688 1.00 0.00 ATOM 861 CG LEU 171-2.521 7.468 2.008 1.00 0. 00 ATOM 862 HG LEU 171-2. 550 6.581 2.624 1.00 0.00 ATOM 863 QD1 LEU 171-1.906 6.976 0.300 1.00 0.00 ATOM 864 QD2 LEU 171-1.345 8.695 2.805 1.00 0.00 ATOM 865 CD1 LEU 171-2.025 7.070 0.627 1.00 0.00 ATOM 866 1HD1 LEU 171-2. 572 6.206 0.282 1.00 0.00 ATOM 867 2HD1 LEU 171-0. 972 6.832 0.678 1.00 0.00 ATOM 868 3HD1 LEU 171-2.174 7.891-0.062 1.00 0.00 ATOM 869 CD2 LEU 171-1.572 8.462 2.652 1.00 0.00 ATOM 870 1HD2 LEU 171-1.209 9.149 1.902 1.00 0.00 ATOM 871 2HD2 LEU 171-0.737 7.928 3.088 1.00 0.00 ATOM 872 3HD2 LEU 171-2. 091 9.009 3.424 1.00 0.00 ATOM 873 QQD LEU 171-1.625 7.836 1.552 1.00 0.00 ATOM 874 C LEU 171-6.272 7.388 1.531 1.00 0.00 ATOM 875 O LEU 171-6.982 6.439 1.192 1.00 0.00 ATOM 876 N LEU 172-6.480 8.657 1.162 1.00 0.00 ATOM 877 H LEU 172-5.852 9.339 1.478 1.00 0.00 ATOM 878 CA LEU 172-7.589 9.086 0.305 1.00 0.00 ATOM 879 HA LEU 172-7.733 10.143 0.471 1.00 0.00 ATOM 880 CB LEU 172-7.240 8.872-1.171 1.00 0.00 ATOM 881 1HB LEU 172-8.133 8.546-1.684 1.00 0.00 ATOM 882 2HB LEU 172-6.502 8.086-1.236 1.00 0.00 ATOM 883 QB LEU 172-7.317 8.316-1.460 1.00 0.00 ATOM 884 CG LEU 172-6.697 10.109-1.893 1.00 0.00 ATOM 885 HG LEU 172-6.594 9.886-2.945 1.00 0.00 ATOM 886 QDl LEU 172-7.882 11.558-1.720 1.00 0.00 ATOM 887 QD2 LEU 172-4. 999 10.574-1.230 1.00 0.00 ATOM 888 CD1 LEU 172-7.656 11.280-1.753 1.00 0.00 ATOM 889 1HD1 LEU 172-8.661 10.953-1.977 1.00 0.00 ATOM 890 2HD1 LEU 172-7.370 12.062-2.442 1.00 0.00 ATOM 891 3HD1 LEU 172-7.617 11.660-0.743 1.00 0.00 ATOM 892 CD2 LEU 172-5. 325 10.485-1.357 1.00 0.00 ATOM 893 1HD2 LEU 172-5. 310 11.536-1.112 1.00 0.00 ATOM 894 2HD2 LEU 172-4.575 10.281-2.108 1.00 0.00 ATOM 895 3HD2 LEU 172-5.112 9.905-0.472 1.00 0.00 ATOM 896 QQD LEU 172-6.440 11.066-1.475 1.00 0.00 ATOM 897 C LEU 172-8.892 8.369 0.645 1.00 0.00 ATOM 898 O LEU 172-9.390 7.570-0.148 1.00 0.00 ATOM 899 N PRO 173-9.468 8.647 1.830 1.00 0.00 ATOM 900 CD PRO 173-8.952 9.594 2.838 1.00 0.00 ATOM 901 CA PRO 173-10.720 8.019 2.259 1.00 0.00 ATOM 902 HA PRO 173-10.581 6.967 2.468 1.00 0.00 ATOM 903 CB PRO 173-11.075 8.760 3.550 1.00 0.00 ATOM 904 1HB PRO 173-11.524 8.072 4.252 1.00 0.00 ATOM 905 2HB PRO 173-11.767 9.560 3.329 1.00 0.00 ATOM 906 QB PRO 173-11.645 8.816 3.791 1.00 0.00 ATOM 907 CG PRO 173-9.776 9.285 4.057 1.00 0.00 ATOM 908 1HG PRO 173-9.287 8.536 4.661 1.00 0.00 ATOM 909 2HG PRO 173-9.944 10.183 4.634 1.00 0.00 ATOM 910 QG PRO 173-9.615 9.359 4.648 1. 00 0.00 ATOM 911 1HD PRO 173-7.905 9.415 3.034 1.00 0.00 ATOM 912 2HD PRO 173-9.110 10.615 2.524 1.00 0.00 ATOM 913 QD PRO 173-8.507 10.015 2.779 1.00 0.00 ATOM 914 C PRO 173-11.829 8.187 1.227 1.00 0.00 ATOM 915 O PRO 173-12.002 9.263 0.651 1.00 0.00 ATOM 916 N CYS 174-12.571 7.120 0.994 1.00 0.00 ATOM 917 H CYS 174-12.384 6.291 1.487 1.00 0.00 ATOM 918 CA CYS 174-13.663 7.145 0.035 1.00 0.00 ATOM 919 HA CYS 174-13.558 8.034-0.568 1.00 0.00 ATOM 920 CB CYS 174-13.613 5.915-0.867 1.00 0.00 ATOM 921 1HB CYS 174-14.087 5.089-0. 359 1.00 0.00 ATOM 922 2HB CYS 174-12.582 5.666-1.068 1.00 0. 00 ATOM 923 QB CYS 174-13.334 5.377-0.713 1.00 0.00 ATOM 924 SG CYS 174-14.451 6.135-2.470 1.00 0.00 ATOM 925 C CYS 174-14.993 7.200 0.764 1.00 0.00 ATOM 926 O CYS 174-15.901 7.928 0.373 1.00 0.00 ATOM 927 N GLY 175-15.088 6. 433 1.836 1.00 0.00 ATOM 928 H GLY 175-14.319 5.883 2.107 1.00 0.00 ATOM 929 CA GLY 175-16. 295 6.408 2.628 1.00 0.00 ATOM 930 1HA GLY 175-16.827 5.489 2.437 1.00 0.00

ATOM 931 2HA GLY 175-16.920 7.245 2.351 1.00 0.00 ATOM 932 QA GLY 175-16.873 6.367 2.394 1.00 0.00 ATOM 933 C GLY 175-15.979 6.497 4.098 1.00 0.00 ATOM 934 O GLY 175-14.950 7.051 4.479 1.00 0.00 ATOM 935 N ILE 176-16.848 5.943 4.923 1.00 0.00 ATOM 936 H ILE 176-17.645 5.506 4.559 1.00 0.00 ATOM 937 CA ILE 176-16.639 5.954 6.360 1.00 0.00 ATOM 938 HA ILE 176-16. 221 6.912 6.634 1.00 0.00 ATOM 939 CB ILE 176-17.970 5.760 7.118 1.00 0.00 ATOM 940 HB ILE 176-18.178 4.702 7.161 1.00 0.00 ATOM 941 QG2 ILE 176-17.836 6.403 8.880 1.00 0.00 ATOM 942 CG2 ILE 176-17.862 6.280 8.543 1.00 0.00 ATOM 943 1HG2 ILE 176-18.639 5.837 9.147 1.00 0.00 ATOM 944 2HG2 ILE 176-17.975 7.354 8.543 1.00 0.00 ATOM 945 3HG2 ILE 176-16. 895 6.019 8.949 1.00 0.00 ATOM 946 CG1 ILE 176-19. 116 6.464 6.390 1.00 0.00 ATOM 947 1HG1 ILE 176-18.917 6.463 5.329 1.00 0.00 ATOM 948 2HG1 ILE 176-19. 183 7.484 6.739 1.00 0.00 ATOM 949 QG1 ILE 176-19.050 6.973 6.034 1.00 0.00 ATOM 950 QD1 ILE 176-20.780 5.654 6.667 1.00 0.00 ATOM 951 CD1 ILE 176-20.461 5.810 6.613 1.00 0.00 ATOM 952 lHDl ILE 176-20.429 4.791 6.257 1.00 0.00 ATOM 953 2HD1 ILE 176-21.221 6.356 6.075 1.00 0.00 ATOM 954 3HD1 ILE 176-20.692 5.815 7.668 1.00 0.00 ATOM 955 C ILE 176-15.660 4.847 6.759 1.00 0.00 ATOM 956 O ILE 176-14.972 4.944 7.774 1.00 0.00 ATOM 957 N ASP 177-15.618 3.791 5.949 1.00 0.00 ATOM 958 H ASP 177-16.199 3.772 5.163 1.00 0.00 ATOM 959 CA ASP 177-14.742 2.651 6.207 1.00 0.00 ATOM 960 HA ASP 177-14.148 2.870 7.080 1.00 0.00 ATOM 961 CB ASP 177-15.590 1.399 6.477 1.00 0.00 ATOM 962 1HB ASP 177-16.443 1.671 7.081 1.00 0.00 ATOM 963 2HB ASP 177-14.992 0.675 7.011 1.00 0.00 ATOM 964 QB ASP 177-15.717 1.173 7.046 1.00 0.00 ATOM 965 CG ASP 177-16.093 0.753 5.194 1.00 0.00 ATOM 966 OD1 ASP 177-15.704-0.402 4.912 1.00 0.00 ATOM 967 OD2 ASP 177-16.863 1.409 4.459 1.00 0.00 ATOM 968 C ASP 177-13.817 2.362 5.026 1.00 0.00 ATOM 969 O ASP 177-12.833 1.629 5.157 1.00 0.00 ATOM 970 N LYS+ 178-14. 163 2.889 3.860 1.00 0.00 ATOM 971 H LYS+ 178-14.976 3.428 3.801 1.00 0.00 ATOM 972 CA LYS+ 178-13.386 2.626 2.658 1.00 0.00 ATOM 973 HA LYS+ 178-12.788 1.748 2.856 1.00 0.00 ATOM 974 CB LYS+ 178-14.329 2.304 1.502 1.00 0.00 ATOM 975 1HB LYS+ 178-13.762 2.264 0.586 1.00 0.00 ATOM 976 2HB LYS+ 178-15.072 3.082 1.427 1.00 0.00 ATOM 977 QB LYS+ 178-14.417 2.673 1.007 1.00 0.00 ATOM 978 CG LYS+ 178-15.034 0.966 1.695 1.00 0.00 ATOM 979 1HG LYS+ 178-15.362 0.894 2.725 1.00 0.00 ATOM 980 2HG LYS+ 178-14.333 0.173 1.488 1.00 0.00 ATOM 981 QG LYS+ 178-14.847 0.533 2.107 1.00 0.00 ATOM 982 CD LYS+ 178-16.238 0.798 0.785 1.00 0.00 ATOM 983 1HD LYS+ 178-15. 912 0.852-0.245 1.00 0.00 ATOM 984 2HD LYS+ 178-16.944 1.592 0.986 1.00 0.00 ATOM 985 QD LYS+ 178-16.428 1.222 0.371 1.00 0.00 ATOM 986 CE LYS+ 178-16.924-0.544 1.020 1.00 0.00 ATOM 987 1HE LYS+ 178-17.551-0.765 0.168 1.00 0.00 ATOM 988 2HE LYS+ 178-17.538-0.468 1.906 1.00 0.00 ATOM 989 QE LYS+ 178-17.544-0.617 1.037 1.00 0.00 ATOM 990 NZ LYS+ 178-15.946-1.656 1.205 1.00 0.00 ATOM 991 1HZ LYS+ 178-16.429-2.501 1.565 1.00 0.00 ATOM 992 2HZ LYS+ 178-15.209-1.383 1.885 1.00 0.00 ATOM 993 3HZ LYS+ 178-15.490-1.898 0.287 1.00 0.00 ATOM 994 QZ LYS+ 178-15.709-1.928 1.246 1.00 0.00 ATOM 995 C LYS+ 178-12.430 3.750 2.299 1.00 0.00 ATOM 996 O LYS+ 178-12.671 4.918 2.592 1.00 0.00 ATOM 997 N PHE 179-11.336 3.360 1.656 1.00 0.00 ATOM 998 H PHE 179-11.225 2.405 1.454 1.00 0.00 ATOM 999 CA PHE 179-10.293 4.283 1.237 1.00 0.00 ATOM 1000 HA PHE 179-10.618 5.290 1.448 1.00 0.00 ATOM 1001 CB PHE 179-8.991 4.001 1.991 1.00 0.00 ATOM 1002 1HB PHE 179-8.270 4.737 1.705 1.00 0. 00

ATOM 1003 2HB PHE 179-8.618 3.032 1.703 1.00 0.00 ATOM 1004 QB PHE 179-8.444 3.884 1.704 1.00 0.00 ATOM 1005 QD PHE 179-9.133 4.032 3.654 1.00 0.00 ATOM 1006 QE PHE 179-9.345 4.079 6.104 1.00 0.00 ATOM 1007 QR PHE 179-9.281 4.065 5.370 1.00 0.00 ATOM 1008 CG PHE 179-9.119 4.029 3.488 1.00 0.00 ATOM 1009 CD1 PHE 179-8.785 5.167 4.203 1.00 0.00 ATOM 1010 1HD PHE 179-8.429 6.040 3.675 1.00 0.00 ATOM 1011 CE1 PHE 179-8.902 5.196 5.580 1.00 0.00 ATOM 1012 1HE PHE 179-8. 638 6.089 6.126 1.00 0.00 ATOM 1013 CZ PHE 179-9.358 4.082 6.257 1.00 0.00 ATOM 1014 HZ PHE 179-9.451 4.103 7.333 1.00 0.00 ATOM 1015 CE2 PHE 179-9.694 2.941 5.556 1.00 0.00 ATOM 1016 2HE PHE 179-10.053 2.069 6.081 1.00 0.00 ATOM 1017 CD2 PHE 179-9.574 2.917 4.180 1.00 0.00 ATOM 1018 2HD PHE 179-9.838 2.024 3.633 1.00 0.00 ATOM 1019 C PHE 179-10. 025 4.139-0.245 1.00 0.00 ATOM 1020 O PHE 179-10.751 3.440-0.948 1.00 0.00 ATOM 1021 N ARG+ 180-8.961 4.783-0.703 1.00 0.00 ATOM 1022 H ARG+ 180-8.419 5.308-0.076 1.00 0.00 ATOM 1023 CA ARG+ 180-8.557 4.719-2.102 1.00 0.00 ATOM 1024 HA ARG+ 180-8.961 3.811-2.528 1.00 0.00 ATOM 1025 CB ARG+ 180-9.093 5.921-2.887 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.749 5.840-3.909 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.695 6.826-2.458 1.00 0.00 ATOM 1028 QB ARG+ 180-8.722 6.333-3.183 1.00 0.00 ATOM 1029 CG ARG+ 180-10.606 6.026-2.906 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.972 5.989-1.891 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.006 5.191-3.466 1.00 0.00 ATOM 1032 QG ARG+ 180-10.989 5.590-2.678 1.00 0.00 ATOM 1033 CD ARG+ 180-11.065 7.319-3.554 1.00 0.00 ATOM 1034 1HD ARG+ 180-11.897 7.101-4.208 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.249 7.725-4.136 1.00 0.00 ATOM 1036 QD ARG+ 180-11.073 7.413-4.172 1.00 0.00 ATOM 1037 NE ARG+ 180-11.483 8.312-2.565 1.00 0.00 ATOM 1038 HE ARG+ 180-11.035 8.294-1.688 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.428 9.225-2.790 1.00 0.00 ATOM 1040 NH1 ARG+ 180-13.033 9.276-3.973 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.777 8.629-4.694 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.744 9.957-4.147 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.260 9.293-4.420 1.00 0.00 ATOM 1044 NH2 ARG+ 180-12.768 10.081-1.833 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.313 10.040-0.934 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.476 10.768-1.998 1.00 0.00 ATOM 1047 QH2 ARG+ 180-12.894 10.404-1.466 1.00 0.00 ATOM 1048 C ARG+ 180-7.037 4.687-2.219 1.00 0.00 ATOM 1049 O ARG+ 180-6.495 4.294-3.243 1.00 0.00 ATOM 1050 N GLY 181-6.345 5.117-1.175 1.00 0.00 ATOM 1051 H GLY 181-6.817 5.427-0.370 1.00 0.00 ATOM 1052 CA GLY 181-4.896 5.140-1.224 1.00 0.00 ATOM 1053 1HA GLY 181-4.551 6.094-0.851 1.00 0.00 ATOM 1054 2HA GLY 181-4. 585 5.039-2.254 1.00 0.00 ATOM 1055 QA GLY 181-4.568 5.566-1.552 1.00 0.00 ATOM 1056 C GLY 181-4.252 4.039-0.417 1.00 0.00 ATOM 1057 O GLY 181-4.827 3.556 0.556 1.00 0.00 ATOM 1058 N VAL 182-3.048 3.650-0.823 1.00 0.00 ATOM 1059 H VAL 182-2.649 4.088-1.603 1.00 0.00 ATOM 1060 CA VAL 182-2.292 2.604-0.144 1.00 0.00 ATOM 1061 HA VAL 182-2.636 2.551 0.882 1.00 0.00 ATOM 1062 CB VAL 182-2.479 1.213-0.805 1.00 0.00 ATOM 1063 HB VAL 182-1.675 1.071-1.515 1.00 0.00 ATOM 1064 QG1 VAL 182-2.358-0.150 0.482 1.00 0.00 ATOM 1065 QG2 VAL 182-4.112 1.086-1.736 1.00 0.00 ATOM 1066 CG1 VAL 182-2.382 0.111 0.236 1.00 0.00 ATOM 1067 1HG1 VAL 182-2.324 0.551 1.221 1.00 0.00 ATOM 1068 2HG1 VAL 182-1.496-0.480 0.052 1.00 0.00 ATOM 1069 3HG1 VAL 182-3.255-0.520 0.173 1.00 0.00 ATOM 1070 CG2 VAL 182-3.800 1.111-1.558 1.00 0.00 ATOM 1071 1HG2 VAL 182-4.559 1.671-1.032 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.098 0.075-1.623 1.00 0. 00 ATOM 1073 3HG2 VAL 182-3.679 1.513-2.553 1.00 0.00 ATOM 1074 QQG VAL 182-3.235 0.468-0.627 1.00 0.00

ATOM 1075 C VAL 182-0.801 2.952-0.147 1.00 0.00 ATOM 1076 O VAL 182-0.237 3.275-1.191 1.00 0.00 ATOM 1077 N GLU 183-0.178 2.888 1.024 1.00 0.00 ATOM 1078 H GLU 183-0.692 2.628 1.819 1.00 0.00 ATOM 1079 CA GLU 183 1.245 3.195 1.179 1.00 0.00 ATOM 1080 HA GLU 183 1.684 3.296 0.196 1.00 0.00 ATOM 1081 CB GLU 183 1.421 4.505 1.954 1.00 0.00 ATOM 1082 1HB GLU 183 1.839 5.249 1.292 1.00 0.00 ATOM 1083 2HB GLU 183 2.111 4.335 2.768 1.00 0.00 ATOM 1084 QB GLU 183 1.975 4.792 2.030 1.00 0.00 ATOM 1085 CG GLU 183 0.132 5.059 2.540 1.00 0.00 ATOM 1086 1HG GLU 183-0.536 4.238 2.750 1.00 0.00 ATOM 1087 2HG GLU 183-0.325 5.717 1.815 1.00 0.00 ATOM 1088 QG GLU 183-0.430 4.977 2.283 1.00 0.00 ATOM 1089 CD GLU 183 0.358 5.838 3.818 1.00 0.00 ATOM 1090 OE1 GLU 183 1.034 6.886 3.763 1.00 0.00 ATOM 1091 OE2 GLU 183-0.150 5.404 4.870 1.00 0.00 ATOM 1092 C GLU 183 1.938 2.067 1.935 1.00 0.00 ATOM 1093 O GLU 183 1.972 2.065 3.158 1.00 0.00 ATOM 1094 N PHE 184 2.453 1.088 1.218 1.00 0.00 ATOM 1095 H PHE 184 2.377 1.117 0.245 1.00 0.00 ATOM 1096 CA PHE 184 3.090-0.058 1.859 1.00 0.00 ATOM 1097 HA PHE 184 2.968 0.068 2.922 1.00 0.00 ATOM 1098 CB PHE 184 2.389-1.359 1.444 1.00 0.00 ATOM 1099 1HB PHE 184 1.512-1.498 2.061 1.00 0.00 ATOM 1100 2HB PHE 184 3.063-2.189 1.611 1.00 0.00 ATOM 1101 QB PHE 184 2.288-1.844 1.836 1.00 0.00 ATOM 1102 QD PHE 184 1.900-1.413-0.169 1.00 0.00 ATOM 1103 QE PHE 184 1.168-1.540-2.510 1.00 0.00 ATOM 1104 QR PHE 184 1.386-1.504-1.808 1.00 0.00 ATOM 1105 CG PHE 184 1.951-1.408-0.004 1.00 0.00 ATOM 1106 CD1 PHE 184 0.917-0.607-0.470 1.00 0.00 ATOM 1107 1HD PHE 184 0.431 0.078 0.209 1.00 0.00 ATOM 1108 CE1 PHE 184 0.503-0.677-1.786 1.00 0.00 ATOM 1109 1HE PHE 184-0.303-0.048-2.133 1.00 0.00 ATOM 1110 CZ PHE 184 1.121-1.549-2.656 1.00 0.00 ATOM 1111 HZ PHE 184 0.795-1.610-3.683 1.00 0.00 ATOM 1112 CE2 PHE 184 2.152-2.348-2.209 1.00 0.00 ATOM 1113 2HE PHE 184 2.639-3.032-2.888 1.00 0.00 ATOM 1114 CD2 PHE 184 2.560-2.277-0.891 1.00 0.00 ATOM 1115 2HD PHE 184 3.368-2.904-0.547 1.00 0.00 ATOM 1116 C PHE 184 4.577-0.166 1.561 1.00 0.00 ATOM 1117 O PHE 184 5.018 0.031 0.433 1.00 0.00 ATOM 1118 N VAL 185 5.341-0.509 2.589 1.00 0.00 ATOM 1119 H VAL 185 4.919-0.664 3.462 1.00 0.00 ATOM 1120 CA VAL 185 6.778-0.680 2.466 1.00 0.00 ATOM 1121 HA VAL 185 7.079-0.354 1.478 1.00 0.00 ATOM 1122 CB VAL 185 7.544 0.153 3.523 1.00 0.00 ATOM 1123 HB VAL 185 7.734-0.480 4.383 1.00 0.00 ATOM 1124 QG1 VAL 185 9.193 0.736 2.849 1.00 0.00 ATOM 1125 QG2 VAL 185 6.528 1.625 4.101 1.00 0.00 ATOM 1126 CG1 VAL 185 8.878 0.624 2.977 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.648 0.442 3.711 1.00 0.00 ATOM 1128 2HG1 VAL 185 8.824 1.682 2.766 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.107 0.086 2.070 1.00 0.00 ATOM 1130 CG2 VAL 185 6.723 1.344 3.988 1.00 0.00 ATOM 1131 1HG2 VAL 185 6.932 2.196 3.360 1.00 0.00 ATOM 1132 2HG2 VAL 185 6.980 1.579 5.012 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.671 1.102 3.931 1.00 0.00 ATOM 1134 QQG VAL 185 7.861 1.181 3.475 1.00 0.00 ATOM 1135 C VAL 185 7.120-2.161 2.623 1.00 0.00 ATOM 1136 O VAL 185 7.040-2.717 3.717 1.00 0.00 ATOM 1137 N CYS 186 7.472-2.808 1.521 1.00 0.00 ATOM 1138 H CYS 186 7.499-2.321 0.666 1.00 0.00 ATOM 1139 CA CYS 186 7.799-4.227 1.546 1.00 0.00 ATOM 1140 HA CYS 186 7.574-4.598 2.538 1.00 0.00 ATOM 1141 CB CYS 186 6.940-4.992 0.532 1.00 0.00 ATOM 1142 1HB CYS 186 5.941-5.095 0.929 1.00 0.00 ATOM 1143 2HB CYS 186 7.362-5.973 0.387 1.00 0.00 ATOM 1144 QB CYS 186 6.652-5.534 0.658 1.00 0.00 ATOM 1145 SG CYS 186 6.804-4.215-1.108 1.00 0.00 ATOM 1146 C CYS 186 9.282-4.449 1.266 1.00 0.00

ATOM 1147 0 CYS 186 9.819-3.922 0.301 1.00 0.00 ATOM 1148 N CYS 187 9.946-5.229 2.109 1.00 0.00 ATOM 1149 H CYS 187 9.473-5.632 2.869 1.00 0.00 ATOM 1150 CA CYS 187 11.375-5.492 1.924 1.00 0.00 ATOM 1151 HA CYS 187 11.788-4.660 1.376 1.00 0.00 ATOM 1152 CB CYS 187 12.101-5.604 3.268 1.00 0.00 ATOM 1153 1HB CYS 187 12.906-6.319 3.173 1.00 0. 00 ATOM 1154 2HB CYS 187 11.406-5.952 4.018 1.00 0.00 ATOM 1155 QB CYS 187 12.156-6.136 3.596 1.00 0.00 ATOM 1156 SG CYS 187 12.816-4.038 3.862 1.00 0.00 ATOM 1157 C CYS 187 11.609-6.757 1.122 1.00 0.00 ATOM 1158 O CYS 187 10.811-7.688 1.180 1.00 0.00 ATOM 1159 N PRO 188 12.711-6.790 0.350 1.00 0.00 ATOM 1160 CD PRO 188 13.691-5.694 0.223 1.00 0.00 ATOM 1161 CA PRO 188 13.066-7.942-0.484 1.00 0.00 ATOM 1162 HA PRO 188 12.318-8.128-1.241 1.00 0.00 ATOM 1163 CB PRO 188 14.383-7.527-1.152 1.00 0.00 ATOM 1164 1HB PRO 188 14.376-7.837-2.186 1.00 0.00 ATOM 1165 2HB PRO 188 15.208-8.000-0.638 1.00 0.00 ATOM 1166 QB PRO 188 14.792-7.919-1.412 1.00 0.00 ATOM 1167 CG PRO 188 14.444-6.042-1.028 1.00 0.00 ATOM 1168 1HG PRO 188 13.979-5.581-1.886 1.00 0.00 ATOM 1169 2HG PRO 188 15.474-5.724-0.943 1.00 0.00 ATOM 1170 QG PRO 188 14.727-5.653-1.414 1.00 0.00 ATOM 1171 1HD PRO 188 13.193-4.743 0.109 1.00 0.00 ATOM 1172 2HD PRO 188 14.359-5.670 1.073 1.00 0.00 ATOM 1173 QD PRO 188 13.776-5.207 0.591 1.00 0.00 ATOM 1174 C PRO 188 13.279-9.214 0.333 1.00 0.00 ATOM 1175 O PRO 188 14.102-9.242 1.250 1.00 0.00 ATOM 1176 N LEU 189 12.540-10.254-0.023 1.00 0.00 ATOM 1177 H LEU 189 11.913-10.157-0.771 1.00 0.00 ATOM 1178 CA LEU 189 12.636-11.542 0.640 1.00 0.00 ATOM 1179 HA LEU 189 13.534-11.545 1.240 1.00 0.00 ATOM 1180 CB LEU 189 11.423-11.780 1.542 1.00 0.00 ATOM 1181 1HB LEU 189 10.562-11.942 0.912 1.00 0.00 ATOM 1182 2HB LEU 189 11.257-10.890 2.131 1.00 0.00 ATOM 1183 QB LEU 189 10.910-11.416 1.522 1.00 0.00 ATOM 1184 CG LEU 189 11.550-12.972 2.492 1.00 0.00 ATOM 1185 HG LEU 189 12.174-13.725 2.029 1.00 0.00 ATOM 1186 QD1 LEU 189 12.365-12.451 4.102 1.00 0.00 ATOM 1187 QD2 LEU 189 9.864-13.734 2.822 1.00 0.00 ATOM 1188 CD1 LEU 189 12.209-12.551 3.795 1.00 0.00 ATOM 1189 1HD1 LEU 189 13.189-12.149 3.587 1.00 0.00 ATOM 1190 2HD1 LEU 189 12.300-13.408 4.444 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.604-11.796 4.275 1.00 0.00 ATOM 1192 CD2 LEU 189 10.186-13.588 2.759 1.00 0.00 ATOM 1193 1HD2 LEU 189 10.308-14.497 3.328 1.00 0.00 ATOM 1194 2HD2 LEU 189 9.704-13.814 1.819 1.00 0.00 ATOM 1195 3HD2 LEU 189 9.580-12.890 3.317 1.00 0.00 ATOM 1196 QQD LEU 189 11. 115-13. 093 3.462 1.00 0.00 ATOM 1197 C LEU 189 12.729-12.650-0.404 1.00 0.00 ATOM 1198 OT1 LEU 189 13.312-13.709-0.098 1.00 0.00 ATOM 1199 OT2 LEU 189 12.217-12.442-1.527 1.00 0.00 TER ENDMDL MODEL 2 ATOM 1 N SER 124 13.731 15.795 4.516 1.00 0.00 ATOM 2 CA SER 124 14.326 14.574 3.916 1.00 0.00 ATOM 3 HA SER 124 14.676 14.808 2.922 1.00 0.00 ATOM 4 CB SER 124 15.507 14.153 4.787 1.00 0.00 ATOM 5 1HB SER 124 16.360 13.941 4.158 1.00 0.00 ATOM 6 2HB SER 124 15.241 13.266 5.345 1.00 0.00 ATOM 7 QB SER 124 15.800 13.603 4.751 1.00 0.00 ATOM 8 OG SER 124 15.852 15.188 5.699 1.00 0.00 ATOM 9 HG SER 124 16.557 14.882 6.283 1.00 0.00 ATOM 10 C SER 124 13.296 13.460 3.838 1.00 0.00 ATOM 11 O SER 124 13.622 12.279 3.950 1.00 0.00 ATOM 12 1HT SER 124 14.302 16.099 5.332 1.00 0.00 ATOM 13 2HT SER 124 12.758 15.600 4.839 1.00 0.00 ATOM 14 3HT SER 124 13.704 16.562 3.818 1.00 0.00 ATOM 15 N ASP 125 12.052 13.862 3.655 1.00 0.00 ATOM 16 H ASP 125 11.867 14.823 3.582 1.00 0.00

ATOM 17 CA ASP 125 10.936 12.945 3.566 1.00 0.00 ATOM 18 HA ASP 125 11.098 12.144 4.272 1.00 0.00 ATOM 19 CB ASP 125 9.648 13.688 3.931 1.00 0.00 ATOM 20 1HB ASP 125 8.967 13.005 4.415 1.00 0.00 ATOM 21 2HB ASP 125 9.191 14.069 3.030 1.00 0.00 ATOM 22 QB ASP 125 9.079 13.537 3.722 1.00 0.00 ATOM 23 CG ASP 125 9.911 14.855 4.870 1.00 0.00 ATOM 24 OD1 ASP 125 9.513 14.768 6.045 1.00 0.00 ATOM 25 OD2 ASP 125 10.546 15.847 4.434 1.00 0.00 ATOM 26 C ASP 125 10.848 12.369 2.163 1.00 0.00 ATOM 27 O ASP 125 11. 161 13.051 1.186 1.00 0.00 ATOM 28 N ALA 126 10.436 11.116 2.061 1.00 0.00 ATOM 29 H ALA 126 10.205 10.616 2.872 1.00 0.00 ATOM 30 CA ALA 126 10.326 10.465 0.766 1.00 0.00 ATOM 31 HA ALA 126 10.381 11.230 0.006 1.00 0.00 ATOM 32 QB ALA 126 11. 761 9.273 0.502 1.00 0.00 ATOM 33 CB ALA 126 11.487 9.502 0. 553 1.00 0.00 ATOM 34 1HB ALA 126 11.141 8.487 0.688 1.00 0.00 ATOM 35 2HB ALA 126 12.268 9.714 1.268 1.00 0.00 ATOM 36 3HB ALA 126 11.874 9.619-0.449 1.00 0.00 ATOM 37 C ALA 126 9. 004 9.728 0.634 1.00 0.00 ATOM 38 O ALA 126 8.586 9.009 1.539 1.00 0.00 ATOM 39 N LEU 127 8.360 9.905-0.509 1.00 0.00 ATOM 40 H LEU 127 8.754 10.483-1. 190 1.00 0.00 ATOM 41 CA LEU 127 7.089 9.254-0.788 1.00 0.00 ATOM 42 HA LEU 127 6.644 8.967 0.151 1.00 0.00 ATOM 43 CB LEU 127 6.160 10.228-1.518 1.00 0.00 ATOM 44 1HB LEU 127 6. 341 10.133-2.578 1.00 0.00 ATOM 45 2HB LEU 127 6.418 11.232-1.215 1.00 0.00 ATOM 46 QB LEU 127 6.379 10.682-1.897 1.00 0.00 ATOM 47 CG LEU 127 4.666 10.022-1.271 1.00 0.00 ATOM 48 HG LEU 127 4.492 8.996-0.978 1.00 0.00 ATOM 49 QD1 LEU 127 4.061 11.133 0. 119 1.00 0.00 ATOM 50 QD2 LEU 127 3.693 10.351-2.844 1.00 0.00 ATOM 51 CD1 LEU 127 4.178 10.921-0.147 1.00 0.00 ATOM 52 1HD1 LEU 127 3.927 11.892-0.546 1.00 0.00 ATOM 53 2HD1 LEU 127 4.955 11.025 0.596 1.00 0.00 ATOM 54 3HD1 LEU 127 3.302 10.482 0.308 1.00 0.00 ATOM 55 CD2 LEU 127 3.880 10.289-2.543 1.00 0.00 ATOM 56 1HD2 LEU 127 4.362 9.795-3.373 1.00 0.00 ATOM 57 2HD2 LEU 127 3.843 11.352-2.727 1.00 0.00 ATOM 58 3HD2 LEU 127 2.876 9.907-2.430 1.00 0.00 ATOM 59 QQD LEU 127 3.877 10.742-1.362 1.00 0.00 ATOM 60 C LEU 127 7.316 8.010-1.640 1.00 0.00 ATOM 61 O LEU 127 6.376 7.428-2.180 1.00 0.00 ATOM 62 N LEU 128 8.575 7.615-1.763 1.00 0.00 ATOM 63 H LEU 128 9.279 8.120-1.313 1.00 0.00 ATOM 64 CA LEU 128 8.935 6. 452-2.553 1.00 0.00 ATOM 65 HA LEU 128 8.029 5.915-2.783 1.00 0.00 ATOM 66 CB LEU 128 9.605 6.908-3.862 1.00 0.00 ATOM 67 1HB LEU 128 10.672 6.939-3.696 1.00 0.00 ATOM 68 2HB LEU 128 9.267 7.911-4.077 1.00 0.00 ATOM 69 QB LEU 128 9.969 7.425-3.887 1.00 0.00 ATOM 70 CG LEU 128 9.342 6.043-5.110 1.00 0.00 ATOM 71 HG LEU 128 8.941 6.675-5.891 1.00 0.00 ATOM 72 QD1 LEU 128 10.940 5.290-5.752 1.00 0.00 ATOM 73 QD2 LEU 128 8.072 4.697-4.767 1.00 0.00 ATOM 74 CD1 LEU 128 10.634 5.435-5.628 1.00 0.00 ATOM 75 1HD1 LEU 128 11.448 5.701-4.970 1.00 0.00 ATOM 76 2HD1 LEU 128 10.835 5. 811-6. 620 1.00 0.00 ATOM 77 3HD1 LEU 128 10.537 4.360-5.665 1.00 0.00 ATOM 78 CD2 LEU 128 8.316 4.955-4.832 1.00 0.00 ATOM 79 1HD2 LEU 128 8.634 4.365-3.985 1.00 0.00 ATOM 80 2HD2 LEU 128 8.222 4.319-5.699 1.00 0.00 ATOM 81 3HD2 LEU 128 7.360 5.409-4.615 1.00 0.00 ATOM 82 QQD LEU 128 9.506 4.994-5.259 1.00 0.00 ATOM 83 C LEU 128 9.862 5.547-1.739 1.00 0. 00 ATOM 84 O LEU 128 9.906 5.651-0.514 1.00 0.00 ATOM 85 N VAL 129 10.583 4.662-2.424 1.00 0.00 ATOM 86 H VAL 129 10.487 4.636-3.398 1.00 0.00 ATOM 87 CA VAL 129 11.503 3.717-1.785 1.00 0.00 ATOM 88 HA VAL 129 10.913 2.995-1.243 1.00 0.00

ATOM 89 CB VAL 129 12.325 2.962-2.856 1.00 0.00 ATOM 90 HB VAL 129 12.887 3.690-3.423 1.00 0.00 ATOM 91 QG1 VAL 129 13.549 1.767-2.072 1.00 0.00 ATOM 92 QG2 VAL 129 11.185 2.050-4.043 1.00 0.00 ATOM 93 CG1 VAL 129 13.314 1.996-2.222 1.00 0.00 ATOM 94 1HG1 VAL 129 13.748 1.370-2.988 1.00 0.00 ATOM 95 2HG1 VAL 129 12.804 1.378-1.498 1.00 0.00 ATOM 96 3HG1 VAL 129 14.097 2.555-1.729 1.00 0.00 ATOM 97 CG2 VAL 129 11.403 2.225-3.815 1.00 0.00 ATOM 98 1HG2 VAL 129 11.539 1.160-3.697 1.00 0.00 ATOM 99 2HG2 VAL 129 11.641 2.507-4.830 1.00 0.00 ATOM 100 3HG2 VAL 129 10.377 2.484-3.601 1.00 0.00 ATOM 101 QQG VAL 129 12.367 1.909-3.057 1.00 0.00 ATOM 102 C VAL 129 12.461 4.404-0.804 1.00 0.00 ATOM 103 O VAL 129 13.248 5.266-1.192 1.00 0.00 ATOM 104 N PRO 130 12.393 4.021 0. 489 1. 00 0.00 ATOM 105 CD PRO 130 11.466 3.011 1.025 1.00 0.00 ATOM 106 CA PRO 130 13.245 4.584 1.533 1.00 0.00 ATOM 107 HA PRO 130 13.381 5.641 1.400 1.00 0.00 ATOM 108 CB PRO 130 12.438 4.332 2.809 1.00 0.00 ATOM 109 1HB PRO 130 11.819 5.193 3.018 1.00 0.00 ATOM 110 2HB PRO 130 13.115 4.164 3.634 1.00 0.00 ATOM 111 QB PRO 130 12.467 4.678 3.326 1.00 0.00 ATOM 112 CG PRO 130 11.608 3.121 2.526 1.00 0.00 ATOM 113 1HG PRO 130 10.635 3.233 2.983 1.00 0.00 ATOM 114 2HG PRO 130 12.101 2.243 2.916 1.00 0.00 ATOM 115 QG PRO 130 11.368 2.738 2.949 1.00 0.00 ATOM 116 1HD PRO 130 10.450 3.229 0.729 1.00 0.00 ATOM 117 2HD PRO 130 11.749 2.022 0.693 1.00 0.00 ATOM 118 QD PRO 130 11.099 2.625 0.711 1.00 0.00 ATOM 119 C PRO 130 14.622 3.915 1.601 1.00 0.00 ATOM 120 O PRO 130 15.505 4.212 0.801 1.00 0.00 ATOM 121 N ASP 131 14.795 3.027 2.574 1.00 0.00 ATOM 122 H ASP 131 14. 055 2.853 3.182 1.00 0.00 ATOM 123 CA ASP 131 16.065 2.324 2.770 1.00 0.00 ATOM 124 HA ASP 131 16.862 3.000 2.497 1.00 0.00 ATOM 125 CB ASP 131 16.219 1.948 4.250 1.00 0.00 ATOM 126 1HB ASP 131 15.449 1.241 4.519 1.00 0.00 ATOM 127 2HB ASP 131 16.111 2.837 4.852 1.00 0.00 ATOM 128 QB ASP 131 15.780 2.039 4.685 1.00 0.00 ATOM 129 CG ASP 131 17.565 1.329 4.564 1.00 0.00 ATOM 130 OD1 ASP 131 17.597 0.122 4.879 1.00 0.00 ATOM 131 OD2 ASP 131 18.580 2.048 4.494 1.00 0.00 ATOM 132 C ASP 131 16.163 1.070 1.885 1.00 0.00 ATOM 133 O ASP 131 16.424 1.163 0.687 1.00 0.00 ATOM 134 N LYS+ 132 15.955-0.104 2.480 1.00 0.00 ATOM 135 H LYS+ 132 15.762-0.122 3.441 1.00 0.00 ATOM 136 CA LYS+ 132 16.034-1.363 1.741 1.00 0.00 ATOM 137 HA LYS+ 132 16.588-1.175 0.833 1.00 0.00 ATOM 138 CB LYS+ 132 16.774-2.426 2.567 1.00 0.00 ATOM 139 1HB LYS+ 132 16.078-2.871 3.262 1.00 0.00 ATOM 140 2HB LYS+ 132 17.563-1.941 3.126 1.00 0.00 ATOM 141 QB LYS+ 132 16.820-2.406 3.194 1.00 0.00 ATOM 142 CG LYS+ 132 17. 398-3.540 1.730 1.00 0.00 ATOM 143 1HG LYS+ 132 18.470-3.520 1.868 1.00 0.00 ATOM 144 2HG LYS+ 132 17.165-3.367 0.690 1.00 0.00 ATOM 145 QG LYS+ 132 17.817-3.444 1.279 1.00 0.00 ATOM 146 CD LYS+ 132 16.870-4.914 2.133 1.00 0.00 ATOM 147 1HD LYS+ 132 15.862-4.802 2.509 1.00 0.00 ATOM 148 2HD LYS+ 132 17.503-5.315 2.910 1.00 0.00 ATOM 149 QD LYS+ 132 16.682-5.059 2.709 1.00 0.00 ATOM 150 CE LYS+ 132 16.857-5.881 0.952 1.00 0.00 ATOM 151 1HE LYS+ 132 17.784-5.773 0.407 1.00 0.00 ATOM 152 2HE LYS+ 132 16.031-5.625 0.304 1.00 0.00 ATOM 153 QE LYS+ 132 16.907-5.699 0.355 1.00 0.00 ATOM 154 NZ LYS+ 132 16.710-7.304 1.384 1.00 0.00 ATOM 155 1HZ LYS+ 132 17.555-7.850 1. 119 1.00 0.00 ATOM 156 2HZ LYS+ 132 15.875-7.743 0.922 1.00 0.00 ATOM 157 3HZ LYS+ 132 16.583-7.359 2.413 1.00 0.00 ATOM 158 QZ LYS+ 132 16.671-7.651 1.484 1.00 0. 00 ATOM 159 C LYS+ 132 14.645-1.872 1.373 1. 00 0.00 ATOM 160 O LYS+ 132 14.501-2.874 0. 672 1.00 0.00

ATOM 161 N CYS 133 13.621-1.184 1.847 1.00 0.00 ATOM 162 H CYS 133 13.791-0.393 2.400 1.00 0.00 ATOM 163 CA CYS 133 12.248-1.578 1.559 1.00 0.00 ATOM 164 HA CYS 133 12.251-2.632 1.326 1.00 0.00 ATOM 165 CB CYS 133 11.349-1.337 2.774 1.00 0.00 ATOM 166 1HB CYS 133 10. 359-1. 076 2.429 1.00 0.00 ATOM 167 2HB CYS 133 11.748-0.514 3.345 1.00 0.00 ATOM 168 QB CYS 133 11.053-0.795 2.887 1.00 0.00 ATOM 169 SG CYS 133 11.184-2.759 3.904 1.00 0.00 ATOM 170 C CYS 133 11.716-0.810 0.356 1.00 0.00 ATOM 171 O CYS 133 12.185 0.279 0.056 1.00 0.00 ATOM 172 N LYS+ 134 10.729-1.377-0.321 1.00 0.00 ATOM 173 H LYS+ 134 10. 381-2. 246-0.026 1.00 0.00 ATOM 174 CA LYS+ 134 10.133-0.736-1.483 1.00 0.00 ATOM 175 HA LYS+ 134 10.817 0.025-1.832 1.00 0.00 ATOM 176 CB LYS+ 134 9.897-1.756-2.603 1.00 0. 00 ATOM 177 1HB LYS+ 134 9.218-2.515-2.242 1.00 0.00 ATOM 178 2HB LYS+ 134 10. 840-2. 218-2.856 1.00 0.00 ATOM 179 QB LYS+ 134 10.029-2.367-2.549 1.00 0.00 ATOM 180 CG LYS+ 134 9.307-1.149-3.868 1.00 0.00 ATOM 181 1HG LYS+ 134 9.715-0.156-4.002 1.00 0.00 ATOM 182 2HG LYS+ 134 8.234-1.085-3.760 1.00 0.00 ATOM 183 QG LYS+ 134 8.974-0.621-3.881 1.00 0.00 ATOM 184 CD LYS+ 134 9.630-1.985-5.097 1.00 0.00 ATOM 185 1HD LYS+ 134 10. 071-2. 919-4.781 1.00 0.00 ATOM 186 2HD LYS+ 134 10. 336-1. 443-5.712 1.00 0.00 ATOM 187 QD LYS+ 134 10. 203-2. 181-5.247 1.00 0.00 ATOM 188 CE LYS+ 134 8.384-2.276-5.920 1.00 0.00 ATOM 189 1HE LYS+ 134 8.641-2.977-6.703 1.00 0.00 ATOM 190 2HE LYS+ 134 8.039-1.354-6.366 1.00 0.00 ATOM 191 QE LYS+ 134 8.340-2.166-6.535 1.00 0.00 ATOM 192 NZ LYS+ 134 7.289-2.853-5.090 1.00 0.00 ATOM 193 1HZ LYS+ 134 6.568-2.125-4.889 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.667-3.204-4.187 1.00 0.00 ATOM 195 3HZ LYS+ 134 6.833-3.642-5.592 1.00 0.00 ATOM 196 QZ LYS+ 134 7.022-2.991-4.890 1.00 0.00 ATOM 197 C LYS+ 134 8.823-0.081-1.087 1.00 0.00 ATOM 198 O LYS+ 134 7.877-0.763-0.703 1.00 0.00 ATOM 199 N PHE 135 8.778 1.235-1.172 1.00 0.00 ATOM 200 H PHE 135 9.570 1.722-1.482 1.00 0.00 ATOM 201 CA PHE 135 7.584 1.981-0.807 1.00 0.00 ATOM 202 HA PHE 135 7.027 1.395-0.091 1.00 0.00 ATOM 203. CB PHE 135 7.987 3.310-0.164 1.00 0.00 ATOM 204 1HB PHE 135 8.315 3.985-0.942 1.00 0.00 ATOM 205 2HB PHE 135 8.807 3.134 0.514 1.00 0.00 ATOM 206 QB PHE 135 8.561 3.559-0.214 1.00 0.00 ATOM 207 QD PHE 135 6.782 4.081 0.701 1.00 0.00 ATOM 208 QE PHE 135 5.036 5.237 1.990 1.00 0.00 ATOM 209 QR PHE 135 5.559 4.891 1.604 1.00 0.00 ATOM 210 CG PHE 135 6.902 4.003 0.614 1.00 0.00 ATOM 211 CD1 PHE 135 7.057 5. 327 0.989 1.00 0.00 ATOM 212 1HD PHE 135 7.959 5.854 0. 709 1.00 0.00 ATOM 213 CE1 PHE 135 6.079 5.979 1.712 1.00 0. 00 ATOM 214 1HE PHE 135 6.215 7.012 1.998 1.00 0.00 ATOM 215 CZ PHE 135 4.927 5.309 2.069 1.00 0.00 ATOM 216 HZ PHE 135 4.158 5.816 2.636 1.00 0.00 ATOM 217 CE2 PHE 135 4.759 3.990 1.702 1.00 0.00 ATOM 218 2HE PHE 135 3.858 3.463 1.983 1.00 0.00 ATOM 219 CD2 PHE 135 5.741 3.342 0.979 1.00 0.00 ATOM 220 2HD PHE 135 5.605 2.309 0.694 1.00 0.00 ATOM 221 C PHE 135 6.715 2.236-2.025 1.00 0.00 ATOM 222 O PHE 135 7.167 2.803-3.016 1.00 0.00 ATOM 223 N LEU 136 5.466 1.815-1.939 1.00 0.00 ATOM 224 H LEU 136 5.167 1.369-1.114 1.00 0.00 ATOM 225 CA LEU 136 4.517 1.998-3.017 1.00 0.00 ATOM 226 HA LEU 136 5.034 2.473-3.839 1.00 0.00 ATOM 227 CB LEU 136 3.954 0.656-3.484 1.00 0.00 ATOM 228 1HB LEU 136 3.205 0.849-4.238 1.00 0.00 ATOM 229 2HB LEU 136 3.473 0.180-2.640 1.00 0.00 ATOM 230 QB LEU 136 3.339 0.514-3.439 1.00 0.00 ATOM 231 CG LEU 136 4.983-0.314-4.065 1.00 0.00 ATOM 232 HG LEU 136 5.838 0.246-4.413 1.00 0.00

ATOM 233 QD1 LEU 136 5.565-1.515-2.744 1.00 0.00 ATOM 234 QD2 LEU 136 4.250-1.242-5.528 1.00 0.00 ATOM 235 CD1 LEU 136 5.455-1.285-2.998 1.00 0.00 ATOM 236 1HD1 LEU 136 5.162-2.289-3.268 1.00 0.00 ATOM 237 2HD1 LEU 136 5.005-1.022-2.051 1.00 0.00 ATOM 238 3HD1 LEU 136 6.530-1.232-2.911 1.00 0.00 ATOM 239 CD2 LEU 136 4.392-1.065-5.248 1.00 0.00 ATOM 240 1HD2 LEU 136 5.054-0.982-6.096 1.00 0.00 ATOM 241 2HD2 LEU 136 3.431-0.638-5.499 1.00 0.00 ATOM 242 3HD2 LEU 136 4.265-2.105-4.988 1.00 0.00 ATOM 243 QQD LEU 136 4. 907-1.378-4.136 1.00 0.00 ATOM 244 C LEU 136 3.395 2.906-2.549 1.00 0.00 ATOM 245 O LEU 136 2.297 2.449-2.237 1.00 0.00 ATOM 246 N HIS+ 137 3.686 4.195-2.495 1.00 0.00 ATOM 247 H HIS+ 137 4.583 4.491-2.752 1.00 0.00 ATOM 248 CA HIS+ 137 2.713 5. 182-2. 062 1.00 0.00 ATOM 249 HA HIS+ 137 1.998 4.695-1.409 1.00 0.00 ATOM 250 CB HIS+ 137 3.416 6.318-1.304 1.00 0.00 ATOM 251 1HB HIS+ 137 4.023 6.880-1.999 1.00 0.00 ATOM 252 2HB HIS+ 137 4.055 5.891-0.546 1.00 0.00 ATOM 253 QB HIS+ 137 4.039 6.385-1.273 1.00 0.00 ATOM 254 CG HIS+ 137 2.485 7.279-0.625 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.534 8.016-1.296 1.00 0.00 ATOM 256 CD2 HIS+ 137 2.354 7.605 0.678 1.00 0.00 ATOM 257 1HD HIS+ 137 1.384 8.011-2.268 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.856 8.748-0.431 1.00 0.00 ATOM 259 NE2 HIS+ 137 1.330 8.516 0.782 1.00 0.00 ATOM 260 2HD HIS+ 137 2.943 7.212 1.497 1.00 0.00 ATOM 261 1HE HIS+ 137 0.047 9.422-0.673 1.00 0.00 ATOM 262 2HE HIS+ 137 0.812 8.664 1.611 1.00 0.00 ATOM 263 C HIS+ 137 1.996 5.740-3.278 1.00 0.00 ATOM 264 O HIS+ 137 2.491 6. 658-3. 933 1.00 0.00 ATOM 265 N GLN 138 0.838 5.183-3.590 1. 00 0.00 ATOM 266 H GLN 138 0.483 4.447-3.034 1.00 0.00 ATOM 267 CA GLN 138 0.082 5.640-4.743 1. 00 0.00 ATOM 268 HA GLN 138 0.419 6.639-4.978 1.00 0.00 ATOM 269 CB GLN 138 0.345 4.734-5.950 1.00 0.00 ATOM 270 1HB GLN 138-0.483 4.820-6.637 1.00 0.00 ATOM 271 2HB GLN 138 0.417 3.711-5.610 1. 00 0.00 ATOM 272 QB GLN 138-0.033 4.265-6.124 1. 00 0.00 ATOM 273 CG GLN 138 1.626 5.077-6.700 1. 00 0.00 ATOM 274 1HG GLN 138 1.947 6.066-6.404 1. 00 0.00 ATOM 275 2HG GLN 138 1.422 5.069-7.761 1.00 0.00 ATOM 276 QG GLN 138 1.684 5.567-7.083 1.00 0.00 ATOM 277 CD GLN 138 2.749 4.098-6.417 1.00 0.00 ATOM 278 OE1 GLN 138 2.551 2.885-6.464 1.00 0.00 ATOM 279 NE2 GLN 138 3.934 4.618-6.116 1.00 0.00 ATOM 280 1HE2 GLN 138 4.020 5.595-6.091 1.00 0.00 ATOM 281 2HE2 GLN 138 4.675 4. 005-5.931 1.00 0. 00 ATOM 282 QE2 GLN 138 4.347 4.800-6.011 1.00 0.00 ATOM 283 C GLN 138-1.403 5.689-4.435 1.00 0.00 ATOM 284 O GLN 138-1.933 4.838-3.719 1.00 0.00 ATOM 285 N GLU 139-2.067 6.689-4.984 1.00 0.00 ATOM 286 H GLU 139-1.592 7.330-5.544 1.00 0.00 ATOM 287 CA GLU 139-3.485 6.863-4.777 1.00 0.00 ATOM 288 HA GLU 139-3.747 6.396-3.840 1.00 0.00 ATOM 289 CB GLU 139-3. 830 8.353-4.712 1.00 0.00 ATOM 290 1HB GLU 139-4.489 8.523-3.872 1.00 0.00 ATOM 291 2HB GLU 139-4.341 8.633-5.620 1.00 0.00 ATOM 292 QB GLU 139-4.415 8.578-4.746 1.00 0.00 ATOM 293 CG GLU 139-2.617 9.257-4.551 1.00 0.00 ATOM 294 1HG GLU 139-2.297 9.590-5.528 1.00 0.00 ATOM 295 2HG GLU 139-1.822 8.696-4.084 1.00 0.00 ATOM 296 QG GLU 139-2.060 9.143-4.806 1.00 0.00 ATOM 297 CD GLU 139-2.909 10.473-3.700 1.00 0.00 ATOM 298 OE1 GLU 139-4.100 10.738-3.437 1.00 0.00 ATOM 299 OE2 GLU 139-1.948 11.149-3.286 1.00 0.00 ATOM 300 C GLU 139-4.263 6.196-5.900 1. 00 0. 00 ATOM 301 O GLU 139-3. 784 6.082-7.031 1.00 0.00 ATOM 302 N ARG+ 140-5.454 5.752-5.571 1.00 0.00 ATOM 303 H ARG+ 140-5.761 5.871-4.649 1.00 0.00 ATOM 304 CA ARG+ 140-6.332 5. 090-6. 522 1.00 0.00

ATOM 305 HA ARG+ 140-6.020 5.365-7.520 1.00 0.00 ATOM 306 CB ARG+ 140-6.249 3.567-6.361 1.00 0.00 ATOM 307 1HB ARG+ 140-6.866 3.276-5.522 1.00 0.00 ATOM 308 2HB ARG+ 140-5.226 3.293-6.155 1.00 0.00 ATOM 309 QB ARG+ 140-6.046 3.284-5.839 1.00 0.00 ATOM 310 CG ARG+ 140-6.713 2.794-7.583 1.00 0.00 ATOM 311 1HG ARG+ 140-7.437 3.394-8.123 1.00 0.00 ATOM 312 2HG ARG+ 140-7. 178 1.874-7.262 1.00 0.00 ATOM 313 QG ARG+ 140-7.308 2.634-7.693 1.00 0.00 ATOM 314 CD ARG+ 140-5.556 2.467-8.512 1.00 0.00 ATOM 315 1HD ARG+ 140-5.037 3.383-8.753 1.00 0.00 ATOM 316 2HD ARG+ 140-5.955 2.034-9.420 1.00 0.00 ATOM 317 QD ARG+ 140-5.496 2.708-9.087 1.00 0.00 ATOM 318 NE ARG+ 140-4.613 1.524-7.907 1.00 0.00 ATOM 319 HE ARG+ 140-4.900 0.585-7.839 1.00 0.00 ATOM 320 CZ ARG+ 140-3. 402 1.864-7.461 1.00 0.00 ATOM 321 NH1 ARG+ 140-3.006 3.132-7.515 1.00 0.00 ATOM 322 1HH1 ARG+ 140-3.618 3.835-7.889 1.00 0.00 ATOM 323 2HH1 ARG+ 140-2.100 3.393-7.182 1. 00 0.00 ATOM 324 QH1 ARG+ 140-2.859 3.614-7.536 1.00 0.00 ATOM 325 NH2 ARG+ 140-2.596 0.939-6.949 1.00 0.00 ATOM 326 1HH2 ARG+ 140-2.895-0.016-6.897 1.00 0.00 ATOM 327 2HH2 ARG+ 140-1.686 1.193-6.614 1.00 0.00 ATOM 328 QH2 ARG+ 140-2.291 0.588-6.756 1.00 0.00 ATOM 329 C ARG+ 140-7.761 5.562-6.297 1. 00 0.00 ATOM 330 O ARG+ 140-8.552 4.879-5.649 1.00 0.00 ATOM 331 N MET 141-8.087 6.739-6.827 1.00 0.00 ATOM 332 H MET 141-7. 410 7.237-7.330 1.00 0.00 ATOM 333 CA MET 141-9.426 7.313-6.676 1. 00 0.00 ATOM 334 HA MET 141-9.720 7.192-5.645 1.00 0.00 ATOM 335 CB MET 141-9.401 8.809-7.016 1.00 0.00 ATOM 336 1HB MET 141-9.427 8.918-8.091 1.00 0.00 ATOM 337 2HB MET 141-8.483 9.236-6.642 1.00 0.00 ATOM 338 QB MET 141-8.955 9.077-7.367 1.00 0.00 ATOM 339 CG MET 141-10.566 9.596-6.431 1.00 0.00 ATOM 340 1HG MET 141-11.179 8.925-5.847 1.00 0.00 ATOM 341 2HG MET 141-11.154 9.997-7.245 1.00 0.00 ATOM 342 QG MET 141-11.167 9.461-6.546 1.00 0.00 ATOM 343 SD MET 141-10.034 10.959-5.379 1.00 0.00 ATOM 344 QE MET 141-9.076 12.238-6.821 1.00 0.00 ATOM 345 CE MET 141-9.236 12.024-6.579 1. 00 0.00 ATOM 346 1HE MET 141-8.690 12.802-6.065 1.00 0.00 ATOM 347 2HE MET 141-9.984 12.472-7.218 1.00 0.00 ATOM 348 3HE MET 141-8.552 11.442-7.180 1.00 0.00 ATOM 349 C MET 141-10.443 6.588-7.563 1.00 0.00 ATOM 350 O MET 141-11.387 7.192-8.072 1.00 0.00 ATOM 351 N ASP 142-10.234 5.295-7.739 1.00 0.00 ATOM 352 H ASP 142-9.463 4.878-7.308 1.00 0. 00 ATOM 353 CA ASP 142-11.098 4.473-8.556 1.00 0.00 ATOM 354 HA ASP 142-11.838 5.112-9.013 1.00 0.00 ATOM 355 CB ASP 142-10.277 3.791-9.652 1.00 0.00 ATOM 356 1HB ASP 142-10.928 3.552-10.470 1.00 0.00 ATOM 357 2HB ASP 142-9.851 2.880-9.261 1.00 0.00 ATOM 358 QB ASP 142-10.390 3.216-9.866 1.00 0.00 ATOM 359 CG ASP 142-9.150 4.659-10.175 1.00 0.00 ATOM 360 OD1 ASP 142-9.360 5.359-11.184 1.00 0.00 ATOM 361 OD2 ASP 142-8.054 4.639-9.573 1.00 0.00 ATOM 362 C ASP 142-11.796 3.418-7.711 1.00 0. 00 ATOM 363 O ASP 142-12.967 3.104-7.927 1.00 0.00 ATOM 364 N VAL 143-11.067 2.857-6.752 1.00 0.00 ATOM 365 H VAL 143-10.137 3.138-6.629 1.00 0.00 ATOM 366 CA VAL 143-11.622 1.823-5.889 1.00 0.00 ATOM 367 HA VAL 143-12.597 1.563-6.277 1.00 0.00 ATOM 368 CB VAL 143-10.744 0.551-5.896 1.00 0.00 ATOM 369 HB VAL 143-10.053 0.612-5.065 1.00 0.00 ATOM 370 QG1 VAL 143-11. 798-0.991-5.668 1.00 0.00 ATOM 371 QG2 VAL 143-9. 742 0.428-7.485 1.00 0.00 ATOM 372 CG1 VAL 143-11.597-0.695-5.710 1.00 0.00 ATOM 373 1HG1 VAL 143-11.827-0.823-4.663 1.00 0.00 ATOM 374 2HG1 VAL 143-11. 053-1. 558-6.067 1.00 0.00 ATOM 375 3HG1 VAL 143-12.514-0.591-6.272 1.00 0.00 ATOM 376 CG2 VAL 143-9.933 0.452-7.181 1.00 0.00

ATOM 377 1HG2 VAL 143-10.251 1.223-7.867 1.00 0.00 ATOM 378 2HG2 VAL 143-10.089-0.517-7.631 1.00 0.00 ATOM 379 3HG2 VAL 143-8.885 0.580-6.956 1.00 0.00 ATOM 380 QQG VAL 143-10.770-0.281-6.576 1.00 0.00 ATOM 381 C VAL 143-11.785 2.336-4.456 1.00 0.00 ATOM 382 O VAL 143-11. 084 3.253-4.031 1.00 0.00 ATOM 383 N CYS 144-12.722 1.747-3.718 1.00 0.00 ATOM 384 H CYS 144-13.252 1.025-4.112 1.00 0.00 ATOM 385 CA CYS 144-12.988 2.152-2.338 1.00 0.00 ATOM 386 HA CYS 144-12.119 2.677-1.962 1.00 0.00 ATOM 387 CB CYS 144-14.200 3.085-2.290 1.00 0.00 ATOM 388 1HB CYS 144-14. 410 3.335-1.261 1.00 0.00 ATOM 389 2HB CYS 144-15.053 2.572-2.709 1.00 0.00 ATOM 390 QB CYS 144-14.732 2.953-1.985 1.00 0.00 ATOM 391 SG CYS 144-13.990 4.645-3.210 1.00 0.00 ATOM 392 C CYS 144-13.250 0.940-1.458 1.00 0.00 ATOM 393 O CYS 144-14.393 0.505-1.315 1.00 0.00 ATOM 394 N GLU 145-12.194 0.399-0.870 1.00 0.00 ATOM 395 H GLU 145-11.306 0.788-1.021 1.00 0.00 ATOM 396 CA GLU 145-12.318-0.767-0.011 1.00 0.00 ATOM 397 HA GLU 145-13.357-1.056 0.001 1.00 0.00 ATOM 398 CB GLU 145-11.498-1.923-0.578 1.00 0. 00 ATOM 399 1HB GLU 145-11.216-2.581 0.229 1.00 0.00 ATOM 400 2HB GLU 145-10.602-1.528-1.037 1.00 0.00 ATOM 401 QB GLU 145-10.909-2.055-0.404 1.00 0.00 ATOM 402 CG GLU 145-12.260-2.736-1.610 1.00 0.00 ATOM 403 1HG GLU 145-11.788-3.702-1.715 1.00 0.00 ATOM 404 2HG GLU 145-12.231-2.215-2.556 1.00 0.00 ATOM 405 QG GLU 145-12.010-2.959-2.136 1.00 0.00 ATOM 406 CD GLU 145-13.703-2.939-1.213 1.00 0.00 ATOM 407 OE1 GLU 145-14.593-2.681-2.040 1.00 0.00 ATOM 408 OE2 GLU 145-13.948-3.323-0.048 1.00 0.00 ATOM 409 C GLU 145-11.881-0.465 1.413 1.00 0.00 ATOM 410 O GLU 145-11.472 0.653 1.726 1.00 0.00 ATOM 411 N THR 146-11.982-1.474 2.266 1.00 0.00 ATOM 412 H THR 146-12.321-2.335 1.945 1.00 0.00 ATOM 413 CA THR 146-11.613-1.349 3.664 1.00 0.00 ATOM 414 HA THR 146-11.991-0.404 4.029 1.00 0.00 ATOM 415 CB THR 146-12.262-2.487 4.455 1.00 0.00 ATOM 416 HB THR 146-11.584-3.329 4.475 1.00 0.00 ATOM 417 QG2 THR 146-12.671-2.038 6.229 1.00 0.00 ATOM 418 OG1 THR 146-13. 466-2.901 3.828 1.00 0.00 ATOM 419 1HG THR 146-14.178-2.910 4.476 1.00 0.00 ATOM 420 CG2 THR 146-12.592-2.125 5.887 1.00 0.00 ATOM 421 1HG2 THR 146-11.696-2.173 6.487 1.00 0.00 ATOM 422 2HG2 THR 146-13.322-2.819 6.278 1.00 0.00 ATOM 423 3HG2 THR 146-12.994-1.121 5.923 1.00 0.00 ATOM 424 C THR 146-10.095-1.378 3.831 1.00 0.00 ATOM 425 O THR 146-9.367-1.770 2.915 1.00 0.00 ATOM 426 N HIS+ 147-9.633-0.969 5.009 1.00 0.00 ATOM 427 H HIS+ 147-10.277-0.674 5.692 1.00 0.00 ATOM 428 CA HIS+ 147-8.206-0.944 5.331 1.00 0.00 ATOM 429 HA HIS+ 147-7.726-0.223 4.687 1.00 0.00 ATOM 430 CB HIS+ 147-8.023-0.515 6.792 1.00 0.00 ATOM 431 1HB HIS+ 147-8.034-1.396 7.418 1.00 0.00 ATOM 432 2HB HIS+ 147-8.844 0.127 7.075 1.00 0.00 ATOM 433 QB HIS+ 147-8.439-0.635 7.246 1.00 0.00 ATOM 434 CG HIS+ 147-6.750 0.226 7.064 1.00 0.00 ATOM 435 ND1 HIS+ 147-6.696 1.597 7.206 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.483-0.220 7.240 1.00 0.00 ATOM 437 1HD HIS+ 147-7.459 2.215 7.128 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.451 1.963 7.459 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.695 0.880 7.487 1.00 0.00 ATOM 440 2HD HIS+ 147-5.148-1.248 7.172 1.00 0.00 ATOM 441 1HE HIS+ 147-5.110 2.976 7.617 1.00 0.00 ATOM 442 2HE HIS+ 147-3.714 0.879 7.523 1.00 0.00 ATOM 443 C HIS+ 147-7.565-2.316 5.116 1.00 0.00 ATOM 444 O HIS+ 147-6. 405-2. 417 4.718 1.00 0. 00 ATOM 445 N LEU 148-8.329-3.369 5.387 1.00 0.00 ATOM 446 H LEU 148-9.245-3.224 5.701 1.00 0.00 ATOM 447 CA LEU 148-7.840-4.733 5.235 1.00 0.00 ATOM 448 HA LEU 148-6.851-4.777 5.666 1.00 0.00

ATOM 449 CB LEU 148-8. 751-5.705 5.991 1.00 0.00 ATOM 450 1HB LEU 148-9.773-5.501 5.710 1.00 0.00 ATOM 451 2HB LEU 148-8.643-5.517 7.050 1.00 0. 00 ATOM 452 QB LEU 148-9.208-5.509 6.380 1.00 0.00 ATOM 453 CG LEU 148-8.473-7.186 5.736 1.00 0.00 ATOM 454 HG LEU 148-8.157-7.312 4.711 1.00 0.00 ATOM 455 QD1 LEU 148-7.090-7.806 6.848 1.00 0.00 ATOM 456 QD2 LEU 148-10. 030-8. 208 5.995 1.00 0. 00 ATOM 457 CD1 LEU 148-7. 354-7.686 6. 635 1.00 0.00 ATOM 458 1HD1 LEU 148-7.258-7.034 7.490 1.00 0.00 ATOM 459 2HD1 LEU 148-6.426-7.697 6. 083 1.00 0.00 ATOM 460 3HD1 LEU 148-7.584-8.687 6.971 1.00 0.00 ATOM 461 CD2 LEU 148-9.732-8.011 5.946 1.00 0.00 ATOM 462 1HD2 LEU 148-10.523-7.629 5.318 1.00 0.00 ATOM 463 2HD2 LEU 148-10.033-7.952 6.981 1.00 0.00 ATOM 464 3HD2 LEU 148-9.533-9.041 5.688 1.00 0.00 ATOM 465 QQD LEU 148-8.560-8.007 6.422 1.00 0.00 ATOM 466 C LEU 148-7.749-5.136 3.766 1.00 0.00 ATOM 467 O LEU 148-6.844-5.874 3.377 1.00 0.00 ATOM 468 N HIS+ 149-8.683-4.658 2.950 1.00 0.00 ATOM 469 H HIS+ 149-9.382-4.074 3.308 1.00 0.00 ATOM 470 CA HIS+ 149-8.680-4.992 1.531 1.00 0.00 ATOM 471 HA HIS+ 149-8.629-6.070 1.461 1.00 0.00 ATOM 472 CB HIS+ 149-9.966-4.526 0.853 1.00 0.00 ATOM 473 1HB HIS+ 149-9.726-4.106-0.114 1.00 0.00 ATOM 474 2HB HIS+ 149-10.438-3.770 1.463 1.00 0.00 ATOM 475 QB HIS+ 149-10.082-3.938 0.674 1.00 0.00 ATOM 476 CG HIS+ 149-10.947-5.640 0.646 1.00 0. 00 ATOM 477 ND1 HIS+ 149-12.277-5.436 0.341 1.00 0.00 ATOM 478 CD2 HIS+ 149-10.781-6.984 0.704 1.00 0.00 ATOM 479 1HD HIS+ 149-12.719-4.556 0.216 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.884-6.604 0.223 1.00 0.00 ATOM 481 NE2 HIS+ 149-11.999-7.558 0.438 1.00 0.00 ATOM 482 2HD HIS+ 149-9.859-7.507 0.919 1.00 0.00 ATOM 483 1HE HIS+ 149-13.929-6.752-0.014 1.00 0.00 ATOM 484 2HE HIS+ 149-12.170-8.519 0.351 1.00 0.00 ATOM 485 C HIS+ 149-7.451-4.419 0.843 1.00 0.00 ATOM 486 O HIS+ 149-6.745-5.140 0.143 1.00 0.00 ATOM 487 N TRP 150-7.170-3.137 1.072 1.00 0.00 ATOM 488 H TRP 150-7.756-2.611 1.660 1.00 0.00 ATOM 489 CA TRP 150-5. 982-2.510 0.490 1.00 0.00 ATOM 490 HA TRP 150-6.003-2.658-0.581 1.00 0.00 ATOM 491 CB TRP 150-5.921-1.016 0.807 1.00 0.00 ATOM 492 1HB TRP 150-4.964-0.632 0.482 1.00 0.00 ATOM 493 2HB TRP 150-6.005-0.882 1.875 1.00 0.00 ATOM 494 QB TRP 150-5. 485-0.757 1.178 1.00 0.00 ATOM 495 CG TRP 150-6. 989-0. 190 0. 162 1.00 0.00 ATOM 496 CD1 TRP 150-7.435 1.026 0.589 1.00 0.00 ATOM 497 CD2 TRP 150-7.737-0.498-1.019 1.00 0. 00 ATOM 498 CE3 TRP 150-7. 753-1.574-1.911 1.00 0.00 ATOM 499 CE2 TRP 150-8.616 0.577-1.241 1.00 0.00 ATOM 500 NE1 TRP 150-8. 411 1.491-0.249 1.00 0. 00 ATOM 501 HD TRP 150-7.062 1.536 1.465 1.00 0.00 ATOM 502 3HE TRP 150-7. 096-2.419-1.778 1.00 0.00 ATOM 503 CZ3 TRP 150-8.629-1.543-2.973 1.00 0.00 ATOM 504 CZ2 TRP 150-9.496 0.607-2.311 1.00 0.00 ATOM 505 1HE TRP 150-8.887 2.344-0.152 1.00 0.00 ATOM 506 3HZ TRP 150-8.660-2.366-3.670 1.00 0.00 ATOM 507 CH2 TRP 150-9.489-0.459-3.164 1.00 0.00 ATOM 508 2HZ TRP 150-10. 171 1.437-2.474 1.00 0. 00 ATOM 509 HH TRP 150-10.160-0.478-4.010 1.00 0.00 ATOM 510 C TRP 150-4.744-3.184 1.033 1.00 0.00 ATOM 511 O TRP 150-3.762-3.339 0.324 1.00 0.00 ATOM 512 N HIS+ 151-4.815-3.610 2.290 1.00 0.00 ATOM 513 H HIS+ 151-5.644-3.470 2.796 1.00 0.00 ATOM 514 CA HIS+ 151-3.708-4.310 2.922 1.00 0.00 ATOM 515 HA HIS+ 151-2.846-3.660 2.913 1.00 0. 00 ATOM 516 CB HIS+ 151-4.077-4.664 4.377 1.00 0.00 ATOM 517 1HB HIS+ 151-5.006-5.218 4.371 1.00 0.00 ATOM 518 2HB HIS+ 151-4.222-3.749 4.929 1.00 0. 00 ATOM 519 QB HIS+ 151-4.614-4.484 4.650 1.00 0.00 ATOM 520 CG HIS+ 151-3.060-5.487 5.124 1.00 0.00

ATOM 521 ND1 HIS+ 151-2.626-5. 167 6.392 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.424-6.640 4.797 1.00 0.00 ATOM 523 1HD HIS+ 151-2.900-4.380 6.912 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.772-6.085 6.810 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.633-6.990 5.862 1.00 0.00 ATOM 526 2HD HIS+ 151-2.516-7. 175 3.859 1.00 0.00 ATOM 527 1HE HIS+ 151-1.274-6.093 7.769 1.00 0.00 ATOM 528 2HE HIS+ 151-1.178-7.851 5.970 1.00 0.00 ATOM 529 C HIS+ 151-3.405-5.567 2.118 1.00 0.00 ATOM 530 O HIS+ 151-2.249-5. 879 1.849 1.00 0.00 ATOM 531 N THR 152-4.461-6.269 1.728 1.00 0.00 ATOM 532 H THR 152-5.357-5. 954 1.969 1.00 0.00 ATOM 533 CA THR 152-4.327-7.483 0.941 1.00 0.00 ATOM 534 HA THR 152-3.614-8. 123 1.438 1.00 0.00 ATOM 535 CB THR 152-5.671-8.211 0.847 1.00 0.00 ATOM 536 HB THR 152-6. 313-7.671 0. 165 1.00 0.00 ATOM 537 QG2 THR 152-5.523-9. 972 0.221 1.00 0.00 ATOM 538 OG1 THR 152-6.306-8.262 2.114 1.00 0.00 ATOM 539 1HG THR 152-6.333-7.380 2.503 1.00 0.00 ATOM 540 CG2 THR 152-5.551-9. 633 0.342 1.00 0.00 ATOM 541 1HG2 THR 152-4.714-9.705-0.338 1.00 0.00 ATOM 542 2HG2 THR 152-6.459-9.909-0.175 1.00 0.00 ATOM 543 3HG2 THR 152-5.396-10.300 1.177 1.00 0.00 ATOM 544 C THR 152-3.795-7.171-0.447 1.00 0.00 ATOM 545 O THR 152-2.807-7.759-0. 851 1.00 0.00 ATOM 546 N VAL 153-4.439-6.240-1.160 1.00 0.00 ATOM 547 H VAL 153-5.221-5.791-0.768 1.00 0.00 ATOM 548 CA VAL 153-3.997-5.862-2.506 1.00 0.00 ATOM 549 HA VAL 153-4.073-6.734-3.136 1.00 0.00 ATOM 550 CB VAL 153-4.876-4.742-3.108 1.00 0.00 ATOM 551 HB VAL 153-4. 683-3.829-2.564 1.00 0.00 ATOM 552 QG1 VAL 153-4.445-4.456-4.916 1.00 0.00 ATOM 553 QG2 VAL 153-6.701-5.165-2.932 1.00 0.00 ATOM 554 CG1 VAL 153-4.528-4.510-4.570 1.00 0.00 ATOM 555 1HG1 VAL 153-3.561-4.944-4.783 1.00 0.00 ATOM 556 2HG1 VAL 153-4.499-3.450-4.769 1.00 0.00 ATOM 557 3HG1 VAL 153-5.275-4.974-5.195 1.00 0.00 ATOM 558 CG2 VAL 153-6.352-5.083-2.965 1.00 0.00 ATOM 559 1HG2 VAL 153-6.536-6.060-3.387 1.00 0.00 ATOM 560 2HG2 VAL 153-6.944-4.348-3.489 1.00 0.00 ATOM 561 3HG2 VAL 153-6. 622-5.086-1.919 1.00 0.00 ATOM 562 QQG VAL 153-5.573-4.811-3.924 1.00 0.00 ATOM 563 C VAL 153-2.543-5.414-2.480 1.00 0.00 ATOM 564 O VAL 153-1.735-5.810-3.313 1.00 0.00 ATOM 565 N ALA 154-2.217-4.602-1.500 1.00 0.00 ATOM 566 H ALA 154-2.910-4.327-0. 854 1.00 0.00 ATOM 567 CA ALA 154-0.860-4.117-1.338 1.00 0.00 ATOM 568 HA ALA 154-0.559-3.623-2.249 1.00 0. 00 ATOM 569 QB ALA 154-0.809-2.876 0.065 1.00 0.00 ATOM 570 CB ALA 154-0.819-3.114-0.204 1.00 0.00 ATOM 571 1HB ALA 154-0.380-3.574 0.668 1.00 0.00 ATOM 572 2HB ALA 154-1.823-2.790 0.027 1.00 0.00 ATOM 573 3HB ALA 154-0.224-2.262-0.500 1.00 0.00 ATOM 574 C ALA 154 0.100-5.269-1. 053 1.00 0.00 ATOM 575 O ALA 154 1.158-5.388-1.677 1.00 0.00 ATOM 576 N LYS+ 155-0. 272-6.109-0. 094 1.00 0.00 ATOM 577 H LYS+ 155-1.124-5.954 0.371 1.00 0.00 ATOM 578 CA LYS+ 155 0.551-7.245 0.295 1.00 0.00 ATOM 579 HA LYS+ 155 1.533-6. 865 0.553 1.00 0.00 ATOM 580 CB LYS+ 155-0.044-7.952 1.517 1.00 0.00 ATOM 581 1HB LYS+ 155-0.948-8.462 1.214 1.00 0.00 ATOM 582 2HB LYS+ 155-0.295-7.209 2.260 1.00 0.00 ATOM 583 QB LYS+ 155-0.622-7.836 1.737 1.00 0.00 ATOM 584 CG LYS+ 155 0.891-8.971 2.155 1.00 0.00 ATOM 585 1HG LYS+ 155 1.330-8.535 3.041 1.00 0.00 ATOM 586 2HG LYS+ 155 1.670-9.222 1.450 1.00 0.00 ATOM 587 QG LYS+ 155 1.500-8.879 2.245 1.00 0.00 ATOM 588 CD LYS+ 155 0.149-10.243 2.544 1.00 0.00 ATOM 589 1HD LYS+ 155-0.375-10.621 1.679 1.00 0.00 ATOM 590 2HD LYS+ 155-0.564-10.007 3.322 1.00 0.00 ATOM 591 QD LYS+ 155-0.470-10.314 2.500 1.00 0.00 ATOM 592 CE LYS+ 155 1.102-11.314 3.059 1.00 0.00

ATOM 593 1HE LYS+ 155 0.562-11.961 3.736 1.00 0.00 ATOM 594 2HE LYS+ 155 1.909-10.833 3.592 1.00 0.00 ATOM 595 QE LYS+ 155 1.235-11.397 3.664 1.00 0.00 ATOM 596 NZ LYS+ 155 1.674-12.137 1.954 1.00 0.00 ATOM 597 1HZ LYS+ 155 0.915-12.490 1.337 1.00 0.00 ATOM 598 2HZ LYS+ 155 2.193-12.950 2.343 1.00 0.00 ATOM 599 3HZ LYS+ 155 2.337-11.562 1.377 1.00 0.00 ATOM 600 QZ LYS+ 155 1.815-12.334 1.685 1.00 0.00 ATOM 601 C LYS+ 155 0.707-8.239-0.845 1.00 0.00 ATOM 602 0 LYS+ 155 1.813-8.706-1.086 1.00 0.00 ATOM 603 N GLU 156-0.386-8.575-1.532 1.00 0.00 ATOM 604 H GLU 156-1.259-8.179-1.290 1.00 0.00 ATOM 605 CA GLU 156-0.308-9.533-2.634 1.00 0.00 ATOM 606 HA GLU 156 0.145-10.430-2.236 1.00 0.00 ATOM 607 CB GLU 156-1.692-9.899-3.196 1.00 0.00 ATOM 608 1HB GLU 156-2.228-10.470-2.453 1.00 0.00 ATOM 609 2HB GLU 156-1.555-10.514-4.074 1.00 0.00 ATOM 610 QB GLU 156-1.892-10.492-3.264 1.00 0. 00 ATOM 611 CG GLU 156-2.553-8.715-3.593 1.00 0.00 ATOM 612 1HG GLU 156-2.058-7.806-3.283 1.00 0.00 ATOM 613 2HG GLU 156-3.504-8.794-3.091 1.00 0.00 ATOM 614 QG GLU 156-2.781-8.300-3.187 1.00 0.00 ATOM 615 CD GLU 156-2.802-8.645-5.082 1.00 0.00 ATOM 616 OE1 GLU 156-2. 147-7.820-5.751 1.00 0.00 ATOM 617 OE2 GLU 156-3.652-9.412-5.575 1.00 0.00 ATOM 618 C GLU 156 0.598-9.010-3.741 1.00 0.00 ATOM 619 O GLU 156 1.435-9.748-4.238 1.00 0.00 ATOM 620 N THR 157 0.445-7.738-4.106 1.00 0.00 ATOM 621 H THR 157-0.241-7.190-3.662 1.00 0.00 ATOM 622 CA THR 157 1.277-7.134-5.146 1.00 0.00 ATOM 623 HA THR 157 1.074-7.655-6.071 1.00 0.00 ATOM 624 CB THR 157 0.913-5.651-5.316 1.00 0.00 ATOM 625 HB THR 157 0.922-5.178-4.344 1.00 0.00 ATOM 626 QG2 THR 157 2.089-4.703-6.426 1.00 0.00 ATOM 627 OG1 THR 157-0.385-5.506-5.867 1.00 0.00 ATOM 628 1HG THR 157-0.910-6.307-5.691 1.00 0.00 ATOM 629 CG2 THR 157 1.864-4.884-6.212 1.00 0.00 ATOM 630 1HG2 THR 157 2.294-4.061-5.662 1.00 0.00 ATOM 631 2HG2 THR 157 1.324-4.503-7.066 1.00 0.00 ATOM 632 3HG2 THR 157 2.651-5.543-6.549 1.00 0.00 ATOM 633 C THR 157 2.767-7.295-4.811 1.00 0.00 ATOM 634 O THR 157 3.593-7.553-5.687 1.00 0.00 ATOM 635 N CYS 158 3.108-7.148-3.537 1.00 0. 00 ATOM 636 H CYS 158 2.409-6.938-2.873 1.00 0.00 ATOM 637 CA CYS 158 4.495-7.290-3.103 1.00 0.00 ATOM 638 HA CYS 158 5.128-6.872-3.872 1.00 0.00 ATOM 639 CB CYS 158 4.717-6.508-1.812 1.00 0.00 ATOM 640 1HB CYS 158 5.583-6.895-1. 305 1.00 0.00 ATOM 641 2HB CYS 158 3.854-6.630-1.177 1.00 0.00 ATOM 642 QB CYS 158 4.718-6.763-1.241 1.00 0.00 ATOM 643 SG CYS 158 4.968-4.715-2.081 1.00 0.00 ATOM 644 C CYS 158 4.876-8.765-2.925 1.00 0.00 ATOM 645 O CYS 158 5.921-9.199-3.405 1.00 0.00 ATOM 646 N SER 159 4.030-9.525-2.232 1.00 0. 00 ATOM 647 H SER 159 3.216-9.118-1.866 1.00 0.00 ATOM 648 CA SER 159 4.280-10.945-1.984 1.00 0.00 ATOM 649 HA SER 159 5.267-11.027-1.551 1.00 0.00 ATOM 650 CB SER 159 3.265-11.496-0.985 1.00 0.00 ATOM 651 1HB SER 159 3.325-12.575-0.978 1.00 0.00 ATOM 652 2HB SER 159 2.272-11.192-1.283 1.00 0.00 ATOM 653 QB SER 159 2.798-11.884-1.131 1.00 0.00 ATOM 654 OG SER 159 3.525-11.009 0.327 1.00 0.00 ATOM 655 HG SER 159 4.443-10.710 0.375 1.00 0.00 ATOM 656 C SER 159 4.253-11.785-3.265 1.00 0.00 ATOM 657 O SER 159 4.823-12.873-3.290 1.00 0.00 ATOM 658 N GLU 160 3.605-11.284-4.321 1.00 0.00 ATOM 659 H GLU 160 3.168-10.407-4.249 1.00 0.00 ATOM 660 CA GLU 160 3.547-12.007-5.592 1.00 0.00 ATOM 661 HA GLU 160 3.185-13.006-5.399 1.00 0.00 ATOM 662 CB GLU 160 2.615-11.303-6.586 1.00 0. 00 ATOM 663 1HB GLU 160 3.193-10.590-7.159 1.00 0.00 ATOM 664 2HB GLU 160 1.852-10.773-6.036 1.00 0.00

ATOM 665 QB GLU 160 2.522-10.682-6.598 1.00 0. 00 ATOM 666 CG GLU 160 1.930-12.246-7.563 1.00 0.00 ATOM 667 1HG GLU 160 0.870-12.254-7.354 1.00 0.00 ATOM 668 2HG GLU 160 2.331-13.239-7.430 1.00 0.00 ATOM 669 QG GLU 160 1.600-12.747-7.392 1.00 0.00 ATOM 670 CD GLU 160 2.135-11.833-9.007 1.00 0.00 ATOM 671 OE1 GLU 160 2.871-10.852-9.247 1.00 0.00 ATOM 672 OE2 GLU 160 1.559-12.491-9.898 1.00 0.00 ATOM 673 C GLU 160 4.954-12.086-6.163 1.00 0.00 ATOM 674 O GLU 160 5.339-13.057-6.816 1.00 0.00 ATOM 675 N LYS+ 161 5.725-11.054-5.856 1.00 0.00 ATOM 676 H LYS+ 161 5.355-10.339-5.302 1.00 0.00 ATOM 677 CA LYS+ 161 7.105-10.971-6.267 1.00 0.00 ATOM 678 HA LYS+ 161 7.234-11.590-7.143 1.00 0.00 ATOM 679 CB LYS+ 161 7.484-9.521-6.594 1.00 0.00 ATOM 680 1HB LYS+ 161 7.854-9.050-5.696 1.00 0.00 ATOM 681 2HB LYS+ 161 6.598-8.999-6.921 1.00 0.00 ATOM 682 QB LYS+ 161 7.226-9.025-6.309 1.00 0.00 ATOM 683 CG LYS+ 161 8.548-9.394-7.678 1.00 0.00 ATOM 684 1HG LYS+ 161 8.071-9.088-8.599 1.00 0.00 ATOM 685 2HG LYS+ 161 9.019-10.356-7.819 1.00 0.00 ATOM 686 QG LYS+ 161 8.545-9.722-8.209 1.00 0.00 ATOM 687 CD LYS+ 161 9.613-8.372-7.307 1.00 0.00 ATOM 688 1HD LYS+ 161 9.639-8.265-6.233 1.00 0.00 ATOM 689 2HD LYS+ 161 9.357-7.424-7.759 1.00 0. 00 ATOM 690 QD LYS+ 161 9.498-7.845-6.996 1.00 0. 00 ATOM 691 CE LYS+ 161 10.991-8.797-7.801 1. 00 0.00 ATOM 692 1HE LYS+ 161 11.448-7.962-8.314 1.00 0. 00 ATOM 693 2HE LYS+ 161 10.872-9.619-8.493 1.00 0.00 ATOM 694 QE LYS+ 161 11.160-8.791-8.404 1.00 0.00 ATOM 695 NZ LYS+ 161 11.881-9.229-6.686 1.00 0.00 ATOM 696 1HZ LYS+ 161 11. 810-8. 569-5.887 1.00 0.00 ATOM 697 2HZ LYS+ 161 12.870-9.260-7.006 1.00 0.00 ATOM 698 3HZ LYS+ 161 11.609-10.189-6.354 1.00 0. 00 ATOM 699 QZ LYS+ 161 12.096-9.340-6.416 1.00 0.00 ATOM 700 C LYS+ 161 7.970-11.510-5.136 1.00 0.00 ATOM 701 O LYS+ 161 7.646-12.519-4.519 1.00 0.00 ATOM 702 N SER 162 9.065-10.837-4.853 1.00 0. 00 ATOM 703 H SER 162 9.280-10.036-5.361 1.00 0. 00 ATOM 704 CA SER 162 9.939-11.268-3.786 1.00 0.00 ATOM 705 HA SER 162 9.520-12.171-3.370 1.00 0.00 ATOM 706 CB SER 162 11.337-11.579-4.327 1.00 0.00 ATOM 707 1HB SER 162 11.674-12.523-3.920 1.00 0.00 ATOM 708 2HB SER 162 12.018-10.797-4.024 1.00 0.00 ATOM 709 QB SER 162 11.846-11.660-3.972 1.00 0. 00 ATOM 710 OG SER 162 11.328-11.666-5.749 1.00 0.00 ATOM 711 HG SER 162 11.176-12.585-6.007 1.00 0.00 ATOM 712 C SER 162 10.022-10.220-2.683 1.00 0.00 ATOM 713 O SER 162 11. 111-9. 850-2.265 1.00 0.00 ATOM 714 N THR 163 8.876-9.733-2.207 1.00 0. 00 ATOM 715 H THR 163 8.017-10.047-2.571 1.00 0.00 ATOM 716 CA THR 163 8.882-8.741-1.137 1.00 0.00 ATOM 717 HA THR 163 9.813-8.859-0.598 1.00 0.00 ATOM 718 CB THR 163 8.814-7.308-1.677 1.00 0.00 ATOM 719 HB THR 163 8.779-6.635-0.828 1.00 0.00 ATOM 720 QG2 THR 163 10.281-6.816-2.733 1.00 0. 00 ATOM 721 OG1 THR 163 7.654-7.103-2.457 1.00 0.00 ATOM 722 1HG THR 163 7.486-6.161-2.544 1.00 0.00 ATOM 723 CG2 THR 163 9.998-6.909-2. 530 1.00 0.00 ATOM 724 1HG2 THR 163 9.664-6.691-3.533 1.00 0.00 ATOM 725 2HG2 THR 163 10.710-7.723-2. 557 1.00 0.00 ATOM 726 3HG2 THR 163 10.469-6.034-2.108 1.00 0.00 ATOM 727 C THR 163 7.735-8.979-0.157 1.00 0.00 ATOM 728 O THR 163 6.736-9.622-0.478 1.00 0.00 ATOM 729 N ASN 164 7.895-8.456 1.047 1.00 0.00 ATOM 730 H ASN 164 8.723-7.959 1.242 1.00 0.00 ATOM 731 CA ASN 164 6.889-8.604 2.099 1.00 0.00 ATOM 732 HA ASN 164 6.018-9.082 1.665 1.00 0.00 ATOM 733 CB ASN 164 7.437-9.473 3.237 1.00 0. 00 ATOM 734 1HB ASN 164 7.163-10.502 3.062 1.00 0.00 ATOM 735 2HB ASN 164 7.014-9.143 4.174 1.00 0.00 ATOM 736 QB ASN 164 7.088-9.823 3.618 1.00 0.00

ATOM 737 CG ASN 164 8.948-9.389 3.334 1.00 0.00 ATOM 738 OD1 ASN 164 9.631-10.401 3.432 1.00 0.00 ATOM 739 ND2 ASN 164 9.472-8.170 3.312 1.00 0.00 ATOM 740 1HD2 ASN 164 8.859-7.406 3.257 1.00 0.00 ATOM 741 2HD2 ASN 164 10.444-8.085 3.294 1.00 0.00 ATOM 742 QD2 ASN 164 9.651-7.746 3.275 1.00 0.00 ATOM 743 C ASN 164 6.493-7.241 2.652 1.00 0.00 ATOM 744 O ASN 164 7.356-6.412 2.939 1.00 0.00 ATOM 745 N LEU 165 5. 194-7.008 2.793 1.00 0.00 ATOM 746 H LEU 165 4.556-7.706 2.545 1.00 0.00 ATOM 747 CA LEU 165 4.693-5.734 3.307 1.00 0.00 ATOM 748 HA LEU 165 5.188-4.935 2.. 775 1.00 0.00 ATOM 749 CB LEU 165 3.186-5.617 3.087 1.00 0.00 ATOM 750 1HB LEU 165 2.714-5.450 4.042 1.00 0.00 ATOM 751 2HB LEU 165 2.823-6.549 2.680 1.00 0.00 ATOM 752 QB LEU 165 2.768-6.000 3.361 1.00 0.00 ATOM 753 CG LEU 165 2.758-4.495 2.163 1.00 0.00 ATOM 754 HG LEU 165 3.291-3.593 2.426 1.00 0.00 ATOM 755 QD1 LEU 165 3.175-4.928 0.392 1.00 0.00 ATOM 756 QD2 LEU 165 0.919-4.168 2.358 1.00 0.00 ATOM 757 CD1 LEU 165 3.096-4.845 0.733 1.00 0.00 ATOM 758 1HD1 LEU 165 2.206-4.765 0.124 1.00 0.00 ATOM 759 2HD1 LEU 165 3.473-5.855 0.689 1.00 0.00 ATOM 760 3HD1 LEU 165 3.846-4.162 0.363 1.00 0.00 ATOM 761 CD2 LEU 165 1.272-4.231 2.322 1.00 0.00 ATOM 762 1HD2 LEU 165 0.713-5.064 1.921 1.00 0.00 ATOM 763 2HD2 LEU 165 1.008-3.331 1.786 1.00 0.00 ATOM 764 3HD2 LEU 165 1.037-4.109 3.368 1.00 0.00 ATOM 765 QQD LEU 165 2.047-4.548 1.375 1.00 0.00 ATOM 766 C LEU 165 4.984-5.577 4.786 1.00 0.00 ATOM 767 O LEU 165 4.626-6.431 5.594 1.00 0.00 ATOM 768 N HIS+ 166 5.618-4.471 5.124 1.00 0.00 ATOM 769 H HIS+ 166 5.866-3.827 4.425 1.00 0.00 ATOM 770 CA HIS+ 166 5.948-4.169 6.502 1.00 0.00 ATOM 771 HA HIS+ 166 5.650-5.012 7.108 1.00 0.00 ATOM 772 CB HIS+ 166 7.460-3.955 6.642 1.00 0. 00 ATOM 773 1HB HIS+ 166 7.761-3.148 5.987 1.00 0.00 ATOM 774 2HB HIS+ 166 7.973-4.857 6.350 1.00 0.00 ATOM 775 QB HIS+ 166 7.867-4.003 6. 168 1.00 0.00 ATOM 776 CG HIS+ 166 7.903-3.606 8.028 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.843-4.482 9.090 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.406-2.455 8.520 1.00 0.00 ATOM 779 1HD HIS+ 166 7.513-5.405 9.054 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.291-3.878 10.178 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.641-2.643 9.857 1.00 0. 00 ATOM 782 2HD HIS+ 166 8.573-1.540 7.960 1.00 0.00 ATOM 783 1HE HIS+ 166 8.361-4.318 11.162 1.00 0.00 ATOM 784 2HE HIS+ 166 8.788-1.919 10.502 1.00 0.00 ATOM 785 C HIS+ 166 5.176-2.931 6.963 1.00 0.00 ATOM 786 O HIS+ 166 4.543-2.943 8.019 1.00 0.00 ATOM 787 N ASP 167 5.231-1.865 6.162 1.00 0.00 ATOM 788 H ASP 167 5.751-1.917 5.331 1.00 0.00 ATOM 789 CA ASP 167 4.538-0.618 6.500 1.00 0.00 ATOM 790 HA ASP 167 4.045-0.768 7.449 1.00 0.00 ATOM 791 CB ASP 167 5.528 0.550 6.642 1.00 0.00 ATOM 792 1HB ASP 167 5.137 1.252 7.364 1.00 0.00 ATOM 793 2HB ASP 167 5.623 1.045 5.688 1.00 0.00 ATOM 794 QB ASP 167 5.380 1.148 6.526 1.00 0.00 ATOM 795 CG ASP 167 6.911 0.126 7.092 1.00 0.00 ATOM 796 OD1 ASP 167 7.685-0.382 6.250 1.00 0.00 ATOM 797 OD2 ASP 167 7.228 0.312 8.285 1.00 0.00 ATOM 798 C ASP 167 3.488-0.248 5.455 1.00 0.00 ATOM 799 O ASP 167 3.784 0.432 4.477 1.00 0.00 ATOM 800 N TYR 168 2.259-0.689 5.671 1.00 0.00 ATOM 801 H TYR 168 2.080-1.218 6.476 1.00 0.00 ATOM 802 CA TYR 168 1.153-0.388 4.759 1.00 0.00 ATOM 803 HA TYR 168 1.566-0.197 3.770 1.00 0.00 ATOM 804 CB TYR 168 0.184-1.570 4.681 1.00 0.00 ATOM 805 1HB TYR 168 0.623-2.346 4.076 1.00 0.00 ATOM 806 2HB TYR 168-0.736-1.240 4.221 1.00 0.00 ATOM 807 QB TYR 168-0.057-1.793 4.148 1.00 0.00 ATOM 808 QD TYR 168-0.200-2.232 6. 190 1.00 0.00

ATOM 809 QE TYR 168-0.755-3.173 8.391 1.00 0.00 ATOM 810 QR TYR 168-0. 478-2.702 7.290 1.00 0.00 ATOM 811 CG TYR 168-0.161-2.163 6.033 1.00 0.00 ATOM 812 CD1 TYR 168 0.677-3.087 6.648 1.00 0.00 ATOM 813 1HD TYR 168 1.585-3.390 6.145 1.00 0.00 ATOM 814 CE1 TYR 168 0.369-3.617 7.884 1.00 0.00 ATOM 815 1HE TYR 168 1.034-4.333 8.345 1.00 0.00 ATOM 816 CZ TYR 168-0.789-3.229 8.523 1.00 0.00 ATOM 817 CE2 TYR 168-1. 637-2.316 7.935 1.00 0.00 ATOM 818 2HE TYR 168-2. 544-2.012 8.437 1.00 0.00 ATOM 819 CD2 TYR 168-1.322-1.788 6.698 1.00 0.00 ATOM 820 2HD TYR 168-1.985-1.073 6.235 1.00 0.00 ATOM 821 OH TYR 168-1.102-3.757 9.752 1.00 0. 00 ATOM 822 HH TYR 168-0.512-3.393 10.418 1.00 0.00 ATOM 823 C TYR 168 0.402 0.857 5.215 1.00 0.00 ATOM 824 O TYR 168 0.358 1.171 6.404 1.00 0.00 ATOM 825 N GLY 169-0.202 1.542 4.264 1.00 0.00 ATOM 826 H GLY 169-0.140 1.230 3.335 1.00 0.00 ATOM 827 CA GLY 169-0.961 2.733 4.564 1.00 0.00 ATOM 828 1HA GLY 169-0.316 3.596 4.475 1.00 0.00 ATOM 829 2HA GLY 169-1.335 2.671 5.575 1.00 0.00 ATOM 830 QA GLY 169-0.826 3.133 5.025 1.00 0.00 ATOM 831 C GLY 169-2. 114 2.879 3.609 1.00 0.00 ATOM 832 O GLY 169-2.087 2.311 2.518 1.00 0.00 ATOM 833 N MET 170-3.131 3.619 4.004 1.00 0.00 ATOM 834 H MET 170-3.103 4.046 4.886 1.00 0.00 ATOM 835 CA MET 170-4.294 3.814 3.156 1.00 0.00 ATOM 836 HA MET 170-4.002 3.586 2.133 1.00 0.00 ATOM 837 CB MET 170-5.427 2.876 3.581 1.00 0.00 ATOM 838 1HB MET 170-6.356 3.247 3.173 1.00 0.00 ATOM 839 2HB MET 170-5.494 2.876 4.659 1.00 0.00 ATOM 840 QB MET 170-5.925 3.061 3.916 1.00 0.00 ATOM 841 CG MET 170-5.239 1.441 3.113 1.00 0.00 ATOM 842 1HG MET 170-4.691 1.451 2.181 1.00 0.00 ATOM 843 2HG MET 170-6.212 1.000 2.951 1.00 0.00 ATOM 844 QG MET 170-5.452 1.225 2.566 1.00 0.00 ATOM 845 SD MET 170-4.340 0.427 4.303 1.00 0.00 ATOM 846 QE MET 170-3.108-0.766 3.008 1.00 0.00 ATOM 847 CE MET 170-3. 314-0.567 3.225 1.00 0.00 ATOM 848 1HE MET 170-3.941-1.147 2.565 1.00 0.00 ATOM 849 2HE MET 170-2.705-1.231 3.820 1.00 0.00 ATOM 850 3HE MET 170-2.676 0.080 2.639 1.00 0.00 ATOM 851 C MET 170-4.749 5.261 3.227 1.00 0.00 ATOM 852 O MET 170-5.200 5.732 4.271 1.00 0. 00 ATOM 853 N LEU 171-4.612 5.964 2.118 1.00 0.00 ATOM 854 H LEU 171-4.236 5.530 1.323 1.00 0.00 ATOM 855 CA LEU 171-4.991 7.366 2.051 1.00 0.00 ATOM 856 HA LEU 171-5. 194 7.698 3. 059 1.00 0. 00 ATOM 857 CB LEU 171-3.835 8.196 1.480 1.00 0.00 ATOM 858 1HB LEU 171-3.000 8.127 2.162 1.00 0.00 ATOM 859 2HB LEU 171-4.151 9.228 1.431 1.00 0.00 ATOM 860 QB LEU 171-3. 576 8.677 1.796 1.00 0.00 ATOM 861 CG LEU 171-3.350 7.777 0.089 1.00 0.00 ATOM 862 HG LEU 171-4.159 7.299-0.443 1.00 0.00 ATOM 863 QD1 LEU 171-2.810 9.273-0.897 1.00 0.00 ATOM 864 QD2 LEU 171-1. 927 6.556 0.212 1.00 0.00 ATOM 865 CD1 LEU 171-2.915 8.987-0.706 1.00 0.00 ATOM 866 1HD1 LEU 171-2.715 9.807-0.036 1.00 0.00 ATOM 867 2HD1 LEU 171-3.696 9.267-1.398 1.00 0.00 ATOM 868 3HD1 LEU 171-2.017 8.746-1.257 1.00 0.00 ATOM 869 CD2 LEU 171-2.201 6.790 0.189 1.00 0.00 ATOM 870 1HD2 LEU 171-2.577 5.784 0.081 1.00 0.00 ATOM 871 2HD2 LEU 171-1.719 6.894 1.151 1.00 0.00 ATOM 872 3HD2 LEU 171-1.485 6.992-0.594 1.00 0.00 ATOM 873 QQD LEU 171-2.369 7.915-0.342 1.00 0.00 ATOM 874 C LEU 171-6.248 7.553 1.211 1.00 0.00 ATOM 875 0 LEU 171-6.948 6.582 0.917 1.00 0.00 ATOM 876 N LEU 172-6.517 8.807 0.831 1.00 0.00 ATOM 877 H LEU 172-5.904 9.520 1.105 1.00 0.00 ATOM 878 CA LEU 172-7.687 9.161 0.018 1.00 0.00 ATOM 879 HA LEU 172-7.821 10.230 0.085 1.00 0.00 ATOM 880 CB LEU 172-7.450 8.785-1.448 1.00 0.00

ATOM 881 1HB LEU 172-8. 355 8.338-1.830 1.00 0.00 ATOM 882 2HB LEU 172-6.664 8.045-1.484 1.00 0.00 ATOM 883 QB LEU 172-7. 510 8.191-1.657 1.00 0.00 ATOM 884 CG LEU 172-7.062 9.943-2.371 1.00 0.00 ATOM 885 HG LEU 172-6. 021 10.192-2.210 1.00 0.00 ATOM 886 QD1 LEU 172-7. 260 9.444-4.171 1.00 0.00 ATOM 887 QD2 LEU 172-8.090 11.474-2.005 1.00 0.00 ATOM 888 CD1 LEU 172-7.223 9.538-3.825 1.00 0.00 ATOM 889 1HD1 LEU 172-7.363 8.470-3.891 1.00 0.00 ATOM 890 2HD1 LEU 172-6.335 9.820-4.374 1.00 0.00 ATOM 891 3HD1 LEU 172-8.080 10.042-4.247 1.00 0.00 ATOM 892 CD2 LEU 172-7.895 11.180-2.073 1.00 0.00 ATOM 893 1HD2 LEU 172-7.241 11.990-1. 784 1.00 0.00 ATOM 894 2HD2 LEU 172-8.583 10.969-1.271 1.00 0.00 ATOM 895 3HD2 LEU 172-8.446 11.463-2.958 1.00 0. 00 ATOM 896 QQD LEU 172-7.675 10.459-3.088 1.00 0.00 ATOM 897 C LEU 172-8.955 8.476 0. 523 1.00 0.00 ATOM 898 O LEU 172-9.498 7.607-0.154 1.00 0.00 ATOM 899 N PRO 173-9.446 8.850 1.718 1.00 0.00 ATOM 900 CD PRO 173-8.871 9.878 2.606 1.00 0.00 ATOM 901 CA PRO 173-10.653 8.243 2.291 1.00 0.00 ATOM 902 HA PRO 173-10.477 7.210 2.559 1.00 0.00 ATOM 903 CB PRO 173-10.909 9.067 3.554 1.00 0.00 ATOM 904 1HB PRO 173-11.283 8.423 4.337 1.00 0.00 ATOM 905 2HB PRO 173-11.634 9.840 3.341 1.00 0.00 ATOM 906 QB PRO 173-11.459 9.131 3.839 1.00 0.00 ATOM 907 CG PRO 173-9.582 9.643 3.911 1.00 0.00 ATOM 908 1HG PRO 173-9.028 8.942 4.518 1.00 0. 00 ATOM 909 2HG PRO 173-9.716 10.575 4.440 1.00 0.00 ATOM 910 QG PRO 173-9.372 9.758 4.479 1.00 0.00 ATOM 911 1HD PRO 173-7.807 9.733 2.724 1.00 0.00 ATOM 912 2HD PRO 173-9.081 10.871 2.236 1.00 0.00 ATOM 913 QD PRO 173-8.444 10.302 2.480 1.00 0.00 ATOM 914 C PRO 173-11.851 8.319 1.349 1.00 0.00 ATOM 915 O PRO 173-12.082 9.336 0.690 1.00 0.00 ATOM 916 N CYS 174-12.605 7.234 1.292 1.00 0.00 ATOM 917 H CYS 174-12.363 6.458 1.846 1.00 0.00 ATOM 918 CA CYS 174-13.780 7.156 0.440 1.00 0.00 ATOM 919 HA CYS 174-13.820 8.056-0.156 1.00 0.00 ATOM 920 CB CYS 174-13.687 5.944-0.485 1.00 0.00 ATOM 921 1HB CYS 174-13.975 5.061 0.065 1.00 0.00 ATOM 922 2HB CYS 174-12.667 5.836-0.823 1.00 0.00 ATOM 923 QB CYS 174-13. 321 5.448-0.379 1.00 0.00 ATOM 924 SG CYS 174-14.750 6.052-1.961 1.00 0.00 ATOM 925 C CYS 174-15.041 7.070 1.287 1.00 0.00 ATOM 926 O CYS 174-16.111 7.513 0.878 1.00 0.00 ATOM 927 N GLY 175-14.900 6.503 2.475 1.00 0.00 ATOM 928 H GLY 175-14. 015 6.175 2.750 1. 00 0.00 ATOM 929 CA GLY 175-16.022 6.371 3.380 1.00 0. 00 ATOM 930 1HA GLY 175-16.560 5.465 3.148 1.00 0.00 ATOM 931 2HA GLY 175-16.681 7.217 3.253 1.00 0.00 ATOM 932 QA GLY 175-16.621 6.341 3. 200 1. 00 0.00 ATOM 933 C GLY 175-15.559 6.316 4.813 1.00 0.00 ATOM 934 O GLY 175-14.427 6.692 5.105 1.00 0.00 ATOM 935 N ILE 176-16.422 5.836 5.703 1.00 0.00 ATOM 936 H ILE 176-17.306 5.544 5.403 1.00 0.00 ATOM 937 CA ILE 176-16.076 5.720 7.115 1.00 0.00 ATOM 938 HA ILE 176-15.826 6.705 7.485 1.00 0.00 ATOM 939 CB ILE 176-17. 256 5.164 7.940 1.00 0.00 ATOM 940 HB ILE 176-17.272 4.092 7.818 1.00 0.00 ATOM 941 QG2 ILE 176-17.019 5.538 9.769 1.00 0.00 ATOM 942 CG2 ILE 176-17. 064 5.467 9.420 1.00 0.00 ATOM 943 1HG2 ILE 176-16.037 5.749 9.600 1.00 0.00 ATOM 944 2HG2 ILE 176-17.303 4.589 10.001 1.00 0.00 ATOM 945 3HG2 ILE 176-17.716 6.278 9.708 1.00 0.00 ATOM 946 CG1 ILE 176-18. 584 5.744 7.443 1.00 0.00 ATOM 947 1HG1 ILE 176-18.745 5.433 6.421 1.00 0.00 ATOM 948 2HG1 ILE 176-18.537 6.822 7.483 1.00 0.00 ATOM 949 QG1 ILE 176-18.641 6.127 6.952 1.00 0.00 ATOM 950 QD1 ILE 176-20.066 5.197 8.452 1.00 0.00 ATOM 951 CD1 ILE 176-19.781 5.302 8.257 1.00 0.00 ATOM 952 1HD1 ILE 176-20.419 6.152 8.449 1.00 0.00

ATOM 953 2HD1 ILE 176-19. 443 4.888 9.196 1.00 0. 00 ATOM 954 3HD1 ILE 176-20.334 4.553 7.711 1.00 0.00 ATOM 955 C ILE 176-14.867 4.802 7.281 1.00 0.00 ATOM 956 O ILE 176-13.868 5.177 7.892 1.00 0.00 ATOM 957 N ASP 177-14.965 3.606 6.707 1.00 0.00 ATOM 958 H ASP 177-15.782 3.379 6.221 1.00 0. 00 ATOM 959 CA ASP 177-13.880 2.633 6.760 1.00 0.00 ATOM 960 HA ASP 177-13.026 3.116 7. 215 1.00 0. 00 ATOM 961 CB ASP 177-14.273 1.418 7.606 1.00 0.00 ATOM 962 1HB ASP 177-14.905 0.767 7.021 1.00 0.00 ATOM 963 2HB ASP 177-14. 813 1.752 8.478 1.00 0.00 ATOM 964 QB ASP 177-14. 859 1.259 7.749 1.00 0.00 ATOM 965 CG ASP 177-13. 065 0.623 8.070 1.00 0.00 ATOM 966 OD1 ASP 177-11. 924 1.084 7.849 1.00 0.00 ATOM 967 OD2 ASP 177-13.260-0.466 8.645 1.00 0.00 ATOM 968 C ASP 177-13. 499 2.192 5.346 1.00 0.00 ATOM 969 O ASP 177-13.249 1.014 5.081 1.00 0.00 ATOM 970 N LYS+ 178-13.452 3.151 4.432 1.00 0.00 ATOM 971 H LYS+ 178-13. 652 4.073 4.698 1.00 0.00 ATOM 972 CA LYS+ 178-13.087 2.870 3.049 1.00 0.00 ATOM 973 HA LYS+ 178-12.587 1.911 3.028 1.00 0.00 ATOM 974 CB LYS+ 178-14.313 2.820 2.133 1.00 0.00 ATOM 975 1HB LYS+ 178-13.984 2.571 1.133 1.00 0.00 ATOM 976 2HB LYS+ 178-14.770 3.796 2.117 1.00 0.00 ATOM 977 QB LYS+ 178-14. 377 3.183 1.625 1.00 0.00 ATOM 978 CG LYS+ 178-15.361 1.799 2.563 1.00 0.00 ATOM 979 1HG LYS+ 178-16.198 2.322 3.003 1.00 0.00 ATOM 980 2HG LYS+ 178-14.924 1.137 3.297 1.00 0.00 ATOM 981 QG LYS+ 178-15.561 1.729 3.150 1.00 0.00 ATOM 982 CD LYS+ 178-15.859 0.970 1.385 1.00 0.00 ATOM 983 1HD LYS+ 178-15. 295 1.242 0.504 1.00 0.00 ATOM 984 2HD LYS+ 178-16.906 1.187 1.225 1.00 0. 00 ATOM 985 QD LYS+ 178-16.101 1.214 0.864 1.00 0.00 ATOM 986 CE LYS+ 178-15.700-0.528 1.633 1.00 0.00 ATOM 987 1HE LYS+ 178-16.529-0.870 2.238 1.00 0.00 ATOM 988 2HE LYS+ 178-14.775-0.697 2.165 1.00 0.00 ATOM 989 QE LYS+ 178-15.652-0.784 2.201 1.00 0.00 ATOM 990 NZ LYS+ 178-15.676-1.304 0.360 1.00 0.00 ATOM 991 1HZ LYS+ 178-15.295-0.720-0.419 1.00 0.00 ATOM 992 2HZ LYS+ 178-16.630-1.617 0.104 1.00 0.00 ATOM 993 3HZ LYS+ 178-15.065-2.154 0.459 1.00 0.00 ATOM 994 QZ LYS+ 178-15.664-1.497 0.048 1.00 0.00 ATOM 995 C LYS+ 178-12.114 3.917 2.558 1.00 0.00 ATOM 996 O LYS+ 178-12.233 5.093 2.893 1.00 0.00 ATOM 997 N PHE 179-11.146 3.482 1.776 1.00 0.00 ATOM 998 H PHE 179-11.105 2.529 1.549 1.00 0.00 ATOM 999 CA PHE 179-10.132 4.375 1.258 1.00 0.00 ATOM 1000 HA PHE 179-10.438 5.389 1.461 1.00 0.00 ATOM 1001 CB PHE 179-8.797 4.106 1.950 1.00 0. 00 ATOM 1002 1HB PHE 179-8.094 4.847 1.633 1.00 0.00 ATOM 1003 2HB PHE 179-8.432 3.136 1.652 1.00 0.00 ATOM 1004 QB PHE 179-8.263 3.991 1.642 1.00 0.00 ATOM 1005 QD PHE 179-8.875 4.141 3.620 1.00 0.00 ATOM 1006 QE PHE 179-9. 004 4.203 6.075 1.00 0.00 ATOM 1007 QR PHE 179-8.966 4.185 5.340 1.00 0.00 ATOM 1008 CG PHE 179-8.867 4.139 3.453 1.00 0.00 ATOM 1009 CD1 PHE 179-9.203 3.001 4.173 1.00 0.00 ATOM 1010 1HD PHE 179-9.410 2.081 3.646 1.00 0.00 ATOM 1011 CE1 PHE 179-9.276 3.033 5.552 1.00 0.00 ATOM 1012 1HE PHE 179-9.542 2.141 6.101 1.00 0.00 ATOM 1013 CZ PHE 179-9.011 4.207 6.228 1.00 0.00 ATOM 1014 HZ PHE 179-9.070 4.236 7.307 1.00 0.00 ATOM 1015 CE2 PHE 179-8.674 5.346 5.523 1.00 0.00 ATOM 1016 2HE PHE 179-8.466 6.266 6. 050 1.00 0.00 ATOM 1017 CD2 PHE 179-8. 604 5.309 4.144 1.00 0.00 ATOM 1018 2HD PHE 179-8.340 6.201 3.595 1.00 0.00 ATOM 1019 C PHE 179-9.961 4.192-0.235 1.00 0.00 ATOM 1020 O PHE 179-10.633 3.366-0.849 1.00 0.00 ATOM 1021 N ARG+ 180-9.039 4.953-0.800 1.00 0.00 ATOM 1022 H ARG+ 180-8.533 5.581-0.237 1.00 0.00 ATOM 1023 CA ARG+ 180-8.736 4.876-2.222 1.00 0.00 ATOM 1024 HA ARG+ 180-9.166 3.962-2.609 1.00 0. 00

ATOM 1025 CB ARG+ 180-9.326 6.067-2.985 1.00 0.00 ATOM 1026 1HB ARG+ 180-9.153 5.913-4.042 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.816 6. 965-2.679 1.00 0.00 ATOM 1028 QB ARG+ 180-8.985 6.439-3.361 1.00 0.00 ATOM 1029 CG ARG+ 180-10. 816 6.266-2.774 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.977 6.702-1.799 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.306 5.303-2.827 1.00 0.00 ATOM 1032 QG ARG+ 180-11. 142 6.002-2.313 1.00 0.00 ATOM 1033 CD ARG+ 180-11.411 7.181-3.834 1.00 0.00 ATOM 1034 1HD ARG+ 180-11.799 6. 569-4. 639 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.631 7.822-4.220 1.00 0.00 ATOM 1036 QD ARG+ 180-11.215 7.195-4.430 1.00 0.00 ATOM 1037 NE ARG+ 180-12.492 8.012-3.307 1.00 0.00 ATOM 1038 HE ARG+ 180-13.414 7.746-3.529 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.299 9.096-2.554 1.00 0.00 ATOM 1040 NH1 ARG+ 180-11.066 9.479-2.246 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-10.281 8.954-2.579 1.00 0. 00 ATOM 1042 2HH1 ARG+ 180-10.917 10.287-1.676 1.00 0.00 ATOM 1043 QH1 ARG+ 180-10.599 9.620-2.128 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.339 9.794-2. 113 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-14.271 9.511-2.346 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.196 10.602-1. 537 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13.734 10.056-1.942 1.00 0.00 ATOM 1048 C ARG+ 180-7.227 4.841-2.440 1.00 0.00 ATOM 1049 O ARG+ 180-6.757 4.481-3.506 1.00 0.00 ATOM 1050 N GLY 181-6.465 5.229-1.430 1.00 0.00 ATOM 1051 H GLY 181-6.879 5.515-0.587 1.00 0.00 ATOM 1052 CA GLY 181-5.024 5. 241-1.574 1.00 0.00 ATOM 1053 1HA GLY 181-4.650 6.202-1.251 1.00 0.00 ATOM 1054 2HA GLY 181-4.781 5.107-2.618 1.00 0.00 ATOM 1055 QA GLY 181-4. 716 5.654-1.935 1.00 0.00 ATOM 1056 C GLY 181-4.338 4.157-0.776 1.00 0.00 ATOM 1057 O GLY 181-4. 880 3.670 0.214 1.00 0.00 ATOM 1058 N VAL 182-3.136 3.787-1.209 1.00 0.00 ATOM 1059 H VAL 182-2.764 4.224-1.998 1.00 0.00 ATOM 1060 CA VAL 182-2.350 2.756-0.539 1.00 0.00 ATOM 1061 HA VAL 182-2.685 2.691 0.486 1.00 0. 00 ATOM 1062 CB VAL 182-2. 515 1.363-1.202 1.00 0.00 ATOM 1063 HB VAL 182-1.719 1.242-1.924 1.00 0.00 ATOM 1064 QG1 VAL 182-2.346-0.003 0.077 1.00 0.00 ATOM 1065 QG2 VAL 182-4.159 1.204-2.108 1.00 0.00 ATOM 1066 CG1 VAL 182-2.378 0.260-0.167 1.00 0.00 ATOM 1067 1HG1 VAL 182-2.363 0.693 0.822 1.00 0.00 ATOM 1068 2HG1 VAL 182-1.459-0.282-0.338 1.00 0.00 ATOM 1069 3HG1 VAL 182-3.215-0.418-0.251 1.00 0.00 ATOM 1070 CG2 VAL 182-3.844 1.235-1.935 1.00 0.00 ATOM 1071 1HG2 VAL 182-4.076 0.190-2.080 1.00 0.00 ATOM 1072 2HG2 VAL 182-3.775 1.725-2.894 1.00 0. 00 ATOM 1073 3HG2 VAL 182-4.625 1.698-1.349 1.00 0.00 ATOM 1074 QQG VAL 182-3.253 0.601-1.015 1.00 0.00 ATOM 1075 C VAL 182-0.864 3.119-0.542 1. 00 0. 00 ATOM 1076 O VAL 182-0.292 3.419-1.589 1.00 0.00 ATOM 1077 N GLU 183-0.255 3.081 0.637 1.00 0.00 ATOM 1078 H GLU 183-0.778 2.833 1.429 1.00 0.00 ATOM 1079 CA GLU 183 1.162 3.390 0.806 1.00 0.00 ATOM 1080 HA GLU 183 1.610 3.483-0.173 1.00 0. 00 ATOM 1081 CB GLU 183 1.331 4.705 1.575 1.00 0.00 ATOM 1082 1HB GLU 183 1.695 5.461 0.894 1.00 0.00 ATOM 1083 2HB GLU 183 2.064 4.557 2.355 1.00 0.00 ATOM 1084 QB GLU 183 1.879 5.009 1.624 1.00 0.00 ATOM 1085 CG GLU 183 0.055 5.224 2.223 1.00 0.00 ATOM 1086 1HG GLU 183-0.352 4.452 2.859 1.00 0.00 ATOM 1087 2HG GLU 183-0.657 5.464 1.448 1.00 0.00 ATOM 1088 QG GLU 183-0.505 4.958 2.153 1.00 0.00 ATOM 1089 CD GLU 183 0.293 6.463 3.059 1.00 0.00 ATOM 1090 OE1 GLU 183-0.321 7.510 2.761 1.00 0.00 ATOM 1091 OE2 GLU 183 1.104 6.394 3.999 1.00 0.00 ATOM 1092 C GLU 183 1.846 2.262 1.574 1.00 0.00 ATOM 1093 O GLU 183 1.878 2.273 2.796 1.00 0.00 ATOM 1094 N PHE 184 2.361 1.271 0.868 1.00 0.00 ATOM 1095 H PHE 184 2.294 1.286-0.103 1.00 0.00 ATOM 1096 CA PHE 184 2.991 0.132 1.527 1.00 0.00

ATOM 1097 HA PHE 184 2.879 0.279 2.589 1.00 0.00 ATOM 1098 CB PHE 184 2.291-1.175 1.143 1.00 0.00 ATOM 1099 1HB PHE 184 1.395-1.287 1.736 1.00 0.00 ATOM 1100 2HB PHE 184 2.956-1.997 1.369 1.00 0.00 ATOM 1101 QB PHE 184 2.175-1.642 1.552 1.00 0.00 ATOM 1102 QD PHE 184 1.863-1.308-0.483 1.00 0.00 ATOM 1103 QE PHE 184 1.213-1.573-2.838 1.00 0. 00 ATOM 1104 QR PHE 184 1.406-1.496-2.131 1.00 0.00 ATOM 1105 CG PHE 184 1.909-1.294-0.316 1.00 0.00 ATOM 1106 CD1 PHE 184 0.940-0.474-0.882 1.00 0.00 ATOM 1107 1HD PHE 184 0.471 0.287-0.276 1.00 0.00 ATOM 1108 CE1 PHE 184 0.572-0.623-2.206 1.00 0.00 ATOM 1109 1HE PHE 184-0. 182 0.022-2.633 1.00 0.00 ATOM 1110 CZ PHE 184 1.173-1.592-2.984 1.00 0. 00 ATOM 1111 HZ PHE 184 0.882-1.718-4.015 1.00 0.00 ATOM 1112 CE2 PHE 184 2.138-2.408-2.437 1.00 0.00 ATOM 1113 2HE PHE 184 2.608-3.168-3.042 1.00 0.00 ATOM 1114 CD2 PHE 184 2.498-2.260-1.113 1.00 0.00 ATOM 1115 2HD PHE 184 3.255-2.903-0.690 1.00 0.00 ATOM 1116 C PHE 184 4.472-0.001 1.217 1.00 0.00 ATOM 1117 O PHE 184 4.907 0.199 0.089 1.00 0.00 ATOM 1118 N VAL 185 5.234-0.377 2.232 1.00 0.00 ATOM 1119 H VAL 185 4.817-0.540 3.105 1.00 0.00 ATOM 1120 CA VAL 185 6.663-0.581 2.090 1.00 0.00 ATOM 1121 HA VAL 185 6.955-0.272 1.095 1.00 0.00 ATOM 1122 CB VAL 185 7.464 0.248 3.123 1.00 0.00 ATOM 1123 HB VAL 185 7.642-0.371 3.995 1.00 0.00 ATOM 1124 QG1 VAL 185 9.122 0.763 2.419 1.00 0.00 ATOM 1125 QG2 VAL 185 6.502 1.767 3.674 1.00 0.00 ATOM 1126 CG1 VAL 185 8.805 0.663 2.553 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.576 0.484 3.287 1.00 0.00 ATOM 1128 2HG1 VAL 185 8.779 1.715 2.308 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.012 0.090 1.662 1.00 0.00 ATOM 1130 CG2 VAL 185 6.687 1.476 3.567 1.00 0.00 ATOM 1131 1HG2 VAL 185 7.045 1.796 4.535 1.00 0.00 ATOM 1132 2HG2 VAL 185 5.636 1.233 3.636 1.00 0.00 ATOM 1133 3HG2 VAL 185 6.826 2.273 2.851 1.00 0.00 ATOM 1134 QQG VAL 185 7.812 1.265 3.046 1.00 0.00 ATOM 1135 C VAL 185 6.984-2.063 2.263 1.00 0.00 ATOM 1136 O VAL 185 6.808-2.627 3.341 1.00 0.00 ATOM 1137 N CYS 186 7.434-2.703 1.193 1.00 0.00 ATOM 1138 H CYS 186 7.543-2.210 0.348 1.00 0.00 ATOM 1139 CA CYS 186 7.759-4.122 1.244 1.00 0.00 ATOM 1140 HA CYS 186 7.571-4.463 2.253 1.00 0.00 ATOM 1141 CB CYS 186 6.866-4.918 0.283 1.00 0.00 ATOM 1142 1HB CYS 186 5.849-4.884 0.646 1.00 0.00 ATOM 1143 2HB CYS 186 7.199-5.945 0.270 1.00 0.00 ATOM 1144 QB CYS 186 6.524-5.415 0.458 1.00 0.00 ATOM 1145 SG CYS 186 6.859-4.327-1.440 1.00 0.00 ATOM 1146 C CYS 186 9.231-4.348 0.927 1.00 0.00 ATOM 1147 O CYS 186 9.747-3.828-0.055 1.00 0.00 ATOM 1148 N CYS 187 9.912-5.115 1.766 1.00 0.00 ATOM 1149 H CYS 187 9.453-5.504 2.544 1.00 0.00 ATOM 1150 CA CYS 187 11.336-5.377 1.562 1.00 0.00 ATOM 1151 HA CYS 187 11.741-4.545 1.010 1.00 0.00 ATOM 1152 CB CYS 187 12.070-5.483 2.901 1.00 0.00 ATOM 1153 1HB CYS 187 12.872-6.201 2.805 1.00 0.00 ATOM 1154 2HB CYS 187 11.379-5.827 3.655 1.00 0.00 ATOM 1155 QB CYS 187 12.125-6.014 3.230 1.00 0.00 ATOM 1156 SG CYS 187 12.792-3.919 3.490 1.00 0.00 ATOM 1157 C CYS 187 11.573-6.644 0.764 1.00 0.00 ATOM 1158 O CYS 187 10.894-7.645 0.963 1.00 0.00 ATOM 1159 N PRO 188 12.550-6.605-0.160 1.00 0.00 ATOM 1160 CD PRO 188 13.391-5.438-0.465 1.00 0.00 ATOM 1161 CA PRO 188 12.896-7.753-0.999 1.00 0.00 ATOM 1162 HA PRO 188 12.036-8.123-1.539 1.00 0.00 ATOM 1163 CB PRO 188 13.932-7.200-1.989 1.00 0.00 ATOM 1164 1HB PRO 188 13.684-7.526-2.988 1.00 0.00 ATOM 1165 2HB PRO 188 14.913-7.566-1.723 1.00 0.00 ATOM 1166 QB PRO 188 14.298-7.546-2.356 1.00 0.00 ATOM 1167 CG PRO 188 13.852-5.714-1.866 1.00 0.00 ATOM 1168 1HG PRO 188 13. 141-5. 324-2.579 1.00 0.00

ATOM 1169 2HG PRO 188 14.827-5.278-2.033 1.00 0.00 ATOM 1170 QG PRO 188 13.984-5.301-2.306 1.00 0.00 ATOM 1171 1HD PRO 188 12.813-4.526-0.430 1.00 0.00 ATOM 1172 2HD PRO 188 14.233-5.380 0.207 1.00 0.00 ATOM 1173 QD PRO 188 13.523-4.953-0.112 1.00 0.00 ATOM 1174 C PRO 188 13.502-8.887-0.184 1.00 0.00 ATOM 1175 O PRO 188 14.540-8.707 0.467 1.00 0.00 ATOM 1176 N LEU 189 12.851-10.038-0.236 1.00 0.00 ATOM 1177 H LEU 189 12.038-10.098-0.782 1.00 0.00 ATOM 1178 CA LEU 189 13.302-11.220 0.472 1.00 0.00 ATOM 1179 HA LEU 189 14.058-10.919 1.182 1.00 0.00 ATOM 1180 CB LEU 189 12.138-11.875 1.217 1.00 0.00 ATOM 1181 1HB LEU 189 11.668-12.581 0.549 1.00 0.00 ATOM 1182 2HB LEU 189 11.420-11.109 1.468 1.00 0.00 ATOM 1183 QB LEU 189 11.544-11.845 1.008 1.00 0.00 ATOM 1184 CG LEU 189 12.523-12.615 2.499 1.00 0.00 ATOM 1185 HG LEU 189 13.387-13.234 2.304 1.00 0.00 ATOM 1186 QD1 LEU 189 12.973-11.398 3.857 1.00 0.00 ATOM 1187 QD2 LEU 189 11.118-13.732 3.059 1.00 0.00 ATOM 1188 CD1 LEU 189 12.888-11.630 3.598 1.00 0.00 ATOM 1189 1HD1 LEU 189 11.999-11.106 3.920 1.00 0.00 ATOM 1190 2HD1 LEU 189 13.607-10.921 3.218 1.00 0.00 ATOM 1191 3HD1 LEU 189 13.313-12.165 4.433 1.00 0.00 ATOM 1192 CD2 LEU 189 11.387-13.518 2.952 1.00 0.00 ATOM 1193 1HD2 LEU 189 11.061-14.128 2.123 1.00 0.00 ATOM 1194 2HD2 LEU 189 10.564-12.913 3.301 1.00 0.00 ATOM 1195 3HD2 LEU 189 11.731-14.155 3.753 1.00 0.00 ATOM 1196 QQD LEU 189 12.045-12.565 3.458 1.00 0.00 ATOM 1197 C LEU 189 13.911-12.207-0.514 1.00 0.00 ATOM 1198 OT1 LEU 189 14.865-12.912-0.132 1.00 0.00 ATOM 1199 OT2 LEU 189 13.430-12.256-1.668 1.00 0.00 TER ENDMDL MODEL 3 ATOM 1 N SER 124 13.960 17.252 0.397 1.00 0.00 ATOM 2 CA SER 124 13.975 15.894-0.191 1.00 0.00 ATOM 3 HA SER 124 14.255 15.963-1.231 1.00 0.00 ATOM 4 CB SER 124 15.015 15.073 0.568 1.00 0.00 ATOM 5 1HB SER 124 15.671 14.581-0.136 1.00 0.00 ATOM 6 2HB SER 124 14.514 14.331 1.176 1.00 0.00 ATOM 7 QB SER 124 15.092 14.456 0.520 1.00 0.00 ATOM 8 OG SER 124 15.790 15.914 1.411 1.00 0.00 ATOM 9 HG SER 124 16.395 15.375 1.938 1.00 0.00 ATOM 10 C SER 124 12.600 15.254-0.078 1.00 0.00 ATOM 11 O SER 124 11.687 15.850 0.491 1.00 0.00 ATOM 12 1HT SER 124 13.044 17.426 0.861 1.00 0.00 ATOM 13 2HT SER 124 14.106 17.966-0.342 1.00 0.00 ATOM 14 3HT SER 124 14.719 17.336 1.107 1.00 0.00 ATOM 15 N ASP 125 12.461 14.049-0.616 1.00 0.00 ATOM 16 H ASP 125 13.229 13.626-1.051 1.00 0.00 ATOM 17 CA ASP 125 11.195 13.330-0.571 1.00 0.00 ATOM 18 HA ASP 125 10.436 14.009-0.211 1.00 0.00 ATOM 19 CB ASP 125 10.811 12.847-1.975 1.00 0.00 ATOM 20 1HB ASP 125 11.597 12.214-2.360 1.00 0.00 ATOM 21 2HB ASP 125 10.690 13.701-2.624 1.00 0.00 ATOM 22 QB ASP 125 11.143 12.958-2.492 1.00 0.00 ATOM 23 CG ASP 125 9.519 12.058-1.982 1.00 0.00 ATOM 24 OD1 ASP 125 8.491 12.608-1.541 1.00 0.00 ATOM 25 OD2 ASP 125 9.541 10.882-2.395 1.00 0.00 ATOM 26 C ASP 125 11.288 12.142 0.380 1.00 0.00 ATOM 27 O ASP 125 12.386 11. 686 0.709 1.00 0.00 ATOM 28 N ALA 126 10.133 11.643 0.803 1.00 0.00 ATOM 29 H ALA 126 9.298 12.053 0.483 1.00 0.00 ATOM 30 CA ALA 126 10. 054 10.498 1.699 1.00 0.00 ATOM 31 HA ALA 126 10.887 9.844 1.485 1.00 0.00 ATOM 32 QB ALA 126 10.171 11.047 3.495 1.00 0.00 ATOM 33 CB ALA 126 10.150 10.943 3.152 1.00 0.00 ATOM 34 1HB ALA 126 9.454 10.370 3.748 1.00 0.00 ATOM 35 2HB ALA 126 9.907 11.992 3.224 1.00 0.00 ATOM 36 3HB ALA 126 11. 154 10.779 3.513 1.00 0.00 ATOM 37 C ALA 126 8.752 9.744 1.461 1.00 0.00 ATOM 38 O ALA 126 8.184 9.150 2.379 1.00 0.00

ATOM 39 N LEU 127 8.274 9.797 0.225 1.00 0.00 ATOM 40 H LEU 127 8.766 10.304-0.457 1.00 0.00 ATOM 41 CA LEU 127 7.028 9.148-0. 146 1.00 0.00 ATOM 42 HA LEU 127 6.528 8.847 0.759 1.00 0.00 ATOM 43 CB LEU 127 6.140 10.142-0. 899 1.00 0.00 ATOM 44 1HB LEU 127 6. 385 10.079-1.950 1.00 0.00 ATOM 45 2HB LEU 127 6.379 11.138-0.554 1.00 0.00 ATOM 46 QB LEU 127 6.382 10.609-1.252 1.00 0.00 ATOM 47 CG LEU 127 4.635 9.928-0.748 1.00 0.00 ATOM 48 HG LEU 127 4.451 8.923-0.394 1.00 0.00 ATOM 49 QD1 LEU 127 3.920 11.127 0.510 1.00 0.00 ATOM 50 QD2 LEU 127 3.775 10.128-2.409 1.00 0.00 ATOM 51 CD1 LEU 127 4.058 10.898 0.270 1.00 0.00 ATOM 52 1HD1 LEU 127 3.923 11.865-0.191 1.00 0.00 ATOM 53 2HD1 LEU 127 4.735 10.988 1.106 1.00 0.00 ATOM 54 3HD1 LEU 127 3.103 10.529 0. 616 1.00 0.00 ATOM 55 CD2 LEU 127 3.940 10.090-2.090 1.00 0.00 ATOM 56 1HD2 LEU 127 3.714 9.115-2.498 1.00 0.00 ATOM 57 2HD2 LEU 127 4.588 10.623-2.770 1.00 0.00 ATOM 58 3HD2 LEU 127 3.023 10.646-1.957 1.00 0.00 ATOM 59 QQD LEU 127 3.847 10.628-0.949 1.00 0.00 ATOM 60 C LEU 127 7.267 7.921-1.016 1.00 0.00 ATOM 61 O LEU 127 6.358 7.124-1.238 1.00 0.00 ATOM 62 N LEU 128 8.476 7.770-1.535 1.00 0.00 ATOM 63 H LEU 128 9.170 8.434-1.353 1.00 0.00 ATOM 64 CA LEU 128 8.764 6.638-2.397 1.00 0.00 ATOM 65 HA LEU 128 7.822 6.173-2.637 1.00 0.00 ATOM 66 CB LEU 128 9.418 7.124-3.700 1.00 0.00 ATOM 67 1HB LEU 128 10.490 7.092-3.567 1.00 0.00 ATOM 68 2HB LEU 128 9.128 8.154-3.855 1.00 0.00 ATOM 69 QB LEU 128 9.809 7.623-3.711 1.00 0.00 ATOM 70 CG LEU 128 9.070 6.330-4.975 1.00 0.00 ATOM 71 HG LEU 128 8.709 7.022-5.725 1.00 0.00 ATOM 72 QD1 LEU 128 10.594 5.479-5.674 1.00 0.00 ATOM 73 QD2 LEU 128 7.699 5.078-4.658 1.00 0.00 ATOM 74 CD1 LEU 128 10.302 5.642-5.539 1.00 0.00 ATOM 75 1HD1 LEU 128 10.715 6.241-6.338 1.00 0.00 ATOM 76 2HD1 LEU 128 10.028 4.671-5.923 1.00 0.00 ATOM 77 3HD1 LEU 128 11.041 5.525-4.759 1.00 0.00 ATOM 78 CD2 LEU 128 7.961 5.316-4.718 1.00 0.00 ATOM 79 1HD2 LEU 128 7.693 4.835-5.647 1.00 0.00 ATOM 80 2HD2 LEU 128 7.098 5.824-4.313 1.00 0.00 ATOM 81 3HD2 LEU 128 8.306 4.574-4.014 1.00 0.00 ATOM 82 QQD LEU 128 9.147 5.278-5.166 1.00 0.00 ATOM 83 C LEU 128 9.646 5.607-1.687 1.00 0.00 ATOM 84 O LEU 128 9.857 5.678-0.476 1.00 0.00 ATOM 85 N VAL 129 10.121 4.639-2.459 1.00 0.00 ATOM 86 H VAL 129 9.886 4.649-3.409 1.00 0.00 ATOM 87 CA VAL 129 10.953 3.544-1.965 1.00 0.00 ATOM 88 HA VAL 129 10.371 2.975-1.259 1.00 0.00 ATOM 89 CB VAL 129 11.346 2.609-3.132 1.00 0.00 ATOM 90 HB VAL 129 12.002 3.161-3.791 1.00 0.00 ATOM 91 QG1 VAL 129 12.287 1.103-2.515 1.00 0.00 ATOM 92 QG2 VAL 129 9.831 2.092-4.117 1.00 0.00 ATOM 93 CG1 VAL 129 12.106 1.391-2.633 1.00 0.00 ATOM 94 1HG1 VAL 129 11.764 0.513-3.158 1.00 0.00 ATOM 95 2HG1 VAL 129 11.936 1.268-1.573 1.00 0.00 ATOM 96 3HG1 VAL 129 13.162 1.529-2.813 1.00 0.00 ATOM 97 CG2 VAL 129 10.121 2.191-3.929 1.00 0.00 ATOM 98 1HG2 VAL 129 10.127 2.691-4.886 1.00 0.00 ATOM 99 2HG2 VAL 129 9.226 2.463-3.386 1.00 0.00 ATOM 100 3HG2 VAL 129 10.140 1.122-4.079 1.00 0.00 ATOM 101 QQG VAL 129 11.059 1.598-3.316 1.00 0.00 ATOM 102 C VAL 129 12.237 4.019-1.284 1.00 0.00 ATOM 103 O VAL 129 13.073 4.674-1.907 1.00 0.00 ATOM 104 N PRO 130 12.420 3.660 0.003 1.00 0.00 ATOM 105 CD PRO 130 11.476 2.868 0.812 1.00 0.00 ATOM 106 CA PRO 130 13.621 4.012 0.752 1.00 0.00 ATOM 107 HA PRO 130 13.894 5.046 0.596 1.00 0.00 ATOM 108 CB PRO 130 13.210 3.796 2.209 1.00 0.00 ATOM 109 1HB PRO 130 12.839 4.722 2.622 1.00 0.00 ATOM 110 2HB PRO 130 14.065 3.459 2.776 1.00 0.00

ATOM 111 QB PRO 130 13.452 4.091 2.699 1.00 0.00 ATOM 112 CG PRO 130 12.142 2.755 2.161 1.00 0.00 ATOM 113 1HG PRO 130 11.423 2.934 2.947 1.00 0.00 ATOM 114 2HG PRO 130 12.582 1.775 2.275 1.00 0.00 ATOM 115 QG PRO 130 12.002 2.355 2.611 1.00 0.00 ATOM 116 1HD PRO 130 10.528 3.377 0.903 1.00 0.00 ATOM 117 2HD PRO 130 11.337 1.887 0.381 1.00 0.00 ATOM 118 QD PRO 130 10.932 2.632 0.642 1.00 0.00 ATOM 119 C PRO 130 14.805 3. 111 0.377 1.00 0.00 ATOM 120 O PRO 130 14.797 2.462-0.668 1.00 0.00 ATOM 121 N ASP 131 15.824 3.088 1.228 1.00 0.00 ATOM 122 H ASP 131 15.779 3.636 2.036 1.00 0.00 ATOM 123 CA ASP 131 17.025 2.288 0.976 1.00 0.00 ATOM 124 HA ASP 131 17.260 2.370-0.076 1.00 0.00 ATOM 125 CB ASP 131 18.199 2.854 1.781 1.00 0.00 ATOM 126 1HB ASP 131 17.948 2.837 2.830 1.00 0.00 ATOM 127 2HB ASP 131 18.381 3.873 1.476 1.00 0.00 ATOM 128 QB ASP 131 18.164 3.355 2.153 1.00 0.00 ATOM 129 CG ASP 131 19.475 2.063 1.583 1.00 0.00 ATOM 130 OD1 ASP 131 19.996 1.519 2.581 1.00 0.00 ATOM 131 OD2 ASP 131 19.945 1.970 0.435 1.00 0.00 ATOM 132 C ASP 131 16.844 0.802 1.319 1.00 0. 00 ATOM 133 O ASP 131 17.483-0.064 0.720 1.00 0.00 ATOM 134 N LYS+ 132 16.016 0.493 2.309 1.00 0.00 ATOM 135 H LYS+ 132 15.547 1.206 2.788 1.00 0.00 ATOM 136 CA LYS+ 132 15.840-0.902 2.716 1.00 0.00 ATOM 137 HA LYS+ 132 16.717-1.437 2.387 1.00 0.00 ATOM 138 CB LYS+ 132 15.761-1.006 4.240 1.00 0.00 ATOM 139 1HB LYS+ 132 15.320-1.957 4.502 1.00 0.00 ATOM 140 2HB LYS+ 132 15.130-0.213 4.613 1.00 0.00 ATOM 141 QB LYS+ 132 15.225-1.085 4.557 1.00 0.00 ATOM 142 CG LYS+ 132 17. 116-0.902 4.928 1.00 0.00 ATOM 143 1HG LYS+ 132 16.980-1.056 5.989 1.00 0.00 ATOM 144 2HG LYS+ 132 17.521 0.085 4.757 1.00 0.00 ATOM 145 QG LYS+ 132 17.250-0.485 5.373 1.00 0.00 ATOM 146 CD LYS+ 132 18.103-1.936 4.402 1.00 0.00 ATOM 147 1HD LYS+ 132 17.650-2.468 3.579 1.00 0.00 ATOM 148 2HD LYS+ 132 18.336-2.630 5.196 1.00 0.00 ATOM 149 QD LYS+ 132 17.993-2.549 4.387 1.00 0.00 ATOM 150 CE LYS+ 132 19.396-1.284 3.926 1.00 0.00 ATOM 151 1HE LYS+ 132 20.225-1.927 4.183 1.00 0.00 ATOM 152 2HE LYS+ 132 19.510-0.337 4.432 1.00 0.00 ATOM 153 QE LYS+ 132 19.867-1.132 4.307 1.00 0.00 ATOM 154 NZ LYS+ 132 19.407-1.041 2.455 1.00 0.00 ATOM 155 1HZ LYS+ 132 19.912-1.802 1.961 1.00 0.00 ATOM 156 2HZ LYS+ 132 19.890-0.128 2.249 1.00 0.00 ATOM 157 3HZ LYS+ 132 18.434-0.980 2.082 1.00 0.00 ATOM 158 QZ LYS+ 132 19.412-0.970 2.097 1.00 0.00 ATOM 159 C LYS+ 132 14.622-1.573 2.081 1.00 0.00 ATOM 160 O LYS+ 132 14.762-2.502 1.289 1.00 0.00 ATOM 161 N CYS 133 13.431-1.133 2.453 1. 00 0.00 ATOM 162 H CYS 133 13.370-0.412 3.105 1.00 0.00 ATOM 163 CA CYS 133 12.208-1.730 1.930 1.00 0. 00 ATOM 164 HA CYS 133 12.426-2.750 1.650 1.00 0.00 ATOM 165 CB CYS 133 11.106-1.721 2.996 1.00 0.00 ATOM 166 1HB CYS 133 10. 155-1. 894 2.511 1.00 0. 00 ATOM 167 2HB CYS 133 11.082-0.748 3.464 1.00 0.00 ATOM 168 QB CYS 133 10.618-1.321 2.987 1.00 0.00 ATOM 169 SG CYS 133 11.274-2.957 4.328 1.00 0.00 ATOM 170 C CYS 133 11.717-0.970 0.704 1.00 0.00 ATOM 171 O CYS 133 12.229 0.092 0.379 1.00 0.00 ATOM 172 N LYS+ 134 10.710-1.518 0.040 1.00 0.00 ATOM 173 H LYS+ 134 10.335-2.367 0.358 1.00 0.00 ATOM 174 CA LYS+ 134 10.128-0.895-1.136 1.00 0.00 ATOM 175 HA LYS+ 134 10.824-0.153-1.501 1.00 0.00 ATOM 176 CB LYS+ 134 9.877-1.938-2.231 1.00 0.00 ATOM 177 1HB LYS+ 134 9.063-2.578-1.920 1.00 0.00 ATOM 178 2HB LYS+ 134 10.768-2.537-2.351 1.00 0.00 ATOM 179 QB LYS+ 134 9.915-2. 557-2.136 1.00 0.00 ATOM 180 CG LYS+ 134 9.521-1.337-3.583 1.00 0.00 ATOM 181 1HG LYS+ 134 10.371-0.778-3.950 1.00 0.00 ATOM 182 2HG LYS+ 134 8.678-0.676-3.459 1.00 0.00

ATOM 183 QG LYS+ 134 9.524-0.727-3.705 1.00 0.00 ATOM 184 CD LYS+ 134 9.161-2.414-4.596 1.00 0.00 ATOM 185 1HD LYS+ 134 8.490-3.123-4.131 1.00 0.00 ATOM 186 2HD LYS+ 134 10.064-2.921-4.903 1.00 0.00 ATOM 187 QD LYS+ 134 9.277-3.022-4.517 1.00 0.00 ATOM 188 CE LYS+ 134 8.485-1.826-5.828 1.00 0.00 ATOM 189 1HE LYS+ 134 7.810-2.565-6.238 1.00 0.00 ATOM 190 2HE LYS+ 134 9.244-1.590-6.561 1.00 0.00 ATOM 191 QE LYS+ 134 8.527-2.077-6.400 1.00 0.00 ATOM 192 NZ LYS+ 134 7.716-0.588-5.511 1.00 0.00 ATOM 193 1HZ LYS+ 134 8.337 0.118-5.068 1.00 0.00 ATOM 194 2HZ LYS+ 134 6.937-0.809-4.854 1.00 0.00 ATOM 195 3HZ LYS+ 134 7.312-0.184-6.381 1.00 0.00 ATOM 196 QZ LYS+ 134 7.528-0.292-5.435 1.00 0.00 ATOM 197 C LYS+ 134 8.826-0.211-0.754 1.00 0.00 ATOM 198 O LYS+ 134 7.872-0.869-0.353 1.00 0.00 ATOM 199 N PHE 135 8.796 1.105-0.867 1.00 0.00 ATOM 200 H PHE 135 9.594 1.576-1.186 1.00 0.00 ATOM 201 CA PHE 135 7.610 1.873-0.513 1.00 0.00 ATOM 202 HA PHE 135 7.051 1.309 0.220 1.00 0.00 ATOM 203 CB PHE 135 8.026 3.215 0.095 1.00 0.00 ATOM 204 1HB PHE 135 8.267 3.899-0.707 1.00 0.00 ATOM 205 2HB PHE 135 8.906 3.065 0.701 1.00 0.00 ATOM 206 QB PHE 135 8.586 3.482-0.003 1.00 0.00 ATOM 207 QD PHE 135 6.874 3.949 1.059 1.00 0.00 ATOM 208 QE PHE 135 5.203 5.048 2.489 1.00 0.00 ATOM 209 QR PHE 135 5.704 4.718 2.061 1.00 0.00 ATOM 210 CG PHE 135 6.989 3.873 0.963 1.00 0.00 ATOM 211 CD1 PHE 135 5.830 3.210 1.331 1.00 0.00 ATOM 212 1HD PHE 135 5.663 2.200 0.986 1.00 0.00 ATOM 213 CE1 PHE 135 4.890 3.826 2.134 1.00 0.00 ATOM 214 1HE PHE 135 3.990 3.298 2.416 1.00 0.00 ATOM 215 CZ PHE 135 5.099 5.116 2.578 1.00 0.00 ATOM 216 HZ PHE 135 4.364 5.597 3.207 1.00 0.00 ATOM 217 CE2 PHE 135 6.249 5.788 2.217 1.00 0.00 ATOM 218 2HE PHE 135 6.416 6.798 2.563 1.00 0.00 ATOM 219 CD2 PHE 135 7.186 5.168 1.416 1.00 0.00 ATOM 220 2HD PHE 135 8.086 5.697 1.133 1.00 0.00 ATOM 221 C PHE 135 6.735 2.107-1.735 1.00 0.00 ATOM 222 O PHE 135 7.185 2.651-2.743 1.00 0.00 ATOM 223 N LEU 136 5.484 1.694-1.633 1.00 0.00 ATOM 224 H LEU 136 5.186 1.268-0.797 1.00 0.00 ATOM 225 CA LEU 136 4.531 1.859-2.711 1.00 0.00 ATOM 226 HA LEU 136 5.043 2.326-3.539 1.00 0.00 ATOM 227 CB LEU 136 3.975 0.506-3.158 1. 00 0.00 ATOM 228 1HB LEU 136 3.147 0.688-3.829 1.00 0.00 ATOM 229 2HB LEU 136 3.600-0.011-2.285 1.00 0.00 ATOM 230 QB LEU 136 3.373 0.339-3.057 1.00 0.00 ATOM 231 CG LEU 136 4.977-0.404-3.870 1.00 0.00 ATOM 232 HG LEU 136 5.748 0.205-4.317 1.00 0.00 ATOM 233 QD1 LEU 136 5.791-1.577-2.646 1.00 0.00 ATOM 234 QD2 LEU 136 4.130-1.377-5.237 1.00 0.00 ATOM 235 CD1 LEU 136 5.636-1.352-2.881 1.00 0.00 ATOM 236 1HD1 LEU 136 6.409-0.828-2.338 1.00 0.00 ATOM 237 2HD1 LEU 136 6.070-2.186-3.413 1.00 0.00 ATOM 238 3HD1 LEU 136 4.894-1.717-2.186 1.00 0.00 ATOM 239 CD2 LEU 136 4.294-1. 190-4.976 1.00 0.00 ATOM 240 1HD2 LEU 136 3.233-1.238-4.778 1.00 0.00 ATOM 241 2HD2 LEU 136 4.698-2.191-5.009 1.00 0.00 ATOM 242 3HD2 LEU 136 4.460-0.701-5.924 1.00 0.00 ATOM 243 QQD LEU 136 4.960-1.477-3.942 1.00 0.00 ATOM 244 C LEU 136 3.409 2.770-2.249 1.00 0.00 ATOM 245 O LEU 136 2.314 2.317-1.927 1.00 0.00 ATOM 246 N HIS+ 137 3.706 4.057-2.208 1.00 0.00 ATOM 247 H HIS+ 137 4.604 4.345-2.469 1.00 0.00 ATOM 248 CA HIS+ 137 2.746 5.059-1.781 1.00 0.00 ATOM 249 HA HIS+ 137 2.029 4.592-1.112 1.00 0.00 ATOM 250 CB HIS+ 137 3.479 6.190-1.055 1.00 0.00 ATOM 251 1HB HIS+ 137 3.961 6.819-1.791 1.00 0.00 ATOM 252 2HB HIS+ 137 4.234 5.762-0.413 1.00 0.00 ATOM 253 QB HIS+ 137 4.097 6.291-1.102 1.00 0.00 ATOM 254 CG HIS+ 137 2.608 7.063-0.209 1.00 0.00

ATOM 255 ND1 HIS+ 137 1.489 7.715-0.680 1.00 0.00 ATOM 256 CD2 HIS+ 137 2.702 7.382 1.100 1.00 0.00 ATOM 257 1HD HIS+ 137 1.149 7.694-1.606 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.935 8.392 0.306 1.00 0.00 ATOM 259 NE2 HIS+ 137 1.648 8.206 1.405 1.00 0.00 ATOM 260 2HD HIS+ 137 3.466 7.043 1.786 1.00 0.00 ATOM 261 1HE HIS+ 137 0.040 8.995 0.230 1.00 0.00 ATOM 262 2HE HIS+ 137 1.287 8.314 2.318 1.00 0.00 ATOM 263 C HIS+ 137 2.034 5.616-3.001 1.00 0.00 ATOM 264 O HIS+ 137 2.570 6.483-3.693 1.00 0.00 ATOM 265 N GLN 138 0.845 5.112-3.279 1.00 0.00 ATOM 266 H GLN 138 0.464 4.410-2.696 1.00 0.00 ATOM 267 CA GLN 138 0.097 5.572-4.439 1.00 0.00 ATOM 268 HA GLN 138 0.485 6.543-4.709 1.00 0. 00 ATOM 269 CB GLN 138 0.298 4.617-5.618 1.00 0.00 ATOM 270 1HB GLN 138-0.578 4.652-6.249 1.00 0.00 ATOM 271 2HB GLN 138 0.414 3.615-5.237 1.00 0.00 ATOM 272 QB GLN 138-0.082 4.134-5.743 1.00 0.00 ATOM 273 CG GLN 138 1.516 4.949-6.471 1.00 0.00 ATOM 274 1HG GLN 138 1.789 5.980-6.297 1.00 0.00 ATOM 275 2HG GLN 138 1.258 4.817-7.512 1.00 0.00 ATOM 276 QG GLN 138 1.523 5.399-6.905 1. 00 0.00 ATOM 277 CD GLN 138 2.715 4.071-6.157 1.00 0.00 ATOM 278 OE1 GLN 138 2.641 2.846-6.243 1.00 0.00 ATOM 279 NE2 GLN 138 3.830 4.690-5.788 1.00 0. 00 ATOM 280 1HE2 GLN 138 3.825 5.671-5.737 1.00 0.00 ATOM 281 2HE2 GLN 138 4.613 4.143-5.579 1.00 0.00 ATOM 282 QE2 GLN 138 4.219 4.907-5.658 1.00 0.00 ATOM 283 C GLN 138-1.384 5.717-4.124 1.00 0.00 ATOM 284 O GLN 138-1.981 4.875-3.447 1.00 0.00 ATOM 285 N GLU 139-1.963 6.797-4.618 1.00 0.00 ATOM 286 H GLU 139-1.424 7.425-5.140 1.00 0.00 ATOM 287 CA GLU 139-3.370 7.089-4.398 1.00 0.00 ATOM 288 HA GLU 139-3.676 6. 568-3.504 1.00 0.00 ATOM 289 CB GLU 139-3.576 8.596-4.190 1.00 0.00 ATOM 290 1HB GLU 139-4.130 8.747-3.275 1.00 0.00 ATOM 291 2HB GLU 139-4.152 8.985-5.017 1.00 0.00 ATOM 292 QB GLU 139-4. 141 8.866-4.146 1.00 0.00 ATOM 293 CG GLU 139-2.279 9.395-4.096 1.00 0.00 ATOM 294 1HG GLU 139-2.507 10.443-4.222 1.00 0.00 ATOM 295 2HG GLU 139-1.616 9.076-4.885 1.00 0.00 ATOM 296 QG GLU 139-2.062 9.760-4.554 1.00 0.00 ATOM 297 CD GLU 139-1.570 9.212-2.768 1.00 0.00 ATOM 298 OE1 GLU 139-0.458 8.643-2.764 1.00 0.00 ATOM 299 OE2 GLU 139-2.130 9.627-1.735 1.00 0.00 ATOM 300 C GLU 139-4.217 6.595-5.568 1.00 0.00 ATOM 301 O GLU 139-4.191 7.166-6.660 1.00 0.00 ATOM 302 N ARG+ 140-4.971 5. 533-5. 334 1.00 0.00 ATOM 303 H ARG+ 140-4.957 5.124-4.441 1.00 0.00 ATOM 304 CA ARG+ 140-5.833 4.960-6.357 1.00 0.00 ATOM 305 HA ARG+ 140-5.436 5.239-7.320 1.00 0.00 ATOM 306 CB ARG+ 140-5.849 3.429-6.236 1.00 0. 00 ATOM 307 1HB ARG+ 140-6.419 3.158-5.356 1.00 0.00 ATOM 308 2HB ARG+ 140-4.835 3.079-6.115 1.00 0.00 ATOM 309 QB ARG+ 140-5.627 3.119-5.736 1.00 0.00 ATOM 310 CG ARG+ 140-6.459 2.715-7.430 1.00 0.00 ATOM 311 1HG ARG+ 140-7.303 3.289-7.786 1.00 0.00 ATOM 312 2HG ARG+ 140-6.797 1.738-7.115 1.00 0.00 ATOM 313 QG ARG+ 140-7.050 2.514-7.451 1.00 0.00 ATOM 314 CD ARG+ 140-5.460 2.546-8.566 1.00 0.00 ATOM 315 1HD ARG+ 140-4.777 1.748-8.313 1.00 0.00 ATOM 316 2HD ARG+ 140-4.909 3.467-8.689 1.00 0.00 ATOM 317 QD ARG+ 140-4.843 2.608-8.501 1.00 0.00 ATOM 318 NE ARG+ 140-6.131 2.218-9.823 1.00 0.00 ATOM 319 HE ARG+ 140-6.138 1.275-10.100 1.00 0.00 ATOM 320 CZ ARG+ 140-6.768 3.116-10.576 1.00 0.00 ATOM 321 NH1 ARG+ 140-6.734 4.401-10.244 1.00 0.00 ATOM 322 1HH1 ARG+ 140-6.226 4.698-9.439 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.254 5.077-10.784 1.00 0.00 ATOM 324 QH1 ARG+ 140-6.740 4.888-10.112 1.00 0.00 ATOM 325 NH2 ARG+ 140-7.424 2.731-11.664 1.00 0.00 ATOM 326 1HH2 ARG+ 140-7.440 1.769-11.930 1.00 0.00

ATOM 327 2HH2 ARG+ 140-7.940 3.406-12.206 1.00 0.00 ATOM 328 QH2 ARG+ 140-7.690 2.588-12.068 1.00 0.00 ATOM 329 C ARG+ 140-7. 246 5.521-6.220 1.00 0.00 ATOM 330 O ARG+ 140-8.115 4.899-5.612 1.00 0.00 ATOM 331 N MET 141-7.464 6.707-6.784 1.00 0.00 ATOM 332 H MET 141-6. 724 7.152-7.248 1.00 0.00 ATOM 333 CA MET 141-8.767 7.376-6.723 1.00 0.00 ATOM 334 HA MET 141-9.107 7.338-5.700 1.00 0.00 ATOM 335 CB MET 141-8.614 8.843-7.139 1.00 0.00 ATOM 336 1HB MET 141-8.728 8.912-8.212 1.00 0.00 ATOM 337 2HB MET 141-7. 625 9.181-6.869 1.00 0.00 ATOM 338 QB MET 141-8.177 9.047-7.541 1.00 0.00 ATOM 339 CG MET 141-9.628 9.775-6.494 1.00 0.00 ATOM 340 1HG MET 141-10.597 9.298-6.514 1.00 0.00 ATOM 341 2HG MET 141-9. 669 10.691-7.066 1.00 0.00 ATOM 342 QG MET 141-10.133 9.995-6.790 1.00 0.00 ATOM 343 SD MET 141-9.214 10.178-4.788 1.00 0.00 ATOM 344 QE MET 141-7.505 11.452-5.083 1.00 0.00 ATOM 345 CE MET 141-7.792 11.239-5.033 1.00 0.00 ATOM 346 1HE MET 141-7.272 10.943-5.933 1.00 0.00 ATOM 347 2HE MET 141-7.125 11.149-4.187 1.00 0. 00 ATOM 348 3HE MET 141-8.118 12.264-5.127 1.00 0.00 ATOM 349 C MET 141-9.811 6.695-7.614 1.00 0. 00 ATOM 350 O MET 141-10.644 7.362-8.229 1.00 0. 00 ATOM 351 N ASP 142-9.778 5.372-7.662 1.00 0.00 ATOM 352 H ASP 142-9.104 4.895-7.134 1.00 0.00 ATOM 353 CA ASP 142-10.721 4.605-8.455 1.00 0.00 ATOM 354 HA ASP 142-11.406 5.293-8.928 1.00 0.00 ATOM 355 CB ASP 142-9.989 3.803-9.528 1.00 0.00 ATOM 356 1HB ASP 142-10.595 2.955-9.801 1.00 0.00 ATOM 357 2HB ASP-142-9. 052 3.452-9.126 1.00 0.00 ATOM 358 QB ASP 142-9.824 3.204-9.464 1.00 0.00 ATOM 359 CG ASP 142-9.698 4.605-10.778 1.00 0.00 ATOM 360 OD1 ASP 142-9.139 5.713-10.657 1.00 0.00 ATOM 361 OD2 ASP 142-9.974 4.100-11.881 1. 00 0.00 ATOM 362 C ASP 142-11.497 3.647-7.567 1.00 0.00 ATOM 363 O ASP 142-12.728 3.649-7.549 1.00 0.00 ATOM 364 N VAL 143-10.763 2.826-6.830 1.00 0.00 ATOM 365 H VAL 143-9.787 2.875-6.890 1.00 0.00 ATOM 366 CA VAL 143-11.370 1.843-5.946 1.00 0.00 ATOM 367 HA VAL 143-12.354 1.614-6.329 1.00 0.00 ATOM 368 CB VAL 143-10.540 0.538-5.921 1.00 0.00 ATOM 369 HB VAL 143-9.854 0.588-5.084 1.00 0.00 ATOM 370 QG1 VAL 143-11.649-0.958-5.676 1.00 0.00 ATOM 371 QG2 VAL 143-9.531 0.348-7.498 1.00 0.00 ATOM 372 CG1 VAL 143-11.438-0.671-5.722 1.00 0.00 ATOM 373 1HG1 VAL 143-11.604-0.827-4.666 1.00 0.00 ATOM 374 2HG1 VAL 143-10. 959-1.542-6.144 1.00 0.00 ATOM 375 3HG1 VAL 143-12.382-0.504-6.216 1.00 0.00 ATOM 376 CG2 VAL 143-9.723 0.385-7.196 1.00 0.00 ATOM 377 1HG2 VAL 143-9.866-0.608-7.597 1.00 0.00 ATOM 378 2HG2 VAL 143-8.678 0.536-6.974 1.00 0.00 ATOM 379 3HG2 VAL 143-10.048 1.117-7.921 1.00 0.00 ATOM 380 QQG VAL 143-10. 590-0. 305-6.587 1.00 0.00 ATOM 381 C VAL 143-11.507 2.399-4.527 1.00 0.00 ATOM 382 O VAL 143-10.794 3.322-4.144 1.00 0.00 ATOM 383 N CYS 144-12.434 1.838-3.759 1.00 0.00 ATOM 384 H CYS 144-12.977 1.107-4.124 1.00 0.00 ATOM 385 CA CYS 144-12.670 2.277-2.386 1.00 0.00 ATOM 386 HA CYS 144-11.749 2.700-2.003 1.00 0.00 ATOM 387 CB CYS 144-13.765 3.340-2.340 1.00 0.00 ATOM 388 1HB CYS 144-14.678 2.887-1.978 1.00 0.00 ATOM 389 2HB CYS 144-13.929 3.723-3.335 1.00 0.00 ATOM 390 QB CYS 144-14.304 3.305-2.657 1.00 0.00 ATOM 391 SG CYS 144-13.378 4.752-1.257 1.00 0.00 ATOM 392 C CYS 144-13.063 1.099-1. 514 1.00 0.00 ATOM 393 O CYS 144-14.247 0.799-1.363 1.00 0.00 ATOM 394 N GLU 145-12.069 0.428-0. 954 1.00 0.00 ATOM 395 H GLU 145-11.145 0.706-1. 118 1.00 0.00 ATOM 396 CA GLU 145-12.312-0.724-0.118 1.00 0.00 ATOM 397 HA GLU 145-13.369-0.931-0.151 1.00 0.00 ATOM 398 CB GLU 145-11.574-1.925-0.679 1.00 0.00

ATOM 399 1HB GLU 145-11.272-2.568 0.132 1.00 0.00 ATOM 400 2HB GLU 145-10.690-1.580-1.203 1.00 0.00 ATOM 401 QB GLU 145-10.981-2.074-0.536 1. 00 0.00 ATOM 402 CG GLU 145-12.438-2.728-1.630 1.00 0.00 ATOM 403 1HG GLU 145-11.913-3.629-1.910 1.00 0.00 ATOM 404 2HG GLU 145-12.641-2.135-2.510 1.00 0.00 ATOM 405 QG GLU 145-12.277-2.882-2.210 1.00 0.00 ATOM 406 CD GLU 145-13.750-3.109-0.983 1.00 0.00 ATOM 407 OE1 GLU 145-14.793-2.548-1.367 1.00 0.00 ATOM 408 OE2 GLU 145-13.730-3.934-0.048 1.00 0.00 ATOM 409 C GLU 145-11.916-0.484 1.323 1.00 0.00 ATOM 410 O GLU 145-11.462 0.600 1.690 1.00 0.00 ATOM 411 N THR 146-12.114-1.509 2.131 1.00 0.00 ATOM 412 H THR 146-12.490-2.336 1.764 1.00 0.00 ATOM 413 CA THR 146-11.812-1.447 3.544 1.00 0.00 ATOM 414 HA THR 146-12.108-0.473 3.907 1.00 0.00 ATOM 415 CB THR 146-12.624-2.519 4.272 1.00 0.00 ATOM 416 HB THR 146-12.041-3.429 4.316 1.00 0.00 ATOM 417 QG2 THR 146-13.092-2.048 6.026 1.00 0.00 ATOM 418 OG1 THR 146-13.826-2.793 3.565 1.00 0.00 ATOM 419 1HG THR 146-14. 442-3.251 4.147 1.00 0. 00 ATOM 420 CG2 THR 146-13.001-2.140 5.688 1.00 0. 00 ATOM 421 1HG2 THR 146-13.330-1.109 5.712 1.00 0.00 ATOM 422 2HG2 THR 146-12.144-2.257 6. 334 1.00 0.00 ATOM 423 3HG2 THR 146-13.800-2.778 6.034 1.00 0.00 ATOM 424 C THR 146-10.317-1.632 3.790 1.00 0.00 ATOM 425 O THR 146-9.569-2.016 2.887 1.00 0.00 ATOM 426 N HIS+ 147-9.901-1.351 5.021 1.00 0.00 ATOM 427 H HIS+ 147-10.564-1.047 5.679 1.00 0.00 ATOM 428 CA HIS+ 147-8.504-1.467 5. 439 1.00 0.00 ATOM 429 HA HIS+ 147-7.942-0.681 4.959 1.00 0.00 ATOM 430 CB HIS+ 147-8.420-1.286 6. 959 1.00 0.00 ATOM 431 1HB HIS+ 147-8.364-2.260 7. 424 1.00 0.00 ATOM 432 2HB HIS+ 147-9.311-0.783 7. 303 1.00 0.00 ATOM 433 QB HIS+ 147-8.838-1.521 7. 363 1.00 0.00 ATOM 434 CG HIS+ 147-7.243-0.490 7.419 1.00 0.00 ATOM 435 ND1 HIS+ 147-7.361 0.693 8.114 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.917-0.717 7. 286 1.00 0.00 ATOM 437 1HD HIS+ 147-8.207 1.128 8.372 1.00 0.00 ATOM 438 CE1 HIS+ 147-6.155 1.162 8. 387 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.258 0.325 7. 895 1.00 0.00 ATOM 440 2HD HIS+ 147-5.458-1.558 6.783 1.00 0.00 ATOM 441 1HE HIS+ 147-5.939 2.076 8.918 1.00 0.00 ATOM 442 2HE HIS+ 147-4.307 0.536 7.774 1. 00 0.00 ATOM 443 C HIS+ 147-7.903-2.820 5.059 1. 00 0.00 ATOM 444 O HIS+ 147-6. 736-2.908 4.676 1.00 0.00 ATOM 445 N LEU 148-8.705-3.869 5.188 1.00 0.00 ATOM 446 H LEU 148-9.620-3.730 5.510 1.00 0.00 ATOM 447 CA LEU 148-8.259-5.223 4.885 1.00 0.00 ATOM 448 HA LEU 148-7.350-5.398 5.439 1.00 0.00 ATOM 449 CB LEU 148-9.309-6.238 5.340 1.00 0.00 ATOM 450 1HB LEU 148-10.003-6.396 4.528 1.00 0.00 ATOM 451 2HB LEU 148-9.849-5.818 6.177 1.00 0.00 ATOM 452 QB LEU 148-9.926-6.107 5.352 1.00 0.00 ATOM 453 CG LEU 148-8.751-7.598 5.761 1.00 0.00 ATOM 454 HG LEU 148-7.678-7.525 5.860 1.00 0.00 ATOM 455 QD1 LEU 148-9.453-8.116 7.425 1.00 0.00 ATOM 456 QD2 LEU 148-9.127-8.899 4.455 1.00 0.00 ATOM 457 CD1 LEU 148-9.318-8.016 7.106 1.00 0. 00 ATOM 458 lADl LEU 148-8. 911-8. 977 7. 385 1.00 0.00 ATOM 459 2HD1 LEU 148-10.394-8.087 7.038 1.00 0.00 ATOM 460 3HD1 LEU 148-9.052-7.283 7.853 1.00 0.00 ATOM 461 CD2 LEU 148-9.055-8.649 4.706 1.00 0. 00 ATOM 462 1HD2 LEU 148-10.036-8.472 4.291 1.00 0.00 ATOM 463 2HD2 LEU 148-9.028-9.630 5.157 1.00 0.00 ATOM 464 3HD2 LEU 148-8.316-8. 595 3.919 1.00 0.00 ATOM 465 QQD LEU 148-9.290-8.507 5.940 1.00 0.00 ATOM 466 C LEU 148-7.966-5.421 3.401 1.00 0.00 ATOM 467 O LEU 148-6.935-5.990 3.050 1.00 0.00 ATOM 468 N HIS+ 149-8.875-4.978 2.531 1.00 0.00 ATOM 469 H HIS+ 149-9.689-4.547 2.863 1.00 0.00 ATOM 470 CA HIS+ 149-8. 688-5. 154 1.091 1.00 0.00

ATOM 471 HA HIS+ 149-8.649-6.219 0.914 1.00 0.00 ATOM 472 CB HIS+ 149-9.854-4.584 0.285 1.00 0.00 ATOM 473 1HB HIS+ 149-9.503-3.757-0.317 1.00 0.00 ATOM 474 2HB HIS+ 149-10.626-4.231 0.954 1.00 0.00 ATOM 475 QB HIS+ 149-10.065-3.994 0.318 1.00 0.00 ATOM 476 CG HIS+ 149-10.451-5.605-0.636 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.806-5.733-0.856 1.00 0.00 ATOM 478 CD2 HIS+ 149-9.859-6.563-1.390 1.00 0.00 ATOM 479 1HD HIS+ 149-12.515-5.161-0.461 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.022-6.726-1.702 1.00 0.00 ATOM 481 NE2 HIS+ 149-10.856-7.245-2.041 1.00 0.00 ATOM 482 2HD HIS+ 149-8.796-6.756-1.464 1.00 0.00 ATOM 483 1HE HIS+ 149-12.988-7.056-2.056 1.00 0.00 ATOM 484 2HE HIS+ 149-10.722-7.950-2.709 1.00 0.00 ATOM 485 C HIS+ 149-7.374-4.562 0.607 1.00 0.00 ATOM 486 O HIS+ 149-6. 588-5.259-0.024 1.00 0.00 ATOM 487 N TRP 150-7.127-3.291 0.901 1.00 0.00 ATOM 488 H TRP 150-7. 791-2.773 1.408 1.00 0.00 ATOM 489 CA TRP 150-5.880-2.653 0.476 1.00 0.00 ATOM 490 HA TRP 150-5.814-2.734-0.600 1.00 0.00 ATOM 491 CB TRP 150-5. 840-1.182 0.883 1.00 0.00 ATOM 492 1HB TRP 150-4.868-0.780 0.635 1.00 0.00 ATOM 493 2HB TRP 150-5.987-1.110 1.950 1.00 0. 00 ATOM 494 QB TRP 150-5.428-0.945 1.292 1.00 0.00 ATOM 495 CG TRP 150-6. 874-0.327 0.222 1.00 0.00 ATOM 496 CD1 TRP 150-7. 306 0.891 0.652 1.00 0.00 ATOM 497 CD2 TRP 150-7. 601-0.608-0.983 1.00 0.00 ATOM 498 CE3 TRP 150-7.617-1.673-1.888 1.00 0.00 ATOM 499 CE2 TRP 150-8.452 0.485-1.213 1.00 0.00 ATOM 500 NE1 TRP 150-8.256 1.382-0.203 1.00 0.00 ATOM 501 HD TRP 150-6.945 1.384 1.543 1.00 0.00 ATOM 502 3HE TRP 150-6.981-2.531-1.751 1.00 0.00 ATOM 503 CZ3 TRP 150-8.466-1.613-2.969 1.00 0.00 ATOM 504 CZ2 TRP 150-9.305 0.543-2.306 1.00 0.00 ATOM 505 1HE TRP 150-8.722 2.239-0.105 1.00 0.00 ATOM 506 3HZ TRP 150-8.496-2.430-3.673 1.00 0.00 ATOM 507 CH2 TRP 150-9.298-0.513-3.170 1.00 0.00 ATOM 508 2HZ TRP 150-9.955 1.389-2.480 1.00 0.00 ATOM 509 HH TRP 150-9.948-0.510-4.032 1.00 0.00 ATOM 510 C TRP 150-4.685-3.368 1.067 1.00 0.00 ATOM 511 O TRP 150-3.659-3.486 0.418 1.00 0.00 ATOM 512 N HIS+ 151-4.829-3.861 2.289 1.00 0.00 ATOM 513 H HIS+ 151-5.684-3.748 2.758 1.00 0.00 ATOM 514 CA HIS+ 151-3.752-4.592 2.936 1.00 0.00 ATOM 515 HA HIS+ 151-2.882-3.953 2.968 1.00 0.00 ATOM 516 CB HIS+ 151-4.165-4.977 4.369 1.00 0.00 ATOM 517 1HB HIS+ 151-5.093-5.530 4.323 1.00 0.00 ATOM 518 2HB HIS+ 151-4.326-4.075 4.938 1.00 0.00 ATOM 519 QB HIS+ 151-4. 710-4.802 4.630 1.00 0.00 ATOM 520 CG HIS+ 151-3.171-5.816 5.125 1.00 0.00 ATOM 521 ND1 HIS+ 151-2. 750-5.512 6.399 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.555-6.979 4.801 1.00 0.00 ATOM 523 1HD HIS+ 151-3.015-4.722 6.919 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.924-6.451 6.824 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.791-7.359 5.876 1.00 0.00 ATOM 526 2HD HIS+ 151-2.625-7.494 3.850 1.00 0.00 ATOM 527 1HE HIS+ 151-1.430-6.467 7.786 1.00 0.00 ATOM 528 2HE HIS+ 151-1.479-8.274 6.036 1.00 0.00 ATOM 529 C HIS+ 151-3.425-5.831 2.113 1.00 0.00 ATOM 530 O HIS+ 151-2.257-6.150 1.895 1.00 0.00 ATOM 531 N THR 152-4.463-6.515 1.654 1.00 0.00 ATOM 532 H THR 152-5.371-6.204 1.856 1.00 0.00 ATOM 533 CA THR 152-4.285-7.708 0.848 1.00 0.00 ATOM 534 HA THR 152-3.559-8.333 1.347 1.00 0.00 ATOM 535 CB THR 152-5.600-8.486 0.720 1.00 0.00 ATOM 536 HB THR 152-6.158-8.099-0.122 1.00 0.00 ATOM 537 QG2 THR 152-5.351-10.323 0.444 1.00 0.00 ATOM 538 OG1 THR 152-6.389-8.341 1.889 1.00 0.00 ATOM 539 1HG THR 152-6.478-7.408 2.106 1.00 0.00 ATOM 540 CG2 THR 152-5.399-9.969 0.498 1.00 0.00 ATOM 541 1HG2 THR 152-4.601-10.324 1.133 1.00 0.00 ATOM 542 2HG2 THR 152-5.141-10.147-0.537 1.00 0.00

ATOM 543 3HG2 THR 152-6.310-10.497 0.737 1.00 0.00 ATOM 544 C THR 152-3.735-7. 354-0.525 1.00 0.00 ATOM 545 O THR 152-2.734-7.915-0.930 1.00 0.00 ATOM 546 N VAL 153-4. 370-6.408-1.222 1.00 0.00 ATOM 547 H VAL 153-5.160-5.968-0.833 1.00 0.00 ATOM 548 CA VAL 153-3.901-5.997-2.548 1.00 0.00 ATOM 549 HA VAL 153-3.958-6.856-3.198 1.00 0.00 ATOM 550 CB VAL 153-4.783-4.872-3.141 1.00 0.00 ATOM 551 HB VAL 153-4.683-3.996-2.516 1.00 0.00 ATOM 552 QG1 VAL 153-4.228-4.420-4.882 1.00 0.00 ATOM 553 QG2 VAL 153-6. 592-5.389-3.148 1.00 0.00 ATOM 554 CG1 VAL 153-4.334-4.506-4.548 1.00 0.00 ATOM 555 1HG1 VAL 153-4.367-3.433-4.670 1.00 0.00 ATOM 556 2HG1 VAL 153-4.992-4.971-5.268 1.00 0.00 ATOM 557 3HG1 VAL 153-3.324-4.856-4.706 1.00 0.00 ATOM 558 CG2 VAL 153-6.246-5.289-3.146 1.00 0.00 ATOM 559 1HG2 VAL 153-6.648-5.207-2.147 1.00 0.00 ATOM 560 2HG2 VAL 153-6.325-6.313-3.483 1.00 0.00 ATOM 561 3HG2 VAL 153-6. 801-4.646-3.813 1.00 0. 00 ATOM 562 QQG VAL 153-5.410-4.904-4.015 1.00 0.00 ATOM 563 C VAL 153-2.452-5.536-2.486 1.00 0.00 ATOM 564 O VAL 153-1.631-5.893-3.334 1.00 0.00 ATOM 565 N ALA 154-2.144-4.757-1.466 1.00 0.00 ATOM 566 H ALA 154-2.849-4.519-0.818 1.00 0.00 ATOM 567 CA ALA 154-0.796-4.254-1.263 1.00 0.00 ATOM 568 HA ALA 154-0.492-3.722-2.152 1.00 0.00 ATOM 569 QB ALA 154-0.780-3.059 0.182 1.00 0.00 ATOM 570 CB ALA 154-0.783-3.289-0.094 1.00 0.00 ATOM 571 1HB ALA 154-0.187-2.424-0.350 1.00 0.00 ATOM 572 2HB ALA 154-0.358-3.776 0.770 1.00 0.00 ATOM 573 3HB ALA 154-1.794-2.977 0.128 1.00 0.00 ATOM 574 C ALA 154 0.179-5.393-1.006 1.00 0.00 ATOM 575 O ALA 154 1.220-5.495-1.661 1.00 0.00 ATOM 576 N LYS+ 155-0.160-6.249-0.047 1.00 0.00 ATOM 577 H LYS+ 155-1.003-6.115 0.440 1.00 0.00 ATOM 578 CA LYS+ 155 0.690-7.379 0.296 1.00 0.00 ATOM 579 HA LYS+ 155 1.674-6.992 0.529 1.00 0.00 ATOM 580 CB LYS+ 155 0.145-8.131 1.515 1.00 0.00 ATOM 581 1HB LYS+ 155-0.530-8.902 1.171 1.00 0.00 ATOM 582 2HB LYS+ 155-0.403-7.437 2.136 1.00 0.00 ATOM 583 QB LYS+ 155-0.467-8.169 1.653 1.00 0.00 ATOM 584 CG LYS+ 155 1.228-8.788 2.364 1.00 0.00 ATOM 585 1HG LYS+ 155 2.040-8.088 2.495 1.00 0.00 ATOM 586 2HG LYS+ 155 1.589-9.668 1.849 1.00 0.00 ATOM 587 QG LYS+ 155 1.814-8.878 2.172 1.00 0.00 ATOM 588 CD LYS+ 155 0.700-9.199 3.731 1.00 0. 00 ATOM 589 1HD LYS+ 155 0.806-10.270 3.840 1.00 0.00 ATOM 590 2HD LYS+ 155-0.345-8.933 3.795 1.00 0.00 ATOM 591 QD LYS+ 155 0.230-9.601 3.817 1.00 0.00 ATOM 592 CE LYS+ 155 1.455-8.507 4.860 1.00 0.00 ATOM 593 1HE LYS+ 155 0.919-8.668 5.785 1.00 0.00 ATOM 594 2HE LYS+ 155 1.496-7.447 4.651 1.00 0.00 ATOM 595 QE LYS+ 155 1.207-8.057 5.218 1.00 0.00 ATOM 596 NZ LYS+ 155 2.846-9.024 5.009 1.00 0.00 ATOM 597 1HZ LYS+ 155 3.170-9.448 4.118 1.00 0.00 ATOM 598 2HZ LYS+ 155 2.882-9.749 5.756 1.00 0.00 ATOM 599 3HZ LYS+ 155 3.495-8.244 5.271 1.00 0.00 ATOM 600 QZ LYS+ 155 3.182-9.147 5.048 1.00 0.00 ATOM 601 C LYS+ 155 0.815-8.321-0.887 1.00 0.00 ATOM 602 O LYS+ 155 1.905-8.782-1.179 1.00 0.00 ATOM 603 N GLU 156-0. 300-8. 586-1.565 1.00 0.00 ATOM 604 H GLU 156-1.148-8.173-1.275 1.00 0.00 ATOM 605 CA GLU 156-0. 307-9. 464-2.730 1.00 0.00 ATOM 606 HA GLU 156-0.022-10.453-2.404 1.00 0.00 ATOM 607 CB GLU 156-1.702-9.527-3.361 1.00 0.00 ATOM 608 1HB GLU 156-1. 605-9. 852-4.386 1.00 0.00 ATOM 609 2HB GLU 156-2.138-8.539-3.348 1.00 0.00 ATOM 610 QB GLU 156-1.872-9.195-3.867 1.00 0.00 ATOM 611 CG GLU 156-2. 659-10. 472-2.652 1.00 0.00 ATOM 612 1HG GLU 156-2. 504-10. 391-1.587 1.00 0.00 ATOM 613 2HG GLU 156-2. 452-11. 482-2.970 1.00 0.00 ATOM 614 QG GLU 156-2.478-10.936-2.279 1. 00 0.00

ATOM 615 CD GLU 156-4.111-10.159-2.955 1.00 0.00 ATOM 616 OE1 GLU 156-4.389-9.049-3.458 1.00 0.00 ATOM 617 OE2 GLU 156-4. 972-11. 019-2.683 1.00 0.00 ATOM 618 C GLU 156 0.697-8.982-3.769 1.00 0.00 ATOM 619 O GLU 156 1.537-9.747-4.213 1.00 0.00 ATOM 620 N THR 157 0.603-7.707-4.141 1.00 0.00 ATOM 621 H THR 157-0.097-7.144-3.741 1.00 0.00 ATOM 622 CA THR 157 1.512-7.122-5.130 1.00 0.00 ATOM 623 HA THR 157 1.326-7.616-6.073 1.00 0.00 ATOM 624 CB THR 157 1.224-5.624-5.289 1.00 0.00 ATOM 625 HB THR 157 1.507-5.115-4.378 1.00 0.00 ATOM 626 QG2 THR 157 2.158-4.826-6.705 1.00 0.00 ATOM 627 OG1 THR 157-0.157-5.393-5.517 1.00 0.00 ATOM 628 1HG THR 157-0.669-5.692-4.752 1.00 0.00 ATOM 629 CG2 THR 157 1.979-4.979-6.432 1.00 0.00 ATOM 630 1HG2 THR 157 1.293-4.408-7.040 1.00 0. 00 ATOM 631 2HG2 THR 157 2.442-5.747-7.036 1.00 0.00 ATOM 632 3HG2 THR 157 2.741-4.324-6.037 1.00 0.00 ATOM 633 C THR 157 2.984-7.342-4.750 1.00 0.00 ATOM 634 O THR 157 3.814-7.668-5.598 1.00 0.00 ATOM 635 N CYS 158 3.307-7.155-3.478 1.00 0.00 ATOM 636 H CYS 158 2.609-6.883-2.839 1.00 0.00 ATOM 637 CA CYS 158 4.681-7.334-3.013 1.00 0.00 ATOM 638 HA CYS 158 5.339-6.912-3.759 1.00 0.00 ATOM 639 CB CYS 158 4.889-6. 581-1.699 1.00 0.00 ATOM 640 1HB CYS 158 5.752-6.981-1.196 1.00 0.00 ATOM 641 2HB CYS 158 4.020-6.724-1.076 1.00 0.00 ATOM 642 QB CYS 158 4.886-6.852-1.136 1.00 0.00 ATOM 643 SG CYS 158 5.135-4.780-1.908 1.00 0.00 ATOM 644 C CYS 158 5.036-8.816-2.844 1.00 0.00 ATOM 645 O CYS 158 6.081-9.264-3.313 1.00 0.00 ATOM 646 N SER 159 4.171-9.566-2.165 1.00 0.00 ATOM 647 H SER 159 3.361-9.149-1.804 1.00 0.00 ATOM 648 CA SER 159 4.394-10.991-1.918 1.00 0.00 ATOM 649 HA SER 159 5.378-11.088-1.485 1.00 0.00 ATOM 650 CB SER 159 3.371-11.521-0.913 1.00 0.00 ATOM 651 1HB SER 159 3.373-12.602-0.938 1.00 0.00 ATOM 652 2HB SER 159 2.388-11.155-1.176 1.00 0.00 ATOM 653 QB SER 159 2.880-11.878-1.057 1.00 0.00 ATOM 654 OG SER 159 3.687-11.090 0.407 1.00 0.00 ATOM 655 HG SER 159 4.556-11.426 0.647 1.00 0.00 ATOM 656 C SER 159 4.359-11.825-3.203 1.00 0.00 ATOM 657 O SER 159 4.930-12.912-3.241 1.00 0.00 ATOM 658 N GLU 160 3.713-11.314-4.255 1.00 0.00 ATOM 659 H GLU 160 3.281-10.435-4.179 1.00 0.00 ATOM 660 CA GLU 160 3.658-12.029-5.531 1.00 0.00 ATOM 661 HA GLU 160 3.338-13.042-5.339 1.00 0.00 ATOM 662 CB GLU 160 2.682-11.352-6.500 1.00 0. 00 ATOM 663 1HB GLU 160 3.220-10.617-7.081 1.00 0.00 ATOM 664 2HB GLU 160 1.913-10.851-5.929 1.00 0.00 ATOM 665 QB GLU 160 2.566-10.734-6.505 1.00 0.00 ATOM 666 CG GLU 160 2.006-12.313-7.465 1.00 0.00 ATOM 667 1HG GLU 160 1.278-12.897-6.922 1.00 0.00 ATOM 668 2HG GLU 160 2.755-12.970-7.882 1.00 0.00 ATOM 669 QG GLU 160 2.016-12.933-7.402 1.00 0.00 ATOM 670 CD GLU 160 1.305-11. 599-8.601 1.00 0.00 ATOM 671 OE1 GLU 160 1.796-10.533-9.025 1.00 0.00 ATOM 672 OE2 GLU 160 0.264-12.108-9.067 1.00 0.00 ATOM 673 C GLU 160 5.061-12.051-6.123 1.00 0.00 ATOM 674 0GLU 160 5.450-12.969-6.846 1.00 0.00 ATOM 675 N LYS+ 161 5.822-11.031-5.756 1.00 0.00 ATOM 676 H LYS+ 161 5.446-10.362-5.149 1.00 0.00 ATOM 677 CA LYS+ 161 7.199-10.893-6.170 1.00 0.00 ATOM 678 HA LYS+ 161 7.337-11.452-7.084 1.00 0.00 ATOM 679 CB LYS+ 161 7.538-9.415-6.407 1.00 0.00 ATOM 680 1HB LYS+ 161 7.896-8. 991-5.480 1.00 0.00 ATOM 681 2HB LYS+ 161 6.638-8. 898-6.702 1.00 0.00 ATOM 682 QB LYS+ 161 7.267-8.944-6.091 1.00 0.00 ATOM 683 CG LYS+ 161 8.597-9. 189-7.478 1.00 0.00 ATOM 684 1HG LYS+ 161 8.104-9. 052-8.431 1.00 0.00 ATOM 685 2HG LYS+ 161 9.239-10. 057-7.525 1.00 0.00 ATOM 686 QG LYS+ 161 8.671-9. 554-7. 978 1.00 0.00

ATOM 687 CD LYS+ 161 9.444-7.961-7.178 1.00 0.00 ATOM 688 1HD LYS+ 161 9.233-7.627-6.174 1.00 0.00 ATOM 689 2HD LYS+ 161 9.187-7.181-7.881 1.00 0. 00 ATOM 690 QD LYS+ 161 9.210-7.404-7.028 1.00 0.00 ATOM 691 CE LYS+ 161 10.933-8.262-7.302 1.00 0.00 ATOM 692 1HE LYS+ 161 11.443-7.364-7.619 1.00 0.00 ATOM 693 2HE LYS+ 161 11.070-9.033-8.047 1.00 0.00 ATOM 694 QE LYS+ 161 11.256-8.198-7.833 1.00 0.00 ATOM 695 NZ LYS+ 161 11.522-8.726-6.012 1. 00 0.00 ATOM 696 1HZ LYS+ 161 11.461-9.774-5.941 1.00 0.00 ATOM 697 2HZ LYS+ 161 11.014-8.309-5.208 1.00 0.00 ATOM 698 3HZ LYS+ 161 12.523-8.451-5.954 1.00 0.00 ATOM 699 QZ LYS+ 161 11.666-8.845-5.701 1.00 0.00 ATOM 700 C LYS+ 161 8.088-11.475-5.080 1.00 0.00 ATOM 701 O LYS+ 161 7.791-12.523-4.516 1.00 0.00 ATOM 702 N SER 162 9.169-10.788-4.771 1.00 0.00 ATOM 703 H SER 162 9.354-9.956-5.238 1.00 0.00 ATOM 704 CA SER 162 10.071-11.243-3.736 1.00 0.00 ATOM 705 HA SER 162 9.662-12.156-3.328 1.00 0.00 ATOM 706 CB SER 162 11.455-11.539-4.318 1.00 0.00 ATOM 707 1HB SER 162 11.735-12.554-4.071 1.00 0.00 ATOM 708 2HB SER 162 12.175-10.857-3.887 1.00 0.00 ATOM 709 QB SER 162 11.955-11.705-3.979 1.00 0.00 ATOM 710 OG SER 162 11.460-11.389-5.735 1.00 0.00 ATOM 711 HG SER 162 11.427-12.264-6.144 1.00 0.00 ATOM 712 C SER 162 10.174-10.215-2.614 1.00 0.00 ATOM 713 O SER 162 11.271-9.819-2.234 1.00 0.00 ATOM 714 N THR 163 9.032-9.774-2.088 1.00 0.00 ATOM 715 H THR 163 8.175-10.112-2.433 1.00 0.00 ATOM 716 CA THR 163 9.029-8.803-0.996 1.00 0.00 ATOM 717 HA THR 163 9.950-8.939-0.441 1.00 0.00 ATOM 718 CB THR 163 8.978-7.356-1.502 1.00 0.00 ATOM 719 HB THR 163 8.858-6.710-0.638 1.00 0.00 ATOM 720 QG2 THR 163 10.522-6.806-2.410 1.00 0.00 ATOM 721 OG1 THR 163 7.884-7.153-2.375 1.00 0.00 ATOM 722 1HG THR 163 7.701-6.211-2.450 1.00 0.00 ATOM 723 CG2 THR 163 10.225-6.910-2.236 1.00 0.00 ATOM 724 1HG2 THR 163 10.696-6.105-1.691 1.00 0.00 ATOM 725 2HG2 THR 163 9.959-6.570-3.225 1.00 0.00 ATOM 726 3HG2 THR 163 10.912-7.742-2.312 1.00 0.00 ATOM 727 C THR 163 7.864-9.061-0.042 1.00 0.00 ATOM 728 O THR 163 6.872-9.692-0.399 1.00 0.00 ATOM 729 N ASN 164 7.998-8.573 1.181 1.00 0.00 ATOM 730 H ASN 164 8.824-8.088 1.410 1.00 0.00 ATOM 731 CA ASN 164 6.965-8.755 2.208 1.00 0.00 ATOM 732 HA ASN 164 6.112-9.230 1.737 1.00 0.00 ATOM 733 CB ASN 164 7.488-9.657 3.334 1.00 0.00 ATOM 734 1HB ASN 164 7.256-10.686 3.101 1.00 0.00 ATOM 735 2HB ASN 164 7.006-9.385 4.261 1.00 0.00 ATOM 736 QB ASN 164 7.131-10.035 3.681 1.00 0.00 ATOM 737 CG ASN 164 8.991-9.538 3.525 1.00 0. 00 ATOM 738 OD1 ASN 164 9.673-10.526 3.762 1.00 0. 00 ATOM 739 ND2 ASN 164 9.506-8.317 3.442 1.00 0.00 ATOM 740 1HD2 ASN 164 8.893-7.569 3.285 1.00 0. 00 ATOM 741 2HD2 ASN 164 10.476-8.221 3.484 1.00 0.00 ATOM 742 QD2 ASN 164 9.684-7.895 3.384 1.00 0.00 ATOM 743 C ASN 164 6.531-7.417 2.800 1.00 0.00 ATOM 744 O ASN 164 7.369-6.598 3.170 1.00 0.00 ATOM 745 N LEU 165 5.220-7.198 2.888 1.00 0.00 ATOM 746 H LEU 165 4.602-7.888 2.575 1.00 0.00 ATOM 747 CA LEU 165 4.680-5.949 3.440 1.00 0.00 ATOM 748 HA LEU 165 5.188-5.121 2.965 1.00 0.00 ATOM 749 CB LEU 165 3.180-5.836 3.165 1.00 0.00 ATOM 750 1HB LEU 165 2.661-5.725 4.109 1.00 0.00 ATOM 751 2HB LEU 165 2.848-6.749 2.695 1.00 0.00 ATOM 752 QB LEU 165 2.754-6.237 3.402 1.00 0.00 ATOM 753 CG LEU 165 2.776-4.672 2.284 1.00 0.00 ATOM 754 HG LEU 165 3.311-3.786 2.594 1.00 0.00 ATOM 755 QD1 LEU 165 3.220-5.030 0.500 1.00 0.00 ATOM 756 QD2 LEU 165 0.936-4.338 2.464 1.00 0.00 ATOM 757 CD1 LEU 165 3.136-4.962 0.844 1.00 0.00 ATOM 758 1HD1 LEU 165 3.913-4.284 0.523 1.00 0.00

ATOM 759 2HD1 LEU 165 2.262-4.827 0.221 1.00 0.00 ATOM 760 3HD1 LEU 165 3.485-5.979 0.757 1.00 0.00 ATOM 761 CD2 LEU 165 1.290-4.403 2.431 1.00 0.00 ATOM 762 1HD2 LEU 165 1.021-3.542 1.836 1.00 0.00 ATOM 763 2HD2 LEU 165 1.057-4.210 3.468 1.00 0.00 ATOM 764 3HD2 LEU 165 0.731-5.263 2.090 1.00 0.00 ATOM 765 QQD LEU 165 2.078-4.684 1.482 1.00 0.00 ATOM 766 C LEU 165 4.906-5. 856 4.934 1.00 0.00 ATOM 767 O LEU 165 4.480-6.736 5.689 1.00 0.00 ATOM 768 N HIS+ 166 5.554-4.779 5.343 1.00 0.00 ATOM 769 H HIS+ 166 5.850-4.118 4.677 1.00 0.00 ATOM 770 CA HIS+ 166 5.831-4. 528 6.743 1.00 0.00 ATOM 771 HA HIS+ 166 5.509-5.389 7.308 1.00 0. 00 ATOM 772 CB HIS+ 166 7.340-4.327 6.947 1.00 0.00 ATOM 773 1HB HIS+ 166 7.672-3.515 6.313 1.00 0.00 ATOM 774 2HB HIS+ 166 7.857-5.230 6.664 1.00 O. 00 ATOM 775 QB HIS+ 166 7.764-4.372 6.488 1.00 0.00 ATOM 776 CG HIS+ 166 7.733-3.997 8.353 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.657-4.893 9.397 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.201-2.847 8.879 1.00 0.00 ATOM 779 1HD HIS+ 166 7.349-5.822 9.335 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.062-4.302 10.508 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.399-3.055 10.219 1.00 0.00 ATOM 782 2HD HIS+ 166 8.369-1.919 8.341 1.00 0.00 ATOM 783 1HE HIS+ 166 8.109-4.758 11.486 1.00 0.00 ATOM 784 2HE HIS+ 166 8.522-2.341 10.880 1.00 0.00 ATOM 785 C HIS+ 166 5.045-3.301 7.220 1.00 0.00 ATOM 786 O HIS+ 166 4.358-3.358 8.240 1.00 0.00 ATOM 787 N ASP 167 5.148-2.199 6.473 1.00 0. 00 ATOM 788 H ASP 167 5.711-2.217 5.668 1.00 0.00 ATOM 789 CA ASP 167 4.448-0.959 6.832 1.00 0.00 ATOM 790 HA ASP 167 3.927-1.137 7.761 1.00 0.00 ATOM 791 CB ASP 167 5.433 0.203 7.037 1.00 0.00 ATOM 792 1HB ASP 167 5.045 0.857 7.804 1.00 0.00 ATOM 793 2HB ASP 167 5.516 0.756 6.115 1.00 0.00 ATOM 794 QB ASP 167 5.280 0.807 6.959 1.00 0.00 ATOM 795 CG ASP 167 6.823-0.238 7.447 1.00 0.00 ATOM 796 OD1 ASP 167 7.175-0.055 8.631 1.00 0.00 ATOM 797 OD2 ASP 167 7.567-0.757 6.584 1.00 0.00 ATOM 798 C ASP 167 3.427-0.549 5.770 1.00 0.00 ATOM 799 O ASP 167 3.759 0.142 4.812 1.00 0.00 ATOM 800 N TYR 168 2.186-0.971 5.949 1.00 0.00 ATOM 801 H TYR 168 1.981-1.512 6.740 1.00 0.00 ATOM 802 CA TYR 168 1.105-0.634 5. 018 1.00 0.00 ATOM 803 HA TYR 168 1.544-0.426 4.045 1.00 0.00 ATOM 804 CB TYR 168 0.133-1.811 4.890 1.00 0.00 ATOM 805 1HB TYR 168 0.498-2.490 4.135 1.00 0.00 ATOM 806 2HB TYR 168-0.834-1.436 4.591 1.00 0.00 ATOM 807 QB TYR 168-0.168-1.963 4.363 1.00 0.00 ATOM 808 QD TYR 168-0.066-2.678 6.328 1.00 0.00 ATOM 809 QE TYR 168-0.351-3.929 8.424 1.00 0.00 ATOM 810 QR TYR 168-0.208-3.304 7.376 1.00 0.00 ATOM 811 CG TYR 168-0.046-2.590 6. 178 1.00 0.00 ATOM 812 CD1 TYR 168 0.823-3.620 6.521 1.00 0.00 ATOM 813 1HD TYR 168 1.635-3.866 5.853 1.00 0.00 ATOM 814 CE1 TYR 168 0.665-4.324 7.697 1.00 0.00 ATOM 815 1HE TYR 168 1.353-5.118 7.947 1.00 0.00 ATOM 816 CZ TYR 168-0.370-4.005 8.548 1.00 0.00 ATOM 817 CE2 TYR 168-1.245-2.990 8.233 1.00 0.00 ATOM 818 2HE TYR 168-2.055-2.740 8.901 1.00 0.00 ATOM 819 CD2 TYR 168-1.082-2.289 7.054 1.00 0.00 ATOM 820 2HD TYR 168-1.766-1.491 6.804 1.00 0.00 ATOM 821 OH TYR 168-0.533-4.707 9.717 1. 00 0.00 ATOM 822 HH TYR 168-0.109-4.232 10.439 1.00 0.00 ATOM 823 C TYR 168 0.347 0.607 5.482 1.00 0.00 ATOM 824 O TYR 168 0.206 0.848 6.681 1.00 0.00 ATOM 825 N GLY 169-0.161 1.370 4.528 1.00 0.00 ATOM 826 H GLY 169-0.033 1.116 3.589 1.00 0.00 ATOM 827 CA GLY 169-0.921 2.562 4.839 1.00 0.00 ATOM 828 1HA GLY 169-0.277 3.427 4.764 1.00 0.00 ATOM 829 2HA GLY 169-1.302 2.487 5.848 1.00 0.00 ATOM 830 QA GLY 169-0.790 2.957 5.306 1.00 0.00

ATOM 831 C GLY 169-2.071 2.719 3.879 1.00 0.00 ATOM 832 O GLY 169-2.049 2.134 2.796 1.00 0.00 ATOM 833 N MET 170-3.085 3.480 4.260 1.00 0.00 ATOM 834 H MET 170-3.056 3.916 5.138 1.00 0.00 ATOM 835 CA MET 170-4.248 3.677 3.401 1.00 0.00 ATOM 836 HA MET 170-3.932 3.526 2.373 1.00 0.00 ATOM 837 CB MET 170-5.356 2.671 3.744 1.00 0.00 ATOM 838 1HB MET 170-6. 235 2.916 3.166 1.00 0.00 ATOM 839 2HB MET 170-5.593 2.763 4.794 1.00 0.00 ATOM 840 QB MET 170-5.914 2.840 3.980 1.00 0.00 ATOM 841 CG MET 170-4.991 1.222 3.464 1.00 0.00 ATOM 842 1HG MET 170-4.343 1.190 2.599 1.00 0.00 ATOM 843 2HG MET 170-5.896 0.670 3.256 1.00 0.00 ATOM 844 QG MET 170-5.120 0.930 2.927 1.00 0.00 ATOM 845 SD MET 170-4.143 0.443 4.852 1.00 0.00 ATOM 846 QE MET 170-3.823-1. 537 4.084 1.00 0.00 ATOM 847 CE MET 170-3.876-1.205 4.212 1.00 0.00 ATOM 848 1HE MET 170-4.779-1. 786 4.329 1.00 0.00 ATOM 849 2HE MET 170-3.072-1.676 4.758 1.00 0.00 ATOM 850 3HE MET 170-3.617-1.148 3.165 1.00 0.00 ATOM 851 C MET 170-4.791 5.091 3.552 1.00 0.00 ATOM 852 O MET 170-5.287 5.462 4.616 1.00 0.00 ATOM 853 N LEU 171-4.704 5.876 2.489 1.00 0.00 ATOM 854 H LEU 171-4.301 5.524 1.664 1.00 0.00 ATOM 855 CA LEU 171-5. 199 7.249 2.526 1.00 0.00 ATOM 856 HA LEU 171-5.532 7.443 3.535 1.00 0.00 ATOM 857 CB LEU 171-4. 096 8.251 2.172 1.00 0.00 ATOM 858 1HB LEU 171-4.105 9.035 2.914 1.00 0.00 ATOM 859 2HB LEU 171-4.333 8.687 1.213 1.00 0.00 ATOM 860 QB LEU 171-4.219 8.861 2.063 1.00 0.00 ATOM 861 CG LEU 171-2.682 7.685 2.099 1.00 0.00 ATOM 862 HG LEU 171-2.627 6.780 2.687 1.00 0.00 ATOM 863 QD1 LEU 171-2.229 7.262 0.323 1.00 0.00 ATOM 864 QD2 LEU 171-1.458 8.919 2.811 1.00 0.00 ATOM 865 CD1 LEU 171-2.317 7.342 0.664 1.00 0.00 ATOM 866 1HD1 LEU 171-2.331 8.241 0.062 1.00 0.00 ATOM 867 2HD1 LEU 171-3.029 6.634 0.270 1.00 0.00 ATOM 868 3HD1 LEU 171-1.327 6.910 0.639 1.00 0.00 ATOM 869 CD2 LEU 171-1.693 8.683 2.676 1.00 0.00 ATOM 870 1HD2 LEU 171-1.261 9.265 1.874 1.00 0.00 ATOM 871 2HD2 LEU 171-0.909 8.151 3.197 1.00 0.00 ATOM 872 3HD2 LEU 171-2.202 9.340 3.364 1.00 0.00 ATOM 873 QQD LEU 171-1.843 8.090 1.567 1.00 0.00 ATOM 874 C LEU 171-6. 376 7.449 1.581 1.00 0.00 ATOM 875 O LEU 171-7.001 6.486 1.135 1.00 0.00 ATOM 876 N LEU 172-6.651 8.724 1.287 1.00 0.00 ATOM 877 H LEU 172-6.091 9.421 1.686 1.00 0.00 ATOM 878 CA LEU 172-7.737 9.139 0.394 1.00 0. 00 ATOM 879 HA LEU 172-7.914 10.189 0.573 1.00 0.00 ATOM 880 CB LEU 172-7.325 8.966-1.071 1.00 0.00 ATOM 881 1HB LEU 172-8.215 8.767-1.650 1.00 0.00 ATOM 882 2HB LEU 172-6.672 8.108-1.143 1.00 0.00 ATOM 883 QB LEU 172-7.444 8.438-1.397 1.00 0.00 ATOM 884 CG LEU 172-6. 613 10.173-1.689 1.00 0. 00 ATOM 885 HG LEU 172-6.576 10.051-2.761 1.00 0.00 ATOM 886 QD1 LEU 172-7.551 11.761-1.319 1.00 0.00 ATOM 887 QD2 LEU 172-4.846 10.299-1.058 1.00 0.00 ATOM 888 CD1 LEU 172-7.371 11.457-1.390 1.00 0.00 ATOM 889 1HD1 LEU 172-7.189 12.174-2.176 1.00 0.00 ATOM 890 2HD1 LEU 172-7.033 11.863-0.448 1.00 0.00 ATOM 891 3HD1 LEU 172-8.429 11.246-1.332 1.00 0.00 ATOM 892 CD2 LEU 172-5.186 10.275-1.178 1.00 0.00 ATOM 893 1HD2 LEU 172-5. 030 9.549-0.395 1.00 0.00 ATOM 894 2HD2 LEU 172-5.012 11.267-0.789 1.00 0.00 ATOM 895 3HD2 LEU 172-4.496 10.081-1.989 1.00 0.00 ATOM 896 QQD LEU 172-6.198 11.030-1.188 1.00 0.00 ATOM 897 C LEU 172-9.039 8.386 0.664 1.00 0. 00 ATOM 898 O LEU 172-9.515 7.638-0.185 1.00 0.00 ATOM 899 N PRO 173-9.646 8.579 1.846 1.00 0.00 ATOM 900 CD PRO 173-9.174 9.464 2.931 1.00 0.00 ATOM 901 CA PRO 173-10.896 7.908 2.186 1.00 0.00 ATOM 902 HA PRO 173-10.853 6.853 1.960 1.00 0.00

ATOM 903 CB PRO 173-11.007 8.105 3.699 1.00 0.00 ATOM 904 1HB PRO 173-10.575 7.255 4.207 1.00 0.00 ATOM 905 2HB PRO 173-12. 048 8.203 3.974 1.00 0.00 ATOM 906 QB PRO 173-11.312 7.729 4.090 1.00 0.00 ATOM 907 CG PRO 173-10. 246 9.355 3.987 1.00 0.00 ATOM 908 1HG PRO 173-9.799 9.293 4.968 1.00 0.00 ATOM 909 2HG PRO 173-10.909 10.206 3.932 1.00 0.00 ATOM 910 QG PRO 173-10.354 9.750 4.450 1.00 0.00 ATOM 911 1HD PRO 173-8.227 9.122 3.321 1.00 0.00 ATOM 912 2HD PRO 173-9.091 10.484 2.584 1.00 0.00 ATOM 913 QD PRO 173-8.659 9.803 2.952 1.00 0.00 ATOM 914 C PRO 173-12.092 8.529 1.471 1.00 0.00 ATOM 915 O PRO 173-12. 333 9.732 1.570 1.00 0.00 ATOM 916 N CYS 174-12. 842 7.708 0.751 1.00 0.00 ATOM 917 H CYS 174-12.608 6. 757 0.706 1.00 0.00 ATOM 918 CA CYS 174-14.011 8.196 0.033 1.00 0.00 ATOM 919 HA CYS 174-13. 968 9.276 0.042 1.00 0.00 ATOM 920 CB CYS 174-14.008 7.713-1.419 1.00 0.00 ATOM 921 1HB CYS 174-12. 986 7.625-1.755 1.00 0.00 ATOM 922 2HB CYS 174-14. 519 8.442-2.029 1.00 0.00 ATOM 923 QB CYS 174-13. 753 8.034-1.892 1.00 0.00 ATOM 924 SG CYS 174-14.824 6.105-1.688 1.00 0.00 ATOM 925 C CYS 174-15. 285 7.763 0.742 1.00 0.00 ATOM 926 O CYS 174-16. 356 8.326 0.522 1.00 0.00 ATOM 927 N GLY 175-15.156 6.771 1.612 1.00 0.00 ATOM 928 H GLY 175-14.272 6.371 1.760 1.00 0.00 ATOM 929 CA GLY 175-16.294 6.293 2.364 1.00 0.00 ATOM 930 1HA GLY 175-16.496 5.269 2.092 1.00 0.00 ATOM 931 2HA GLY 175-17.155 6.902 2.126 1.00 0.00 ATOM 932 QA GLY 175-16.826 6.086 2.109 1.00 0.00 ATOM 933 C GLY 175-16.025 6.368 3.848 1.00 0.00 ATOM 934 O GLY 175-14. 952 6.807 4.253 1.00 0.00 ATOM 935 N ILE 176-16. 985 5.937 4.659 1.00 0.00 ATOM 936 H ILE 176-17.817 5.593 4.277 1.00 0.00 ATOM 937 CA ILE 176-16.819 5.958 6.109 1.00 0.00 ATOM 938 HA ILE 176-16. 609 6.976 6.407 1.00 0.00 ATOM 939 CB ILE 176-18.095 5.483 6.842 1.00 0.00 ATOM 940 HB ILE 176-18.025 4. 414 6.981 1.00 0.00 ATOM 941 QG2 ILE 176-18. 219 6.283 8.539 1.00 0.00 ATOM 942 CG2 ILE 176-18.194 6.130 8.214 1.00 0.00 ATOM 943 1HG2 ILE 176-18. 704 5.461 8.891 1.00 0. 00 ATOM 944 2HG2 ILE 176-18.749 7.054 8.137 1.00 0.00 ATOM 945 3HG2 ILE 176-17. 202 6.335 8.589 1.00 0.00 ATOM 946 CG1 ILE 176-19. 347 5.800 6. 020 1. 00 0.00 ATOM 947 1HG1 ILE 176-19.084 5.851 4.975 1.00 0.00 ATOM 948 2HG1 ILE 176-19.742 6.755 6.334 1.00 0.00 ATOM 949 QG1 ILE 176-19.413 6.303 5.654 1.00 0.00 ATOM 950 QD1 ILE 176-20.707 4.528 6.215 1.00 0.00 ATOM 951 CD1 ILE 176-20. 445 4.772 6.177 1.00 0.00 ATOM 952 1HD1 ILE 176-21. 112 5.077 6.970 1.00 0.00 ATOM 953 2HD1 ILE 176-20.010 3.815 6. 422 1.00 0.00 ATOM 954 3HD1 ILE 176-20. 998 4. 692 5.253 1.00 0.00 ATOM 955 C ILE 176-15.643 5.070 6.516 1.00 0.00 ATOM 956 0 ILE 176-14. 788 5.475 7.301 1.00 0.00 ATOM 957 N ASP 177-15.607 3.865 5.952 1.00 0.00 ATOM 958 H ASP 177-16.314 3.616 5.325 1.00 0.00 ATOM 959 CA ASP 177-14. 536 2.911 6. 222 1.00 0.00 ATOM 960 HA ASP 177-13.768 3.420 6.789 1.00 0.00 ATOM 961 CB ASP 177-15. 060 1.726 7.041 1.00 0.00 ATOM 962 1HB ASP 177-15. 583 1.047 6.384 1.00 0.00 ATOM 963 2HB ASP 177-15.741 2.088 7. 795 1.00 0. 00 ATOM 964 QB ASP 177-15.662 1.568 7.089 1.00 0.00 ATOM 965 CG ASP 177-13. 948 0.960 7.732 1.00 0.00 ATOM 966 OD1 ASP 177-12. 891 1.564 8.011 1.00 0.00 ATOM 967 OD2 ASP 177-14. 132-0. 248 7.988 1.00 0.00 ATOM 968 C ASP 177-13. 936 2.415 4.907 1.00 0.00 ATOM 969 O ASP 177-13. 532 1.257 4.777 1.00 0.00 ATOM 970 N LYS+ 178-13. 886 3.301 3.920 1.00 0.00 ATOM 971 H LYS+ 178-14. 220 4. 209 4.076 1.00 0.00 ATOM 972 CA LYS+ 178-13. 338 2.955 2.614 1.00 0.00 ATOM 973 HA LYS+ 178-12. 874 1.984 2.698 1.00 0.00 ATOM 974 CB LYS+ 178-14.435 2.898 1.548 1.00 0.00

ATOM 975 1HB LYS+ 178-13.993 2.577 0.617 1.00 0.00 ATOM 976 2HB LYS+ 178-14.831 3.890 1.416 1.00 0.00 ATOM 977 QB LYS+ 178-14.412 3.234 1.016 1.00 0.00 ATOM 978 CG LYS+ 178-15.590 1.956 1.881 1.00 0.00 ATOM 979 1HG LYS+ 178-16. 336 2.031 1.103 1.00 0.00 ATOM 980 2HG LYS+ 178-16. 022 2.254 2.824 1.00 0.00 ATOM 981 QG LYS+ 178-16.179 2.143 1.963 1.00 0.00 ATOM 982 CD LYS+ 178-15.131 0.506 1.988 1.00 0.00 ATOM 983 1HD LYS+ 178-15.289 0. 165 3.002 1.00 0.00 ATOM 984 2HD LYS+ 178-14.078 0.457 1.753 1.00 0.00 ATOM 985 QD LYS+ 178-14.684 0.311 2.377 1.00 0.00 ATOM 986 CE LYS+ 178-15.894-0.403 1.031 1.00 0.00 ATOM 987 1HE LYS+ 178-15. 675-0.098 0.016 1.00 0.00 ATOM 988 2HE LYS+ 178-16.952-0.293 1.216 1.00 0.00 ATOM 989 QE LYS+ 178-16.314-0.195 0.616 1.00 0.00 ATOM 990 NZ LYS+ 178-15.521-1.838 1.195 1.00 0.00 ATOM 991 1HZ LYS+ 178-16.351-2.397 1.466 1.00 0.00 ATOM 992 2HZ LYS+ 178-14.789-1.946 1.929 1.00 0.00 ATOM 993 3HZ LYS+ 178-15.146-2.220 0.287 1.00 0.00 ATOM 994 QZ LYS+ 178-15.429-2.188 1.227 1.00 0.00 ATOM 995 C LYS+ 178-12.274 3.954 2.205 1.00 0.00 ATOM 996 O LYS+ 178-12.437 5.162 2.375 1.00 0.00 ATOM 997 N PHE 179-11.186 3.436 1.669 1.00 0.00 ATOM 998 H PHE 179-11. 129 2.464 1.560 1.00 0. 00 ATOM 999 CA PHE 179-10.070 4.263 1.241 1.00 0.00 ATOM 1000 HA PHE 179-10.313 5.292 1.452 1.00 0.00 ATOM 1001 CB PHE 179-8.803 3.881 2.000 1.00 0.00 ATOM 1002 1HB PHE 179-8.088 4.668 1.885 1.00 0.00 ATOM 1003 2HB PHE 179-8.395 2.980 1.573 1.00 0.00 ATOM 1004 QB PHE 179-8.242 3.824 1.729 1.00 0.00 ATOM 1005 QD PHE 179-9.038 3.626 3.632 1.00 0.00 ATOM 1006 QE PHE 179-9.400 3.258 6.037 1.00 0. 00 ATOM 1007 QR PHE 179-9.292 3.368 5.316 1.00 0.00 ATOM 1008 CG PHE 179-9.015 3.651 3.470 1.00 0.00 ATOM 1009 CD1 PHE 179-9.316 2.388 3.953 1.00 0.00 ATOM 1010 1HD PHE 179-9.393 1.560 3.263 1.00 0.00 ATOM 1011 CE1 PHE 179-9.519 2.179 5.303 1.00 0.00 ATOM 1012 1HE PHE 179-9.756 1.190 5.667 1.00 0.00 ATOM 1013 CZ PHE. 179-9.421 3.235 6.186 1.00 0.00 ATOM 1014 HZ PHE 179-9.583 3.074 7.242 1.00 0.00 ATOM 1015 CE2 PHE 179-9.120 4.498 5.717 1.00 0.00 ATOM 1016 2HE PHE 179-9.044 5.326 6.407 1.00 0.00 ATOM 1017 CD2 PHE 179-8. 919 4.702 4.366 1.00 0.00 ATOM 1018 2HD PHE 179-8.683 5.691 4.001 1.00 0.00 ATOM 1019 C PHE 179-9.810 4. 105-0.240 1.00 0.00 ATOM 1020 O PHE 179-10.400 3.253-0. 896 1.00 0.00 ATOM 1021 N ARG+ 180-8.898 4.912-0.752 1.00 0.00 ATOM 1022 H ARG+ 180-8.449 5.557-0. 163 1.00 0.00 ATOM 1023 CA ARG+ 180-8.524 4.856-2. 155 1.00 0.00 ATOM 1024 HA ARG+ 180-8.932 3.947-2. 574 1.00 0.00 ATOM 1025 CB ARG+ 180-9.090 6.059-2.919 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.845 5.948-3.965 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.623 6.959-2.546 1.00 0.00 ATOM 1028 QB ARG+ 180-8.734 6.454-3. 256 1.00 0.00 ATOM 1029 CG ARG+ 180-10.597 6.217-2.795 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.824 6.624-1.819 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.059 5.245-2. 898 1.00 0.00 ATOM 1032 QG ARG+ 180-10.942 5.935-2.359 1.00 0.00 ATOM 1033 CD ARG+ 180-11.152 7.146-3. 862 1.00 0.00 ATOM 1034 1HD ARG+ 180-10.333 7.705-4.294 1.00 0.00 ATOM 1035 2HD ARG+ 180-11.846 7.830-3. 397 1.00 0.00 ATOM 1036 QD ARG+ 180-11.090 7.768-3.846 1.00 0.00 ATOM 1037 NE ARG+ 180-11.843 6.415-4. 925 1.00 0.00 ATOM 1038 HE ARG+ 180-11.706 5.440-4. 967 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.629 6.999-5.833 1.00 0.00 ATOM 1040 NH1 ARG+ 180-12.804 8.315-5. 805 1.00 0. 00 ATOM 1041 1HH1 ARG+ 180-12.348 8.866-5.105 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13. 383 8. 760-6.490 1.00 0.00 ATOM 1043 QH1 ARG+ 180-12.866 8.813-5. 798 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.221 6.272-6.774 1.00 0. 00 ATOM 1045 1HH2 ARG+ 180-13.082 5.276-6.810 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.798 6.713-7.463 1.00 0.00

ATOM 1047 QH2 ARG+ 180-13. 440 5.995-7.137 1.00 0.00 ATOM 1048 C ARG+ 180-7.007 4.831-2.299 1.00 0.00 ATOM 1049 O ARG+ 180-6.480 4.446-3.333 1.00 0.00 ATOM 1050 N GLY 181-6.303 5.247-1.258 1.00 0.00 ATOM 1051 H GLY 181-6.767 5.543-0.443 1.00 0.00 ATOM 1052 CA GLY 181-4.856 5.271-1.319 1.00 0.00 ATOM 1053 1HA GLY 181-4.508 6.230-0.964 1.00 0.00 ATOM 1054 2HA GLY 181-4. 551 5.151-2.348 1.00 0.00 ATOM 1055 QA GLY 181-4.530 5.691-1.656 1.00 0.00 ATOM 1056 C GLY 181-4.212 4.184-0.494 1.00 0.00 ATOM 1057 O GLY 181-4.786 3.723 0.491 1.00 0.00 ATOM 1058 N VAL 182-3.014 3.778-0.896 1.00 0.00 ATOM 1059 H VAL 182-2.613 4.194-1.686 1.00 0.00 ATOM 1060 CA VAL 182-2.267 2.741-0.194 1.00 0.00 ATOM 1061 HA VAL 182-2.627 2.701 0.827 1.00 0.00 ATOM 1062 CB VAL 182-2. 442 1.341-0.840 1.00 0.00 ATOM 1063 HB VAL 182-1.632 1.195-1.541 1.00 0.00 ATOM 1064 QG1 VAL 182-2.329-0.008 0.464 1.00 0.00 ATOM 1065 QG2 VAL 182-4.066 1.201-1.784 1.00 0.00 ATOM 1066 CG1 VAL 182-2.350 0.250 0.215 1.00 0.00 ATOM 1067 1HG1 VAL 182-3.228-0.377 0.160 1.00 0.00 ATOM 1068 2HG1 VAL 182-2.290 0.701 1.195 1.00 0.00 ATOM 1069 3HG1 VAL 182-1.468-0.348 0.037 1.00 0.00 ATOM 1070 CG2 VAL 182-3.755 1.228-1.603 1.00 0.00 ATOM 1071 1HG2 VAL 182-4.536 1.734-1.054 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.015 0.186-1.720 1.00 0.00 ATOM 1073 3HG2 VAL 182-3. 646 1.683-2.576 1.00 0.00 ATOM 1074 QQG VAL 182-3.197 0.597-0.660 1.00 0.00 ATOM 1075 C VAL 182-0.780 3.087-0.176 1.00 0.00 ATOM 1076 O VAL 182-0.205 3.441-1.203 1.00 0.00 ATOM 1077 N GLU 183-0. 172 2.982 0.997 1.00 0.00 ATOM 1078 H GLU 183-0.695 2.697 1.777 1.00 0. 00 ATOM 1079 CA GLU 183 1.246 3.280 1.177 1.00 0.00 ATOM 1080 HA GLU 183 1.696 3.402 0.200 1.00 0.00 ATOM 1081 CB GLU 183 1.414 4.570 1.986 1.00 0.00 ATOM 1082 1HB GLU 183 1.968 5.283 1.393 1.00 0.00 ATOM 1083 2HB GLU 183 1.978 4.346 2.880 1.00 0.00 ATOM 1084 QB GLU 183 1.973 4.815 2.136 1.00 0.00 ATOM 1085 CG GLU 183 0.103 5.218 2.408 1.00 0.00 ATOM 1086 1HG GLU 183-0.645 4.448 2.524 1.00 0.00 ATOM 1087 2HG GLU 183-0. 209 5.906 1.636 1.00 0.00 ATOM 1088 QG GLU 183-0.427 5.177 2.080 1.00 0.00 ATOM 1089 CD GLU 183 0.219 5.980 3.711 1.00 0.00 ATOM 1090 OE1 GLU 183 0.956 6.988 3.747 1.00 0.00 ATOM 1091 OE2 GLU 183-0.435 5.578 4.691 1.00 0.00 ATOM 1092 C GLU 183 1.924 2.132 1.918 1.00 0.00 ATOM 1093 O GLU 183 1.995 2.138 3.140 1.00 0.00 ATOM 1094 N PHE 184 2.391 1.132 1.194 1.00 0.00 ATOM 1095 H PHE 184 2.295 1.154 0.223 1.00 0.00 ATOM 1096 CA PHE 184 3.011-0.023 1.832 1.00 0.00 ATOM 1097 HA PHE 184 2.878 0.095 2.895 1.00 0.00 ATOM 1098 CB PHE 184 2.320-1.320 1.401 1.00 0.00 ATOM 1099 1HB PHE 184 1.424-1.457 1.990 1.00 0.00 ATOM 1100 2HB PHE 184 2.989-2.146 1.599 1.00 0.00 ATOM 1101 QB PHE 184 2.206-1.801 1.794 1.00 0.00 ATOM 1102 QD PHE 184 1.892-1.397-0.227 1.00 0.00 ATOM 1103 QE PHE 184 1.246-1.578-2.591 1.00 0.00 ATOM 1104 QR PHE 184 1.439-1.526-1.882 1.00 0.00 ATOM 1105 CG PHE 184 1.939-1.390-0.060 1.00 0.00 ATOM 1106 CD1 PHE 184 2.560-2.298-0.900 1.00 0.00 ATOM 1107 1HD PHE 184 3.338-2.933-0.507 1.00 0.00 ATOM 1108 CE1 PHE 184 2.196-2.403-2.227 1.00 0.00 ATOM 1109 1HE PHE 184 2.692-3.117-2.868 1.00 0.00 ATOM 1110 CZ PHE 184 1.205-1.593-2.737 1.00 0.00 ATOM 1111 HZ PHE 184 0.916-1.680-3.773 1.00 0.00 ATOM 1112 CE2 PHE 184 0.578-0.677-1.917 1.00 0.00 ATOM 1113 2HE PHE 184-0. 199-0. 039-2.314 1.00 0.00 ATOM 1114 CD2 PHE 184 0.939-0.581-0.586 1.00 0.00 ATOM 1115 2HD PHE 184 0.447 0.138 0.053 1.00 0.00 ATOM 1116 C PHE 184 4.498-0.140 1.549 1.00 0.00 ATOM 1117 O PHE 184 4.959 0.116 0.443 1.00 0.00 ATOM 1118 N VAL 185 5.237-0.560 2.564 1.00 0.00

ATOM 1119 H VAL 185 4.800-0.762 3.420 1.00 0.00 ATOM 1120 CA VAL 185 6.669-0.749 2.449 1.00 0.00 ATOM 1121 HA VAL 185 6.976-0.408 1.469 1.00 0.00 ATOM 1122 CB VAL 185 7.436 0.061 3.522 1.00 0.00 ATOM 1123 HB VAL 185 7.605-0.580 4.381 1.00 0.00 ATOM 1124 QG1 VAL 185 9.102 0.623 2.871 1.00 0.00 ATOM 1125 QG2 VAL 185 6.439 1.550 4.095 1.00 0.00 ATOM 1126 CG1 VAL 185 8.784 0.514 2.995 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.544 0.309 3.734 1.00 0.00 ATOM 1128 2HG1 VAL 185 8.751 1.576 2.798 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.012-0.016 2.083 1.00 0.00 ATOM 1130 CG2 VAL 185 6.630 1.265 3.984 1.00 0.00 ATOM 1131 1HG2 VAL 185 6.760 2.078 3.285 1. 00 0.00 ATOM 1132 2HG2 VAL 185 6.973 1.572 4.962 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.584 0.999 4.039 1.00 0.00 ATOM 1134 QQG VAL 185 7.770 1.086 3.483 1.00 0.00 ATOM 1135 C VAL 185 6.996-2.239 2.585 1.00 0.00 ATOM 1136 O VAL 185 6.772-2. 842 3.634 1.00 0.00 ATOM 1137 N CYS 186 7.498-2. 841 1.515 1.00 0.00 ATOM 1138 H CYS 186 7.638-2. 321 0.691 1.00 0.00 ATOM 1139 CA CYS 186 7.827-4. 264 1.530 1.00 0.00 ATOM 1140 HA CYS 186 7.616-4. 636 2.524 1.00 0.00 ATOM 1141 CB CYS 186 6.954-5.028 0.524 1.00 0.00 ATOM 1142 1HB CYS 186 5.927-4. 994 0.859 1.00 0.00 ATOM 1143 2HB CYS 186 7.278-6.057 0.493 1.00 0.00 ATOM 1144 QB CYS 186 6.602-5.525 0.676 1.00 0.00 ATOM 1145 SG CYS 186 6.999-4.395-1.184 1.00 0.00 ATOM 1146 C CYS 186 9.308-4.483 1.237 1.00 0.00 ATOM 1147 O CYS 186 9.833-3.958 0.266 1.00 0. 00 ATOM 1148 N CYS 187 9.986-5.260 2.075 1.00 0.00 ATOM 1149 H CYS 187 9.523-5.665 2.839 1.00 0.00 ATOM 1150 CA CYS 187 11.416-5.514 1.875 1.00 0.00 ATOM 1151 HA CYS 187 11.821-4.674 1.333 1.00 0.00 ATOM 1152 CB CYS 187 12.155-5.636 3.212 1.00 0.00 ATOM 1153 1HB CYS 187 12.958-6.352 3.105 1.00 0.00 ATOM 1154 2HB CYS 187 11.467-5.986 3.967 1.00 0.00 ATOM 1155 QB CYS 187 12.212-6.169 3.536 1.00 0.00 ATOM 1156 SG CYS 187 12.879-4.073 3.802 1.00 0.00 ATOM 1157 C CYS 187 11.648-6.766 1.055 1.00 0.00 ATOM 1158 O CYS 187 10.810-7.662 1.040 1.00 0.00 ATOM 1159 N PRO 188 12.791-6.832 0.350 1.00 0.00 ATOM 1160 CD PRO 188 13.835-5.784 0.316 1.00 0.00 ATOM 1161 CA PRO 188 13.130-7.980-0.491 1.00 0.00 ATOM 1162 HA PRO 188 12.338-8.196-1.193 1.00 0.00 ATOM 1163 CB PRO 188 14.376-7.522-1.257 1.00 0.00 ATOM 1164 1HB PRO 188 14.089-7.170-2.235 1.00 0.00 ATOM 1165 2HB PRO 188 15.060-8.353-1.356 1.00 0.00 ATOM 1166 QB PRO 188 14.574-7.761-1.796 1.00 0.00 ATOM 1167 CG PRO 188 14.969-6.426-0.436 1.00 0.00 ATOM 1168 1HG PRO 188 15.447-5.703-1.082 1.00 0.00 ATOM 1169 2HG PRO 188 15.688-6.840 0.257 1.00 0.00 ATOM 1170 QG PRO 188 15.567-6.271-0.413 1.00 0.00 ATOM 1171 1HD PRO 188 13.484-4.902-0.203 1.00 0.00 ATOM 1172 2HD PRO 188 14.151-5.527 1.317 1.00 0.00 ATOM 1173 QD PRO 188 13.817-5.214 0.557 1.00 0.00 ATOM 1174 C PRO 188 13.427-9.239 0.319 1.00 0.00 ATOM 1175 O PRO 188 14.269-9.228 1.220 1.00 0.00 ATOM 1176 N LEU 189 12.729-10.313-0.022 1.00 0.00 ATOM 1177 H LEU 189 12.080-10.242-0.754 1.00 0.00 ATOM 1178 CA LEU 189 12.895-11. 597 0.637 1.00 0.00 ATOM 1179 HA LEU 189 13.745-11.527 1.300 1.00 0.00 ATOM 1180 CB LEU 189 11.646-11.952 1.448 1.00 0.00 ATOM 1181 1HB LEU 189 10.858-12. 206 0.756 1.00 0.00 ATOM 1182 2HB LEU 189 11.345-11.080 2.008 1.00 0.00 ATOM 1183 QB LEU 189 11.101-11.643 1.382 1.00 0.00 ATOM 1184 CG LEU 189 11.818-13.118 2.424 1.00 0.00 ATOM 1185 HG LEU 189 12.522-13. 824 2.006 1.00 0.00 ATOM 1186 QD1 LEU 189 12.507-12. 512 4.062 1.00 0.00 ATOM 1187 QD2 LEU 189 10.183-14. 007 2.685 1.00 0.00 ATOM 1188 CD1 LEU 189 12.376-12. 628 3.750 1.00 0.00 ATOM 1189 1HD1 LEU 189 12.482-13. 463 4.425 1.00 0.00 ATOM 1190 2HD1 LEU 189 11.700-11. 902 4.177 1.00 0.00

ATOM 1191 3HD1 LEU 189 13.340-12.171 3.586 1.00 0.00 ATOM 1192 CD2 LEU 189 10.496-13.837 2.635 1.00 0.00 ATOM 1193 1HD2 LEU 189 9.981-13.926 1.691 1.00 0.00 ATOM 1194 2HD2 LEU 189 9.887-13.274 3.327 1.00 0.00 ATOM 1195 3HD2 LEU 189 10.683-14.821 3.038 1.00 0.00 ATOM 1196 QQD LEU 189 11.345-13.259 3.374 1.00 0.00 ATOM 1197 C LEU 189 13.162-12.679-0.405 1.00 0.00 ATOM 1198 OT1 LEU 189 13.750-13.720-0.046 1.00 0.00 ATOM 1199 OT2 LEU 189 12.780-12.472-1.578 1.00 0. 00 TER ENDMDL MODEL 4 ATOM 1 N SER 124 11.459 10.254 6.085 1.00 0.00 ATOM 2 CA SER 124 10.324 11.185 5.853 1.00 0.00 ATOM 3 HA SER 124 9.422 10.610 5.706 1.00 0.00 ATOM 4 CB SER 124 10.181 12.050 7.104 1.00 0.00 ATOM 5 1HB SER 124 9.142 12.092 7.397 1.00 0.00 ATOM 6 2HB SER 124 10. 538 13.049 6.890 1.00 0.00 ATOM 7 QB SER 124 9.840 12.570 7.144 1.00 0.00 ATOM 8 OG SER 124 10.943 11.507 8. 175 1.00 0.00 ATOM 9 HG SER 124 11.278 12.224 8.729 1.00 0.00 ATOM 10 C SER 124 10. 575 12.059 4.630 1.00 0.00 ATOM 11 O SER 124 9.665 12.696 4.104 1.00 0.00 ATOM 12 1HT SER 124 11.754 10.306 7.083 1.00 0.00 ATOM 13 2HT SER 124 12.269 10.515 5.485 1.00 0.00 ATOM 14 3HT SER 124 11.176 9.280 5.867 1.00 0.00 ATOM 15 N ASP 125 11.826 12.086 4.208 1.00 0.00 ATOM 16 H ASP 125 12.500 11.563 4.691 1.00 0.00 ATOM 17 CA ASP 125 12.275 12.877 3.074 1.00 0.00 ATOM 18 HA ASP 125 11.666 13.766 3.016 1.00 0.00 ATOM 19 CB ASP 125 13.732 13.281 3.316 1.00 0.00 ATOM 20 1HB ASP 125 13.798 14.357 3.375 1.00 0.00 ATOM 21 2HB ASP 125 14.337 12.931 2.493 1.00 0.00 ATOM 22 QB ASP 125 14.068 13.644 2.934 1.00 0.00 ATOM 23 CG ASP 125 14.285 12.692 4.605 1.00 0.00 ATOM 24 OD1 ASP 125 14. 679 13.472 5.490 1.00 0.00 ATOM 25 OD2 ASP 125 14.285 11.443 4.745 1.00 0.00 ATOM 26 C ASP 125 12.168 12.103 1.762 1.00 0.00 ATOM 27 O ASP 125 12.869 12.405 0.797 1.00 0.00 ATOM 28 N ALA 126 11.292 11.108 1.724 1.00 0.00 ATOM 29 H ALA 126 10.755 10.911 2.516 1.00 0. 00 ATOM 30 CA ALA 126 11.111 10.305 0.523 1.00 0.00 ATOM 31 HA ALA 126 11.400 10.908-0.326 1.00 0.00 ATOM 32 QB ALA 126 12.226 8.787 0.570 1.00 0.00 ATOM 33 CB ALA 126 12.013 9.078 0.561 1.00 0.00 ATOM 34 1HB ALA 126 11.467 8.244 0.977 1.00 0.00 ATOM 35 2HB ALA 126 12.878 9.285 1.174 1.00 0.00 ATOM 36 3HB ALA 126 12.333 8.834-0.441 1.00 0.00 ATOM 37 C ALA 126 9.662 9.880 0.361 1.00 0.00 ATOM 38 O ALA 126 8.992 9.550 1.339 1.00 0.00 ATOM 39 N LEU 127 9.191 9.882-0.879 1.00 0.00 ATOM 40 H LEU 127 9.781 10.149-1.609 1.00 0.00 ATOM 41 CA LEU 127 7.822 9.488-1.184 1.00 0.00 ATOM 42 HA LEU 127 7.263 9.485-0.263 1.00 0.00 ATOM 43 CB LEU 127 7.191 10.493-2.161 1.00 0.00 ATOM 44 1HB LEU 127 7.397 10.154-3.166 1.00 0.00 ATOM 45 2HB LEU 127 7.676 11.448-2.019 1.00 0.00 ATOM 46 QB LEU 127 7.537 10.801-2.592 1.00 0.00 ATOM 47 CG LEU 127 5.673 10.704-2.032 1.00 0.00 ATOM 48 HG LEU 127 5.457 11.758-2.140 1.00 0.00 ATOM 49 QD1 LEU 127 4.758 9.789-3.397 1.00 0.00 ATOM 50 QD2 LEU 127 5.048 10.154-0.342 1.00 0.00 ATOM 51 CD1 LEU 127 4.934 9.966-3.137 1.00 0.00 ATOM 52 1HD1 LEU 127 3.880 9.926-2.900 1.00 0.00 ATOM 53 2HD1 LEU 127 5.321 8.960-3.219 1.00 0.00 ATOM 54 3HD1 LEU 127 5.073 10.483-4.074 1.00 0.00 ATOM 55 CD2 LEU 127 5.168 10.260-0.666 1.00 0.00 ATOM 56 1HD2 LEU 127 5.238 9.185-0.589 1.00 0.00 ATOM 57 2HD2 LEU 127 4.138 10.563-0.546 1.00 0.00 ATOM 58 3HD2 LEU 127 5.769 10.716 0.107 1.00 0.00 ATOM 59 QQD LEU 127 4.903 9.972-1.870 1.00 0.00 ATOM 60 C LEU 127 7.808 8.083-1.782 1.00 0.00

ATOM 61 O LEU 127 6.756 7.539-2.112 1.00 0.00 ATOM 62 N LEU 128 8.992 7.499-1.917 1.00 0. 00 ATOM 63 H LEU 128 9.795 7.977-1.632 1.00 0.00 ATOM 64 CA LEU 128 9.122 6.164-2.468 1.00 0.00 ATOM 65 HA LEU 128 8.164 5.678-2.391 1.00 0.00 ATOM 66 CB LEU 128 9.530 6.242-3.946 1.00 0.00 ATOM 67 1HB LEU 128 10.607 6.204-4.000 1.00 0.00 ATOM 68 2HB LEU 128 9.201 7.195-4.336 1.00 0.00 ATOM 69 QB LEU 128 9.904 6.699-4.168 1.00 0.00 ATOM 70 CG LEU 128 8.963 5.134-4.842 1.00 0.00 ATOM 71 HG LEU 128 8.564 4.341-4.223 1.00 0. 00 ATOM 72 QD1 LEU 128 7.555 5.803-5.892 1.00 0.00 ATOM 73 QD2 LEU 128 10.312 4.415-5.938 1.00 0.00 ATOM 74 CD1 LEU 128 7.825 5.675-5.691 1.00 0. 00 ATOM 75 1HD1 LEU 128 7.241 6.373-5.108 1.00 0.00 ATOM 76 2HD1 LEU 128 7.195 4.859-6.011 1.00 0.00 ATOM 77 3HD1 LEU 128 8.229 6.179-6.557 1.00 0.00 ATOM 78 CD2 LEU 128 10.053 4.552-5.727 1.00 0.00 ATOM 79 1HD2 LEU 128 9.729 4.575-6.758 1.00 0.00 ATOM 80 2HD2 LEU 128 10.252 3.533-5.434 1.00 0.00 ATOM 81 3HD2 LEU 128 10.955 5.139-5.622 1.00 0.00 ATOM 82 QQD LEU 128 8.934 5.109-5.915 1.00 0.00 ATOM 83 C LEU 128 10.140 5.371-1.652 1.00 0.00 ATOM 84 O LEU 128 10.290 5.613-0.456 1.00 0.00 ATOM 85 N VAL 129 10.816 4.425-2.302 1.00 0.00 ATOM 86 H VAL 129 10.627 4.293-3.252 1.00 0.00 ATOM 87 CA VAL 129 11.819 3.565-1.654 1.00 0.00 ATOM 88 HA VAL 129 11.295 2.860-1.028 1.00 0.00 ATOM 89 CB VAL 129 12.619 2.767-2.710 1.00 0. 00 ATOM 90 HB VAL 129 13.250 3.460-3.248 1.00 0.00 ATOM 91 QG1 VAL 129 13.731 1.484-1.896 1.00 0.00 ATOM 92 QG2 VAL 129 11.464 1.946-3.943 1.00 0.00 ATOM 93 CG1 VAL 129 13.517 1.730-2.053 1.00 0.00 ATOM 94 1HG1 VAL 129 13.699 0.920-2.743 1.00 0.00 ATOM 95 2HG1 VAL 129 13.037 1.344-1.165 1.00 0.00 ATOM 96 3HG1 VAL 129 14.457 2.188-1.781 1.00 0.00 ATOM 97 CG2 VAL 129 11.684 2.103-3.708 1.00 0.00 ATOM 98 1HG2 VAL 129 11.797 1.031-3.647 1.00 0.00 ATOM 99 2HG2 VAL 129 11.930 2.436-4.705 1.00 0. 00 ATOM 100 3HG2 VAL 129 10.664 2.372-3.479 1.00 0.00 ATOM 101 QQG VAL 129 12.597 1.715-2.920 1.00 0.00 ATOM 102 C VAL 129 12.806 4.356-0.786 1.00 0.00 ATOM 103 O VAL 129 13.622 5.117-1.300 1.00 0.00 ATOM 104 N PRO 130 12.730 4.179 0.550 1.00 0. 00 ATOM 105 CD PRO 130 11.781 3.313 1.244 1.00 0.00 ATOM 106 CA PRO 130 13.602 4.858 1.502 1.00 0.00 ATOM 107 HA PRO 130 13.803 5.866 1.200 1.00 0.00 ATOM 108 CB PRO 130 12.777 4.870 2.803 1.00 0.00 ATOM 109 1HB PRO 130 12.519 5.889 3.051 1.00 0. 00 ATOM 110 2HB PRO 130 13.366 4.445 3.602 1.00 0.00 ATOM 111 QB PRO 130 12.943 5.167 3.327 1.00 0.00 ATOM 112 CG PRO 130 11.547 4.048 2.536 1.00 0. 00 ATOM 113 1HG PRO 130 10.688 4.699 2.444 1.00 0.00 ATOM 114 2HG PRO 130 11.395 3.345 3.341 1.00 0.00 ATOM 115 QG PRO 130 11.042 4.022 2.893 1.00 0.00 ATOM 116 1HD PRO 130 10.860 3.224 0.687 1.00 0.00 ATOM 117 2HD PRO 130 12.209 2.338 1.431 1.00 0.00 ATOM 118 QD PRO 130 11.535 2.781 1.059 1.00 0.00 ATOM 119 C PRO 130 14.930 4.130 1.712 1.00 0.00 ATOM 120 O PRO 130 15.906 4.382 1.011 1.00 0.00 ATOM 121 N ASP 131 14.952 3.246 2.702 1.00 0.00 ATOM 122 H ASP 131 14.141 3.118 3.223 1.00 0.00 ATOM 123 CA ASP 131 16.156 2.484 3.044 1.00 0.00 ATOM 124 HA ASP 131 17.011 3.117 2.854 1.00 0.00 ATOM 125 CB ASP 131 16.128 2.126 4.537 1.00 0.00 ATOM 126 1HB ASP 131 15.295 1.467 4.727 1.00 0.00 ATOM 127 2HB ASP 131 16.004 3.030 5.113 1.00 0.00 ATOM 128 QB ASP 131 15.650 2.248 4.920 1.00 0.00 ATOM 129 CG ASP 131 17.395 1.442 5.003 1.00 0.00 ATOM 130 OD1 ASP 131 17.323 0.243 5.345 1.00 0.00 ATOM 131 OD2 ASP 131 18.452 2.100 5.022 1.00 0.00 ATOM 132 C ASP 131 16.289 1.212 2.190 1.00 0.00

ATOM 133 O ASP 131 16.677 1.274 1.025 1.00 0.00 ATOM 134 N LYS+ 132 15.967 0.058 2.774 1.00 0.00 ATOM 135 H LYS+ 132 15.675 0.066 3.711 1.00 0.00 ATOM 136 CA LYS+ 132 16.064-1.218 2.064 1.00 0.00 ATOM 137 HA LYS+ 132 16. 660-1.056 1.178 1.00 0.00 ATOM 138 CB LYS+ 132 16. 752-2.273 2.945 1.00 0.00 ATOM 139 1HB LYS+ 132 16.027-2.667 3.642 1.00 0.00 ATOM 140 2HB LYS+ 132 17.546-1.795 3.501 1.00 0.00 ATOM 141 QB LYS+ 132 16.787-2.231 3.572 1.00 0.00 ATOM 142 CG LYS+ 132 17.351-3.442 2.165 1.00 0.00 ATOM 143 1HG LYS+ 132 18.416-3.472 2.348 1.00 0.00 ATOM 144 2HG LYS+ 132 17.171-3.286 1.111 1.00 0.00 ATOM 145 QG LYS+ 132 17.794-3.379 1.730 1.00 0.00 ATOM 146 CD LYS+ 132 16.737-4.777 2.580 1.00 0.00 ATOM 147 1HD LYS+ 132 15.667-4.655 2.664 1.00 0.00 ATOM 148 2HD LYS+ 132 17.145-5.065 3.538 1.00 0.00 ATOM 149 QD LYS+ 132 16.406-4.860 3.101 1.00 0.00 ATOM 150 CE LYS+ 132 17.036-5.875 1.560 1.00 0.00 ATOM 151 1HE LYS+ 132 18.108-5.944 1.433 1.00 0.00 ATOM 152 2HE LYS+ 132 16.583-5.603 0.618 1.00 0.00 ATOM 153 QE LYS+ 132 17.346-5.774 1.026 1.00 0. 00 ATOM 154 NZ LYS+ 132 16.509-7.210 1.982 1.00 0. 00 ATOM 155 1HZ LYS+ 132 16.142-7.167 2.952 1.00 0.00 ATOM 156 2HZ LYS+ 132 17. 266-7. 924 1.945 1.00 0. 00 ATOM 157 3HZ LYS+ 132 15.735-7.519 1.343 1.00 0.00 ATOM 158 QZ LYS+ 132 16.381-7.537 2.080 1.00 0.00 ATOM 159 C LYS+ 132 14.686-1.715 1.649 1.00 0.00 ATOM 160 O LYS+ 132 14.559-2.680 0.895 1.00 0.00 ATOM 161 N CYS 133 13.654-1.060 2.145 1.00 0.00 ATOM 162 H CYS 133 13.812-0.300 2.740 1.00 0.00 ATOM 163 CA CYS 133 12.290-1.443 1.820 1.00 0.00 ATOM 164 HA CYS 133 12.293-2.485 1.542 1.00 0.00 ATOM 165 CB CYS 133 11. 371-1.245 3.027 1.00 0.00 ATOM 166 1HB CYS 133 10.383-0.985 2.673 1.00 0.00 ATOM 167 2HB CYS 133 11.750-0.432 3.622 1.00 0.00 ATOM 168 QB CYS 133 11.067-0.709 3.148 1.00 0.00 ATOM 169 SG CYS 133 11. 201-2.694 4.119 1.00 0.00 ATOM 170 C CYS 133 11.784-0.617 0.649 1.00 0.00 ATOM 171 O CYS 133 12.208 0.514 0.456 1.00 0.00 ATOM 172 N LYS+ 134 10. 866-1.177-0.118 1.00 0.00 ATOM 173 H LYS+ 134 10.547-2.079 0.095 1.00 0.00 ATOM 174 CA LYS+ 134 10.300-0.477-1.258 1.00 0.00 ATOM 175 HA LYS+ 134 11.000 0.291-1.557 1.00 0.00 ATOM 176 CB LYS+ 134 10.067-1.435-2.432 1.00 0.00 ATOM 177 1HB LYS+ 134 9.454-2.258-2.093 1.00 0.00 ATOM 178 2HB LYS+ 134 11.021-1.819-2.763 1.00 0.00 ATOM 179 QB LYS+ 134 10.238-2.039-2.428 1.00 0.00 ATOM 180 CG LYS+ 134 9.374-0.782-3.621 1.00 0.00 ATOM 181 1HG LYS+ 134 9.555 0.282-3.587 1.00 0.00 ATOM 182 2HG LYS+ 134 8.313-0.971-3.552 1.00 0.00 ATOM 183 QG LYS+ 134 8.934-0.345-3.569 1.00 0. 00 ATOM 184 CD LYS+ 134 9.887-1.330-4.944 1.00 0.00 ATOM 185 1HD LYS+ 134 9.593-2.367-5.031 1.00 0.00 ATOM 186 2HD LYS+ 134 10.965-1.260-4.957 1.00 0.00 ATOM 187 QD LYS+ 134 10.279-1.814-4.994 1.00 0.00 ATOM 188 CE LYS+ 134 9.328-0.555-6.131 1.00 0.00 ATOM 189 1HE LYS+ 134 9.088-1.256-6.919 1.00 0.00 ATOM 190 2HE LYS+ 134 10.085 0.132-6.483 1.00 0.00 ATOM 191 QE LYS+ 134 9.587-0.562-6.701 1.00 0.00 ATOM 192 NZ LYS+ 134 8.100 0.217-5.775 1.00 0.00 ATOM 193 1HZ LYS+ 134 8.316 0.916-5.036 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.361-0.426-5.420 1.00 0.00 ATOM 195 3HZ LYS+ 134 7.734 0.715-6.611 1.00 0.00 ATOM 196 QZ LYS+ 134 7.804 0.401-5.689 1.00 0.00 ATOM 197 C LYS+ 134 8.995 0.177-0.851 1.00 0.00 ATOM 198 O LYS+ 134 8.033-0. 506-0.517 1.00 0.00 ATOM 199 N PHE 135 8.967 1.497-0.875 1.00 0.00 ATOM 200 H PHE 135 9.769 1.989-1.148 1.00 0.00 ATOM 201 CA PHE 135 7.773 2. 231-0. 497 1.00 0.00 ATOM 202 HA PHE 135 7.203 1.612 0.181 1.00 0.00 ATOM 203 CB PHE 135 8.160 3.530 0.216 1.00 0.00 ATOM 204 1HB PHE 135 8.667 4.175-0.487 1.00 0.00

ATOM 205 2HB PHE 135 8.834 3.297 1.025 1.00 0.00- ATOM 206 QB PHE 135 8.751 3.736 0.269 1.00 0.00 ATOM 207 QD PHE 135 6.880 4.388 0.863 1.00 0.00 ATOM 208 QE PHE 135 5.014 5.665 1.829 1.00 0.00 ATOM 209 QR PHE 135 5.573 5.282 1.539 1.00 0.00 ATOM 210 CG PHE 135 7.007 4.301 0.797 1.00 0.00 ATOM 211 CD1 PHE 135 7.029 5.686 0.808 1.00 0.00 ATOM 212 1HD PHE 135 7.876 6.206 0.386 1.00 0.00 ATOM 213 CE1 PHE 135 5.982 6.406 1.350 1.00 0.00 ATOM 214 1HE PHE 135 6.011 7.486 1.352 1.00 0.00 ATOM 215 CZ PHE 135 4.898 5.744 1.888 1.00 0.00 ATOM 216 HZ PHE 135 4.075 6.305 2.313 1.00 0.00 ATOM 217 CE2 PHE 135 4.865 4.364 1. 883 1.00 0.00 ATOM 218 2HE PHE 135 4.017 3.844 2.305 1.00 0.00 ATOM 219 CD2 PHE 135 5.914 3.650 1.341 1.00 0.00 ATOM 220 2HD PHE 135 5.884 2.571 1.339 1.00 0.00 ATOM 221 C PHE 135 6.929 2.525-1.724 1.00 0.00 ATOM 222 O PHE 135 7.402 3.123-2.694 1.00 0.00 ATOM 223 N LEU 136 5.688 2.077-1.678 1.00 0.00 ATOM 224 H LEU 136 5.385 1.592-0.878 1.00 0.00 ATOM 225 CA LEU 136 4.760 2.265-2.773 1.00 0.00 ATOM 226 HA LEU 136 5.281 2.770-3.573 1.00 0.00 ATOM 227 CB LEU 136 4. 238 0.916-3.281 1.00 0.00 ATOM 228 1HB LEU 136 3. 442 1.109-3.986 1.00 0.00 ATOM 229 2HB LEU 136 3.824 0.378-2.440 1.00 0.00 ATOM 230 QB LEU 136 3.633 0.743-3.213 1.00 0.00 ATOM 231 CG LEU 136 5.274 0.021-3.963 1.00 0.00 ATOM 232 HG LEU 136 6.093 0.630-4.309 1.00 0.00 ATOM 233 QD1 LEU 136 5.952-1.245-2.750 1.00 0.00 ATOM 234 QD2 LEU 136 4.515-0.847-5.447 1.00 0.00 ATOM 235 CD1 LEU 136 5.823-1.002-2.984 1.00 0.00 ATOM 236 1HD1 LEU 136 6.533-0.526-2.323 1.00 0.00 ATOM 237 2HD1 LEU 136 6.311-1.797-3.528 1.00 0.00 ATOM 238 3HD1 LEU 136 5.011-1.412-2.401 1.00 0.00 ATOM 239 CD2 LEU 136 4.662-0.679-5.164 1.00 0.00 ATOM 240 1HD2 LEU 136 5.048-1.686-5.229 1.00 0.00 ATOM 241 2HD2 LEU 136 4.908-0.138-6.064 1.00 0.00 ATOM 242 3HD2 LEU 136 3.588-0.716-5.048 1.00 0.00 ATOM 243 QQD LEU 136 5.233-1.046-4.098 1.00 0.00 ATOM 244 C LEU 136 3.590 3.122-2.325 1.00 0. 00 ATOM 245 O LEU 136 2.526 2.604-1.996 1.00 0.00 ATOM 246 N HIS+ 137 3.781 4.431-2.328 1.00 0.00 ATOM 247 H HIS+ 137 4.646 4.792-2.610 1.00 0.00 ATOM 248 CA HIS+ 137 2.718 5.340-1.940 1.00 0.00 ATOM 249 HA HIS+ 137 2.039 4.800-1.291 1.00 0.00 ATOM 250 CB HIS+ 137 3.281 6.570-1.195 1.00 0.00 ATOM 251 1HB HIS+ 137 4.135 6.946-1.739 1.00 0.00 ATOM 252 2HB HIS+ 137 3.599 6.266-0.209 1.00 0. 00 ATOM 253 QB HIS+ 137 3.867 6.606-0.974 1.00 0.00 ATOM 254 CG HIS+ 137 2.301 7.708-1.030 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.700 8.028 0.170 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.818 8.602-1.932 1.00 0.00 ATOM 257 1HD HIS+ 137 1.845 7.566 1.037 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.892 9.060-0.005 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.944 9.429-1.272 1.00 0.00 ATOM 260 2HD HIS+ 137 2.075 8.651-2.981 1.00 0.00 ATOM 261 1HE HIS+ 137 0.290 9.526 0.763 1.00 0.00 ATOM 262 2HE HIS+ 137 0.274 10.014-1.716 1.00 0.00 ATOM 263 C HIS+ 137 1.979 5.771-3.196 1.00 0.00 ATOM 264 O HIS+ 137 2.537 6.476-4.042 1.00 0.00 ATOM 265 N GLN 138 0.739 5.337-3.331 1.00 0.00 ATOM 266 H GLN 138 0.347 4.766-2.632 1.00 0.00 ATOM 267 CA GLN 138-0.053 5.682-4.498 1.00 0.00 ATOM 268 HA GLN 138 0.339 6.605-4.897 1.00 0.00 ATOM 269 CB GLN 138 0.062 4.591-5.566 1.00 0.00 ATOM 270 1HB GLN 138-0.798 4.649-6.217 1.00 0.00 ATOM 271 2HB GLN 138 0.069 3.630-5.080 1.00 0.00 ATOM 272 QB GLN 138-0.364 4.139-5.648 1.00 0.00 ATOM 273 CG GLN 138 1.318 4.705-6.423 1.00 0.00 ATOM 274 1HG GLN 138 1.813 5.636-6.189 1.00 0.00 ATOM 275 2HG GLN 138 1.029 4.703-7.463 1.00 0.00 ATOM 276 QG GLN 138 1.421 5.169-6.826 1.00 0.00

ATOM 277 CD GLN 138 2.292 3.565-6.191 1.00 0.00 ATOM 278 OE1 GLN 138 2.004 2.415-6.513 1.00 0.00 ATOM 279 NE2 GLN 138 3.458 3.874-5.634 1.00 0.00 ATOM 280 1HE2 GLN 138 3.632 4.812-5.401 1.00 0.00 ATOM 281 2HE2 GLN 138 4.096 3.150-5.475 1.00 0.00 ATOM 282 QE2 GLN 138 3.864 3.981-5.438 1.00 0.00 ATOM 283 C GLN 138-1.509 5.896-4.115 1.00 0.00 ATOM 284 O GLN 138-2.097 5.108-3.370 1.00 0.00 ATOM 285 N GLU 139-2.080 6.968-4.629 1.00 0.00 ATOM 286 H GLU 139-1.555 7.552-5.212 1.00 0.00 ATOM 287 CA GLU 139-3.466 7.311-4.351 1.00 0.00 ATOM 288 HA GLU 139-3.758 6.805-3.444 1.00 0.00 ATOM 289 CB GLU 139-3.604 8.825-4.152 1.00 0.00 ATOM 290 1HB GLU 139-3.973 9.015-3.154 1.00 0.00 ATOM 291 2HB GLU 139-4.317 9.206-4.867 1.00 0.00 ATOM 292 QB GLU 139-4.145 9.110-4.010 1.00 0.00 ATOM 293 CG GLU 139-2.298 9.592-4.328 1.00 0.00 ATOM 294 1HG GLU 139-2.336 10.135-5.261 1.00 0.00 ATOM 295 2HG GLU 139-1.481 8.888-4.355 1.00 0.00 ATOM 296 QG GLU 139-1.908 9.511-4.808 1.00 0.00 ATOM 297 CD GLU 139-2.046 10.576-3.207 1.00 0.00 ATOM 298 OE1 GLU 139-0.888 10.671-2.751 1.00 0.00 ATOM 299 OE2 GLU 139-3.008 11.240-2.775 1.00 0.00 ATOM 300 C GLU 139-4.366 6.847-5.492 1.00 0.00 ATOM 301 O GLU 139-4.420 7.475-6.550 1.00 0.00 ATOM 302 N ARG+ 140-5. 076 5.750-5.275 1.00 0.00 ATOM 303 H ARG+ 140-5.002 5.290-4.410 1.00 0.00 ATOM 304 CA ARG+ 140-5.975 5.216-6.288 1.00 0.00 ATOM 305 HA ARG+ 140-5. 642 5.575-7.252 1.00 0.00 ATOM 306 CB ARG+ 140-5.946 3.682-6.283 1.00 0.00 ATOM 307 1HB ARG+ 140-6.452 3.329-5.395 1.00 0.00 ATOM 308 2HB ARG+ 140-4.919 3.351-6.256 1.00 0.00 ATOM 309 QB ARG+ 140-5.685 3.340-5.825 1.00 0.00 ATOM 310 CG ARG+ 140-6.620 3.051-7.491 1.00 0.00 ATOM 311 1HG ARG+ 140-7.634 3.422-7.557 1.00 0.00 ATOM 312 2HG ARG+ 140-6.637 1.980-7.361 1.00 0.00 ATOM 313 QG ARG+ 140-7.135 2.701-7.459 1.00 0.00 ATOM 314 CD ARG+ 140-5.888 3.382-8.779 1.00 0.00 ATOM 315 1HD ARG+ 140-4.889 3.715-8.535 1.00 0.00 ATOM 316 2HD ARG+ 140-6.419 4.181-9.285 1.00 0.00 ATOM 317 QD ARG+ 140-5.654 3.948-8.910 1.00 0.00 ATOM 318 NE ARG+ 140-5.803 2.227-9.673 1.00 0.00 ATOM 319 HE ARG+ 140-5.385 1.413-9.318 1. 00 0.00 ATOM 320 CZ ARG+ 140-6.243 2.232-10.932 1.00 0.00 ATOM 321 NH1 ARG+ 140-6.858 3.301-11.417 1.00 0.00 ATOM 322 1HH1 ARG+ 140-7.000 4.115-10.833 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.194 3.309-12.359 1.00 0.00 ATOM 324 QH1 ARG+ 140-7/097 3.712-11.596 1. 00 0.00 ATOM 325 NH2 ARG+ 140-6. 083 1.160-11.698 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.632 0.345-11.333 1.00 0.00 ATOM 327 2HH2 ARG+ 140-6.415 1. 164-12. 642 1.00 0.00 ATOM 328 QH2 ARG+ 140-6.023 0.754-11.987 1.00 0.00 ATOM 329 C ARG+ 140-7.392 5.712-6.041 1.00 0.00 ATOM 330 O ARG+ 140-8.217 5.004-5.461 1.00 0.00 ATOM 331 N MET 141-7. 678 6.931-6.483 1.00 0.00 ATOM 332 H MET 141-6.982 7.449-6.940 1.00 0.00 ATOM 333 CA MET 141-9.004 7.520-6.303 1.00 0.00 ATOM 334 HA MET 141-9.310 7.328-5.286 1.00 0.00 ATOM 335 CB MET 141-8.942 9.035-6.523 1.00 0.00 ATOM 336 1HB MET 141-9. 127 9.242-7.568 1.00 0.00 ATOM 337 2HB MET 141-7.954 9.387-6.266 1.00 0.00 ATOM 338 QB MET 141-8.540 9.314-6.917 1.00 0.00 ATOM 339 CG MET 141-9.956 9.814-5.697 1.00 0.00 ATOM 340 1HG MET 141-9.518 10.036-4.734 1.00 0.00 ATOM 341 2HG MET 141-10. 832 9.199-5.558 1.00 0.00 ATOM 342 QG MET 141-10.175 9.617-5.146 1.00 0.00 ATOM 343 SD MET 141-10.456 11.362-6.476 1.00 0.00 ATOM 344 QE MET 141-10.874 10.707-8.484 1.00 0.00 ATOM 345 CE MET 141-10.804 10.817-8.147 1.00 0.00 ATOM 346 1HE MET 141-10.903 9.741-8.163 1.00 0.00 ATOM 347 2HE MET 141-9.995 11.114-8.799 1.00 0.00 ATOM 348 3HE MET 141-11.724 11.268-8.490 1.00 0.00

ATOM 349 C MET 141-10.026 6.886-7.252 1.00 0.00 ATOM 350 O MET 141-10. 979 7.536-7.685 1. 00 0.00 ATOM 351 N ASP 142-9.824 5.613-7.553 1.00 0.00 ATOM 352 H ASP 142-9.054 5.155-7.162 1.00 0.00 ATOM 353 CA ASP 142-10.701 4.869-8.434 1.00 0.00 ATOM 354 HA ASP 142-11.379 5.562-8.908 1. 00 0.00 ATOM 355 CB ASP 142-9.879 4.155-9. 504 1.00 0.00 ATOM 356 1HB ASP 142-10.547 3.630-10.162 1.00 0.00 ATOM 357 2HB ASP 142-9.222 3.445-9.028 1.00 0.00 ATOM 358 QB ASP 142-9.884 3.537-9.595 1.00 0.00 ATOM 359 CG ASP 142-9.036 5.099-10. 330 1.00 0.00 ATOM 360 OD1 ASP 142-9.517 5.560-11.379 1.00 0. 00 ATOM 361 OD2 ASP 142-7.875 5.351-9. 940 1.00 0.00 ATOM 362 C ASP 142-11.495 3.835-7.653 1.00 0.00 ATOM 363 O ASP 142-12.719 3.755-7.764 1.00 0.00 ATOM 364 N VAL 143-10.784 3.029-6.874 1.00 0.00 ATOM 365 H VAL 143-9.811 3.134-6. 838 1.00 0.00 ATOM 366 CA VAL 143-11.416 1.976-6.095 1.00 0.00 ATOM 367 HA VAL 143-12. 346 1.723-6.585 1.00 0.00 ATOM 368 CB VAL 143-10. 533 0.707-6.051 1.00 0.00 ATOM 369 HB VAL 143-9.929 0.742-5. 154 1.00 0.00 ATOM 370 QG1 VAL 143-11.594-0.844-5.982 1.00 0.00 ATOM 371 QG2 VAL 143-9.378 0.636-7. 535 1.00 0.00 ATOM 372 CG1 VAL 143-11.393-0.546-5. 995 1.00 0.00 ATOM 373 1HG1 VAL 143-11.710-0.722-4.978 1.00 0.00 ATOM 374 2HG1 VAL 143-10.815-1.390-6.343 1.00 0.00 ATOM 375 3HG1 VAL 143-12.258-0.418-6.627 1.00 0.00 ATOM 376 CG2 VAL 143-9.599 0.650-7.252 1.00 0.00 ATOM 377 1HG2 VAL 143-9.909 1.382-7.983 1.00 0.00 ATOM 378 2HG2 VAL 143-9.637-0.336-7.690 1.00 0.00 ATOM 379 3HG2 VAL 143-8.589 0.864-6.933 1.00 0.00 ATOM 380 QQG VAL 143-10.486-0.104-6.759 1.00 0.00 ATOM 381 C VAL 143-11.729 2.456-4.675 1.00 0.00 ATOM 382 O VAL 143-11.202 3.469-4.220 1.00 0.00 ATOM 383 N CYS 144-12.617 1.741-3.995 1.00 0.00 ATOM 384 H CYS 144-13. 022 0.956-4.420 1.00 0.00 ATOM 38S CA CYS 144-13.034 2.105-2.643 1.00 0.00 ATOM 386 HA CYS 144-12.235 2.665-2.168 1.00 0.00 ATOM 387 CB CYS 144-14.286 2.982-2.739 1.00 0. 00 ATOM 388 1HB CYS 144-15.047 2.442-3.285 1.00 0.00 ATOM 389 2HB CYS 144-14.041 3.883-3.277 1.00 0.00 ATOM 390 QB CYS 144-14.544 3.162-3.281 1.00 0.00 ATOM 391 SG CYS 144-15.003 3.478-1.144 1.00 0.00 ATOM 392 C CYS 144-13.328 0.862-1.815 1.00 0.00 ATOM 393 O CYS 144-14. 424 0.311-1.891 1.00 0.00 ATOM 394 N GLU 145-12.350 0.417-1.033 1.00 0.00 ATOM 395 H GLU 145-11.492 0.885-1.015 1.00 0.00 ATOM 396 CA GLU 145-12.521-0.766-0.213 1. 00 0. 00 ATOM 397 HA GLU 145-13.572-1.009-0.197 1.00 0.00 ATOM 398 CB GLU 145-11.766-1.931-0.828 1.00 0.00 ATOM 399 1HB GLU 145-11.521-2.635-0.052 1.00 0.00 ATOM 400 2HB GLU 145-10.849-1.562-1.265 1.00 0.00 ATOM 401 QB GLU 145-11.185-2.099-0.658 1.00 0.00 ATOM 402 CG GLU 145-12.566-2.660-1.899 1.00 0.00 ATOM 403 1HG GLU 145-11. 921-3.374-2. 390 1.00 0.00 ATOM 404 2HG GLU 145-12.918-1.939-2.621 1.00 0.00 ATOM 405 QG GLU 145-12.419-2.657-2.505 1.00 0.00 ATOM 406 CD GLU 145-13.766-3.401-1.333 1.00 0.00 ATOM 407 OE1 GLU 145-14.212-3.059-0.214 1.00 0.00 ATOM 408 OE2 GLU 145-14.250-4.336-2.000 1.00 0.00 ATOM 409 C GLU 145-12.051-0.535 1.214 1.00 0.00 ATOM 410 O GLU 145-11.535 0.533 1.545 1.00 0.00 ATOM 411 N THR 146-12.246-1.545 2.052 1.00 0.00 ATOM 412 H THR 146-12.668-2.363 1.714 1.00 0.00 ATOM 413 CA THR 146-11.864-1.479 3.457 1.00 0.00 ATOM 414 HA THR 146-12.240-0.548 3.859 1.00 0.00 ATOM 415 CB THR 146-12.510-2.646 4.214 1.00 0.00 ATOM 416 HB THR 146-11. 969-3. 554 3.984 1.00 0.00 ATOM 417 QG2 THR 146-12. 520-2. 440 6.080 1.00 0.00 ATOM 418 OG1 THR 146-13.854-2.814 3.806 1.00 0.00 ATOM 419 1HG THR 146-14.438-2.371 4.438 1.00 0.00 ATOM 420 CG2 THR 146-12. 517-2.480 5.720 1.00 0.00

ATOM 421 1HG2 THR 146-11.506-2.351 6.075 1.00 0.00 ATOM 422 2HG2 THR 146-12.950-3.357 6.178 1.00 0.00 ATOM 423 3HG2 THR 146-13.104-1.610 5.985 1.00 0.00 ATOM 424 C THR 146-10.344-1.509 3.624 1.00 0.00 ATOM 425 O THR 146-9.612-1.897 2.711 1.00 0.00 ATOM 426 N HIS+ 147-9.885-1.107 4.809 1.00 0.00 ATOM 427 H HIS+ 147-10.531-0.819 5.489 1.00 0.00 ATOM 428 CA HIS+ 147-8. 460-1.088 5.139 1.00 0.00 ATOM 429 HA HIS+ 147-7.972-0.383 4.484 1.00 0.00 ATOM 430 CB HIS+ 147-8. 273-0.638 6.593 1.00 0.00 ATOM 431 1HB HIS+ 147-8.311-1.507 7.235 1.00 0.00 ATOM 432 2HB HIS+ 147-9.076 0.032 6.860 1.00 0.00 ATOM 433 QB HIS+ 147-8.693-0.738 7.048 1.00 0.00 ATOM 434 CG HIS+ 147-6. 980 0.073 6.859 1.00 0.00 ATOM 435 ND1 HIS+ 147-6.865 1.447 6.883 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.744-0.410 7.140 1.00 0.00 ATOM 437 1HD HIS+ 147-7.591 2.090 6.707 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.617 1.779 7.170 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.917 0.671 7.331 1.00 0.00 ATOM 440 2HD HIS+ 147-5.458-1.453 7.188 1.00 0.00 ATOM 441 1HE HIS+ 147-5.236 2.786 7.259 1.00 0.00 ATOM 442 2HE HIS+ 147-3.996 0.629 7.668 1.00 0.00 ATOM 443 C HIS+ 147-7.835-2.468 4.944 1.00 0.00 ATOM 444 O HIS+ 147-6.657-2.585 4.616 1.00 0.00 ATOM 445 N LEU 148-8.636-3.509 5.145 1.00 0.00 ATOM 446 H LEU 148-9.568-3.351 5.400 1.00 0. 00 ATOM 447 CA LEU 148-8.168-4.878 4.989 1.00 0.00 ATOM 448 HA LEU 148-7.224-4.967 5. 506 1.00 0.00 ATOM 449 CB LEU 148-9.173-5.852 5.613 1.00 0.00 ATOM 450 1HB LEU 148-10.159-5.596 5.256 1.00 0.00 ATOM 451 2HB LEU 148-9.151-5.721 6.685 1.00 0.00 ATOM 452 QB LEU 148-9.655-5.659 5.971 1.00 0.00 ATOM 453 CG LEU 148-8.923-7.328 5.305 1.00 0.00 ATOM 454 HG LEU 148-8.432-7.409 4.346 1.00 0.00 ATOM 455 QD1 LEU 148-7.796-8.094 6.600 1.00 0.00 ATOM 456 QD2 LEU 148-10.549-8.269 5.209 1.00 0.00 ATOM 457 CD1 LEU 148-8.012-7.946 6.352 1.00 0.00 ATOM 458 1HD1 LEU 148-7.517-7.164 6.907 1.00 0.00 ATOM 459 2HD1 LEU 148-7.273-8.565 5.865 1.00 0.00 ATOM 460 3HD1 LEU 148-8.599-8.552 7.027 1.00 0.00 ATOM 461 CD2 LEU 148-10.238-8.087 5.227 1.00 0.00 ATOM 462 1HD2 LEU 148-10. 890-7. 609 4.512 1.00 0.00 ATOM 463 2HD2 LEU 148-10.709-8.092 6.199 1.00 0.00 ATOM 464 3HD2 LEU 148-10.047-9.104 4.916 1.00 0.00 ATOM 465 QQD LEU 148-9.172-8.181 5.905 1.00 0.00 ATOM 466 C LEU 148-7.955-5.212 3.518 1.00 0.00 ATOM 467 O LEU 148-7.004-5.903 3.164 1.00 0.00 ATOM 468 N HIS+ 149-8.844-4.713 2.665 1.00 0.00 ATOM 469 H HIS+ 149-9.578-4.164 3.007 1.00 0.00 ATOM 470 CA HIS+ 149-8.750-4.960 1.230 1.00 0.00 ATOM 471 HA HIS+ 149-8.767-6.029 1.079 1.00 0.00 ATOM 472 CB HIS+ 149-9.934-4.341 0.499 1.00 0.00 ATOM 473 1HB HIS+ 149-9.571-3.609-0.209 1.00 0.00 ATOM 474 2HB HIS+ 149-10. 578-3.849 1.213 1.00 0. 00 ATOM 475 QB HIS+ 149-10.074-3.729 0.502 1.00 0.00 ATOM 476 CG HIS+ 149-10.754-5.339-0.251 1.00 0.00 ATOM 477 ND1 HIS+ 149-10.291-6.018-1. 354 1.00 0.00 ATOM 478 CD2 HIS+ 149-12.031-5.743-0.071 1.00 0.00 ATOM 479 1HD HIS+ 149-9.391-5.941-1.741 1.00 0.00 ATOM 480 CE1 HIS+ 149-11.252-6.793-1.825 1.00 0.00 ATOM 481 NE2 HIS+ 149-12.326-6.645-1.064 1.00 0.00 ATOM 482 2HD HIS+ 149-12.705-5.405 0.705 1.00 0.00 ATOM 483 1HE HIS+ 149-11.175-7.439-2.687 1.00 0.00 ATOM 484 2HE HIS+ 149-13.239-6.856-1.358 1.00 0.00 ATOM 485 C HIS+ 149-7.450-4.412 0.670 1.00 0.00 ATOM 486 O HIS+ 149-6.673-5.152 0.078 1.00 0.00 ATOM 487 N TRP 150-7.213-3.118 0. 866 1.00 0.00 ATOM 488 H TRP 150-7.876-2.576 1.349 1.00 0.00 ATOM 489 CA TRP 150-5.985-2.487 0.381 1.00 0.00 ATOM 490 HA TRP 150-5. 936-2.628-0.689 1.00 0.00 ATOM 491 CB TRP 150-5.965-0.993 0.700 1.00 0.00 ATOM 492 1HB TRP 150-5.016-0.583 0.386 1.00 0.00

ATOM 493 2HB TRP 150-6. 065-0.862 1.767 1.00 0.00 ATOM 494 QB TRP 150-5.540-0.723 1.077 1.00 0.00 ATOM 495 CG TRP 150-7.049-0.197 0.041 1.00 0.00 ATOM 496 CD1 TRP 150-7.524 1.013 0.452 1.00 0.00 ATOM 497 CD2 TRP 150-7.788-0.537-1.140 1.00 0.00 ATOM 498 CE3 TRP 150-7.778-1.624-2.019 1.00 0.00 ATOM 499 CE2 TRP 150-8. 690 0.515-1.378 1.00 0.00 ATOM 500 NE1 TRP 150-8.510 1.445-0.394 1.00 0.00 ATOM 501 HD TRP 150-7. 165 1.543 1.322 1.00 0.00 ATOM 502 3HE TRP 150-7.103-2.451-1.875 1.00 0.00 ATOM 503 CZ3 TRP 150-8. 651-1.626-3.083 1.00 0.00 ATOM 504 CZ2 TRP 150-9.566 0.511-2.452 1.00 0.00 ATOM 505 1HE TRP 150-9.007 2.285-0.306 1.00 0.00 ATOM 506 3HZ TRP 150-8. 662-2.459-3.768 1.00 0.00 ATOM 507 CH2 TRP 150-9. 533-0.565-3.291 1.00 0.00 ATOM 508 2HZ TRP 150-10.255 1.323-2.631 1.00 0.00 ATOM 509 HH TRP 150-10.201-0.610-4.138 1.00 0.00 ATOM 510 C TRP 150-4. 771-3.145 0.997 1.00 0.00 ATOM 511 O TRP 150-3. 740-3.261 0.351 1.00 0.00 ATOM 512 N HIS+ 151-4.906-3.597 2.238 1.00 0.00 ATOM 513 H HIS+ 151-5.765-3.489 2.698 1.00 0.00 ATOM 514 CA HIS+ 151-3.813-4.274 2.915 1.00 0.00 ATOM 515 HA HIS+ 151-2.964-3.609 2.930 1.00 0.00 ATOM 516 CB HIS+ 151-4.216-4.633 4.356 1.00 0.00 ATOM 517 1HB HIS+ 151-5.078-5.286 4.323 1.00 0.00 ATOM 518 2HB HIS+ 151-4.484-3.728 4.879 1.00 0.00 ATOM 519 QB HIS+ 151-4.781-4.507 4.601 1.00 0.00 ATOM 520 CG HIS+ 151-3.147-5.325 5.157 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.793-4.938 6.432 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.370-6.397 4.865 1.00 0.00 ATOM 523 1HD HIS+ 151-3.178-4.188 6.932 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.847-5.742 6.885 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.574-6.635 5.956 1.00 0.00 ATOM 526 2HD HIS+ 151-2.371-6.952 3.934 1.00 0.00 ATOM 527 1HE HIS+ 151-1.365-5.671 7.850 1.00 0.00 ATOM 528 2HE HIS+ 151-0.988-7.411 6.074 1.00 0.00 ATOM 529 C HIS+ 151-3.450-5.528 2.134 1.00 0.00 ATOM 530 O HIS+ 151-2.278-5.788 1.871 1.00 0.00 ATOM 531 N THR 152-4.467-6.291 1.761 1.00 0.00 ATOM 532 H THR 152-5.379-6.023 1.998 1.00 0.00 ATOM 533 CA THR 152-4.264-7.510 1.003 1.00 0.00 ATOM 534 HA THR 152-3.520-8.097 1.519 1.00 0.00 ATOM 535 CB THR 152-5.564-8.315 0.924 1.00 0.00 ATOM 536 HB THR 152-6.203-7.878 0.169 1.00 0.00 ATOM 537 QG2 THR 152-5.300-10.117 0.482 1.00 0.00 ATOM 538 OG1 THR 152-6.246-8.283 2.168 1.00 0.00 ATOM 539 1HG THR 152-6.555-7.387 2.346 1.00 0.00 ATOM 540 CG2 THR 152-5.350-9.770 0.568 1.00 0.00 ATOM 541 1HG2 THR 152-6.270-10.316 0.717 1.00 0.00 ATOM 542 2HG2 THR 152-4.579-10.186 1.198 1.00 0.00 ATOM 543 3HG2 THR 152-5.050-9.847-0.469 1.00 0.00 ATOM 544 C THR 152-3.736-7.195-0.390 1.00 0.00 ATOM 545 O THR 152-2.745-7.774-0.802 1.00 0.00 ATOM 546 N VAL 153-4.379-6.259-1.094 1.00 0.00 ATOM 547 H VAL 153-5. 159-5. 807-0.699 1.00 0.00 ATOM 548 CA VAL 153-3.935-5.877-2.436 1.00 0.00 ATOM 549 HA VAL 153-4. 010-6.746-3.068 1.00 0.00 ATOM 550 CB VAL 153-4.819-4.756-3.032 1.00 0.00 ATOM 551 HB VAL 153-4.707-3.873-2.420 1.00 0.00 ATOM 552 QG1 VAL 153-4.279-4.331-4.783 1.00 0.00 ATOM 553 QG2 VAL 153-6.628-5.266-3.011 1.00 0.00 ATOM 554 CG1 VAL 153-4.383-4.412-4.449 1.00 0.00 ATOM 555 1HG1 VAL 153-3.346-4.686-4.583 1.00 0.00 ATOM 556 2HG1 VAL 153-4.499-3.351-4.614 1.00 0.00 ATOM 557 3HG1 VAL 153-4.993-4.956-5.154 1.00 0.00 ATOM 558 CG2 VAL 153-6.282-5.167-3.016 1.00 0.00 ATOM 559 1HG2 VAL 153-6.670-5.078-2.011 1.00 0.00 ATOM 560 2HG2 VAL 153-6.370-6.193-3.345 1.00 0.00 ATOM 561 3HG2 VAL 153-6.844-4.526-3.678 1.00 0.00 ATOM 562 QQG VAL 153-5.454-4.799-3.897 1.00 0.00 ATOM 563 C VAL 153-2.483-5.424-2.406 1.00 0.00 ATOM 564 O VAL 153-1.660-5.879-3.200 1.00 0.00

ATOM 565 N ALA 154-2.177-4.540-1.471 1.00 0.00 ATOM 566 H ALA 154-2.885-4.229-0.861 1.00 0.00 ATOM 567 CA ALA 154-0.826-4.030-1.305 1.00 0.00 ATOM 568 HA ALA 154-0. 531-3.534-2.217 1.00 0.00 ATOM 569 QB ALA 154-0.788-2.783 0.094 1.00 0.00 ATOM 570 CB ALA 154-0.795-3.023-0.174 1.00 0.00 ATOM 571 1HB ALA 154-0.213-2.164-0.475 1.00 0.00 ATOM 572 2HB ALA 154-0.347-3.474 0.698 1.00 0.00 ATOM 573 3HB ALA 154-1.803-2.711 0.059 1.00 0.00 ATOM 574 C ALA 154 0.148-5.162-1.014 1.00 0.00 ATOM 575 O ALA 154 1.186-5.295-1.667 1.00 0.00 ATOM 576 N LYS+ 155-0. 198-5.976-0.023 1.00 0.00 ATOM 577 H LYS+ 155-1.042-5.811 0.455 1.00 0.00 ATOM 578 CA LYS+ 155 0.630-7.104 0.374 1.00 0.00 ATOM 579 HA LYS+ 155 1.603-6.720 0.660 1.00 0.00 ATOM 580 CB LYS+ 155 0.001-7.832 1.566 1.00 0.00 ATOM 581 1HB LYS+ 155-0.979-8.185 1.274 1.00 0.00 ATOM 582 2HB LYS+ 155-0.110-7.132 2.380 1.00 0.00 ATOM 583 QB LYS+ 155-0.544-7.659 1.827 1.00 0.00 ATOM 584 CG LYS+ 155 0.805-9.024 2.069 1.00 0.00 ATOM 585 1HG LYS+ 155 1.411-8.709 2.906 1.00 0.00 ATOM 586 2HG LYS+ 155 1.442-9.380 1.272 1.00 0.00 ATOM 587 QG LYS+ 155 1.427-9.045 2.089 1.00 0.00 ATOM 588 CD LYS+ 155-0.109-10.156 2.516 1.00 0.00 ATOM 589 1HD LYS+ 155-1.136-9.826 2.437 1.00 0. 00 ATOM 590 2HD LYS+ 155 0.112-10.403 3.544 1.00 0.00 ATOM 591 QD LYS+ 155-0.512-10.115 2.991 1.00 0.00 ATOM 592 CE LYS+ 155 0.075-11.400 1.658 1.00 0.00 ATOM 593 1HE LYS+ 155-0.152-11.150 0.630 1.00 0.00 ATOM 594 2HE LYS+ 155-0.609-12.163 2.001 1.00 0.00 ATOM 595 QE LYS+ 155-0.380-11.657 1.316 1.00 0.00 ATOM 596 NZ LYS+ 155 1.467-11.927 1.733 1.00 0.00 ATOM 597 1HZ LYS+ 155 2.081-11.423 1.047 1.00 0.00 ATOM 598 2HZ LYS+ 155 1.479-12.941 1.507 1.00 0.00 ATOM 599 3HZ LYS+ 155 1.853-11.793 2.687 1.00 0.00 ATOM 600 QZ LYS+ 155 1.804-12.053 1.747 1.00 0.00 ATOM 601 C LYS+ 155 0.809-8.063-0.788 1.00 0.00 ATOM 602 O LYS+ 155 1.928-8.461-1.083 1.00 0.00 ATOM 603 N GLU 156-0.294-8.424-1.437 1.00 0.00 ATOM 604 H GLU 156-1.164-8.062-1.144 1.00 0.00 ATOM 605 CA GLU 156-0.260-9.335-2.575 1.00 0.00 ATOM 606 HA GLU 156 0.097-10.291-2.222 1.00 0.00 ATOM 607 CB GLU 156-1.657-9.518-3.165 1.00 0.00 ATOM 608 1HB GLU 156-1.564-9.865-4.184 1.00 0.00 ATOM 609 2HB GLU 156-2. 166-8.565-3.164 1.00 0.00 ATOM 610 QB GLU 156-1.865-9.215-3.674 1.00 0.00 ATOM 611 CG GLU 156-2.515-10.514-2.401 1.00 0.00 ATOM 612 1HG GLU 156-2.348-10.380-1.344 1.00 0.00 ATOM 613 2HG GLU 156-2.229-11.514-2.689 1.00 0.00 ATOM 614 QG GLU 156-2.288-10.947-2.016 1.00 0.00 ATOM 615 CD GLU 156-3.992-10.336-2.682 1.00 0.00 ATOM 616 OE1 GLU 156-4.748-11.311-2.507 1.00 0.00 ATOM 617 OE2 GLU 156-4. 393-9.218-3.072 1.00 0.00 ATOM 618 C GLU 156 0.692-8.830-3.648 1.00 0.00 ATOM 619 O GLU 156 1.548-9.573-4.103 1.00 0.00 ATOM 620 N THR 157 0.547-7.563-4.031 1.00 0.00 ATOM 621 H THR 157-0.158-7.017-3.617 1.00 0.00 ATOM 622 CA THR 157 1.413-6.960-5.048 1.00 0.00 ATOM 623 HA THR 157 1.216-7.457-5.987 1.00 0.00 ATOM 624 CB THR 157 1.090-5.468-5.198 1.00 0.00 ATOM 625 HB THR 157 1.382-4.954-4.293 1.00 0.00 ATOM 626 QG2 THR 157 1.980-4.651-6.631 1.00 0.00 ATOM 627 OG1 THR 157-0.298-5.268-5.397 1.00 0.00 ATOM 628 1HG THR 157-0.791-5.623-4.643 1.00 0.00 ATOM 629 CG2 THR 157 1.809-4.808-6.356 1.00 0.00 ATOM 630 1HG2 THR 157 2.264-3.887-6.021 1.00 0.00 ATOM 631 2HG2 THR 157 1.101-4.594-7.143 1.00 0.00 ATOM 632 3HG2 THR 157 2.574-5.472-6.731 1.00 0.00 ATOM 633 C THR 157 2.894-7.144-4.698 1.00 0.00 ATOM 634 O THR 157 3.721-7.431-5.563 1.00 0.00 ATOM 635 N CYS 158 3.227-6.974-3.426 1.00.0.00 ATOM 636 H CYS 158 2.529-6.738-2.773 1.00 0.00

ATOM 637 CA CYS 158 4.605-7.121-2.977 1.00 0.00 ATOM 638 HA CYS 158 5.243-6.677-3.727 1.00 0.00 ATOM 639 CB CYS 158 4.799-6.362-1.666 1.00 0.00 ATOM 640 1HB CYS 158 5.694-6.707-1.182 1.00 0.00 ATOM 641 2HB CYS 158 3.954-6.554-1.024 1.00 0.00 ATOM 642 QB CYS 158 4.824-6.631-1.103 1.00 0.00 ATOM 643 SG CYS 158 4.931-4.549-1.888 1.00 0.00 ATOM 644 C CYS 158 4.997-8.601-2.829 1.00 0.00 ATOM 645 O CYS 158 6.079-9.001-3.253 1.00 0.00 ATOM 646 N SER 159 4.116-9.407-2.232 1.00 0.00 ATOM 647 H SER 159 3.269-9.034-1.915 1.00 0.00 ATOM 648 CA SER 159 4.383-10.837-2.033 1.00 0.00 ATOM 649 HA SER 159 5.353-10.922-1.564 1.00 0. 00 ATOM 650 CB SER 159 3.339-11.470-1.113 1.00 0.00 ATOM 651 1HB SER 159 3.744-12.383-0.697 1.00 0.00 ATOM 652 2HB SER 159 2.453-11.700-1.688 1.00 0.00 ATOM 653 QB SER 159 3.099--12.042-1.192 1.00 0.00 ATOM 654 OG SER 159 2.981-10.598-0.048 1.00 0.00 ATOM 655 HG SER 159 2.754-9.730-0.413 1.00 0.00 ATOM 656 C SER 159 4.420-11.611-3.353 1.00 0.00 ATOM 657 O SER 159 5.110-12.624-3.451 1.00 0.00 ATOM 658 N GLU 160 3.683-11.136-4.358 1.00 0.00 ATOM 659 H GLU 160 3.150-10.324-4.222 1.00 0.00 ATOM 660 CA GLU 160 3.655-11.792-5.665 1.00 0.00 ATOM 661 HA GLU 160 3.393-12.829-5.517 1.00 0.00 ATOM 662 CB GLU 160 2.624-11.128-6.583 1.00 0. 00 ATOM 663 1HB GLU 160 3.107-10.335-7.134 1.00 0.00 ATOM 664 2HB GLU 160 1.836-10.704-5.978 1.00 0.00 ATOM 665 QB GLU 160 2.472-10.520-6.556 1.00 0. 00 ATOM 666 CG GLU 160 1.992-12.081-7.585 1.00 0.00 ATOM 667 1HG GLU 160 1.351-12.769-7.055 1.00 0.00 ATOM 668 2HG GLU 160 2.775-12.631-8.084 1.00 0.00 ATOM 669 QG GLU 160 2.063-12.700-7.569 1.00 0.00 ATOM 670 CD GLU 160 1.168-11.360-8.630 1.00 0.00 ATOM 671 OE1 GLU 160 1.549-10.235-9.012 1.00 0.00 ATOM 672 OE2 GLU 160 0.141-11.920-9.064 1.00 0.00 ATOM 673 C GLU 160 5.043-11.713-6.285 1.00 0.00 ATOM 674 O GLU 160 5.458-12.574-7.062 1.00 0.00 ATOM 675 N LYS+ 161 5.766-10.679-5.887 1.00 0.00 ATOM 676 H LYS+ 161 5.377-10.055-5.241 1.00 0.00 ATOM 677 CA LYS+ 161 7.122-10.465-6.332 1. 00 0.00 ATOM 678 HA LYS+ 161 7.252-10.986-7.269 1.00 0. 00 ATOM 679 CB LYS+ 161 7.398-8.968-6.531 1.00 0.00 ATOM 680 1HB LYS+ 161 7.767-8.557-5.604 1.00 0.00 ATOM 681 2HB LYS+ 161 6.471-8.476-6.787 1.00 0.00 ATOM 682 QB LYS+ 161 7.119-8.517-6.195 1. 00 0.00 ATOM 683 CG LYS+ 161 8.416-8.676-7.628 1. 00 0.00 ATOM 684 1HG LYS+ 161 7.886-8.440-8.541 1. 00 0.00 ATOM 685 2HG LYS+ 161 9.022-9.555-7.781 1.00 0.00 ATOM 686 QG LYS+ 161 8.454-8.998-8.161 1. 00 0. 00 ATOM 687 CD LYS+ 161 9.321-7.506-7.263 1.00 0.00 ATOM 688 1HD LYS+ 161 8.987-7.088-6.322 1.00 0.00 ATOM 689 2HD LYS+ 161 9.246-6.755-8.036 1.00 0.00 ATOM 690 QD LYS+ 161 9.117-6.922-7.179 1. 00 0.00 ATOM 691 CE LYS+ 161 10.781-7.926-7.126 1.00 0.00 ATOM 692 1HE LYS+ 161 11.021-8.003-6.074 1.00 0.00 ATOM 693 2HE LYS+ 161 11.402-7.168-7.579 1. 00 0.00 ATOM 694 QE LYS+ 161 11.212-7.586-6.826 1.00 0.00 ATOM 695 NZ LYS+ 161 11. 060-9. 234-7.785 1.00 0.00 ATOM 696 1HZ LYS+ 161 11. 989-9. 209-8.251 1.00 0.00 ATOM 697 2HZ LYS+ 161 10. 335-9. 443-8. 497 1.00 0.00 ATOM 698 3HZ LYS+ 161 11. 065-10. 006-7. 070 1.00 0.00 ATOM 699 QZ LYS+ 161 11. 130-9. 553-7.939 1.00 0.00 ATOM 700 C LYS+ 161 8.067-11.059-5.294 1.00 0.00 ATOM 701 O LYS+ 161 7.837-12.150-4.786 1.00 0.00 ATOM 702 N SER 162 9.124-10.341-4.973 1.00 0.00 ATOM 703 H SER 162 9.261-9.475-5.395 1. O0 0.00 ATOM 704 CA SER 162 10. 073-10. 814-3.987 1.00 0. 00 ATOM 705 HA SER 162 9.715-11.762-3.617 1.00 0.00 ATOM 706 CB SER 162 11. 449-11. 018-4.625 1.00 0.00 ATOM 707 1HB SER 162 11. 934-11. 868-4.163 1.00 0.00 ATOM 708 2HB SER 162 12. 051-10. 135-4.466 1.00 0.00

ATOM 709 QB SER 162 11.993-11.002-4.314 1.00 0.00 ATOM 710 OG SER 162 11.332-11.257-6.025 1.00 0.00 ATOM 711 HG SER 162 11.265-12.210-6.175 1.00 0.00 ATOM 712 C SER 162 10.171-9.841-2.818 1.00 0.00 ATOM 713 O SER 162 11.264-9.458-2.420 1.00 0.00 ATOM 714 N THR 163 9.027-9.432-2.270 1.00 0.00 ATOM 715 H THR 163 8.171-9.759-2.628 1.00 0.00 ATOM 716 CA THR 163 9.022-8.508-1.140 1.00 0.00 ATOM 717 HA THR 163 9.953-8.642-0.606 1.00 0.00 ATOM 718 CB THR 163 8.928-7.046-1.600 1.00 0.00 ATOM 719 HB THR 163 8.892-6.422-0.715 1.00 0.00 ATOM 720 QG2 THR 163 10.373-6.468-2.645 1.00 0.00 ATOM 721 OG1 THR 163 7.752-6.820-2.351 1.00 0.00 ATOM 722 1HG THR 163 7.739-5.911-2.666 1.00 0.00 ATOM 723 CG2 THR 163 10.094-6.578-2.445 1.00 0.00 ATOM 724 1HG2 THR 163 9.744-6.318-3.432 1.00 0.00 ATOM 725 2HG2 THR 163 10.825-7.372-2.519 1.00 0.00 ATOM 726 3HG2 THR 163 10.549-5.713-1.984 1.00 0.00 ATOM 727 C THR 163 7.872-8.813-0.181 1.00 0.00 ATOM 728 O THR 163 6.939-9.544-0.508 1.00 0.00 ATOM 729 N ASN 164 7.954-8.242 1.011 1.00 0.00 ATOM 730 H ASN 164 8.731-7.674 1.210 1.00 0.00 ATOM 731 CA ASN 164 6.932-8.436 2.042 1.00 0.00 ATOM 732 HA ASN 164 6.069-8.898 1.576 1.00 0.00 ATOM 733 CB ASN 164 7.464-9.352 3.150 1.00 0.00 ATOM 734 1HB ASN 164 7.188-10.372 2.931 1.00 0.00 ATOM 735 2HB ASN 164 7.029-9.059 4.094 1.00 0.00 ATOM 736 QB ASN 164 7.109-9.716 3.513 1.00 0.00 ATOM 737 CG ASN 164 8.974-9.279 3.273 1.00 0.00 ATOM 738 OD1 ASN 164 9.654-10.297 3.307 1.00 0.00 ATOM 739 ND2 ASN 164 9.504-8.064 3.347 1.00 0.00 ATOM 740 1HD2 ASN 164 8.897-7.295 3.336 1.00 0.00 ATOM 741 2HD2 ASN 164 10.476-7.986 3.356 1.00 0.00 ATOM 742 QD2 ASN 164 9.687-7.641 3.346 1.00 0.00 ATOM 743 C ASN 164 6.526-7.097 2.645 1.00 0.00 ATOM 744 O ASN 164 7.386-6.289 2.994 1.00 0.00 ATOM 745 N LEU 165 5.222-6.860 2.762 1.00 0.00 ATOM 746 H LEU 165 4. 586-7.540 2.465 1.00 0.00 ATOM 747 CA LEU 165 4.714-5.605 3.324 1.00 0.00 ATOM 748 HA LEU 165 5.162-4.785 2.782 1.00 0.00 ATOM 749 CB LEU 165 3.194-5.518 3.188 1.00 0.00 ATOM 750 1HB LEU 165 2.772-5.368 4.171 1.00 0.00 ATOM 751 2HB LEU 165 2.828-6.455 2.793 1.00 0.00 ATOM 752 QB LEU 165 2.800-5.912 3.482 1.00 0. 00 ATOM 753 CG LEU 165 2.700-4.396 2.297 1.00 0.00 ATOM 754 HG LEU 165 3.189-3.475 2.578 1.00 0.00 ATOM 755 QD1 LEU 165 3.129-4.762 0.513 1.00 0.00 ATOM 756 QD2 LEU 165 0.848-4.162 2.506 1.00 0.00 ATOM 757 CD1 LEU 165 3.047-4.692 0.857 1.00 0.00 ATOM 758 1HD1 LEU 165 3.785-3.983 0.511 1.00 0.00 ATOM 759 2HD1 LEU 165 2.157-4.609 0.248 1.00 0.00 ATOM 760 3HD1 LEU 165 3.444-5.692 0.780 1.00 0.00 ATOM 761 CD2 LEU 165 1.203-4.207 2.466 1.00 0.00 ATOM 762 1HD2 LEU 165 0.957-4.199 3.517 1.00 0.00 ATOM 763 2HD2 LEU 165 0.680-5.017 1.979 1.00 0.00 ATOM 764 3HD2 LEU 165 0.906-3.269 2.020 1.00 0.00 ATOM 765 QQD LEU 165 1.988-4.462 1.510 1.00 0.00 ATOM 766 C LEU 165 5.083-5.466 4.786 1.00 0.00 ATOM 767 O LEU 165 4.785-6.338 5.599 1.00 0.00 ATOM 768 N HIS+ 166 5.718-4.355 5.108 1.00 0.00 ATOM 769 H HIS+ 166 5.917-3.695 4.411 1.00 0.00 ATOM 770 CA HIS+ 166 6.119-4.076 6. 470 1.00 0.00 ATOM 771 HA HIS+ 166 5.853-4.928 7.077 1.00 0.00 ATOM 772 CB HIS+ 166 7.636-3.861 6.542 1.00 0.00 ATOM 773 1HB HIS+ 166 7.896-2.993 5.950 1.00 0.00 ATOM 774 2HB HIS+ 166 8.136-4.727 6.139 1.00 0.00 ATOM 775 QB HIS+ 166 8.016-3.860 6.045 1.00 0.00 ATOM 776 CG HIS+ 166 8.152-3.638 7.930 1.00 0.'00 ATOM 777 ND1 HIS+ 166 8.225-4.630 8.884 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.613-2.515 8.522 1.00 0.00 ATOM 779 1HD HIS+ 166 7.958-5.565 8.760 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.709-4.122 10.005 1.00 0.00

ATOM 781 NE2 HIS+ 166 8.953-2.836 9.810 1.00 0.00 ATOM 782 2HD HIS+ 166 8.684-1. 533 8.064 1.00 0.00 ATOM 783 1HE HIS+ 166 8.875-4.663 10.924 1.00 0.00 ATOM 784 2HE HIS+ 166 9.118-2.182 10.522 1.00 0.00 ATOM 785 C HIS+ 166 5.373-2.847 6.988 1.00 0.00 ATOM 786 O HIS+ 166 4.767-2.886 8.059 1.00 0.00 ATOM 787 N ASP 167 5.417-1.763 6.216 1.00 0.00 ATOM 788 H ASP 167 5.914-1.798 5.370 1.00 0.00 ATOM 789 CA ASP 167 4.744-0.520 6.605 1.00 0.00 ATOM 790 HA ASP 167 4.269-0.693 7.558 1.00 0.00 ATOM 791 CB ASP 167 5.748 0.631 6.759 1.00 0.00 ATOM 792 1HB ASP 167 5.356 1.344 7.469 1.00 0.00 ATOM 793 2HB ASP 167 5.872 1.119 5.804 1.00 0.00 ATOM 794 QB ASP 167 5.614 1.231 6.637 1.00 0.00 ATOM 795 CG ASP 167 7.112 0.182 7.240 1.00 0.00 ATOM 796 OD1 ASP 167 7.364 0.256 8.459 1.00 0.00 ATOM 797 OD2 ASP 167 7.933-0.241 6.396 1.00 0.00 ATOM 798 C ASP 167 3.675-0.121 5.590 1.00 0.00 ATOM 799 O ASP 167 3.941 0.620 4.647 1.00 0.00 ATOM 800 N TYR 168 2.467-0.619 5.792 1.00 0.00 ATOM 801 H TYR 168 2.323-1.202 6.566 1.00 0.00 ATOM 802 CA TYR 168 1.335-0.320 4.912 1.00 0.00 ATOM 803 HA TYR 168 1.721-0.074 3.924 1.00 0.00 ATOM 804 CB TYR 168 0.427-1.547 4.809 1.00 0.00 ATOM 805 1HB TYR 168 0.740-2.152 3.972 1.00 0.00 ATOM 806 2HB TYR 168-0.592-1.221 4.652 1.00 0.00 ATOM 807 QB TYR 168 0.074-1.687 4.312 1.00 0.00 ATOM 808 QD TYR 168 0.463-2.510 6.198 1.00 0.00 ATOM 809 QE TYR 168 0.537-3.893 8.229 1.00 0.00 ATOM 810 QR TYR 168 0.500-3.201 7.214 1.00 0.00 ATOM 811 CG TYR 168 0.457-2.411 6.053 1.00 0.00 ATOM 812 CD1 TYR 168 1.284-3.526 6.129 1.00 0.00 ATOM 813 1HD TYR 168 1.902-3.781 5.281 1.00 0.00 ATOM 814 CE1 TYR 168 1.328-4.304 7.268 1.00 0.00 ATOM 815 1HE TYR 168 1.980-5.166 7.309 1.00 0.00 ATOM 816 CZ TYR 168 0.539-3.976 8.350 1.00 0.00 ATOM 817 CE2 TYR 168-0.290-2.877 8.299 1.00 0.00 ATOM 818 2HE TYR 168-0.907-2.620 9.148 1.00 0.00 ATOM 819 CD2 TYR 168-0.328-2.101 7.157 1.00 0.00 ATOM 820 2HD TYR 168-0.976-1.238 7.115 1.00 0.00 ATOM 821 OH TYR 168 0.578-4.750 9.483 1.00 0.00 ATOM 822 HH TYR 168 1.381-4.556 9.976 1.00 0.00 ATOM 823 C TYR 168 0.534 0.868 5.434 1.00 0.00 ATOM 824 O TYR 168 0.386 1.048 6.643 1.00 0.00 ATOM 825 N GLY 169.-0.002 1.654 4.521 1.00 0.00 ATOM 826 H GLY 169 0.133 1.451 3.569 1.00 0.00 ATOM 827 CA GLY 169-0. 801 2.798 4.893 1.00 0.00 ATOM 828 1HA GLY 169-0. 176 3.679 4.911 1.00 0.00 ATOM 829 2HA GLY 169-1. 217 2.636 5.877 1.00 0.00 ATOM 830 QA GLY 169-0.696 3.157 5.394 1.00 0.00 ATOM 831 C GLY 169-1.916 3.005 3.904 1.00 0.00 ATOM 832 O GLY 169-1.748 2.735 2.723 1.00 0.00 ATOM 833 N MET 170-3.057 3.467 4.366 1.00 0.00 ATOM 834 H MET 170-3. 148 3.666 5.320 1.00 0. 00 ATOM 835 CA MET 170-4.185 3.694 3.476 1.00 0.00 ATOM 836 HA MET 170-3.868 3.453 2.460 1.00 0.00 ATOM 837 CB MET 170-5.379 2.816 3.870 1.00 0.00 ATOM 838 1HB MET 170-6.289 3.350 3.634 1.00 0.00 ATOM 839 2HB MET 170-5.345 2.645 4.935 1.00 0.00 ATOM 840 QB MET 170-5. 817 2.997 4.285 1.00 0.00 ATOM 841 CG MET 170-5.432 1.460 3.174 1.00 0.00 ATOM 842 1HG MET 170-5.806 1.606 2.171 1.00 0.00 ATOM 843 2HG MET 170-6.112 0.822 3.717 1.00 0.00 ATOM 844 QG MET 170-5.959 1.214 2.944 1.00 0.00 ATOM 845 SD MET 170-3.830 0.635 3.076 1.00 0.00 ATOM 846 QE MET 170-4. 126-1. 035 4.394 1.00 0. 00 ATOM 847 CE MET 170-4.076-0.754 4.173 1.00 0.00 ATOM 848 1HE MET 170-4.455-1.595 3.611 1.00 0.00 ATOM 849 2HE MET 170-4.787-0.486 4.941 1.00 0.00 ATOM 850 3HE MET 170-3.135-1.022 4.630 1.00 0.00 ATOM 851 C MET 170-4.577 5.158 3.537 1.00 0.00 ATOM 852 O MET 170-4. 903 5.679 4.605 1.00 0.00

ATOM 853 N LEU 171-4.535 5.818 2.399 1.00 0.00 ATOM 854 H LEU 171-4.265 5.347 1. 582 1.00 0.00 ATOM 855 CA LEU 171-4.872 7.228 2.333 1.00 0.00 ATOM 856 HA LEU 171-5.059 7.564 3.343 1.00 0.00 ATOM 857 CB LEU 171-3.700 8.028 1.756 1.00 0.00 ATOM 858 1HB LEU 171-2.861 7.931 2.431 1.00 0.00 ATOM 859 2HB LEU 171-3. 986 9.068 1.716 1.00 0.00 ATOM 860 QB LEU 171-3.423 8.499 2.074 1.00 0.00 ATOM 861 CG LEU 171-3.239 7.603 0.362 1.00 0.00 ATOM 862 HG LEU 171-4.003 6.992-0.095 1.00 0.00 ATOM 863 QD1 LEU 171-2.970 9.108-0.721 1. 00 0.00 ATOM 864 QD2 LEU 171-1.658 6.592 0.463 1.00 0.00 ATOM 865 CD1 LEU 171-3.023 8.818-0.512 1.00 0.00 ATOM 866 1HD1 LEU 171-2.478 9.568 0.042 1.00 0.00 ATOM 867 2HD1 LEU 171-3.977 9.220-0.819 1.00 0.00 ATOM 868 3HD1 LEU 171-2.454 8.536-1.386 1.00 0.00 ATOM 869 CD2 LEU 171-1.963 6.785 0.443 1.00 0.00 ATOM 870 1HD2 LEU 171-1.240 7.179-0.257 1.00 0.00 ATOM 871 2HD2 LEU 171-2.176 5.756 0.200 1.00 0.00 ATOM 872 3HD2 LEU 171-1.559 6.843 1.445 1.00 0.00 ATOM 873 QQD LEU 171-2.314 7.850-0.129 1.00 0.00 ATOM 874 C LEU 171-6.130 7.446 1.508 1.00 0.00 ATOM 875 O LEU 171-6. 835 6.487 1.187 1.00 0.00 ATOM 876 N LEU 172-6.399 8.713 1.176 1.00 0.00 ATOM 877 H LEU 172-5.784 9.414 1.475 1.00 0.00 ATOM 878 CA LEU 172-7.574 9.102 0.389 1.00 0.00 ATOM 879 HA LEU 172-7.720 10.163 0.519 1.00 0.00 ATOM 880 CB LEU 172-7.348 8.818-1.102 1.00 0.00 ATOM 881 1HB LEU 172-8. 228 8.323-1.485 1.00 0.00 ATOM 882 2HB LEU 172-6.511 8.142-1.199 1.00 0.00 ATOM 883 QB LEU 172-7.369 8.232-1.342 1.00 0.00 ATOM 884 CG LEU 172-7.079 10.049-1.975 1.00 0.00 ATOM 885 HG LEU 172-6.704 9.725-2. 935 1.00 0.00 ATOM 886 QD1 LEU 172-8.668 11.010-2.270 1.00 0.00 ATOM 887 QD2 LEU 172-5.776 11.158-1.190 1.00 0.00 ATOM 888 CD1 LEU 172-8.364 10.826-2.213 1.00 0.00 ATOM 889 1HD1 LEU 172-8.471 11.028-3. 269 1.00 0.00 ATOM 890 2HD1 LEU 172-8.326 11.759-1.671 1.00 0.00 ATOM 891 3HD1 LEU 172-9.207 10.244-1.871 1.00 0.00 ATOM 892 CD2 LEU 172-6.027 10.946-1.339 1.00 0.00 ATOM 893 1HD2 LEU 172-5.730 10.536-0. 386 1.00 0.00 ATOM 894 2HD2 LEU 172-6.435 11.935-1.195 1.00 0.00 ATOM 895 3HD2 LEU 172-5.163 11.005-1.989 1.00 0.00 ATOM 896 QQD LEU 172-7.222 11.084-1.730 1.00 0.00 ATOM 897 C LEU 172-8.830 8.378 0.866 1.00 0.00 ATOM 898 O LEU 172-9.353 7.515 0.164 1.00 0.00 ATOM 899 N PRO 173-9.330 8.712 2.068 1.00 0.00 ATOM 900 CD PRO 173-8.777 9.729 2.980 1.00 0.00 ATOM 901 CA PRO 173-10.526 8.072 2.619 1.00 0.00 ATOM 902 HA PRO 173-10.345 7.028 2.842 1.00 0.00 ATOM 903 CB PRO 173-10.790 8.843 3.916 1.00 0.00 ATOM 904 1HB PRO 173-11.137 8.161 4.679 1.00 0.00 ATOM 905 2HB PRO 173-11.538 9.603 3.739 1.00 0.00 ATOM 906 QB PRO 173-11.337 8.882 4.209 1.00 0.00 ATOM 907 CG PRO 173-9.475 9.444 4.281 1.00 0.00 ATOM 908 1HG PRO 173-8.901 8.744 4.869 1.00 0.00 ATOM 909 2HG PRO 173-9.630 10.360 4.832 1.00 0.00 ATOM 910 QG PRO 173-9. 265 9.552 4.851 1.00 0.00 ATOM 911 1HD PRO 173-7.709 9.608 3.090 1.00 0.00 ATOM 912 2HD PRO 173-9.012 10.726 2.635 1.00 0.00 ATOM 913 QD PRO 173-8.360 10.167 2.863 1.00 0.00 ATOM 914 C PRO 173-11.716 8.185 1.675 1.00 0.00 ATOM 915 O PRO 173-11.941 9.222 1.051 1.00 0.00 ATOM 916 N CYS 174-12.464 7.106 1.567 1.00 0.00 ATOM 917 H CYS 174-12.229 6.307 2.087 1.00 0.00 ATOM 918 CA CYS 174-13.624 7.068 0.695 1.00 0.00 ATOM 919 HA CYS 174-13.676 8.008 0.167 1.00 0.00 ATOM 920 CB CYS 174-13.467 5.931-0. 313 1.00 0.00 ATOM 921 1HB CYS 174-13.137 5.045 0.209 1.00 0.00 ATOM 922 2HB CYS 174-12.720 6.210-1.041 1.00 0.00 ATOM 923 QB CYS 174-12.928 5.627-0.416 1.00 0.00 ATOM 924 SG CYS 174-14.983 5.503-1.221 1.00 0.00

ATOM 925 C CYS 174-14.889 6.894 1.521 1.00 0.00 ATOM 926 O CYS 174-15.948 7.419 1.181 1.00 0.00 ATOM 927 N GLY 175-14.760 6.172 2.621 1.00 0.00 ATOM 928 H GLY 175-13.880 5.795 2.847 1.00 0.00 ATOM 929 CA GLY 175-15.878 5.949 3.508 1.00 0.00 ATOM 930 1HA GLY 175-16.348 5.011 3.259 1.00 0.00 ATOM 931 2HA GLY 175-16.593 6.749 3.385 1.00 0.00 ATOM 932 QA GLY 175-16.470 5.880 3.322 1.00 0.00 ATOM 933 C GLY 175-15.422 5.908 4.945 1.00 0.00 ATOM 934 O GLY 175-14.298 6.304 5.247 1.00 0.00 ATOM 935 N ILE 176-16.278 5.418 5.831 1.00 0.00 ATOM 936 H ILE 176-17.155 5.107 5.530 1.00 0.00 ATOM 937 CA ILE 176-15.930 5.317 7.241 1.00 0.00 ATOM 938 HA ILE 176-15.543 6.274 7.563 1.00 0.00 ATOM 939 CB ILE 176-17.162 4.966 8.105 1.00 0.00 ATOM 940 HB ILE 176-17.282 3.893 8.096 1.00 0.00 ATOM 941 QG2 ILE 176-16.899 5.510 9.887 1.00 0.00 ATOM 942 CG2 ILE 176-16.948 5.406 9.546 1.00 0.00 ATOM 943 1HG2 ILE 176-15.994 5.041 9.896 1.00 0.00 ATOM 944 2HG2 ILE 176-17.738 5.004 10.164 1.00 0.00 ATOM 945 3HG2 ILE 176-16. 964 6.485 9.599 1.00 0.00 ATOM 946 CG1 ILE 176-18.428 5.615 7.535 1.00 0.00 ATOM 947 1HG1 ILE 176-18.621 5.214 6.551 1.00 0.00 ATOM 948 2HG1 ILE 176-18.276 6.682 7.461 1.00 0.00 ATOM 949 QG1 ILE 176-18.448 5.948 7.006 1.00 0.00 ATOM 950 QD1 ILE 176-19.953 5.326 8.585 1.00 0.00 ATOM 951 CD1 ILE 176-19.661 5.382 8.383 1.00 0.00 ATOM 952 1HD1 ILE 176-20.258 6.281 8.405 1.00 0.00 ATOM 953 2HD1 ILE 176-19.360 5.124 9.388 1.00 0.00 ATOM 954 3HD1 ILE 176-20.240 4.574 7.962 1.00 0.00 ATOM 955 C ILE 176-14.849 4.251 7.436 1.00 0.00 ATOM 956 O ILE 176-14.007 4.353 8.328 1.00 0.00 ATOM 957 N ASP 177-14.888 3.232 6.584 1.00 0.00 ATOM 958 H ASP 177-15.587 3.215 5.899 1.00 0.00 ATOM 959 CA ASP 177-13.927 2.134 6.633 1.00 0.00 ATOM 960 HA ASP 177-13. 184 2.366 7.380 1.00 0.00 ATOM 961 CB ASP 177-14.643 0.832 7.012 1.00 0.00 ATOM 962 1HB ASP 177-15.299 1.019 7.849 1.00 0.00 ATOM 963 2HB ASP 177-13.907 0.094 7.295 1.00 0.00 ATOM 964 QB ASP 177-14. 603 0.556 7.572 1.00 0.00 ATOM 965 CG ASP 177-15.469 0.273 5.867 1.00 0.00 ATOM 966 OD1 ASP 177-16.378 0.978 5.383 1.00 0.00 ATOM 967 OD2 ASP 177-15. 200-0. 866 5.432 1.00 0.00 ATOM 968 C ASP 177-13.245 1.946 5.278 1.00 0.00 ATOM 969 O ASP 177-12.327 1.134 5.135 1.00 0.00 ATOM 970 N LYS+ 178-13.726 2.674 4.279 1.00 0.00 ATOM 971 H LYS+ 178-14.471 3.282 4.451 1.00 0.00 ATOM 972 CA LYS+ 178-13.196 2.564 2.925 1.00 0.00 ATOM 973 HA LYS+ 178-12.679 1.620 2.849 1.00 0.00 ATOM 974 CB LYS+ 178-14.346 2.577 1.918 1.00 0.00 ATOM 975 1HB LYS+ 178-13.957 2.332 0.942 1.00 0.00 ATOM 976 2HB LYS+ 178-14.769 3.571 1.887 1.00 0.00 ATOM 977 QB LYS+ 178-14.363 2.951 1.415 1.00 0.00 ATOM 978 CG LYS+ 178-15.462 1.594 2.252 1.00 0.00 ATOM 979 1HG LYS+ 178-16.394 2.135 2.328 1.00 0.00 ATOM 980 2HG LYS+ 178-15.240 1.121 3.198 1.00 0.00 ATOM 981 QG LYS+ 178-15.817 1.628 2.763 1.00 0.00 ATOM 982 CD LYS+ 178-15.601 0.516 1.184 1.00 0.00 ATOM 983 1HD LYS+ 178-14.743 0.562 0.527 1.00 0.00 ATOM 984 2HD LYS+ 178-16. 499 0.702 0.612 1.00 0.00 ATOM 985 QD LYS+ 178-15.621 0.632 0.570 1.00 0.00 ATOM 986 CE LYS+ 178-15.684-0. 880 1.791 1.00 0.00 ATOM 987 1HE LYS+ 178-14.680-1. 234 1.984 1. 00 0. 00 ATOM 988 2HE LYS+ 178-16.164-1. 539 1.081 1.00 0.00 ATOM 989 QE LYS+ 178-15.422-1.387 1.533 1.00 0.00 ATOM 990 NZ LYS+ 178-16.457-0. 894 3.066 1.00 0.00 ATOM 991 1HZ LYS+ 178-15.808-0.814 3.887 1.00 0.00 ATOM 992 2HZ LYS+ 178-16.989-1. 779 3.153 1.00 0.00 ATOM 993 3HZ LYS+ 178-17.121-0.099 3.096 1.00 0.00 ATOM 994 QZ LYS+ 178-16.639-0.898 3.379 1.00 0.00 ATOM 995 C LYS+ 178-12.202 3.666 2.601 1.00 0.00 ATOM 996 O LYS+ 178-12.305 4.785 3.097 1.00 0.00

ATOM 997 N PHE 179-11. 242 3.332 1.747 1.00 0.00 ATOM 998 H PHE 179-11.227 2.423 1.376 1.00 0.00 ATOM 999 CA PHE 179-10.213 4.267 1.332 1.00 0.00 ATOM 1000 HA PHE 179-10.537 5.266 1.583 1.00 0. 00 ATOM 1001 CB PHE 179-8.887 3.971 2.035 1.00 0.00 ATOM 1002 1HB PHE 179-8. 160 4.664 1.675 1.00 0.00 ATOM 1003 2HB PHE 179-8.561 2.978 1.781 1.00 0.00 ATOM 1004 QB PHE 179-8.360 3.821 1.728 1.00 0.00 ATOM 1005 QD PHE 179-8.941 4.093 3.702 1.00 0.00 ATOM 1006 QE PHE 179-9.023 4.279 6.153 1.00 0.00 ATOM 1007 QR PHE 179-8.999 4.224 5.418 1.00 0. 00 ATOM 1008 CG PHE 179-8.936 4.082 3.535 1.00 0.00 ATOM 1009 CD1 PHE 179-9.434 3.043 4.307 1.00 0.00 ATOM 1010 1HD PHE 179-9.791 2.146 3.822 1.00 0.00 ATOM 1011 CE1 PHE 179-9.481 3.145 5.684 1.00 0.00 ATOM 1012 1HE PHE 179-9.875 2.329 6.273 1.00 0.00 ATOM 1013 CZ PHE 179-9. 027 4.291 6.305 1.00 0.00 ATOM 1014 HZ PHE 179-9.065 4.374 7.382 1.00 0.00 ATOM 1015 CE2 PHE 179-8.527 5.332 5.548 1.00 0.00 ATOM 1016 2HE PHE 179-8.172 6.230 6.032 1.00 0.00 ATOM 1017 CD2 PHE 179-8.483 5.225 4.171 1.00 0.00 ATOM 1018 2HD PHE 179-8.091 6.041 3.581 1.00 0.00 ATOM 1019 C PHE 179-9.994 4.170-0.163 1.00 0.00 ATOM 1020 O PHE 179-10.704 3.442-0.859 1.00 0.00 ATOM 1021 N ARG+ 180-8.993 4.889-0.644 1.00 0.00 ATOM 1022 H ARG+ 180-8.463 5.439-0.023 1.00 0.00 ATOM 1023 CA ARG+ 180-8.644 4.881-2.058 1.00 0.00 ATOM 1024 HA ARG+ 180-9.068 3.992-2.505 1.00 0.00 ATOM 1025 CB ARG+ 180-9.213 6. 116-2.770 1.00 0.00 ATOM 1026 1HB ARG+ 180-9.014 6.023-3.827 1.00 0. 00 ATOM 1027 2HB ARG+ 180-8.706 6.993-2.401 1.00 0.00 ATOM 1028 QB ARG+ 180-8.860 6.508-3.114 1.00 0.00 ATOM 1029 CG ARG+ 180-10.709 6.311-2.579 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.867 7.076-1.832 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.140 5.380-2.239 1.00 0.00 ATOM 1032 QG ARG+ 180-11.003 6.228-2.035 1.00 0.00 ATOM 1033 CD ARG+ 180-11.393 6.727-3.872 1.00 0.00 ATOM 1034 1HD ARG+ 180-11.956 5.885-4.251 1.00 0.00 ATOM. 1035 2HD ARG+ 180-10.635 7.003-4.591 1.00 0.00 ATOM 1036 QD ARG+ 180-11.295 6.444-4.421 1.00 0.00 ATOM 1037 NE ARG+ 180-12.299 7.860-3.678 1.00 0. 00 ATOM 1038 HE ARG+ 180-12.296 8.294-2.795 1.00 0.00 ATOM 1039 CZ ARG+ 180-13.117 8.327-4.623 1.00 0.00 ATOM 1040 NH1 ARG+ 180-13.120 7.776-5.832 1.00 0.00 ATOM 1041 IHH1 ARG+ 180-12.506 7.009-6.038 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.727 8.125-6.546 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.116 7.567-6.292 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.917 9.355-4.361 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-13.909 9.780-3.454 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-14.530 9.709-5.069 1.00 0.00 ATOM 1047 QH2 ARG+ 180-14.219 9.744-4.261 1.00 0.00 ATOM 1048 C ARG+ 180-7.128 4.849-2.237 1.00 0.00 ATOM 1049 O ARG+ 180-6.630 4.556-3.313 1.00 0.00 ATOM 1050 N GLY 181-6.389 5.165-1.187 1.00 0.00 ATOM 1051 H GLY 181-6.820 5.399-0.337 1.00 0.00 ATOM 1052 CA GLY 181-4.944 5.180-1.301 1.00 0.00 ATOM 1053 1HA GLY 181-4. 579 6.134-0.951 1.00 0.00 ATOM 1054 2HA GLY 181-4.682 5.072-2.343 1.00 0.00 ATOM 1055 QA GLY 181-4.630 5.603-1.647 1.00 0.00 ATOM 1056 C GLY 181-4.263 4.082-0.519 1.00 0.00 ATOM 1057 0 GLY 181-4.807 3.574 0.460 1.00 0.00 ATOM 1058 N VAL 182-3.060 3.726-0.960 1.00 0.00 ATOM 1059 H VAL 182-2.693 4.186-1.737 1.00 0.00 ATOM 1060 CA VAL 182-2.257 2.690-0.324 1.00 0.00 ATOM 1061 HA VAL 182-2.547 2.624 0.718 1.00 0.00 ATOM 1062 CB VAL 182-2. 454 1.300-0.988 1.00 0.00 ATOM 1063 HB VAL 182-1.678 1.176-1.731 1.00 0.00 ATOM 1064 QG1 VAL 182-2.258-0.070 0.282 1.00 0.00 ATOM 1065 QG2 VAL 182-4.120 1.156-1.853 1.00 0.00 ATOM 1066 CG1 VAL 182-2.295 0.193 0.038 1.00 0.00 ATOM 1067 1HG1 VAL 182-2.434 0.598 1.030 1.00 0.00 ATOM 1068 2HG1 VAL 182-1.306-0.234-0.042 1.00 0.00

ATOM 1069 3HG1 VAL 182-3. 034-0. 573-0. 144 1.00 0.00 ATOM 1070 CG2 VAL 182-3. 802 1.184-1.688 1.00 0.00 ATOM 1071 1HG2 VAL 182-4. 556 1.689-1.103 1.00 0.00 ATOM 1072 2HG2 VAL 182-4. 065 0.142-1.792 1.00 0.00 ATOM 1073 3HG2 VAL 182-3.740 1.639-2.666 1.00 0.00 ATOM 1074 QQG VAL 182-3. 189 0.543-0.786 1.00 0.00 ATOM 1075 C VAL 182-0.771 3.051-0.408 1.00 0.00 ATOM 1076 O VAL 182-0.239 3.264-1.497 1.00 0.00 ATOM 1077 N GLU 183-0.114 3.108 0.742 1.00 0.00 ATOM 1078 H GLU 183-0.604 2.922 1.576 1.00 0.00 ATOM 1079 CA GLU 183 1.309 3.425 0.819 1.00 0.00 ATOM 1080 HA GLU 183 1.712 3.411-0.185 1.00 0.00 ATOM 1081 CB GLU 183 1.523 4.811 1.435 1.00 0.00 ATOM 1082 1HB GLU 183 1.547 5.544 0.642 1.00 0.00 ATOM 1083 2HB GLU 183 2.474 4.820 1.947 1.00 0.00 ATOM 1084 QB GLU 183 2.011 5.182 1.295 1.00 0. 00 ATOM 1085 CG GLU 183 0.451 5.225 2.429 1.00 0.00 ATOM 1086 1HG GLU 183 0.486 4.556 3.276 1.00 0.00 ATOM 1087 2HG GLU 183-0.514 5. 153 1.952 1.00 0.00 ATOM 1088 QG GLU 183-0. 014 4.854 2.614 1.00 0.00 ATOM 1089 CD GLU 183 0.641 6.640 2.921 1.00 0.00 ATOM 1090 OE1 GLU 183-0.328 7.219 3.450 1.00 0.00 ATOM 1091 OE2 GLU 183 1.759 7.174 2.766 1.00 0.00 ATOM 1092 C GLU 183 2.013 2.361 1.655 1.00 0.00 ATOM 1093 O GLU 183 2.010 2.415 2.879 1.00 0.00 ATOM 1094 N PHE 184 2.567 1.365 0.993 1.00 0.00 ATOM 1095 H PHE 184 2.505 1.351 0.020 1.00 0.00 ATOM 1096 CA PHE 184 3.211 0.258 1.685 1.00 0.00 ATOM 1097 HA PHE 184 3.092 0.427 2.742 1.00 0.00 ATOM 1098 CB PHE 184 2.518-1.060 1.321 1.00 0.00 ATOM 1099 1HB PHE 184 1.634-1. 176 1.931 1.00 0.00 ATOM 1100 2HB PHE 184 3.193-1.878 1.531 1.00 0.00 ATOM 1101 QB PHE 184 2.414-1.527 1.731 1.00 0.00 ATOM 1102 QD PHE 184 2.056-1.180-0.296 1.00 0.00 ATOM 1103 QE PHE 184 1.373-1. 399-2.647 1.00 0.00 ATOM 1104 QR PHE 184 1.577-1.335-1.941 1.00 0.00 ATOM 1105 CG PHE 184 2.105-1.168-0.131 1.00 0.00 ATOM 1106 CD1 PHE 184 1.061-0.407-0.641 1.00 0.00 ATOM 1107 1HD PHE 184 0.546 0.287 0.006 1.00 0.00 ATOM 1108 CE1 PHE 184 0.675-0.529-1.963 1.00 0.00 ATOM 1109 1HE PHE 184-0.139 0.070-2.346 1.00 0.00 ATOM 1110 CZ PHE 184 1.330-1.414-2.792 1.00 0.00 ATOM 1111 HZ PHE 184 1.025-1.517-3.822 1.00 0.00 ATOM 1112 CE2 PHE 184 2.370-2.173-2.300 1.00 0.00 ATOM 1113 2HE PHE 184 2.885-2.867-2.948 1.00 0.00 ATOM 1114 CD2 PHE 184 2.750-2.050-0.979 1.00 0.00 ATOM 1115 2HD PHE 184 3.566-2.646-0.599 1.00 0.00 ATOM 1116 C PHE 184 4.695 0.140 1.377 1.00 0.00 ATOM 1117 O PHE 184 5.125 0.317 0.243 1.00 0.00 ATOM 1118 N VAL 185 5.467-0.190 2.400 1.00 0.00 ATOM 1119 H VAL 185 5.056-0.333 3.280 1.00 0.00 ATOM 1120 CA VAL 185 6.901-0.367 2.258 1.00 0.00 ATOM 1121 HA VAL 185 7.187-0.045 1.266 1.00 0.00 ATOM 1122 CB VAL 185 7.682 0.470 3.299 1.00 0.00 ATOM 1123 HB VAL 185 7.872-0. 154 4.164 1.00 0.00 ATOM 1124 QG1 VAL 185 9.331 1.032 2.609 1.00 0.00 ATOM 1125 QG2 VAL 185 6.685 1.960 3.865 1.00 0.00 ATOM 1126 CG1 VAL 185 9.015 0.923 2.740 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.224 0.389 1.825 1.00 0. 00 ATOM 1128 2HG1 VAL 185 9.792 0.723 3.462 1.00 0.00 ATOM 1129 3HG1 VAL 185 8.977 1.984 2.538 1.00 0.00 ATOM 1130 CG2 VAL 185 6.876 1.675 3.755 1.00 0.00 ATOM 1131 1HG2 VAL 185 7.081 2.514 3.107 1.00 0.00 ATOM 1132 2HG2 VAL 185 7.152 1.928 4.769 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.823 1.440 3.719 1.00 0.00 ATOM 1134 QQG VAL 185 8.008 1.496 3.237 1.00 0.00 ATOM 1135 C VAL 185 7.248-1.848 2.418 1.00 0.00 ATOM 1136 O VAL 185 7.274-2.374 3.528 1.00 0.00 ATOM 1137 N CYS 186 7.497-2.527 1.306 1.00 0.00 ATOM 1138 H CYS 186 7.452-2.065 0.438 1.00 0.00 ATOM 1139 CA CYS 186 7.828-3.946 1.347 1. 00 0. 00 ATOM 1140 HA CYS 186 7.631-4.294 2.353 1.00 0.00

ATOM 1141 CB CYS 186 6.954-4.745 0.371 1.00 0.00 ATOM 1142 1HB CYS 186 5.955-4.817 0.778 1.00 0.00 ATOM 1143 2HB CYS 186 7.362-5.739 0.272 1.00 0.00 ATOM 1144 QB CYS 186 6.659-5.278 0.525 1.00 0.00 ATOM 1145 SG CYS 186 6.816-4.051-1.305 1.00 0.00 ATOM 1146 C CYS 186 9.307-4.160 1.048 1.00 0.00 ATOM 1147 O CYS 186 9.838-3.611 0.091 1.00 0.00 ATOM 1148 N CYS 187 9.976-4.953 1.873 1.00 0.00 ATOM 1149 H CYS 187 9.505-5.369 2.627 1.00 0.00 ATOM 1150 CA CYS 187 11.403-5.212 1.686 1.00 0. 00 ATOM 1151 HA CYS 187 11.825-4.367 1.166 1.00 0.00 ATOM 1152 CB CYS 187 12.110-5.370 3.034 1.00 0.00 ATOM 1153 1HB CYS 187 12.914-6.085 2.925 1.00 0.00 ATOM 1154 2HB CYS 187 11.404-5.744 3.761 1.00 0.00 ATOM 1155 QB CYS 187 12.159-5.915 3.343 1.00 0.00 ATOM 1156 SG CYS 187 12.821-3.833 3.698 1.00 0. 00 ATOM 1157 C CYS 187 11.638-6.459 0.862 1.00 0.00 ATOM 1158 O CYS 187 10.922-7.443 1.008 1.00 0.00 ATOM 1159 N PRO 188 12.654-6.431-0.018 1.00 0.00 ATOM 1160 CD PRO 188 13.550-5.283-0.254 1.00 0.00 ATOM 1161 CA PRO 188 12.985-7.576-0.861 1.00 0.00 ATOM 1162 HA PRO 188 12.137-7.883-1.458 1.00 0. 00 ATOM 1163 CB PRO 188 14.101-7.062-1.777 1.00 0.00 ATOM 1164 1HB PRO 188 13.687-6.816-2.744 1.00 0. 00 ATOM 1165 2HB PRO 188 14.853-7.830-1.891 1.00 0.00 ATOM 1166 QB PRO 188 14.270-7.323-2.317 1.00 0.00 ATOM 1167 CG PRO 188 14. 656-5.854-1.100 1.00 0.00 ATOM 1168 1HG PRO 188 14. 969-5.132-1.841 1.00 0.00 ATOM 1169 2HG PRO 188 15.491-6.138-0.479 1.00 0.00 ATOM 1170 QG PRO 188 15.230-5.635-1.160 1.00 0.00 ATOM 1171 1HD PRO 188 13.036-4.495-0.787 1.00 0.00 ATOM 1172 2HD PRO 188 13.947-4.907 0.677 1.00 0.00 ATOM 1173 QD PRO 188 13.492-4.701-0.055 1.00 0.00 ATOM 1174 C PRO 188 13.466-8.762-0.035 1.00 0.00 ATOM 1175 O PRO 188 14.445-8.651 0.718 1.00 0.00 ATOM 1176 N LEU 189 12.767-9.879-0.185 1.00 0.00 ATOM 1177 H LEU 189 12.004-9.880-0.803 1.00 0.00 ATOM 1178 CA LEU 189 13.090-11.105 0.522 1.00 0.00 ATOM 1179 HA LEU 189 13.701-10.850 1.375 1.00 0.00 ATOM 1180 CB LEU 189 11.812-11.799 1.001 1.00 0.00 ATOM 1181 1HB LEU 189 11.234-12.075 0.131 1.00 0.00 ATOM 1182 2HB LEU 189 11.239-11.093 1.584 1.00 0. 00 ATOM 1183 QB LEU 189 11.237-11.584 0.858 1.00 0. 00 ATOM 1184 CG LEU 189 12.032-13.057 1.845 1.00 0.00 ATOM 1185 HG LEU 189 12.983-13.498 1.577 1.00 0.00 ATOM 1186 QD1 LEU 189 12.084-12.629 3.674 1.00 0.00 ATOM 1187 QD2 LEU 189 10.685-14.322 1.503 1.00 0.00 ATOM 1188 CD1 LEU 189 12.074-12.710 3.324 1.00 0.00 ATOM 1189 1HD1 LEU 189 11.366-11.921 3.529 1.00 0.00 ATOM 1190 2HD1 LEU 189 13.068-12.381 3.587 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.819-13.583 3.904 1. 00 0. 00 ATOM 1192 CD2 LEU 189 10.942-14.080 1.568 1.00 0. 00 ATOM 1193 1HD2 LEU 189 10.122-13.602 1.054 1.00 0.00 ATOM 1194 2HD2 LEU 189 10.591-14.492 2.502 1.00 0.00 ATOM 1195 3HD2 LEU 189 11.342-14.871 0.952 1.00 0.00 ATOM 1196 QQD LEU 189 11.385-13.475 2.588 1.00 0.00 ATOM 1197 C LEU 189 13.875-12.034-0.393 1.00 0.00 ATOM 1198 OT1 LEU 189 14.900-12.582 0.060 1.00 0.00 ATOM 1199 OT2 LEU 189 13.463-12.191-1.563 1.00 0.00 TER ENDMDL MODEL 5 ATOM 1 N SER 124 14.104 16.201 3.246 1.00 0. 00 ATOM 2 CA SER 124 14.415 14.750 3.301 1.00 0.00 ATOM 3 HA SER 124 15.075 14.501 2.483 1.00 0.00 ATOM 4 CB SER 124 15.115 14.467 4. 629 1.00 0.00 ATOM 5 1HB SER 124 15.976 13.839 4.455 1.00 0.00 ATOM 6 2HB SER 124 14.428 13.963 5.294 1.00 0. 00 ATOM 7 QB SER 124 15.202 13.901 4.874 1.00 0.00 ATOM 8 OG SER 124 15.543 15.678 5.238 1.00 0.00 ATOM 9 HG SER 124 15.908 15.488 6. 112 1.00 0.00 ATOM 10 C SER 124 13.138 13.937 3.184 1.00 0.00

ATOM 11 O SER 124 12.970 12.906 3.835 1.00 0.00 ATOM 12 1HT SER 124 14.537 16.631 2.407 1.00 0.00 ATOM 13 2HT SER 124 14.473 16.673 4.097 1.00 0.00 ATOM 14 3HT SER 124 13.069 16.345 3.204 1.00 0.00 ATOM 15 N ASP 125 12.238 14.440 2.363 1.00 0.00 ATOM 16 H ASP 125 12.439 15.279 1.896 1.00 0.00 ATOM 17 CA ASP 125 10.946 13.830 2.139 1.00 0.00 ATOM 18 HA ASP 125 10.646 13.330 3.047 1.00 0.00 ATOM 19 CB ASP 125 9.931 14.928 1.812 1.00 0.00 ATOM 20 1HB ASP 125 8.958 14.633 2.177 1.00 0.00 ATOM 21 2HB ASP 125 9.885 15.063 0.742 1.00 0.00 ATOM 22 QB ASP 125 9.421 14.848 1.459 1.00 0.00 ATOM 23 CG ASP 125 10.301 16.258 2.450 1.00 0.00 ATOM 24 OD1 ASP 125 9.577 16.698 3.360 1.00 0.00 ATOM 25 OD2 ASP 125 11.338 16.849 2.055 1.00 0.00 ATOM 26 C ASP 125 11.020 12.816 1.007 1.00 0.00 ATOM 27 O ASP 125 11.375 13.154-0.122 1.00 0. 00 ATOM 28 N ALA 126 10.692 11.571 1.315 1.00 0.00 ATOM 29 H ALA 126 10.420 11.360 2.233 1.00 0.00 ATOM 30 CA ALA 126 10.726 10.508 0.322 1.00 0.00 ATOM 31 HA ALA 126 10.902 10.960-0.643 1.00 0.00 ATOM 32 QB ALA 126 12. 138 9.316 0.680 1.00 0.00 ATOM 33 CB ALA 126 11.869 9.545 0.612 1.00 0.00 ATOM 34 1HB ALA 126 12.488 9.946 1.400 1.00 0.00 ATOM 35 2HB ALA 126 12.462 9.411-0.280 1.00 0.00 ATOM 36 3HB ALA 126 11.465 8.591 0.922 1.00 0.00 ATOM 37 C ALA 126 9.403 9.758 0.287 1.00 0.00 ATOM 38 O ALA 126 9.053 9.053 1.231 1.00 0.00 ATOM 39 N LEU 127 8.672 9.911-0.808 1.00 0.00 ATOM 40 H LEU 127 9.004 10.484-1.527 1.00 0.00 ATOM 41 CA LEU 127 7.387 9.244-0.970 1.00 0.00 ATOM 42 HA LEU 127 7.006 9.013 0.013 1.00 0.00 ATOM 43 CB LEU 127 6.401 10.167-1.688 1.00 0.00 ATOM 44 1HB LEU 127 6.503 10.000-2.750 1.00 0.00 ATOM 45 2HB LEU 127 6.673 11.189-1.473 1.00 0.00 ATOM 46 QB LEU 127 6.588 10.595-2.112 1.00 0.00 ATOM 47 CG LEU 127 4.931 9.969-1.313 1.00 0.00 ATOM 48 HG LEU 127 4.779 8.945-1.002 1.00 0.00 ATOM 49 QDl LEU 127 4.455 11.087 0.120 1.00 0.00 ATOM 50 QD2 LEU 127 3.818 10.296-2.794 1.00 0.00 ATOM 51 CD1 LEU 127 4.548 10.873-0.153 1.00 0.00 ATOM 52 1HD1 LEU 127 4.578 10.309 0.767 1.00 0.00 ATOM 53 2HD1 LEU 127 3.548 11.252-0.310 1.00 0.00 ATOM 54 3HD1 LEU 127 5.241 11.698-0.095 1.00 0.00 ATOM 55 CD2 LEU 127 4.033 10.234-2.511 1.00 0. 00 ATOM 56 1HD2 LEU 127 3.192 10.839-2.203 1.00 0.00 ATOM 57 2HD2 LEU 127 3.673 9.294-2.905 1.00 0.00 ATOM 58 3HD2 LEU 127 4.591 10.754-3.274 1.00 0.00 ATOM 59 QQD LEU 127 4.137 10.691-1.337 1.00 0.00 ATOM 60 C LEU 127 7.553 7.948-1.758 1.00 0.00 ATOM 61 O LEU 127 6.578 7.357-2.221 1.00 0.00 ATOM 62 N LEU 128 8.795 7.517-1.914 1.00 0.00 ATOM 63 H LEU 128 9.529 8.031-1.527 1.00 0.00 ATOM 64 CA LEU 128 9.092 6.301-2.651 1.00 0.00 ATOM 65 HA LEU 128 8.164 5.780-2.822 1.00 0. 00 ATOM 66 CB LEU 128 9.732 6.665-4.002 1.00 0.00 ATOM 67 1HB LEU 128 10.805 6.667-3.870 1.00 0.00 ATOM 68 2HB LEU 128 9.423 7.668-4.256 1.00 0.00 ATOM 69 QB LEU 128 10.114 7.168-4.063 1.00 0.00 ATOM 70 CG LEU 128 9.401 5.750-5.198 1.00 0.00 ATOM 71 HG LEU 128 8.840 6.323-5.927 1.00 0.00 ATOM 72 QD1 LEU 128 10.976 5.155-6.030 1.00 0.00 ATOM 73 QD2 LEU 128 8.337 4.286-4.690 1.00 0.00 ATOM 74 CD1 LEU 128 10.675 5.269-5.870 1.00 0.00 ATOM 75 1HD1 LEU 128 10.690 5.608-6.895 1.00 0.00 ATOM 76 2HD1 LEU 128 10.707 4.189-5.848 1.00 0.00 ATOM 77 3HD1 LEU 128 11.532 5.666-5.347 1.00 0.00 ATOM 78 CD2 LEU 128 8.542 4.566-4.787 1.00 0.00 ATOM 79 1HD2 LEU 128 8.670 3.765-5.500 1.00 0.00 ATOM 80 2HD2 LEU 128 7.504 4.865-4.764 1.00 0.00 ATOM 81 3HD2 LEU 128 8.839 4.226-3.806 1.00 0.00 ATOM 82 QQD LEU 128 9.657 4.720-5.360 1.00 0.00

ATOM 83 C LEU 128 10.019 5.413-1.817 1.00 0.00 ATOM 84 O LEU 128 10.039 5.519-0.592 1.00 0.00 ATOM 85 N VAL 129 10.771 4.543-2.484 1.00 0.00 ATOM 86 H VAL 129 10.698 4.514-3.460 1.00 0.00 ATOM 87 CA VAL 129 11.698 3.623-1.819 1.00 0.00 ATOM 88 HA VAL 129 11.117 2.934-1.226 1.00 0.00 ATOM 89 CB VAL 129 12.496 2.810-2.866 1.00 0.00 ATOM 90 HB VAL 129 13.124 3.497-3.415 1.00 0.00 ATOM 91 QG1 VAL 129 13.611 1.540-2.040 1.00 0.00 ATOM 92 QG2 VAL 129 11.336 1.975-4.088 1.00 0.00 ATOM 93 CG1 VAL 129 13.396 1.782-2.199 1.00 0.00 ATOM 94 1HG1 VAL 129 12.843 1.258-1.433 1.00 0.00 ATOM 95 2HG1 VAL 129 14.243 2.284-1.750 1.00 0.00 ATOM 96 3HG1 VAL 129 13.747 1.077-2.937 1.00 0.00 ATOM 97 CG2 VAL 129 11.557 2.134-3.853 1.00 0.00 ATOM 98 1HG2 VAL 129 11.802 2.452-4.856 1.00 0.00 ATOM 99 2HG2 VAL 129 10.537 2.408-3.627 1.00 0.00 ATOM 100 3HG2 VAL 129 11.669 1.063-3.779 1.00 0.00 ATOM 101 QQG VAL 129 12.473 1.757-3.064 1.00 0.00 ATOM 102 C VAL 129 12.683 4.360-0.904 1.00 0.00 ATOM 103 O VAL 129 13.488 5.165-1.370 1.00 0.00 ATOM 104 N PRO 130 12.620 4.091 0.416 1.00 0.00 ATOM 105 CD PRO 130 11.674 3.156 1.049 1.00 0.00 ATOM 106 CA PRO 130 13.500 4.721 1.395 1.00 0.00 ATOM 107 HA PRO 130 13.659 5.757 1.167 1.00 0.00 ATOM 108 CB PRO 130 12.711 4.605 2.701 1.00 0.00 ATOM 109 1HB PRO 130 12.145 5.511 2.860 1.00 0.00 ATOM 110 2HB PRO 130 13.398 4.460 3.523 1.00 0.00 ATOM 111 QB PRO 130 12.771 4.986 3.191 1.00 0.00 ATOM 112 CG PRO 130 11.808 3.422 2.532 1.00 0.00 ATOM 113 1HG PRO 130 10.839 3.644 2.957 1.00 0.00 ATOM 114 2HG PRO 130 12.239 2.563 3.023 1.00 0.00 ATOM 115 QG PRO 130 11.539 3.104 2.990 1.00 0.00 ATOM 116 1HD PRO 130 10.664 3.357 0.725 1.00 0.00 ATOM 117 2HD PRO 130 11.943 2.134 0.825 1.00 0.00 ATOM 118 QD PRO 130 11.303 2.746 0.775 1.00 0.00 ATOM 119 C PRO 130 14.859 4.028 1.507 1.00 0.00 ATOM 120 O PRO 130 15.782 4.320 0.751 1.00 0.00 ATOM 121 N ASP 131 14.968 3.126 2.470 1.00 0.00 ATOM 122 H ASP 131 14.194 2.961 3.038 1.00 0.00 ATOM 123 CA ASP 131 16.207 2.390 2.715 1.00 0.00 ATOM 124 HA ASP 131 17.031 3.050 2.486 1.00 0.00 ATOM 125 CB ASP 131 16.289 1.991 4.194 1.00 0.00 ATOM 126 1HB ASP 131 15.513 1.273 4.411 1.00 0.00 ATOM 127 2HB ASP 131 16.142 2.868 4.805 1.00 0.00 ATOM 128 QB ASP 131 15.827 2.071 4.608 1.00 0.00 ATOM 129 CG ASP 131 17.622 1.380 4.559 1.00 0.00 ATOM 130 OD1 ASP 131 18.664 1.953 4.194 1.00 0.00 ATOM 131 OD2 ASP 131 17.629 0.310 5.198 1.00 0.00 ATOM 132 C ASP 131 16.311 1.151 1.818 1.00 0.00 ATOM 133 O ASP 131 16.658 1.252 0.644 1.00 0.00 ATOM 134 N LYS+ 132 16.017-0.021 2.375 1.00 0.00 ATOM 135 H LYS+ 132 15.756-0.049 3.319 1.00 0.00 ATOM 136 CA LYS+ 132 16.094-1.266 1.613 1.00 0.00 ATOM 137 HA LYS+ 132 16.598-1.048 0.681 1.00 0.00 ATOM 138 CB LYS+ 132 16.902-2.318 2.378 1.00 0.00 ATOM 139 1HB LYS+ 132 16.966-3.213 1.775 1.00 0.00 ATOM 140 2HB LYS+ 132 16.386-2.552 3.297 1.00 0.00 ATOM 141 QB LYS+ 132 16.676-2.882 2.536 1.00 0.00 ATOM 142 CG LYS+ 132 18.316-1.872 2.721 1.00 0.00 ATOM 143 1HG LYS+ 132 18.318-0.799 2.858 1.00 0.00 ATOM 144 2HG LYS+ 132 18.974-2.135 1.907 1.00 0.00 ATOM 145 QG LYS+ 132 18.646-1.467 2.382 1.00 0.00 ATOM 146 CD LYS+ 132 18.816-2.534 3.997 1.00 0.00 ATOM 147 1HD LYS+ 132 19.035-3.572 3.790 1.00 0.00 ATOM 148 2HD LYS+ 132 18.043-2.472 4.749 1.00 0.00 ATOM 149 QD LYS+ 132 18.539-3.022 4.269 1.00 0.00 ATOM 150 CE LYS+ 132 20.074-1.858 4.527 1.00 0.00 ATOM 151 1HE LYS+ 132 20.935-2.295 4.042 1.00 0.00 ATOM 152 2HE LYS+ 132 20.137-2.029 5.592 1.00 0.00 ATOM 153 QE LYS+ 132 20.536-2.162 4.817 1.00 0.00 ATOM 154 NZ LYS+ 132 20.069-0.390 4.275 1.00 0.00

ATOM 155 1HZ LYS+ 132 20.129-0.194 3.258 1.00 0.00 ATOM 156 2HZ LYS+ 132 20.869 0.066 4.753 1.00 0.00 ATOM 157 3HZ LYS+ 132 19.177 0.037 4.642 1.00 0.00 ATOM 158 QZ LYS+ 132 20.058-0.030 4.217 1.00 0.00 ATOM 159 C LYS+ 132 14.705-1.811 1.299 1.00 0.00 ATOM 160 O LYS+ 132 14.560-2.795 0.576 1.00 0.00 ATOM 161 N CYS 133 13.684-1.167 1.840 1.00 0.00 ATOM 162 H CYS 133 13.857-0.387 2.401 1.00 0.00 ATOM 163 CA CYS 133 12.311-1.590 1.603 1.00 0.00 ATOM 164 HA CYS 133 12.326-2.639 1.347 1.00 0.00 ATOM 165 CB CYS 133 11.454-1.388 2.854 1.00 0.00 ATOM 166 1HB CYS 133 10.443-1.157 2.548 1.00 0.00 ATOM 167 2HB CYS 133 11.845-0.556 3.414 1.00 0.00 ATOM 168 QB CYS 133 11.144-0.856 2.981 1.00 0.00 ATOM 169 SG CYS 133 11.373-2.820 3.981 1.00 0.00 ATOM 170 C CYS 133 11.719-0.804 0.442 1.00 0.00 ATOM 171 O CYS 133 12.114 0.326 0.188 1.00 0.00 ATOM 172 N LYS+ 134 10.765-1.402-0.249 1.00 0.00 ATOM 173 H LYS+ 134 10.479-2.303 0.012 1.00 0.00 ATOM 174 CA LYS+ 134 10.115-0.756-1.378 1.00 0.00 ATOM 175 HA LYS+ 134 10.791-0.013-1.776 1.00 0.00 ATOM 176 CB LYS+ 134 9.795-1.787-2.465 1.00 0.00 ATOM 177 1HB LYS+ 134 8.813-2.196-2.274 1.00 0.00 ATOM 178 2HB LYS+ 134 10.523-2.584-2.413 1.00 0.00 ATOM 179 QB LYS+ 134 9.668-2.390-2.344 1.00 0.00 ATOM 180 CG LYS+ 134 9.810-1.222-3.877 1.00 0.00 ATOM 181 1HG LYS+ 134 10.670-0.577-3.987 1.00 0.00 ATOM 182 2HG LYS+ 134 8.907-0.652-4.036 1.00 0.00 ATOM 183 QG LYS+ 134 9.788-0.614-4.012 1.00 0.00 ATOM 184 CD LYS+ 134 9.887-2.331-4. 917 1.00 0.00 ATOM 185 1HD LYS+ 134 9.637-3.272-4.446 1.00 0.00 ATOM 186 2HD LYS+ 134 10.895-2.379-5.304 1.00 0.00 ATOM 187 QD LYS+ 134 10.266-2.825-4.875 1.00 0. 00 ATOM 188 CE LYS+ 134 8.928-2.087-6. 075 1.00 0.00 ATOM 189 1HE LYS+ 134 8.618-3.042-6.475 1.00 0.00 ATOM 190 2HE LYS+ 134 9.446-1.529-6.842 1.00 0.00 ATOM 191 QE LYS+ 134 9.032-2.285-6.659 1.00 0.00 ATOM 192 NZ LYS+ 134 7.721-1.322-5.650 1.00 0.00 ATOM 193 1HZ LYS+ 134 7.909-0.301-5.691 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.459-1.575-4.674 1.00 0. 00 ATOM 195 3HZ LYS+ 134 6.918-1.541-6.275 1.00 0.00 ATOM 196 QZ LYS+ 134 7.428-1.139-5. 547 1.00 0.00 ATOM 197 C LYS+ 134 8.839-0.078-0.917 1.00 0.00 ATOM 198 0 LYS+ 134 7.883-0.745-0.542 1.00 0.00 ATOM 199 N PHE 135 8.828 1.243-0.942 1.00 0.00 ATOM 200 H PHE 135 9.623 1.725-1.250 1.00 0.00 ATOM 201 CA PHE 135 7.660 1.999-0.512 1.00 0.00 ATOM 202 HA PHE 135 7.115 1.397 0.201 1.00 0.00 ATOM 203 CB PHE 135 8.102 3.301 0.161 1.00 0.00 ATOM 204 1HB PHE 135 8.535 3.951-0.587 1.00 0.00 ATOM 205 2HB PHE 135 8.851 3.075 0.903 1.00 0.00 ATOM 206 QB PHE 135 8.693 3.513 0.158 1.00 0.00 ATOM 207 QD PHE 135 6.880 4.148 0.924 1.00 0.00 ATOM 208 QE PHE 135 5.101 5.404 2.064 1.00 0.00 ATOM 209 QR PHE 135 5.634 5.028 1.723 1.00 0.00 ATOM 210 CG PHE 135 7.001 4.062 0.847 1.00 0.00 ATOM 211 CD1 PHE 135 5.882 3.412 1.339 1.00 0. 00 ATOM 212 1HD PHE 135 5.794 2.342 1.219 1.00 0.00 ATOM 213 CE1 PHE 135 4.883 4.115 1.980 1.00 0.00 ATOM 214 1HE PHE 135 4.015 3.595 2.360 1.00 0.00 ATOM 215 CZ PHE 135 4.991 5.481 2.135 1.00 0. 00 ATOM 216 HZ PHE 135 4.208 6.032 2.639 1.00 0.00 ATOM 217 CE2 PHE 135 6.100 6.143 1.649 1.00 0.00 ATOM 218 2HE PHE 135 6.187 7.213 1.769 1.00 0.00 ATOM 219 CD2 PHE 135 7.099 5.434 1.011 1.00 0.00 ATOM 220 2HD PHE 135 7.967 5.954 0.630 1.00 0.00 ATOM 221 C PHE 135 6.762 2.299-1.699 1.00 0.00 ATOM 222 O PHE 135 7.138 3.039-2.603 1.00 0.00 ATOM 223 N LEU 136 5.578 1.714-1.692 1.00 0.00 ATOM 224 H LEU 136 5.335 1.128-0.940 1.00 0.00 ATOM 225 CA LEU 136 4.624 1.911-2.764 1.00 0. 00 ATOM 226 HA LEU 136 5.137 2.388-3.585 1.00 0.00

ATOM 227 CB LEU 136 4.051 0.573-3.237 1.00 0.00 ATOM 228 1HB LEU 136 3.223 0.779-3.901 1.00 0.00 ATOM 229 2HB LEU 136 3.669 0.045-2.374 1.00 0.00 ATOM 230 QB LEU 136 3.446 0.412-3.138 1.00 0.00 ATOM 231 CG LEU 136 5. 034-0.343-3.968 1.00 0.00 ATOM 232 HG LEU 136 5.826 0.255-4.392 1.00 0.00 ATOM 233 QD1 LEU 136 5.799-1.571-2.770 1.00 0.00 ATOM 234 QD2 LEU 136 4.163-1.250-5.367 1.00 0.00 ATOM 235 CD1 LEU 136 5.654-1.336-3.000 1.00 0.00 ATOM 236 1HD1 LEU 136 6. 616-0.970-2.673 1.00 0.00 ATOM 237 2HD1 LEU 136 5.777-2.290-3.491 1.00 0.00 ATOM 238 3HD1 LEU 136 5.005-1.454-2.144 1.00 0.00 ATOM 239 CD2 LEU 136 4.332-1.076-5.100 1.00 0.00 ATOM 240 1HD2 LEU 136 4.714-2.084-5.169 1.00 0.00 ATOM 241 2HD2 LEU 136 4.506-0.558-6.031 1.00 0.00 ATOM 242 3HD2 LEU 136 3.270-1.109-4.901 1.00 0.00 ATOM 243 QQD LEU 136 4.981-1.410-4.069 1.00 0.00 ATOM 244 C LEU 136 3.498 2.812-2.295 1.00 0.00 ATOM 245 O LEU 136 2.422 2.340-1.942 1. 00 0.00 ATOM 246 N HIS+ 137 3.755 4.108-2.296 1. 00 0.00 ATOM 247 H HIS+ 137 4.635 4.422-2.590 1.00 0.00 ATOM 248 CA HIS+ 137 2.760 5.081-1.881 1. 00 0.00 ATOM 249 HA HIS+ 137 2.061 4.590-1.212 1.00 0.00 ATOM 250 CB HIS+ 137 3.436 6.255-1.158 1.00 0.00 ATOM 251 1HB HIS+ 137 4.058 6.784-1.863 1.00 0.00 ATOM 252 2HB HIS+ 137 4.056 5.868-0.363 1.00 0.00 ATOM 253 QB HIS+ 137 4.057 6.326-1.113 1.00 0.00 ATOM 254 CG HIS+ 137 2.481 7.244-0.552 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.566 7.972-1.285 1.00 0.00 ATOM 256 CD2 HIS+ 137 2.300 7.613 0.735 1.00 0.00 ATOM 257 1HD HIS+ 137 1.446 7.938-2.264 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.865 8.739-0.470 1.00 0.00 ATOM 259 NE2 HIS+ 137 1.286 8.539 0.767 1.00 0.00 ATOM 260 2HD HIS+ 137 2.847 7.238 1.590 1.00 0.00 ATOM 261 1HE HIS+ 137 0.076 9.417-0.768 1.00 0.00 ATOM 262 2HE HIS+ 137 0.760 8.752 1.571 1.00 0.00 ATOM 263 C HIS+ 137 2.027 5.587-3.111 1.00 0.00 ATOM 264 O HIS+ 137 2.545 6.437-3.838 1.00 0.00 ATOM 265 N GLN 138 0.839 5.063-3.360 1.00 0.00 ATOM 266 H GLN 138 0.470 4.378-2.754 1.00 0.00 ATOM 267 CA GLN 138 0.076 5.480-4.525 1.00 0.00 ATOM 268 HA GLN 138 0.469 6.435-4.842 1.00 0.00 ATOM 269 CB GLN 138 0.249 4.475-5.666 1.00 0.00 ATOM 270 1HB GLN 138-0.618 4.525-6.308 1.00 0.00 ATOM 271 2HB GLN 138 0.319 3.485-5.248 1.00 0.00 ATOM 272 QB GLN 138-0.150 4.005-5.778 1.00 0.00 ATOM 273 CG GLN 138 1.489 4.727-6.517 1.00 0.00 ATOM 274 1HG GLN 138 1.812 5.747-6.362 1.00 0. 00 ATOM 275 2HG GLN 138 1.231 4.587-7.555 1.00 0.00 ATOM 276 QG GLN 138 1.521 5.167-6.959 1.00 0.00 ATOM 277 CD GLN 138 2.639 3.796-6.176 1.00 0.00 ATOM 278 OE1 GLN 138 2.494 2.576-6.206 1.00 0.00 ATOM 279 NE2 GLN 138 3.796 4.365-5.850 1.00 0.00 ATOM 280 1HE2 GLN 138 3.850 5.346-5.845 1.00 0.00 ATOM 281 2HE2 GLN 138 4.548 3.782-5.626 1.00 0.00 ATOM 282 QE2 GLN 138 4.199 4.564-5.736 1. 00 0.00 ATOM 283 C GLN 138-1.396 5.655-4.189 1.00 0.00 ATOM 284 O GLN 138-1.998 4.833-3.492 1.00 0.00 ATOM 285 N GLU 139-1.958 6. 741-4.685 1. 00 0.00 ATOM 286 H GLU 139-1.411 7.353-5.219 1.00 0.00 ATOM 287 CA GLU 139-3.352 7.071-4.450 1.00 0.00 ATOM 288 HA GLU 139-3.666 6.556-3.554 1.00 0.00 ATOM 289 CB GLU 139-3.500 8.584-4.233 1.00 0.00 ATOM 290 1HB GLU 139-3.638 8.772-3.178 1.00 0.00 ATOM 291 2HB GLU 139-4.374 8.927-4.766 1.00 0.00 ATOM 292 QB GLU 139-4.006 8.850-3.972 1.00 0.00 ATOM 293 CG GLU 139-2.302 9.403-4.708 1.00 0.00 ATOM 294 1HG GLU 139-2.649 10.378-5.016 1.00 0.00 ATOM 295 2HG GLU 139-1.851 8.903-5.552 1.00 0.00 ATOM 296 QG GLU 139-2.250 9.641-5.284 1.00 0.00 ATOM 297 CD GLU 139-1.245 9.584-3.636 1.00 0.00 ATOM 298 OE1 GLU 139-1.400 10.493-2.798 1.00 0.00

ATOM 299 OE2 GLU 139-0.263 8.811-3.635 1.00 0.00 ATOM 300 C GLU 139-4.226 6.613-5.618 1.00 0.00 ATOM 301 O GLU 139-4.270 7.254-6.668 1.00 0.00 ATOM 302 N ARG+ 140-4.925 5.503-5.426 1.00 0.00 ATOM 303 H ARG+ 140-4.857 5.038-4.566 1.00 0.00 ATOM 304 CA ARG+ 140-5.804 4.960-6.455 1.00 0.00 ATOM 305 HA ARG+ 140-5.456 5.313-7.414 1.00 0.00 ATOM 306 CB ARG+ 140-5.760 3.425-6.430 1.00 0.00 ATOM 307 1HB ARG+ 140-6.253 3.082-5.529 1.00 0.00 ATOM 308 2HB ARG+ 140-4.728 3.108-6.405 1.00 0.00 ATOM 309 QB ARG+ 140-5.491 3.095-5.967 1.00 0.00 ATOM 310 CG ARG+ 140-6. 434 2.759-7.621 1.00 0. 00 ATOM 311 1HG ARG+ 140-7.451 3.121-7.691 1.00 0.00 ATOM 312 2HG ARG+ 140-6.441 1.691-7.466 1.00 0.00 ATOM 313 QG ARG+ 140-6.946 2.406-7.579 1.00 0.00 ATOM 314 CD ARG+ 140-5.710 3.066-8.922 1.00 0.00 ATOM 315 1HD ARG+ 140-4. 684 3.320-8.699 1.00 0.00 ATOM 316 2HD ARG+ 140-6.195 3.912-9.393 1.00 0.00 ATOM 317 QD ARG+ 140-5.440 3.616-9.046 1.00 0.00 ATOM 318 NE ARG+ 140-5.732 1.932-9.847 1.00 0.00 ATOM 319 HE ARG+ 140-5.365 1.081-9.525 1.00 0.00 ATOM 320 CZ ARG+ 140-6. 202 2.005-11.095 1.00 0.00 ATOM 321 NH1 ARG+ 140-6.760 3.127-11.529 1.00 0. 00 ATOM 322 1HH1 ARG+ 140-6.835 3.926-10.916 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.121 3.189-12.459 1.00 0.00 ATOM 324 QH1 ARG+ 140-6.978 3.558-11.688 1.00 0.00 ATOM 325 NH2 ARG+ 140-6.142 0.945-11.893 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.743 0.089-11.563 1.00 0.00 ATOM 327 2HH2 ARG+ 140-6.497 0.999-12.828 1.00 0.00 ATOM 328 QH2 ARG+ 140-6.120 0.544-12.196 1.00 0.00 ATOM 329 C ARG+ 140-7.229 5.454-6.230 1.00 0. 00 ATOM 330 O ARG+ 140-8.042 4.768-5.614 1.00 0.00 ATOM 331 N MET 141-7.523 6.654-6.724 1.00 0. 00 ATOM 332 H MET 141-6.825 7.152-7.201 1.00 0.00 ATOM 333 CA MET 141-8.848 7.262-6.568 1.00 0.00 ATOM 334 HA MET 141-9.142 7.147-5.537 1.00 0.00 ATOM 335 CB MET 141-8.770 8.756-6.898 1.00 0.00 ATOM 336 1HB MET 141-8.963 8.886-7.954 1.00 0.00 ATOM 337 2HB MET 141-7.774 9.112-6.678 1.00 0.00 ATOM 338 QB MET 141-8.369 8.999-7.316 1.00 0.00 ATOM 339 CG MET 141-9.764 9.606-6.126 1.00 0.00 ATOM 340 1HG MET 141-9. 362 9.799-5.142 1.00 0.00 ATOM 341 2HG MET 141-10.689 9.057-6.036 1.00 0.00 ATOM 342 QG MET 141-10.026 9.428-5.589 1.00 0.00 ATOM 343 SD MET 141-10. 107 11.184-6.928 1.00 0.00 ATOM 344 QE MET 141-10.914 10.520-8.810 1.00 0.00 ATOM 345 CE MET 141-10.779 10.631-8.495 1.00 0.00 ATOM 346 1HE MET 141-10.856 9.553-8.494 1.00 0. 00 ATOM 347 2HE MET 141-10. 127 10.944-9.297 1.00 0.00 ATOM 348 3HE MET 141-11.758 11.062-8.639 1.00 0.00 ATOM 349 C MET 141-9. 900 6.590-7.457 1.00 0. 00 ATOM 350 O MET 141-10.830 7.243-7.934 1.00 0.00 ATOM 351 N ASP 142-9.747 5.293-7.670 1.00 0.00 ATOM 352 H ASP 142-8.990 4.832-7.260 1.00 0.00 ATOM 353 CA ASP 142-10.663 4.532-8.493 1.00 0.00 ATOM 354 HA ASP 142-11.368 5.217-8.938 1.00 0.00 ATOM 355 CB ASP 142-9.896 3.810-9.601 1.00 0.00 ATOM 356 1HB ASP 142-10.603 3.417-10.305 1.00 0.00 ATOM 357 2HB ASP 142-9.341 2.993-9.169 1.00 0.00 ATOM 358 QB ASP 142-9.972 3.205-9.737 1.00 0.00 ATOM 359 CG ASP 142-8.925 4.703-10.345 1.00 0.00 ATOM 360 OD1 ASP 142-9.212 5.055-11.503 1.00 0.00 ATOM 361 OD2 ASP 142-7.850 5.013-9.788 1.00 0.00 ATOM 362 C ASP 142-11.414 3.501-7.663 1.00 0.00 ATOM 363 O ASP 142-12.630 3.350-7.785 1.00 0.00 ATOM 364 N VAL 143-10.677 2.773-6.833 1.00 0.00 ATOM 365 H VAL 143-9.712 2.927-6.789 1.00 0.00 ATOM 366 CA VAL 143-11.272 1.734-6.005 1.00 0.00 ATOM 367 HA VAL 143-12.207 1.448-6.463 1.00 0.00 ATOM 368 CB VAL 143-10.366 0. 485-5.939 1.00 0.00 ATOM 369 HB VAL 143-9.749 0. 559-5. 053 1.00 0.00 ATOM 370 QG1 VAL 143-11.400-1. 079-5.799 1.00 0.00

ATOM 371 QG2 VAL 143-9.235 0.387-7.440 1.00 0.00 ATOM 372 CG1 VAL 143-11.203-0.779-5.825 1.00 0.00 ATOM 373 1HG1 VAL 143-11.082-1.206-4.839 1.00 0.00 ATOM 374 2HG1 VAL 143-10.875-1.492-6.567 1.00 0.00 ATOM 375 3HG1 VAL 143-12.242-0.540-5.990 1.00 0.00 ATOM 376 CG2 VAL 143-9.451 0.406-7.153 1.00 0.00 ATOM 377 1HG2 VAL 143-9.818 1.067-7.924 1.00 0.00 ATOM 378 2HG2 VAL 143-9.435-0.608-7.525 1.00 0.00 ATOM 379 3HG2 VAL 143-8.452 0.702-6.869 1.00 0.00 ATOM 380 QQG VAL 143-10.318-0.346-6.619 1.00 0.00 ATOM 381 C VAL 143-11.560 2.251-4.595 1.00 0.00 ATOM 382 O VAL 143-10.971 3.234-4.155 1.00 0.00 ATOM 383 N CYS 144-12.484 1. 593-3. 896 1.00 0.00 ATOM 384 H CYS 144-12.926 0.820-4.303 1.00 0.00 ATOM 385 CA CYS 144-12.864 2.001-2.543 1.00 0.00 ATOM 386 HA CYS 144-12.030 2.532-2.099 1.00 0.00 ATOM 387 CB CYS 144-14.074 2.930-2.605 1.00 0.00 ATOM 388 1HB CYS 144-14.644 2.823-1.695 1.00 0.00 ATOM 389 2HB CYS 144-14.691 2.647-3.444 1.00 0.00 ATOM 390 QB CYS 144-14.668 2.735-2.570 1.00 0.00 ATOM 391 SG CYS 144-13.659 4.690-2.797 1.00 0.00 ATOM 392 C CYS 144-13.200 0.795-1.676 1.00 0.00 ATOM 393 O CYS 144-14.374 0.440-1.516 1.00 0.00 ATOM 394 N GLU 145-12.174 0.173-1.120 1.00 0.00 ATOM 395 H GLU 145-11.265 0.507-1.286 1.00 0.00 ATOM 396 CA GLU 145-12.351-0.996-0.275 1.00 0.00 ATOM 397 HA GLU 145-13.385-1.296-0.345 1.00 0.00 ATOM 398 CB GLU 145-11.473-2.129-0.804 1.00 0.00 ATOM 399 1HB GLU 145-11.269-2.824-0.007 1.00 0.00 ATOM 400 2HB GLU 145-10.536-1.710-1.152 1.00 0.00 ATOM 401 QB GLU 145-10.903-2.267-0.580 1.00 0.00 ATOM 402 CG GLU 145-12.116-2.892-1.955 1.00 0.00 ATOM 403 1HG GLU 145-12.628-2.188-2.594 1.00 0.00 ATOM 404 2HG GLU 145-12.831-3.591-1.550 1.00 0.00 ATOM 405 QG GLU 145-12.730-2.889-2.072 1.00 0.00 ATOM 406 CD GLU 145-11.115-3.661-2.790 1.00 0.00 ATOM 407 OE1 GLU 145-10.460-4.570-2.243 1.00 0.00 ATOM 408 OE2 GLU 145-10.994-3.360-3.992 1.00 0.00 ATOM 409 C GLU 145-12.029-0.678 1.186 1.00 0.00 ATOM 410 O GLU 145-11.763 0.475 1.532 1.00 0.00 ATOM 411 N THR 146-12.084-1.698 2.038 1.00 0.00 ATOM 412 H THR 146-12.320-2.587 1.704 1.00 0.00 ATOM 413 CA THR 146-11.829-1.532 3.465 1.00 0.00 ATOM 414 HA THR 146-12.225-0.573 3.766 1.00 0.00 ATOM 415 CB THR 146-12.555-2.638 4.236 1.00 0.00 ATOM 416 HB THR 146-11.885-3.479 4.348 1.00 0.00 ATOM 417 QG2 THR 146-13. 115-2.121 5.950 1.00 0.00 ATOM 418 OG1 THR 146-13.700-3.076 3.522 1.00 0.00 ATOM 419 1HG THR 146-14. 488-2.903 4.045 1.00 0.00 ATOM 420 CG2 THR 146-13. 007-2.222 5.619 1.00 0.00 ATOM 421 1HG2 THR 146-13. 884-2.786 5.899 1.00 0.00 ATOM 422 2HG2 THR 146-13.243-1.166 5.621 1.00 0.00 ATOM 423 3HG2 THR 146-12.217-2.412 6.331 1.00 0.00 ATOM 424 C THR 146-10.330-1.569 3.769 1.00 0.00 ATOM 425 O THR 146-9.519-1.910 2.907 1.00 0.00 ATOM 426 N HIS+ 147-9.977-1.225 5.007 1.00 0.00 ATOM 427 H HIS+ 147-10.680-0.968 5.645 1.00 0.00 ATOM 428 CA HIS+ 147-8.584-1.219 5.452 1.00 0.00 ATOM 429 HA HIS+ 147-8.045-0.501 4.852 1.00 0.00 ATOM 430 CB HIS+ 147-8. 511-0. 795 6.922 1.00 0.00 ATOM 431 1HB HIS+ 147-8. 556-1. 677 7.545 1.00 0.00 ATOM 432 2HB HIS+ 147-9.355-0.159 7.149 1.00 0.00 ATOM 433 QB HIS+ 147-8. 956-0.918 7.347 1.00 0.00 ATOM 434 CG HIS+ 147-7.264-0.045 7.275 1.00 0.00 ATOM 435 ND1 HIS+ 147-7.246 1.312 7.511 1.00 0.00 ATOM 436 CD2 HIS+ 147-5. 989-0.472 7.438 1.00 0.00 ATOM 437 1HD HIS+ 147-8.024 1.914 7.466 1.00 0.00 ATOM 438 CE1 HIS+ 147-6.013 1.689 7.804 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.231 0.626 7.769 1.00 0.00 ATOM 440 2HD HIS+ 147-5.629-1.486 7.311 1.00 0.00 ATOM 441 1HE HIS+ 147-5.699 2.698 8.029 1.00 0.00 ATOM 442 2HE HIS+ 147-4.250 0.649 7.795 1.00 0.00

ATOM 443 C HIS+ 147-7.939-2.593 5.283 1.00 0.00 ATOM 444 O HIS+ 147-6. 761-2.700 4.939 1.00 0.00 ATOM 445 N LEU 148-8.720-3.640 5.525 1.00 0.00 ATOM 446 H LEU 148-9.651-3.489 5.790 1.00 0.00 ATOM 447 CA LEU 148-8.229-5.007 5.401 1.00 0.00 ATOM 448 HA LEU 148-7. 274-5.065 5.902 1.00 0.00 ATOM 449 CB LEU 148-9.206-5.980 6.068 1.00 0.00 ATOM 450 1HB LEU 148-10.203-5.749 5.725 1.00 0.00 ATOM 451 2HB LEU 148-9.165-5.822 7.136 1.00 0.00 ATOM 452 QB LEU 148-9.684-5.785 6.430 1.00 0.00 ATOM 453 CG LEU 148-8.939-7.460 5.792 1.00 0.00 ATOM 454 HG LEU 148-8.592-7.571 4.775 1.00 0. 00 ATOM 455 QD1 LEU 148-7.601-8.118 6.935 1.00 0.00 ATOM 456 QD2 LEU 148-10.517-8.463 5.983 1.00 0.00 ATOM 457 CD1 LEU 148-7.857-7.992 6.717 1.00 0.00 ATOM 458 1HD1 LEU 148-7.837-7.406 7.623 1.00 0.00 ATOM 459 2HD1 LEU 148-6.898-7.926 6.224 1.00 0.00 ATOM 460 3HD1 LEU 148-8.067-9.023 6.960 1.00 0.00 ATOM 461 CD2 LEU 148-10.215-8.271 5.946 1.00 0.00 ATOM 462 1HD2 LEU 148-10.622-8.491 4.971 1.00 0.00 ATOM 463 2HD2 LEU 148-10.935-7.705 6.518 1.00 0.00 ATOM 464 3HD2 LEU 148-9.993-9.195 6.460 1.00 0.00 ATOM 465 QQD LEU 148-9.059-8.291 6.459 1.00 0.00 ATOM 466 C LEU 148-8.039-5.373 3.936 1.00 0.00 ATOM 467 O LEU 148-7.103-6.087 3.579 1.00 0.00 ATOM 468 N HIS+ 149-8.931-4.871 3.094 1.00 0.00 ATOM 469 H HIS+ 149-9. 646-4.303 3.442 1.00 0. 00 ATOM 470 CA HIS+ 149-8.868-5.134 1.664 1.00 0.00 ATOM 471 HA HIS+ 149-8.879-6.205 1.524 1.00 0.00 ATOM 472 CB HIS+ 149-10.080-4.533 0.966 1.00 0.00 ATOM 473 1HB HIS+ 149-9.806-4.265-0.046 1.00 0.00 ATOM 474 2HB HIS+ 149-10.389-3.644 1.495 1.00 0.00 ATOM 475 QB HIS+ 149-10.098-3.954 0.724 1.00 0.00 ATOM 476 CG HIS+ 149-11.252-5.461 0.895 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.824-5.846-0.295 1.00 0.00 ATOM 478 CD2 HIS+ 149-11.960-6.083 1.870 1.00 0.00 ATOM 479 1HD HIS+ 149-11.527-5.551-1.198 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.834-6.663-0.056 1.00 0.00 ATOM 481 NE2 HIS+ 149-12.937-6.824 1.250 1.00 0.00 ATOM 482 2HD HIS+ 149-11.787-6.011 2.934 1.00 0.00 ATOM 483 1HE HIS+ 149-13.467-7.121-0.803 1.00 0.00 ATOM 484 2HE HIS+ 149-13.557-7.439 1.697 1.00 0.00 ATOM 485 C HIS+ 149-7.583-4.579 1.071 1.00 0.00 ATOM 486 O HIS+ 149-6.817-5.313 0.452 1.00 0.00 ATOM 487 N TRP 150-7.338-3.286 1.285 1.00 0.00 ATOM 488 H TRP 150-7.983-2.755 1.801 1.00 0.00 ATOM 489 CA TRP 150-6. 121-2.644 0.786 1.00 0. 00 ATOM 490 HA TRP 150-6.102-2.746-0.290 1.'00 0.00 ATOM 491 CB TRP 150-6. 086-1.164 1.163 1.00 0. 00 ATOM 492 1HB TRP 150-5. 104-0.771 0.940 1.00 0.00 ATOM 493 2HB TRP 150-6. 270-1.068 2.221 1.00 0.00 ATOM 494 QB TRP 150-5.687-0.919 1.580 1.00 0.00 ATOM 495 CG TRP 150-7. 092-0.317 0.448 1.00 0.00 ATOM 496 CD1 TRP 150-7. 604 0.870 0.881 1.00 0.00 ATOM 497 CD2 TRP 150-7. 706-0.577-0.820 1.00 0.00 ATOM 498 CE3 TRP 150-7. 607-1.609-1.755 1.00 0.00 ATOM 499 CE2 TRP 150-8. 575 0.495-1.088 1.00 0.00 ATOM 500 NE1 TRP 150-8. 496 1.360-0.037 1.00 0.00 ATOM 501 HD TRP 150-7. 337 1.342 1.815 1.00 0.00 ATOM 502 3HE TRP 150-6.955-2.451-1.592 1.00 0.00 ATOM 503 CZ3 TRP 150-8. 364-1. 539-2. 902 1.00 0.00 ATOM 504 CZ2 TRP 150-9. 336 0.564-2.247 1.00 0.00 ATOM 505 1HE TRP 150-8. 997 2.198 0.046 1.00 0.00 ATOM 506 3HZ TRP 150-8. 309-2.333-3.631 1.00 0.00 ATOM 507 CH2 TRP 150-9.218-0.460-3.138 1.00 0.00 ATOM 508 2HZ TRP 150-10. 004 1.393-2.448 1.00 0.00 ATOM 509 HH TRP 150-9. 793-0.452-4.052 1.00 0.00 ATOM 510 C TRP 150-4. 895-3.329 1.345 1.00 0.00 ATOM 511 O TRP 150-3. 885-3.436 0.665 1.00 0.00 ATOM 512 N HIS+ 151-4.996-3. 808 2.578 1.00 0.00 ATOM 513 H HIS+ 151-5.840-3.703 3.067 1.00 0.00 ATOM 514 CA HIS+ 151-3.891-4.511 3.204 1.00 0.00

ATOM 515 HA HIS+ 151-3.036-3.852 3.214 1.00 0.00 ATOM 516 CB HIS+ 151-4. 256-4.904 4.646 1.00 0.00 ATOM 517 1HB HIS+ 151-5. 108-5.569 4.619 1.00 0.00 ATOM 518 2HB HIS+ 151-4.522-4.014 5.194 1.00 0.00 ATOM 519 QB HIS+ 151-4.815-4.791 4.906 1.00 0.00 ATOM 520 CG HIS+ 151-3. 157-5.595 5.403 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.756-5.214 6.665 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.387-6.662 5.076 1.00 0.00 ATOM 523 1HD HIS+ 151-3.124-4.466 7.184 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.789-6.015 7.077 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.548-6.902 6.133 1.00 0.00 ATOM 526 2HD HIS+ 151-2.420-7.212 4.142 1.00 0.00 ATOM 527 1HE HIS+ 151-1.271-5.946 8.024 1.00 0. 00 ATOM 528 2HE HIS+ 151-0.975-7.692 6.236 1.00 0.00 ATOM 529 C HIS+ 151-3.561-5. 749 2.382 1.00 0.00 ATOM 530 O HIS+ 151-2.400-6.009 2.077 1.00 0.00 ATOM 531 N THR 152-4.595-6.496 2.021 1.00 0.00 ATOM 532 H THR 152-5.497-6.225 2.294 1.00 0.00 ATOM 533 CA THR 152-4.430-7.701 1.227 1.00 0.00 ATOM 534 HA THR 152-3.687-8.316 1.714 1.00 0.00 ATOM 535 CB THR 152-5.747-8.478 1.157 1.00 0.00 ATOM 536 HB THR 152-6.385-8.020 0.414 1.00 0.00 ATOM 537 QG2 THR 152-5.522-10.279 0.688 1.00 0.00 ATOM 538 OG1 THR 152-6.419-8.447 2.406 1.00 0.00 ATOM 539 1HG THR 152-6.656-7. 539 2.628 1.00 0.00 ATOM 540 CG2 THR 152-5.566-9. 933 0.778 1.00 0.00 ATOM 541 1HG2 THR 152-6.234-10.180-0.033 1.00 0.00 ATOM 542 2HG2 THR 152-5.788-10. 557 1.631 1.00 0.00 ATOM 543 3HG2 THR 152-4.544-10.100 0.466 1.00 0.00 ATOM 544 C THR 152-3.930-7.368-0.175 1.00 0.00 ATOM 545 O THR 152-2.989-7. 984-0.650 1.00 0.00 ATOM 546 N VAL 153-4.545-6.384-0.830 1.00 0.00 ATOM 547 H VAL 153-5.290-5.903-0.400 1.00 0.00 ATOM 548 CA VAL 153-4.119-5. 996-2.172 1.00 0.00 ATOM 549 HA VAL 153-4.192-6. 863-2.805 1.00 0.00 ATOM 550 CB VAL 153-5. 010-4.875-2.758 1.00 0.00 ATOM 551 HB VAL 153-4.868-3.983-2.166 1.00 0.00 ATOM 552 QG1 VAL 153-4.526-4.485-4.535 1.00 0.00 ATOM 553 QG2 VAL 153-6.828-5. 357-2.671 1.00 0.00 ATOM 554 CG1 VAL 153-4.618-4. 560-4.194 1.00 0.00 ATOM 555 1HG1 VAL 153-3.616-4.919-4.382 1.00 0.00 ATOM 556 2HG1 VAL 153-4.653-3.492-4.351 1.00 0.00 ATOM 557 3HG1 VAL 153-5. 307-5.046-4.870 1.00 0.00 ATOM 558 CG2 VAL 153-6.479-5.265-2.687 1.00 0.00 ATOM 559 1HG2 VAL 153-6.652-5.862-1.804 1.00 0.00 ATOM 560 2HG2 VAL 153-6.742-5.837-3.565 1.00 0.00 ATOM 561 3HG2 VAL 153-7.088-4.374-2.644 1.00 0.00 ATOM 562 QQG VAL 153-5.677-4.921-3.603 1.00 0.00 ATOM 563 C VAL 153-2.668-5.544-2.153 1.00 0.00 ATOM 564 O VAL 153-1. 861-5. 983-2. 968 1.00 0.00 ATOM 565 N ALA 154-2.348-4.683-1.205 1.00 0.00 ATOM 566 H ALA 154-3.048-4.383-0.579 1.00 0.00 ATOM 567 CA ALA 154-0.994-4. 176-1.050 1.00 0.00 ATOM 568 HA ALA 154-0.714-3.666-1.960 1.00 0.00 ATOM 569 QB ALA 154-0.942-2. 939 0.362 1.00 0.00 ATOM 570 CB ALA 154-0.952-3.177 0.091 1.00 0.00 ATOM 571 1HB ALA 154-1.959-2. 883 0.352 1.00 0.00 ATOM 572 2HB ALA 154-0.390-2. 306-0.214 1.00 0.00 ATOM 573 3HB ALA 154-0.476-3.630 0.949 1. 00 0.00 ATOM 574 C ALA 154-0.002-5.302-0.783 1.00 0.00 ATOM 575 O ALA 154 1.022-5.418-1.459 1.00 0.00 ATOM 576 N LYS+ 155-0.309-6.119 0.218 1.00 0.00 ATOM 577 H LYS+ 155-1.138-5. 962 0.723 1.00 0.00 ATOM 578 CA LYS+ 155 0.552-7.231 0.603 1.00 0.00 ATOM 579 HA LYS+ 155 1.528-6. 829 0.855 1.00 0.00 ATOM 580 CB LYS+ 155-0.033-7.950 1.826 1.00 0.00 ATOM 581 1HB LYS+ 155-0.676-8. 748 1.480 1.00 0.00 ATOM 582 2HB LYS+ 155-0.628-7.244 2.387 1.00 0.00 ATOM 583 QB LYS+ 155-0. 652-7. 996 1.933 1.00 0.00 ATOM 584 CG LYS+ 155 1.007-8. 549 2.769 1.00 0.00 ATOM 585 1HG LYS+ 155 0.538-8. 743 3.723 1.00 0.00 ATOM 586 2HG LYS+ 155 1.807-7. 838 2.902 1.00 0.00

ATOM 587 QG LYS+ 155 1.172-8.290 3.312 1.00 0.00 ATOM 588 CD LYS+ 155 1.590-9.848 2.234 1.00 0.00 ATOM 589 1HD LYS+ 155 2.444-10.122 2.838 1.00 0.00 ATOM 590 2HD LYS+ 155 1.906-9.695 1.212 1.00 0.00 ATOM 591 QD LYS+ 155 2.175-9.908 2.025 1.00 0.00 ATOM 592 CE LYS+ 155 0.576-10.983 2.269 1.00 0.00 ATOM 593 1HE LYS+ 155-0.416-10.568 2.143 1.00 0.00 ATOM 594 2HE LYS+ 155 0.639-11.480 3.226 1.00 0.00 ATOM 595 QE LYS+ 155 0.111-11.024 2.684 1.00 0.00 ATOM 596 NZ LYS+ 155 0.822-11.975 1.190 1.00 0.00 ATOM 597 1HZ LYS+ 155 0.808-12.938 1.573 1.00 0.00 ATOM 598 2HZ LYS+ 155 1.748-11.802 0.742 1.00 0.00 ATOM 599 3HZ LYS+ 155 0.071-11.897 0.453 1.00 0. 00 ATOM 600 QZ LYS+ 155 0.875-12.212 0.922 1.00 0.00 ATOM 601 C LYS+ 155 0.718-8.206-0.548 1.00 0.00 ATOM 602 O LYS+ 155 1.840-8.593-0.861 1.00 0.00 ATOM 603 N GLU 156-0.390-8.606-1.167 1.00 0.00 ATOM 604 H GLU 156-1.268-8.273.-0.865 1.00 0.00 ATOM 605 CA GLU 156-0.343-9.544-2.276 1.00 0.00 ATOM 606 HA GLU 156 0.131-10.446-1.915 1.00 0.00 ATOM 607 CB GLU 156-1.752-9.894-2.746 1.00 0.00 ATOM 608 1HB GLU 156-1.690-10.360-3.718 1.00 0.00 ATOM 609 2HB GLU 156-2.328-8.984-2.827 1.00 0.00 ATOM 610 QB GLU 156-2.009-9.672-3.273 1.00 0.00 ATOM 611 CG GLU 156-2.488-10.845-1.806 1.00 0.00 ATOM 612 1HG GLU 156-2.863-11.670-2.382 1.00 0.00 ATOM 613 2HG GLU 156-3.316-10.316-1.358 1.00 0.00 ATOM 614 QG GLU 156-3. 090-10.993-1.870 1.00 0.00 ATOM 615 CD GLU 156-1.610-11.388-0.696 1.00 0.00 ATOM 616 OE1 GLU 156-1.812-10.994 0.469 1.00 0.00 ATOM 617 OE2 GLU 156-0.703-12.195-0.986 1.00 0.00 ATOM 618 C GLU 156 0.490-8.998-3.425 1.00 0.00 ATOM 619 O GLU 156 1.268-9.730-4.014 1.00 0.00 ATOM 620 N THR 157 0.348-7.710-3.727 1.00 0.00 ATOM 621 H THR 157-0.285-7.161-3.211 1.00 0.00 ATOM 622 CA THR 157 1.130-7.093-4.800 1.00 0.00 ATOM 623 HA THR 157 0.880-7.597-5.723 1.00 0.00 ATOM 624 CB THR 157 0.780-5.605-4.931 1.00 0.00 ATOM 625 HB THR 157 1.011-5.110-3.998 1.00 0.00 ATOM 626 QG2 THR 157 1.722-4.729-6.295 1.00 0.00 ATOM 627 OG1 THR 157-0.600-5.435-5. 197 1.00 0.00 ATOM 628 1HG THR 157-1.112-5.681-4.415 1.00 0.00 ATOM 629 CG2 THR 157 1.541-4.898-6.032 1.00 0.00 ATOM 630 1HG2 THR 157 0.887-4.197-6.529 1.00 0.00 ATOM 631 2HG2 THR 157 1.899-5.625-6.747 1.00 0.00 ATOM 632 3HG2 THR 157 2.381-4.367-5.607 1.00 0.00 ATOM 633 C THR 157 2.630-7.266-4.536 1.00 0.00 ATOM 634 O THR 157 3.405-7.576-5.442 1.00 0.00 ATOM 635 N CYS 158 3.031-7.072-3.286 1.00 0.00 ATOM 636 H CYS 158 2.366-6.830-2.602 1.00 0.00 ATOM 637 CA CYS 158 4.430-7.217-2.902 1.00 0.00 ATOM 638 HA CYS 158 5.032-6.761-3.674 1.00 0.00 ATOM 639 CB CYS 158 4.682-6.483-1. 584 1.00 0.00 ATOM 640 1HB CYS 158 5.583-6.856-1.133 1.00 0.00 ATOM 641 2HB CYS 158 3.855-6.672-0.919 1.00 0.00 ATOM 642 QB CYS 158 4.719-6.764-1.026 1.00 0.00 ATOM 643 SG CYS 158 4.844-4.669-1.772 1.00 0.00 ATOM 644 C CYS 158 4.820-8.697-2.795 1.00 0.00 ATOM 645 O CYS 158 5.885-9.096-3.270 1.00 0.00 ATOM 646 N SER 159 3.955-9.501-2. 174 1.00 0.00 ATOM 647 H SER 159 3.126-9. 118-1.814 1.00 0.00 ATOM 648 CA SER 159 4.199-10.937-2.002 1.00 0.00 ATOM 649 HA SER 159 5.167-11. 051-1.538 1.00 0.00 ATOM 650 CB SER 159 3.140-11. 554-1.091 1.00 0.00 ATOM 651 1HB SER 159 3.040-12.605-1.327 1.00 0.00 ATOM 652 2HB SER 159 2.194-11.057-1.256 1.00 0.00 ATOM 653 QB SER 159 2.617-11.831-1.292 1.00 0.00 ATOM 654 OG SER 159 3.498-11.422 0.277 1.00 0.00 ATOM 655 HG SER 159 4.445-11.579 0.373 1.00 0.00 ATOM 656 C SER 159 4.210-11.683-3.336 1.00 0.00 ATOM 657 O SER 159 4.891-12.695-3.470 1.00 0.00 ATOM 658 N GLU 160 3.456-11.180-4.315 1.00 0.00

ATOM 659 H GLU 160 2.930-10.368-4.144 1.00 0.00 ATOM 660 CA GLU 160 3.392-11.795-5.640 1.00 0.00 ATOM 661 HA GLU 160 3.087-12.825-5.523 1.00 0.00 ATOM 662 CB GLU 160 2.375-11.055-6.520 1.00 0.00 ATOM 663 1HB GLU 160 2.797-10.101-6.807 1.00 0.00 ATOM 664 2HB GLU 160 1.479-10.881-5.944 1.00 0.00 ATOM 665 QB GLU 160 2.138-10.491-6.376 1.00 0.00 ATOM 666 CG GLU 160 1.987-11.797-7.789 1.00 0.00 ATOM 667 1HG GLU 160 0.913-11.763-7.899 1.00 0.00 ATOM 668 2HG GLU 160 2.309-12.824-7.706 1.00 0.00 ATOM 669 QG GLU 160 1.611-12.293-7.803 1.00 0.00 ATOM 670 CD GLU 160 2.620-11.189-9.019 1.00 0.00 ATOM 671 OE1 GLU 160 2.980-9.994-8.973 1.00 0.00 ATOM 672 OE2 GLU 160 2.800-11.909-10.018 1.00 0.00 ATOM 673 C GLU 160 4.770-11.748-6.285 1.00 0.00 ATOM 674 O GLU 160 5.103-12.537-7.172 1.00 0.00 ATOM 675 N LYS+ 161 5.577-10.816-5.813 1.00 0.00 ATOM 676 H LYS+ 161 5.259-10.230-5.097 1.00 0.00 ATOM 677 CA LYS+ 161 6.921-10.657-6.302 1.00 0.00 ATOM 678 HA LYS+ 161 7.020-11.241-7.205 1.00 0.00 ATOM 679 CB LYS+ 161 7.202-9.184-6.611 1.00 0.00 ATOM 680 1HB LYS+ 161 7.647-8.727-5.738 1.00 0.00 ATOM 681 2HB LYS+ 161 6. 268-8.688-6.825 1.00 0.00 ATOM 682 QB LYS+ 161 6.957-8.707-6.282 1.00 0.00 ATOM 683 CG LYS+ 161 8.145-8.977-7.791 1.00 0.00 ATOM 684 1HG LYS+ 161 9.153-9.209-7.476 1.00 0.00 ATOM 685 2HG LYS+ 161 8.093-7.945-8.103 1.00 0.00 ATOM 686 QG LYS+ 161 8.623-8.577-7.790 1.00 0.00 ATOM 687 CD LYS+ 161 7.779-9.872-8.976 1.00 0.00 ATOM 688 1HD LYS+ 161 7.846-10.905-8.666 1.00 0.00 ATOM 689 2HD LYS+ 161 8.481-9.691-9.777 1.00 0.00 ATOM 690 QD LYS+ 161 8.163-10.298-9.222 1.00 0.00 ATOM 691 CE LYS+ 161 6. 367-9.597-9.491 1.00 0.00 ATOM 692 1HE LYS+ 161 6.428-9.289-10.525 1.00 0.00 ATOM 693 2HE LYS+ 161 5.934-8.799-8.906 1.00 0.00 ATOM 694 QE LYS+ 161 6.181-9.044-9.716 1.00 0.00 ATOM 695 NZ LYS+ 161 5.486-10.794-9.394 1.00 0.00 ATOM 696 1HZ LYS+ 161 4.474-10.497-9.389 1.00 0.00 ATOM 697 2HZ LYS+ 161 5.670-11.321-8.514 1. 00 0.00 ATOM 698 3HZ LYS+ 161 5.633-11.428-10.201 1.00 0.00 ATOM 699 QZ LYS+ 161 5.259-11.082-9.368 1.00 0.00 ATOM 700 C LYS+ 161 7.885-11.196-5.255 1.00 0.00 ATOM 701 O LYS+ 161 7.634-12.236-4.654 1.00 0.00 ATOM 702 N SER 162 8.978-10.497-5.034 1.00 0.00 ATOM 703 H SER 162 9.136-9.677-5.536 1.00 0.00 ATOM 704 CA SER 162 9.952-10.932-4.056 1.00 0.00 ATOM 705 HA SER 162 9.641-11.895-3.686 1.00 0.00 ATOM 706 CB SER 162 11.324-11.074-4.714 1.00 0.00 ATOM 707 1HB SER 162 11.742-12.039-4.462 1.00 0.00 ATOM 708 2HB SER 162 11.977-10.294-4.348 1.00 0.00 ATOM 709 QB SER 162 11.859-11.166-4.405 1.00 0.00 ATOM 710 OG SER 162 11.226-10. 968-6.130 1.00 0.00 ATOM 711 HG SER 162 11.688-11.707-6.535 1.00 0.00 ATOM 712 C SER 162 10.035-9.960-2.886 1.00 0.00 ATOM 713 O SER 162 11.125-9.554-2.497 1.00 0.00 ATOM 714 N THR 163 8.892-9.572-2.320 1.00 0.00 ATOM 715 H THR 163 8.035-9.913-2.664 1.00 0.00 ATOM 716 CA THR 163 8.899-8.649-1.189 1.00 0.00 ATOM 717 HA THR 163 9.843-8.775-0.673 1.00 0.00 ATOM 718 CB THR 163 8.788-7.196-1.649 1.00 0.00 ATOM 719 HB THR 163 8.708-6.573-0.764 1.00 0.00 ATOM 720 QG2 THR 163 10.252-6.581-2.648 1.00 0.00 ATOM 721 OG1 THR 163 7.631-7.010-2.440 1.00 0.00 ATOM 722 1HG THR 163 7.408-7.840-2.884 1.00 0.00 ATOM 723 CG2 THR 163 9.971-6.699-2.455 1.00 0.00 ATOM 724 1HG2 THR 163 9.621-6.283-3.389 1.00 0.00 ATOM 725 2HG2 THR 163 10.642-7.523-2.657 1.00 0.00 ATOM 726 3HG2 THR 163 10.495-5.938-1.896 1.00 0.00 ATOM 727 C THR 163 7.771-8.949-0.203 1.00 0.00 ATOM 728 O THR 163 6.795-9.624-0.526 1.00 0.00 ATOM 729 N ASN 164 7.915-8.422 1.003 1.00 0.00 ATOM 730 H ASN 164 8.723-7.891 1.190 1.00 0.00

ATOM 731 CA ASN 164 6.919-8.604 2.064 1.00 0.00 ATOM 732 HA ASN 164 6.041-9.060 1.620 1.00 0.00 ATOM 733 CB ASN 164 7.466-9.521 3.166 1.00 0.00 ATOM 734 1HB ASN 164 7.252-10.547 2.910 1.00 0.00 ATOM 735 2HB ASN 164 6.980-9.280 4.100 1.00 0.00 ATOM 736 QB ASN 164 7.116-9.913 3.505 1.00 0.00 ATOM 737 CG ASN 164 8.968-9.380 3.359 1.00 0.00 ATOM 738 OD1 ASN 164 9.659-10.353 3.629 1.00 0.00 ATOM 739 ND2 ASN 164 9.474-8.159 3.242 1.00 0.00 ATOM 740 1HD2 ASN 164 8.855-7.422 3.059 1.00 0.00 ATOM 741 2HD2 ASN 164 10.442-8.053 3.291 1.00 0.00 ATOM 742 QD2 ASN 164 9.648-7.737 3.175 1.00 0.00 ATOM 743 C ASN 164 6.531-7.259 2.676 1.00 0. 00 ATOM 744 O ASN 164 7.400-6.449 2.996 1.00 0.00 ATOM 745 N LEU 165 5.232-7.021 2.834 1.00 0.00 ATOM 746 H LEU 165 4.588-7.702 2.559 1.00 0.00 ATOM 747 CA LEU 165 4.741-5.764 3.408 1.00 0.00 ATOM 748 HA LEU 165 5.172-4.943 2.851 1.00 0.00 ATOM 749 CB LEU 165 3.219-5.679 3.319 1.00 0.00 ATOM 750 1HB LEU 165 2.827-5.534 4.316 1.00 0.00 ATOM 751 2HB LEU 165 2.844-6.616 2.935 1.00 0.00 ATOM 752 QB LEU 165 2.835-6.075 3.625 1.00 0.00 ATOM 753 CG LEU 165 2.690-4.556 2.446 1.00 0.00 ATOM 754 HG LEU 165 3.190-3.635 2.709 1.00 0.00 ATOM 755 QD1 LEU 165 3.050-4.920 0.646 1.00 0.00 ATOM 756 QD2 LEU 165 0.846-4.325 2.724 1.00 0.00 ATOM 757 CD1 LEU 165 2.982-4.851 0.994 1.00 0.00 ATOM 758 1HD1 LEU 165 3.765-4.194 0.643 1.00 0.00 ATOM 759 2HD1 LEU 165 2.088-4.689 0.407 1.00 0.00 ATOM 760 3HD1 LEU 165 3. 299-5.877 0.890 1.00 0. 00 ATOM 761 CD2 LEU 165 1.200-4.370 2.671 1.00 0.00 ATOM 762 1HD2 LEU 165 0.666-5.216 2.266 1.00 0.00 ATOM 763 2HD2 LEU 165 0.872-3.467 2.177 1.00 0.00 ATOM 764 3HD2 LEU 165 1.002-4.292 3.730 1.00 0.00 ATOM 765 QQD LEU 165 1.948-4.622 1.685 1.00 0.00 ATOM 766 C LEU 165 5.147-5.618 4. 861 1.00 0.00 ATOM 767 O LEU 165 4.845-6.474 5.690 1.00 0.00 ATOM 768 N HIS+ 166 5.811-4.518 5.157 1.00 0.00 ATOM 769 H HIS+ 166 6.006-3.869 4.448 1.00 0.00 ATOM 770 CA HIS+ 166 6.241-4.228 6.508 1.00 0.00 ATOM 771 HA HIS+ 166 6.023-5.090 7.121 1.00 0.00 ATOM 772 CB HIS+ 166 7.749-3.955 6.539 1.00 0.00 ATOM 773 1HB HIS+ 166 7.955-3.060 5.966 1.00 0.00 ATOM 774 2HB HIS+ 166 8.269-4.788 6.092 1.00 0.00 ATOM 775 QB HIS+ 166 8.112-3.924 6.029 1.00 0.00 ATOM 776 CG HIS+ 166 8.301-3.753 7.915 1.00 0.00 ATOM 777 ND1 HIS+ 166 8.452-4.772 8.831 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.728-2.630. 8.530 1.00 0.00 ATOM 779 1HD HIS+ 166 8.225-5.715 8.683 1.00 0.00 ATOM 780 CE1 HIS+ 166 8. 948-4. 278 9.953 1.00 0.00 ATOM 781 NE2 HIS+ 166 9.124-2.977 9.795 1.00 0.00 ATOM 782 2HD HIS+ 166 8.736-1.632 8.105 1.00 0.00 ATOM 783 1HE HIS+ 166 9.170-4.842 10.848 1.00 0.00 ATOM 784 2HE HIS+ 166 9.280-2.340 10.524 1.00 0. 00 ATOM 785 C HIS+ 166 5.464-3.027 7.048 1.00 0.00 ATOM 786 O HIS+ 166 4.881-3.091 8.131 1.00 0.00 ATOM 787 N ASP 167 5.454-1.939 6.279 1.00 0.00 ATOM 788 H ASP 167 5.933-1. 956 5.422 1.00 0.00 ATOM 789 CA ASP 167 4.746-0.721 6.682 1.00 0.00 ATOM 790 HA ASP 167 4.263-0.922 7.627 1.00 0.00 ATOM 791 CB ASP 167 5.718 0.455 6.864 1.00 0.00 ATOM 792 1HB ASP 167 5.313 1.130 7.604 1.00 0.00 ATOM 793 2HB ASP 167 5.814 0.978 5.925 1.00 0.00 ATOM 794 QB ASP 167 5.563 1.054 6.764 1.00 0.00 ATOM 795 CG ASP 167 7.102 0.034 7.313 1.00 0.00 ATOM 796 OD1 ASP 167 7.378 0.104 8.528 1.00 0.00 ATOM 797 OD2 ASP 167 7.913-0.367 6.449 1.00 0.00 ATOM 798 C ASP 167 3.680-0.334 5.659 1.00 0.00 ATOM 799 0 ASP 167 3.958 0.370 4.691 1.00 0.00 ATOM 800 N TYR 168 2.462-0.801 5.877 1.00 0.00 ATOM 801 H TYR 168 2.305-1.358 6.668 1.00 0.00 ATOM 802 CA TYR 168 1.338-0.509 4.984 1.00 0.00

ATOM 803 HA TYR 168 1.731-0.303 3.991 1.00 0.00 ATOM 804 CB TYR 168 0.402-1.719 4.915 1.00 0.00 ATOM 805 1HB TYR 168 0.776-2.415 4.180 1.00 0.00 ATOM 806 2HB TYR 168-0.584-1.387 4.623 1.00 0.00 ATOM 807 QB TYR 168 0.096-1.901 4.401 1.00 0.00 ATOM 808 QD TYR 168 0.264-2.536 6.388 1.00 0.00 ATOM 809 QE TYR 168 0.076-3.706 8.541 1.00 0.00 ATOM 810 QR TYR 168 0.170-3.121 7.464 1.00 0.00 ATOM 811 CG TYR 168 0.277-2.452 6.235 1.00 0.00 ATOM 812 CD1 TYR 168 1.129-3.503 6.554 1.00 0.00 ATOM 813 1HD TYR 168 1.884-3.803 5.842 1.00 0.00 ATOM 814 CE1 TYR 168 1.027-4.162 7.763 1.00 0.00 ATOM 815 1HE TYR 168 1.700-4.976 7.993 1.00 0.00 ATOM 816 CZ TYR 168 0.064-3.776 8.670 1.00 0.00 ATOM 817 CE2 TYR 168-0.794-2.738 8.377 1.00 0.00 ATOM 818 2HE TYR 168-1.548-2.436 9.089 1.00 0.00 ATOM 819 CD2 TYR 168-0. 685-2.083 7.167 1.00 0.00 ATOM 820 2HD TYR 168-1. 355-1.269 6.935 1.00 0.00 ATOM 821 OH TYR 168-0.043-4.431 9.873 1.00 0.00 ATOM 822 HH TYR 168 0.698-4.189 10.436 1.00 0.00 ATOM 823 C TYR 168 0.558 0.714 5.459 1.00 0.00 ATOM 824 O TYR 168 0.495 1.000 6.654 1.00 0.00 ATOM 825 N GLY 169-0.051 1.411 4.517 1.00 0.00 ATOM 826 H GLY 169 0.025 1.124 3.582 1.00 0.00 ATOM 827 CA GLY 169-0.838 2.582 4.835 1.00 0.00 ATOM 828 1HA GLY 169-0.210 3.459 4.773 1.00 0.00 ATOM 829 2HA GLY 169-1.223 2.488 5.840 1.00 0.00 ATOM 830 QA GLY 169-0.717 2.974 5.306 1.00 0.00 ATOM 831 C GLY 169-1.986 2.727 3.868 1.00 0.00 ATOM 832 O GLY 169-1.953 2.147 2.785 1.00 0.00 ATOM 833 N MET 170-3.001 3.481 4.245 1.00 0.00 ATOM 834 H MET 170-2.976 3.918 5.122 1.00 0.00 ATOM 835 CA MET 170-4.159 3.682 3.386 1.00 0.00 ATOM 836 HA MET 170-3.868 3.440 2.365 1.00 0.00 ATOM 837 CB MET 170-5.315 2.774 3.818 1.00 0.00 ATOM 838 1HB MET 170-6.220 3.110 3.331 1.00 0.00 ATOM 839 2HB MET 170-5.442 2.858 4.887 1.00 0.00 ATOM 840 QB MET 170-5.831 2.984 4.109 1.00 0.00 ATOM 841 CG MET 170-5.106 1.308 3.475 1.00 0.00 ATOM 842 1HG MET 170-4.529 1.245 2.563 1.00 0.00 ATOM 843 2HG MET 170-6.070 0.846 3.321 1.00 0.00 ATOM 844 QG MET 170-5.300 1.046 2.942 1.00 0.00 ATOM 845 SD MET 170-4.237 0.407 4.773 1.00 0.00 ATOM 846 QE MET 170-3.236-1.110 3.629 1.00 0.00 ATOM 847 CE MET 170-3.403-0.856 3.821 1. 00 0.00 ATOM 848 1HE MET 170-3.095-0.446 2.870 1.00 0.00 ATOM 849 2HE MET 170-4.077-1.684 3.654 1.00 0.00 ATOM 850 3HE MET 170-2.536-1.201 4.363 1.00 0.00 ATOM 851 C MET 170-4.590 5.138 3.445 1.00 0.00 ATOM 852 O MET 170-4.872 5.667 4.520 1.00 0.00 ATOM 853 N LEU 171-4.618 5.786 2.296 1.00 0.00 ATOM 854 H LEU 171-4.367 5.314 1.473 1.00 0.00 ATOM 855 CA LEU 171-4.987 7.189 2.228 1.00 0.00 ATOM 856 HA LEU 171-5.225 7.513 3.230 1.00 0.00 ATOM 857 CB LEU 171-3.802 8.011 1.712 1.00 0.00 ATOM 858 1HB LEU 171-2.997 7.930 2.429 1.00 0.00 ATOM 859 2HB LEU 171-4.106 9.045 1.655 1.00 0.00 ATOM 860 QB LEU 171-3.552 8.488 2.042 1.00 0.00 ATOM 861 CG LEU 171-3.265 7.591 0.341 1.00 0.00 ATOM 862 HG LEU 171-4.035 7.056-0.194 1.00 0.00 ATOM 863 QD1 LEU 171-2.794 9.096-0.672 1.00 0.00 ATOM 864 QD2 LEU 171-1.780 6.454 0.523 1.00 0.00 ATOM 865 CD1 LEU 171-2.886 8.808-0.477 1.00 0.00 ATOM 866 1HD1 LEU 171-2.523 9.584 0.179 1.00 0.00 ATOM 867 2HD1 LEU 171-3.749 9.165-1.017 1.00 0.00 ATOM 868 3HD1 LEU 171-2.108 8.539-1.178 1.00 0.00 ATOM 869 CD2 LEU 171-2.065 6.671 0.488 1.00 0.00 ATOM 870 1HD2 LEU 171-1.347 6.891-0.288 1.00 0.00 ATOM 871 2HD2 LEU 171-2.385 5.644 0.402 1.00 0.00 ATOM 872 3HD2 LEU 171-1.607 6.826 1.455 1.00 0.00 ATOM 873 QQD LEU 171-2.287 7.775-0.075 1.00 0.00 ATOM 874 C LEU 171-6.206 7.409 1.338 1.00 0.00

ATOM 875 O LEU 171-6.866 6.454 0.925 1.00 0.00 ATOM 876 N LEU 172-6.482 8.684 1.052 1.00 0.00 ATOM 877 H LEU 172-5.898 9.378 1.422 1.00 0.00 ATOM 878 CA LEU 172-7.610 9.098 0.209 1.00 0.00 ATOM 879 HA LEU 172-7.739 10.161 0.342 1.00 0.00 ATOM 880 CB LEU 172-7.304 8.829-1.269 1.00 0.00 ATOM 881 1HB LEU 172-8.133 8.275-1.685 1.00 0.00 ATOM 882 2HB LEU 172-6.419 8.212-1.330 1.00 0.00 ATOM 883 QB LEU 172-7.276 8.244-1.508 1.00 0.00 ATOM 884 CG LEU 172-7.086 10.076-2.130 1.00 0.00 ATOM 885 HG LEU 172-7.922 10.748-2.001 1.00 0.00 ATOM 886 QD1 LEU 172-5.524 10.987-1.611 1.00 0.00 ATOM 887 QD2 LEU 172-6.992 9.607-3.948 1.00 0.00 ATOM 888 CD1 LEU 172-5.824 10.812-1.710 1.00 0.00 ATOM 889 lHDl LEU 172-5.086 10.739-2.496 1.00 0.00 ATOM 890 2HD1 LEU 172-5.431 10.369-0.807 1.00 0.00 ATOM 891 3HD1 LEU 172-6.055 11.851-1.530 1.00 0.00 ATOM 892 CD2 LEU 172-7.011 9.697-3.599 1.00 0.00 ATOM 893 1HD2 LEU 172-5.977 9.686-3.915 1.00 0.00 ATOM 894 2HD2 LEU 172-7.558 10.419-4.187 1.00 0.00 ATOM 895 3HD2 LEU 172-7.440 8.716-3.741 1.00 0.00 ATOM 896 QQD LEU 172-6.258 10.297-2.780 1.00 0.00 ATOM 897 C LEU 172-8.917 8.402 0.592 1.00 0.00 ATOM 898 O LEU 172-9.478 7.657-0.210 1.00 0.00 ATOM 899 N PRO 173-9.438 8.643 1.808 1.00 0.00 ATOM 900 CD PRO 173-8.867 9.534 2.837 1.00 0.00 ATOM 901 CA PRO 173-10.692 8.027 2.247 1.00 0.00 ATOM 902 HA PRO 173-10.623 6.947 2.240 1.00 0.00 ATOM 903 CB PRO 173-10.867 8.524 3.687 1.00 0.00 ATOM 904 1HB PRO 173-10.549 7.755 4.376 1.00 0.00 ATOM 905 2HB PRO 173-11.907 8.760 3.863 1.00 0.00 ATOM 906 QB PRO 173-11.228 8.258 4.119 1.00 0.00 ATOM 907 CG PRO 173-10.008 9.740 3.793 1.00 0.00 ATOM 908 1HG PRO 173-9.638 9.839 4.803 1.00 0.00 ATOM 909 2HG PRO 173-10.577 10.615 3.515 1.00 0.00 ATOM 910 QG PRO 173-10.108 10.227 4.159 1.00 0.00 ATOM 911 1HD PRO 173-8.035 9.059 3.338 1.00 0.00 ATOM 912 2HD PRO 173-8.562 10.476 2.406 1.00 0.00 ATOM 913 QD PRO 173-8.299 9.768 2.872 1.00 0.00 ATOM 914 C PRO 173-11.873 8.462 1.384 1.00 0.00 ATOM 915 O PRO 173-11.946 9.612 0.946 1.00 0.00 ATOM 916 N CYS 174-12.792 7.542 1.135 1.00 0.00 ATOM 917 H CYS 174-12.679 6.639 1.508 1.00 0.00 ATOM 918 CA CYS 174-13.968 7.839 0.325 1.00 0.00 ATOM 919 HA CYS 174-13.983 8.904 0.146 1.00 0.00 ATOM 920 CB CYS 174-13.910 7.111-1.015 1.00 0.00 ATOM 921 1HB CYS 174-13.176 7.590-1.645 1.00 0.00 ATOM 922 2HB CYS 174-14.879 7.173-1.489 1.00 0.00 ATOM 923 QB CYS 174-14.028 7.382-1.567 1.00 0.00 ATOM 924 SG CYS 174-13.470 5.351-0.890 1.00 0.00 ATOM 925 C CYS 174-15.234 7.453 1.071 1.00 0.00 ATOM 926 O CYS 174-16.334 7.861 0.706 1.00 0.00 ATOM 927 N GLY 175-15.064 6.672 2.124 1.00 0.00 ATOM 928 H GLY 175-14.157 6.387 2.370 1.00 0.00 ATOM 929 CA GLY 175-16.185 6.247 2.930 1.00 0.00 ATOM 930 1HA GLY 175-16.494 5.262 2.619 1.00 0.00 ATOM 931 2HA GLY 175-17.004 6.939 2.793 1.00 0.00 ATOM 932 QA GLY 175-16.749 6. 101 2.706 1.00 0.00 ATOM 933 C GLY 175-15.804 6.209 4.387 1.00 0.00 ATOM 934 O GLY 175-14.687 6.588 4.732 1.00 0.00 ATOM 935 N ILE 176-16.714 5.748 5.239 1.00 0.00 ATOM 936 H ILE 176-17.582 5.455 4.899 1.00 0.00 ATOM 937 CA ILE 176-16.439 5.655 6.669 1.00 0.00 ATOM 938 HA ILE 176-16.255 6.652 7.044 1.00 0.00 ATOM 939 CB ILE 176-17.630 5.045 7.441 1.00 0.00 ATOM 940 HB ILE 176-17.493 3.975 7.472 1.00 0.00 ATOM 941 QG2 ILE 176-17.664 5.680 9.212 1.00 0.00 ATOM 942 CG2 ILE 176-17.656 5.558 8.873 1.00 0.00 ATOM 943 1HG2 ILE 176-18.423 5.036 9.427 1.00 0.00 ATOM 944 2HG2 ILE 176-17.871 6.617 8.873 1.00 0.00 ATOM 945 3HG2 ILE 176-16.696 5.385 9.336 1.00 0.00 ATOM 946 CG1 ILE 176-18.954 5.361 6.741 1.00 0.00

ATOM 947 1HG1 ILE 176-18.859 5.150 5.687 1.00 0.00 ATOM 948 2HG1 ILE 176-19.185 6.407 6.876 1.00 0.00 ATOM 949 QG1 ILE 176-19.022 5. 779 6. 281 1.00 0.00 ATOM 950 QD1 ILE 176-20.399 4.367 7.400 1.00 0.00 ATOM 951 CD1 ILE 176-20.121 4.557 7.273 1.00 0.00 ATOM 952 1HD1 ILE 176-20.996 4.748 6.669 1.00 0.00 ATOM 953 2HD1 ILE 176-20.319 4.846 8.295 1.00 0.00 ATOM 954 3HD1 ILE 176-19.880 3.505 7.237 1.00 0.00 ATOM 955 C ILE 176-15. 195 4.797 6.901 1.00 0.00 ATOM 956 O ILE 176-14. 247 5.221 7.558 1.00 0.00 ATOM 957 N ASP 177-15.206 3.603 6.317 1.00 0.00 ATOM 958 H ASP 177-15.984 3.343 5.787 1.00 0.00 ATOM 959 CA ASP 177-14.078 2.683 6.409 1.00 0.00 ATOM 960 HA ASP 177-13. 256 3.209 6. 875 1.00 0.00 ATOM 961 CB ASP 177-14.428 1.451 7.252 1.00 0.00 ATOM 962 1HB ASP 177-15.043 0.785 6.667 1.00 0.00 ATOM 963 2HB ASP 177-14.976 1.765 8.128 1.00 0.00 ATOM 964 QB ASP 177-15.010 1.275 7.397 1.00 0.00 ATOM 965 CG ASP 177-13.195 0.689 7.708 1.00 0.00 ATOM 966 OD1 ASP 177-12.066 1.166 7.456 1.00 0. 00 ATOM 967 OD2 ASP 177-13.357-0.390 8.312 1.00 0.00 ATOM 968 C ASP 177-13.658 2.259 5.003 1.00 0.00 ATOM 969 O ASP 177-13.398 1.085 4.729 1.00 0.00 ATOM 970 N LYS+ 178-13.599 3.232 4.104 1.00 0.00 ATOM 971 H LYS+ 178-13.816 4.148 4.380 1.00 0.00 ATOM 972 CA LYS+ 178-13.206 2.976 2.726 1.00 0.00 ATOM 973 HA LYS+ 178-12.766 1.990 2.684 1.00 0.00 ATOM 974 CB LYS+ 178-14.396 3.041 1.766 1.00 0.00 ATOM 975 1HB LYS+ 178-14.053 2.766 0.778 1.00 0.00 ATOM 976 2HB LYS+ 178-14.755 4.056 1.736 1.00 0.00 ATOM 977 QB LYS+ 178-14.404 3.411 1.257 1.00 0.00 ATOM 978 CG LYS+ 178-15.555 2.127 2.144 1.00 0.00 ATOM 979 1HG LYS+ 178-16.438 2.436 1.607 1.00 0.00 ATOM 980 2HG LYS+ 178-15.730 2.210 3.208 1.00 0.00 ATOM 981 QG LYS+ 178-16.084 2.323 2.407 1.00 0.00 ATOM 982 CD LYS+ 178-15.249 0.673 1.810 1.00 0.00 ATOM 983 1HD LYS+ 178-14.886 0.180 2.704 1.00 0.00 ATOM 984 2HD LYS+ 178-14.483 0.641 1.049 1.00 0.00 ATOM 985 QD LYS+ 178-14.685 0.411 1.876 1.00 0.00 ATOM 986 CE LYS+ 178-16. 479-0.067 1.303 1.00 0.00 ATOM 987 1HE LYS+ 178-17.144-0.246 2.136 1.00 0.00 ATOM 988 2HE LYS+ 178-16.166-1.013 0.885 1.00 0.00 ATOM 989 QE LYS+ 178-16. 655-0.629 1.510 1.00 0.00 ATOM 990 NZ LYS+ 178-17.206 0.708 0.256 1.00 0.00 ATOM 991 1HZ LYS+ 178-17.260 0.155-0.625 1.00 0.00 ATOM 992 2HZ LYS+ 178-16.709 1.598 0. 059 1.00 0. 00 ATOM 993 3HZ LYS+ 178-18.172 0.926 0.575 1.00 0.00 ATOM 994 QZ LYS+ 178-17.381 0.893 0.003 1.00 0.00 ATOM 995 C LYS+ 178-12.160 3.978 2.299 1.00 0.00 ATOM 996 O LYS+ 178-12.270 5. 171 2.585 1.00 0.00 ATOM 997 N PHE 179-11.149 3.488 1.617 1.00 0.00 ATOM 998 H PHE 179-11.127 2.530 1.418 1.00 0.00 ATOM 999 CA PHE 179-10.069 4.331 1.156 1.00 0.00 ATOM 1000 HA PHE 179-10. 342 5.358 1.343 1.00 0.00 ATOM 1001 CB PHE 179-8.780 4.010 1.911 1.00 0.00 ATOM 1002 1HB PHE 179-8.049 4.748 1.659 1.00 0.00 ATOM 1003 2HB PHE 179-8.416 3.045 1.598 1.00 0.00 ATOM 1004 QB PHE 179-8.233 3.897 1.628 1.00 0.00 ATOM 1005 QD PHE 179-8.945 3.993 3.574 1.00 0.00 ATOM 1006 QE PHE 179-9.202 3.984 6.020 1.00 0.00 ATOM 1007 QR PHE 179-9.125 3.987 5.286 1.00 0.00 ATOM 1008 CG PHE 179-8.928 3.995 3.408 1.00 0.00 ATOM 1009 CD1 PHE 179-9.402 2.869 4.065 1.00 0.00 ATOM 1010 1HD PHE 179-9.662 1.991 3.493 1.00 0.00 ATOM 1011 CE1 PHE 179-9.547 2.862 5.438 1.00 0.00 ATOM 1012 1HE PHE 179-9.922 1.979 5.939 1.00 0. 00 ATOM 1013 CZ PHE 179-9.216 3.984 6. 172 1.00 0.00 ATOM 1014 HZ PHE 179-9. 331 3.981 7.246 1.00 0.00 ATOM 1015 CE2 PHE 179-8.740 5.110 5.529 1.00 0. 00 ATOM 1016 2HE PHE 179-8.481 5.989 6.101 1.00 0. 00 ATOM 1017 CD2 PHE 179-8.600 5.113 4.155 1.00 0.00 ATOM 1018 2HD PHE 179-8.227 5.995 3.655 1.00 0.00

ATOM 1019 C PHE 179-9.835 4.140-0.324 1.00 0.00 ATOM 1020 O PHE 179-10.535 3.368-0.977 1.00 0.00 ATOM 1021 N ARG+ 180-8.832 4.831-0.836 1.00 0.00 ATOM 1022 H ARG+ 180-8.309 5.416-0.246 1.00 0.00 ATOM 1023 CA ARG+ 180-8.472 4.738-2.239 1.00 0.00 ATOM 1024 HA ARG+ 180-8.917 3.840-2.642 1.00 0.00 ATOM 1025 CB ARG+ 180-8.999 5.950-3.013 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.642 5.887-4.031 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.609 6.848-2.565 1.00 0.00 ATOM 1028 QB ARG+ 180-8.626 6.368-3.298 1.00 0.00 ATOM 1029 CG ARG+ 180-10.513 6. 047-3.044 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.893 5.897-2.043 1.00 0.00 ATOM 1031 2HG ARG+ 180-10.897 5.271-3.694 1.00 0. 00 ATOM 1032 QG ARG+ 180-10.895 5.584-2.869 1.00 0.00 ATOM 1033 CD ARG+ 180-10.982 7.396-3.559 1.00 0.00 ATOM 1034 1HD ARG+ 180-11.973 7.280-3.973 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.305 7.725-4.334 1.00 0.00 ATOM 1036 QD ARG+ 180-11.139 7.503-4.154 1.00 0.00 ATOM 1037 NE ARG+ 180-11.022 8.405-2.500 1.00 0.00 ATOM 1038 HE ARG+ 180-10.635 8.160-1.624 1.00 0.00 ATOM 1039 CZ ARG+ 180-11.550 9.620-2.657 1.00 0.00 ATOM 1040 NH1 ARG+ 180-12.068 9.970-3.830 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.060 9.322-4.594 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-12.463 10.881-3.957 1.00 0.00 ATOM 1043 QH1 ARG+ 180-12. 262 10.102-4.276 1.00 0.00 ATOM 1044 NH2 ARG+ 180-11.572 10.476-1.642 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-11.195 10.210-0.749 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-11.962 11.390-1.761 1.00 0.00 ATOM 1047 QH2 ARG+ 180-11.579 10.800-1.255 1.00 0.00 ATOM 1048 C ARG+ 180-6.959 4. 658-2.402 1.00 0.00 ATOM 1049 O ARG+ 180-6.456 4. 237-3.434 1.00 0.00 ATOM 1050 N GLY 181-6. 228 5.075-1.383 1.00 0.00 ATOM 1051 H GLY 181-6.668 5.406-0.568 1. 00 0.00 ATOM 1052 CA GLY 181-4.784 5.052-1.473 1.00 0.00 ATOM 1053 1HA GLY 181-4.402 6.024-1.197 1.00 0.00 ATOM 1054 2HA GLY 181-4.506 4. 847-2.496 1.00 0.00 ATOM 1055 QA GLY 181-4.454 5.436-1.847 1.00 0.00 ATOM 1056 C GLY 181-4.151 4.011-0.586 1.00 0.00 ATOM 1057 O GLY 181-4.722 3.620 0.430 1.00 0.00 ATOM 1058 N VAL 182-2.962 3.570-0.973 1.00 0.00 ATOM 1059 H VAL 182-2.567 3.936-1.788 1.00 0.00 ATOM 1060 CA VAL 182-2.217 2.572-0.221 1.00 0.00 ATOM 1061 HA VAL 182-2.551 2.605 0.807 1.00 0.00 ATOM 1062 CB VAL 182-2.432 1.137-0.770 1.00 0.00 ATOM 1063 HB VAL 182-1.635 0.925-1.469 1.00 0.00 ATOM 1064 QG1 VAL 182-2.330-0.121 0.621 1.00 0.00 ATOM 1065 QG2 VAL 182-4.072 0.969-1.683 1.00 0.00 ATOM 1066 CG1 VAL 182-2.349 0.120 0.355 1.00 0.00 ATOM 1067 1HG1 VAL 182-2.266 0.635 1.301 1.00 0.00 ATOM 1068 2HG1 VAL 182-1.483-0.509 0.208 1.00 0.00 ATOM 1069 3HG1 VAL 182-3.240-0.490 0.354 1.00 0.00 ATOM 1070 CG2 VAL 182-3.758 1.000-1.508 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.636 1.328-2.530 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.506 1.610-1.021 1.00 0.00 ATOM 1073 3HG2 VAL 182-4.072-0.033-1.496 1.00 0.00 ATOM 1074 QQG VAL 182-3.201 0.424-0.531 1.00 0.00 ATOM 1075 C VAL 182-0.723 2.895-0.266 1.00 0.00 ATOM 1076 O VAL 182-0.159 3.094-1.340 1.00 0.00 ATOM 1077 N GLU 183-0.096 2.945 0.903 1.00 0.00 ATOM 1078 H GLU 183-0.609 2.779 1.723 1.00 0.00 ATOM 1079 CA GLU 183 1.333 3.237 1.017 1.00 0.00 ATOM 1080 HA GLU 183 1.753 3.292 0.020 1.00 0.00 ATOM 1081 CB GLU 183 1.547 4.572 1.737 1.00 0.00 ATOM 1082 1HB GLU 183 1.801 5.325 1.006 1.00 0.00 ATOM 1083 2HB GLU 183 2.371 4.464 2.428 1.00 0.00 ATOM 1084 QB GLU 183 2.086 4.895 1.717 1.00 0.00 ATOM 1085 CG GLU 183 0.338 5.063 2.523 1.00 0.00 ATOM 1086 1HG GLU 183 0.097 4.333 3.282 1.00 0.00 ATOM 1087 2HG GLU 183-0.497 5.169 1.848 1. 00 0.00 ATOM 1088 QG GLU 183-0.200 4.751 2.565 1. 00 0.00 ATOM 1089 CD GLU 183 0.589 6.396 3.196 1.00 0.00 ATOM 1090 OE1 GLU 183-0.288 7.280 3.109 1.00 0.00

ATOM 1091 OE2 GLU 183 1.670 6.565 3.790 1.00 0.00 ATOM 1092 C GLU 183 2.021 2.121 1.794 1.00 0.00 ATOM 1093 O GLU 183 2.037 2.129 3.018 1.00 0.00 ATOM 1094 N PHE 184 2.553 1.141 1.090 1.00 0.00 ATOM 1095 H PHE 184 2.490 1.162 0.117 1.00 0.00 ATOM 1096 CA PHE 184 3.187 0.004 1.746 1.00 0.00 ATOM 1097 HA PHE 184 3.094 0.159 2.809 1.00 0.00 ATOM 1098 CB PHE 184 2.462-1.296 1.381 1.00 0.00 ATOM 1099 1HB PHE 184 1.603-1.413 2.027 1.00 0.00 ATOM 1100 2HB PHE 184 3.133-2.127 1.546 1.00 0.00 ATOM 1101 QB PHE 184 2.368-1.770 1.786 1.00 0.00 ATOM 1102 QD PHE 184 1.925-1.383-0.215 1.00 0.00 ATOM 1103 QE PHE 184 1.125-1.561-2.531 1.00 0.00 ATOM 1104 QR PHE 184 1.364-1.509-1.836 1.00 0.00 ATOM 1105 CG PHE 184 1.982-1.375-0.051 1.00 0.00 ATOM 1106 CD1 PHE 184 0.933-0.586-0.503 1.00 0.00 ATOM 1107 1HD PHE 184 0.465 0. 113 0.176 1.00 0.00 ATOM 1108 CE1 PHE 184 0.480-0.685-1.804 1.00 0.00 ATOM 1109 1HE PHE 184-0.337-0.064-2.141 1.00 0.00 ATOM 1110 CZ PHE 184 1.075-1.574-2.674 1.00 0.00 ATOM 1111 HZ PHE 184 0.718-1.659-3.689 1.00 0.00 ATOM 1112 CE2 PHE 184 2.121-2.361-2.241 1.00 0.00 ATOM 1113 2HE PHE 184 2.588-3.058-2.921 1.00.0.00 ATOM 1114 CD2 PHE 184 2.567-2.261-0.939 1.00 0.00 ATOM 1115 2HD PHE 184 3.386-2.880-0.605 1.00 0.00 ATOM 1116 C PHE 184 4.663-0.132 1.413 1.00 0.00 ATOM 1117 O PHE 184 5.066-0.034 0.260 1.00 0.00 ATOM 1118 N VAL 185 5.460-0.386 2.439 1.00 0.00 ATOM 1119 H VAL 185 5.069-0.468 3.336 1.00 0.00 ATOM 1120 CA VAL 185 6.891-0.567 2.279 1.00 0.00 ATOM 1121 HA VAL 185 7.168-0.246 1.284 1.00 0.00 ATOM 1122 CB VAL 185 7.685 0.267 3.313 1.00 0.00 ATOM 1123 HB VAL 185 7.893-0.362 4.171 1.00 0.00 ATOM 1124 QG1 VAL 185 9.318 0.841 2.597 1.00 0.00 ATOM 1125 QG2 VAL 185 6.689 1.748 3.908 1.00 0.00 ATOM 1126 CG1 VAL 185 9.006 0.729 2.734 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.206 0.194 1.818 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.795 0.539 3.446 1.00 0.00 ATOM 1129 3HG1 VAL 185 8.955 1.789 2.529 1.00 0.00 ATOM 1130 CG2 VAL 185 6.880 1.464 3.793 1.00 0.00 ATOM 1131 1HG2 VAL 185 5.825 1.234 3.746 1.00 0.00 ATOM 1132 2HG2 VAL 185 7.091 2.317 3.165 1.00 0.00 ATOM 1133 3HG2 VAL 185 7.151 1.693 4.814 1.00 0.00 ATOM 1134 QQG VAL 185 8.004 1.295 3.253 1.00 0.00 ATOM 1135 C VAL 185 7.233-2.048 2.437 1.00 0.00 ATOM 1136 O VAL 185 7.201-2.589 3.540 1.00 0.00 ATOM 1137 N CYS 186 7.536-2.712 1.329 1.00 0.00 ATOM 1138 H CYS 186 7.529-2.238 0.467 1.00 0.00 ATOM 1139 CA CYS 186 7.862-4.133 1.364 1.00 0.00 ATOM 1140 HA CYS 186 7.690-4.480 2.375 1.00 0.00 ATOM 1141 CB CYS 186 6.948-4.924 0.416 1.00 0.00 ATOM 1142 1HB CYS 186 5.964-4.988 0.856 1.00 0.00 ATOM 1143 2HB CYS 186 7.346-5.920 0.303 1.00 0.00 ATOM 1144 QB CYS 186 6.655-5.454 0.579 1.00 0.00 ATOM 1145 SG CYS 186 6.763-4.223-1.254 1.00 0.00 ATOM 1146 C CYS 186 9.330-4.364 1.016 1.00 0.00 ATOM 1147 O CYS 186 9.824-3.847 0.023 1.00 0.00 ATOM 1148 N CYS 187 10.029-5.143 1.834 1.00 0.00 ATOM 1149 H CYS 187 9.589-5.539 2.616 1.00 0.00 ATOM 1150 CA CYS 187 11.448-5.418 1.588 1.00 0.00 ATOM 1151 HA CYS 187 11.846-4.596 1.014 1.00 0.00 ATOM 1152 CB CYS 187 12.226-5.528 2.903 1.00 0.00 ATOM 1153 1HB CYS 187 13.027-6.243 2.778 1.00 0.00 ATOM 1154 2HB CYS 187 11.562-5.874 3.680 1.00 0.00 ATOM 1155 QB CYS 187 12.294-6.058 3.229 1.00 0.00 ATOM 1156 SG CYS 187 12.966-3.961 3.466 1.00 0.00 ATOM 1157 C CYS 187 11.626-6.695 0.788 1.00 0.00 ATOM 1158 O CYS 187 10.771-7.574 0.831 1.00 0.00 ATOM 1159 N PRO 188 12.738-6.806 0.038 1.00 0.00 ATOM 1160 CD PRO 188 13.801-5.787-0.074 1.00 0.00 ATOM 1161 CA PRO 188 13.021-7.985-0.785 1.00 0.00 ATOM 1162 HA PRO 188 12.227-8. 166-1.497 1.00 0.00

ATOM 1163 CB PRO 188 14.304-7.614-1.536 1.00 0.00 ATOM 1164 1HB PRO 188 14.056-7.274-2.530 1.00 0.00 ATOM 1165 2HB PRO 188 14.947-8.482-1.598 1.00 0.00 ATOM 1166 QB PRO 188 14.501-7.878-2.064 1.00 0.00 ATOM 1167 CG PRO 188 14.932-6.530-0.729 1.00 0.00 ATOM 1168 1HG PRO 188 15.491-5.868-1.374 1.00 0.00 ATOM 1169 2HG PRO 188 15.581-6.960 0.020 1.00 0.00 ATOM 1170 QG PRO 188 15.536-6.414-0.677 1.00 0.00 ATOM 1171 1HD PRO 188 13.482-4.960-0.693 1.00 0.00 ATOM 1172 2HD PRO 188 14.101-5.433 0.901 1.00 0.00 ATOM 1173 QD PRO 188 13.791-5.196 0.104 1.00 0.00 ATOM 1174 C PRO 188 13.236-9.247 0.047 1.00 0.00 ATOM 1175 O PRO 188 14.066-9.269 0.960 1.00 0.00 ATOM 1176 N LEU 189 12.483-10.285-0.287 1.00 0. 00 ATOM 1177 H LEU 189 11.848-10.190-1.029 1.00 0.00 ATOM 1178 CA LEU 189 12.571-11.566 0.394 1.00 0.00 ATOM 1179 HA LEU 189 13.419-11.534 1.061 1.00 0.00 ATOM 1180 CB LEU 189 11.299-11.831 1.204 1.00 0.00 ATOM 1181 1HB LEU 189 10.480-11.954 0.512 1.00 0.00 ATOM 1182 2HB LEU 189 11.103-10.966 1.820 1.00 0.00 ATOM 1183 QB LEU 189 10.791-11.460 1.166 1.00 0.00 ATOM 1184 CG LEU 189 11.352-13.065 2.107 1.00 0.00 ATOM 1185 HG LEU 189 11.925-13.837 1.612 1.00 0.00 ATOM 1186 QD1 LEU 189 12.204-12.658 3.730 1.00 0.00 ATOM 1187 QD2 LEU 189 9.621-13.728 2.417 1.00 0.00 ATOM 1188 CD1 LEU 189 12.041-12.736 3.421 1.00 0.00 ATOM 1189 1HD1 LEU 189 11.519-11.926 3.907 1.00 0.00 ATOM 1190 2HD1 LEU 189 13.062-12.443 3.226 1.00 0.00 ATOM 1191 3HD1 LEU 189 12.031-13.606 4.059 1.00 0.00 ATOM 1192 CD2 LEU 189 9.952-13.602 2.358 1.00 0.00 ATOM 1193 1HD2 LEU 189 9.507-13.895 1.419 1.00 0.00 ATOM 1194 2HD2 LEU 189 9.350-12.833 2.819 1.00 0.00 ATOM 1195 3HD2 LEU 189 10.008-14.458 3.013 1.00 0.00 ATOM 1196 QQD LEU 189 10.913-13.193 3.073 1.00 0.00 ATOM 1197 C LEU 189 12.778-12.681-0.626 1.00 0.00 ATOM 1198 OT1 LEU 189 12.341-12.505-1.784 1.00 0.00 ATOM 1199 OT2 LEU 189 13.376-13.715-0.264 1.00 0.00 TER ENDMDL MODEL 6 ATOM 1 N SER 124 15.840 15.461 3.189 1.00 0.00 ATOM 2 CA SER 124 16.224 14.154 2.595 1.00 0.00 ATOM 3 HA SER 124 16.476 14.299 1.555 1.00 0.00 ATOM 4 CB SER 124 17.442 13.630 3.353 1.00 0.00 ATOM 5 1HB SER 124 18.171 13.257 2.649 1.00 0.00 ATOM 6 2HB SER 124 17.134 12.829 4.013 1.00 0.00 ATOM 7 QB SER 124 17.653 13.043 3.331 1.00 0.00 ATOM 8 OG SER 124 18.034 14.664 4.128 1.00 0.00 ATOM 9 HG SER 124 18.719 14.289 4.696 1.00 0.00 ATOM 10 C SER 124 15.068 13.178 2.704 1.00 0.00 ATOM 11 O SER 124 15.238 12.022 3.091 1.00 0.00 ATOM 12 1HT SER 124 14.858 15.418 3.546 1.00 0.00 ATOM 13 2HT SER 124 15.907 16.213 2.479 1.00 0.00 ATOM 14 3HT SER 124 16.475 15.687 3.982 1.00 0.00 ATOM 15 N ASP 125 13. 891 13.681 2.393 1.00 0. 00 ATOM 16 H ASP 125 13.833 14.620 2.120 1.00 0. 00 ATOM 17 CA ASP 125 12.665 12.918 2.477 1.00 0.00 ATOM 18 HA ASP 125 12.863 12.023 3.047 1.00 0.00 ATOM 19 CB ASP 125 11.609 13.756 3.205 1.00 0.00 ATOM 20 1HB ASP 125 11.007 13.108 3.825 1.00 0.00 ATOM 21 2HB ASP 125 10.977 14.242 2.477 1.00 0.00 ATOM 22 QB ASP 125 10.992 13.675 3.151 1.00 0.00 ATOM 23 CG ASP 125 12.233 14.825 4.092 1.00 0.00 ATOM 24 OD1 ASP 125 12. 118 14.711 5.325 1.00 0.00 ATOM 25 OD2 ASP 125 12.865 15.767 3.551 1.00 0.00 ATOM 26 C ASP 125 12.180 12.531 1.090 1.00 0.00 ATOM 27 O ASP 125 12. 669 13.054 0.087 1.00 0.00 ATOM 28 N ALA 126 11.221 11. 614 1.036 1.00 0.00 ATOM 29 H ALA 126 10.873 11.236 1.872 1.00 0.00 ATOM 30 CA ALA 126 10.672 11.152-0.233 1.00 0.00 ATOM 31 HA ALA 126 10.579 12.007-0.887 1.00 0.00 ATOM 32 QB ALA 126 11.841 9.915-1.041 1.00 0. 00

ATOM 33 CB ALA 126 11.617 10.151-0.887 1.00 0.00 ATOM 34 1HB ALA 126 11.395 9.158-0.525 1.00 0.00 ATOM 35 2HB ALA 126 12.637 10.405-0.639 1.00 0.00 ATOM 36 3HB ALA 126 11. 489 10.182-1.958 1.00 0.00 ATOM 37 C ALA 126 9.301 10.523-0.035 1.00 0.00 ATOM 38 O ALA 126 8.791 10.460 1.081 1.00 0.00 ATOM 39 N LEU 127 8.715 10.051-1.127 1.00 0.00 ATOM 40 H LEU 127 9.177 10.128-1.984 1.00 0.00 ATOM 41 CA LEU 127 7.405 9.419-1.086 1.00 0.00 ATOM 42 HA LEU 127 7.093 9.365-0.056 1.00 0.00 ATOM 43 CB LEU 127 6.397 10.253-1.876 1.00 0.00 ATOM 44 1HB LEU 127 6.448 9.945-2.909 1.00 0.00 ATOM 45 2HB LEU 127 6.689 11.291-1.812 1.00 0.00 ATOM 46 QB LEU 127 6.569 10.618-2.360 1.00 0.00 ATOM 47 CG LEU 127 4.943 10.133-1.414 1.00 0.00 ATOM 48 HG LEU 127 4.742 9.106-1.141 1.00 0.00 ATOM 49 QD1 LEU 127 4.634 11.207 0.097 1.00 0.00 ATOM 50 QD2 LEU 127 3.772 10.604-2.807 1.00 0.00 ATOM 51 CD1 LEU 127 4.693 11.001-0.193 1.00 0.00 ATOM 52 1HD1 LEU 127 4.010 10.496 0.474 1.00 0.00 ATOM 53 2HD1 LEU 127 4.264 11.943-0.503 1.00 0.00 ATOM 54 3HD1 LEU 127 5.627 11.182 0.319 1.00 0.00 ATOM 55 CD2 LEU 127 3.997 10.513-2.541 1.00 0.00 ATOM 56 1HD2 LEU 127 2.977 10.443-2.192 1.00 0.00 ATOM 57 2HD2 LEU 127 4.139 9.841-3.373 1.00 0.00 ATOM 58 3HD2 LEU 127 4.200 11.526-2.856 1.00 0.00 ATOM 59 QQD LEU 127 4.203 10.906-1.355 1.00 0.00 ATOM 60 C LEU 127 7.470 8.010-1.665 1.00 0.00 ATOM 61 O LEU 127 6.445 7.407-1.981 1.00 0.00 ATOM 62 N LEU 128 8.680 7.493-1.814 1.00 0.00 ATOM 63 H LEU 128 9.459 8.019-1.552 1.00 0.00 ATOM 64 CA LEU 128 8.871 6.162-2.365 1.00 0.00 ATOM 65 HA LEU 128 7.934 5.636-2.290 1.00 0.00 ATOM 66 CB LEU 128 9.272 6.260-3.843 1.00 0.00 ATOM 67 1HB LEU 128 10.350 6.278-3.900 1.00 0.00 ATOM 68 2HB LEU 128 8.892 7.193-4.234 1.00 0.00 ATOM 69 QB LEU 128 9.621 6.736-4.067 1.00 0.00 ATOM 70 CG LEU 128 8.764 5.122-4.735 1.00 0.00 ATOM 71 HG LEU 128 8.463 4.288-4.116 1.00 0.00 ATOM 72 QD1 LEU 128 7.262 5.680-5.717 1.00 0.00 ATOM 73 QD2 LEU 128 10.120 4.534-5.898 1.00 0.00 ATOM 74 CD1 LEU 128 7.550 5.573-5.528 1.00 0.00 ATOM 75 1HD1 LEU 128 7.177 4.747-6.116 1.00 0.00 ATOM 76 2HD1 LEU 128 7.829 6.384-6.185 1.00 0.00 ATOM 77 3HD1 LEU 128 6.779 5.908-4.849 1.00 0.00 ATOM 78 CD2 LEU 128 9.861 4.647-5.675 1.00 0.00 ATOM 79 1HD2 LEU 128 10.274 3.719-5.308 1.00 0.00 ATOM 80 2HD2 LEU 128 10.640 5. 392-5.727 1.00 0.00 ATOM 81 3HD2 LEU 128 9.446 4.. 491-6.660 1.00 0.00 ATOM 82 QQD LEU 128 8.691 5. 107-5.807 1.00 0.00 ATOM 83 C LEU 128 9.923 5.403-1.560 1.00 0.00 ATOM 84 O LEU 128 10.061 5.630-0.359 1.00 0.00 ATOM 85 N VAL 129 10.638 4.499-2.229 1.00 0.00 ATOM 86 H VAL 129 10.452 4.376-3.181 1.00 0.00 ATOM 87 CA VAL 129 11.680 3.672-1.604 1.00 0.00 ATOM 88 HA VAL 129 11. 191 2.922-1.001 1.00 0.00 ATOM 89 CB VAL 129 12. 520 2.949-2.682 1.00 0.00 ATOM 90 HB VAL 129 13.040 3.698-3.262 1.00 0.00 ATOM 91 QG1 VAL 129 13.810 1.821-1.903 1.00 0.00 ATOM 92 QG2 VAL 129 11.411 1.973-3.846 1.00 0.00 ATOM 93 CG1 VAL 129 13.562 2.036-2.053 1.00 0.00 ATOM 94 1HG1 VAL 129 13.093 1.411-1.307 1.00 0.00 ATOM 95 2HG1 VAL 129 14.331 2.636-1.586 1.00 0.00 ATOM 96 3HG1 VAL 129 14.006 1.415-2.817 1.00 0.00 ATOM 97 CG2 VAL 129 11.622 2.160-3.623 1.00 0.00 ATOM 98 1HG2 VAL 129 10.588 2.381-3.404 1.00 0.00 ATOM 99 2HG2 VAL 129 11.802 1.103-3.489 1.00 0.00 ATOM 100 3HG2 VAL 129 11.842 2.435-4.644 1.00 0.00 ATOM 101 QQG VAL 129 12.611 1.897-2.874 1.00 0.00 ATOM 102 C VAL 129 12.617 4.489-0.707 1.00 0.00 ATOM 103 O VAL 129 13.373 5.331-1.190 1.00 0.00 ATOM 104 N PRO 130 12.564 4.249 0.619 1.00 0.00

ATOM 105 CD PRO 130 11.683 3.288 1. 279 1.00 0.00 ATOM 106 CA PRO 130 13.389 4.946 1.596 1.00 0.00 ATOM 107 HA PRO 130 13.557 5.965 1. 315 1.00 0.00 ATOM 108 CB PRO 130 12.535 4.900 2. 877 1.00 0.00 ATOM 109 1HB PRO 130 12.177 5.895 3.101 1.00 0.00 ATOM 110 2HB PRO 130 13.142 4.545 3. 697 1.00 0.00 ATOM 111 QB PRO 130 12.660 5.220 3.399 1.00 0.00 ATOM 112 CG PRO 130 11.393 3.962 2. 595 1.00 0.00 ATOM 113 1HG PRO 130 10.471 4.523 2. 531 1.00 0.00 ATOM 114 2HG PRO 130 11.324 3.225 3.382 1.00 0.00 ATOM 115 QG PRO 130 10.898 3.874 2. 957 1.00 0.00 ATOM 116 1HD PRO 130 10.773 3.148 0.716 1.00 0.00 ATOM 117 2HD PRO 130 12. 185 2.344 1.435 1.00 0.00 ATOM 118 QD PRO 130 11.479 2.746 1. 076 1.00 0.00 ATOM 119 C PRO 130 14.738 4.266 1. 821 1.00 0. 00 ATOM 120 O PRO 130 15.731 4.599 1.181 1.00 0.00 ATOM 121 N ASP 131 14.749 3.322 2.748 1.00 0.00 ATOM 122 H ASP 131 13.919 3.128 3.216 1.00 0. 00 ATOM 123 CA ASP 131 15.960 2.579 3. 097 1.00 0.00 ATOM 124 HA ASP 131 16.798 3.258 3.027 1.00 0.00 ATOM 125 CB ASP 131 15.850 2.069 4.541 1.00 0.00 ATOM 126 1HB ASP 131 15.132 1.264 4.577 1.00 0.00 ATOM 127 2HB ASP 131 15.509 2. 874 5. 173 1.00 0.00 ATOM 128 QB ASP 131 15.321 2.069 4.875 1.00 0.00 ATOM 129 CG ASP 131 17.164 1.562 5.091 1.00 0.00 ATOM 130 OD1 ASP 131 18.213 1.817 4.471 1.00 0.00 ATOM 131 OD2 ASP 131 17.147 0.886 6.138 1.00 0.00 ATOM 132 C ASP 131 16.189 1.411 2.131 1.00 0.00 ATOM 133 O ASP 131 16.660 1.601 1.013 1.00 0.00 ATOM 134 N LYS+ 132 15.849 0.199 2.564 1.00 0.00 ATOM 135 H LYS+ 132 15.478 0.101 3.464 1.00 0.00 ATOM 136 CA LYS+ 132 16.022-0.986 1.723 1.00 0.00 ATOM 137 HA LYS+ 132 16.538-0.679 0.823 1.00 0.00 ATOM 138 CB LYS+ 132 16.860-2.056 2.438 1.00 0.00 ATOM 139 1HB LYS+ 132 17.397-2.626 1.693 1.00 0.00 ATOM 140 2HB LYS+ 132 16.193-2.719 2.968 1.00 0.00 ATOM 141 QB LYS+ 132 16.795-2.672 2.331 1.00 0.00 ATOM 142 CG LYS+ 132 17.869-1.500 3.432 1.00 0.00 ATOM 143 1HG LYS+ 132 17.670-0.447 3.580 1.00 0.00 ATOM 144 2HG LYS+ 132 18.863-1.627 3.030 1.00 0. 00 ATOM 145 QG LYS+ 132 18.267-1.037 3.305 1.00 0. 00 ATOM 146 CD LYS+ 132 17.781-2.215 4.773 1.00 0.00 ATOM 147 1HD LYS+ 132 17.780-3.282 4.601 1.00 0.00 ATOM 148 2HD LYS+ 132 16.862-1.927 5.263 1.00 0.00 ATOM 149 QD LYS+ 132 17.321-2.604 4.932 1.00 0.00 ATOM 150 CE LYS+ 132 18.952-1.860 5.679 1.00 0.00 ATOM 151 1HE LYS+ 132 19.783-2.509 5.443 1.00 0.00 ATOM 152 2HE LYS+ 132 18.654-2.017 6.706 1.00 0.00 ATOM 153 QE LYS+ 132 19.219-2.263 6.075 1.00 0.00 ATOM 154 NZ LYS+ 132 19.378-0.443 5.513 1.00 0.00 ATOM 155 1HZ LYS+ 132 18.606 0.203 5.822 1.00 0.00 ATOM 156 2HZ LYS+ 132 19.587-0.240 4.515 1.00 0.00 ATOM 157 3HZ LYS+ 132 20.222-0.245 6.081 1.00 0. 00 ATOM 158 QZ LYS+ 132 19.472-0.094 5.473 1.00 0. 00 ATOM 159 C LYS+ 132 14.672-1.578 1.336 1.00 0.00 ATOM 160 O LYS+ 132 14.595-2.558 0.596 1.00 0.00 ATOM 161 N CYS 133 13.608-0.980 1.844 1.00 0.00 ATOM 162 H CYS 133 13.731-0.207 2.425 1.00 0.00 ATOM 163 CA CYS 133 12.262-1.445 1.553 1.00 0.00 ATOM 164 HA CYS 133 12.322-2.489 1.284 1.00 0.00 ATOM 165 CB CYS 133 11.363-1.292 2.782 1.00 0.00 ATOM 166 1HB CYS 133 10.354-1.088 2.452 1.00 0.00 ATOM 167 2HB CYS 133 11.713-0.458 3.366 1.00 0.00 ATOM 168 QB CYS 133 11.034-0.773 2.909 1.00 0.00 ATOM 169 SG CYS 133 11.298-2.742 3.886 1. 00 0. 00 ATOM 170 C CYS 133 11.678-0.664 0.384 1.00 0.00 ATOM 171 O CYS 133 12.051 0.478 0.145 1.00 0.00 ATOM 172 N LYS+ 134 10.754-1.281-0.330 1.00 0.00 ATOM 173 H LYS+ 134 10.487-2.191-0.079 1.00 0.00 ATOM 174 CA LYS+ 134 10. 110-0.650-1.471 1. 00 0.00 ATOM 175 HA LYS+ 134 10.772 0.114-1. 852 1.00 0.00 ATOM 176 CB LYS+ 134 9.850-1.690-2. 564 1.00 0.00

ATOM 177 1HB LYS+ 134 9.034-2.323-2.247 1.00 0.00 ATOM 178 2HB LYS+ 134 10.736-2.296-2.682 1.00 0.00 ATOM 179 QB LYS+ 134 9.885-2.309-2.464 1.00 0.00 ATOM 180 CG LYS+ 134 9.497-1.096-3.918 1.00 0.00 ATOM 181 1HG LYS+ 134 10.145-0.252-4.110 1.00 0.00 ATOM 182 2HG LYS+ 134 8.469-0.765-3.900 1.00 0.00 ATOM 183 QG LYS+ 134 9.307-0.508-4.005 1.00 0.00 ATOM 184 CD LYS+ 134 9.670-2.115-5.037 1.00 0.00 ATOM 185 1HD LYS+ 134 10.282-2.930-4.677 1.00 0.00 ATOM 186 2HD LYS+ 134 10.163-1.636-5.871 1.00 0.00 ATOM 187 QD LYS+ 134 10.223-2.283-5.274 1.00 0.00 ATOM 188 CE LYS+ 134 8.332-2.670-5.511 1.00 0.00 ATOM 189 1HE LYS+ 134 8. 514-3.562-6.094 1.00 0.00 ATOM 190 2HE LYS+ 134 7.849-1.929-6.132 1.00 0.00 ATOM 191 QE LYS+ 134 8.182-2.745-6.113 1.00 0.00 ATOM 192 NZ LYS+ 134 7.430-3.010-4.372 1.00 0.00 ATOM 193 1HZ LYS+ 134 6.634-2.336-4.331 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.951-2.964-3.474 1.00 0.00 ATOM 195 3HZ LYS+ 134 7.048-3.971-4.488 1.00 0.00 ATOM 196 QZ LYS+ 134 7.211-3.090-4.098 1.00 0.00 ATOM 197 C LYS+ 134 8.805-0.009-1.032 1.00 0.00 ATOM 198 O LYS+ 134 7.852-0.706-0.701 1.00 0.00 ATOM 199 N PHE 135 8.772 1.312-1.022 1.00 0.00 ATOM 200 H PHE 135 9.569 1.814-1.294 1.00 0.00 ATOM 201 CA PHE 135 7.584 2.041-0.603 1.00 0.00 ATOM 202 HA PHE 135 7.034 1.418 0.086 1.00 0.00 ATOM 203 CB PHE 135 7.996 3.333 0.107 1.00 0.00 ATOM 204 1HB PHE 135 8.439 4.001-0.618 1.00 0.00 ATOM 205 2HB PHE 135 8.731 3.099 0.860 1.00 0.00 ATOM 206 QB PHE 135 8.585 3.550 0.121 1.00 0.00 ATOM 207 QD PHE 135 6.753 4.156 0.860 1.00 0.00 ATOM 208 QE PHE 135 4.943 5.380 1.987 1. 00 0.00 ATOM 209 QR PHE 135 5.485 5.013 1.649 1. 00 0.00 ATOM 210 CG PHE 135 6.875 4.072 0.783 1.00 0.00 ATOM 211 CD1 PHE 135 6.921 5.452 0.899 1.00 0.00 ATOM 212 1HD PHE 135 7.762 5.991 0.488 1.00 0.00 ATOM 213 CE1 PHE 135 5.906 6.143 1.531 1.00 0.00 ATOM 214 1HE PHE 135 5.953 7.218 1.615 1.00 0.00 ATOM 215 CZ PHE 135 4.831 5.456 2.055 1.00 0.00 ATOM 216 HZ PHE 135 4.032 5.993 2.552 1.00 0.00 ATOM 217 CE2 PHE 135 4.774 4.082 1. 946 1.00 0.00 ATOM 218 2HE PHE 135 3.933 3.542 2.359 1.00 0.00 ATOM 219 CD2 PHE 135 5.791 3.397 1.314 1.00 0.00 ATOM 220 2HD PHE 135 5.744 2.321 1.232 1.00 0.00 ATOM 221 C PHE 135 6.703 2.357-1.797 1.00 0.00 ATOM 222 O PHE 135 7.076 3.139-2.672 1.00 0.00 ATOM 223 N LEU 136 5.535 1.735-1.827 1.00 0.00 ATOM 224 H LEU 136 5.299 1.120-1.096 1.00.0.00 ATOM 225 CA LEU 136 4.591 1.938-2.907 1.00 0.00 ATOM 226 HA LEU 136 5.108 2.449-3.705 1.00 0.00 ATOM 227 CB LEU 136 4.058 0.599-3.431 1.00 0.00 ATOM 228 1HB LEU 136 3.409 0.803-4.271 1.00 0.00 ATOM 229 2HB LEU 136 3.467 0.145-2.648 1.00 0.00 ATOM 230 QB LEU 136 3.438 0.474-3.459 1.00 0.00 ATOM 231 CG LEU 136 5.120-0.412-3.879 1.00 0.00 ATOM 232 HG LEU 136 5.596-0.834-3.006 1.00 0.00 ATOM 233 QD1 LEU 136 4.318-1.811-4.844 1.00 0.00 ATOM 234 QD2 LEU 136 6.442 0.422-4.924 1.00 0.00 ATOM 235 CD1 LEU 136 4.473-1.544-4.659 1.00 0.00 ATOM 236 lHDl LEU 136 3.434-1.307-4.839 1.00 0.00 ATOM 237 2HD1 LEU 136 4.538-2.459-4.089 1.00 0.00 ATOM 238 3HD1 LEU 136 4.981-1.669-5.604 1.00 0.00 ATOM 239 CD2 LEU 136 6.189 0.262-4.725 1.00 0.00 ATOM 240 1HD2 LEU 136 5.970 0.108-5.771 1.00 0.00 ATOM 241 2HD2 LEU 136 7.153-0.163-4.490 1.00 0.00 ATOM 242 3HD2 LEU 136 6.201 1.321-4.511 1.00 0.00 ATOM 243 QQD LEU 136 5.380-0.694-4.884 1.00 0.00 ATOM 244 C LEU 136 3.437 2.804-2.435 1.00 0.00 ATOM 245 O LEU 136 2.363 2.300-2.113 1.00 0.00 ATOM 246 N HIS+ 137 3.660 4.108-2.405 1.00 0.00 ATOM 247 H HIS+ 137 4.535 4.452-2.679 1.00 0.00 ATOM 248 CA HIS+ 137 2.627 5.041-1. 988 1.00 0.00

ATOM 249 HA HIS+ 137 1.933 4.508-1.349 1.00 0.00 ATOM 250 CB HIS+ 137 3.239 6.225-1.214 1.00 0.00 ATOM 251 1HB HIS+ 137 3.986 6.699-1.835 1.00 0.00 ATOM 252 2HB HIS+ 137 3.714 5.850-0.319 1.00 0.00 ATOM 253 QB HIS+ 137 3.850 6.275-1.077 1.00 0.00 ATOM 254 CG HIS+ 137 2.248 7.283-0.795 1.00 0.00 ATOM 255 ND1 HIS+ 137 1. 993 7.603 0.521 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.452 8.100-1.532 1.00 0.00 ATOM 257 1HD HIS+ 137 2.395 7.168 1.314 1.00 0.00 ATOM 258 CE1 HIS+ 137 1.089 8.564 0.572 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.738 8.886-0.660 1.00 0.00 ATOM 260 2HD HIS+ 137 1.390 8.127-2.612 1.00 0.00 ATOM 261 1HE HIS+ 137 0.698 9.012 1.475 1.00 0.00 ATOM 262 2HE HIS+ 137-0.100 9.364-0.894 1.00 0.00 ATOM 263 C HIS+ 137 1.897 5.539-3.225 1.00 0.00 ATOM 264 O HIS+ 137 2.440 6.329-4.001 1. 00 0. 00 ATOM 265 N GLN 138 0.676 5.069-3.420 1.00 0.00 ATOM 266 H GLN 138 0.294 4.432-2.774 1.00 0.00 ATOM 267 CA GLN 138-0.109 5.471-4.575 1.00 0. 00 ATOM 268 HA GLN 138 0.275 6.421-4.919 1.00 0.00 ATOM 269 CB GLN 138 0.030 4.443-5.701 1.00 0.00 ATOM 270 1HB GLN 138-0.819 4.535-6.362 1.00 0.00 ATOM 271 2HB GLN 138 0.032 3.454-5.269 1.00 0.00 ATOM 272 QB GLN 138-0.393 3.995-5.815 1.00 0.00 ATOM 273 CG GLN 138 1.298 4.608-6.525 1.00 0.00 ATOM 274 1HG GLN 138 1.801 5.512-6.212 1. 00 0.00 ATOM 275 2HG GLN 138 1.028 4.690-7.567 1.00 0.00 ATOM 276 QG GLN 138 1.415 5.101-6.889 1.00 0.00 ATOM 277 CD GLN 138 2.254 3.442-6.365 1.00 0.00 ATOM 278 OE1 GLN 138 1.927 2.310-6.712 1.00 0.00 ATOM 279 NE2 GLN 138 3.441 3.710-5.837 1.00 0.00 ATOM 280 1HE2 GLN 138 3.639 4.636-5.580 1.00 0.00 ATOM 281 2HE2 GLN 138 4.073 2.971-5.728 1.00 0.00 ATOM 282 QE2 GLN 138 3.856 3.804-5.654 1.00 0.00 ATOM 283 C GLN 138-1.572 5.641-4.202 1.00 0.00 ATOM 284 O GLN 138-2.141 4.826-3.474 1.00 0. 00 ATOM 285 N GLU 139-2.174 6.703-4.709 1.00 0. 00 ATOM 286 H GLU 139-1.666 7.311-5.282 1. 00 0.00 ATOM 287 CA GLU 139-3.571 6.989-4.437 1.00 0.00 ATOM 288 HA GLU 139-3.856 6.436-3.554 1.00 0.00 ATOM 289 CB GLU 139-3.762 8.485-4.171 1.00 0.00 ATOM 290 1HB GLU 139-4.599 8.615-3.498 1.00 0.00 ATOM 291 2HB GLU 139-3.983 8.980-5.104 1.00 0.00 ATOM 292 QB GLU 139-4.291 8.798-4.301 1.00 0. 00 ATOM 293 CG GLU 139.-2. 547 9.159-3.548 1.00 0.00 ATOM 294 1HG GLU 139-2. 418 10. 131-4. 001 1.00 0.00 ATOM 295 2HG GLU 139-1.675 8.553-3.742 1.00 0.00 ATOM 296 QG GLU 139-2.046 9.342-3.871 1.00 0.00 ATOM 297 CD GLU 139-2.684 9.338-2.051 1.00 0.00 ATOM 298 OE1 GLU 139-1.694 9.749-1.412 1.00 0.00 ATOM 299 OE2 GLU 139-3.779 9.061-1.516 1.00 0.00 ATOM 300 C GLU 139-4.446 6.541-5.604 1.00 0.00 ATOM 301 0 GLU 139-4.458 7.168-6.665 1.00 0.00 ATOM 302 N ARG+ 140-5.182 5.456-5.403 1.00 0.00 ATOM 303 H ARG+ 140-5.138 5.002-4.533 1.00 0.00 ATOM 304 CA ARG+ 140-6. 067 4.929-6.433 1.00 0.00 ATOM 305 HA ARG+ 140-5.700 5.263-7.392 1.00 0.00 ATOM 306 CB ARG+ 140-6.082 3.393-6.401 1.00 0.00 ATOM 307 1HB ARG+ 140-6.564 3.071-5.486 1.00 0.00 ATOM 308 2HB ARG+ 140-5.065 3.032-6.407 1.00 0.00 ATOM 309 QB ARG+ 140-5.814 3.052-5.946 1.00 0.00 ATOM 310 CG ARG+ 140-6.823 2.756-7.570 1.00 0.00 ATOM 311 1HG ARG+ 140-7.680 3.368-7.814 1.00 0.00 ATOM 312 2HG ARG+ 140-7.157 1.772-7.276 1.00 0.00 ATOM 313 QG ARG+ 140-7.418 2.570-7.545 1.00 0.00 ATOM 314 CD ARG+ 140-5.939 2.629-8.799 1.00 0.00 ATOM 315 1HD ARG+ 140-5.626 1.599-8.896 1.00 0.00 ATOM 316 2HD ARG+ 140-5.071 3.259-8.669 1.00 0.00 ATOM 317 QD ARG+ 140-5.348 2.429-8.782 1.00 0.00 ATOM 318 NE ARG+ 140-6.640 3.031-10.019 1.00 0.00 ATOM 319 HE ARG+ 140-7.621 3.155-9.963 1.00 0.00 ATOM 320 CZ ARG+ 140-6. 033 3.248-11.186 1.00 0.00

ATOM 321 NH1 ARG+ 140-4.723 3.060-11.299 1.00 0.00 ATOM 322 1HH1 ARG+ 140-4.192 2.755-10.508 1.00 0.00 ATOM 323 2HH1 ARG+ 140-4.264 3.221-12.173 1.00 0.00 ATOM 324 QH1 ARG+ 140-4.228 2.988-11.340 1.00 0.00 ATOM 325 NH2 ARG+ 140-6.739 3.644-12.235 1.00 0.00 ATOM 326 1HH2 ARG+ 140-7.741 3.783-12.144 1.00 0.00 ATOM 327 2HH2 ARG+ 140-6.295 3.811-13.113 1.00 0.00 ATOM 328 QH2 ARG+ 140-7.018 3.797-12.628 1.00 0.00 ATOM 329 C ARG+ 140-7.475 5.466-6.224 1.00 0.00 ATOM 330 O ARG+ 140-8.298 4.830-5.569 1.00 0.00 ATOM 331 N MET 141-7. 753 6.640-6.781 1.00 0.00 ATOM 332 H MET 141-7. 057 7.103-7.292 1.00 0.00 ATOM 333 CA MET 141-9.070 7.258-6.644 1.00 0.00 ATOM 334 HA MET 141-9.368 7.165-5.610 1.00 0.00 ATOM 335 CB MET 141-9.001 8.745-7.007 1.00 0.00 ATOM 336 1HB MET 141-9.204 8.853-8.064 1.00 0.00 ATOM 337 2HB MET 141-8.007 9.111-6.800 1.00 0.00 ATOM 338 QB MET 141-8.605 8.982-7.432 1.00 0.00 ATOM 339 CG MET 141-9.996 9.603-6.242 1.00 0.00 ATOM 340 1HG MET 141-9. 686 9.655-5.209 1.00 0.00 ATOM 341 2HG MET 141-10.969 9.137-6.303 1.00 0.00 ATOM 342 QG MET 141-10.327 9.396-5.756 1.00 0.00 ATOM 343 SD MET 141-10.120 11.278-6.894 1.00 0.00 ATOM 344 QE MET 141-8.320 12.159-6.110 1.00 0.00 ATOM 345 CE MET 141-8.622 12.011-6.241 1.00 0.00 ATOM 346 1HE MET 141-7.821 11.287-6.278 1.00 0.00 ATOM 347 2HE MET 141-8.786 12.315-5.218 1.00 0.00 ATOM 348 3HE MET 141-8.355 12.873-6.835 1.00 0.00 ATOM 349 C MET 141-10.110 6.551-7.518 1.00 0.00 ATOM 350 O MET 141-10.966 7.192-8.126 1.00 0.00 ATOM 351 N ASP 142-10.032 5.228-7.552 1.00 0.00 ATOM 352 H ASP 142-9.332 4.785-7.027 1.00 0.00 ATOM 353 CA ASP 142-10. 950 4.409-8.323 1.00 0.00 ATOM 354 HA ASP 142-11.662 5.060-8.809 1.00 0.00 ATOM 355 CB ASP 142-10.188 3.615-9.383 1.00 0.00 ATOM 356 1HB ASP 142-10.703 2.682-9.560 1.00 0.00 ATOM 357 2HB ASP 142-9.193 3.409-9.024 1.00 0.00 ATOM 358 QB ASP 142-9.948 3.046-9.292 1.00 0.00 ATOM 359 CG ASP 142-10.078 4.353-10.694 1.00 0.00 ATOM 360 OD1 ASP 142-9.188 3.999-11.492 1.00 0.00 ATOM 361 OD2 ASP 142-10.872 5.282-10.922 1.00 0.00 ATOM 362 C ASP 142-11.684 3.439-7.416 1.00 0.00 ATOM 363 O ASP 142-12.913 3.438-7.341 1.00 0.00 ATOM 364 N VAL 143-10.916 2.605-6.733 1.00 0.00 ATOM 365 H VAL 143-9. 944 2.655-6.842 1.00 0.00 ATOM 366 CA VAL 143-11.477 1.603-5.843 1.00 0.00 ATOM 367 HA VAL 143-12.474 1.372-6.189 1.00 0.00 ATOM 368 CB VAL 143-10.635 0.308-5.881 1.00 0.00 ATOM 369 HB VAL 143-9.919 0.345-5.070 1.00 0.00 ATOM 370 QG1 VAL 143-11.721-1.198-5.629 1.00 0.00 ATOM 371 QG2 VAL 143-9.685 0.162-7.500 1.00 0.00 ATOM 372 CG1 VAL 143-11.515-0.909-5.676 1.00 0.00 ATOM 373 1HG1 VAL 143-12.063-0.808-4.753 1.00 0.00 ATOM 374 2HG1 VAL 143-10.895-1.792-5.634 1.00 0.00 ATOM 375 3HG1 VAL 143-12.206-0.994-6. 501 1.00 0.00 ATOM 376 CG2 VAL 143-9.866 0.190-7.190 1.00 0.00 ATOM 377 1HG2 VAL 143-10.001-0.801-7.598 1.00 0.00 ATOM 378 2HG2 VAL 143-8.817 0.365-7.008 1.00 0.00 ATOM 379 3HG2 VAL 143-10.238 0.922-7. 894 1.00 0.00 ATOM 380 QQG VAL 143-10.703-0.518-6.565 1.00 0.00 ATOM 381 C VAL 143-11.555 2.125-4.409 1.00 0.00 ATOM 382 O VAL 143-10.713 2.906-3. 979 1.00 0.00 ATOM 383 N CYS 144-12.578 1.696-3. 678 1. 00 0.00 ATOM 384 H CYS 144-13.223 1.074-4. 078 1.00 0.00 ATOM 385 CA CYS 144-12.772 2.127-2.295 1.00 0.00 ATOM 386 HA CYS 144-11.839 2.540-1. 932 1.00 0.00 ATOM 387 CB CYS 144-13.855 3.200-2.223 1.00 0.00 ATOM 388 1HB CYS 144-14.794 2.733-1. 963 1.00 0.00 ATOM 389 2HB CYS 144-13.949 3.672-3.189 1.00 0.00 ATOM 390 QB CYS 144-14.371 3.203-2. 576 1.00 0.00 ATOM 391 SG CYS 144-13.527 4.507-0.998 1.00 0.00 ATOM 392 C CYS 144-13.161 0.955-1. 416 1.00 0.00

ATOM 393 O CYS 144-14.313 0.528-1.425 1.00 0.00 ATOM 394 N GLU 145-12.200 0.435-0.665 1.00 0.00 ATOM 395 H GLU 145-11.298 0.815-0.704 1.00 0.00 ATOM 396 CA GLU 145-12.449-0.697 0.206 1.00 0.00 ATOM 397 HA GLU 145-13.512-0.869 0.223 1.00 0.00 ATOM 398 CB GLU 145-11.771-1.934-0.356 1.00 0.00 ATOM 399 1HB GLU 145-11.485-2.580 0.459 1.00 0.00 ATOM 400 2HB GLU 145-10.883-1.634-0.895 1.00 0.00 ATOM 401 QB GLU 145-11.184-2.107-0.218 1.00 0.00 ATOM 402 CG GLU 145-12.683-2.714-1.285 1.00 0.00 ATOM 403 1HG GLU 145-12.253-3.688-1.466 1.00 0.00 ATOM 404 2HG GLU 145-12.777-2.178-2.218 1.00 0.00 ATOM 405 QG GLU 145-12.515-2.933-1.842 1.00 0.00 ATOM 406 CD GLU 145-14.057-2.890-0.681 1.00 0.00 ATOM 407 OE1 GLU 145-14.142-3.428 0.441 1.00 0.00 ATOM 408 OE2 GLU 145-15.045-2.449-1.292 1.00 0.00 ATOM 409 C GLU 145-11.974-0.442 1.622 1.00 0.00 ATOM 410 0 GLU 145-11. 415 0.613 1.927 1.00 0.00 ATOM 411 N THR 146-12.212-1.420 2.481 1.00 0.00 ATOM 412 H THR 146-12. 666-2.229 2.162 1.00 0.00 ATOM 413 CA THR 146-11.831-1.333 3.878 1.00 0.00 ATOM 414 HA THR 146-12.128-0.361 4.245 1.00 0.00 ATOM 415 CB THR 146-12.567-2.413 4.673 1.00 0.00 ATOM 416 HB THR 146-11.962-3.308 4.689 1.00 0.00 ATOM 417 QG2 THR 146-12.924-1.927 6.451 1.00 0.00 ATOM 418 OG1 THR 146-13.804-2.724 4.054 1.00 0.00 ATOM 419 1HG THR 146-14.504-2.717 4.714 1.00 0.00 ATOM 420 CG2 THR 146-12.855-2.022 6.107 1.00 0.00 ATOM 421 1HG2 THR 146-13.280-1.027 6.134 1.00 0.00 ATOM 422 2HG2 THR 146-11.938-2.034 6.677 1.00 0.00 ATOM 423 3HG2 THR 146-13.554-2.722 6.541 1.00 0.00 ATOM 424 C THR 146-10.319-1.481 4.038 1.00 0.00 ATOM 425 O THR 146-9.624-1.907 3.112 1.00 0.00 ATOM 426 N HIS+ 147-9.824-1.128 5.221 1.00 0.00 ATOM 427 H HIS+ 147-10.441-0.797 5.910 1.00 0.00 ATOM 428 CA HIS+ 147-8.398-1.210 5.533 1.00 0.00 ATOM 429 HA HIS+ 147-7.876-0.509 4.898 1.00 0.00 ATOM 430 CB HIS+ 147-8.168-0.822 6.996 1.00 0.00 ATOM 431 1HB HIS+ 147-8.093-1.723 7.590 1.00 0.00 ATOM 432 2HB HIS+ 147-9.010-0.241 7.343 1.00 0.00 ATOM 433 QB HIS+ 147-8.551-0.982 7.467 1.00 0.00 ATOM 434 CG HIS+ 147-6.929-0.015 7.226 1.00 0.00 ATOM 435 ND1 HIS+ 147-6.930 1.361 7.297 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.643-0.400 7.412 1.00 0.00 ATOM 437 1HD HIS+ 147-7.718 1.943 7.192 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.700 1.790 7.518 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.898 0.742 7.594 1.00 0.00 ATOM 440 2HD HIS+ 147-5.268-1.416 7.397 1.00 0.00 ATOM 441 1HE HIS+ 147-5.400 2.823 7.619 1.00 0.00 ATOM 442 2HE HIS+ 147-3.917 0.784 7.582 1.00 0.00 ATOM 443 C HIS+ 147-7.843-2.613 5.286 1.00 0.00 ATOM 444 O HIS+ 147-6.681-2.774 4.916 1.00 0.00 ATOM 445 N LEU 148-8.679-3.623 5.500 1.00 0.00 ATOM 446 H LEU 148-9.591-3.432 5.797 1.00 0.00 ATOM 447 CA LEU 148-8.272-5.009 5.312 1.00 0.00 ATOM 448 HA LEU 148-7.322-5.143 5.806 1.00 0.00 ATOM 449 CB LEU 148-9.299-5.947 5.955 1.00 0.00 ATOM 450 1HB LEU 148-10.282-5.656 5.617 1.00 0.00 ATOM 451 2HB LEU 148-9.252-5.817 7.027 1.00 0.00 ATOM 452 QB LEU 148-9.767-5.736 6.322 1.00 0.00 ATOM 453 CG LEU 148-9.109-7.432 5.644 1.00 0.00 ATOM 454 HG LEU 148-8.706-7.533 4.647 1.00 0.00 ATOM 455 QD1 LEU 148-7.891-8.213 6.844 1.00 0.00 ATOM 456 QD2 LEU 148-10.757-8.335 5.701 1.00 0.00 ATOM 457 CD1 LEU 148-8.124-8.063 6.614 1.00 0.00 ATOM 458 1HD1 LEU 148-8.655-8.717 7.291 1.00 0.00 ATOM 459 2HD1 LEU 148-7.626-7.289 7.178 1.00 0.00 ATOM 460 3HD1 LEU 148-7.392-8.635 6.062 1.00 0.00 ATOM 461 CD2 LEU 148-10.442-8.161 5.690 1.00 0.00 ATOM 462 1HD2 LEU 148-10.281-9.215 5.511 1.00 0.00 ATOM 463 2HD2 LEU 148-11.097-7.763 4.930 1.00 0.00 ATOM 464 3HD2 LEU 148-10.893-8.027 6.662 1. 00 0. 00

ATOM 465 QQD LEU 148-9.324-8.274 6.272 1.00 0.00 ATOM 466 C LEU 148-8.105-5.350 3.833 1.00 0.00 ATOM 467 O LEU 148-7.172-6.061 3.458 1.00 0.00 ATOM 468 N HIS+ 149-9.009-4.850 2.996 1.00 0.00 ATOM 469 H HIS+ 149-9.733-4.292 3.346 1.00 0.00 ATOM 470 CA HIS+ 149-8.944-5.126 1.565 1.00 0.00 ATOM 471 HA HIS+ 149-8.932-6.200 1.451 1.00 0.00 ATOM 472 CB HIS+ 149-10.171-4.576 0.840 1.00 0.00 ATOM 473 1HB HIS+ 149-9.852-3.952 0.017 1.00 0.00 ATOM 474 2HB HIS+ 149-10.760-3.984 1.525 1.00 0.00 ATOM 475 QB HIS+ 149-10.306-3.968 0.771 1.00 0.00 ATOM 476 CG HIS+ 149-11.046-5.660 0.286 1.00 0.00 ATOM 477 ND1 HIS+ 149-12.413-5.538 0.148 1.00 0.00 ATOM 478 CD2 HIS+ 149-10.737-6.901-0.162 1.00 0.00 ATOM 479 1HD HIS+ 149-12.952-4.735 0.372 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.905-6.656-0.358 1.00 0.00 ATOM 481 NE2 HIS+ 149-11.909-7.498-0.556 1.00 0.00 ATOM 482 2HD HIS+ 149-9.749-7.340-0.202 1.00 0.00 ATOM 483 1HE HIS+ 149-13.947-6.844-0.577 1.00 0.00 ATOM 484 2HE HIS+ 149-11.980-8.349-1.037 1.00 0.00 ATOM 485 C HIS+ 149-7.662-4.576 0.959 1.00 0.00 ATOM 486 O HIS+ 149-6.934-5.305 0.288 1.00 0.00 ATOM 487 N TRP 150-7. 374-3.303 1.210 1.00 0.00 ATOM 488 H TRP 150-7. 989-2.770 1.761 1.00 0.00 ATOM 489 CA TRP 150-6. 153-2.686 0.692 1.00 0.00 ATOM 490 HA TRP 150-6. 142-2.806-0.382 1.00 0.00 ATOM 491 CB TRP 150-6. 093-1.203 1.038 1.00 0.00 ATOM 492 1HB TRP 150-5. 113-0.825 0.782 1.00 0.00 ATOM 493 2HB TRP 150-6.248-1.084 2.100 1.00 0.00 ATOM 494 QB TRP 150-5.680-0.954 1.441 1.00 0.00 ATOM 495 CG TRP 150-7.108-0.363 0.331 1.00 0.00 ATOM 496 CD1 TRP 150-7. 501 0.891 0.683 1.00 0.00 ATOM 497 CD2 TRP 150-7.855-0.703-0.845 1.00 0.00 ATOM 498 CE3 TRP 150-7.912-1.826-1.677 1.00 0.00 ATOM 499 CE2 TRP 150-8.678 0.395-1.139 1.00 0.00 ATOM 500 NE1 TRP 150-8. 445 1.351-0.194 1.00 0.00 ATOM 501 HD TRP 150-7.117 1.433 1.536 1.00 0.00 ATOM 502 3HE TRP 150-7.298-2.691-1.489 1.00 0.00 ATOM 503 CZ3 TRP 150-8.771-1.814-2.752 1.00 0.00 ATOM 504 CZ2 TRP 150-9. 540 0.405-2.224 1.00 0.00 ATOM 505 1HE TRP 150-8.883 2.226-0.150 1.00 0.00 ATOM 506 3HZ TRP 150-8.832-2.673-3.402 1.00 0.00 ATOM 507 CH2 TRP 150-9.574-0.704-3.016 1.00 0.00 ATOM 508 2HZ TRP 150-10. 170 1.256-2.446 1.00 0.00 ATOM 509 HH TRP 150-10.235-0.739-3.869 1.00 0.00 ATOM 510 C TRP 150-4. 931-3.376 1.252 1.00 0.00 ATOM 511 O TRP 150-3. 925-3.492 0.570 1.00 0.00 ATOM 512 N HIS+ 151-5.029-3.849 2.488 1.00 0.00 ATOM 513 H HIS+ 151-5.869-3.735 2.982 1.00 0.00 ATOM 514 CA HIS+ 151-3.923-4.553 3.113 1.00 0.00 ATOM 515 HA HIS+ 151-3.071-3.891 3.131 1.00 0.00 ATOM 516 CB HIS+ 151-4.286-4.961 4.550 1.00 0.00 ATOM 517 1HB HIS+ 151-5.130-5.637 4.517 1.00 0.00 ATOM 518 2HB HIS+ 151-4.565-4.078 5.104 1.00 0.00 ATOM 519 QB HIS+ 151-4.847-4.857 4.811 1.00 0.00 ATOM 520 CG HIS+ 151-3.178-5. 644 5.303 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.773-5.258 6.563 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.398-6.703 4.971 1.00 0.00 ATOM 523 1HD HIS+ 151-3.147-4.515 7.084 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.793-6.048 6.969 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.549-6.932 6.022 1.00 0.00 ATOM 526 2HD HIS+ 151-2. 434-7.255 4.038 1.00 0.00 ATOM 527 1HE HIS+ 151-1.270-5.973 7.912 1.00 0.00 ATOM 528 2HE HIS+ 151-0.925-7.684 6. 099 1.00 0.00 ATOM 529 C HIS+ 151-3.584-5.783 2.281 1.00 0.00 ATOM 530 O HIS+ 151-2.420-6.036 1.977 1.00 0.00 ATOM 531 N THR 152-4.615-6.532 1.910 1.00 0.00 ATOM 532 H THR 152-5.518-6.266 2.180 1.00 0.00 ATOM 533 CA THR 152-4.440-7.729 1.104 1.00 0.00 ATOM 534 HA THR 152-3.697-8.347 1.587 1.00 0.00 ATOM 535 CB THR 152-5.754-8.512 1.011 1.00 0.00 ATOM 536 HB THR 152-6. 352-8.097 0.212 1.00 0.00

ATOM 537 QG2 THR 152-5.505-10.334 0.652 1.00 0.00 ATOM 538 OG1 THR 152-6.493-8.417 2.220 1.00 0.00 ATOM 539 1HG THR 152-6.609-7.492 2.463 1.00 0.00 ATOM 540 CG2 THR 152-5.554-9.984 0.721 1.00 0.00 ATOM 541 1HG2 THR 152-5.695-10.551 1.629 1.00 0.00 ATOM 542 2HG2 THR 152-4.552-10.145 0.348 1.00 0.00 ATOM 543 3HG2 THR 152-6.270-10.306-0.020 1.00 0.00 ATOM 544 C THR 152-3.932-7.377-0.288 1.00 0.00 ATOM 545 O THR 152-2.973-7.970-0.756 1.00 0.00 ATOM 546 N VAL 153-4.560-6.401-0.940 1.00 0.00 ATOM 547 H VAL 153-5.317-5.940-0.513 1.00 0.00 ATOM 548 CA VAL 153-4.129-5.993-2.275 1.00 0.00 ATOM 549 HA VAL 153-4.199-6.851-2.921 1.00 0.00 ATOM 550 CB VAL 153-5.019-4.867-2.850 1.00 0.00 ATOM 551 HB VAL 153-4.899-3.989-2.233 1.00 0. 00 ATOM 552 QG1 VAL 153-4.500-4.426-4.605 1.00 0.00 ATOM 553 QG2 VAL 153-6.830-5.370-2.813 1.00 0.00 ATOM 554 CG1 VAL 153-4.600-4.511-4.269 1.00 0.00 ATOM 555 1HG1 VAL 153-3.580-4.828-4.435 1.00 0.00 ATOM 556 2HG1 VAL 153-4.672-3.442-4.409 1.00 0.00 ATOM 557 3HG1 VAL 153-5.250-5.010-4.972 1.00 0.00 ATOM 558 CG2 VAL 153-6. 484-5.274-2.820 1.00 0.00 ATOM 559 1HG2 VAL 153-7.070-4.551-3.368 1.00 0.00 ATOM 560 2HG2 VAL 153-6.826-5.314-1.796 1.00 0.00 ATOM 561 3HG2 VAL 153-6.596-6.247-3.276 1.00 0.00 ATOM 562 QQG VAL 153-5.665-4.898-3.709 1.00 0.00 ATOM 563 C VAL 153-2.678-5.539-2.242 1.00 0.00 ATOM 564 O VAL 153-1.866-5.965-3.059 1.00 0.00 ATOM 565 N ALA 154-2.365-4.690-1.279 1.00 0.00 ATOM 566 H ALA 154-3.070-4.403-0.652 1.00 0.00 ATOM 567 CA ALA 154-1.013-4.182-1.106 1.00 0.00 ATOM 568 HA ALA 154-0. 730-3.650-2.003 1.00 0.00 ATOM 569 QB ALA 154-0.965-2.983 0.337 1.00 0.00 ATOM 570 CB ALA 154-0.975-3.213 0.060 1.00 0.00 ATOM 571 1HB ALA 154-0.515-3.693 0.911 1.00 0.00 ATOM 572 2HB ALA 154-1.982-2.915 0.315 1.00 0.00 ATOM 573 3HB ALA 154-0.400-2.341-0.216 1.00 0.00 ATOM 574 C ALA 154-0.021-5.312-0.870 1.00 0.00 ATOM 575 O ALA 154 1.000-5.411-1.556 1.00 0.00 ATOM 576 N LYS+ 155-0.324-6.158 0.109 1.00 0.00 ATOM 577 H LYS+ 155-1.152-6.020 0.620 1.00 0.00 ATOM 578 CA LYS+ 155 0.540-7.280 0.447 1.00 0.00 ATOM 579 HA LYS+ 155 1.514-6.883 0.713 1.00 0.00 ATOM 580 CB LYS+ 155-0.026-8.065 1.634 1.00 0.00 ATOM 581 1HB LYS+ 155-0. 872-8.647 1.292 1.00 0.00 ATOM 582 2HB LYS+ 155-0.364-7.366 2.384 1.00 0.00 ATOM 583 QB LYS+ 155-0.618-8.006 1.838 1.00 0.00 ATOM 584 CG LYS+ 155 0.976-9.013 2.278 1.00 0.00 ATOM 585 1HG LYS+ 155 1.358-8.558 3.180 1.00 0.00 ATOM 586 2HG LYS+ 155 1.787-9.186 1.587 1.00 0.00 ATOM 587 QG LYS+ 155 1.573-8.872 2.384 1.00 0.00 ATOM 588 CD LYS+ 155 0.335-10.349 2.629 1.00 0.00 ATOM 589 1HD LYS+ 155-0.706-10.323 2.339 1.00 0.00 ATOM 590 2HD LYS+ 155 0.410-10.504 3.696 1.00 0.00 ATOM 591 QD LYS+ 155-0.148-10.413 3.018 1.00 0.00 ATOM 592 CE LYS+ 155 1.021-11.504 1.911 1.00 0.00 ATOM 593 1HE LYS+ 155 1.550-12.101 2.640 1.00 0.00 ATOM 594 2HE LYS+ 155 1.728-11.100 1.200 1.00 0.00 ATOM 595 QE LYS+ 155 1.639-11.600 1.920 1.00 0. 00 ATOM 596 NZ LYS+ 155 0.051-12.369 1.186 1.00 0.00 ATOM 597 1HZ LYS+ 155-0.318-13.109 1.809 1.00 0.00 ATOM 598 2HZ LYS+ 155 0.508-12.815 0.364 1.00 0.00 ATOM 599 3HZ LYS+ 155-0.756-11.793 0.832 1.00 0.00 ATOM 600 QZ LYS+ 155-0. 188-12. 572 1.002 1.00 0.00 ATOM 601 C LYS+ 155 0.713-8.198-0.745 1.00 0.00 ATOM 602 O LYS+ 155 1.836-8.545-1.086 1.00 0. 00 ATOM 603 N GLU 156-0. 393-8.588-1.370 1.00 0.00 ATOM 604 H GLU 156-1.273-8.281-1.043 1.00 0.00 ATOM 605 CA GLU 156-0.338-9.471-2.526 1.00 0.00 ATOM 606 HA GLU 156 0.113-10.398-2.204 1.00 0.00 ATOM 607 CB GLU 156-1.743-9.772-3.051 1.00 0.00 ATOM 608 1HB GLU 156-1.655-10.262-4.010 1.00 0.00

ATOM 609 2HB GLU 156-2.272-8.840-3.182 1.00 0.00 ATOM 610 QB GLU 156-1. 963-9.551-3.596 1.00 0.00 ATOM 611 CG GLU 156-2. 570-10. 668-2. 131 1.00 0.00 ATOM 612 1HG GLU 156-3.043-11.429-2.729 1.00 0.00 ATOM 613 2HG GLU 156-3.330-10.065-1.657 1.00 0.00 ATOM 614 QG GLU 156-3.186-10.747-2.193 1.00 0.00 ATOM 615 CD GLU 156-1.752-11.342-1.048 1.00 0.00 ATOM 616 OE1 GLU 156-1.937-10.999 0.139 1.00 0.00 ATOM 617 OE2 GLU 156-0.915-12.208-1.376 1.00 0.00 ATOM 618 C GLU 156 0.527-8.877-3.634 1.00 0.00 ATOM 619 0 GLU 156 1.352-9.572-4.202 1.00 0.00 ATOM 620 N THR 157 0.349-7.590-3.926 1.00 0.00 ATOM 621 H THR 157-0.324-7.073-3.429 1.00 0.00 ATOM 622 CA THR 157 1.142-6.925-4.966 1.00 0.00 ATOM 623 HA THR 157 0.929-7.417-5.904 1.00 0.00 ATOM 624 CB THR 157 0.745-5.447-5.078 1.00 0.00 ATOM 625 HB THR 157 1.005-4.944-4.156 1.00 0. 00 ATOM 626 QG2 THR 157 1.595-4.544-6.483 1.00 0.00 ATOM 627 OG1 THR 157-0.650-5.314-5.280 1.00 0.00 ATOM 628 1HG THR 157-1. 122-5.640-4.501 1.00 0.00 ATOM 629 CG2 THR 157 1.432-4.717-6.213 1.00 0.00 ATOM 630 1HG2 THR 157 1.879-5.437-6.884 1.00 0.00 ATOM 631 2HG2 THR 157 2.199-4.071-5.814 1.00 0.00 ATOM 632 3HG2 THR 157 0.706-4.126-6.751 1.00 0.00 ATOM 633 C THR 157 2.646-7.047-4.684 1.00 0.00 ATOM 634 O THR 157 3.456-7.197-5.600 1.00 0.00 ATOM 635 N CYS 158 3.020-6.980-3.415 1.00 0.00 ATOM 636 H CYS 158 2.336-6.853-2.717 1.00 0.00 ATOM 637 CA CYS 158 4.424-7.087-3.037 1.00 0.00 ATOM 638 HA CYS 158 5.010-6.631-3.821 1.00 0. 00 ATOM 639 CB CYS 158 4.671-6.327-1.735 1.00 0.00 ATOM 640 1HB CYS 158 5.568-6.693-1.272 1.00 0.00 ATOM 641 2HB CYS 158 3.840-6.502-1.070 1.00 0.00 ATOM 642 QB CYS 158 4.704-6.597-1.171 1.00 0.00 ATOM 643 SG CYS 158 4.838-4.517-1.961 1.00 0.00 ATOM 644 C CYS 158 4.854-8.551-2.908 1.00 0.00 ATOM 645 O CYS 158 5.932-8.925-3.376 1.00 0.00 ATOM 646 N SER 159 4.018-9.365-2.268 1.00 0.00 ATOM 647 H SER 159 3.182-8.999-1.908 1.00 0.00 ATOM 648 CA SER 159 4.305-10.785-2.062 1.00 0. 00 ATOM 649 HA SER 159 5.304-10.855-1.657 1.00 0.00 ATOM 650 CB SER 159 3.327-11.380-1.050 1.00 0.00 ATOM 651 1HB SER 159 3.370-12.459-1.105 1.00 0.00 ATOM 652 2HB SER 159 2.325-11.047-1.282 1.00 0.00 ATOM 653 QB SER 159 2.848-11.753-1.193 1.00 0.00 ATOM 654 OG SER 159 3.654-10.972 0.272 1.00 0.00 ATOM 655 HG SER 159 4.610-11.007 0.386 1.00 0.00 ATOM 656 C SER 159 4.262-11.588-3.365 1.00 0.00 ATOM 657 O SER 159 4.904-12.631-3.460 1.00 0.00 ATOM 658 N GLU 160 3.520-11.102-4.365 1.00 0.00 ATOM 659 H GLU 160 3.029-10.261-4.238 1.00 0.00 ATOM 660 CA GLU 160 3.435-11.788-5.656 1.00 0.00 ATOM 661 HA GLU 160 3.139-12.811-5.476 1.00 0.00 ATOM 662 CB GLU 160 2.410-11.108-6.571 1.00 0. 00 ATOM 663 1HB GLU 160 2.911-10.347-7.152 1.00 0.00 ATOM 664 2HB GLU 160 1.652-10.639-5.961 1.00 0. 00 ATOM 665 QB GLU 160 2.282-10.493-6.556 1.00 0.00 ATOM 666 CG GLU 160 1.719-12.059-7.535 1.00 0.00 ATOM 667 1HG GLU 160 1.017-12.665-6.983 1.00 0.00 ATOM 668 2HG GLU 160 2.463-12.695-7.990 1.00 0.00 ATOM 669 QG GLU 160 1.740-12.680-7.486 1.00 0.00 ATOM 670 CD GLU 160 0.972-11.330-8.632 1.00 0.00 ATOM 671 OE1 GLU 160-0.071-11.845-9.082 1.00 0.00 ATOM 672 OE2 GLU 160 1.432-10.243-9.040 1.00 0.00 ATOM 673 C GLU 160 4.811-11.773-6.304 1.00 0.00 ATOM 674 O GLU 160 5.195-12.684-7.039 1.00 0.00 ATOM 675 N LYS+ 161 5.562-10.734-5.976 1.00 0.00 ATOM 676 H LYS+ 161 5.199-10.068-5.359 1.00 0.00 ATOM 677 CA LYS+ 161 6.914-10.575-6.457 1.00 0.00 ATOM 678 HA LYS+ 161 7.015-11.143-7.371 1.00 0.00 ATOM 679 CB LYS+ 161 7.223-9.098-6.728 1.00 0. 00 ATOM 680 1HB LYS+ 161 7.629-8.659-5.829 1.00 0.00

ATOM 681 2HB LYS+ 161 6.303-8.592-6.978 1.00 0. 00 ATOM 682 QB LYS+ 161 6.966-8.625-6.403 1.00 0.00 ATOM 683 CG LYS+ 161 8.218-8.881-7.860 1.00 0.00 ATOM 684 1HG LYS+ 161 7.677-8.569-8.744 1.00 0.00 ATOM 685 2HG LYS+ 161 8.724-9.812-8.058 1.00 0.00 ATOM 686 QG LYS+ 161 8.201-9.190-8.401 1.00 0.00 ATOM 687 CD LYS+ 161 9.251-7.819-7.509 1.00 0.00 ATOM 688 1HD LYS+ 161 9.110-7.522-6.479 1.00 0.00 ATOM 689 2HD LYS+ 161 9.102-6.963-8.152 1.00 0.00 ATOM 690 QD LYS+ 161 9.106-7.242-7.315 1.00 0.00 ATOM 691 CE LYS+ 161 10.683-8.321-7.688 1.00 0.00 ATOM 692 1HE LYS+ 161 11.186-8.275-6.731 1.00 0.00 ATOM 693 2HE LYS+ 161 11.192-7.672-8.387 1.00 0.00 ATOM 694 QE LYS+ 161 11.189-7.973-7.559 1.00 0.00 ATOM 695 NZ LYS+ 161 10.742-9.721-8.200 1.00 0.00 ATOM 696 1HZ LYS+ 161 10.797-10.398-7.397 1.00 0.00 ATOM 697 2HZ LYS+ 161 11.585-9.849-8.796 1.00 0.00 ATOM 698 3HZ LYS+ 161 9.898-9.938-8.764 1.00 0.00 ATOM 699 QZ LYS+ 161 10.760-10.061-8.319 1.00 0.00 ATOM 700 C LYS+ 161 7.862-11.137-5.408 1.00 0.00 ATOM 701 O LYS+ 161 7.611-12.190-4.833 1.00 0.00 ATOM 702 N SER 162 8.944-10.433-5.150 1.00 0.00 ATOM 703 H SER 162 9.097-9.597-5.623 1.00 0.00 ATOM 704 CA SER 162 9.900-10.877-4.159 1.00 0.00 ATOM 705 HA SER 162 9.545-11.814-3.759 1.00 0.00 ATOM 706 CB SER 162 11.270-11.103-4.803 1.00 0.00 ATOM 707 1HB SER 162 11.779-11.904-4.283 1.00 0.00 ATOM 708 2HB SER 162 11.855-10.198-4.725 1.00 0.00 ATOM 709 QB SER 162 11.817-11.051-4.504 1.00 0.00 ATOM 710 OG SER 162 11.139-11.455-6.178 1.00 0.00 ATOM 711 HG SER 162 11.146-12.419-6.255 1.00 0.00 ATOM 712 C SER 162 10.013-9.872-3.019 1.00 0.00 ATOM 713 O SER 162 11.112-9.463-2.662 1.00 0.00 ATOM 714 N THR 163 8.879-9.462-2.447 1.00 0.00 ATOM 715 H THR 163 8.013-9.807-2.768 1.00 0.00 ATOM 716 CA THR 163 8.906-8.514-1.338 1.00 0.00 ATOM 717 HA THR 163 9.853-8.639-0.828 1.00 0.00 ATOM 718 CB THR 163 8.802-7.066-1.822 1.00 0.00 ATOM 719 HB THR 163 8.706-6.431-0.945 1.00 0.00 ATOM 720 QG2 THR 163 10.290-6.468-2.793 1.00 0.00 ATOM 721 OG1 THR 163 7.663-6.883-2.643 1.00 0.00 ATOM 722 1HG THR 163 7.306-7.747-2.896 1.00 0.00 ATOM 723 CG2 THR 163 10.003-6.582-2.607 1.00 0.00 ATOM 724 1HG2 THR 163 9.683-6.228-3.575 1.00 0.00 ATOM 725 2HG2 THR 163 10.701-7.399-2.734 1.00 0.00 ATOM 726 3HG2 THR 163 10.486-5.779-2.070 1.00 0.00 ATOM 727 C THR 163 7.786-8.797-0.339 1.00 0.00 ATOM 728 O THR 163 6.777-9.417-0.667 1.00 0.00 ATOM 729 N ASN 164 7.975-8.332 0.884 1.00 0.00 ATOM 730 H ASN 164 8.810-7.846 1.082 1.00 0.00 ATOM 731 CA ASN 164 6.987-8.524 1.951 1.00 0.00 ATOM 732 HA ASN 164 6.119-9.008 1.517 1.00 0.00 ATOM 733 CB ASN 164 7.564-9.414 3.062 1.00 0.00 ATOM 734 1HB ASN 164 7.361-10.449 2.827 1.00 0.00 ATOM 735 2HB ASN 164 7.091-9.163 4.000 1.00 0.00 ATOM 736 QB ASN 164 7.226-9.806 3.414 1.00 0.00 ATOM 737 CG ASN 164 9.065-9.244 3.222 1.00 0.00 ATOM 738 OD1 ASN 164 9.784-10.204 3.463 1.00 0.00 ATOM 739 ND2 ASN 164 9.540-8.010 3.108 1.00 0.00 ATOM 740 1HD2 ASN 164 8.900-7.285 2.949 1.00 0.00 ATOM 741 2HD2 ASN 164 10.506-7.881 3.130 1.00 0.00 ATOM 742 QD2 ASN 164 9.703-7.583 3.040 1.00 0.00 ATOM 743 C ASN 164 6.565-7.184 2.550 1.00 0.00 ATOM 744 O ASN 164 7.410-6.337 2.836 1.00 0.00 ATOM 745 N LEU 165 5.264-6.996 2.741 1.00 0.00 ATOM 746 H LEU 165 4.642-7.709 2.497 1.00 0.00 ATOM 747 CA LEU 165 4.737-5.754 3.311 1.00 0. 00 ATOM 748 HA LEU 165 5.157-4.919 2.765 1.00 0. 00 ATOM 749 CB LEU 165 3.215-5.707 3.197 1.00 0.00 ATOM 750 1HB LEU 165 2.804-5.568 4.186 1.00 0.00 ATOM 751 2HB LEU 165 2.869-6.654 2.809 1.00 0.00 ATOM 752 QB LEU 165 2.837-6.111 3.498 1.00 0.00

ATOM 753 CG LEU 165 2.677-4.599 2.312 1.00 0.00 ATOM 754 HG LEU 165 3.164-3.669 2.569 1.00 0.00 ATOM 755 QD1 LEU 165 3.050-4.974 0.517 1.00 0.00 ATOM 756 QD2 LEU 165 0.831-4.387 2.579 1.00 0.00 ATOM 757 CD1 LEU 165 2.979-4.902 0.863 1.00 0.00 ATOM 758 1HD1 LEU 165 3.321-5.922 0.771 1.00 0.00 ATOM 759 2HD1 LEU 165 3.746-4.231 0.506 1.00 0.00 ATOM 760 3HD1 LEU 165 2.083-4.769 0.273 1.00 0.00 ATOM 761 CD2 LEU 165 1.185-4.428 2.529 1.00 0.00 ATOM 762 1HD2 LEU 165 0.849-3.535 2.022 1.00 0.00 ATOM 763 2HD2 LEU 165 0.981-4.341 3.586 1.00 0.00 ATOM 764 3HD2 LEU 165 0.662-5.285 2.130 1.00 0.00 ATOM 765 QQD LEU 165 1.941-4.680 1.548 1.00 0.00 ATOM 766 C LEU 165 5.117-5.610 4.770 1.00 0.00 ATOM 767 O LEU 165 4.804-6.469 5.591 1.00 0.00 ATOM 768 N HIS+ 166 5.772-4.509 5.080 1.00 0.00 ATOM 769 H HIS+ 166 5.980-3.858 4.376 1.00 0.00 ATOM 770 CA HIS+ 166 6.180-4.226 6.440 1.00 0.00 ATOM 771 HA HIS+ 166 5.934-5.084 7.048 1.00 0.00 ATOM 772 CB HIS+ 166 7.693-3.983 6.497 1.00 0.00 ATOM 773 1HB HIS+ 166 7.931-3.112 5.902 1.00 0.00 ATOM 774 2HB HIS+ 166 8.204-4.840 6.088 1.00 0.00 ATOM 775 QB HIS+ 166 8.068-3.976 5.995 1.00 0.00 ATOM 776 CG HIS+ 166 8.218-3.751 7.878 1.00 0.00 ATOM 777 ND1 HIS+ 166 8.307-4.739 8.835 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.675-2.623 8.461 1.00 0.00 ATOM 779 1HD HIS+ 166 8.045-5.677 8.717 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.797-4.223 9.950 1.00 0.00 ATOM 781 NE2 HIS+ 166 9.029-2.936 9.747 1.00 0.00 ATOM 782 2HD HIS+ 166 8.732-1.642 7.999 1.00 0.00 ATOM 783 1HE HIS+ 166 8.977-4.760 10.869 1.00 0.00 ATOM 784 2HE HIS+ 166 9.190-2.278 10.456 1.00 0.00 ATOM 785 C HIS+ 166 5.417-3.011 6.964 1.00 0.00 ATOM 786 O HIS+ 166 4.808-3.064 8.033 1.00 0.00 ATOM 787 N ASP 167 5.446-1.921 6.197 1.00 0.00 ATOM 788 H ASP 167 5.943-1.947 5.351 1.00 0.00 ATOM 789 CA ASP 167 4.754-0.690 6.587 1.00 0.00 ATOM 790 HA ASP 167 4.276-0.873 7.538 1.00 0.00 ATOM 791 CB ASP 167 5.738 0.477 6.745 1.00 0.00 ATOM 792 1HB ASP 167 5.337 1.178 7.462 1.00 0.00 ATOM 793 2HB ASP 167 5.848 0.974 5.794 1.00 0.00 ATOM 794 QB ASP 167 5.593 1.076 6.628 1.00 0.00 ATOM 795 CG ASP 167 7.113 0.050 7.217 1.00 0.00 ATOM 796 OD1 ASP 167 7.370 0.120 8.436 1.00 0.00 ATOM 797 OD2 ASP 167 7.938-0.351 6.366 1.00 0.00 ATOM 798 C ASP 167 3.685-0.310 5.565 1.00 0.00 ATOM 799 O ASP 167 3.952 0.410 4.606 1.00 0.00 ATOM 800 N TYR 168 2.477-0.804 5.773 1.00 0.00 ATOM 801 H TYR 168 2.330-1.374 6.557 1.00 0.00 ATOM 802 CA TYR 168 1.350-0.523 4.882 1.00 0.00 ATOM 803 HA TYR 168 1.741-0.298 3.892 1.00 0.00 ATOM 804 CB TYR 168 0.441-1.752 4.797 1.00 0.00 ATOM 805 1HB TYR 168 0.780-2.391 3.995 1.00 0.00 ATOM 806 2HB TYR 168-0.570-1.431 4.596 1.00 0.00 ATOM 807 QB TYR 168 0.105-1.911 4.296 1.00 0.00 ATOM 808 QD TYR 168 0.429-2.659 6.221 1.00 0.00 ATOM 809 QE TYR 168 0.425-3.959 8.305 1.00 0.00 ATOM 810 QR TYR 168 0.427-3.309 7.263 1.00 0.00 ATOM 811 CG TYR 168 0.428-2.567 6.073 1.00 0.00 ATOM 812 CD1 TYR 168 1.254-3.675 6.225 1.00 0.00 ATOM 813 1HD TYR 168 1.904-3.961 5.412 1.00 0. 00 ATOM 814 CE1 TYR 168 1.255-4.407 7.394 1.00 0.00 ATOM 815 1HE TYR 168 1.905-5.264 7.494 1.00 0.00 ATOM 816 CZ TYR 168 0.424-4.038 8.430 1.00 0.00 ATOM 817 CE2 TYR 168-0.405-2.944 8.303 1.00 0.00 ATOM 818 2HE TYR 168-1.055-2.654 9.115 1. 00 0. 00 ATOM 819 CD2 TYR 168-0.399-2.216 7.131 1.00 0.00 ATOM 820 2HD TYR 168-1.046-1.358 7.029 1.00 0.00 ATOM 821 OH TYR 168 0.420-4.766 9.595 1. 00 0. 00 ATOM 822 HH TYR 168 1.216-4.570 10.098 1.00 0.00 ATOM 823 C TYR 168 0.543 0.676 5.374 1.00 0.00 ATOM 824 O TYR 168 0.431 0.911 6.577 1.00 0.00

ATOM 825 N GLY 169-0.038 1.410 4.441 1.00 0.00 ATOM 826 H GLY 169 0.070 1.164 3.496 1.00 0.00 ATOM 827 CA GLY 169-0.847 2.559 4.781 1.00 0.00 ATOM 828 1HA GLY 169-0.238 3.451 4.730 1.00 0.00 ATOM 829 2HA GLY 169-1.226 2.442 5.786 1.00 0.00 ATOM 830 QA GLY 169-0.732 2.947 5.258 1.00 0.00 ATOM 831 C GLY 169-1.999 2.692 3.819 1.00 0.00 ATOM 832 O GLY 169-1. 947 2.146 2.718 1.00 0.00 ATOM 833 N MET 170-3.042 3.395 4.217 1.00 0.00 ATOM 834 H MET 170-3.035 3.806 5.108 1.00 0.00 ATOM 835 CA MET 170-4.202 3.573 3.356 1.00 0.00 ATOM 836 HA MET 170-3.889 3.380 2.334 1.00 0.00 ATOM 837 CB MET 170-5.314 2.592 3.738 1.00 0.00 ATOM 838 1HB MET 170-6.241 2.931 3.300 1.00 0.00 ATOM 839 2HB MET 170-5.418 2.582 4.813 1.00 0.00 ATOM 840 QB MET 170-5.829 2.757 4.057 1.00 0.00 ATOM 841 CG MET 170-5.058 1.168 3.270 1.00 0.00 ATOM 842 1HG MET 170-4.428 1.201 2.392 1.00 0.00 ATOM 843 2HG MET 170-6.003 0.712 3.015 1.00 0.00 ATOM 844 QG MET 170-5.215 0.957 2.704 1.00 0.00 ATOM 845 SD MET 170-4.250 0.155 4.524 1.00 0.00 ATOM 846 QE MET 170-3.004-1.111 3.315 1.00 0.00 ATOM 847 CE MET 170-3.213-0.900 3.517 1.00 0.00 ATOM 848 1HE MET 170-2.756-0.313 2.733 1.00 0.00 ATOM 849 2HE MET 170-3. 815-1. 682 3.079 1.00 0.00 ATOM 850 3HE MET 170-2.443-1.340 4.133 1.00 0.00 ATOM 851 C MET 170-4.709 5.003 3.454 1.00 0.00 ATOM 852 O MET 170-5.085 5.466 4.531 1.00 0.00 ATOM 853 N LEU 171-4. 700 5.702 2.331 1.00 0.00 ATOM 854 H LEU 171-4.377 5.280 1.508 1.00 0.00 ATOM 855 CA LEU 171-5.140 7.088 2.295 1.00 0.00 ATOM 856 HA LEU 171-5.401 7.375 3.302 1.00 0.00 ATOM 857 CB LEU 171-4.005 7.989 1.805 1.00 0.00 ATOM 858 1HB LEU 171-4.049 8.916 2.355 1.00 0.00 ATOM 859 2HB LEU 171-4.170 8.204 0.757 1.00 0.00 ATOM 860 QB LEU 171-4.109 8.560 1.556 1.00 0.00 ATOM 861 CG LEU 171-2.601 7.408 1.961 1.00 0.00 ATOM 862 HG LEU 171-2.643 6.545 2.609 1.00 0.00 ATOM 863 QD1 LEU 171-1.923 6.856 0.297 1.00 0.00 ATOM 864 QD2 LEU 171-1.455 8.671 2.748 1.00 0.00 ATOM 865 CD1 LEU 171-2.054 6.961 0.615 1.00 0.00 ATOM 866 1HD1 LEU 171-2.393 7.639-0.156 1.00 0.00 ATOM 867 2HD1 LEU 171-2.403 5.963 0.398 1.00 0.00 ATOM 868 3HD1 LEU 171-0.974 6.965 0. 648 1.00 0.00 ATOM 869 CD2 LEU 171-1.676 8.430 2.597 1.00 0.00 ATOM 870 1HD2 LEU 171-2.040 9.425 2.390 1.00 0.00 ATOM 871 2HD2 LEU 171-0.683 8.316 2.188 1.00 0.00 ATOM 872 3HD2 LEU 171-1.644 8.271 3.665 1. 00 0.00 ATOM 873 QQD LEU 171-1.689 7.764 1.522 1.00 0.00 ATOM 874 C LEU 171-6.361 7.270 1.402 1.00 0.00 ATOM 875 O LEU 171-7.072 6.309 1.105 1.00 0.00 ATOM 876 N LEU 172-6.582 8.519 0.984 1.00 0.00 ATOM 877 H LEU 172-5.959 9.220 1.268 1.00 0.00 ATOM 878 CA LEU 172-7.706 8.896 0.120 1.00 0.00 ATOM 879 HA LEU 172-7.794 9.971 0.158 1.00 0.00 ATOM 880 CB LEU 172-7.432 8.485-1.330 1.00 0.00 ATOM 881 1HB LEU 172-8.248 7.859-1.660 1.00 0.00 ATOM 882 2HB LEU 172-6.523 7.902-1.352 1.00 0.00 ATOM 883 QB LEU 172-7.385 7.881-1.506 1.00 0.00 ATOM 884 CG LEU 172-7.286 9.643-2.321 1.00 0.00 ATOM 885 HG LEU 172-6.373 10.181-2. 103 1.00 0.00 ATOM 886 QD1 LEU 172-7.167 8. 992-4. 077 1.00 0.00 ATOM 887 QD2 LEU 172-8.725 10.845-2.165 1.00 0.00 ATOM 888 CD1 LEU 172-7.191 9.116-3.741 1.00 0.00 ATOM 889 1HD1 LEU 172-7.807 9.720-4.390 1.00 0.00 ATOM 890 2HD1 LEU 172-7.532 8.092-3.769 1.00 0.00 ATOM 891 3HD1 LEU 172-6. 164 9.163-4.073 1.00 0.00 ATOM 892 CD2 LEU 172-8.450 10.614-2.195 1.00 0.00 ATOM 893 1HD2 LEU 172-8.788 10.899-3.180 1.00 0.00 ATOM 894 2HD2 LEU 172-8.128 11.494-1. 657 1.00 0.00 ATOM 895 3HD2 LEU 172-9.259 10.140-1.659 1.00 0.00 ATOM 896 QQD LEU 172-7.946 9.918-3.121 1.00 0.00

ATOM 897 C LEU 172-9.032 8.289 0.587 1.00 0.00 ATOM 898 O LEU 172-9.649 7.514-0.139 1.00 0.00 ATOM 899 N PRO 173-9.502 8.636 1.798 1.00 0.00 ATOM 900 CD PRO 173-8.866 9.562 2.746 1.00 0.00 ATOM 901 CA PRO 173-10.766 8.111 2.322 1.00 0.00 ATOM 902 HA PRO 173-10.774 7.030 2.325 1.00 0.00 ATOM 903 CB PRO 173-10. 819 8.633 3. 766 1. 00 0. 00 ATOM 904 1HB PRO 173-11.099 7.828 4.430 1.00 0.00 ATOM 905 2HB PRO 173-11. 548 9.428 3.832 1.00 0.00 ATOM 906 QB PRO 173-11. 323 8.628 4.131 1.00 0.00 ATOM 907 CG PRO 173-9.442 9.130 4.063 1.00 0.00 ATOM 908 1HG PRO 173-8.849 8.335 4.491 1.00 0.00 ATOM 909 2HG PRO 173-9.494 9.968 4.744 1.00 0.00 ATOM 910 QG PRO 173-9.171 9.152 4.618 1.00 0.00 ATOM 911 lHD PRO 173-7.793 9.442 2.743 1.00 0.00 ATOM 912 2HD PRO 173-9.137 10.586 2.531 1.00 0.00 ATOM 913 QD PRO 173-8.465 10. 014 2.637 1.00 0.00 ATOM 914 C PRO 173-11.963 8.623 1.528 1.00 0.00 ATOM 915 O PRO 173-12.208 9.827 1.469 1.00 0.00 ATOM 916 N CYS 174-12.703 7.711 0.916 1.00 0.00 ATOM 917 H CYS 174-12.462 6.764 0.993 1.00 0.00 ATOM 918 CA CYS 174-13.869 8.094 0.130 1.00 0.00 ATOM 919 HA CYS 174-13.872 9.173 0.065 1.00 0.00.

ATOM 920 CB CYS 174-13.788 7.516-1.284 1.00 0.00 ATOM 921 1HB CYS 174-12.757 7.279-1.506 1.00 0.00 ATOM 922 2HB CYS 174-14.138 8.259-1.984 1.00 0.00 ATOM 923 QB CYS 174-13.447 7.769-1.745 1.00 0.00 ATOM 924 SG CYS 174-14.773 6.006-1.551 1.00 0.00 ATOM 925 C CYS 174-15.151 7.655 0.824 1.00 0.00 ATOM 926 O CYS 174-16.250 8.047 0.432 1.00 0.00 ATOM 927 N GLY 175-15.000 6.857 1. 869 1.00 0.00 ATOM 928 H GLY 175-14.097 6.593 2.146 1.00 0.00 ATOM 929 CA GLY 175-16.144 6.393 2.622 1.00 0.00 ATOM 930 1HA GLY 175-16.335 5.360 2.379 1.00 0.00 ATOM 931 2HA GLY 175-17.007 6.988 2.356 1.00 0.00 ATOM 932 QA GLY 175-16.671 6.174 2.368 1.00 0.00 ATOM 933 C GLY 175-15.893 6.514 4.106 1.00 0.00 ATOM 934 O GLY 175-14.825 6.967 4.511 1.00 0.00 ATOM 935 N ILE 176-16.860 6.108 4.920 1.00 0.00 ATOM 936 H ILE 176-17.689 5.750 4.543 1.00 0.00 ATOM 937 CA ILE 176-16.705 6.178 6.368 1.00 0.00 ATOM 938 HA ILE 176-16.420 7.192 6.618 1.00 0.00 ATOM 939 CB ILE 176-18.033 5.850 7.102 1.00 0.00 ATOM 940 HB ILE 176-18. 685 6.705 7.001 1.00 0.00 ATOM 941 QG2 ILE 176-18.899 4.373 6.321 1.00 0.00 ATOM 942 CG2 ILE 176-18.733 4.656 6.469 1.00 0.00 ATOM 943 1HG2 ILE 176-19.458 4.257 7.164 1.00 0.00 ATOM 944 2HG2 ILE 176-18.005 3.894 6.235 1.00 0.00 ATOM 945 3HG2 ILE 176-19.235 4.968 5.565 1.00 0.00 ATOM 946 CG1 ILE 176-17.789 5.594 8.591 1.00 0.00 ATOM 947 1HG1 ILE 176-16.750 5.788 8.819 1.00 0.00 ATOM 948 2HG1 ILE 176-18.014 4.561 8.814 1.00 0.00 ATOM 949 QG1 ILE 176-17.382 5.175 8.817 1.00 0.00 ATOM 950 QD1 ILE 176-18.836 6.665 9.714 1.00 0.00 ATOM 951 CD1 ILE 176-18.635 6.459 9.498 1.00 0.00 ATOM 952 1HD1 ILE 176-19.472 6.854 8.941 1.00 0.00 ATOM 953 2HD1 ILE 176-18.037 7.275 9.877 1.00 0.00 ATOM 954 3HD1 ILE 176-18.999 5.866 10.324 1.00 0.00 ATOM 955 C ILE 176-15.587 5.234 6.826 1.00 0.00 ATOM 956 O ILE 176-14.762 5.593 7.664 1.00 0.00 ATOM 957 N ASP 177-15.559 4.038 6.242 1.00 0.00 ATOM 958 H ASP 177-16.234 3.826 5.569 1.00 0.00 ATOM 959 CA ASP 177-14.540 3.042 6. 557 1.00 0.00 ATOM 960 HA ASP 177-13.759 3.530 7.124 1.00 0.00 ATOM 961 CB ASP 177-15.135 1.907 7.399 1.00 0.00 ATOM 962 1HB ASP 177-15.734 1.272 6.763 1.00 0.00 ATOM 963 2HB ASP 177-15.759 2.327 8.172 1.00 0.00 ATOM 964 QB ASP 177-15.746 1.800 7.468 1.00 0.00 ATOM 965 CG ASP 177-14.069 1.052 8.059 1. 00 0. 00 ATOM 966 OD1 ASP 177-12.960 1.568 8.309 1.00 0.00 ATOM 967 OD2 ASP 177-14.342-0.138 8.318 1. oo 0. 00 ATOM 968 C ASP 177-13.942 2.480 5.269 1.00 0. 00

ATOM 969 O ASP 177-13.629 1.292 5.164 1.00 0.00 ATOM 970 N LYS+ 178-13.780 3.342 4.276 1.00 0.00 ATOM 971 H LYS+ 178-14.037 4.280 4.407 1.00 0.00 ATOM 972 CA LYS+ 178-13.210 2.926 3.005 1.00 0.00 ATOM 973 HA LYS+ 178-12.687 1.995 3.178 1.00 0.00 ATOM 974 CB LYS+ 178-14.291 2.694 1.948 1.00 0.00 ATOM 975 1HB LYS+ 178-13.855 2.838 0.970 1.00 0.00 ATOM 976 2HB LYS+ 178-15.071 3.415 2.091 1.00 0.00 ATOM 977 QB LYS+ 178-14.463 3.127 1.531 1.00 0.00 ATOM 978 CG LYS+ 178-14.898 1.293 2.000 1.00 0.00 ATOM 979 1HG LYS+ 178-14.937 0.971 3.032 1.00 0.00 ATOM 980 2HG LYS+ 178-14.267 0.621 1.437 1.00 0.00 ATOM 981 QG LYS+ 178-14.602 0.796 2.235 1.00 0.00 ATOM 982 CD LYS+ 178-16.303 1.251 1.414 1.00 0.00 ATOM 983 1HD LYS+ 178-16.449 2.124 0.794 1.00 0.00 ATOM 984 2HD LYS+ 178-17.019 1.261 2.223 1.00 0.00 ATOM 985 QD LYS+ 178-16.734 1.693 1.509 1.00 0.00 ATOM 986 CE LYS+ 178-16.533-0.001 0.567 1.00 0.00 ATOM 987 1HE LYS+ 178-16.134 0.175-0.424 1.00 0.00 ATOM 988 2HE LYS+ 178-17.595-0.181 0.495 1.00 0.00 ATOM 989 QE LYS+ 178-16.864-0.003 0.036 1.00 0.00 ATOM 990 NZ LYS+ 178-15.879-1.213 1.140 1.00 0.00 ATOM 991 1HZ LYS+ 178-15.141-0.945 1.820 1.00 0.00 ATOM 992 2HZ LYS+ 178-15.435-1.779 0.372 1.00 0.00 ATOM 993 3HZ LYS+ 178-16.579-1.810 1.620 1.00 0.00 ATOM 994 QZ LYS+ 178-15.718-1.511 1.271 1.00 0.00 ATOM 995 C LYS+ 178-12.198 3.943 2.524 1.00 0.00 ATOM 996 O LYS+ 178-12.313 5.139 2.795 1.00 0.00 ATOM 997 N PHE 179-11.198 3.448 1.827 1.00 0.00 ATOM 998 H PHE 179-11.174 2.483 1.657 1.00 0.00 ATOM 999 CA PHE 179-10.125 4.283 1.325 1.00 0.00 ATOM 1000 HA PHE 179-10.379 5.314 1.515 1.00 0.00 ATOM 1001 CB PHE 179-8.820 3.946 2.047 1.00 0.00 ATOM 1002 1HB PHE 179-8.071 4.649 1.741 1.00 0.00 ATOM 1003 2HB PHE 179-8. 503 2.958 1.757 1.00 0.00 ATOM 1004 QB PHE 179-8.287 3.804 1.749 1.00 0.00 ATOM 1005 QD PHE 179-8.928 3.991 3.714 1.00 0.00 ATOM 1006 QE PHE 179-9.099 4.066 6.167 1.00 0.00 ATOM 1007 QR PHE 179-9.048 4.044 5.431 1.00 0.00 ATOM 1008 CG PHE 179-8.917 3.987 3.547 1.00 0.00 ATOM 1009 CD1 PHE 179-9.361 2.883 4.260 1.00 0.00 ATOM 1010 1HD PHE 179-9.636 1.984 3.727 1.00 0.00 ATOM 1011 CE1 PHE 179-9.458 2.922 5.637 1.00 0.00 ATOM 1012 1HE PHE 179-9.809 2.056 6.180 1.00 0.00 ATOM 1013 CZ PHE 179-9.108 4.070 6.319 1.00 0.00 ATOM 1014 HZ PHE 179-9.185 4.105 7.397 1.00 0.00 ATOM 1015 CE2 PHE 179-8.663 5.176 5.622 1.00 0.00 ATOM 1016 2HE PHE 179-8.389 6.076 6.153 1.00 0. 00 ATOM 1017 CD2 PHE 179-8.570 5.132 4.244 1.00 0.00 ATOM 1018 2HD PHE 179-8.221 5.998 3.700 1.00 0.00 ATOM 1019 C PHE 179-9.925 4.080-0.159 1.00 0.00 ATOM 1020 O PHE 179-10.574 3.240-0.774 1.00 0.00 ATOM 1021 N ARG+ 180-9.001 4.838-0.720 1.00 0.00 ATOM 1022 H ARG+ 180-8.507 5.478-0.162 1.00 0.00 ATOM 1023 CA ARG+ 180-8.680 4.739-2.132 1.00 0.00 ATOM 1024 HA ARG+ 180-9.108 3.821-2.509 1.00 0.00 ATOM 1025 CB ARG+ 180-9.271 5.926-2.907 1.00 0.00 ATOM 1026 1HB ARG+ 180-9.016 5.817-3.951 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.828 6.837-2.533 1.00 0.00 ATOM 1028 QB ARG+ 180-8.922 6.327-3.242 1.00 0.00 ATOM 1029 CG ARG+ 180-10.785 6.053-2.794 1.00 0.00 ATOM 1030 1HG ARG+ 180-11.024 7.021-2.378 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.150 5.278-2.135 1.00 0.00 ATOM 1032 QG ARG+ 180-11.087 6.150-2.256 1.00 0.00 ATOM 1033 CD ARG+ 180-11.467 5.908-4.148 1.00 0.00 ATOM 1034 1HD ARG+ 180-12.259 5.178-4.058 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.739 5.557-4.866 1.00 0.00 ATOM 1036 QD ARG+ 180-11.499 5.368-4.462 1.00 0.00 ATOM 1037 NE ARG+ 180-12.035 7.171-4.625 1.00 0.00 ATOM 1038 HE ARG+ 180-11.772 7.991-4.152 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.865 7.266-5.669 1.00 0.00 ATOM 1040 NH1 ARG+ 180-13.232 6.173-6.330 1.00 0.00

ATOM 1041 1HH1 ARG+ 180-12.888 5.275-6.050 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.841 6.242-7.123 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.364 5.759-6.586 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.321 8.453-6.053 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-13.045 9.282-5.564 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.932 8.525-6.844 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13.488 8.904-6.204 1.00 0.00 ATOM 1048 C ARG+ 180-7.166 4.698-2.327 1.00 0.00 ATOM 1049 0 ARG+ 180-6.679 4.352-3.394 1.00 0.00 ATOM 1050 N GLY 181-6.420 5.058-1.292 1.00 0.00 ATOM 1051 H GLY 181-6.851 5.327-0.451 1.00 0.00 ATOM 1052 CA GLY 181-4.973 5.065-1.400 1.00 0.00 ATOM 1053 1HA GLY 181-4. 605 6.030-1.082 1.00 0. 00 ATOM 1054 2HA GLY 181-4.704 4.915-2.435 1. 00 0.00 ATOM 1055 QA GLY 181-4.654 5.473-1.758 1.00 0.00 ATOM 1056 C GLY 181-4.309 3.992-0.569 1.00 0.00 ATOM 1057 O GLY 181-4.860 3.544 0.435 1.00 0.00 ATOM 1058 N VAL 182-3.118 3.585-0.993 1.00 0.00 ATOM 1059 H VAL 182-2.740 3.993-1.798 1.00 0.00 ATOM 1060 CA VAL 182-2.344 2.561-0.300 1.00 0.00 ATOM 1061 HA VAL 182-2.642 2.550 0.742 1.00 0.00 ATOM 1062 CB VAL 182-2. 567 1.147-0.898 1.00 0.00 ATOM 1063 HB VAL 182-1.791 0.970-1.631 1.00 0. 00 ATOM 1064 QG1 VAL 182-2.408-0.164 0.435 1.00 0.00 ATOM 1065 QG2 VAL 182-4.233 0.998-1.763 1.00 0.00 ATOM 1066 CG1 VAL 182-2.439 0.087 0.180 1.00 0.00 ATOM 1067 1HG1 VAL 182-2.299 0.564 1.139 1.00 0.00 ATOM 1068 2HG1 VAL 182-1.590-0.545-0.036 1.00 0.00 ATOM 1069 3HG1 VAL 182-3.337-0.513 0.203 1.00 0.00 ATOM 1070 CG2 VAL 182-3.915 1.026-1.598 1.00 0.00 ATOM 1071 1HG2 VAL 182-4.650 1.612-1.066 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.222-0.009-1.613 1.00 0.00 ATOM 1073 3HG2 VAL 182-3. 829 1.391-2.611 1.00 0.00 ATOM 1074 QQG VAL 182-3.321 0.417-0.664 1.00 0.00 ATOM 1075 C VAL 182-0.853 2.890-0.387 1.00 0.00 ATOM 1076 O VAL 182-0.333 3.151-1.471 1.00 0.00 ATOM 1077 N GLU 183-0.176 2.872 0.753 1.00 0.00 ATOM 1078 H GLU 183-0.651 2.654 1.587 1.00 0.00 ATOM 1079 CA GLU 183 1.256 3.160 0.810 1.00 0.00 ATOM 1080 HA GLU 183 1.642 3.147-0.201 1.00 0.00 ATOM 1081 CB GLU 183 1.500 4.537 1.427 1.00 0.00 ATOM 1082 1HB GLU 183 1.567 5.268 0.634 1.00 0.00 ATOM 1083 2HB GLU 183 2.439 4.516 1.961 1.00 0. 00 ATOM 1084 QB GLU 183 2.003 4.892 1.298 1.00 0.00 ATOM 1085 CG GLU 183 0.420 4.987 2.395 1.00 0.00 ATOM 1086 1HG GLU 183 0.015 4.119 2.893 1.00 0. 00 ATOM 1087 2HG GLU 183-0. 362 5.483 1.841 1.00 0.00 ATOM 1088 QG GLU 183-0.173 4.801 2.367 1.00 0.00 ATOM 1089 CD GLU 183 0.950 5.940 3.441 1.00 0.00 ATOM 1090 OE1 GLU 183 1.995 6.578 3.185 1.00 0.00 ATOM 1091 OE2 GLU 183 0.321 6.051 4.511 1.00 0. 00 ATOM 1092 C GLU 183 1.961 2.087 1.626 1.00 0. 00 ATOM 1093 O GLU 183 1.965 2.126 2.848 1.00 0.00 ATOM 1094 N PHE 184 2.515 1.101 0.952 1.00 0.00 ATOM 1095 H PHE 184 2.454 1.096-0.021 1.00 0.00 ATOM 1096 CA PHE 184 3.162-0.008 1.634 1.00 0.00 ATOM 1097 HA PHE 184 3.059 0.164 2.693 1.00 0.00 ATOM 1098 CB PHE 184 2.453-1.321 1.283 1.00 0.00 ATOM 1099 1HB PHE 184 1.603-1.446 1.938 1.00 0.00 ATOM 1100 2HB PHE 184 3.138-2.143,1.443 1.00 0.00 ATOM 1101 QB PHE 184 2.371-1.794 1.691 1.00 0.00 ATOM 1102 QD PHE 184 1.899-1.416-0.309 1.00 0.00 ATOM 1103 QE PHE 184 1.077-1.597-2.617 1.00 0.00 ATOM 1104 QR PHE 184 1.322-1.544-1.925 1.00 0.00 ATOM 1105 CG PHE 184 1.957-1.407-0.145 1.00 0.00 ATOM 1106 CD1 PHE 184 2.544-2.283-1.041 1.00 0.00 ATOM 1107 1HD PHE 184 3.373-2.894-0.717 1.00 0.00 ATOM 1108 CE1 PHE 184 2.081-2.389-2.338 1.00 0.00 ATOM 1109 1HE PHE 184 2.551-3.078-3.024 1.00 0.00 ATOM 1110 CZ PHE 184 1.025-1.610-2.760 1.00 0.00 ATOM 1111 HZ PHE 184 0.659-1.697-3.772 1.00 0.00 ATOM 1112 CE2 PHE 184 0.431-0.729-1.883 1.00 0.00

ATOM 1113 2HE PHE 184-0.397-0.116-2.211 1.00 0.00 ATOM 1114 CD2 PHE 184 0.892-0.632-0.585 1.00 0.00 ATOM 1115 2HD PHE 184 0.424 0.061 0.099 1.00 0.00 ATOM 1116 C PHE 184 4.642-0.123 1.307 1.00 0.00 ATOM 1117 O PHE 184 5.046-0.039 0.151 1.00 0.00 ATOM 1118 N VAL 185 5.442-0.343 2.340 1.00 0.00 ATOM 1119 H VAL 185 5.051-0.416 3.239 1.00 0.00 ATOM 1120 CA VAL 185 6.877-0.498 2.184 1.00 0.00 ATOM 1121 HA VAL 185 7.152-0.159 1.194 1.00 0.00 ATOM 1122 CB VAL 185 7.654 0.334 3.233 1.00 0.00 ATOM 1123 HB VAL 185 7.870-0.304 4.082 1.00 0.00 ATOM 1124 QG1 VAL 185 9.281 0.946 2.532 1.00 0.00 ATOM 1125 QG2 VAL 185 6.633 1.789 3.845 1.00 0.00 ATOM 1126 CG1 VAL 185 8.970 0.827 2.665 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.169 0.329 1.729 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.763 0.615 3.366 1.00 0.00 ATOM 1129 3HG1 VAL 185 8.911 1.893 2.501 1.00 0.00 ATOM 1130 CG2 VAL 185 6.829 1.510 3.726 1.00 0.00 ATOM 1131 1HG2 VAL 185 6.982 2.358 3.076 1.00 0.00 ATOM 1132 2HG2 VAL 185 7.135 1.767 4.731 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.782 1.242 3.729 1.00 0.00 ATOM 1134 QQG VAL 185 7.957 1.368 3.189 1.00 0.00 ATOM 1135 C VAL 185 7.238-1.975 2.322 1.00 0.00 ATOM 1136 O VAL 185 7.259-2.523 3.421 1.00 0.00 ATOM 1137 N CYS 186 7.497-2.626 1.198 1.00 0. 00 ATOM 1138 H CYS 186 7.448-2.145 0.341 1.00 0.00 ATOM 1139 CA CYS 186 7.834-4.042 1.205 1.00 0.00 ATOM 1140 HA CYS 186 7.656-4.415 2.206 1.00 0.00 ATOM 1141 CB CYS 186 6.937-4.816 0.228 1.00 0.00 ATOM 1142 1HB CYS 186 5.953-4.913 0.663 1.00 0.00 ATOM 1143 2HB CYS 186 7.353-5.798 0.079 1.00 0.00 ATOM 1144 QB CYS 186 6.653-5.355 0.371 1.00 0.00 ATOM 1145 SG CYS 186 6.744-4.056-1.415 1.00 0.00 ATOM 1146 C CYS 186 9.306-4.253 0.864 1.00 0.00 ATOM 1147 O CYS 186 9.796-3.732-0.130 1.00 0.00 ATOM 1148 N CYS 187 10.013-5.020 1.686 1.00 0.00 ATOM 1149 H CYS 187 9.576-5.419 2.468 1.00 0.00 ATOM 1150 CA CYS 187 11.436-5.275 1.446 1.00 0.00 ATOM 1151 HA CYS 187 11.831-4.438 0.894 1.00 0.00 ATOM 1152 CB CYS 187 12.203-5.407 2.766 1.00 0.00 ATOM 1153 1HB CYS 187 13.015-6.110 2.631 1.00 0.00 ATOM 1154 2HB CYS 187 11.536-5.781 3.528 1.00 0.00 ATOM 1155 QB CYS 187 12.276-5.945 3.080 1.00 0.00 ATOM 1156 SG CYS 187 12.917-3.846 3.372 1.00 0.00 ATOM 1157 C CYS 187 11.630-6.536 0.626 1.00 0.00 ATOM 1158 O CYS 187 10.785-7.426 0.651 1.00 0. 00 ATOM 1159 N PRO 188 12.744-6.618-0.123 1.00 0.00 ATOM 1160 CD PRO 188 13.793-5.582-0.213 1.00 0. 00 ATOM 1161 CA PRO 188 13.042-7.779-0.966 1.00 0.00 ATOM 1162 HA PRO 188 12.237-7.975-1.661 1.00 0.00 ATOM 1163 CB PRO 188 14.295-7.360-1.742 1.00 0.00 ATOM 1164 1HB PRO 188 14.013-7.008-2.722 1.00 0.00 ATOM 1165 2HB PRO 188 14.958-8.210-1.837 1.00 0.00 ATOM 1166 QB PRO 188 14.486-7.609-2.279 1.00 0.00 ATOM 1167 CG PRO 188 14.918-6.275-0.931 1.00 0.00 ATOM 1168 1HG PRO 188 15.431-5.581-1.580 1.00 0.00 ATOM 1169 2HG PRO 188 15.609-6.702-0.218 1.00 0.00 ATOM 1170 QG PRO 188 15.520-6.141-0.899 1.00 0.00 ATOM 1171 1HD PRO 188 13.449-4.729-0.780 1.00 0.00 ATOM 1172 2HD PRO 188 14.114-5.273 0.772 1.00 0.00 ATOM 1173 QD PRO 188 13.782-5.001-0.004 1.00 0.00 ATOM 1174 C PRO 188 13.312-9.044-0.154 1.00 0.00 ATOM 1175 O PRO 188 14.154-9.049 0.748 1.00 0.00 ATOM 1176 N LEU 189 12.593-10.105-0.492 1.00 0.00 ATOM 1177 H LEU 189 11.945-10.024-1.225 1.00 0.00 ATOM 1178 CA LEU 189 12.735-11.391 0.170 1.00 0.00 ATOM 1179 HA LEU 189 13.637-11.366 0.763 1.00 0. 00 ATOM 1180 CB LEU 189 11.536-11.664 1.082 1.00 0.00 ATOM 1181 1HB LEU 189 10. 679-11. 867 0.459 1.00 0.00 ATOM 1182 2HB LEU 189 11.339-10.773 1.660 1.00 0.00 ATOM 1183 QB LEU 189 11.009-11.320 1.060 1.00 0.00 ATOM 1184 CG LEU 189 11.712-12.837 2.049 1.00 0.00

ATOM 1185 HG LEU 189 12.337-13. 585 1.581 1.00 0.00 ATOM 1186 QD1 LEU 189 12.564-12.271 3.626 1.00 0.00 ATOM 1187 QD2 LEU 189 10.052-13.623 2.440 1.00 0.00 ATOM 1188 CD1 LEU 189 12.400-12. 380 3.325 1.00 0.00 ATOM 1189 1HD1 LEU 189 13.365-11.960 3.081 1.00 0.00 ATOM 1190 2HD1 LEU 189 12.531-13.224 3.985 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.794-11.631 3.812 1.00 0.00 ATOM 1192 CD2 LEU 189 10.369-13.473 2.365 1.00 0.00 ATOM 1193 1HD2 LEU 189 10.090-14. 140 1.563 1.00 0.00 ATOM 1194 2HD2 LEU 189 9.621-12. 701 2.470 1.00 0.00 ATOM 1195 3HD2 LEU 189 10.443-14. 030 3.287 1.00 0.00 ATOM 1196 QQD LEU 189 11.308-12.947 3.033 1.00 0.00 ATOM 1197 C LEU 189 12. 855-12.497-0.874 1.00 0.00 ATOM 1198 OT1 LEU 189 13.403-13.569-0.546 1.00 0.00 ATOM 1199 OT2 LEU 189 12.396-12.278-2.018 1.00 0.00 TER ENDMDL MODEL 7 ATOM 1 N SER 124 16.651 11. 785 4.595 1.00 0.00 ATOM 2 CA SER 124 15.856 10. 532 4.581 1.00 0.00 ATOM 3 HA SER 124 16.294 9.842 3.875 1.00 0.00 ATOM 4 CB SER 124 15.899 9.931 5.984 1.00 0.00 ATOM 5 1HB SER 124 16.119 8.876 5.916 1.00 0.00 ATOM 6 2HB SER 124 14.938 10.070 6.462 1.00 0.00 ATOM 7 QB SER 124 15.529 9.473 6.189 1.00 0.00 ATOM 8 OG SER 124 16.902 10. 562 6.770 1.00 0.00 ATOM 9 HG SER 124 16.803 10.297 7.693 1.00 0.00 ATOM 10 C SER 124 14.429 10.838 4.170 1.00 0.00 ATOM 11 O SER 124 13.479 10.555 4.900 1.00 0.00 ATOM 12 1HT SER 124 17.393 11.751 3.870 1.00 0.00 ATOM 13 2HT SER 124 17.095 11.910 5.528 1.00 0.00 ATOM 14 3HT SER 124 16.029 12.606 4.405 1.00 0.00 ATOM 15 N ASP 125 14.302 11.466 3.014 1.00 0.00 ATOM 16 H ASP 125 15.107 11.692 2.501 1.00 0.00 ATOM 17 CA ASP 125 13.015 11.885 2.501 1.00 0.00 ATOM 18 HA ASP 125 12.260 11. 603 3.218 1.00 0.00 ATOM 19 CB ASP 125 13.017 13.411 2.350 1.00 0.00 ATOM 20 1HB ASP 125 12.276 13.835 3.012 1.00 0.00 ATOM 21 2HB ASP 125 12.770 13.666 1.329 1.00 0.00 ATOM 22 QB ASP 125 12.523 13.751 2.171 1.00 0.00 ATOM 23 CG ASP 125 14.370 14.024 2.684 1.00 0.00 ATOM 24 OD1 ASP 125 14.783 13.968 3.868 1.00 0.00 ATOM 25 OD2 ASP 125 15.036 14.526 1.762 1.00 0.00 ATOM 26 C ASP 125 12.713 11.218 1.168 1.00 0.00 ATOM 27 O ASP 125 13.441 11. 398 0.194 1.00 0.00 ATOM 28 N ALA 126 11.636 10. 444 1.135 1.00 0.00 ATOM 29 H ALA 126 11.096 10.340 1.947 1.00 0.00 ATOM 30 CA ALA 126 11.229 9.745-0.076 1.00 0.00 ATOM 31 HA ALA 126 11.362 10.417-0.911 1.00 0.00 ATOM 32 QB ALA 126 12.306 8.227-0.362 1.00 0.00 ATOM 33 CB ALA 126 12.100 8.517-0.307 1.00 0.00 ATOM 34 1HB ALA 126 13.133 8.766-0.112 1.00 0.00 ATOM 35 2HB ALA 126 11.997 8.189-1.331 1.00 0.00 ATOM 36 3HB ALA 126 11.788 7.724 0.357 1.00 0.00 ATOM 37 C ALA 126 9.768 9.334 0.009 1.00 0.00 ATOM 38 O ALA 126 9.312 8.851 1.042 1.00 0.00 ATOM 39 N LEU 127 9.041 9.517-1.085 1.00 0.00 ATOM 40 H LEU 127 9.463 9.898-1.880 1.00 0.00 ATOM 41 CA LEU 127 7.632 9.151-1.137 1.00 0.00 ATOM 42 HA LEU 127 7.270 9.084-0.123 1. 00 0. 00 ATOM 43 CB LEU 127 6.830 10.217-1.891 1.00 0.00 ATOM 44 1HB LEU 127 6.902 10.009-2.949 1.00 0.00 ATOM 45 2HB LEU 127 7.281 11.180-1.700 1.00 0.00 ATOM 46 QB LEU 127 7.092 10. 595-2. 324 1.00 0.00 ATOM 47 CG LEU 127 5.347 10.299-1.522 1.00 0.00 ATOM 48 HG LEU 127 5.001 9.317-1.228 1.00 0.00 ATOM 49 QD1 LEU 127 5.084 11.464-0.071 1.00 0.00 ATOM 50 QD2 LEU 127 4.330 10.855-3.001 1.00 0.00 ATOM 51 CD1 LEU 127 5.136 11.241-0.349 1.00 0.00 ATOM 52 1HD1 LEU 127 4.797 12.200-0.714 1.00 0.00 ATOM 53 2HD1 LEU 127 6.065 11.366 0.186 1. 00 0.00 ATOM 54 3HD1 LEU 127 4.391 10.826 0.316 1.00 0.00

ATOM 55 CD2 LEU 127 4.525 10.748-2.718 1.00 0.00 ATOM 56 1HD2 LEU 127 4.474 11.827-2.736 1.00 0.00 ATOM 57 2HD2 LEU 127 3.527 10.342-2.641 1.00 0.00 ATOM 58 3HD2 LEU 127 4.988 10.394-3.627 1.00 0.00 ATOM 59 QQD LEU 127 4.707 11.159-1.536 1.00 0.00 ATOM 60 C LEU 127 7.466 7.795-1.814 1.00 0.00 ATOM 61 O LEU 127 6.353 7.360-2.108 1.00 0.00 ATOM 62 N LEU 128 8.587 7.133-2.061 1.00 0.00 ATOM 63 H LEU 128 9.443 7.529-1.803 1.00 0.00 ATOM 64 CA LEU 128 8.578 5.833-2.701 1.00 0.00 ATOM 65 HA LEU 128 7.625 5.369-2.503 1.00 0.00 ATOM 66 CB LEU 128 8.753 5.996-4.215 1.00 0.00 ATOM 67 1HB LEU 128 9.809 5.957-4.438 1.00 0.00 ATOM 68 2HB LEU 128 8.379 6.970-4.495 1.00 0.00 ATOM 69 QB LEU 128 9.094 6.464-4.466 1.00 0.00 ATOM 70 CG LEU 128 8.041 4.943-5.071 1.00 0.00 ATOM 71 HG LEU 128 8.035 4.000-4.544 1.00 0.00 ATOM 72 QD1 LEU 128 6.256 5.446-5.377 1.00 0.00 ATOM 73 QD2 LEU 128 8.942 4.702-6.704 1.00 0.00 ATOM 74 CD1 LEU 128 6.598 5.349-5.318 1.00 0.00 ATOM 75 1HD1 LEU 128 6.528 5.876-6.259 1.00 0.00 ATOM 76 2HD1 LEU 128 6.262 5.994-4.519 1.00 0.00 ATOM 77 3HD1 LEU 128 5.977 4.467-5.354 1.00 0.00 ATOM 78 CD2 LEU 128 8.770 4.747-6.391 1.00 0.00 ATOM 79 1HD2 LEU 128 8.240 4.022-6.990 1.00 0.00 ATOM 80 2HD2 LEU 128 9.773 4.396-6.202 1.00 0.00 ATOM 81 3HD2 LEU 128 8.812 5.688-6.921 1.00 0.00 ATOM 82 QQD LEU 128 7.599 5.074-6.041 1.00 0.00 ATOM 83 C LEU 128 9.683 4.959-2.118 1.00 0.00 ATOM 84 O LEU 128 10.047 5.118-0.955 1.00 0.00 ATOM 85 N VAL 129 10.191 4.039-2.931 1.00 0.00 ATOM 86 H VAL 129 9.835 3.978-3.840 1.00 0.00 ATOM 87 CA VAL 129 11.249 3.107-2.527 1.00 0.00 ATOM 88 HA VAL 129 10.820 2.396-1.840 1.00 0.00 ATOM 89 CB VAL 129 11.789 2.330-3.748 1.00 0.00 ATOM 90 HB VAL 129 12.501 2.963-4.260 1.00 0.00 ATOM 91 QG1 VAL 129 12.686 0.767-3.211 1.00 0.00 ATOM 92 QG2 VAL 129 10.403 1.918-4.951 1.00 0.00 ATOM 93 CG1 VAL 129 12.513 1.066-3.314 1.00 0.00 ATOM 94 1HG1 VAL 129 12.957 1.220-2.341 1.00 0.00 ATOM 95 2HG1 VAL 129 13.289 0.833-4.029 1.00 0.00 ATOM 96 3HG1 VAL 129 11.812 0.246-3.264 1.00 0.00 ATOM 97 CG2 VAL 129 10.667 1.996-4.720 1.00 0.00 ATOM 98 1HG2 VAL 129 9.723 2.001-4.196 1.00 0.00 ATOM 99 2HG2 VAL 129 10.841 1.019-5.146 1.00 0.00 ATOM 100 3HG2 VAL 129 10.644 2.734-5.510 1.00 0.00 ATOM 101 QQG VAL 129 11.544 1.342-4.081 1.00 0.00 ATOM 102 C VAL 129 12.425 3.810-1.842 1.00 0.00 ATOM 103 O VAL 129 13.181 4.534-2.487 1.00 0.00 ATOM 104 N PRO 130 12.586 3.597-0.520 1.00 0.00 ATOM 105 CD PRO 130 11.716 2.757 0.322 1.00 0.00 ATOM 106 CA PRO 130 13.672 4.197 0.251 1.00 0.00 ATOM 107 HA PRO 130 13.811 5.236-0.011 1.00 0.00 ATOM 108 CB PRO 130 13.175 4.091 1.692 1.00 0.00 ATOM 109 1HB PRO 130 12.618 4.979 1.949 1.00 0.00 ATOM 110 2HB PRO 130 14.018 3.981 2.358 1.00 0.00 ATOM 111 QB PRO 130 13.318 4.480 2.154 1.00 0.00 ATOM 112 CG PRO 130 12.304 2.880 1.705 1.00 0.00 ATOM 113 1HG PRO 130 11.518 3.004 2.436 1.00 0.00 ATOM 114 2HG PRO 130 12.896 2.008 1.937 1.00 0.00 ATOM 115 QG PRO 130 12.207 2.506 2.187 1.00 0.00 ATOM 116 1HD PRO 130 10.700 3.128 0.311 1.00 0.00 ATOM 117 2HD PRO 130 11.745 1.728-0.008 1.00 0.00 ATOM 118 QD PRO 130 11.223 2.428 0.152 1.00 0.00 ATOM 119 C PRO 130 14.999 3.451 0.075 1.00 0.00 ATOM 120 O PRO 130 15.178 2.692-0.877 1.00 0.00 ATOM 121 N ASP 131 15.925 3.689 0.998 1.00 0.00 ATOM 122 H ASP 131 15.725 4.311 1.721 1.00 0.00 ATOM 123 CA ASP 131 17.247 3. 082 0.966 1.00 0.00 ATOM 124 HA ASP 131 17.594 3.085-0.056 1.00 0.00 ATOM 125 CB ASP 131 18.188 3.941 1.804 1.00 0.00 ATOM 126 1HB ASP 131 18.855 3.299 2.342 1.00 0.00

ATOM 127 2HB ASP 131 17.608 4.516 2.508 1.00 0. 00 ATOM 128 QB ASP 131 18.232 3.908 2.425 1.00 0.00 ATOM 129 CG ASP 131 19.004 4.901 0.968 1.00 0.00 ATOM 130 OD1 ASP 131 18.873 6.126 1.183 1.00 0.00 ATOM 131 OD2 ASP 131 19.768 4.433 0.101 1.00 0.00 ATOM 132 C ASP 131 17.264 1.645 1.499 1.00 0.00 ATOM 133 0 ASP 131 18.324 1.022 1.579 1.00 0.00 ATOM 134 N LYS+ 132 16.111 1.115 1.893 1.00 0.00 ATOM 135 H LYS+ 132 15.291 1.644 1.831 1.00 0.00 ATOM 136 CA LYS+ 132 16.067-0.244 2.434 1.00 0.00 ATOM 137 HA LYS+ 132 17.031-0.694 2.246 1.00 0.00 ATOM 138 CB LYS+ 132 15.831-0.208 3.949 1.00 0.00 ATOM 139 1HB LYS+ 132 15.077-0.940 4.201 1.00 0.00 ATOM 140 2HB LYS+ 132 15.472 0.774 4.221 1.00 0.00 ATOM 141 QB LYS+ 132 15.275-0.083 4.211 1.00 0.00 ATOM 142 CG LYS+ 132 17. 079-0. 504 4.771 1.00 0.00 ATOM 143 1HG LYS+ 132 16.794-0.632 5.805 1.00 0.00 ATOM 144 2HG LYS+ 132 17.759 0.332 4.684 1.00 0.00 ATOM 145 QG LYS+ 132 17.277-0.150 5.245 1.00 0.00 ATOM 146 CD LYS+ 132 17.786-1.765 4.289 1.00 0.00 ATOM 147 1HD LYS+ 132 18.741-1.489 3.861 1.00 0.00 ATOM 148 2HD LYS+ 132 17.178-2.238 3.530 1.00 0.00 ATOM 149 QD LYS+ 132 17.960-1.863 3.696 1.00 0.00 ATOM 150 CE LYS+ 132 18.018-2.756 5.422 1.00 0.00 ATOM 151 1HE LYS+ 132 18.899-3.340 5.195 1.00 0.00 ATOM 152 2HE LYS+ 132 17.162-3.413 5.488 1.00 0.00 ATOM 153 QE LYS+ 132 18.031-3.376 5.342 1.00 0.00 ATOM 154 NZ LYS+ 132 18.209-2.075 6.735 1.00 0.00 ATOM 155 1HZ LYS+ 132 18.910-2.590 7.307 1.00 0.00 ATOM 156 2HZ LYS+ 132 17.310-2.043 7.258 1.00 0.00 ATOM 157 3HZ LYS+ 132 18.547-1.101 6. 587 1.00 0.00 ATOM 158 QZ LYS+ 132 18.256-1.911 7.051 1.00 0.00 ATOM 159 C LYS+ 132 14.997-1.104 1.765 1.00 0.00 ATOM 160 O LYS+ 132 15.305-2.025 1.013 1.00 0.00 ATOM 161 N CYS 133 13.741-0.820 2.069 1.00 0.00 ATOM 162 H CYS 133 13.553-0.091 2.691 1.00 0.00 ATOM 163 CA CYS 133 12.632-1.584 1.513 1.00 0.00 ATOM 164 HA CYS 133 13.017-2.541 1.191 1.00 0.00 ATOM 165 CB CYS 133 11.573-1.815 2.593 1.00 0.00 ATOM 166 1HB CYS 133 10.837-2.514 2.225 1.00 0.00 ATOM 167 2HB CYS 133 11.089-0.876 2.822 1.00 0.00 ATOM 168 QB CYS 133 10.963-1.695 2.524 1.00 0.00 ATOM 169 SG CYS 133 12.250-2.486 4.149 1.00 0.00 ATOM 170 C CYS 133 12.033-0.866 0.309 1.00 0.00 ATOM 171 0 CYS 133 12.637 0.051-0.232 1.00 0.00 ATOM 172 N LYS+ 134 10.851-1.289-0.111 1.00 0.00 ATOM 173 H LYS+ 134 10.414-2.033 0.355 1.00 0.00 ATOM 174 CA LYS+ 134 10.180-0.688-1.254 1.00 0.00 ATOM 175 HA LYS+ 134 10.832 0.066-1.668 1.00 0.00 ATOM 176 CB LYS+ 134 9.903-1.758-2.315 1.00 0.00 ATOM 177 1HB LYS+ 134 9.109-2.400-1.960 1.00 0.00 ATOM 178 2HB LYS+ 134 10.796-2.349-2.451 1.00 0.00 ATOM 179 QB LYS+ 134 9.953-2.374-2.205 1.00 0.00 ATOM 180 CG LYS+ 134 9.494-1.201-3.669 1.00 0.00 ATOM 181 1HG LYS+ 134 10.230-0.476-3.987 1.00 0.00 ATOM 182 2HG LYS+ 134 8.529-0.725-3.574 1.00 0.00 ATOM 183 QG LYS+ 134 9.380-0.600-3.780 1.00 0.00 ATOM 184 CD LYS+ 134 9.401-2.305-4.713 1.00 0.00 ATOM 185 1HD LYS+ 134 9.299-3.255-4.206 1.00 0.00 ATOM 186 2HD LYS+ 134 10.306-2.308-5.303 1.00 0.00 ATOM 187 QD LYS+ 134 9.803-2.781-4.754 1.00 0.00 ATOM 188 CE LYS+ 134 8.208-2.111-5.639 1.00 0.00 ATOM 189 1HE LYS+ 134 7.381-2.699-5.266 1.00 0.00 ATOM 190 2HE LYS+ 134 8.477-2.458-6.626 1.00 0.00 ATOM 191 QE LYS+ 134 7.929-2.578-5.946 1.00 0.00 ATOM 192 NZ LYS+ 134 7.789-0.682-5.725 1.00 0. 00 ATOM 193 1HZ LYS+ 134 6.917-0.532-5.171 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.604-0.421-6. 714 1.00 0.00 ATOM 195 3HZ LYS+ 134 8.536-0.065-5.349 1.00 0.00 ATOM 196 QZ LYS+ 134 7.686-0.339-5.745 1.00 0.00 ATOM 197 C LYS+ 134 8.876-0.039-0.813 1.00 0.00 ATOM 198 0 LYS+ 134 7.917-0.728-0.490 1.00 0.00

ATOM 199 N PHE 135 8.847 1. 283-0.801 1.00 0.00 ATOM 200 H PHE 135 9.643 1.783-1.071 1.00 0.00 ATOM 201 CA PHE 135 7.654 2.014-0.394 1.00 0.00 ATOM 202 HA PHE 135 7.076 1.374 0.258 1.00 0.00 ATOM 203 CB PHE 135 8.056 3.281 0.369 1.00 0.00 ATOM 204 1HB PHE 135 8.632 3.916-0.290 1.00 0.00 ATOM 205 2HB PHE 135 8.672 3.001 1.210 1.00 0.00 ATOM 206 QB PHE 135 8.652 3.459 0.460 1.00 0.00 ATOM 207 QD PHE 135 6.783 4.186 0.964 1.00 0.00 ATOM 208 QE PHE 135 4.929 5.532 1.855 1.00 0.00 ATOM 209 QR PHE 135 5.484 5.129 1.588 1.00 0.00 ATOM 210 CG PHE 135 6.909 4.094 0.903 1.00 0.00 ATOM 211 CD1 PHE 135 5.810 3.485 1.482 1.00 0.00 ATOM 212 1HD PHE 135 5.770 2.407 1.542 1.00 0.00 ATOM 213 CE1 PHE 135 4.768 4.239 1.984 1.00 0.00 ATOM 214 1HE PHE 135 3.915 3.750 2.435 1.00 0.00 ATOM 215 CZ PHE 135 4.814 5.616 1.910 1.00 0.00 ATOM 216 HZ PHE 135 3.998 6.207 2.303 1.00 0.00 ATOM 217 CE2 PHE 135 5.903 6.236 1.334 1.00 0.00 ATOM 218 2HE PHE 135 5.942 7.313 1.274 1.00 0.00 ATOM 219 CD2 PHE 135 6.944 5.477 0.836 1.00 0.00 ATOM 220 2HD PHE 135 7.796 5.965 0.385 1.00 0.00 ATOM 221 C PHE 135 6.815 2.360-1.617 1.00 0.00 ATOM 222 O PHE 135 7.335 2.834-2.628 1.00 0.00 ATOM 223 N LEU 136 5.523 2.091-1.529 1.00 0. 00 ATOM 224 H LEU 136 5.173 1.690-0.701 1.00 0.00 ATOM 225 CA LEU 136 4.610 2.347-2.626 1.00 0.00 ATOM 226 HA LEU 136 5.150 2.886-3.389 1.00 0.00 ATOM 227 CB LEU 136 4.094 1.030-3.216 1.00 0.00 ATOM 228 1HB LEU 136 3.300 1.262-3.912 1.00 0.00 ATOM 229 2HB LEU 136 3.678 0.441-2.410 1.00 0.00 ATOM 230 QB LEU 136 3.489 0.852-3.161 1.00 0.00 ATOM 231 CG LEU 136 5.136 0.180-3.944 1.00 0.00 ATOM 232 HG LEU 136 5.938 0.817-4.284 1.00 0.00 ATOM 233 QD1 LEU 136 5.859-1.109-2.781 1.00 0.00 ATOM 234 QD2 LEU 136 4.366-0.655-5.442 1.00 0.00 ATOM 235 CD1 LEU 136 5.721-0.862-3.006 1.00 0.00 ATOM 236 1HD1 LEU 136 5.010-1.078-2.221 1.00 0.00 ATOM 237 2HD1 LEU 136 6.633-0.483-2.567 1.00 0.00 ATOM 238 3HD1 LEU 136 5.933-1.767-3.555 1.00 0.00 ATOM 239 CD2 LEU 136 4.515-0.495-5.156 1.00 0.00 ATOM 240 1HD2 LEU 136 4.819-1.531-5.186 1.00 0.00 ATOM 241 2HD2 LEU 136 4.840 0.005-6.056 1.00 0.00 ATOM 242 3HD2 LEU 136 3.438-0.440-5.084 1.00 0.00 ATOM 243 QQD LEU. 136 5.112-0.882-4.111 1.00 0.00 ATOM 244 C LEU 136 3.431 3.190-2.167 1.00 0.00 ATOM 245 O LEU 136 2.380 2.657-1.819 1.00 0.00 ATOM 246 N HIS+ 137 3.599 4.502-2.189 1. 00 0. 00 ATOM 247 H HIS+ 137 4.453 4.874-2.492 1.00 0. 00 ATOM 248 CA HIS+ 137 2.527 5.404-1.802 1.00 0. 00 ATOM 249 HA HIS+ 137 1.853 4.859-1.150 1.00 0.00 ATOM 250 CB HIS+ 137 3.084 6.637-1.059 1.00 0.00 ATOM 251 1HB HIS+ 137 3.932 7.021-1.608 1.00 0.00 ATOM 252 2HB HIS+ 137 3.412 6.334-0.076 1.00 0.00 ATOM 253 QB HIS+ 137 3.672 6.678-0.842 1.00 0.00 ATOM 254 CG HIS+ 137 2.097 7.764-0.886 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.479 8.058 0.312 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.620 8.670-1.777 1.00 0.00 ATOM 257 1HD HIS+ 137 1.617 7.582 1.173 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.667 9.088 0.146 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.732 9.480-1.113 1.00 0.00 ATOM 260 2HD HIS+ 137 1.890 8.741-2.822 1.00 0.00 ATOM 261 1HE HIS+ 137 0.051 9.533 0.914 1.00 0.00 ATOM 262 2HE HIS+ 137 0.067 10.071-1.555 1.00 0.00 ATOM 263 C HIS+ 137 1.780 5.828-3.059 1.00 0.00 ATOM 264 O HIS+ 137 2.349 6. 489-3.932 1.00 0.00 ATOM 265 N GLN 138 0.521 5.438-3.166 1.00 0.00 ATOM 266 H GLN 138 0.119 4.899-2.447 1.00 0.00 ATOM 267 CA GLN 138-0.277 5.780-4.333 1. 00 0.00 ATOM 268 HA GLN 138 0.155 6.665-4.778 1.00 0.00 ATOM 269 CB GLN 138-0.246 4.643-5.357 1.00 0.00 ATOM 270 1HB GLN 138-1.176 4.645-5.906 1.00 0.00

ATOM 271 2HB GLN 138-0.154 3.706-4.830 1.00 0.00 ATOM 272 QB GLN 138-0.665 4.176-5.368 1.00 0.00 ATOM 273 CG GLN 138 0.898 4.744-6.354 1.00 0.00 ATOM 274 1HG GLN 138 1.382 5.702-6.232 1.00 0.00 ATOM 275 2HG GLN 138 0.496 4.669-7.354 1.00 0.00 ATOM 276 QG GLN 138 0.939 5.186-6.793 1.00 0.00 ATOM 277 CD GLN 138 1.932 3.651-6.169 1.00 0.00 ATOM 278 OE1 GLN 138 1.737 2.517-6.600 1.00 0.00 ATOM 279 NE2 GLN 138 3.040 3.985-5.524 1.00 0.00 ATOM 280 1HE2 GLN 138 3.132 4.909-5.204 1.00 0.00 ATOM 281 2HE2 GLN 138 3.720 3.296-5.390 1.00 0.00 ATOM 282 QE2 GLN 138 3.426 4.103-5.297 1.00 0.00 ATOM 283 C GLN 138-1.715 6.080-3.942 1.00 0.00 ATOM 284 O GLN 138-2.302 5.396-3.103 1.00 0.00 ATOM 285 N GLU 139-2.277 7.099-4.567 1.00 0.00 ATOM 286 H GLU 139-1.756 7.596-5.230 1.00 0.00 ATOM 287 CA GLU 139-3.649 7.498-4.305 1.00 0.00 ATOM 288 HA GLU 139-3.958 7.040-3.373 1.00 0.00 ATOM 289 CB GLU 139-3.741 9.024-4.176 1.00 0.00 ATOM 290 1HB GLU 139-4.186 9.269-3.222 1.00 0.00 ATOM 291 2HB GLU 139-4. 376 9.401-4.964 1.00 0.00 ATOM 292 QB GLU 139-4.281 9.335-4.093 1.00 0.00 ATOM 293 CG GLU 139-2.397 9.735-4.268 1.00 0.00 ATOM 294 1HG GLU 139-2.370 10.310-5.183 1.00 0.00 ATOM 295 2HG GLU 139-1.611 8.996-4.284 1.00 0.00 ATOM 296 QG GLU 139-1.990 9.653-4.733 1.00 0.00 ATOM 297 CD GLU 139-2.152 10.670-3.104 1.00 0.00 ATOM 298 OE1 GLU 139-3.121 11.294-2.632 1.00 0.00 ATOM 299 OE2 GLU 139-0.991 10.766-2.656 1.00 0.00 ATOM 300 C GLU 139-4.559 7.009-5.431 1.00 0.00 ATOM 301 O GLU 139-4.614 7.610-6.502 1.00 0.00 ATOM 302 N ARG+ 140-5.263 5.913-5.188 1.00 0.00 ATOM 303 H ARG+ 140-5.180 5.472-4.315 1.00 0.00 ATOM 304 CA ARG+ 140-6.163 5.345-6.185 1.00 0.00 ATOM 305 HA ARG+ 140-5.865 5.717-7.154 1.00 0.00 ATOM 306 CB ARG+ 140-6.057 3.813-6.177 1.00 0.00 ATOM 307 1HB ARG+ 140-6.606 3.436-5.325 1.00 0.00 ATOM 308 2HB ARG+ 140-5.019 3.536-6.075 1.00 0.00 ATOM 309 QB ARG+ 140-5.812 3.486-5.700 1.00 0.00 ATOM 310 CG ARG+ 140-6.608 3.146-7.428 1.00 0.00 ATOM 311 1HG ARG+ 140-7.515 3.656-7.724 1.00 0.00 ATOM 312 2HG ARG+ 140-6. 831 2.114-7.203 1.00 0.00 ATOM 313 QG ARG+ 140-7.173 2.885-7.463 1.00 0.00 ATOM 314 CD ARG+ 140-5.615 3.198-8.578 1.00 0.00 ATOM 315 1HD ARG+ 140-4.615 3.258-8.173 1.00 0.00 ATOM 316 2HD ARG+ 140-5.816 4.083-9.168 1.00 0.00 ATOM 317 QD ARG+ 140-5.215 3.671-8.670 1.00 0.00 ATOM 318 NE ARG+ 140-5.711 2.019-9.441 1.00 0.00 ATOM 319 HE ARG+ 140-5. 174 1.236-9.194 1.00 0.00 ATOM 320 CZ ARG+ 140-6.475 1.960-10.534 1.00 0.00 ATOM 321 NH1 ARG+ 140-7.231 2.996-10.873 1.00 0.00 ATOM 322 1HH1 ARG+ 140-7.235 3.833-10.302 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.806 2.959-11.690 1.00 0.00 ATOM 324 QH1 ARG+ 140-7.520 3.396-10.996 1.00 0.00 ATOM 325 NH2 ARG+ 140-6.491 0.858-11.277 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.931 0.070-11.019 1.00 0.00 ATOM 327 2HH2 ARG+ 140-7.065 0.813-12.096 1.00 0.00 ATOM 328 QH2 ARG+ 140-6.498 0.442-11.557 1.00 0.00 ATOM 329 C ARG+ 140-7.601 5.774-5.909 1.00 0.00 ATOM 330 O ARG+ 140-8.392 5.003-5.367 1.00 0.00 ATOM 331 N MET 141-7.936 7.008-6.286 1.00 0.00 ATOM 332 H MET 141-7.260 7.572-6.717 1.00 0.00 ATOM 333 CA MET 141-9.285 7.547-6.076 1.00 0.00 ATOM 334 HA MET 141-9.577 7.318-5.061 1.00 0.00 ATOM 335 CB MET 141-9.277 9.070-6.256 1.00 0.00 ATOM 336 1HB MET 141-9.449 9.296-7.299 1.00 0.00 ATOM 337 2HB MET 141-8.307 9.450-5. 970 1.00 0.00 ATOM 338 QB MET 141-8.878 9.373-6. 634 1.00 0.00 ATOM 339 CG MET 141-10.333 9.789-5.433 1.00 0.00 ATOM 340 1HG MET 141-10.448 9.273-4.491 1.00 0.00 ATOM 341 2HG MET 141-11.268 9.762-5. 972 1.00 0.00 ATOM 342 QG MET 141-10. 858 9.518-5.231 1.00 0.00

ATOM 343 SD MET 141-9.909 11.510-5.102 1.00 0.00 ATOM 344 QE MET 141-10.423 12.429-6.978 1.00 0.00 ATOM 345 CE MET 141-10.338 12.274-6.664 1.00 0.00 ATOM 346 1HE MET 141-11.322 12.713-6.593 1.00 0.00 ATOM 347 2HE MET 141-10.331 11.528-7. 445 1.00 0.00 ATOM 348 3HE MET 141-9.617 13.045-6. 897 1.00 0.00 ATOM 349 C MET 141-10.304 6.918-7.031 1.00 0.00 ATOM 350 O MET 141-11.319 7.532-7.368 1.00 0.00 ATOM 351 N ASP 142-10.027 5.695-7.451 1.00 0.00 ATOM 352 H ASP 142-9.209 5.263-7.135 1.00 0.00 ATOM 353 CA ASP 142-10.894 4.969-8.358 1.00 0.00 ATOM 354 HA ASP 142-11.612 5.664-8.766 1.00 0.00 ATOM 355 CB ASP 142-10.078 4.362-9.499 1.00 0. 00 ATOM 356 1HB ASP 142-10.740 4.145-10.316 1.00 0.00 ATOM 357 2HB ASP 142-9.625 3.444-9.159 1.00 0.00 ATOM 358 QB ASP 142-10.182 3.795-9. 737 1.00 0.00 ATOM 359 CG ASP 142-8.983 5.276-10.002 1.00 0.00 ATOM 360 OD1 ASP 142-7.863 5.218-9. 449 1.00 0.00 ATOM 361 OD2 ASP 142-9.228 6.021-10.965 1.00 0.00 ATOM 362 C ASP 142-11.630 3.861-7. 625 1.00 0.00 ATOM 363 O ASP 142-12.844 3.708-7.756 1.00 0.00 ATOM 364 N VAL 143-10.884 3.074-6.859 1.00 0.00 ATOM 365 H VAL 143-9.921 3.238-6.797 1.00 0.00 ATOM 366 CA VAL 143-11.471 1.969-6.120 1.00 0.00 ATOM 367 HA VAL 143-12.390 1.698-6. 621 1.00 0.00 ATOM 368 CB VAL 143-10.543 0.734-6.115 1.00 0.00 ATOM 369 HB VAL 143-9.943 0.762-5.215 1.00 0.00 ATOM 370 QG1 VAL 143-11.553-0.855-6.099 1.00 0.00 ATOM 371 QG2 VAL 143-9.385 0.756-7. 598 1.00 0. 00 ATOM 372 CG1 VAL 143-11.361-0.551-6.102 1.00 0.00 ATOM 373 1HG1 VAL 143-11.661-0.778-5.089 1.00 0.00 ATOM 374 2HG1 VAL 143-10. 761-1.362-6.489 1.00 0.00 ATOM 375 3HG1 VAL 143-12.238-0.426-6.719 1.00 0.00 ATOM 376 CG2 VAL 143-9.605 0.751-7.315 1.00 0.00 ATOM 377 1HG2 VAL 143-9.944 1.493-8. 024 1.00 0.00 ATOM 378 2HG2 VAL 143-9.604-0.221-7.784 1.00 0.00 ATOM 379 3HG2 VAL 143-8.606 0.996-6.987 1.00 0.00 ATOM 380 QQG VAL 143-10.469-0.049-6.849 1.00 0.00 ATOM 381 C VAL 143-11.805 2.397-4. 689 1.00 0.00 ATOM 382 O VAL 143-11.315 3.416-4.203 1.00 0.00 ATOM 383 N CYS 144-12.672 1.639-4. 031 1.00 0.00 ATOM 384 H CYS 144-13. 053 0.852-4.475 1.00 0. 00 ATOM 385 CA CYS 144-13.103 1.966-2.674 1.00 0.00 ATOM 386 HA CYS 144-12.325 2.550-2.191 1.00 0. 00 ATOM 387 CB CYS 144-14.383 2.800-2.768 1.00 0.00 ATOM 388 1HB CYS 144-15. 119 2.243-3. 332 1.00 0. 00 ATOM 389 2HB CYS 144-14.164 3.718-3.291 1.00 0.00 ATOM 390 QB CYS 144-14.641 2.981-3.311 1.00 0. 00 ATOM 391 SG CYS 144-15.135 3.246-1.175 1.00 0.00 ATOM 392 C CYS 144-13.353 0.704-1. 861 1.00 0.00 ATOM 393 O CYS 144-14.401 0.076-1.999 1.00 0.00 ATOM 394 N GLU 145-12.391 0.333-1.022 1.00 0.00 ATOM 395 H GLU 145-11.574 0.866-0.957 1.00 0.00 ATOM 396 CA GLU 145-12.519-0.861-0.203 1. 00 0.00 ATOM 397 HA GLU 145-13.562-1.133-0.176 1.00 0.00 ATOM 398 CB GLU 145-11.743-2.004-0.831 1.00 0.00 ATOM 399 1HB GLU 145-11.444-2.686-0. 055 1.00 0. 00 ATOM 400 2HB GLU 145-10.858-1.606-1.306 1.00 0.00 ATOM 401 QB GLU 145-11. 151-2. 146-0.680 1.00 0.00 ATOM 402 CG GLU 145-12.554-2.776-1. 860 1.00 0.00 ATOM 403 1HG GLU 145-11.903-3.475-2.363 1.00 0.00 ATOM 404 2HG GLU 145-12.958-2.080-2.580 1.00 0.00 ATOM 405 QG GLU 145-12.430-2.777-2. 471 1.00 0.00 ATOM 406 CD GLU 145-13. 706-3.548-1.237 1.00 0.00 ATOM 407 OE1 GLU 145-14. 253-4.440-1.913 1.00 0.00 ATOM 408 OE2 GLU 145-14.053-3.267-0. 067 1.00 0.00 ATOM 409 C GLU 145-12.037-0.630 1.221 1.00 0.00 ATOM 410 O GLU 145-11.544 0.448 1. 555 1.00 0.00 ATOM 411 N THR 146-12.191-1.653 2.052 1.00 0.00 ATOM 412 H THR 146-12.593-2.481 1.711 1.00 0.00 ATOM 413 CA THR 146-11.790-1.587 3.451 1.00 0.00 ATOM 414 HA THR 146-12. 101-0.627 3.837 1.00 0.00

ATOM 415 CB THR 146-12.505-2.693 4.241 1.00 0.00 ATOM 416 HB THR 146-12.041-3.642 4.012 1.00 0.00 ATOM 417 QG2 THR 146-12.455-2.461 6.102 1.00 0.00 ATOM 418 OG1 THR 146-13.868-2.762 3.868 1.00 0.00 ATOM 419 1HG THR 146-14.416-2.377 4.577 1.00 0.00 ATOM 420 CG2 THR 146-12.463-2.507 5.744 1.00 0.00 ATOM 421 lHG2 THR 146-11.446-2.601 6.093 1.00 0.00 ATOM 422 2HG2 THR 146-13.078-3.259 6.217 1.00 0.00 ATOM 423 3HG2 THR 146-12.840-1.525 5.996 1.00 0.00 ATOM 424 C THR 146-10.272-1.708 3.604 1.00 0.00 ATOM 425 O THR 146-9. 569-2.099 2.671 1.00 0.00 ATOM 426 N HIS+ 147-9.784-1.369 4.798 1.00 0.00 ATOM 427 H HIS+ 147-10.411-1.067 5. 490 1.00 0.00 ATOM 428 CA HIS+ 147-8. 358-1.426 5.121 1.00 0.00 ATOM 429 HA HIS+ 147-7.848-0.699 4.508 1.00 0.00 ATOM 430 CB HIS+ 147-8.150-1.066 6.596 1.00 0.00 ATOM 431 1HB HIS+ 147-8.125-1.977 7.178 1.00 0.00 ATOM 432 2HB HIS+ 147-8.977-0.458 6.930 1.00 0.00 ATOM 433 QB HIS+ 147-8.551-1.217 7.054 1.00 0.00 ATOM 434 CG HIS+ 147-6. 887-0.310 6.872 1.00 0.00 ATOM 435 ND1 HIS+ 147-6.837 1.065 6.969 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.623-0.746 7.094 1.00 0.00 ATOM 437 1HD HIS+ 147-7.598 1.679 6.851 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.599 1.442 7.240 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.842 0.362 7.321 1.00 0.00 ATOM 440 2HD HIS+ 147-5.286-1.776 7.078 1.00 0.00 ATOM 441 1HE HIS+ 147-5.263 2.461 7.373 1.00 0.00 ATOM 442 2HE HIS+ 147-3.912 0.348 7.636 1.00 0.00 ATOM 443 C HIS+ 147-7.769-2.809 4.844 1.00 0.00 ATOM 444 O HIS+ 147-6.610-2.928 4.457 1.00 0.00 ATOM 445 N LEU 148-8.570-3.850 5.045 1.00 0.00 ATOM 446 H LEU 148-9.487-3.695 5.352 1.00 0.00 ATOM 447 CA LEU 148-8.113-5.217 4.814 1.00 0.00 ATOM 448 HA LEU 148-7.163-5.338 5.311 1.00 0.00 ATOM 449 CB LEU 148-9.113-6.220 5.396 1.00 0.00 ATOM 450 1HB LEU 148-9.847-6.446 4.637 1.00 0.00 ATOM 451 2HB LEU 148-9.614-5.755 6.232 1.00 0.00 ATOM 452 QB LEU 148-9.730-6.100 5.435 1.00 0.00 ATOM 453 CG LEU 148-8.501-7.538 5.874 1.00 0.00 ATOM 454 HG LEU 148-7.427-7.435 5.918 1.00 0.00 ATOM 455 QD1 LEU 148-9.115-7.967 7.598 1.00 0.00 ATOM 456 QD2 LEU 148-8.903-8.927 4.672 1.00 0.00 ATOM 457 CD1 LEU 148-8.997-7.884 7.267 1.00 0.00 ATOM 458 1HD1 LEU 148-10.046-8.139 7.224 1.00 0.00 ATOM 459 2HD1 LEU 148-8.859-7.036 7.921 1.00 0.00 ATOM 460 3HD1 LEU 148-8.439-8.726 7.648 1.00 0.00 ATOM 461 CD2 LEU 148-8.827-8.661 4.902 1.00 0.00 ATOM 462 1HD2 LEU 148-8.677-9.613 5.389 1.00 0.00 ATOM 463 2HD2 LEU 148-8.177-8.592 4.041 1.00 0.00 ATOM 464 3HD2 LEU 148-9. 855-8. 577 4.585 1.00 0.00 ATOM 465 QQD LEU 148-9.009-8.447 6.135 1.00 0.00 ATOM 466 C LEU 148-7.924-5.480 3.325 1.00 0.00 ATOM 467 O LEU 148-6.977-6.149 2.920 1.00 0.00 ATOM 468 N HIS+ 149-8.832-4.946 2.519 1.00 0.00 ATOM 469 H HIS+ 149-9.560-4.419 2.906 1.00 0.00 ATOM 470 CA HIS+ 149-8.774-5.117 1.073 1.00 0.00 ATOM 471 HA HIS+ 149-8.770-6.178 0.868 1.00 0.00 ATOM 472 CB HIS+ 149-10. 003-4. 494 0.423 1.00 0.00 ATOM 473 1HB HIS+ 149-9.712-3.996-0.491 1.00 0.00 ATOM 474 2HB HIS+ 149-10.429-3.768 1.098 1.00 0.00 ATOM 475 QB HIS+ 149-10.070-3.882 0.304 1.00 0.00 ATOM 476 CG HIS+ 149-11. 069-5. 488 0.088 1.00 0.00 ATOM 477 ND1 HIS+ 149-11. 912-6. 035 1.028 1.00 0.00 ATOM 478 CD2 HIS+ 149-11.449-6.006-1.102 1.00 0.00 ATOM 479 1HD HIS+ 149-11. 895-5. 850 1.990 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.767-6.845 0.431 1.00 0.00 ATOM 481 NE2 HIS+ 149-12. 513-6. 845-0.868 1.00 0.00 ATOM 482 2HD HIS+ 149-11. 005-5. 791-2.064 1.00 0.00 ATOM 483 1HE HIS+ 149-13. 549-7. 407 0.919 1.00 0.00 ATOM 484 2HE HIS+ 149-13. 167-7. 105-1.553 1.00 0.00 ATOM 485 C HIS+ 149-7. 502-4. 508 0.502 1.00 0.00 ATOM 486 O HIS+ 149-6. 727-5.197-0.157 1.00 0.00

ATOM 487 N TRP 150-7.282-3.222 0.770 1.00 0.00 ATOM 488 H TRP 150-7. 937-2.725 1.308 1.00 0.00 ATOM 489 CA TRP 150-6.081-2.534 0.288 1.00 0.00 ATOM 490 HA TRP 150-6. 056-2.611-0.789 1.00 0.00 ATOM 491 CB TRP 150-6.090-1.060 0.694 1.00 0.00 ATOM 492 1HB TRP 150-5.133-0.623 0.440 1.00 0.00 ATOM 493 2HB TRP 150-6. 234-0.990 1.760 1.00 0.00 ATOM 494 QB TRP 150-5.683-0.806 1.100 1.00 0.00 ATOM 495 CG TRP 150-7.157-0.238 0.036 1.00 0.00 ATOM 496 CD1 TRP 150-7. 628 0.968 0.466 1.00 0.00 ATOM 497 CD2 TRP'150-7. 882-0.545-1.161 1.00 0.00 ATOM 498 CE3 TRP 150-7.868-1.614-2.062 1.00 0.00 ATOM 499 CE2 TRP 150-8. 771 0.520-1.391 1.00 0.00 ATOM 500 NE1 TRP 150-8.598 1.428-0.385 1.00 0.00 ATOM 501 HD TRP 150-7.278 1.475 1.353 1.00 0.00 ATOM 502 3HE TRP 150-7. 202-2.451-1.924 1.00 0.00 ATOM 503 CZ3 TRP 150-8.725-1. 586-3.139 1.00 0.00 ATOM 504 CZ2 TRP 150-9.631 0.546-2.478 1.00 0.00 ATOM 505 1HE TRP 150-9. 088 2.273-0.287 1.00 0.00 ATOM 506 3HZ TRP 150-8.731-2.405-3.842 1.00 0.00 ATOM 507 CH2 TRP 150-9.594-0.513-3.338 1.00 0.00 ATOM 508 2HZ TRP 150-10.311 1.368-2.652 1.00 0.00 ATOM 509 HH TRP 150-10. 250-0.535-4.195 1.00 0.00 ATOM 510 C TRP 150-4.835-3.200 0.829 1.00 0.00 ATOM 511 O TRP 150-3.816-3.245 0.152 1.00 0.00 ATOM 512 N HIS+ 151-4. 926-3.741 2.038 1.00 0.00 ATOM 513 H HIS+ 151-5.774-3.692 2.526 1.00 0.00 ATOM 514 CA HIS+ 151-3.797-4.433 2.631 1.00 0.00 ATOM 515 HA HIS+ 151-2.958-3.753 2.641 1.00 0.00 ATOM 516 CB HIS+ 151-4.115-4.875 4.068 1.00 0.00 ATOM 517 1HB HIS+ 151-4.916-5.602 4.042 1.00 0.00 ATOM 518 2HB HIS+ 151-4.437-4.016 4.637 1.00 0.00 ATOM 519 QB HIS+ 151-4.676-4.809 4.340 1.00 0.00 ATOM 520 CG HIS+ 151-2.951-5.496 4.788 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.966-5.797 6.134 1.00 0.00 ATOM 522 CD2 HIS+ 151-1.735-5.878 4.335 1.00 0.00 ATOM 523 1HD HIS+ 151-3.714-5.641 6.751 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.806-6.336 6.473 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.043-6.396 5.400 1.00 0.00 ATOM 526 2HD HIS+ 151-1.386-5.807 3.310 1.00 0.00 ATOM 527 1HE HIS+ 151-1.525-6.663 7.463 1.00 0.00 ATOM 528 2HE HIS+ 151-0.088-6.622 5.401 1.00 0.00 ATOM 529 C HIS+ 151-3.449-5.640 1.770 1.00 0.00 ATOM 530 O HIS+ 151-2.290-5.851 1.433 1.00 0.00 ATOM 531 N THR 152-4.464-6.415 1.413 1.00 0.00 ATOM 532 H THR 152-5. 370-6.185 1.711 1.00 0.00 ATOM 533 CA THR 152-4.270-7.595 0.585 1.00 0.00 ATOM 534 HA THR 152-3.522-8.211 1.062 1.00 0.00 ATOM 535 CB THR 152-5.574-8.393 0.476 1.00 0.00 ATOM 536 HB THR 152-6.227-7.902-0.231 1.00 0.00 ATOM 537 QG2 THR 152-5.320-10.157-0.106 1.00 0.00 ATOM 538 OG1 THR 152-6.236-8.454 1.731 1.00 0.00 ATOM 539 1HG THR 152-6.453-7.564 2.030 1.00 0.00 ATOM 540 CG2 THR 152-5.369-9.817 0.006 1.00 0.00 ATOM 541 1HG2 THR 152-4.333-9.962-0.267 1.00 0.00 ATOM 542 2HG2 THR 152-5.996-10.008-0.852 1.00 0.00 ATOM 543 3HG2 THR 152-5.630-10.501 0.801 1.00 0.00 ATOM 544 C THR 152-3.762-7.212-0.802 1.00 0.00 ATOM 545 O THR 152-2.848-7.839-1.315 1.00 0.00 ATOM 546 N VAL 153-4.336-6.171-1.399 1.00 0.00 ATOM 547 H VAL 153-5.052-5.683-0.936 1.00 0.00 ATOM 548 CA VAL 153-3.896-5.731-2.723 1.00 0.00 ATOM 549 HA VAL 153-3.969-6.569-3.395 1.00 0.00 ATOM 550 CB VAL 153-4.770-4.576-3.267 1.00 0.00 ATOM 551 HB VAL 153-4.622-3.712-2.635 1.00 0.00 ATOM 552 QG1 VAL 153-4.260-4.113-5.018 1.00 0.00 ATOM 553 QG2 VAL 153-6.592-5.038-3.218 1.00 0.00 ATOM 554 CG1 VAL 153-4.358-4.202-4.683 1.00 0.00 ATOM 555 1HG1 VAL 153-5.033-4.664-5.388 1.00 0.00 ATOM 556 2HG1 VAL 153-3.351-4.548-4.868 1.00 0.00 ATOM 557 3HG1 VAL 153-4.396-3.129-4.797 1. 00 0.00 ATOM 558 CG2 VAL 153-6.243-4.950-3.227 1.00 0.00

ATOM 559 1HG2 VAL 153-6.401-5.852-3.800 1.00 0.00 ATOM 560 2HG2 VAL 153-6.829-4. 148-3. 650 1.00 0.00 ATOM 561 3HG2 VAL 153-6.545-5.116-2.203 1.00 0.00 ATOM 562 QQG VAL 153-5.426-4.576-4.118 1.00 0.00 ATOM 563 C VAL 153-2.446-5.294-2.664 1.00 0.00 ATOM 564 O VAL 153-1.610-5.763-3.435 1.00 0.00 ATOM 565 N ALA 154-2.161-4.411-1.729 1.00 0.00 ATOM 566 H ALA 154-2.889-4.092-1.142 1.00 0.00 ATOM 567 CA ALA 154-0.814-3.904-1.523 1.00 0.00 ATOM 568 HA ALA 154-0.501-3.383-2.415 1.00 0.00 ATOM 569 QB ALA 154-0.826-2.690-0.095 1.00 0.00 ATOM 570 CB ALA 154-0. 824-2.924-0.369 1.00 0.00 ATOM 571 1HB ALA 154-1.842-2.642-0.143 1.00 0.00 ATOM 572 2HB ALA 154-0.258-2.043-0.641 1.00 0.00 ATOM 573 3HB ALA 154-0.377-3.385 0.499 1.00 0.00 ATOM 574 C ALA 154 0.171-5.031-1.233 1.00 0.00 ATOM 575 O ALA 154 1.235-5.119-1.850 1.00 0.00 ATOM 576 N LYS+ 155-0.186-5.881-0.280 1.00 0.00 ATOM 577 H LYS+ 155-1.045-5.748 0.179 1.00 0.00 ATOM 578 CA LYS+ 155 0.661-6.997 0.116 1.00 0.00 ATOM 579 HA LYS+ 155 1.619-6.597 0.429 1.00 0.00 ATOM 580 CB LYS+ 155 0.023-7.763 1.282 1.00 0.00 ATOM 581 1HB LYS+ 155-0.592-8.556 0.877 1.00 0.00 ATOM 582 2HB LYS+ 155-0.607-7.085 1.837 1.00 0.00 ATOM 583 QB LYS+ 155-0.599-7.820 1.357 1.00 0.00 ATOM 584 CG LYS+ 155 1.022-8.384 2.251 1.00 0.00 ATOM 585 1HG LYS+ 155 0.522-8.571 3.191 1.00 0.00 ATOM 586 2HG LYS+ 155 1.833-7.689 2.408 1.00 0.00 ATOM 587 QG LYS+ 155 1.178-8.130 2.800 1.00 0.00 ATOM 588 CD LYS+ 155 1.595-9.693 1.730 1.00 0.00 ATOM 589 1HD LYS+ 155 2.419-9.989 2.363 1.00 0.00 ATOM 590 2HD LYS+ 155 1.951-9.541 0.721 1.00 0.00 ATOM 591 QD LYS+ 155 2.185-9.765 1.542 1.00 0.00 ATOM 592 CE LYS+ 155 0.553-10.804 1.722 1.00 0.00 ATOM 593 1HE LYS+ 155-0.417-10.369 1.519 1.00 0.00 ATOM 594 2HE LYS+ 155 0.539-11.276 2.693 1.00 0.00 ATOM 595 QE LYS+ 155 0.061-10.822 2.106 1.00 0.00 ATOM 596 NZ LYS+ 155 0.846-11.832 0.687 1.00 0.00 ATOM 597 1HZ LYS+ 155 1.826-11.733 0.343 1.00 0.00 ATOM 598 2HZ LYS+ 155 0.189-11.716-0.130 1.00 0.00 ATOM 599 3HZ LYS+ 155 0.717-12.784 1.076 1.00 0.00 ATOM 600 QZ LYS+ 155 0.911-12.077 0.430 1.00 0.00 ATOM 601 C LYS+ 155 0.891-7.933-1.054 1.00 0.00 ATOM 602 O LYS+ 155 2.029-8.293-1.324 1.00 0.00 ATOM 603 N GLU 156-0.181-8.331-1.737 1.00 0.00 ATOM 604 H GLU 156-1.077-8.020-1.468 1.00 0.00 ATOM 605 CA GLU 156-0.064-9.234-2.871 1. 00 0.00 ATOM 606 HA GLU 156 0.401-10.141-2.511 1.00 0.00 ATOM 607 CB GLU 156-1.441-9.587-3.428 1.00 0.00 ATOM 608 1HB GLU 156-1. 318-10.025-4.407 1.00 0.00 ATOM 609 2HB GLU 156-2.024-8.682-3.517 1.00 0.00 ATOM 610 QB GLU 156-1.671-9.353-3.962 1.00 0.00 ATOM 611 CG GLU 156-2.215-10.572-2.556 1.00 0.00 ATOM 612 1HG GLU 156-2.534-11.395-3.169 1.00 0.00 ATOM 613 2HG GLU 156-3.083-10.070-2.157 1.00 0.00 ATOM 614 QG GLU 156-2.808-10.732-2.663 1.00 0. 00 ATOM 615 CD GLU 156-1.403-11.118-1.398 1.00 0.00 ATOM 616 OE1 GLU 156-1.698-10.760-0.243 1.00 0.00 ATOM 617 OE2 GLU 156-0.455-11.895-1.639 1.00 0.00 ATOM 618 C GLU 156 0.827-8.645-3.954 1.00 0.00 ATOM 619 0 GLU 156 1.672-9.342-4.492 1.00 0.00 ATOM 620 N THR 157 0.658-7.358-4.251 1.00 0.00 ATOM 621 H THR 157-0.030-6.840-3.772 1.00 0.00 ATOM 622 CA THR 157 1.491-6.696-5.259 1.00 0. 00 ATOM 623 HA THR 157 1.294-7.170-6.210 1.00 0.00 ATOM 624 CB THR 157 1.131-5.206-5.353 1.00 0.00 ATOM 625 HB THR 157 1.395-4.723-4.422 1.00 0.00 ATOM 626 QG2 THR 157 2.013-4.302-6.739 1.00 0.00 ATOM 627 OG1 THR 157-0.260-5. 035-5.564 1.00 0.00 ATOM 628 1HG THR 157-0.750-5.415-4.821 1.00 0.00 ATOM 629 CG2 THR 157 1.844-4.476-6.472 1.00 0.00 ATOM 630 1HG2 THR 157 1.196-3.710-6.873 1.00 0.00

ATOM 631 2HG2 THR 157 2.098-5.177-7.255 1.00 0.00 ATOM 632 3HG2 THR 157 2.745-4.021-6.089 1.00 0.00 ATOM 633 C THR 157 2.980-6.871-4.922 1.00 0.00 ATOM 634 O THR 157 3.812-7.092-5.801 1.00 0.00 ATOM 635 N CYS 158 3.305-6.783-3.637 1.00 0.00 ATOM 636 H CYS 158 2.596-6.605-2.974 1.00 0.00 ATOM 637 CA CYS 158 4.684-6.944-3.181 1.00 0.00 ATOM 638 HA CYS 158 5.336-6.494-3.915 1.00 0.00 ATOM 639 CB CYS 158 4.862-6.211-1.855 1.00 0.00 ATOM 640 1HB CYS 158 5.758-6.553-1.373 1.00 0. 00 ATOM 641 2HB CYS 158 4.017-6.431-1.222 1.00 0.00 ATOM 642 QB CYS 158 4.888-6.492-1.297 1.00 0.00 ATOM 643 SG CYS 158 4.967-4.395-2. 039 1.00 0.00 ATOM 644 C CYS 158 5.062-8.426-3. 051 1.00 0.00 ATOM 645 O CYS 158 6.149-8.831-3.469 1.00 0.00 ATOM 646 N SER 159 4.167-9.222-2. 467 1.00 0.00 ATOM 647 H SER 159 3.327-8.831-2.147 1.00 0.00 ATOM 648 CA SER 159 4.388-10.657-2.270 1.00 0.00 ATOM 649 HA SER 159 5.321-10.777-1.741 1.00 0.00 ATOM 650 CB SER 159 3.263-11.255-1.428 1.00 0.00 ATOM 651 1HB SER 159 3.067-12.265-1.762 1.00 0.00 ATOM 652 2HB SER 159 2.370-10.658-1. 551 1.00 0.00 ATOM 653 QB SER 159 2.719-11.461-1.656 1.00 0.00 ATOM 654 OG SER 159 3.608-11.286-0. 050 1.00 0.00 ATOM 655 HG SER 159 4.522-11.581 0.041 1.00 0.00 ATOM 656 C SER 159 4.478-11.417-3. 594 1.00 0.00 ATOM 657 O SER 159 5.152-12.441-3.669 1.00 0.00 ATOM 658 N GLU 160 3.795-10.921-4.627 1.00 0.00 ATOM 659 H GLU 160 3.264-10.102-4.505 1.00 0.00 ATOM 660 CA GLU 160 3.810-11.563-5.940 1.00 0.00 ATOM 661 HA GLU 160 3.495-12.589-5.817 1.00 0.00 ATOM 662 CB GLU 160 2.851-10.844-6.897 1.00 0.00 ATOM 663 1HB GLU 160 3.393-10.065-7.414 1.00 0.00 ATOM 664 2HB GLU 160 2.057-10.393-6.322 1.00 0.00 ATOM 665 QB GLU 160 2.725-10.229-6.868 1.00 0.00 ATOM 666 CG GLU 160 2.220-11.752-7.940 1.00 0.00 ATOM 667 1HG GLU 160 1.612-12.490-7.438 1.00 0.00 ATOM 668 2HG GLU 160 3.003-12.246-8.493 1.00 0.00 ATOM 669 QG GLU 160 2.308-12.368-7.965 1.00 0.00 ATOM 670 CD GLU 160 1.347-10.989-8.915 1.00 0.00 ATOM 671 OE1 GLU 160 1.772-9.904-9.366 1.00 0.00 ATOM 672 OE2 GLU 160 0.240-11.474-9.226 1.00 0.00 ATOM 673 C GLU 160 5.231-11.541-6.492 1.00 0.00 ATOM 674 O GLU 160 5.649-12.424-7.244 1.00 0.00 ATOM 675 N LYS+ 161 5.978-10.533-6. 067 1.00 0.00 ATOM 676 H LYS+ 161 5.587-9.888-5.444 1.00 0.00 ATOM 677 CA LYS+ 161 7.363-10.379-6. 452 1.00 0.00 ATOM 678 HA LYS+ 161 7.515-10.913-7.379 1.00 0.00 ATOM 679 CB LYS+ 161 7.709-8.895-6. 646 1.00 0.00 ATOM 680 1HB LYS+ 161 8.071-8.499-5.709 1.00 0.00 ATOM 681 2HB LYS+ 161 6.811-8.365-6. 924 1.00 0.00 ATOM 682 QB LYS+ 161 7.441-8.432-6. 316 1.00 0.00 ATOM 683 CG LYS+ 161 8.768-8.641-7.715 1.00 0. 00 ATOM 684 1HG LYS+ 161 8.330-8.036-8. 498 1.00 0.00 ATOM 685 2HG LYS+ 161 9.081-9.588-8.126 1.00 0. 00 ATOM 686 QG LYS+ 161 8.706-8.812-8.312 1.00 0.00 ATOM 687 CD LYS+ 161 9.986-7.917-7. 152 1.00 0.00 ATOM 688 1HD LYS+ 161 10.026-8.075-6. 084 1.00 0.00 ATOM 689 2HD LYS+ 161 9.887-6.859-7.355 1.00 0.00 ATOM 690 QD LYS+ 161 9.957-7.467-6.719 1.00 0.00 ATOM 691 CE LYS+ 161 11.285-8.416-7. 777 1.00 0.00 ATOM 692 1HE LYS+ 161 12.098-8.218-7.091 1.00 0. 00 ATOM 693 2HE LYS+ 161 11.455-7.878-8.699 1.00 0.00 ATOM 694 QE LYS+ 161 11.777-8.048-7.895 1.00 0.00 ATOM 695 NZ LYS+ 161 11.246-9.878-8.071 1.00 0.00 ATOM 696 1HZ LYS+ 161 11.336-10.429-7.181 1.00 0.00 ATOM 697 2HZ LYS+ 161 12.030-10.138-8.703 1.00 0.00 ATOM 698 3HZ LYS+ 161 10.349-10.130-8. 530 1.00 0.00 ATOM 699 QZ LYS+ 161 11.238-10.232-8.138 1.00 0.00 ATOM 700 C LYS+ 161 8.232-11.003-5. 364 1.00 0.00 ATOM 701 O LYS+ 161 7.927-12.075-4.855 1.00 0.00 ATOM 702 N SER 162 9.303-10.329-4.998 1.00 0.00

ATOM 703 H SER 162 9.498-9.475-5.420 1.00 0.00 ATOM 704 CA SER 162 10.180-10.831-3.961 1.00 0.00 ATOM 705 HA SER 162 9.776-11.770-3.616 1.00 0.00 ATOM 706 CB SER 162 11.587-11.068-4.514 1.00 0.00 ATOM 707 1HB SER 162 12.054-11.875-3.963 1.00 0.00 ATOM 708 2HB SER 162 12.173-10.169-4.395 1.00 0.00 ATOM 709 QB SER 162 12.114-11.022-4.179 1.00 0.00 ATOM 710 OG SER 162 11.543-11.416-5.894 1.00 0.00 ATOM 711 HG SER 162 11.508-12.379-5.970 1.00 0.00 ATOM 712 C SER 162 10.232-9.863-2.786 1.00 0.00 ATOM 713 O SER 162 11.309-9.487-2.338 1.00 0.00 ATOM 714 N THR 163 9.068-9.445-2.288 1.00 0.00 ATOM 715 H THR 163 8.223-9.759-2.684 1.00 0.00 ATOM 716 CA THR 163 9.030-8.526-1.157 1.00 0.00 ATOM 717 HA THR 163 9.939-8.671-0.587 1.00 0.00 ATOM 718 CB THR 163 8.967-7.067-1. 613 1.00 0.00 ATOM 719 HB THR 163 8.847-6.449-0.729 1.00 0.00 ATOM 720 QG2 THR 163 10.495-6.472-2.520 1.00 0.00 ATOM 721 OG1 THR 163 7.859-6.849-2.466 1.00 0.00 ATOM 722 1HG THR 163 7.563-7.693-2. 834 1.00 0.00 ATOM 723 CG2 THR 163 10.201-6.586-2.346 1.00 0.00 ATOM 724 1HG2 THR 163 10.700-5.831-1.756 1.00 0.00 ATOM 725 2HG2 THR 163 9.915-6.166-3.299 1.00 0.00 ATOM 726 3HG2 THR 163 10.871-7.419-2.506 1.00 0.00 ATOM 727 C THR 163 7.842-8.817-0.245 1.00 0.00 ATOM 728 O THR 163 6.856-9.429-0.651 1.00 0.00 ATOM 729 N ASN 164 7.948-8.361 0.991 1.00 0.00 ATOM 730 H ASN 164 8.769-7.878 1.247 1.00 0.00 ATOM 731 CA ASN 164 6.889-8.550 1.988 1.00 0.00 ATOM 732 HA ASN 164 6.038-9.003 1.488 1.00 0.00 ATOM 733 CB ASN 164 7.370-9.470 3.118 1.00 0.00 ATOM 734 1HB ASN 164 7.160-10.496 2.852 1.00 0.00 ATOM 735 2HB ASN 164 6.841-9.223 4.027 1.00 0.00 ATOM 736 QB ASN 164 7.001-9.859 3.440 1.00 0.00 ATOM 737 CG ASN 164 8.861-9.339 3.380 1.00 0.00 ATOM 738 OD1 ASN 164 9.541-10.323 3.639 1.00 0.00 ATOM 739 ND2 ASN 164 9.368-8.114 3.330 1.00 0.00 ATOM 740 1HD2 ASN 164 8.755-7.370 3.149 1.00 0.00 ATOM 741 2HD2 ASN 164 10.333-8.008 3.421 1.00 0.00 ATOM 742 QD2 ASN 164 9.544-7.689 3.285 1.00 0.00 ATOM 743 C ASN 164 6.468-7.206 2.578 1.00 0.00 ATOM 744 O ASN 164 7.317-6.372 2.884 1.00 0.00 ATOM 745 N LEU 165 5.165-6.994 2.737 1.00 0.00 ATOM 746 H LEU 165 4.530-7.693 2.479 1.00 0.00 ATOM 747 CA LEU 165 4.661-5.735 3.294 1.00 0.00 ATOM 748 HA LEU 165 5.168-4.919 2.799 1.00 0.00 ATOM 749 CB LEU 165 3.155-5.596 3.063 1.00 0.00 ATOM 750 1HB LEU 165 2.672-5.465 4.022 1.00 0.00 ATOM 751 2HB LEU 165 2.791-6.508 2.613 1.00 0.00 ATOM 752 QB LEU 165 2.732-5.986 3.318 1.00 0.00 ATOM 753 CG LEU 165 2.747-4.433 2.181 1.00 0.00 ATOM 754 HG LEU 165 3.264-3.540 2.502 1.00 0.00 ATOM 755 QD1 LEU 165 3.224-4.776 0.404 1.00 0. 00 ATOM 756 QD2 LEU 165 0.899-4.125 2.328 1.00 0.00 ATOM 757 CD1 LEU 165 3.133-4.711 0.747 1.00 0.00 ATOM 758 1HD1 LEU 165 3.939-4.053 0.456 1.00 0.00 ATOM 759 2HD1 LEU 165 2.280-4.540 0. 104 1.00 0. 00 ATOM 760 3HD1 LEU 165 3.454-5.737 0.653 1.00 0. 00 ATOM 761 CD2 LEU 165 1.254-4.184 2.300 1.00 0.00 ATOM 762 1HD2 LEU 165 0.714-5.021 1.881 1.00 0.00 ATOM 763 2HD2 LEU 165 0.995-3.284 1.762 1.00 0.00 ATOM 764 3HD2 LEU 165 0.989-4.070 3.341 1.00 0.00 ATOM 765 QQD LEU 165 2.062-4.451 1.366 1.00 0.00 ATOM 766 C LEU 165 4.937-5.636 4.781 1.00 0.00 ATOM 767 O LEU 165 4.596-6.534 5.547 1.00 0.00 ATOM 768 N HIS+ 166 5.540-4.530 5.174 1.00 0.00 ATOM 769 H HIS+ 166 5.776-3.849 4.506 1.00 0.00 ATOM 770 CA HIS+ 166 5.855-4.285 6.565 1.00 0.00 ATOM 771 HA HIS+ 166 5.538-5.145 7.135 1.00 0.00 ATOM 772 CB HIS+ 166 7.369-4.102 6.733 1.00 0.00 ATOM 773 1HB HIS+ 166 7.687-3.254 6.141 1.00 0.00 ATOM 774 2HB HIS+ 166 7.873-4.988 6.380 1.00 0.00

ATOM 775 QB HIS+ 166 7.780-4. 121 6.261 1.00 0.00 ATOM 776 CG HIS+ 166 7.801-3. 860 8.145 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.777-4. 829 9.124 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.257-2.738 8.738 1.00 0.00 ATOM 779 1HD HIS+ 166 7.489-5.760 9.004 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.200-4. 307 10.263 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.499-3.035 10.054 1.00 0.00 ATOM 782 2HD HIS+ 166 8.391-1.772 8.261 1.00 0.00 ATOM 783 1HE HIS+ 166 8.286-4.829 11.204 1.00 0.00 ATOM 784 2HE HIS+ 166 8.625-2.367 10.760 1.00 0.00 ATOM 785 C HIS+ 166 5.099-3.053 7.066 1.00 0.00 ATOM 786 O HIS+ 166 4.465-3.094 8.121 1.00 0.00 ATOM 787 N ASP 167 5.169-1.960 6.305 1.00 0.00 ATOM 788 H ASP 167 5.691-1.988 5.472 1.00 0.00 ATOM 789 CA ASP 167 4.494-0.715 6.692 1.00 0.00 ATOM 790 HA ASP 167 4.000-0.894 7.636 1.00 0.00 ATOM 791 CB ASP 167 5.504 0.425 6.877 1.00 0.00 ATOM 792 1HB ASP 167 5.097 1.143 7.575 1.00 0.00 ATOM 793 2HB ASP 167 5.661 0.910 5.927 1.00 0.00 ATOM 794 QB ASP 167 5.379 1.027 6.751 1.00 0.00 ATOM 795 CG ASP 167 6.847-0.037 7.400 1.00 0.00 ATOM 796 OD1 ASP 167 7.077 0.071 8.621 1.00 0.00 ATOM 797 OD2 ASP 167 7.674-0.505 6.586 1.00 0.00 ATOM 798 C ASP 167 3.446-0.284 5.667 1.00 0.00 ATOM 799 O ASP 167 3.734 0.486 4.754 1.00 0.00 ATOM 800 N TYR 168 2.227-0.775 5.829 1.00 0.00 ATOM 801 H TYR 168 2.057-1.375 6.584 1.00 0.00 ATOM 802 CA TYR 168 1.120-0.429 4.933 1.00 0.00 ATOM 803 HA TYR 168 1.535-0.142 3.969 1.00 0.00 ATOM 804 CB TYR 168 0.194-1.637 4.745 1.00 0.00 ATOM 805 1HB TYR 168 0.602-2.277 3.979 1.00 0.00 ATOM 806 2HB TYR 168-0.780-1.288 4.434 1.00 0.00 ATOM 807 QB TYR 168-0.089-1.782 4.207 1.00 0.00 ATOM 808 QD TYR 168-0.005-2.557 6.150 1.00 0.00 ATOM 809 QE TYR 168-0.292-3.877 8.203 1.00 0.00 ATOM 810 QR TYR 168-0.149-3.217 7.176 1.00 0.00 ATOM 811 CG TYR 168 0.014-2.462 6.003 1.00 0.00 ATOM 812 CD1 TYR 168 0.940-3.435 6.362 1.00 0.00 ATOM 813 1HD TYR 168 1.797-3.607 5.727 1.00 0.00 ATOM 814 CE1 TYR 168 0.782-4.179 7.515 1.00 0.00 ATOM 815 1HE TYR 168 1.514-4.929 7.779 1.00 0.00 ATOM 816 CZ TYR 168-0.310-3.956 8.325 1.00 0.00 ATOM 817 CE2 TYR 168-1.243-2.999 7.990 1.00 0.00 ATOM 818 2HE TYR 168-2.098-2.826 8.626 1.00 0.00 ATOM 819 CD2 TYR 168-1.078-2.259 6.837 1.00 0. 00 ATOM 820 2HD TYR 168-1. 808-1. 508 6.572 1.00 0.00 ATOM 821 OH TYR 168-0.473-4.695 9.471 1.00 0.00 ATOM 822 HH TYR 168 0.132-4.375 10. 147 1.00 0.00 ATOM 823 C TYR 168 0.322 0.749 5.486 1.00 0.00 ATOM 824 O TYR 168 0.229 0.935 6.699 1.00 0.00 ATOM 825 N GLY 169-0.267 1.524 4.593 1.00 0.00 ATOM 826 H GLY 169-0.169 1.317 3.638 1.00 0.00 ATOM 827 CA GLY 169-1.064 2.664 4.993 1.00 0. 00 ATOM 828 1HA GLY 169-0.428 3.536 5.058 1.00 0. 00 ATOM 829 2HA GLY 169-1.500 2.469 5.962 1.00 0.00 ATOM 830 QA GLY 169-0.964 3.003 5.510 1.00 0.00 ATOM 831 C GLY 169-2.160 2.928 3.993 1.00 0.00 ATOM 832 O GLY 169-1.986 2.665 2.811 1.00 0.00 ATOM 833 N MET 170-3.291 3.428 4.450 1.00 0.00 ATOM 834 H MET 170-3.383 3.616 5.406 1.00 0.00 ATOM 835 CA MET 170-4.407 3.708 3.557 1.00 0.00 ATOM 836 HA MET 170-4.092 3.477 2.537 1.00 0.00 ATOM 837 CB MET 170-5.627 2.852 3.928 1.00 0.00 ATOM 838 1HB MET 170-6.520 3.416 3.702 1.00 0.00 ATOM 839 2HB MET 170-5.601 2.659 4.989 1.00 0.00 ATOM 840 QB MET 170-6.060 3.038 4.346 1.00 0.00 ATOM 841 CG MET 170-5.720 1.510 3.208 1.00 0.00 ATOM 842 1HG MET 170-6.168 1.675 2.238 1.00 0.00 ATOM 843 2HG MET 170-6.354 0.855 3.784 1.00 0.00 ATOM 844 QG MET 170-6.261 1.265 3.011 1.00 0.00 ATOM 845 SD MET 170-4.128 0.699 2.972 1.00 0.00 ATOM 846 QE MET 170-4.366-1.078 4.155 1.00 0.00

ATOM 847 CE MET 170-4.326-0.780 3.957 1.00 0.00 ATOM 848 1HE MET 170-4.907-0.551 4.838 1.00 0.00 ATOM 849 2HE MET 170-3.355-1.149 4.251 1.00 0.00 ATOM 850 3HE MET 170-4.836-1.534 3.376 1.00 0.00 ATOM 851 C MET 170-4.777 5.179 3.640 1.00 0.00 ATOM 852 O MET 170-5.083 5.691 4.718 1.00 0.00 ATOM 853 N LEU 171-4.750 5.852 2.505 1.00 0.00 ATOM 854 H LEU 171-4.503 5.385 1.680 1.00 0.00 ATOM 855 CA LEU 171-5.081 7.268 2.453 1.00 0.00 ATOM 856 HA LEU 171-5.261 7.599 3.466 1.00 0.00 ATOM 857 CB LEU 171-3. 909 8.065 1.870 1.00 0.00 ATOM 858 1HB LEU 171-3.075 7.989 2.553 1.00 0.00 ATOM 859 2HB LEU 171-4.204 9.102 1.804 1.00 0.00 ATOM 860 QB LEU 171-3.639 8.546 2.179 1.00 0.00 ATOM 861 CG LEU 171-3. 438 7.609 0.489 1.00 0.00 ATOM 862 HG LEU 171-4.163 6.925 0.076 1.00 0.00 ATOM 863 QD1 LEU 171-3.292 9.072-0.674 1.00 0.00 ATOM 864 QD2 LEU 171-1. 791 6.715 0.609 1.00 0.00 ATOM 865 CD1 LEU 171-3.321 8.791-0.450 1.00 0.00 ATOM 866 1HD1 LEU 171-4. 306 9.151-0.704 1.00 0.00 ATOM 867 2HD1 LEU 171-2.807 8.485-1.349 1.00 0.00 ATOM 868 3HD1 LEU 171-2.762 9.579 0.032 1.00 0.00 ATOM 869 CD2 LEU 171-2.108 6.886 0.586 1.00 0.00 ATOM 870 1HD2 LEU 171-2.228 5.864 0.260 1.00 0.00 ATOM 871 2HD2 LEU 171-1.763 6.899 1.611 1.00 0.00 ATOM 872 3HD2 LEU 171-1.383 7.382-0.043 1.00 0.00 ATOM 873 QQD LEU 171-2.541 7.894-0.032 1.00 0.00 ATOM 874 C LEU 171-6.342 7.492 1.631 1.00 0.00 ATOM 875 O LEU 171-7.039 6.533 1.294 1.00 0.00 ATOM 876 N LEU 172-6.618 8.764 1.316 1.00 0.00 ATOM 877 H LEU 172-6.006 9.464 1.624 1.00 0.00 ATOM 878 CA LEU 172-7.795 9.160 0.529 1.00 0.00 ATOM 879 HA LEU 172-7.967 10.211 0.704 1.00 0.00 ATOM 880 CB LEU 172-7.549 8.945-0.969 1.00 0.00 ATOM 881 1HB LEU 172-8.400 8.416-1.374 1.00 0.00 ATOM 882 2HB LEU 172-6.675 8.322-1.089 1.00 0.00 ATOM 883 QB LEU 172-7.537 8.369-1.231 1.00 0.00 ATOM 884 CG LEU 172-7.353 10.223-1.788 1.00 0.00 ATOM 885 HG LEU 172-8.255 10.815-1.744 1.00 0.00 ATOM 886 QD1 LEU 172-5.947 11.260-1.092 1.00 0.00 ATOM 887 QD2 LEU 172-7.019 9.805-3.588 1.00 0.00 ATOM 888 CD1 LEU 172-6.217 11.060-1.224 1.00 0.00 ATOM 889 1HD1 LEU 172-6.508 11.469-0.269 1. 00 0.00 ATOM 890 2HD1 LEU 172-5.992 11.867-1.907 1.00 0.00 ATOM 891 3HD1 LEU 172-5. 340 10.442-1.100 1.00 0.00 ATOM 892 CD2 LEU 172-7.084 9.884-3.242 1.00 0.00 ATOM 893 1HD2 LEU 172-7.189 8.820-3.391 1.00 0.00 ATOM 894 2HD2 LEU 172-6.078 10.186-3.501 1.00 0.00 ATOM 895 3HD2 LEU 172-7.789 10.408-3.871 1.00 0.00 ATOM 896 QQD LEU 172-6.483 10.532-2.340 1.00 0.00 ATOM 897 C LEU 172-9.041 8.389 0.952 1.00 0.00 ATOM 898 O LEU 172-9.509 7.520 0.220 1.00 0.00 ATOM 899 N PRO 173-9.595 8.687 2.139 1.00 0.00 ATOM 900 CD PRO 173-9.109 9.708 3.087 1.00 0.00 ATOM 901 CA PRO 173-10.788 8. 000 2.636 1.00 0.00 ATOM 902 HA PRO 173-10.572 6.966 2.879 1.00 0.00 ATOM 903 CB PRO 173-11.150 8.769 3.908 1.00 0.00 ATOM 904 1HB PRO 173-11.525 8.082 4.653 1.00 0.00 ATOM 905 2HB PRO 173-11.904 9.509 3.681 1.00 0.00 ATOM 906 QB PRO 173-11.714 8.796 4.167 1.00 0.00 ATOM 907 CG PRO 173-9.874 9.404 4.346 1.00 0.00 ATOM 908 1HG PRO 173-9.317 8. 718 4.967 1.00 0.00 ATOM 909 2HG PRO 173-10.085 10.315 4.887 1.00 0.00 ATOM 910 QG PRO 173-9.701 9.517 4.927 1.00 0.00 ATOM 911 1HD PRO 173-8.047 9.601 3.255 1.00 0.00 ATOM 912 2HD PRO 173-9.339 10.703 2.736 1.00 0.00 ATOM 913 QD PRO 173-8.693 10.152 2.996 1.00 0.00 ATOM 914 C PRO 173-11.936 8.046 1.635 1.00 0.00 ATOM 915 O PRO 173-12.104 9.020 0.895 1.00 0.00 ATOM 916 N CYS 174-12.714 6.986 1. 607 1.00 0.00 ATOM 917 H CYS 174-12.527 6.238 2.218 1.00 0.00 ATOM 918 CA CYS 174-13.839 6.893 0.698 1.00 0.00

ATOM 919 HA CYS 174-13.864 7.796 0. 106 1.00 0.00 ATOM 920 CB CYS 174-13.663 5.692-0.227 1.00 0.00 ATOM 921 1HB CYS 174-13.404 4.827 0.367 1.00 0.00 ATOM 922 2HB CYS 174-12.861 5.897-0.920 1.00 0.00 ATOM 923 QB CYS 174-13.132 5.362-0.276 1.00 0.00 ATOM 924 SG CYS 174-15.137 5.271-1.202 1.00 0.00 ATOM 925 C CYS 174-15.136 6.786 1.483 1.00 0.00 ATOM 926 O CYS 174-16.136 7.412 1.140 1.00 0.00 ATOM 927 N GLY 175-15.100 6.005 2.551 1.00 0.00 ATOM 928 H GLY 175-14. 263 5.545 2.784 1.00 0.00 ATOM 929 CA GLY 175-16. 263 5.841 3.394 1.00 0.00 ATOM 930 1HA GLY 175-16.753 4.913 3.145 1.00 0.00 ATOM 931 2HA GLY 175-16.944 6.662 3.217 1.00 0.00 ATOM 932 QA GLY 175-16.848 5.788 3.181 1.00 0.00 ATOM 933 C GLY 175-15.875 5.822 4.852 1.00 0.00 ATOM 934 O GLY 175-14.840 6.370 5.223 1.00 0.00 ATOM 935 N ILE 176-16.687 5.180 5.679 1.00 0.00 ATOM 936 H ILE 176-17.492 4.749 5.326 1.00 0. 00 ATOM 937 CA ILE 176-16.394 5.085 7.101 1.00 0.00 ATOM 938 HA ILE 176-16.019 6.046 7.426 1.00 0.00 ATOM 939 CB ILE 176-17.673 4.756 7.915 1.00 0.00 ATOM 940 HB ILE 176-18.367 5.572 7.783 1.00 0.00 ATOM 941 QG2 ILE 176-18.500 3.191 7.274 1.00 0.00 ATOM 942 CG2 ILE 176-18.342 3.490 7.395 1.00 0.00 ATOM 943 1HG2 ILE 176-17.586 2.796 7.056 1.00 0. 00 ATOM 944 2HG2 ILE 176-18.998 3.739 6.575 1.00 0.00 ATOM 945 3HG2 ILE 176-18.915 3.037 8.190 1.00 0.00 ATOM 946 CG1 ILE 176-17.356 4.618 9.406 1.00 0.00 ATOM 947 1HG1 ILE 176-16.807 5.488 9.734 1.00 0.00 ATOM 948 2HG1 ILE 176-16.750 3.737 9.559 1.00 0.00 ATOM 949 QG1 ILE 176-16. 778 4.613 9.647 1.00 0.00 ATOM 950 QD1 ILE 176-18.881 4.457 10.481 1.00 0. 00 ATOM 951 CD1 ILE 176-18.588 4.488 10.275 1.00 0.00 ATOM 952 1HD1 ILE 176-19.101 5.437 10.317 1.00 0.00 ATOM 953 2HD1 ILE 176-18.296 4.191 11.271 1.00 0.00 ATOM 954 3HD1 ILE 176-19.246 3.741 9.855 1.00 0.00 ATOM 955 C ILE 176-15.312 4.027 7.341 1.00 0.00 ATOM 956 O ILE 176-14.530 4.119 8.287 1.00 0.00 ATOM 957 N ASP 177-15.277 3.027 6.463 1.00 0. 00 ATOM 958 H ASP 177-15.926 3.015 5.732 1.00 0.00 ATOM 959 CA ASP 177-14.302 1.945 6.558 1.00 0. 00 ATOM 960 HA ASP 177-13.597 2.195 7.336 1.00 0.00 ATOM 961 CB ASP 177-15.011 0.632 6.921 1.00 0.00 ATOM 962 1HB ASP 177-15.776 0.836 7.656 1.00 0.00 ATOM 963 2HB ASP 177-14.289-0.052 7.341 1.00 0.00 ATOM 964 QB ASP 177-15.032 0.392 7.499 1.00 0. 00 ATOM 965 CG ASP 177-15.661-0.038 5.722 1.00 0.00 ATOM 966 OD1 ASP 177-16.454 0.625 5.019 1.00 0.00 ATOM 967 OD2 ASP 177-15. 372-1.225 5.472 1.00 0.00 ATOM 968 C ASP 177-13.551 1.762 5.239 1.00 0.00 ATOM 969 0 ASP 177-12.636 0.940 5.140 1.00 0.00 ATOM 970 N LYS+ 178-13.965 2.502 4.219 1.00 0.00 ATOM 971 H LYS+ 178-14.711 3.119 4.352 1.00 0.00 ATOM 972 CA LYS+ 178-13. 358 2.386 2.899 1.00 0.00 ATOM 973 HA LYS+ 178-12.781 1.473 2.886 1.00 0.00 ATOM 974 CB LYS+ 178-14.455 2.283 1.841 1.00 0.00 ATOM 975 1HB LYS+ 178-14.000 2.078 0.885 1.00 0.00 ATOM 976 2HB LYS+ 178-14.978 3.227 1.788 1.00 0.00 ATOM 977 QB LYS+ 178-14.489 2.653 1.337 1.00 0.00 ATOM 978 CG LYS+ 178-15.471 1.187 2.137 1.00 0.00 ATOM 979 1HG LYS+ 178-16.380 1.643 2.503 1.00 0.00 ATOM 980 2HG LYS+ 178-15.065 0.535 2.898 1.00 0.00 ATOM 981 QG LYS+ 178-15.722 1.089 2.701 1.00 0.00 ATOM 982 CD LYS+ 178-15.795 0.357 0.903 1.00 0.00 ATOM 983 1HD LYS+ 178-15.005 0.489 0.176 1.00 0.00 ATOM 984 2HD LYS+ 178-16.729 0.703 0.484 1.00 0.00 ATOM 985 QD LYS+ 178-15.867 0.596 0.330 1.00 0. 00 ATOM 986 CE LYS+ 178-15.924-1.129 1.225 1.00 0.00 ATOM 987 1HE LYS+ 178-15.089-1.653 0.775 1.00 0.00 ATOM 988 2HE LYS+ 178-16.844-1.497 0.797 1.00 0.00 ATOM 989 QE LYS+ 178-15.966-1.575 0.786 1.00 0. 00 ATOM 990 NZ LYS+ 178-15.932-1.402 2.692 1.00 0.00

ATOM 991 1HZ LYS+ 178-16.644-2.122 2.918 1.00 0.00 ATOM 992 2HZ LYS+ 178-16.151-0.537 3.232 1.00 0.00 ATOM 993 3HZ LYS+ 178-14.997-1.757 2.996 1.00 0.00 ATOM 994 QZ LYS+ 178-15.931-1.472 3.049 1.00 0.00 ATOM 995 C LYS+ 178-12.413 3.535 2.583 1.00 0.00 ATOM 996 O LYS+ 178-12.569 4.647 3.084 1.00 0.00 ATOM 997 N PHE 179-11.426 3.243 1.739 1.00 0.00 ATOM 998 H PHE 179-11.368 2.335 1.372 1.00 0.00 ATOM 999 CA PHE 179-10. 426 4.217 1.336 1.00 0.00 ATOM 1000 HA PHE 179-10.777 5.202 1.600 1.00 0.00 ATOM 1001 CB PHE 179-9.097 3.944 2.042 1.00 0.00 ATOM 1002 1HB PHE 179-8.392 4.680 1.725 1.00 0.00 ATOM 1003 2HB PHE 179-8. 730 2.975 1.744 1.00 0.00 ATOM 1004 QB PHE 179-8.561 3.828 1.735 1.00 0.00 ATOM 1005 QD PHE 179-9.172 3.979 3.711 1.00 0.00 ATOM 1006 QE PHE 179-9.283 4.032 6.167 1.00 0.00 ATOM 1007 QR PHE 179-9.250 4.016 5.431 1.00 0.00 ATOM 1008 CG PHE 179-9.165 3.975 3.544 1.00 0.00 ATOM 1009 CD1 PHE 179-8. 810 5.118 4.241 1.00 0.00 ATOM 1010 1HD PHE 179-8.484 5.992 3.696 1.00 0.00 ATOM 1011 CE1 PHE 179-8. 871 5.151 5.621 1.00 0.00 ATOM 1012 1HE PHE 179-8.591 6.048 6.153 1.00 0.00 ATOM 1013 CZ PHE 179-9.289 4.035 6.320 1.00 0.00 ATOM 1014 HZ PHE 179-9.338 4.060 7.399 1.00 0.00 ATOM 1015 CE2 PHE 179-9.645 2.889 5.637 1.00 0.00 ATOM 1016 2HE PHE 179-9.975 2.016 6.180 1.00 0.00 ATOM 1017 CD2 PHE 179-9.582 2.862 4.258 1.00 0.00 ATOM 1018 2HD PHE 179-9.861 1.965 3.725 1.00 0.00 ATOM 1019 C PHE 179-10.187 4.146-0.160 1.00 0.00 ATOM 1020 O PHE 179-10.881 3.424-0.877 1.00 0.00 ATOM 1021 N ARG+ 180-9.180 4.880-0.611 1.00 0.00 ATOM 1022 H ARG+ 180-8.663 5.417 0.030 1.00 0.00 ATOM 1023 CA ARG+ 180-8.796 4.901-2.018 1.00 0.00 ATOM 1024 HA ARG+ 180-9.197 4.017-2.494 1.00 0.00 ATOM 1025 CB ARG+ 180-9.346 6.145-2.728 1.00 0.00 ATOM 1026 1HB ARG+ 180-9.053 6.100-3.766 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.903 7.021-2.288 1.00 0.00 ATOM 1028 QB ARG+ 180-8.978 6.561-3.027 1.00 0.00 ATOM 1029 CG ARG+ 180-10.856 6.290-2.666 1.00 0.00 ATOM 1030 1HG ARG+ 180-11.227 5.723-1.824 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.282 5.902-3.580 1.00 0.00 ATOM 1032 QG ARG+ 180-11.254 5.813-2.702 1.00 0.00 ATOM 1033 CD ARG+ 180-11.264 7.746-2.505 1.00 0.00 ATOM 1034 1HD ARG+ 180-10. 455 8.373-2.854 1.00 0.00 ATOM 1035 2HD ARG+ 180-11.440 7.942-1.459 1.00 0.00 ATOM 1036 QD ARG+ 180-10.947 8.158-2.156 1.00 0.00 ATOM 1037 NE ARG+ 180-12.473 8.066-3.262 1.00 0.00 ATOM 1038 HE ARG+ 180-12.568 7.659-4.154 1.00 0.00 ATOM 1039 CZ ARG+ 180-13.436 8.874-2.818 1.00 0.00 ATOM 1040 NH1 ARG+ 180-13.331 9.444-1.620 1.00 0.00 ATOM 1041 IHH1 ARG+ 180-12.525 9.268-1.046 1. 00 0.00 ATOM 1042 2HH1 ARG+ 180-14.053 10.050-1.284 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.289 9.659-1.165 1.00 0.00 ATOM 1044 NH2 ARG+ 180-14.502 9.115-3.574 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-14.582 8.690-4.479 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-15.228 9.719-3.244 1.00 0.00 ATOM 1047 QH2 ARG+ 180-14.905 9.205-3.861 1.00 0.00 ATOM 1048 C ARG+ 180-7.274 4.892-2.156 1.00 0.00 ATOM 1049 O ARG+ 180-6.742 4.582-3.210 1.00 0.00 ATOM 1050 N GLY 181-6.571 5.255-1.096 1.00 0.00 ATOM 1051 H GLY 181-7.030 5.505-0.265 1.00 0.00 ATOM 1052 CA GLY 181-5.125 5.301-1.170 1.00 0.00 ATOM 1053 1HA GLY 181-4.789 6.247-0.773 1.00 0.00 ATOM 1054 2HA GLY 181-4.833 5.239-2.208 1.00 0.00 ATOM 1055 QA GLY 181-4.811 5.743-1.490 1.00 0.00 ATOM 1056 C GLY 181-4.442 4.187-0.413 1.00 0.00 ATOM 1057 0 GLY 181-4.997 3.637 0.536 1.00 0.00 ATOM 1058 N VAL 182-3.225 3.869-0.841 1.00 0.00 ATOM 1059 H VAL 182-2.851 4.365-1.596 1.00 0.00 ATOM 1060 CA VAL 182-2.417 2.821-0.223 1.00 0.00 ATOM 1061 HA VAL 182-2.729 2.717 0.809 1.00 0.00 ATOM 1062 CB VAL 182-2.583 1.450-0.931 1.00 0.00

ATOM 1063 HB VAL 182-1.801 1.364-1.673 1.00 0.00 ATOM 1064 QG1 VAL 182-2.370 0.043 0.295 1.00 0.00 ATOM 1065 QG2 VAL 182-4.241 1.303-1.812 1.00 0.00 ATOM 1066 CG1 VAL 182-2.411 0.313 0.060 1.00 0.00 ATOM 1067 1HG1 VAL 182-1.403-0.070-0. 004 1.00 0.00 ATOM 1068 2HG1 VAL 182-3.111-0.476-0. 173 1.00 0.00 ATOM 1069 3HG1 VAL 182-2. 596 0.675 1.061 1.00 0.00 ATOM 1070 CG2 VAL 182-3.924 1.331-1.644 1.00 0.00 ATOM 1071 1HG2 VAL 182-4. 160 0.288-1.796 1. 00 0. 00 ATOM 1072 2HG2 VAL 182-3.870 1.831-2.600 1.00 0.00 ATOM 1073 3HG2 VAL 182-4. 694 1.790-1.041 1.00 0.00 ATOM 1074 QQG VAL 182-3.306 0.673-0.759 1.00 0.00 ATOM 1075 C VAL 182-0.930 3.190-0.262 1.00 0.00 ATOM 1076 O VAL 182-0.380 3.460-1.329 1.00 0.00 ATOM 1077 N GLU 183-0.289 3.179 0.900 1.00 0.00 ATOM 1078 H GLU 183-0.791 2.943 1.715 1.00 0.00 ATOM 1079 CA GLU 183 1.137 3.482 1.016 1.00 0.00 ATOM 1080 HA GLU 183 1.558 3.501 0.020 1.00 0.00 ATOM 1081 CB GLU 183 1.354 4.843 1.685 1.00 0.00 ATOM 1082 1HB GLU 183 1.404 5.603 0.920 1.00 0.00 ATOM 1083 2HB GLU 183 2.294 4.822 2.217 1.00 0.00 ATOM 1084 QB GLU 183 1.849 5.213 1.569 1.00 0.00 ATOM 1085 CG GLU 183 0.265 5.234 2.671 1.00 0.00 ATOM 1086 1HG GLU 183 0.345 4.605 3.545 1.00 0.00 ATOM 1087 2HG GLU 183-0.697 5.086 2.206 1.00 0.00 ATOM 1088 QG GLU 183-0.176 4.846 2.876 1.00 0.00 ATOM 1089 CD GLU 183 0.375 6.678 3.103 1.00 0.00 ATOM 1090 OE1 GLU 183-0.628 7.227 3.599 1.00 0.00 ATOM 1091 OE2 GLU 183 1.465 7.263 2.932 1.00 0.00 ATOM 1092 C GLU 183 1.819 2.381 1.825 1.00 0.00 ATOM 1093 O GLU 183 1.775 2.379 3.049 1.00 0.00 ATOM 1094 N PHE 184 2.399 1.413 1.138 1.00 0.00 ATOM 1095 H PHE 184 2.370 1.439 0.164 1.00 0.00 ATOM 1096 CA PHE 184 3.022 0.273 1.805 1.00 0.00 ATOM 1097 HA PHE 184 2.884 0.401 2.865 1.00 0.00 ATOM 1098 CB PHE 184 2.333-1.026 1.374 1.00 0.00 ATOM 1099 1HB PHE 184 1.422-1.156 1.940 1.00 0.00 ATOM 1100 2HB PHE 184 2.994-1.853 1.589 1.00 0.00 ATOM 1101 QB PHE 184 2.208-1.504 1.765 1.00 0.00 ATOM 1102 QD PHE 184 1.951-1.095-0.269 1.00 0.00 ATOM 1103 QE PHE 184 1.388-1.243-2.656 1.00 0.00 ATOM 1104 QR PHE 184 1.556-1.201-1.940 1.00 0.00 ATOM 1105 CG PHE 184 1.991-1.089-0.099 1.00 0.00 ATOM 1106 CD1 PHE 184 2.656-1.971-0.933 1.00 0.00 ATOM 1107 1HD PHE 184 3.431-2.602-0.525 1.00 0.00 ATOM 1108 CE1 PHE 184 2.339-2.058-2.274 1.00 0.00 ATOM 1109 1HE PHE 184 2.869-2.752-2.910 1. 00 0.00 ATOM 1110 CZ PHE 184 1.352-1.256-2.804 1.00 0.00 ATOM 1111 HZ PHE 184 1.101-1.329-3.851 1.00 0.00 ATOM 1112 CE2 PHE 184 0.681-0.366-1.991 1.00 0.00 ATOM 1113 2HE PHE 184-0.093 0.265-2.402 1.00 0.00 ATOM 1114 CD2 PHE 184 0.997-0.287-0.647 1.00 0.00 ATOM 1115 2HD PHE 184 0.470 0.411-0.013 1.00 0.00 ATOM 1116 C PHE 184 4.510 0.139 1.517 1.00 0.00 ATOM 1117 O PHE 184 4.969 0.407 0.414 1.00 0.00 ATOM 1118 N VAL 185 5.250-0.327 2.514 1.00 0.00 ATOM 1119 H VAL 185 4.817-0.550 3.365 1.00 0.00 ATOM 1120 CA VAL 185 6.678-0.551 2.372 1.00 0.00 ATOM 1121 HA VAL 185 6.979-0.186 1.400 1.00 0.00 ATOM 1122 CB VAL 185 7. 500 0.189 3.453 1.00 0.00 ATOM 1123 HB VAL 185 7.597-0.461 4.315 1.00 0.00 ATOM 1124 QG1 VAL 185 9.223 0.590 2.824 1.00 0.00 ATOM 1125 QG2 VAL 185 6.634 1.764 4.006 1.00 0.00 ATOM 1126 CG1 VAL 185 8.894 0.512 2.943 1.00 0.00 ATOM 1127 1HG1 VAL 185 8.980 1.578 2.790 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.064-0.002 2.009 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.624 0.193 3.672 1.00 0.00 ATOM 1130 CG2 VAL 185 6.800 1.462 3.899 1.00 0.00 ATOM 1131 1HG2 VAL 185 7.077 1.685 4.920 1.00 0.00 ATOM 1132 2HG2 VAL 185 5.729 1.326 3.839 1.00 0.00 ATOM 1133 3HG2 VAL 185 7.095 2.281 3.259 1.00 0.00 ATOM 1134 QQG VAL 185 7.928 1.177 3.415 1.00 0.00

ATOM 1135 C VAL 185 6.977-2.047 2.454 1.00 0.00 ATOM 1136 O VAL 185 6.790-2.670 3.496 1.00 0.00 ATOM 1137 N CYS 186 7. 432-2.624 1.352 1.00 0.00 ATOM 1138 H CYS 186 7.559-2. 082 0.541 1.00 0.00 ATOM 1139 CA CYS 186 7.751-4.044 1.319 1.00 0.00 ATOM 1140 HA CYS 186 7.491-4.457 2.285 1.00 0.00 ATOM 1141 CB CYS 186 6.939-4.767 0.237 1.00 0.00 ATOM 1142 1HB CYS 186 5.936-4.929 0.604 1.00 0.00 ATOM 1143 2HB CYS 186 7.397-5.722 0.036 1.00 0.00 ATOM 1144 QB CYS 186 6.667-5.325 0.320 1.00 0.00 ATOM 1145 SG CYS 186 6.810-3.886-1.349 1.00 0.00 ATOM 1146 C CYS 186 9.243-4.245 1.092 1.00 0.00 ATOM 1147 O CYS 186 9.813-3.688 0. 166 1.00 0.00 ATOM 1148 N CYS 187 9.882-5.025 1.947 1.00 0.00 ATOM 1149 H CYS 187 9.387-5.442 2.683 1.00 0. 00 ATOM 1150 CA CYS 187 11.319-5.258 1.828 1.00 0.00 ATOM 1151 HA CYS 187 11.746-4.412 1.315 1.00 0.00 ATOM 1152 CB CYS 187 11.947-5.367 3.218 1.00 0.00 ATOM 1153 1HB CYS 187 13.004-5.155 3.146 1.00 0.00 ATOM 1154 2HB CYS 187 11.811-6.372 3.590 1.00 0.00 ATOM 1155 QB CYS 187 12.408-5.763 3.368 1.00 0.00 ATOM 1156 SG CYS 187 11.228-4.218 4.437 1.00 0.00 ATOM 1157 C CYS 187 11.606-6.513 1.021 1.00 0.00 ATOM 1158 O CYS 187 10.810-7.447 1.028 1.00 0.00 ATOM 1159 N PRO 188 12.740-6.538 0.297 1.00 0.00 ATOM 1160 CD PRO 188 13.731-5.445 0.215 1.00 0.00 ATOM 1161 CA PRO 188 13.120-7.685-0.535 1.00 0.00 ATOM 1162 HA PRO 188 12.359-7.904-1.270 1.00 0.00 ATOM 1163 CB PRO 188 14.395-7.220-1.248 1.00 0.00 ATOM 1164 1HB PRO 188 14.151-6.888-2.246 1.00 0.00 ATOM 1165 2HB PRO 188 15.097-8.040-1.299 1.00 0.00 ATOM 1166 QB PRO 188 14.624-7.464-1.772 1.00 0.00 ATOM 1167 CG PRO 188 14.925-6.101-0.417 1.00 0.00 ATOM 1168 1HG PRO 188 15.453-5.397-1.043 1.00 0.00 ATOM 1169 2HG PRO 188 15.585-6.493 0.345 1.00 0.00 ATOM 1170 QG PRO 188 15.519-5.945-0.349 1.00 0.00 ATOM 1171 1HD PRO 188 13.368-4.641-0.409 1.00 0.00 ATOM 1172 2HD PRO 188 13.982-5.076 1.199 1.00 0.00 ATOM 1173 QD PRO 188 13.675-4.858 0.395 1.00 0.00 ATOM 1174 C PRO 188 13.397-8.946 0.281 1.00 0.00 ATOM 1175 O PRO 188 14.189-8.927 1.227 1.00 0.00 ATOM 1176 N LEU 189 12.739-10.030-0. 106 1.00 0.00 ATOM 1177 H LEU 189 12.128-9.965-0.872 1.00 0.00 ATOM 1178 CA LEU 189 12.894-11.318 0.550 1.00 0.00 ATOM 1179 HA LEU 189 13.764-11.266 1.188 1.00 0.00 ATOM 1180 CB LEU 189 11.662-11.640 1.398 1.00 0.00 ATOM 1181 1HB LEU 189 10.861-11.921 0.732 1.00 0.00 ATOM 1182 2HB LEU 189 11.371-10.746 1.928 1.00 0.00 ATOM 1183 QB LEU 189 11.116-11.333 1.330 1.00 0.00 ATOM 1184 CG LEU 189 11.852-12.765 2.417 1.00 0.00 ATOM 1185 HG LEU 189 12.557-13.483 2.020 1.00 0.00 ATOM 1186 QD1 LEU 189 12.550-12.090 4.025 1.00 0.00 ATOM 1187 QD2 LEU 189 10.226-13.652 2.727 1.00 0.00 ATOM 1188 CD1 LEU 189 12.417-12.220 3.718 1.00 0.00 ATOM 1189 1HD1 LEU 189 12.637-13.039 4.385 1.00 0.00 ATOM 1190 2HD1 LEU 189 11.691-11.565 4.177 1.00 0. 00 ATOM 1191 3HD1 LEU 189 13.322-11.668 3.513 1.00 0.00 ATOM 1192 CD2 LEU 189 10.536-13.483 2.668 1.00 0.00 ATOM 1193 1HD2 LEU 189 10.694-14.285 3.373 1.00 0.00 ATOM 1194 2HD2 LEU 189 10.166-13.888 1.738 1.00 0.00 ATOM 1195 3HD2 LEU 189 9.818-12.785 3.069 1.00 0.00 ATOM 1196 QQD LEU 189 11.388-12.871 3.376 1.00 0.00 ATOM 1197 C LEU 189 13.105-12.410-0.495 1.00 0.00 ATOM 1198 OT1 LEU 189 12.672-12.208-1.651 1.00 0.00 ATOM 1199 OT2 LEU 189 13.700-13.452-0.154 1.00 0.00 TER ENDMDL MODEL 8 ATOM 1 N SER 124 14.878 16.046-0.049 1.00 0.00 ATOM 2 CA SER 124 15.756 14. 966 0.471 1.00 0.00 ATOM 3 HA SER 124 16.443 14.666-0.305 1.00 0.00 ATOM 4 CB SER 124 16.532 15.526 1.660 1.00 0.00

ATOM 5 1HB SER 124 17.561 15.200 1.603 1.00 0.00 ATOM 6 2HB SER 124 16.088 15.166 2.578 1.00 0.00 ATOM 7 QB SER 124 16.825 15.183 2.090 1.00 0.00 ATOM 8 OG SER 124 16.496 16.947 1.655 1.00 0.00 ATOM 9 HG SER 124 16.493 17.273 2.563 1.00 0.00 ATOM 10 C SER 124 14.916 13.775 0.893 1.00 0.00 ATOM 11 O SER 124 15.338 12.938 1.690 1.00 0.00 ATOM 12 1HT SER 124 15.337 16.970 0.082 1.00 0.00 ATOM 13 2HT SER 124 13.969 16.047 0.468 1.00 0.00 ATOM 14 3HT SER 124 14.686 15.899-1.058 1.00 0.00 ATOM 15 N ASP 125 13.714 13.741 0.356 1.00 0.00 ATOM 16 H ASP 125 13.449 14.459-0.256 1.00 0.00 ATOM 17 CA ASP 125 12.745 12.708 0.645 1.00 0.00 ATOM 18 HA ASP 125 13.059 12.182 1.533 1.00 0.00 ATOM 19 CB ASP 125 11.380 13.361 0.893 1.00 0.00 ATOM 20 1HB ASP 125 10.956 12.963 1.803 1.00 0.00 ATOM 21 2HB ASP 125 10.723 13.136 0.066 1.00 0.00 ATOM 22 QB ASP 125 10.840 13.050 0.934 1.00 0.00 ATOM 23 CG ASP 125 11.478 14.875 1.030 1.00 0.00 ATOM 24 OD1 ASP 125 11.869 15.546 0.043 1.00 0.00 ATOM 25 OD2 ASP 125 11.194 15.388 2.127 1.00 0.00 ATOM 26 C ASP 125 12.658 11.733-0.519 1.00 0.00 ATOM 27 O ASP 125 13.306 11.927-1.549 1.00 0.00 ATOM 28 N ALA 126 11.853 10.695-0.358 1.00 0.00 ATOM 29 H ALA 126 11.355 10.601 0.482 1.00 0.00 ATOM 30 CA ALA 126 11.679 9.698-1.403 1.00 0.00 ATOM 31 HA ALA 126 12.028 10.125-2.332 1.00 0.00 ATOM 32 QB ALA 126 12.707 8.165-1.033 1.00 0.00 ATOM 33 CB ALA 126 12.510 8.458-1.104 1.00 0.00 ATOM 34 1HB ALA 126 11.875 7.692-0.683 1.00 0.00 ATOM 35 2HB ALA 126 13.289 8.708-0.399 1.00 0.00 ATOM 36 3HB ALA 126 12.956 8.094-2.018 1.00 0.00 ATOM 37 C ALA 126 10.213 9.325-1.545 1.00 0.00 ATOM 38 O ALA 126 9.498 9.203-0.553 1.00 0.00 ATOM 39 N LEU 127 9.771 9.139-2.781 1.00 0.00 ATOM 40 H LEU 127 10.388 9.247-3.531 1.00 0.00 ATOM 41 CA LEU 127 8.387 8.775-3.045 1.00 0.00 ATOM 42 HA LEU 127 7.793 9.108-2.209 1.00 0.00 ATOM 43 CB LEU 127 7.891 9.467-4.325 1.00 0.00 ATOM 44 1HB LEU 127 8.099 8.813-5.160 1.00 0.00 ATOM 45 2HB LEU 127 8.458 10.377-4.456 1.00 0.00 ATOM 46 QB LEU 127 8.279 9.595-4.808 1.00 0.00 ATOM 47 CG LEU 127 6.396 9.827-4.364 1.00 0.00 ATOM 48 HG LEU 127 6.279 10.781-4.857 1.00 0.00 ATOM 49 QD1 LEU 127 5.426 8.553-5.350 1.00 0.00 ATOM 50 QD2 LEU 127 5.692 9.986-2.625 1.00 0.00 ATOM 51 CD1 LEU 127 5.612 8.797-5.162 1.00 0.00 ATOM 52 1HD1 LEU 127 4.554 8.934-4.985 1.00 0.00 ATOM 53 2HD1 LEU 127 5.902 7.803-4.851 1.00 0.00 ATOM 54 3HD1 LEU 127 5.820 8.922-6.215 1.00 0. 00 ATOM 55 CD2 LEU 127 5.826 9.955-2.957 1.00 0.00 ATOM 56 1HD2 LEU 127 6.468 10.591-2.365 1.00 0.00 ATOM 57 2HD2 LEU 127 5.768 8.978-2.502 1.00 0.00 ATOM 58 3HD2 LEU 127 4.838 10.388-3.008 1.00 0.00 ATOM 59 QQD LEU 127 5.559 9.270-3.988 1.00 0.00 ATOM 60 C LEU 127 8.255 7.260-3.174 1.00 0. 00 ATOM 61 O LEU 127 7.158 6.730-3.343 1.00 0.00 ATOM 62 N LEU 128 9.381 6.564-3.095 1.00 0.00 ATOM 63 H LEU 128 10.226 7.032-2.958 1.00 0.00 ATOM 64 CA LEU 128 9.381 5.118-3.208 1.00 0.00 ATOM 65 HA LEU 128 8.391 4.764-2.986 1.00 0.00 ATOM 66 CB LEU 128 9.745 4.712-4.641 1.00 0. 00 ATOM 67 1HB LEU 128 10.812 4.556-4.686 1.00 0.00 ATOM 68 2HB LEU 128 9.490 5.532-5.297 1.00 0.00 ATOM 69 QB LEU 128 10.151 5.044-4.992 1.00 0.00 ATOM 70 CG LEU 128 9.050 3.448-5.158 1.00 0.00 ATOM 71 HG LEU 128 8.651 2.891-4.322 1.00 0.00 ATOM 72 QD1 LEU 128 7.613 3.910-6.277 1.00 0.00 ATOM 73 QD2 LEU 128 10.264 2.349-6.081 1.00 0.00 ATOM 74 CD1 LEU 128 7.888 3.821-6.063 1.00 0.00 ATOM 75 1HD1 LEU 128 7.241 2.965-6.190 1.00 0.00 ATOM 76 2HD1 LEU 128 8.267 4.132-7.026 1.00 0.00

ATOM 77 3HD1 LEU 128 7.330 4.631-5.616 1.00 0.00 ATOM 78 CD2 LEU 128 10.031 2.559-5.903 1.00 0.00 ATOM 79 1HD2 LEU 128 9.569 2.194-6.808 1.00 0.00 ATOM 80 2HD2 LEU 128 10.309 1.724-5.278 1.00 0.00 ATOM 81 3HD2 LEU 128 10.913 3.129-6.156 1.00 0.00 ATOM 82 QQD LEU 128 8.938 3.129-6.179 1.00 0.00 ATOM 83 C LEU 128 10.348 4.514-2.193 1.00 0.00 ATOM 84 O LEU 128 10.409 4.965-1.052 1.00 0.00 ATOM 85 N VAL 129 11.080 3.493-2.621 1.00 0.00 ATOM 86 H VAL 129 10.954 3.196-3.543 1.00 0.00 ATOM 87 CA VAL 129 12.054 2.787-1.774 1.00 0.00 ATOM 88 HA VAL 129 11.508 2.200-1.053 1.00 0.00 ATOM 89 CB VAL 129 12.926 1.828-2.618 1.00 0.00 ATOM 90 HB VAL 129 13.589 2.428-3.227 1.00 0.00 ATOM 91 QG1 VAL 129 13.988 0.728-1.524 1.00 0.00 ATOM 92 QG2 VAL 129 11.868 0.784-3.763 1.00 0.00 ATOM 93 CG1 VAL 129 13.784 0.938-1.733 1.00 0.00 ATOM 94 1HG1 VAL 129 14.654 1.489-1.406 1.00 0.00 ATOM 95 2HG1 VAL 129 14.097 0.069-2.293 1.00 0.00 ATOM 96 3HG1 VAL 129 13.211 0. 625-0.872 1.00 0.00 ATOM 97 CG2 VAL 129 12.069 0.984-3.543 1.00 0.00 ATOM 98 1HG2 VAL 129 11.029 1.231-3.397 1.00 0.00 ATOM 99 2HG2 VAL 129 12.227-0.062-3.323 1.00 0.00 ATOM 100 3HG2 VAL 129 12.346 1.181-4.568 1.00 0.00 ATOM 101 QQG VAL 129 12.928 0.756-2.643 1.00 0.00 ATOM 102 C VAL 129 12.993 3.743-1.028 1.00 0.00 ATOM 103 O VAL 129 13.847 4.381-1.641 1.00 0.00 ATOM 104 N PRO 130 12.851 3.843 0.310 1.00 0.00 ATOM 105 CD PRO 130 11.871 3.136 1.133 1.00 0.00 ATOM 106 CA PRO 130 13.691 4.699 1.137 1.00 0.00 ATOM 107 HA PRO 130 13.919 5.623 0.647 1.00 0.00 ATOM 108 CB PRO 130 12.822 4.971 2.379 1.00 0.00 ATOM 109 1HB PRO 130 12.575 6.022 2.417 1.00 0.00 ATOM 110 2HB PRO 130 13.373 4.700 3.267 1.00 0.00 ATOM 111 QB PRO 130 12.974 5.361 2.842 1.00 0.00 ATOM 112 CG PRO 130 11.587 4.129 2.226 1.00 0.00 ATOM 113 1HG PRO 130 10.751 4.757 1.951 1.00 0.00 ATOM 114 2HG PRO 130 11.379 3.614 3.152 1.00 0.00 ATOM 115 QG PRO 130 11.065 4.186 2.551 1.00 0.00 ATOM 116 1HD PRO 130 10.975 2.921 0.572 1.00 0.00 ATOM 117 2HD PRO 130 12.291 2.228 1.542 1.00 0.00 ATOM 118 QD PRO 130 11.633 2.575 1.057 1.00 0.00 ATOM 119 C PRO 130 14.996 4.010 1.532 1.00 0.00 ATOM 120 O PRO 130 16.013 4.133 0.853 1.00 0.00 ATOM 121 N ASP 131 14.946 3.292 2.643 1.00 0.00 ATOM 122 H ASP 131 14.103 3.251 3.126 1.00 0.00 ATOM 123 CA ASP 131 16.109 2.575 3.162 1.00 0.00 ATOM 124 HA ASP 131 16.986 3.156 2.916 1. 00 0. 00 ATOM 125 CB ASP 131 16.016 2.447 4. 689 1. 00 0.00 ATOM 126 1HB ASP 131 15.092 1.954 4.948 1.00 0.00 ATOM 127 2HB ASP 131 16.029 3.433 5.127 1.00 0.00 ATOM 128 QB ASP 131 15.561 2.694 5.037 1.00 0.00 ATOM 129 CG ASP 131 17.165 1.652 5.275 1.00 0.00 ATOM 130 OD1 ASP 131 16.896 0.615 5.911 1.00 0.00 ATOM 131 OD2 ASP 131 18.327 2.052 5.073 1.00 0.00 ATOM 132 C ASP 131 16.248 1.191 2.517 1.00 0.00 ATOM 133 O ASP 131 16.774 1.054 1.411 1.00 0.00 ATOM 134 N LYS+ 132 15.802 0.155 3.219 1. 00 0.00 ATOM 135 H LYS+ 132 15.416 0.311 4.109 1.00 0.00 ATOM 136 CA LYS+ 132 15.910-1.205 2.712 1.00 0.00 ATOM 137 HA LYS+ 132 16.572-1.178 1.862 1.00 0.00 ATOM 138 CB LYS+ 132 16.518-2.121 3.773 1.00 0.00 ATOM 139 1HB LYS+ 132 15.945-3. 037 3.815 1.00 0.00 ATOM 140 2HB LYS+ 132 16.462-1.627 4.734 1.00 0.00 ATOM 141 QB LYS+ 132 16.204-2.332 4.274 1.00 0.00 ATOM 142 CG LYS+ 132 17.973-2.475 3.502 1.00 0.00 ATOM 143 1HG LYS+ 132 18.342-3. 083 4.317 1.00 0.00 ATOM 144 2HG LYS+ 132 18.550-1.564 3.444 1.00 0.00 ATOM 145 QG LYS+ 132 18.446-2.323 3.880 1.00 0.00 ATOM 146 CD LYS+ 132 18.131-3.246 2.197 1.00 0.00 ATOM 147 1HD LYS+ 132 17.150-3.437 1.784 1.00 0.00 ATOM 148 2HD LYS+ 132 18.621-4. 187 2.406 1.00 0.00

ATOM 149 QD LYS+ 132 17.886-3.812 2.095 1.00 0.00 ATOM 150 CE LYS+ 132 18.961-2.473 1.177 1.00 0.00 ATOM 151 1HE LYS+ 132 19.122-3.105 0.314 1.00 0.00 ATOM 152 2HE LYS+ 132 19.914-2.226 1.622 1.00 0.00 ATOM 153 QE LYS+ 132 19.518-2.665 0.968 1.00 0.00 ATOM 154 NZ LYS+ 132 18.289-1.214 0.738 1.00 0.00 ATOM 155 1HZ LYS+ 132 18.850-0.743-0.001 1.00 0.00 ATOM 156 2HZ LYS+ 132 18.186-0.555 1.544 1.00 0.00 ATOM 157 3HZ LYS+ 132 17.343-1.422 0.359 1.00 0.00 ATOM 158 QZ LYS+ 132 18.127-0.906 0.634 1.00 0.00 ATOM 159 C LYS+ 132 14.566-1.747 2.256 1.00 0.00 ATOM 160 O LYS+ 132 14.504-2.712 1.499 1.00 0.00 ATOM 161 N CYS 133 13.495-1.121 2.704 1.00 0.00 ATOM 162 H CYS 133 13.605-0.352 3.297 1.00 0.00 ATOM 163 CA CYS 133 12.157-1.546 2.324 1.00 0.00 ATOM 164 HA CYS 133 12.198-2.592 2.064 1.00 0.00 ATOM 165 CB CYS 133 11.180-1.349 3.486 1.00 0.00 ATOM 166 1HB CYS 133 10.202-1.122 3.083 1.00 0.00 ATOM 167 2HB CYS 133 11. 511-0. 514 4.084 1.00 0.00 ATOM 168 QB CYS 133 10.857-0.818 3.583 1.00 0.00 ATOM 169 SG CYS 133 10.998-2.787 4.595 1.00 0.00 ATOM 170 C CYS 133 11.684-0.749 1.117 1.00 0.00 ATOM 171 O CYS 133 12.202 0.323 0.844 1.00 0.00 ATOM 172 N LYS+ 134 10.701-1.271 0.403 1.00 0.00 ATOM 173 H LYS+ 134 10.320-2.133 0.674 1.00 0.00 ATOM 174 CA LYS+ 134 10.158-0.599-0.768 1.00 0.00 ATOM 175 HA LYS+ 134 10.879 0.134-1.100 1.00 0.00 ATOM 176 CB LYS+ 134 9.905-1.611-1.894 1.00 0.00 ATOM 177 1HB LYS+ 134 9.329-2.433-1.494 1.00 0.00 ATOM 178 2HB LYS+ 134 10.856-1.985-2.242 1.00 0.00 ATOM 179 QB LYS+ 134 10.093-2.209-1.868 1.00 0.00 ATOM 180 CG LYS+ 134 9.151-1.037-3.088 1.00 0.00 ATOM 181 1HG LYS+ 134 9.436-0.001-3.214 1.00 0.00 ATOM 182 2HG LYS+ 134 8.091-1.097-2.895 1.00 0.00 ATOM 183 QG LYS+ 134 8.764-0.549-3.055 1.00 0.00 ATOM 184 CD LYS+ 134 9.465-1.794-4.373 1.00 0.00 ATOM 185 1HD LYS+ 134 10.534-1.778-4.534 1.00 0.00 ATOM 186 2HD LYS+ 134 8.971-1.301-5.198 1.00 0.00 ATOM 187 QD LYS+ 134 9.753-1.539-4.866 1.00 0.00 ATOM 188 CE LYS+ 134 8.996-3.243-4.313 1.00 0.00 ATOM 189 1HE LYS+ 134 9.598-3.772-3.587 1.00 0.00 ATOM 190 2HE LYS+ 134 9.133-3.692-5.286 1.00 0.00 ATOM 191 QE LYS+ 134 9.366-3.732-4.437 1.00 0.00 ATOM 192 NZ LYS+ 134 7.560-3.356-3.928 1.00 0.00 ATOM 193 1HZ LYS+ 134 7.282-2.545-3.338 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.402-4.231-3.385 1.00 0.00 ATOM 195 3HZ LYS+ 134 6.959-3.375-4.777 1.00 0.00 ATOM 196 QZ LYS+ 134 7.215-3.383-3.833 1.00 0.00 ATOM 197 C LYS+ 134 8.867 0.105-0.393 1.00 0.00 ATOM 198 O LYS+ 134 7.892-0.543-0.024 1.00 0.00 ATOM 199 N PHE 135 8.866 1.423-0.477 1.00 0.00 ATOM 200 H PHE 135 9.677 1.886-0.772 1.00 0.00 ATOM 201 CA PHE 135 7.689 2.204-0.125 1.00 0.00 ATOM 202 HA PHE 135 7.111 1.634 0.587 1.00 0.00 ATOM 203 CB PHE 135 8.115 3.527 0.515 1.00 0.00 ATOM 204 1HB PHE 135 8.551 4.159-0.248 1.00 0.00 ATOM 205 2HB PHE 135 8.857 3.329 1.273 1.00 0.00 ATOM 206 QB PHE 135 8.704 3.744 0.512 1.00 0.00 ATOM 207 QD PHE 135 6.874 4.380 1.235 1.00 0.00 ATOM 208 QE PHE 135 5.061 5.645 2.309 1.00 0.00 ATOM 209 QR PHE 135 5.604 5.265 1.988 1.00 0.00 ATOM 210 CG PHE 135 6.997 4.294 1.162 1.00 0.00 ATOM 211 CD1 PHE 135 7.016 5.678 1.179 1.00 0.00 ATOM 212 1HD PHE 135 7.839 6.202 0.713 1.00 0.00 ATOM 213 CE1 PHE 135 5.999 6.391 1.781 1.00 0.00 ATOM 214 1HE PHE 135 6.027 7.471 1.787 1.00 0.00 ATOM 215 CZ PHE 135 4.948 5.723 2.376 1.00 0.00 ATOM 216 HZ PHE 135 4.150 6.278 2.849 1.00 0.00 ATOM 217 CE2 PHE 135 4.916 4.344 2.365 1.00 0.00 ATOM 218 2HE PHE 135 4.094 3.818 2.832 1.00 0.00 ATOM 219 CD2 PHE 135 5.936 3.636 1.762 1.00 0.00 ATOM 220 2HD PHE 135 5.909 2.557 1.757 1.00 0.00

ATOM 221 C PHE 135 6.836 2.470-1.355 1.00 0.00 ATOM 222 O PHE 135 7.315 3.007-2.352 1.00 0.00 ATOM 223 N LEU 136 5.573 2.085-1.277 1.00 0.00 ATOM 224 H LEU 136 5.252 1.657-0.451 1.00 0.00 ATOM 225 CA LEU 136 4.645 2.278-2.372 1.00 0.00 ATOM 226 HA LEU 136 5.170 2.791-3.165 1.00 0.00 ATOM 227 CB LEU 136 4.130 0.935-2.896 1.00 0.00 ATOM 228 1HB LEU 136 3.383 1.133-3.650 1.00 0.00 ATOM 229 2HB LEU 136 3.656 0.413-2.076 1.00 0.00 ATOM 230 QB LEU 136 3.520 0.773-2.863 1.00 0.00 ATOM 231 CG LEU 136 5.192 0.019-3.502 1.00 0.00 ATOM 232 HG LEU 136 6.060 0.607-3.761 1.00 0.00 ATOM 233 QD1 LEU 136 5.719-1.282-2.258 1.00 0.00 ATOM 234 QD2 LEU 136 4.546-0.791-5.069 1.00 0.00 ATOM 235 CD1 LEU 136 5.619-1.033-2.498 1.00 0.00 ATOM 236 1HD1 LEU 136 6.683-0.963-2.332 1.00 0.00 ATOM 237 2HD1 LEU 136 5.375-2.014-2.877 1.00 0.00 ATOM 238 3HD1 LEU 136 5.099-0.870-1.564 1.00 0.00 ATOM 239 CD2 LEU 136 4.670-0.637-4.769 1.00 0.00 ATOM 240 1HD2 LEU 136 5.446-0.642-5.519 1.00 0.00 ATOM 241 2HD2 LEU 136 3.819-0.082-5.136 1.00 0.00 ATOM 242 3HD2 LEU 136 4.371-1.651-4.553 1.00 0.00 ATOM 243 QQD LEU 136 5. 132-1.037-3.664 1.00 0.00 ATOM 244 C LEU 136 3.476 3.135-1.917 1.00 0.00 ATOM 245 O LEU 136 2.422 2.622-1.548 1.00 0.00 ATOM 246 N HIS+ 137 3.673 4.440-1.952 1.00 0.00 ATOM 247 H HIS+ 137 4.538 4.782-2.261 1.00 0.00 ATOM 248 CA HIS+ 137 2.642 5.388-1.559 1.00 0.00 ATOM 249 HA HIS+ 137 1.967 4.902-0.857 1.00 0.00 ATOM 250 CB HIS+ 137 3.295 6.609-0.904 1.00 0.00 ATOM 251 1HB HIS+ 137 3.664 7.257-1.680 1.00 0.00 ATOM 252 2HB HIS+ 137 4.124 6.280-0.295 1.00 0.00 ATOM 253 QB HIS+ 137 3.894 6.769-0.988 1.00 0.00 ATOM 254 CG HIS+ 137 2.383 7.412-0.032 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.251 8.046-0.491 1.00 0.00 ATOM 256 CD2 HIS+ 137 2.442 7.671 1.292 1.00 0.00 ATOM 257 1HD HIS+ 137 0.926 8.060-1.426 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.656 8.655 0.516 1.00 0.00 ATOM 259 NE2 HIS+ 137 1.354 8.442 1.618 1.00 0.00 ATOM 260 2HD HIS+ 137 3.208 7.331 1.973 1.00 0.00 ATOM 261 1HE HIS+ 137-0.258 9.231 0.451 1.00 0.00 ATOM 262 2HE HIS+ 137 0.973 8.494 2.527 1.00 0.00 ATOM 263 C HIS+ 137 1.882 5.822-2.805 1.00 0.00 ATOM 264 O HIS+ 137 2.377 6.640-3.578 1.00 0.00 ATOM 265 N GLN 138 0.704 5.253-3.026 1.00 0.00 ATOM 266 H GLN 138 0.361 4.584-2.392 1.00 0.00 ATOM 267 CA GLN 138-0.074 5.584-4.215 1.00 0.00 ATOM 268 HA GLN 138 0.343 6.483-4.644 1.00 0.00 ATOM 269 CB GLN 138 0.021 4.447-5.246 1.00 0.00 ATOM 270 1HB GLN 138-0.058 4.872-6.236 1.00 0.00 ATOM 271 2HB GLN 138-0.805 3.770-5.090 1.00 0.00 ATOM 272 QB GLN 138-0.431 4.321-5.663 1.00 0.00 ATOM 273 CG GLN 138 1.316 3.641-5.178 1.00 0.00 ATOM 274 1HG GLN 138 1.093 2.610-5.410 1.00 0.00 ATOM 275 2HG GLN 138 1.711 3.704-4.175 1.00 0.00 ATOM 276 QG GLN 138 1.402 3.157-4.793 1.00 0.00 ATOM 277 CD GLN 138 2.375 4.136-6.146 1.00 0.00 ATOM 278 OE1 GLN 138 2.087 4.403-7.311 1.00 0.00 ATOM 279 NE2 GLN 138 3.611 4.255-5.670 1.00 0.00 ATOM 280 1HE2 GLN 138 3.772 4.023-4.734 1.00 0.00 ATOM 281 2HE2 GLN 138 4.312 4.573-6.277 1.00 0.00 ATOM 282 QE2 GLN 138 4.042 4.298-5.506 1.00 0.00 ATOM 283 C GLN 138-1.542 5.834-3.872 1.00 0.00 ATOM 284 O GLN 138-2.183 5.019-3.202 1.00 0.00 ATOM 285 N GLU 139-2.072 6.958-4.343 1.00 0.00 ATOM 286 H GLU 139-1.513 7.563-4.873 1.00 0.00 ATOM 287 CA GLU 139-3.464 7.314-4.096 1.00 0.00 ATOM 288 HA GLU 139-3.790 6.776-3.218 1.00 0.00 ATOM 289 CB GLU 139-3.605 8.822-3.836 1.00 0.00 ATOM 290 1HB GLU 139-4.091 8.965-2.881 1. 00 0.00 ATOM 291 2HB GLU 139-4.220 9.253-4.610 1.00 0.00 ATOM 292 QB GLU 139-4.155 9.109-3.746 1.00 0.00

ATOM 293 CG GLU 139-2.282 9.577-3.808 1.00 0.00 ATOM 294 1HG GLU 139-2.479 10.630-3.947 1.00 0.00 ATOM 295 2HG GLU 139-1.658 9.220-4.612 1.00 0.00 ATOM 296 QG GLU 139-2.068 9.925-4.280 1.00 0.00 ATOM 297 CD GLU 139-1. 540 9.393-2.503 1.00 0.00 ATOM 298 OE1 GLU 139-2. 092 9.768-1.449 1.00 0.00 ATOM 299 OE2 GLU 139-0. 411 8.862-2.537 1.00 0.00 ATOM 300 C GLU 139-4.342 6.905-5.277 1.00 0.00 ATOM 301 O GLU 139-4.339 7.554-6.325 1.00 0.00 ATOM 302 N ARG+ 140-5.096 5.830-5.105 1.00 0.00 ATOM 303 H ARG+ 140-5.066 5.356-4.246 1.00 0.00 ATOM 304 CA ARG+ 140-5.985 5.341-6.151 1.00 0.00 ATOM 305 HA ARG+ 140-5.651 5.757-7.090 1.00 0.00 ATOM 306 CB ARG+ 140-5.932 3.810-6.226 1.00 0.00 ATOM 307 1HB ARG+ 140-6.384 3.405-5.330 1.00 0.00 ATOM 308 2HB ARG+ 140-4.900 3.499-6.268 1.00 0.00 ATOM 309 QB ARG+ 140-5.642 3.452-5.799 1.00 0.00 ATOM 310 CG ARG+ 140-6. 657 3.220-7.427 1.00 0.00 ATOM 311 1HG ARG+ 140-7.552 3.796-7.614 1.00 0.00 ATOM 312 2HG ARG+ 140-6.926 2.198-7.203 1.00 0.00 ATOM 313 QG ARG+ 140-7.239 2.997-7.409 1.00 0.00 ATOM 314 CD ARG+ 140-5.786 3.237-8.672 1.00 0.00 ATOM 315 1HD ARG+ 140-5.654 2.221-9.018 1.00 0.00 ATOM 316 2HD ARG+ 140-4.826 3.658-8.417 1.00 0.00 ATOM 317 QD ARG+ 140-5.240 2.940-8.718 1.00 0.00 ATOM 318 NE ARG+ 140-6.386 4.028-9.743 1.00 0.00 ATOM 319 HE ARG+ 140-7.374 4.029-9.811 1.00 0.00 ATOM 320 CZ ARG+ 140-5.686 4.746-10.620 1.00 0.00 ATOM 321 NH1 ARG+ 140-4.357 4.745-10.571 1.00 0.00 ATOM 322 1HH1 ARG+ 140-3. 883 4.204-9.876 1.00 0.00 ATOM 323 2HH1 ARG+ 140-3.829 5.282-11.229 1.00 0.00 ATOM 324 QH1 ARG+ 140-3.856 4.743-10.553 1.00 0.00 ATOM 325 NH2 ARG+ 140-6.313 5.453-11.550 1.00 0.00 ATOM 326 1HH2 ARG+ 140-7.328 5.444-11.591 1.00 0.00 ATOM 327 2HH2 ARG+ 140-5.797 5.996-12.208 1.00 0.00 ATOM 328 QH2 ARG+ 140-6.562 5.720-11.900 1.00 0.00 ATOM 329 C ARG+ 140-7.407 5.808-5.883 1.00 0.00 ATOM 330 O ARG+ 140-8.226 5.061-5.351 1.00 0.00 ATOM 331 N MET 141-7.693 7.051-6.252 1.00 0.00 ATOM 332 H MET 141-6. 991 7.591-6.669 1.00 0.00 ATOM 333 CA MET 141-9.017 7.646-6.049 1.00 0.00 ATOM 334 HA MET 141-9.303 7.472-5.023 1.00 0.00 ATOM 335 CB MET 141-8.931 9.157-6.295 1.00 0.00 ATOM 336 1HB MET 141-9.143 9.349-7.338 1.00 0.00 ATOM 337 2HB MET 141-7.927 9.488-6.077 1.00 0.00 ATOM 338 QB MET 141-8.535 9.419-6.708 1.00 0.00 ATOM 339 CG MET 141-9.895 9.981-5.455 1.00 0.00 ATOM 340 1HG MET 141-9.410 10.233-4.522 1.00 0.00 ATOM 341 2HG MET 141-10.773 9.386-5.253 1.00 0.00 ATOM 342 QG MET 141-10.091 9.810-4.888 1.00 0.00 ATOM 343 SD MET 141-10.409 11.507-6.268 1.00 0.00 ATOM 344 QE MET 141-10.941 10.787-8.226 1.00 0.00 ATOM 345 CE MET 141-10.852 10.907-7.898 1.00 0.00 ATOM 346 1HE MET 141-10.968 9.832-7.868 1.00 0.00 ATOM 347 2HE MET 141-10.073 11.166-8.601 1.00 0.00 ATOM 348 3HE MET 141-11.782 11.361-8.208 1.00 0.00 ATOM 349 C MET 141-10.070 7.019-6.974 1.00 0.00 ATOM 350 O MET 141-11.091 7.640-7.279 1.00 0.00 ATOM 351 N ASP 142-9. 821 5.789-7.397 1.00 0.00 ATOM 352 H ASP 142-9.001 5.345-7.101 1.00 0.00 ATOM 353 CA ASP 142-10.727 5.068-8.275 1.00 0.00 ATOM 354 HA ASP 142-11.415 5.776-8.710 1.00 0.00 ATOM 355 CB ASP 142-9. 936 4.378-9.392 1.00 0.00 ATOM 356 1HB ASP 142-10.590 3.693-9.907 1.00 0.00 ATOM 357 2HB ASP 142-9.122 3.823-8.954 1.00 0.00 ATOM 358 QB ASP 142-9.856 3. 758-9. 431 1.00 0.00 ATOM 359 CG ASP 142-9.360 5.342-10.406 1.00 0.00 ATOM 360 OD1 ASP 142-9.366 6.559-10.152 1.00 0.00 ATOM 361 OD2 ASP 142-8.869 4.871-11.450 1.00 0.00 ATOM 362 C ASP 142-11.503 4.016-7.497 1.00 0.00 ATOM 363 0 ASP 142-12.730 3.960-7.550 1.00 0.00 ATOM 364 N VAL 143-10.768 3.168-6.790 1.00 0.00

ATOM 365 H VAL 143-9.793 3.259-6.802 1.00 0.00 ATOM 366 CA VAL 143-11.370 2.091-6.020 1.00 0.00 ATOM 367 HA VAL 143-12.326 1.861-6.468 1.00 0.00 ATOM 368 CB VAL 143-10.489 0.821-6.071 1.00 0.00 ATOM 369 HB VAL 143-9.844 0.821-5.202 1.00 0.00 ATOM 370 QG1 VAL 143-11.547-0.727-6.012 1.00 0.00 ATOM 371 QG2 VAL 143-9.401 0.808-7.609 1.00 0.00 ATOM 372 CG1 VAL 143-11.346-0.431-6.022 1.00 0.00 ATOM 373 1HG1 VAL 143-11. 960-0.479-6.909 1.00 0.00 ATOM 374 2HG1 VAL 143-11.975-0.404-5.146 1.00 0.00 ATOM 375 3HG1 VAL 143-10.706-1.300-5.981 1.00 0.00 ATOM 376 CG2 VAL 143-9.609 0.811-7.315 1.00 0.00 ATOM 377 lHG2 VAL 143-9.656-0.163-7.781 1.00 0.00 ATOM 378 2HG2 VAL 143-8.588 1.027-7.036 1.00 0.00 ATOM 379 3HG2 VAL 143-9.959 1.560-8.011 1.00 0.00 ATOM 380 QQG VAL 143-10.474 0.040-6.811 1.00 0.00 ATOM 381 C VAL 143-11.596 2.515-4.566 1.00 0.00 ATOM 382 O VAL 143-10.887 3.371-4.042 1.00 0.00 ATOM 383 N CYS 144-12.597 1.919-3.925 1.00 0.00 ATOM 384 H CYS 144-13.132 1.250-4.395 1.00 0.00 ATOM 385 CA CYS 144-12.931 2.245-2.539 1.00 0.00 ATOM 386 HA CYS 144-12.067 2.712-2.080 1.00 0.00 ATOM 387 CB CYS 144-14.108 3.221-2.500 1.00 0.00 ATOM 388 1HB CYS 144-14.289 3.509-1.476 1.00 0.00 ATOM 389 2HB CYS 144-14.985 2.727-2.888 1.00 0.00 ATOM 390 QB CYS 144-14.637 3.118-2.182 1.00 0.00 ATOM 391 SG CYS 144-13.858 4.744-3.471 1.00 0.00 ATOM 392 C CYS 144-13.287 0.992-1.754 1.00 0.00 ATOM 393 O CYS 144-14.441 0.555-1.759 1.00 0.00 ATOM 394 N GLU 145-12.300 0.417-1.083 1.00 0.00 ATOM 395 H GLU 145-11.403 0.808-1.117 1.00 0.00 ATOM 396 CA GLU 145-12.510-0.786-0.304 1.00 0.00 ATOM 397 HA GLU 145-13.553-1.052-0.381 1.00 0.00 ATOM 398 CB GLU 145-11.674-1.919-0.879 1.00 0.00 ATOM 399 1HB GLU 145-11.390-2.585-0.081 1.00 0.00 ATOM 400 2HB GLU 145-10.782-1.502-1.321 1.00 0.00 ATOM 401 QB GLU 145-11.086-2.043-0.701 1.00 0.00 ATOM 402 CG GLU 145-12.415-2.723-1.931 1.00 0.00 ATOM 403 1HG GLU 145-11.897-3.659-2.085 1.00 0.00 ATOM 404 2HG GLU 145-12.431-2.163-2.853 1.00 0.00 ATOM 405 QG GLU 145-12.164-2.911-2.469 1.00 0.00 ATOM 406 CD GLU 145-13.839-3.019-1.517 1.00 0.00 ATOM 407 OE1 GLU 145-14.751-2.830-2.338 1.00 0.00 ATOM 408 OE2 GLU 145-14.047-3.413-0.346 1.00 0.00 ATOM 409 C GLU 145-12.164-0.577 1.158 1.00 0.00 ATOM 410 O GLU 145-11.745 0.507 1.562 1.00 0.00 ATOM 411 N THR 146-12.351-1.628 1.940 1.00 0.00 ATOM 412 H THR 146-12. 692-2.457 1.545 1.00 0.00 ATOM 413 CA THR 146-12.076-1.594 3.366 1.00 0.00 ATOM 414 HA THR 146-12.449-0.657 3.759 1.00 0.00 ATOM 415 CB THR 146-12.811-2.753 4.043 1.00 0.00 ATOM 416 HB THR 146-12.152-3.610 4.074 1. 00 0. 00 ATOM 417 QG2 THR 146-13.350-2.382 5.802 1.00 0.00 ATOM 418 OG1 THR 146-13.970-3.107 3.302 1.00 0.00 ATOM 419 1HG THR 146-14.282-3.971 3.589 1.00 0.00 ATOM 420 CG2 THR 146-13. 247-2.455 5.463 1.00 0.00 ATOM 421 1HG2 THR 146-13.207-1.388 5.637 1.00 0.00 ATOM 422 2HG2 THR 146-12.587-2. 955 6.157 1.00 0.00 ATOM 423 3HG2 THR 146-14.258-2.805 5.613 1.00 0.00 ATOM 424 C THR 146-10.573-1.687 3.632 1.00 0.00 ATOM 425 O THR 146-9.790-2.001 2.730 1.00 0.00 ATOM 426 N HIS+ 147-10.179-1.419 4.876 1.00 0.00 ATOM 427 H HIS+ 147-10. 858-1. 176 5.545 1.00 0. 00 ATOM 428 CA HIS+ 147-8.775-1.472 5.284 1.00 0.00 ATOM 429 HA HIS+ 147-8.239-0.711 4.737 1.00 0.00 ATOM 430 CB HIS+ 147-8. 657-1. 183 6.783 1.00 0.00 ATOM 431 1HB HIS+ 147-8.600-2.121 7.318 1.00 0.00 ATOM 432 2HB HIS+ 147-9. 534-0.643 7.107 1.00 0.00 ATOM 433 QB HIS+ 147-9.067-1.382 7.212 1.00 0. 00 ATOM 434 CG HIS+ 147-7, 455-0. 370 7.150 1.00 0. 00 ATOM 435 ND1 HIS+ 147-7. 499 0. 995 7.332 1.00 0.00 ATOM 436 CD2 HIS+ 147-6.169-0.736 7.372 1.00 0.00

ATOM 437 1HD HIS+ 147-8.299 1.562 7.240 1.00 0.00 ATOM 438 CE1 HIS+ 147-6.293 1.435 7.648 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.465 0.405 7.681 1.00 0.00 ATOM 440 2HD HIS+ 147-5.768-1.740 7.305 1.00 0.00 ATOM 441 1HE HIS+ 147-6.029 2.465 7.845 1.00 0.00 ATOM 442 2HE HIS+ 147-4.487 0.479 7.671 1.00 0.00 ATOM 443 C HIS+ 147-8. 150-2.833 4.980 1.00 0.00 ATOM 444 0 HIS+ 147-6. 966-2.924 4.659 1.00 0.00 ATOM 445 N LEU 148-8.954-3.886 5.090 1.00 0.00 ATOM 446 H LEU 148-9.886-3.748 5.353 1.00 0.00 ATOM 447 CA LEU 148-8.480-5.242 4.836 1.00 0.00 ATOM 448 HA LEU 148-7.559-5.375 5.384 1.00 0.00 ATOM 449 CB LEU 148-9.505-6.266 5.336 1.00 0.00 ATOM 450 1HB LEU 148-10.204-6.465 4.538 1.00 0.00 ATOM 451 2HB LEU 148-10.044-5.828 6.164 1.00 0.00 ATOM 452 QB LEU 148-10.124-6.146 5.351 1.00 0.00 ATOM 453 CG LEU 148-8.915-7.600 5.799 1.00 0.00 ATOM 454 HG LEU 148-7.842-7.502 5.886 1.00 0.00 ATOM 455 QD1 LEU 148-9.591-8.078 7.487 1.00 0.00 ATOM 456 QD2 LEU 148-9.275-8.955 4.547 1.00 0.00 ATOM 457 CD1 LEU 148-9.463-7.985 7.163 1.00 0.00 ATOM 458 1HD1 LEU 148-9.400-7.139 7.830 1.00 0.00 ATOM 459 2HD1 LEU 148-8.881-8.803 7.565 1.00 0.00 ATOM 460 3HD1 LEU 148-10.493-8.293 7.065 1.00 0.00 ATOM 461 CD2 LEU 148-9.207-8.695 4.786 1.00 0.00 ATOM 462 1HD2 LEU 148-10.191-8.546 4.366 1.00 0.00 ATOM 463 2HD2 LEU 148-9.167-9.657 5.276 1.00 0.00 ATOM 464 3HD2 LEU 148-8. 469-8.663 3.998 1.00 0.00 ATOM 465 QQD LEU 148-9.433-8.517 6.017 1.00 0.00 ATOM 466 C LEU 148-8.199-5.468 3.355 1.00 0.00 ATOM 467 O LEU 148-7.212-6.107 3.002 1.00 0.00 ATOM 468 N HIS+ 149-9.070-4.953 2.490 1.00 0.00 ATOM 469 H HIS+ 149-9.843-4.455 2.824 1.00 0.00 ATOM 470 CA HIS+ 149-8.891-5.129 1.053 1.00 0.00 ATOM 471 HA HIS+ 149-8. 832-6.193 0.875 1.00 0.00 ATOM 472 CB HIS+ 149-10.076-4.580 0.261 1.00 0.00 ATOM 473 1HB HIS+ 149-9.717-3.863-0.464 1.00 0.00 ATOM 474 2HB HIS+ 149-10.768-4.089 0.931 1.00 0.00 ATOM 475 QB HIS+ 149-10.242-3.976 0.233 1.00 0.00 ATOM 476 CG HIS+ 149-10.812-5.658-0.479 1.00 0.00 ATOM 477 ND1 HIS+ 149-12.179-5.665-0.659 1.00 0.00 ATOM 478 CD2 HIS+ 149-10.350-6.782-1.080 1.00 0.00 ATOM 479 1HD HIS+ 149-12.807-4.963-0.359 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.525-6.749-1.336 1.00 0.00 ATOM 481 NE2 HIS+ 149-11.434-7.442-1.605 1.00 0.00 ATOM 482 2HD HIS+ 149-9. 317-7.099-1.141 1.00 0.00 ATOM 483 1HE HIS+ 149-13.531-7.019-1.624 1.00 0.00 ATOM 484 2HE HIS+ 149-11. 389-8.204-2.221 1.00 0.00 ATOM 485 C HIS+ 149-7.590-4.507 0.572 1.00 0.00 ATOM 486 O HIS+ 149-6.789-5.183-0.064 1.00 0.00 ATOM 487 N TRP 150-7.368-3.234 0.887 1.00 0.00 ATOM 488 H TRP 150-8.040-2.741 1.407 1.00 0.00 ATOM 489 CA TRP 150-6. 130-2.561 0.483 1.00 0.00 ATOM 490 HA TRP 150-6. 046-2. 623-0.593 1.00 0.00 ATOM 491 CB TRP 150-6.122-1.097 0.917 1.00 0.00 ATOM 492 1HB TRP 150-5. 149-0.677 0.701 1.00 0.00 ATOM 493 2HB TRP 150-6.295-1.047 1.981 1.00 0.00 ATOM 494 QB TRP 150-5. 722-0.862 1.341 1.00 0.00 ATOM 495 CG TRP 150-7. 149-0.238 0.250 1.00 0.00 ATOM 496 CD1 TRP 150-7.628 0.949 0.717 1.00 0.00 ATOM 497 CD2 TRP 150-7. 818-0.480-0.994 1.00 0.00 ATOM 498 CE3 TRP 150-7.771-1.503-1.946 1.00 0.00 ATOM 499 CE2 TRP 150-8.686 0.602-1.212 1.00 0.00 ATOM 500 NE1 TRP 150-8. 553 1.457-0.156 1.00 0.00 ATOM 501 HD TRP 150-7.316 1.408 1.643 1.00 0.00 ATOM 502 3HE TRP 150-7.120-2.352-1.820 1.00 0.00 ATOM 503 CZ3 TRP 150-8.577-1.412-3.060 1.00 0.00 ATOM 504 CZ2 TRP 150-9.496 0.693-2.335 1.00 0.00 ATOM 505 1HE TRP 150-9.041 2.299-0.043 1.00 0.00 ATOM 506 3HZ TRP 150-8.558-2.195-3.801 1.00 0.00 ATOM 507 CH2 TRP 150-9.428-0.322-3.245 1.00 0.00 ATOM 508 2HZ TRP 150-10.162 1.532-2.495 1. 00 0.00

ATOM 509 HH TRP 150-10.043-0.293-4.133 1.00 0.00 ATOM 510 C TRP 150-4.932-3.254 1.087 1.00 0.00 ATOM 511 O TRP 150-3.877-3.313 0.472 1.00 0.00 ATOM 512 N HIS+ 151-5.102-3.789 2.287 1.00 0.00 ATOM 513 H HIS+ 151-5.977-3.717 2.726 1.00 0.00 ATOM 514 CA HIS+ 151-4. 027-4.498 2.954 1.00 0.00 ATOM 515 HA HIS+ 151-3.190-3.824 3.049 1.00 0.00 ATOM 516 CB HIS+ 151-4.479-4.959 4.347 1.00 0.00 ATOM 517 1HB HIS+ 151-5.303-5.650 4.234 1.00 0.00 ATOM 518 2HB HIS+ 151-4.816-4.100 4.907 1.00 0.00 ATOM 519 QB HIS+ 151-5.059-4.875 4.570 1.00 0.00 ATOM 520 CG HIS+ 151-3. 414-5.643 5.152 1.00 0.00 ATOM 521 ND1 HIS+ 151-3.086-5.271 6.438 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.612-6.692 4.851 1.00 0.00 ATOM 523 1HD HIS+ 151-3.492-4.535 6.944 1.00 0.00 ATOM 524 CE1 HIS+ 151-2.130-6.062 6.891 1.00 0.00 ATOM 525 NE2 HIS+ 151-1. 826-6.934 5.950 1.00 0.00 ATOM 526 2HD HIS+ 151-2.588-7.225 3.907 1.00 0.00 ATOM 527 1HE HIS+ 151-1.663-5.996 7.865 1.00 0.00 ATOM 528 2HE HIS+ 151-1.257-7.722 6.079 1.00 0.. 00 ATOM 529 C HIS+ 151-3.612-5.690 2.106 1.00 0.00 ATOM 530 O HIS+ 151-2. 426-5.918 1.875 1.00 0.00 ATOM 531 N THR 152-4.600-6.440 1.642 1.00 0.00 ATOM 532 H THR 152-5.525-6.201 1.857 1.00 0.00 ATOM 533 CA THR 152-4.346-7.603 0.813 1.00 0.00 ATOM 534 HA THR 152-3.590-8.197 1.305 1.00 0.00 ATOM 535 CB THR 152-5.618-8.445 0.662 1.00 0.00 ATOM 536 HB THR 152-6.205-8.051-0.156 1.00 0.00 ATOM 537 QG2 THR 152-5.278-10.253 0.303 1.00 0.00 ATOM 538 OG1 THR 152-6.398-8.391 1.846 1.00 0.00 ATOM 539 1HG THR 152-6.663-7.482 2.019 1.00 0.00 ATOM 540 CG2 THR 152-5.344-9.905 0.374 1.00 0.00 ATOM 541 1HG2 THR 152-4.458-10.219 0.905 1.00 0.00 ATOM 542 2HG2 THR 152-5.192-10.041-0.690 1.00 0.00 ATOM 543 3HG2 THR 152-6.186-10.499 0.694 1.00 0.00 ATOM 544 C THR 152-3.809-7.189-0.549 1.00 0.00 ATOM 545 O THR 152-2. 809-7.730-0.987 1.00 0.00 ATOM 546 N VAL 153-4.453-6.216-1.198 1.00 0.00 ATOM 547 H VAL 153-5.241-5.798-0.784 1.00 0.00 ATOM 548 CA VAL 153-3. 995-5. 746-2.508 1.00 0. 00 ATOM 549 HA VAL 153-4.047-6.578-3.192 1.00 0.00 ATOM 550 CB VAL 153-4.884-4.604-3.053 1.00 0.00 ATOM 551 HB VAL 153-4.821-3.768-2.371 1.00 0.00 ATOM 552 QG1 VAL 153-4.287-4.033-4.743 1.00 0.00 ATOM 553 QG2 VAL 153-6.679-5.155-3.148 1.00 0.00 ATOM 554 CG1 VAL 153-4.402-4.142-4.420 1.00 0.00 ATOM 555 1HG1 VAL 153-4.970-4.644-5.189 1.00 0.00 ATOM 556 2HG1 VAL 153-3.354-4.382-4.532 1.00 0.00 ATOM 557 3HG1 VAL 153-4.539-3.075-4.509 1.00 0.00 ATOM 558 CG2 VAL 153-6.336-5.049-3.130 1.00 0.00 ATOM 559 1HG2 VAL 153-6.883-4.385-3.782 1.00 0. 00 ATOM 560 2HG2 VAL 153-6.773-5.026-2.142 1.00 0.00 ATOM 561 3HG2 VAL 153-6.382-6.056-3.521 1.00 0.00 ATOM 562 QQG VAL 153-5.483-4.594-3.946 1.00 0.00 ATOM 563 C VAL 153-2.550-5.280-2.426 1.00 0.00 ATOM 564 O VAL 153-1.715-5.640-3.258 1.00 0.00 ATOM 565 N ALA 154-2.260-4.498-1.400 1.00 0.00 ATOM 566 H ALA 154-2.975-4.261-0.763 1.00 0.00 ATOM 567 CA ALA 154-0.916-3.998-1.176 1.00 0.00 ATOM 568 HA ALA 154-0.602-3.451-2.053 1.00 0.00 ATOM 569 QB ALA 154-0.908-2.831 0.293 1.00 0.00 ATOM 570 CB ALA 154-0. 910-3. 055 0.011 1.00 0.00 ATOM 571 1HB ALA 154-0.304-2.191-0.220 1.00 0.00 ATOM 572 2HB ALA 154-0.500-3.564 0.871 1.00 0.00 ATOM 573 3HB ALA 154-1.921-2.740 0.227 1.00 0.00 ATOM 574 C ALA 154 0.050-5. 152-0.935 1.00 0.00 ATOM 575 O ALA 154 1.113-5.230-1.555 1.00 0.00 ATOM 576 N LYS+ 155-0.332-6.052-0.029 1.00 0.00 ATOM 577 H LYS+ 155-1.195-5.933 0.427 1.00 0.00 ATOM 578 CA LYS+ 155 0. 490-7. 210 0.301 1.00 0.00 ATOM 579 HA LYS+ 155 1.453-6.849 0.646 1.00 0.00 ATOM 580 CB LYS+ 155-0.166-8.046 1.408 1.00 0.00

ATOM 581 1HB LYS+ 155-1.201-8.214 1.143 1.00 0.00 ATOM 582 2HB LYS+ 155-0.130-7.492 2.333 1.00 0.00 ATOM 583 QB LYS+ 155-0. 665-7. 853 1.738 1.00 0.00 ATOM 584 CG LYS+ 155 0. 494-9.403 1.631 1.00 0.00 ATOM 585 1HG LYS+ 155 1.317-9.508 0.939 1.00 0.00 ATOM 586 2HG LYS+ 155-0. 234-10.180 1.446 1.00 0.00 ATOM 587 QG LYS+ 155 0.542-9. 844 1.192 1.00 0.00 ATOM 588 CD LYS+ 155 1.020-9.550 3.053 1.00 0. 00 ATOM 589 1HD LYS+ 155 0. 211-9. 363 3.745 1.00 0.00 ATOM 590 2HD LYS+ 155 1.804-8.823 3.213 1.00 0.00 ATOM 591 QD LYS+ 155 1.008-9. 093 3.479 1.00 0.00 ATOM 592 CE LYS+ 155 1.581-10. 946 3.311 1.00 0.00 ATOM 593 1HE LYS+ 155 0.945-11.446 4.031 1.00 0.00 ATOM 594 2HE LYS+ 155 2.576-10.850 3.722 1.00 0.00 ATOM 595 QE LYS+ 155 1.761-11.148 3.876 1.00 0.00 ATOM 596 NZ LYS+ 155 1.650-11.771 2.068 1.00 0.00 ATOM 597 1HZ LYS+ 155 0.697-11.919 1.679 1.00 0.00 ATOM 598 2HZ LYS+ 155 2.073-12.699 2.275 1.00 0.00 ATOM 599 3HZ LYS+ 155 2.237-11.292 1.344 1.00 0.00 ATOM 600 QZ LYS+ 155 1.669-11. 970 1.766 1.00 0.00 ATOM 601 C LYS+ 155 0.709-8.072-0.930 1.00 0.00 ATOM 602 O LYS+ 155 1.835-8. 461-1.207 1.00 0.00 ATOM 603 N GLU 156-0. 370-8.364-1.656 1.00 0.00 ATOM 604 H GLU 156-1.250-8.019-1.370 1.00 0.00 ATOM 605 CA GLU 156-0.294-9.181-2.863 1.00 0.00 ATOM 606 HA GLU 156 0.051-10.162-2.577 1.00 0.00 ATOM 607 CB GLU 156-1.669-9. 312-3.526 1.00 0.00 ATOM 608 1HB GLU 156-1.539-9.705-4.524 1.00 0.00 ATOM 609 2HB GLU 156-2.122-8.333-3.592 1.00 0.00 ATOM 610 QB GLU 156-1.830-9.019-4.058 1.00 0.00 ATOM 611 CG GLU 156-2.630-10.224-2.781 1.00 0.00 ATOM 612 1HG GLU 156-2.447-10.133-1.721 1.00 0.00 ATOM 613 2HG GLU 156-2.456-11.243-3.092 1.00 0.00 ATOM 614 QG GLU 156-2.451-10.688-2.407 1.00 0.00 ATOM 615 CD GLU 156-4.080-9.877-3.053 1.00 0.00 ATOM 616 OE1 GLU 156-4.342-8.754-3.535 1.00 0.00 ATOM 617 OE2 GLU 156-4.955-10. 723-2.778 1.00 0.00 ATOM 618 C GLU 156 0.698-8.584-3.852 1.00 0.00 ATOM 619 O GLU 156 1.591-9.273-4.322 1.00 0.00 ATOM 620 N THR 157 0.542-7.297-4.151 1.00 0. 00 ATOM 621 H THR 157-0.195-6. 796-3.733 1.00 0.00 ATOM 622 CA THR 157 1.436-6.608-5.084 1.00 0.00 ATOM 623 HA THR 157 1.293-7. 053-6.058 1.00 0.00 ATOM 624 CB THR 157 1.071-5.120-5.160 1.00 0.00 ATOM 625 HB THR 157 1.284-4. 658-4.206 1.00 0.00 ATOM 626 QG2 THR 157 2.019-4.180-6.475 1.00 0.00 ATOM 627 OG1 THR 157-0.308-4.952-5.440 1.00 0.00 ATOM 628 1HG THR 157-0.835-5.279-4.696 1.00 0.00 ATOM 629 CG2 THR 157 1.837-4.361-6.222 1.00 0. 00 ATOM 630 1HG2 THR 157 1.175-4.126-7.042 1.00 0.00 ATOM 631 2HG2 THR 157 2.653-4.970-6.581 1.00 0.00 ATOM 632 3HG2 THR 157 2.228-3.446-5.801 1.00 0.00 ATOM 633 C THR 157 2.913-6.770-4.688 1.00 0.00 ATOM 634 O THR 157 3.785-6. 913-5.547 1.00 0.00 ATOM 635 N CYS 158 3.194-6. 741-3.391 1.00 0.00 ATOM 636 H CYS 158 2.465-6. 617-2.742 1.00 0.00 ATOM 637 CA CYS 158 4.567-6.883-2.915 1.00 0.00 ATOM 638 HA CYS 158 5.209-6.394-3.632 1.00 0.00 ATOM 639 CB CYS 158 4.730-6. 192-1.560 1.00 0.00 ATOM 640 1HB CYS 158 5.583-6.601-1.050 1.00 0.00 ATOM 641 2HB CYS 158 3.848-6.376-0.967 1.00 0.00 ATOM 642 QB CYS 158 4.716-6.488-1.009 1.00 0.00 ATOM 643 SG CYS 158 4.953-4. 381-1.684 1.00 0.00 ATOM 644 C CYS 158 4.978-8. 357-2.826 1.00 0.00 ATOM 645 O CYS 158 6.087-8. 717-3.226 1.00 0.00 ATOM 646 N SER 159 4.086-9.194-2.297 1.00 0.00 ATOM 647 H SER 159 3.226-8. 835-1.991 1.00 0.00 ATOM 648 CA SER 159 4.341-10.627-2.141 1.00 0.00 ATOM 649 HA SER 159 5.288-10.736-1.633 1.00 0.00 ATOM 650 CB SER 159 3.248-11.273-1.285 1.00 0.00 ATOM 651 1HB SER 159 3.282-12.346-1.417 1.00 0.00 ATOM 652 2HB SER 159 2.283-10.903-1.600 1.00 0.00

ATOM 653 QB SER 159 2.783-11.624-1.509 1.00 0.00 ATOM 654 OG SER 159 3.432-10.971 0.097 1.00 0.00 ATOM 655 HG SER 159 4.375-10.863 0.270 1.00 0.00 ATOM 656 C SER 159 4.433-11.350-3.487 1.00 0.00 ATOM 657 O SER 159 5.138-12.349-3.595 1.00 0.00 ATOM 658 N GLU 160 3.730-10.844-4.504 1.00 0.00 ATOM 659 H GLU 160 3.181-10.041-4.360 1.00 0.00 ATOM 660 CA GLU 160 3.761-11.453-5.836 1.00 0.00 ATOM 661 HA GLU 160 3.515-12.499-5.730 1.00 0.00 ATOM 662 CB GLU 160 2.742-10.784-6.769 1.00 0.00 ATOM 663 1HB GLU 160 3.197-9.914-7.218 1.00 0.00 ATOM 664 2HB GLU 160 1.886-10.472-6.187 1.00 0.00 ATOM 665 QB GLU 160 2.542-10.193-6.703 1.00 0.00 ATOM 666 CG GLU 160 2.246-11.692-7.887 1.00 0.00 ATOM 667 1HG GLU 160 2.859-12.581-7. 911 1.00 0.00 ATOM 668 2HG GLU 160 2.336-11.169-8.827 1.00 0. 00 ATOM 669 QG GLU 160 2.598-11.875-8.369 1.00 0.00 ATOM 670 CD GLU 160 0.803-12.107-7.705 1.00 0.00 ATOM 671 OE1 GLU 160-0. 009-11. 834-8.611 1.00 0. 00 ATOM 672 OE2 GLU 160 0.487-12.706-6.657 1.00 0.00 ATOM 673 C GLU 160 5.166-11.331-6.414 1.00 0.00 ATOM 674 O GLU 160 5.593-12.125-7.254 1.00 0.00 ATOM 675 N LYS+ 161 5.892-10.339-5.919 1.00 0.00 ATOM 676 H LYS+ 161 5.501-9.765-5.232 1.00 0.00 ATOM 677 CA LYS+ 161 7.259-10.111-6.328 1.00 0.00 ATOM 678 HA LYS+ 161 7.415-10.627-7.265 1.00 0.00 ATOM 679 CB LYS+ 161 7.537-8.611-6. 511 1.00 0.00 ATOM 680 1HB LYS+ 161 7.908-8.212-5.579 1.00 0.00 ATOM 681 2HB LYS+ 161 6.611-8.115-6.758 1.00 0.00 ATOM 682 QB LYS+ 161 7.260-8.163-6.169 1.00 0.00 ATOM 683 CG LYS+ 161 8.557-8.309-7.604 1.00 0.00 ATOM 684 1HG LYS+ 161 8.072-7.735-8.381 1.00 0.00 ATOM 685 2HG LYS+ 161 8.911-9.243-8.013 1.00 0.00 ATOM 686 QG LYS+ 161 8.492-8.489-8.197 1.00 0.00 ATOM 687 CD LYS+ 161 9.747-7.519-7.071 1.00 0.00 ATOM 688 1HD LYS+ 161 9.827-7.684-6.005 1.00 0.00 ATOM 689 2HD LYS+ 161 9.580-6.468-7.259 1.00 0.00 ATOM 690 QD LYS+ 161 9.704-7.076-6.632 1.00 0.00 ATOM 691 CE LYS+ 161 11.060-7.933-7.735 1.00 0.00 ATOM 692 1HE LYS+ 161 11.601-8.584-7.060 1.00 0.00 ATOM 693 2HE LYS+ 161 11.647-7.046-7.922 1.00 0.00 ATOM 694 QE LYS+ 161 11.624-7.815-7.491 1.00 0.00 ATOM 695 NZ LYS+ 161 10.846-8.647-9.028 1.00 0.00 ATOM 696 1HZ LYS+ 161 11.407-8.197-9.781 1.00 0.00 ATOM 697 2HZ LYS+ 161 9.842-8.616-9.294 1.00 0.00 ATOM 698 3HZ LYS+ 161 11.140-9.642-8.939 1.00 0.00 ATOM 699 QZ LYS+ 161 10.797-8.818-9.338 1.00 0.00 ATOM 700 C LYS+ 161 8.179-10.707-5.269 1.00 0.00 ATOM 701 O LYS+ 161 7.939-11.803-4.776 1.00 0.00 ATOM 702 N SER 162 9.227-9.990-4.919 1.00 0.00 ATOM 703 H SER 162 9.377-9.126-5.338 1.00 0.00 ATOM 704 CA SER 162 10.159-10.469-3.919 1.00 0.00 ATOM 705 HA SER 162 9.843-11.455-3.618 1.00 0.00 ATOM 706 CB SER 162 11.564-10.560-4.519 1.00 0.00 ATOM 707 1HB SER 162 12.015-11.499-4.228 1.00 0.00 ATOM 708 2HB SER 162 12.165-9.743-4.145 1.00 0.00 ATOM 709 QB SER 162 12.090-10.621-4.187 1.00 0.00 ATOM 710 OG SER 162 11. 519-10. 489-5.943 1.00 0.00 ATOM 711 HG SER 162 11. 510-11. 384-6.299 1.00 0.00 ATOM 712 C SER 162 10.171-9.561-2.691 1.00 0.00 ATOM 713 O SER 162 11.235-9.162-2.233 1.00 0.00 ATOM 714 N THR 163 8.993-9.219-2.159 1.00 0. 00 ATOM 715 H THR 163 8.158-9.550-2.563 1.00 0.00 ATOM 716 CA THR 163 8.928-8.360-0.978 1.00 0.00 ATOM 717 HA THR 163 9.837-8.517-0.411 1.00 0.00 ATOM 718 CB THR 163 8.847-6.882-1.363 1.00 0.00 ATOM 719 HB THR 163 8.635-6.316-0.460 1.00 0.00 ATOM 720 QG2 THR 163 10. 418-6. 188-2.110 1.00 0.00 ATOM 721 OG1 THR 163 7.807-6.656-2.301 1.00 0.00 ATOM 722 1HG THR 163 7.497-7.507-2.648 1.00 0.00 ATOM 723 CG2 THR 163 10. 115-6. 321-1. 967 1.00 0.00 ATOM 724 1HG2 THR 163 10.467-5.496-1.366 1.00 0.00

ATOM 725 2HG2 THR 163 9.915-5.977-2.970 1.00 0.00 ATOM 726 3HG2 THR 163 10.872-7.093-1.995 1.00 0.00 ATOM 727 C THR 163 7.737-8.711-0.080 1.00 0.00 ATOM 728 O THR 163 6.777-9.350-0.506 1.00 0.00 ATOM 729 N ASN 164 7.806-8.263 1.165 1.00 0.00 ATOM 730 H ASN 164 8.602-7.752 1.436 1.00 0.00 ATOM 731 CA ASN 164 6.739-8.496 2.146 1.00 0.00 ATOM 732 HA ASN 164 5.895-8. 924 1.620 1.00 0.00 ATOM 733 CB ASN 164 7.203-9.469 3.240 1.00 0.00 ATOM 734 1HB ASN 164 6. 996-10.479 2.922 1.00 0.00 ATOM 735 2HB ASN 164 6.657-9.264 4.149 1.00 0.00 ATOM 736 QB ASN 164 6.827-9.871 3.535 1.00 0.00 ATOM 737 CG ASN 164 8.687-9. 356 3.540 1.00 0.00 ATOM 738 OD1 ASN 164 9.346-10. 349 3.817 1.00 0.00 ATOM 739 ND2 ASN 164 9.209-8.137 3.508 1.00 0.00 ATOM 740 1HD2 ASN 164 8.612-7.386 3.316 1.00 0.00 ATOM 741 2HD2 ASN 164 10.173-8.044 3.619 1.00 0.00 ATOM 742 QD2 ASN 164 9.393-7.715 3.467 1.00 0.00 ATOM 743 C ASN 164 6.309-7.180 2.795 1.00 0.00 ATOM 744 O ASN 164 7.152-6.385 3.203 1.00 0.00 ATOM 745 N LEU 165 5.002-6. 952 2.881 1.00 0.00 ATOM 746 H LEU 165 4.380-7.621 2.535 1.00 0. 00 ATOM 747 CA LEU 165 4.468-5.722 3.477 1.00 0.00 ATOM 748 HA LEU 165 4.944-4. 876 3.000 1.00 0.00 ATOM 749 CB LEU 165 2.959-5. 628 3.264 1.00 0.00 ATOM 750 1HB LEU 165 2.485-5. 512 4.227 1.00 0.00 ATOM 751 2HB LEU 165 2.616-6.549 2.819 1.00 0.00 ATOM 752 QB LEU 165 2.551-6.030 3.523 1.00 0.00 ATOM 753 CG LEU 165 2.507-4. 476 2.391 1.00 0.00 ATOM 754 HG LEU 165 2.988-3.566 2.720 1.00 0. 00 ATOM 755 QD1 LEU 165 2.999-4.787 0.614 1.00 0.00 ATOM 756 QD2 LEU 165 0.650-4.245 2.540 1.00 0.00 ATOM 757 CD1 LEU 165 2.905-4.728 0.957 1.00 0.00 ATOM 758 1HD1 LEU 165 3.269-5.739 0.855 1.00 0.00 ATOM 759 2HD1 LEU 165 3.682-4.034 0.671 1.00 0.00 ATOM 760 3HD1 LEU 165 2.046-4. 589 0.316 1.00 0.00 ATOM 761 CD2 LEU 165 1.007-4.290 2.512 1.00 0.00 ATOM 762 1HD2 LEU 165 0.501-5. 064 1.953 1.00 0.00 ATOM 763 2HD2 LEU 165 0.732-3. 323 2.117 1.00 0.00 ATOM 764 3HD2 LEU 165 0.717-4.349 3.551 1.00 0.00 ATOM 765 QQD LEU 165 1.825-4.516 1.577 1.00 0.00 ATOM 766 C LEU 165 4.751-5.651 4.964 1.00 0. 00 ATOM 767 O LEU 165 4.412-6.564 5.715 1.00 0.00 ATOM 768 N HIS+ 166 5.354-4. 552 5.375 1.00 0.00 ATOM 769 H HIS+ 166 5.587-3. 859 4.720 1.00 0.00 ATOM 770 CA HIS+ 166 5.672-4. 329 6.770 1.00 0.00 ATOM 771 HA HIS+ 166 5.331-5.186 7.331 1.00 0. 00 ATOM 772 CB HIS+ 166 7.189-4. 183 6.944 1.00 0.00 ATOM 773 1HB HIS+ 166 7.530-3. 347 6.349 1.00 0.00 ATOM 774 2HB HIS+ 166 7.673-5. 083 6.598 1.00 0.00 ATOM 775 QB HIS+ 166 7.602-4.215 6.473 1.00 0. 00 ATOM 776 CG HIS+ 166 7.623-3.944 8.357 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.551-4.901 9.347 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.132-2.839 8.940 1.00 0.00 ATOM 779 1HD HIS+ 166 7.216-5. 817 9.237 1.00 0.00 ATOM 780 CE1 HIS+ 166 7.999-4.388 10.481 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.358-3. 134 10.259 1.00 0.00 ATOM 782 2HD HIS+ 166 8.309-1. 884 8.456 1.00 0.00 ATOM 783 1HE HIS+ 166 8.061-4. 904 11.428 1.00 0.00 ATOM 784 2HE HIS+ 166 8.532-2.468 10.957 1.00 0.00 ATOM 785 C HIS+ 166 4.947-3. 082 7.279 1.00 0.00 ATOM 786 O HIS+ 166 4.267-3.126 8.304 1.00 0.00 ATOM 787 N ASP 167 5.092-1. 975 6.551 1. 00 0.00 ATOM 788 H ASP 167 5.644-2.006 5.737 1.00 0.00 ATOM 789 CA ASP 167 4.450-0.715 6.938 1.00 0.00 ATOM 790 HA ASP 167 3.951-0. 882 7.882 1.00 0.00 ATOM 791 CB ASP 167 5.483 0.404 7.120 1.00 0.00 ATOM 792 1HB ASP 167 5.103 1.118 7.836 1.00 0.00 ATOM 793 2HB ASP 167 5.630 0.902 6.173 1.00 0.00 ATOM 794 QB ASP 167 5.367 1.010 7.004 1.00 0.00 ATOM 795 CG ASP 167 6.829-0.090 7.608 1.00 0.00 ATOM 796 OD1 ASP 167 7.629-0. 567 6.773 1.00 0.00

ATOM 797 OD2 ASP 167 7.090 0.006 8.825 1.00 0.00 ATOM 798 C ASP 167 3.411-0.279 5.909 1.00 0.00 ATOM 799 O ASP 167 3.702 0.498 5.005 1. 00 0.00 ATOM 800 N TYR 168 2.201-0.791 6.049 1.00 0.00 ATOM 801 H TYR 168 2.033-1.408 6.792 1.00 0.00 ATOM 802 CA TYR 168 1.103-0.462 5.140 1.00 0.00 ATOM 803 HA TYR 168 1.525-0.179 4.180 1.00 0.00 ATOM 804 CB TYR 168 0.206-1.687 4.954 1.00 0.00 ATOM 805 1HB TYR 168 0.573-2.275 4.127 1.00 0.00 ATOM 806 2HB TYR 168-0.802-1.359 4.743 1.00 0. 00 ATOM 807 QB TYR 168-0.114-1.817 4.435 1.00 0.00 ATOM 808 QD TYR 168 0.162-2.671 6.320 1.00 0.00 ATOM 809 QE TYR 168 0.114-4.085 8.326 1.00 0.00 ATOM 810 QR TYR 168 0.138-3.378 7.323 1.00 0.00 ATOM 811 CG TYR 168 0.164-2.572 6.179 1.00 0.00 ATOM 812 CD1 TYR 168 0.999-3.676 6.293 1.00 0.00 ATOM 813 1HD TYR 168 1.676-3.908 5.484 1.00 0.00 ATOM 814 CE1 TYR 168 0.975-4.473 7.419 1.00 0.00 ATOM 815 1HE TYR 168 1.634-5.326 7.489 1.00 0.00 ATOM 816 CZ TYR 168 0.110-4.172 8.448 1.00 0.00 ATOM 817 CE2 TYR 168-0.729-3.082 8.358 1.00 0.00 ATOM 818 2HE TYR 168-1.407-2.844 9.164 1.00 0.00 ATOM 819 CD2 TYR 168-0.697-2.290 7.229 1.00 0.00 ATOM 820 2HD TYR 168-1.352-1.434 7.156 1.00 0.00 ATOM 821 OH TYR 168 0.081-4.964 9.570 1.00 0.00 ATOM 822 HH TYR 168 0.829-4.747 10.135 1.00 0.00 ATOM 823 C TYR 168 0.271 0.702 5.672 1.00 0.00 ATOM 824 O TYR 168 0.098 0.856 6.881 1.00 0.00 ATOM 825 N GLY 169-0.265 1.491 4.761 1.00 0.00 ATOM 826 H GLY 169-0.109 1.304 3.811 1.00 0.00 ATOM 827 CA GLY 169-1.097 2.613 5.130 1.00 0.00 ATOM 828 1HA GLY 169-0.498 3.513 5.151 1.00 0.00 ATOM 829 2HA GLY 169-1.517 2.438 6.109 1.00 0.00 ATOM 830 QA GLY 169-1.007 2.976 5.630 1.00 0.00 ATOM 831 C GLY 169-2.208 2.784 4.128 1.00 0.00 ATOM 832 O GLY 169-2.098 2.295 3.005 1.00 0.00 ATOM 833 N MET 170-3.279 3.448 4.513 1.00 0.00 ATOM 834 H MET 170-3.323 3.810 5.424 1.00 0.00 ATOM 835 CA MET 170-4.402 3.646 3.606 1.00 0.00 ATOM 836 HA MET 170-4.029 3.555 2.590 1.00 0.00 ATOM 837 CB MET 170-5.480 2.584 3.845 1.00 0.00 ATOM 838 1HB MET 170-6.380 2.881 3.325 1.00 0.00 ATOM 839 2HB MET 170-5.688 2.531 4.903 1.00 0.00 ATOM 840 QB MET 170-6.034 2.706 4.114 1.00 0.00 ATOM 841 CG MET 170-5.088 1.195 3.364 1.00 0.00 ATOM 842 1HG MET 170-4.333 1.298 2.600 1.00 0.00 ATOM 843 2HG MET 170-5.958 0.715 2.943 1.00 0.00 ATOM 844 QG MET 170-5.145 1.007 2.771 1.00 0.00 ATOM 845 SD MET 170-4.437 0.158 4.688 1.00 0.00 ATOM 846 QE MET 170-3.226-1.230 3.583 1.00 0.00 ATOM 847 CE MET 170-3.429-0.998 3.768 1.00 0.00 ATOM 848 1HE MET 170-2.871-0.465 3.009 1.00 0.00 ATOM 849 2HE MET 170-4.066-1.735 3.298 1.00 0.00 ATOM 850 3HE MET 170-2.742-1.491 4.442 1.00 0.00 ATOM 851 C MET 170-4.997 5.034 3.789 1.00 0.00 ATOM 852 O MET 170-5.525 5.356 4.853 1.00 0.00 ATOM 853 N LEU 171-4.920 5.849 2.749 1.00 0.00 ATOM 854 H LEU 171-4.497 5.532 1.920 1.00 0.00 ATOM 855 CA LEU 171-5.467 7.200 2.812 1.00 0.00 ATOM 856 HA LEU 171-5.857 7.339 3.810 1.00 0.00 ATOM 857 CB LEU 171-4.400 8.270 2.551 1.00 0. 00 ATOM 858 1HB LEU 171-4.346 8.905 3.423 1.00 0.00 ATOM 859 2HB LEU 171-4.725 8.871 1.715 1.00 0.00 ATOM 860 QB LEU 171-4.535 8.888 2.569 1.00 0.00 ATOM 861 CG LEU 171-2.991 7.767 2.248 1.00 0.00 ATOM 862 HG LEU 171-2.789 6.884 2.837 1.00 0.00 ATOM 863 QD1 LEU 171-2.816 7.319 0.429 1.00 0.00 ATOM 864 QD2 LEU 171-1.735 9.083 2.714 1.00 0.00 ATOM 865 CD1 LEU 171-2.851 7.404 0.777 1.00 0.00 ATOM 866 1HD1 LEU 171-2. 224 6.529 0.681 1.00 0.00 ATOM 867 2HD1 LEU 171-2.400 8.230 0.243 1.00 0.00 ATOM 868 3HD1 LEU 171-3.825 7.196 0.362 1.00 0.00

ATOM 869 CD2 LEU 171-1. 977 8.831 2.626 1.00 0.00 ATOM 870 1HD2 LEU 171-1.157 8.372 3.162 1.00 0.00 ATOM 871 2HD2 LEU 171-2.448 9.573 3.253 1.00 0.00 ATOM 872 3HD2 LEU 171-1.601 9.303 1.728 1.00 0.00 ATOM 873 QQD LEU 171-2.276 8.201 1.571 1.00 0.00 ATOM 874 C LEU 171-6.607 7.381 1.825 1.00 0.00 ATOM 875 O LEU 171-7.187 6.404 1.348 1.00 0.00 ATOM 876 N LEU 172-6.911 8.648 1.529 1.00 0.00 ATOM 877 H LEU 172-6.394 9.363 1.951 1.00 0.00 ATOM 878 CA LEU 172-7.978 9.017 0.600 1.00 0.00 ATOM 879 HA LEU 172-8. 160 10.076 0.712 1.00 0.00 ATOM 880 CB LEU 172-7.548 8.740-0.844 1.00 0.00 ATOM 881 1HB LEU 172-8.409 8.378-1.387 1.00 0.00 ATOM 882 2HB LEU 172-6.802 7.958-0.830 1.00 0.00 ATOM 883 QB LEU 172-7.605 8.168-1.109 1.00 0. 00 ATOM 884 CG LEU 172-6.973 9.941-1.603 1.00 0.00 ATOM 885 HG LEU 172-6. 661 9.618-2.584 1.00 0.00 ATOM 886 QD1 LEU 172-8.274 11.280-1.823 1.00 0.00 ATOM 887 QD2 LEU 172-5.465 10.639-0.720 1.00 0.00 ATOM 888 CD1 LEU 172-8.026 11.023-1.780 1.00 0.00 ATOM 889 1AD1 LEU 172-7. 875 11.796-1.041 1.00 0.00 ATOM 890 2HD1 LEU 172-9. 009 10.594-1.658 1.00 0.00 ATOM 891 3HD1 LEU 172-7.939 11.450-2.769 1.00 0.00 ATOM 892 CD2 LEU 172-5.755 10.505-0.888 1.00 0.00 ATOM 893 1HD2 LEU 172-5.946 11.530-0.607 1.00 0.00 ATOM 894 2HD2 LEU 172-4.899 10.466-1.548 1.00 0.00 ATOM 895 3HD2 LEU 172-5.552 9.920-0.004 1.00 0.00 ATOM 896 QQD LEU 172-6.870 10.960-1.271 1.00 0.00 ATOM 897 C LEU 172-9.267 8.264 0.914 1.00 0.00 ATOM 898 O LEU 172-9.688 7.409 0.145 1.00 0.00 ATOM 899 N PRO 173-9.910 8.559 2.055 1.00 0.00 ATOM 900 CD PRO 173-9.490 9.558 3.052 1.00 0.00 ATOM 901 CA PRO 173-11.145 7.880 2.449 1.00 0.00 ATOM 902 HA PRO 173-10.966 6.828 2.622 1.00 0.00 ATOM 903 CB PRO 173-11.545 8.556 3.768 1.00 0.00 ATOM 904 1HB PRO 173-11.308 7.903 4.596 1.00 0.00 ATOM 905 2HB PRO 173-12.606 8.760 3.760 1.00 0.00 ATOM 906 QB PRO 173-11.957 8.332 4.178 1.00 0.00 ATOM 907 CG PRO 173-10.751 9.819 3.827 1.00 0.00 ATOM 908 1HG PRO 173-10.517 10.057 4.855 1.00 0.00 ATOM 909 2HG PRO 173-11.309 10.625 3.373 1.00 0.00 ATOM 910 QG PRO 173-10.913 10.341 4.114 1.00 0.00 ATOM 911 1HD PRO 173-8. 724 9.158 3.700 1.00 0.00 ATOM 912 2HD PRO 173-9.148 10.464 2.573 1.00 0.00 ATOM 913 QD PRO 173-8.936 9.811 3.136 1.00 0.00 ATOM 914 C PRO 173-12.256 8.030 1.413 1.00 0.00 ATOM 915 O PRO 173-12.377 9.059 0.746 1.00 0.00 ATOM 916 N CYS 174-13.063 6.993 1.290 1.00 0.00 ATOM 917 H CYS 174-12.911 6. 204 1.856 1.00 0.00 ATOM 918 CA CYS 174-14.172 6.987 0.349 1.00 0.00 ATOM 919 HA CYS 174-14.159 7.925-0.187 1.00 0.00 ATOM 920 CB CYS 174-14.024 5.836-0.645 1.00 0.00 ATOM 921 1HB CYS 174-14.563 4.979-0.270 1.00 0.00 ATOM 922 2HB CYS 174-12.978 5.584-0.742 1.00 0.00 ATOM 923 QB CYS 174-13.770 5.282-0.506 1.00 0.00 ATOM 924 SG CYS 174-14.660 6.204-2.312 1.00 0.00 ATOM 925 C CYS 174-15. 489 6.865 1.099 1.00 0.00 ATOM 926 O CYS 174-16.544 7.239 0.595 1.00 0.00 ATOM 927 N GLY 175-15.412 6.340 2.312 1.00 0.00 ATOM 928 H GLY 175-14.537 6.064 2.662 1.00 0.00 ATOM 929 CA GLY 175-16.592 6.177 3.134 1.00 0.00 ATOM 930 1HA GLY 175-17.111 5.280 2.834 1.00 0.00 ATOM 931 2HA GLY 175-17.243 7.028 2.989 1.00 0.00 ATOM 932 QA GLY 175-17.177 6.154 2.911 1.00 0.00 ATOM 933 C GLY 175-16.226 6.071 4.596 1.00 0.00 ATOM 934 O GLY 175-15. 191 6.589 5.005 1.00 0.00 ATOM 935 N ILE 176-17. 059 5.392 5.380 1.00 0.00 ATOM 936 H ILE 176-17.864 4.992 4.995 1.00 0.00 ATOM 937 CA ILE 176-16.787 5.219 6.803 1.00 0.00 ATOM 938 HA ILE 176-16.613 6.199 7.227 1.00 0.00 ATOM 939 CB ILE 176-17.995 4.575 7.540 1.00 0.00 ATOM 940 HB ILE 176-18.713 5.358 7.741 1.00 0.00

ATOM 941 QG2 ILE 176-18.842 3.283 6.460 1.00 0.00 ATOM 942 CG2 ILE 176-18.680 3.531 6.664 1.00 0.00 ATOM 943 1HG2 ILE 176-17. 983 3.165 5.927 1.00 0.00 ATOM 944 2HG2 ILE 176-19.531 3.975 6.169 1.00 0.00 ATOM 945 3HG2 ILE 176-19.013 2.709 7.283 1.00 0.00 ATOM 946 CG1 ILE 176-17.563 3.952 8.873 1.00 0. 00 ATOM 947 1HG1 ILE 176-17.185 4.729 9.521 1.00 0. 00 ATOM 948 2HG1 ILE 176-16.779 3.231 8.687 1.00 0.00 ATOM 949 QG1 ILE 176-16. 982 3.980 9.104 1.00 0.00 ATOM 950 QD1 ILE 176-18.948 3.070 9.773 1.00 0.00 ATOM 951 CD1 ILE 176-18.682 3.239 9.600 1.00 0.00 ATOM 952 1HD1 ILE 176-19.484 3.029 8.908 1.00 0.00 ATOM 953 2HD1 ILE 176-19.050 3.866 10.399 1.00 0.00 ATOM 954 3HD1 ILE 176-18.310 2.313 10.011 1.00 0.00 ATOM 955 C ILE 176-15.522 4.373 6.997 1.00 0.00 ATOM 956 O ILE 176-14.568 4.809 7.638 1.00 0.00 ATOM 957 N ASP 177-15. 517 3.178 6.412 1.00 0.00 ATOM 958 H ASP 177-16.299 2.898 5.900 1.00 0.00 ATOM 959 CA ASP 177-14.366 2.287 6.492 1.00 0.00 ATOM 960 HA ASP 177-13.569 2.820 6.992 1.00 0.00 ATOM 961 CB ASP 177-14.695 1.022 7.291 1.00 0.00 ATOM 962 1HB ASP 177-15.274 0.352 6.673 1.00 0.00 ATOM 963 2HB ASP 177-15.271 1.292 8.162 1.00 0.00 ATOM 964 QB ASP 177-15.272 0.822 7.417 1.00 0.00 ATOM 965 CG ASP 177-13.446 0.289 7.751 1.00 0.00 ATOM 966 OD1 ASP 177-12.329 0.811 7.534 1.00 0.00 ATOM 967 OD2 ASP 177-13.583-0. 814 8.317 1.00 0.00 ATOM 968 C ASP 177-13.900 1.912 5.089 1.00 0.00 ATOM 969 O ASP 177-13.608 0.753 4.790 1.00 0.00 ATOM 970 N LYS+ 178-13.832 2.906 4.222 1.00 0.00 ATOM 971 H LYS+ 178-14.071 3.811 4.514 1.00 0.00 ATOM 972 CA LYS+ 178-13.391 2.691 2.854 1.00 0.00 ATOM 973 HA LYS+ 178-12.909 1.724 2.809 1.00 0.00 ATOM 974 CB LYS+ 178-14.562 2.717 1.870 1.00 0. 00 ATOM 975 1HB LYS+ 178-14.181 2.531 0.877 1.00 0.00 ATOM 976 2HB LYS+ 178-15.007 3.698 1.894 1.00 0.00 ATOM 977 QB LYS+ 178-14.594 3.115 1.385 1.00 0.00 ATOM 978 CG LYS+ 178-15.644 1.685 2.174 1.00 0.00 ATOM 979 1HG LYS+ 178-16.539 2.201 2.491 1.00 0.00 ATOM 980 2HG LYS+ 178-15.297 1.043 2.972 1.00 0. 00 ATOM 981 QG LYS+ 178-15.918 1.622 2.731 1.00 0.00 ATOM 982 CD LYS+ 178-15.973 0.826 0.960 1.00 0.00 ATOM 983 1HD LYS+ 178-15.296 1.081 0.157 1.00 0.00 ATOM 984 2HD LYS+ 178-16.988 1.030 0.655 1.00 0. 00 ATOM 985 QD LYS+ 178-16.142 1.056 0.406 1.00 0.00 ATOM 986 CE LYS+ 178-15.839-0. 665 1.264 1.00 0.00 ATOM 987 1HE LYS+ 178-16.595-0.941 1.985 1.00 0.00 ATOM 988 2HE LYS+ 178-14.861-0. 849 1.686 1.00 0.00 ATOM 989 QE LYS+ 178-15.728-0. 895 1.835 1.00 0.00 ATOM 990 NZ LYS+ 178-16. 005-1.507 0.042 1.00 0.00 ATOM 991 1HZ LYS+ 178-15.193-2.169-0.059 1.00 0.00 ATOM 992 2HZ LYS+ 178-16.047-0.913-0.811 1.00 0.00 ATOM 993 3HZ LYS+ 178-16.877-2.068 0.103 1.00 0.00 ATOM 994 QZ LYS+ 178-16.039-1.716-0.256 1.00 0.00 ATOM 995 C LYS+ 178-12. 375 3.742 2.486 1.00 0.00 ATOM 996 O LYS+ 178-12.507 4.901 2.867 1.00 0.00 ATOM 997 N PHE 179-11.360 3.329 1.757 1.00 0.00 ATOM 998 H PHE 179-11.314 2.388 1.488 1.00 0.00 ATOM 999 CA PHE 179-10.305 4.231 1.353 1.00 0.00 ATOM 1000 HA PHE 179-10.620 5.238 1.579 1.00 0.00 ATOM 1001 CB PHE 179-9.018 3.927 2.122 1.00 0.00 ATOM 1002 1HB PHE 179-8.304 4.689 1.896 1.00 0.00 ATOM 1003 2HB PHE 179-8.624 2.978 1. 797 1.00 0.00 ATOM 1004 QB PHE 179-8.464 3.834 1.846 1.00 0.00 ATOM 1005 QD PHE 179-9.216 3.874 3.782 1.00 0.00 ATOM 1006 QE PHE 179-9.520 3.810 6.222 1.00 0.00 ATOM 1007 QR PHE 179-9.429 3.829 5.491 1.00 0.00 ATOM 1008 CG PHE 179-9.195 3.880 3.615 1.00 0.00 ATOM 1009 CD1 PHE 179-8.926 4.996 4.391 1.00 0.00 ATOM 1010 1HD PHE 179-8.581 5.901 3.914 1.00 0.00 ATOM 1011 CE1 PHE 179-9.095 4.962 5.762 1.00 0.00 ATOM 1012 1HE PHE 179-8.882 5.839 6.355 1.00 0.00

ATOM 1013 CZ PHE 179-9.538 3.805 6.373 1.00 0.00 ATOM 1014 HZ PHE 179-9. 673 3.777 7.445 1.00 0.00 ATOM 1015 CE2 PHE 179-9.809 2.685 5.613 1.00 0.00 ATOM 1016 2HE PHE 179-10.159 1.780 6.089 1.00 0.00 ATOM 1017 CD2 PHE 179-9. 638 2.724 4.243 1.00 0.00 ATOM 1018 2HD PHE 179-9.852 1.847 3.650 1.00 0.00 ATOM 1019 C PHE 179-10.042 4.114-0.130 1.00 0.00 ATOM 1020 O PHE 179-10.712 3.357-0.830 1.00 0.00 ATOM 1021 N ARG+ 180-9.057 4.862-0.593 1.00 0.00 ATOM 1022 H ARG+ 180-8.568 5.440 0.034 1.00 0.00 ATOM 1023 CA ARG+ 180-8.671 4.858-1.996 1.00 0. 00 ATOM 1024 HA ARG+ 180-9.065 3.961-2.456 1.00 0.00 ATOM 1025 CB ARG+ 180-9.257 6.080-2.712 1.00 0.00 ATOM 1026 1HB ARG+ 180-9.012 6.014-3.763 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.809 6.973-2.303 1.00 0.00 ATOM 1028 QB ARG+ 180-8.910 6.494-3.033 1.00 0.00 ATOM 1029 CG ARG+ 180-10.767 6.196-2.581 1.00 0.00 ATOM 1030 1HG ARG+ 180-11.046 5.950-1.566 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.231 5.497-3.262 1.00 0.00 ATOM 1032 QG ARG+ 180-11.138 5.724-2.414 1.00 0.00 ATOM 1033 CD ARG+ 180-11.257 7.597-2.901 1.00 0.00 ATOM 1034 1HD ARG+ 180-10.420 8.279-2.849 1.00 0.00 ATOM 1035 2HD ARG+ 180-11.997 7.880-2.168 1.00 0.00 ATOM 1036 QD ARG+ 180-11.208 8.080-2.509 1.00 0.00 ATOM 1037 NE ARG+ 180-11.852 7.672-4.234 1.00 0.00 ATOM 1038 HE ARG+ 180-11.450 7.115-4.941 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.887 8.450-4.545 1.00 0.00 ATOM 1040 NH1 ARG+ 180-13.456 9.205-3.609 1.00 0. 00 ATOM 1041 1HH1 ARG+ 180-13.105 9.188-2.672 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-14.235 9.790-3.837 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.670 9.489-3.255 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.343 8.476-5.792 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.902 7.909-6.500 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-14.120 9.054-6.034 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13.511 8.482-6.267 1.00 0.00 ATOM 1048 C ARG+ 180-7.151 4.859-2.136 1.00 0.00 ATOM 1049 O ARG+ 180-6.617 4.548-3.190 1.00 0.00 ATOM 1050 N GLY 181-6.450 5.217-1.072 1.00 0.00 ATOM 1051 H GLY 181-6.913 5.457-0.239 1.00 0.00 ATOM 1052 CA GLY 181-5.001 5.258-1.141 1.00 0.00 ATOM 1053 1HA GLY 181-4.666 6.227-0.803 1.00 0.00 ATOM 1054 2HA GLY 181-4.701 5.129-2.169 1.00 0.00 ATOM 1055 QA GLY 181-4.683 5.678-1.486 1.00 0.00 ATOM 1056 C GLY 181-4.334 4.192-0.305 1.00 0.00 ATOM 1057 O GLY 181-4.896 3.730 0. 686 1.00 0.00 ATOM 1058 N VAL 182-3.124 3.811-0.704 1.00 0.00 ATOM 1059 H VAL 182-2.733 4.231-1.495 1.00 0.00 ATOM 1060 CA VAL 182-2.351 2.801 0.009 1.00 0.00 ATOM 1061 HA VAL 182-2. 705 2.771 1.034 1.00 0.00 ATOM 1062 CB VAL 182-2.495 1.386-0.611 1.00 0.00 ATOM 1063 HB VAL 182-1. 683 1.247-1.311 1. 00 0. 00 ATOM 1064 QG1 VAL 182-2.345 0.068 0.718 1.00 0.00 ATOM 1065 QG2 VAL 182-4.115 1.183-1.547 1.00 0.00 ATOM 1066 CG1 VAL 182-2.374 0.320 0.463 1.00 0.00 ATOM 1067 1HG1 VAL 182-1.496-0. 282 0.276 1.00 0.00 ATOM 1068 2HG1 VAL 182-3.252-0. 309 0.446 1.00 0. 00 ATOM 1069 3HG1 VAL 182-2.287 0.793 1.432 1.00 0.00 ATOM 1070 CG2 VAL 182-3.806 1.222-1.368 1.00 0.00 ATOM 1071 1HG2 VAL 182-4.595 1.736-0.840 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.047 0.172-1.443 1.00 0.00 ATOM 1073 3HG2 VAL 182-3.704 1.639-2.359 1.00 0.00 ATOM 1074 QQG VAL 182-3.230 0. 625-0. 415 1.00 0.00 ATOM 1075 C VAL 182-0.865 3.178 0.009 1.00 0.00 ATOM 1076 O VAL 182-0.291 3.466-1.039 1.00 0.00 ATOM 1077 N GLU 183-0.261 3.167 1.190 1.00 0.00 ATOM 1078 H GLU 183-0.786 2.925 1.982 1.00 0.00 ATOM 1079 CA GLU 183 1.151 3.499 1.369 1.00 0. 00 ATOM 1080 HA GLU 183 1.604 3.647 0.396 1.00 0.00 ATOM 1081 CB GLU 183 1.279 4.782 2.200 1.00 0.00 ATOM 1082 1HB GLU 183 1.819 5.519 1.625 1.00 0.00 ATOM 1083 2HB GLU 183 1.839 4.559 3.098 1.00 0. 00 ATOM 1084 QB GLU 183 1.829 5.039 2.361 1.00 0.00

ATOM 1085 CG GLU 183-0. 058 5.388 2.616 1.00 0.00 ATOM 1086 1HG GLU 183-0.789 4.597 2.696 1.00 0.00 ATOM 1087 2HG GLU 183-0.373 6.091 1.859 1.00 0.00 ATOM 1088 QG GLU 183-0.581 5.344 2.277 1.00 0.00 ATOM 1089 CD GLU 183 0.016 6.113 3.943 1.00 0.00 ATOM 1090 OE1 GLU 183-0. 456 5.550 4.949 1.00 0.00 ATOM 1091 OE2 GLU 183 0.544 7.246 3.972 1.00 0.00 ATOM 1092 C GLU 183 1.845 2.354 2.101 1.00 0.00 ATOM 1093 0 GLU 183 1.869 2.327 3.325 1.00 0.00 ATOM 1094 N PHE 184 2.366 1.386 1.369 1.00 0.00 ATOM 1095 H PHE 184 2.300 1.427 0.396 1.00 0.00 ATOM 1096 CA PHE 184 2.990 0.229 2.005 1.00 0.00 ATOM 1097 HA PHE 184 2.850 0.344 3.067 1.00 0.00 ATOM 1098 CB PHE 184 2.296-1.068 1.568 1.00 0.00 ATOM 1099 1HB PHE 184 1.398-1.204 2.153 1.00 0.00 ATOM 1100 2HB PHE 184 2.961-1.898 1.763 1.00 0.00 ATOM 1101 QB PHE 184 2.180-1.551 1.958 1.00 0.00 ATOM 1102 QD PHE 184 1.870-1.135-0.063 1.00 0.00 ATOM 1103 QE PHE 184 1.230-1.289-2.430 1.00 0.00 ATOM 1104 QR PHE 184 1.421-1.245-1.720 1.00 0.00 ATOM 1105 CG PHE 184 1.915-1.128 0.105 1.00 0.00 ATOM 1106 CD1 PHE 184 2.557-2.008-0.749 1.00 0.00 ATOM 1107 1HD PHE 184 3.348-2.634-0.366 1.00 0.00 ATOM 1108 CE1 PHE 184 2.197-2.099-2.079 1.00 0.00 ATOM 1109 1HE PHE 184 2.708-2.791-2.731 1.00 0.00 ATOM 1110 CZ PHE 184 1.189-1.302-2.576 1.00 0.00 ATOM 1111 HZ PHE 184 0.902-1.378-3.613 1.00 0.00 ATOM 1112 CE2 PHE 184 0.542-0.414-1.742 1.00 0.00 ATOM 1113 2HE PHE 184-0.248 0.213-2.129 1.00 0.00 ATOM 1114 CD2 PHE 184 0.901-0.333-0.410 1.00 0.00 ATOM 1115 2HD PHE 184 0.392 0.364 0.241 1.00 0.00 ATOM 1116 C PHE 184 4.479 0.112 1.735 1.00 0.00 ATOM 1117 0 PHE 184 4.945 0.318 0.620 1.00 0.00 ATOM 1118 N VAL 185 5.214-0.259 2.774 1.00 0.00 ATOM 1119 H VAL 185 4.771-0.428 3.634 1.00 0.00 ATOM 1120 CA VAL 185 6.648-0.448 2.676 1.00 0.00 ATOM 1121 HA VAL 185 6.966-0.109 1.699 1.00 0.00 ATOM 1122 CB VAL 185 7.408 0.362 3.755 1.00 0.00 ATOM 1123 HB VAL 185 7.566-0.278 4.616 1.00 0.00 ATOM 1124 QG1 VAL 185 9.083 0. 916 3.118 1.00 0. 00 ATOM 1125 QG2 VAL 185 6.409 1.855 4.313 1.00 0.00 ATOM 1126 CG1 VAL 185 8.763 0.808 3.239 1.00 0.00 ATOM 1127 1HG1 VAL 185 8.984 0.296 2.316 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.519 0.577 3.974 1.00 0. 00 ATOM 1129 3HG1 VAL 185 8.745 1.874 3.065 1.00 0.00 ATOM 1130 CG2 VAL 185 6.601 1.569 4.205 1.00 0.00 ATOM 1131 1HG2 VAL 185 6.823 1.783 5.241 1.00 0.00 ATOM 1132 2HG2 VAL 185 5.546 1.357 4.101 1.00 0. 00 ATOM 1133 3HG2 VAL 185 6. 858 2.424 3.598 1.00 0.00 ATOM 1134 QQG VAL 185 7.746 1. 385 3.716 1.00 0.00 ATOM 1135 C VAL 185 6.970-1.936 2.815 1.00 0.00 ATOM 1136 O VAL 185 6.839-2.514 3.892 1.00 0.00 ATOM 1137 N CYS 186 7.362-2.563 1.715 1.00 0.00 ATOM 1138 H CYS 186 7.430-2.057 0.873 1.00 0.00 ATOM 1139 CA CYS 186 7.676-3.987 1.725 1.00 0.00 ATOM 1140 HA CYS 186 7.434-4.369 2.708 1.00 0.00 ATOM 1141 CB CYS 186 6.827-4.734 0.689 1.00 0.00 ATOM 1142 1HB CYS 186 5.804-4.766 1.034 1.00 0.00 ATOM 1143 2HB CYS 186 7.198-5.743 0.599 1.00 0.00 ATOM 1144 QB CYS 186 6.501-5.254 0.816 1.00 0.00 ATOM 1145 SG CYS 186 6.825-4.006-0.978 1.00 0.00 ATOM 1146 C CYS 186 9.161-4.217 1.466 1.00 0.00 ATOM 1147 O CYS 186 9.719-3.673 0.524 1.00 0.00 ATOM 1148 N CYS 187 9.803-5.023 2.302 1.00 0.00 ATOM 1149 H CYS 187 9.311-5.442 3.042 1.00 0.00 ATOM 1150 CA CYS 187 11.236-5.292 2.143 1.00 0.00 ATOM 1151 HA CYS 187 11.675-4.442 1.644 1.00 0.00 ATOM 1152 CB CYS 187 11.918-5.469 3.505 1.00 0.00 ATOM 1153 1HB CYS 187 12. 724-6.183 3.402 1.00 0.00 ATOM 1154 2HB CYS 187 11. 198-5. 851 4.214 1.00 0.00 ATOM 1155 QB CYS 187 11.961-6.017 3.808 1.00 0.00 ATOM 1156 SG CYS 187 12.619-3.937 4.198 1.00 0.00

ATOM 1157 C CYS 187 11.481-6.529 1.299 1.00 0.00 ATOM 1158 O CYS 187 10.674-7.453 1.301 1.00 0.00 ATOM 1159 N PRO 188 12.598-6.547 0.549 1.00 0.00 ATOM 1160 CD PRO 188 13.593-5.462 0.473 1.00 0.00 ATOM 1161 CA PRO 188 12.957-7.675-0.320 1.00 0.00 ATOM 1162 HA PRO 188 12.216-7.834-1. 091 1.00 0.00 ATOM 1163 CB PRO 188 14.280-7.243-0.961 1.00 0.00 ATOM 1164 1HB PRO 188 14.286-7.529-2.003 1.00 0.00 ATOM 1165 2HB PRO 188 15.100-7.724-0.448 1.00 0.00 ATOM 1166 QB PRO 188 14.693-7.626-1.226 1.00 0.00 ATOM 1167 CG PRO 188 14. 327-5.762-0.802 1.00 0.00 ATOM 1168 1HG PRO 188 13.835-5.287-1.638 1.00 0.00 ATOM 1169 2HG PRO 188 15.353-5.432-0.731 1.00 0.00 ATOM 1170 QG PRO 188 14.594-5.359-1.185 1.00 0.00 ATOM 1171 1HD PRO 188 13.109-4.499 0.411 1.00 0.00 ATOM 1172 2HD PRO 188 14. 268-5.492 1.317 1.00 0.00 ATOM 1173 QD PRO 188 13.689-4.995 0.864 1.00 0.00 ATOM 1174 C PRO 188 13.155-8.973 0.458 1.00 0.00 ATOM 1175 O PRO 188 13.938-9.022 1.409 1.00 0.00 ATOM 1176 N LEU 189 12.447-10.010 0.035 1.00 0.00 ATOM 1177 H LEU 189 11.849-9.895-0.735 1.00 0.00 ATOM 1178 CA LEU 189 12.533-11.317 0.659 1.00 0.00 ATOM 1179 HA LEU 189 13.436-11.350 1.252 1.00 0.00 ATOM 1180 CB LEU 189 11.320-11.559 1.565 1.00 0.00 ATOM 1181 1HB LEU 189 10.549-12.028 0.970 1.00 0.00 ATOM 1182 2HB LEU 189 10.955-10.602 1.903 1.00 0.00 ATOM 1183 QB LEU 189 10.752-11.315 1.436 1.00 0.00 ATOM 1184 CG LEU 189 11.573-12.439 2.797 1.00 0.00 ATOM 1185 HG LEU 189 10.856-12.182 3.563 1.00 0.00 ATOM 1186 QD1 LEU 189 11.343-14.256 2.379 1.00 0.00 ATOM 1187 QD2 LEU 189 13.297-12.141 3.492 1.00 0.00 ATOM 1188 CD1 LEU 189 11.386-13.909 2.460 1.00 0.00 ATOM 1189 1HD1 LEU 189 11.824-14.514 3.239 1.00 0.00 ATOM 1190 2HD1 LEU 189 11.872-14.126 1.518 1.00 0.00 ATOM 1191 3HD1 LEU 189 10.332-14.129 2.381 1.00 0.00 ATOM 1192 CD2 LEU 189 12.967-12.198 3.360 1.00 0.00 ATOM 1193 1HD2 LEU 189 13.695-12.707 2.744 1.00 0.00 ATOM 1194 2HD2 LEU 189 13.018-12.579 4.368 1.00 0.00 ATOM 1195 3HD2 LEU 189 13.176-11.139 3.363 1.00 0.00 ATOM 1196 QQD LEU 189 12.320-13.199 2.935 1.00 0.00 ATOM 1197 C LEU 189 12.603-12.393-0.421 1.00 0.00 ATOM 1198 OT1 LEU 189 13.329-13.388-0.224 1.00 0.00 ATOM 1199 OT2 LEU 189 11.930-12.223-1.462 1.00 0.00 TER ENDMDL MODEL 9 ATOM 1 N SER 124 11.586 7.547 6. 241 1.00 0.00 ATOM 2 CA SER 124 11.176 8. 915 6.644 1.00 0.00 ATOM 3 HA SER 124 10.138 9.061 6.389 1.00 0. 00 ATOM 4 CB SER 124 11.358 9.038 8.157 1.00 0.00 ATOM 5 1HB SER 124 10.493 9.523 8.585 1.00 0.00 ATOM 6 2HB SER 124 12.241 9.629 8.364 1.00 0.00 ATOM 7 QB SER 124 11.367 9.576 8.475 1.00 0.00 ATOM 8 OG SER 124 11.511 7.756 8.751 1.00 0.00 ATOM 9 HG SER 124 11.678 7.856 9.697 1.00 0.00 ATOM 10 C SER 124 12.025 9.937 5.917 1.00 0.00 ATOM 11 O SER 124 12.757 10.714 6.528 1.00 0.00 ATOM 12 1HT SER 124 12.389 7.596 5.571 1.00 0.00 ATOM 13 2HT SER 124 10.797 7.054 5.782 1.00 0.00 ATOM 14 3HT SER 124 11. 882 7.006 7.079 1.00 0.00 ATOM 15 N ASP 125 11.945 9.881 4.603 1.00 0.00 ATOM 16 H ASP 125 11.363 9.208 4.192 1.00 0.00 ATOM 17 CA ASP 125 12. 721 10.739 3.733 1.00 0. 00 ATOM 18 HA ASP 125 13. 150 11.537 4.319 1.00 0.00 ATOM 19 CB ASP 125 13.836 9.895 3.109 1.00 0.00 ATOM 20 1HB ASP 125 14.751 10.048 3.659 1.00 0.00 ATOM 21 2HB ASP 125 13. 979 10.196 2.081 1.00 0.00 ATOM 22 QB ASP 125 14.365 10.122 2.870 1.00 0.00 ATOM 23 CG ASP 125 13.496 8.413 3.137 1.00 0.00 ATOM 24 OD1 ASP 125 13.685 7.772 4.199 1.00 0.00 ATOM 25 OD2 ASP 125 12.991 7.905 2.120 1.00 0.00 ATOM 26 C ASP 125 11.825 11.314 2.650 1.00 0.00

ATOM 27 O ASP 125 11.541 12.510 2.628 1.00 0.00 ATOM 28 N ALA 126 11.370 10.442 1.764 1.00 0.00 ATOM 29 H ALA 126 11.628 9.497 1.848 1.00 0.00 ATOM 30 CA ALA 126 10.490 10.843 0.681 1.00 0.00 ATOM 31 HA ALA 126 10.289 11.899 0.789 1.00 0.00 ATOM 32 QB ALA 126 11.332 10.566-0.981 1.00 0.00 ATOM 33 CB ALA 126 11.170 10.619-0.664 1.00 0.00 ATOM 34 1HB ALA 126 11.740 9.701-0.631 1.00 0.00 ATOM 35 2HB ALA 126 11.833 11.446-0.873 1.00 0.00 ATOM 36 3HB ALA 126 10.423 10.552-1.440 1.00 0.00 ATOM 37 C ALA 126 9.176 10.078 0.749 1.00 0.00 ATOM 38 O ALA 126 8.888 9.402 1.737 1.00 0.00 ATOM 39 N LEU 127 8.387 10. 185-0.310 1.00 0.00 ATOM 40 H LEU 127 8.676 10.735-1.063 1.00 0.00 ATOM 41 CA LEU 127 7.102 9.506-0.386 1.00 0.00 ATOM 42 HA LEU 127 6.832 9.181 0.605 1.00 0.00 ATOM 43 CB LEU 127 6.040 10.469-0.916 1.00 0. 00 ATOM 44 1HB LEU 127 6.023 10.381-1.992 1.00 0.00 ATOM 45 2HB LEU 127 6.336 11.475-0.658 1.00 0.00 ATOM 46 QB LEU 127 6.179 10.928-1.325 1.00 0.00 ATOM 47 CG LEU 127 4.623 10.234-0.395 1.00 0.00 ATOM 48 HG LEU 127 4.348 9.202-0.565 1.00 0.00 ATOM 49 QD1 LEU 127 4.533 10.561 1.454 1.00 0.00 ATOM 50 QD2 LEU 127 3.396 11.324-1.313 1.00 0.00 ATOM 51 CD1 LEU 127 4.551 10.499 1.100 1.00 0.00 ATOM 52 1HD1 LEU 127 4.191 11.502 1.270 1.00 0.00 ATOM 53 2HD1 LEU 127 5.534 10.390 1.533 1.00 0.00 ATOM 54 3HD1 LEU 127 3.875 9.791 1.557 1.00 0.00 ATOM 55 CD2 LEU 127 3.632 11.116-1.138 1.00 0.00 ATOM 56 1HD2 LEU 127 3.879 11.131-2.189 1.00 0.00 ATOM 57 2HD2 LEU 127 3.675 12.120-0.743 1.00 0.00 ATOM 58 3HD2 LEU 127 2.634 10.721-1.009 1.00 0.00 ATOM 59 QQD LEU 127 3.964 10.942 0.070 1.00 0.00 ATOM 60 C LEU 127 7.203 8.295-1.306 1.00 0.00 ATOM 61 O LEU 127 6.195 7.751-1.756 1.00 0.00 ATOM 62 N LEU 128 8.429 7.886-1.595 1.00 0.00 ATOM 63 H LEU 128 9.191 8.363-1.215 1.00 0.00 ATOM 64 CA LEU 128 8.666 6.753-2.470 1.00 0.00 ATOM 65 HA LEU 128 7.721 6.262-2.639 1.00 0.00 ATOM 66 CB LEU 128 9.230 7.248-3.815 1.00 0.00 ATOM 67 1HB LEU 128 10.309 7.236-3.747 1.00 0.00 ATOM 68 2HB LEU 128 8.913 8.271-3.953 1.00 0.00 ATOM 69 QB LEU 128 9.611 7.753-3.850 1.00 0.00 ATOM 70 CG LEU 128 8.823 6.451-5.070 1.00 0.00 ATOM 71 HG LEU 128 8.415 7.139-5.797 1.00 0.00 ATOM 72 QD1 LEU 128 10.315 5.621-5.855 1.00 0.00 ATOM 73 QD2 LEU 128 7.489 5.181-4.678 1.00 0.00 ATOM 74 CD1 LEU 128 10.029 5.780-5.705 1.00 0.00 ATOM 75 1HD1 LEU 128 9.929 4.708-5.624 1.00 0.00 ATOM 76 2HD1 LEU 128 10.928 6.097-5.196 1.00 0.00 ATOM 77 3HD1 LEU 128 10.088 6.059-6.747 1.00 0.00 ATOM 78 CD2 LEU 128 7.745 5.424-4.753 1.00 0.00 ATOM 79 1HD2 LEU 128 8.102 4.749-3.989 1.00 0.00 ATOM 80 2HD2 LEU 128 7.509 4.864-5.646 1.00 0.00 ATOM 81 3HD2 LEU 128 6. 858 5.930-4.401 1.00 0.00 ATOM 82 QQD LEU 128 8.902 5.401-5.267 1.00 0.00 ATOM 83 C LEU 128 9.626 5.769-1.798 1.00 0.00 ATOM 84 O LEU 128 9.724 5.735-0.574 1.00 0.00 ATOM 85 N VAL 129 10.318 4.975-2.607 1.00 0.00 ATOM 86 H VAL 129 10.182 5.060-3.572 1.00 0.00 ATOM 87 CA VAL 129 11.268 3.977-2.116 1.00 0.00 ATOM 88 HA VAL 129 10.717 3.248-1.545 1.00 0.00 ATOM 89 CB VAL 129 11.944 3.254-3.306 1.00 0.00 ATOM 90 HB VAL 129 12.382 4.004-3.949 1.00 0.00 ATOM 91 QG1 VAL 129 13.323 2.111-2.730 1.00 0.00 ATOM 92 QG2 VAL 129 10.668 2.300-4.305 1.00 0. 00 ATOM 93 CG1 VAL 129 13.058 2.329-2.841 1.00 0.00 ATOM 94 1HG1 VAL 129 13.516 1.856-3.697 1.00 0.00 ATOM 95 2HG1 VAL 129 12.652 1.573-2.185 1.00 0.00 ATOM 96 3HG1 VAL 129 13.803 2.904-2.308 1.00 0.00 ATOM 97 CG2 VAL 129 10.912 2.482-4.115 1.00 0.00 ATOM 98 1HG2 VAL 129 11.011 2.738-5.159 1.00 0.00

ATOM 99 2HG2 VAL 129 9.920 2.740-3.773 1.00 0.00 ATOM 100 3HG2 VAL 129 11.075 1.423-3.985 1.00 0.00 ATOM 101 QQG VAL 129 11.996 2.205-3.518 1.00 0.00 ATOM 102 C VAL 129 12.339 4.603-1.217 1.00 0.00 ATOM 103 O VAL 129 13.028 5.538-1.620 1.00 0.00 ATOM 104 N PRO 130 12.478 4.083 0.023 1.00 0.00 ATOM 105 CD PRO 130 11.677 2.976 0.575 1.00 0.00 ATOM 106 CA PRO 130 13.454 4.577 0.990 1.00 0.00 ATOM 107 HA PRO 130 13.544 5.652 0.942 1.00 0.00 ATOM 108 CB PRO 130 12.832 4.177 2.328 1.00 0.00 ATOM 109 1HB PRO 130 12.192 4.973 2.678 1.00 0.00 ATOM 110 2HB PRO 130 13.615 3.996 3.049 1.00 0.00 ATOM 111 QB PRO 130 12.903 4.484 2.864 1.00 0.00 ATOM 112 CG PRO 130 12.050 2.935 2.039 1.00 0.00 ATOM 113 1HG PRO 130 11.159 2.917 2.650 1.00 0.00 ATOM 114 2HG PRO 130 12.659 2.068 2.243 1.00 0.00 ATOM 115 QG PRO 130 11.909 2.492 2.447 1.00 0.00 ATOM 116 1HD PRO 130 10.621 3.175 0.463 1.00 0.00 ATOM 117 2HD PRO 130 11.937 2.043 0.095 1.00 0. 00 ATOM 118 QD PRO 130 11.279 2.609 0.279 1.00 0.00 ATOM 119 C PRO 130 14.843 3.949 0.808 1.00 0.00 ATOM 120 O PRO 130 15.484 4.134-0.224 1.00 0.00 ATOM 121 N ASP 131 15.304 3.221 1.826 1.00 0.00 ATOM 122 H ASP 131 14.751 3.123 2.623 1.00 0.00 ATOM 123 CA ASP 131 16.622 2.585 1.790 1.00 0.00 ATOM 124 HA ASP 131 17.303 3.270 1.306 1.00 0.00 ATOM 125 CB ASP 131 17.112 2.335 3.223 1.00 0.00 ATOM 126 1HB ASP 131 16.480 1.596 3.690 1.00 0.00 ATOM 127 2HB ASP 131 17.052 3.257 3.781 1.00 0.00 ATOM 128 QB ASP 131 16.766 2.426 3.736 1.00 0.00 ATOM 129 CG ASP 131 18.543 1.843 3.276 1.00 0.00 ATOM 130 OD1 ASP 131 19.431 2.541 2.752 1.00 0.00 ATOM 131 OD2 ASP 131 18.768 0.756 3.845 1.00 0.00 ATOM 132 C ASP 131 16.608 1.271 0.997 1.00 0.00 ATOM 133 O ASP 131 16.612 1.276-0.232 1.00 0.00 ATOM 134 N LYS+ 132 16.598 0.141 1.700 1.00 0.00 ATOM 135 H LYS+ 132 16.607 0.188 2.679 1.00 0.00 ATOM 136 CA LYS+ 132 16.602-1.162 1.038 1.00 0.00 ATOM 137 HA LYS+ 132 16.866-0.994 0.003 1.00 0.00 ATOM 138 CB LYS+ 132 17.654-2. 085 1.668 1.00 0.00 ATOM 139 1HB LYS+ 132 18.631-1. 782 1.315 1.00 0.00 ATOM 140 2HB LYS+ 132 17.465-3.095 1.345 1.00 0.00 ATOM 141 QB LYS+ 132 18.048-2. 439 1.330 1.00 0.00 ATOM 142 CG LYS+ 132 17.674-2.065 3.194 1.00 0.00 ATOM 143 1HG LYS+ 132 17.167-1. 174 3.537 1.00 0.00 ATOM 144 2HG LYS+ 132 18.702-2.040 3.527 1.00 0.00 ATOM 145 QG LYS+ 132 17.934-1. 607 3.532 1.00 0.00 ATOM 146 CD LYS+ 132 16.991-3. 288 3.798 1.00 0.00 ATOM 147 1HD LYS+ 132 15.965-3. 316 3.461 1.00 0.00 ATOM 148 2HD LYS+ 132 17.013-3. 200 4.875 1.00 0.00 ATOM 149 QD LYS+ 132 16.489-3.258 4.168 1.00 0.00 ATOM 150 CE LYS+ 132 17.685-4. 583 3.397 1.00 0.00 ATOM 151 1HE LYS+ 132 17.597-5.290 4.211 1.00 0.00 ATOM 152 2HE LYS+ 132 18.729-4. 375 3.215 1.00 0.00 ATOM 153 QE LYS+ 132 18.163-4. 833 3.713 1.00 0.00 ATOM 154 NZ LYS+ 132 17.087-5. 180 2.167 1.00 0.00 ATOM 155 1HZ LYS+ 132 16.396-4.519 1.748 1.00 0.00 ATOM 156 2HZ LYS+ 132 16.602-6.073 2.396 1.00 0.00 ATOM 157 3HZ LYS+ 132 17.831-5.375 1.467 1.00 0.00 ATOM 158 QZ LYS+ 132 16.943-5.323 1.871 1.00 0.00 ATOM 159 C LYS+ 132 15.226-1. 822 1.084 1.00 0.00 ATOM 160 O LYS+ 132 15.110-3. 047 1.218 1.00 0.00 ATOM 161 N CYS 133 14.192-1.009 0.952 1.00 0.00 ATOM 162 H CYS 133 14.357-0.052 0.830 1.00 0.00 ATOM 163 CA CYS 133 12.819-1.488 0.954 1. 00 0.00 ATOM 164 HA CYS 133 12.834-2.544 0.731 1.00 0.00 ATOM 165 CB CYS 133 12.169-1.265 2.322 1.00 0.00 ATOM 166 1HB CYS 133 11.121-1.520 2.262 1. 00 0. 00 ATOM 167 2HB CYS 133 12.266-0.224 2.595 1.00 0.00 ATOM 168 QB CYS 133 11.693-0.872 2.429 1.00 0.00 ATOM 169 SG CYS 133 12.911-2.261 3.658 1.00 0.00 ATOM 170 C CYS 133 12.049-0.763-0. 142 1.00 0.00

ATOM 171 O CYS 133 12.538 0.219-0.686 1.00 0.00 ATOM 172 N LYS+ 134 10.867-1.243-0.487 1.00 0.00 ATOM 173 H LYS+ 134 10.511-2.041-0.037 1.00 0.00 ATOM 174 CA LYS+ 134 10.089-0.620-1.545 1.00 0.00 ATOM 175 HA LYS+ 134 10.708 0.134-2.008 1.00 0.00 ATOM 176 CB LYS+ 134 9.708-1.664-2.598 1.00 0.00 ATOM 177 1HB LYS+ 134 8.765-2.110-2.316 1.00 0.00 ATOM 178 2HB LYS+ 134 10.467-2.432-2.616 1.00 0.00 ATOM 179 QB LYS+ 134 9.616-2.271-2.466 1.00 0.00 ATOM 180 CG LYS+ 134 9.567-1.101-4.003 1.00 0.00 ATOM 181 1HG LYS+ 134 10.550-0.991-4.436 1.00 0.00 ATOM 182 2HG LYS+ 134 9.083-0.137-3.946 1.00 0.00 ATOM 183 QG LYS+ 134 9.816-0.564-4.191 1.00 0.00 ATOM 184 CD LYS+ 134 8.734-2.021-4.884 1.00 0.00 ATOM 185 1HD LYS+ 134 7.788-2.211-4.394 1.00 0.00 ATOM 186 2HD LYS+ 134 9.263-2.953-5.018 1.00 0.00 ATOM 187 QD LYS+ 134 8.525-2.582-4.706 1.00 0.00 ATOM 188 CE LYS+ 134 8.467-1.403-6.249 1.00 0.00 ATOM 189 1HE LYS+ 134 7.607-0.751-6.171 1.00 0.00 ATOM 190 2HE LYS+ 134 8.252-2.196-6.951 1.00 0.00 ATOM 191 QE LYS+ 134 7.929-1.474-6.561 1.00 0.00 ATOM 192 NZ LYS+ 134 9.633-0.616-6.745 1.00 0.00 ATOM 193 lHZ LYS+ 134 10.491-1.206-6.739 1.00 0.00 ATOM 194 2HZ LYS+ 134 9.792 0.211-6.136 1.00 0.00 ATOM 195 3HZ LYS+ 134 9.457-0.288-7.716 1.00 0.00 ATOM 196 QZ LYS+ 134 9.913-0.428-6.863 1.00 0.00 ATOM 197 C LYS+ 134 8.834 0.041-1.000 1.00 0.00 ATOM 198 O LYS+ 134 7.876-0.637-0.647 1.00 0.00 ATOM 199 N PHE 135 8.838 1.363-0.955 1.00 0.00 ATOM 200 H PHE 135 9.626 1.852-1.269 1.00 0.00 ATOM 201 CA PHE 135 7.683 2.110-0.477 1.00 0.00 ATOM 202 HA PHE 135 7.106 1.458 0.165 1.00 0.00 ATOM 203 CB PHE 135 8.126 3.341 0.318 1.00 0.00 ATOM 204 1HB PHE 135 8.654 4.014-0.345 1.00 0.00 ATOM 205 2HB PHE 135 8.794 3.029 1.105 1.00 0.00 ATOM 206 QB PHE 135 8.724 3.521 0.380 1.00 0.00 ATOM 207 QD PHE 135 6.877 4.201 1.028 1.00 0.00 ATOM 208 QE PHE 135 5.057 5.472 2.086 1.00 0.00 ATOM 209 QR PHE 135 5.602 5.091 1.769 1.00 0.00 ATOM 210 CG PHE 135 7.002 4.114 0.955 1.00 0.00 ATOM 211 CD1 PHE 135 5.875 3.468 1.437 1.00 0.00 ATOM 212 1HD PHE 135 5.799 2.395 1.346 1.00 0.00 ATOM 213 CE1 PHE 135 4.853 4.180 2.032 1.00 0.00 ATOM 214 1HE PHE 135 3.979 3.663 2.405 1.00 0.00 ATOM 215 CZ PHE 135 4.945 5.551 2.151 1.00 0.00 ATOM 216 HZ PHE 135 4.143 6.109 2.619 1.00 0.00 ATOM 217 CE2 PHE 135 6.061 6.208 1.675 1.00 0.00 ATOM 218 2HE PHE 135 6.136 7.282 1.767 1.00 0.00 ATOM 219 CD2 PHE 135 7.082 5.491 1.082 1.00 0.00 ATOM 220 2HD PHE 135 7.956 6.007 0.709 1.00 0.00 ATOM 221 C PHE 135 6.825 2.522-1.661 1.00 0.00 ATOM 222 O PHE 135 7.279 3.253-2.540 1.00 0.00 ATOM 223 N LEU 136 5.599 2.029-1.694 1.00 0.00 ATOM 224 H LEU 136 5.302 1.432-0.972 1.00 0.00 ATOM 225 CA LEU 136 4.689 2.328-2.783 1.00 0.00 ATOM 226 HA LEU 136 5.236 2.896-3.520 1.00 0.00 ATOM 227 CB LEU 136 4.182 1.036-3.431 1.00 0.00 ATOM 228 1HB LEU 136 3.465 1.301-4.194 1.00 0.00 ATOM 229 2HB LEU 136 3.675 0.455-2.673 1.00 0.00 ATOM 230 QB LEU 136 3.570 0.878-3.433 1.00 0.00 ATOM 231 CG LEU 136 5.261 0.158-4.071 1.00 0.00 ATOM 232 HG LEU 136 6.120 0.. 767-4.306 1.00 0.00 ATOM 233 QD1 LEU 136 5.806-1. 188-2.878 1.00 0.00 ATOM 234 QD2 LEU 136 4.625-0.606-5.665 1.00 0.00 ATOM 235 CD1 LEU 136 5.702-0.929-3.107 1.00 0.00 ATOM 236 1HD1 LEU 136 6.491-0.552-2.473 1.00 0.00 ATOM 237 2HD1 LEU 136 6.065-1.780-3.665 1.00 0.00 ATOM 238 3HD1 LEU 136 4.864-1.231-2.497 1.00 0.00 ATOM 239 CD2 LEU 136 4.748-0.459-5.361 1.00 0.00 ATOM 240 1HD2 LEU 136 3.680-0.309-5.431 1.00 0.00 ATOM 241 2HD2 LEU 136 4.962-1.518-5.362 1.00 0.00 ATOM 242 3HD2 LEU 136 5.233 0.009-6.203 1.00 0.00

ATOM 243 QQD LEU 136 5.216-0.897-4.272 1.00 0.00 ATOM 244 C LEU 136 3.511 3.159-2.302 1.00 0.00 ATOM 245 O LEU 136 2.431 2.630-2.039 1.00 0.00 ATOM 246 N HIS+ 137 3.712 4.465-2.212 1.00 0.00 ATOM 247 H HIS+ 137 4.587 4.835-2.452 1.00 0.00 ATOM 248 CA HIS+ 137 2.649 5.364-1.795 1.00 0.00 ATOM 249 HA HIS+ 137 1.940 4.793-1.208 1.00 0.00 ATOM 250 CB HIS+ 137 3.203 6.526-0.947 1.00 0.00 ATOM 251 1HB HIS+ 137 3.958 7.047-1.519 1.00 0.00 ATOM 252 2HB HIS+ 137 3.654 6.124-0.053 1.00 0.00 ATOM 253 QB HIS+ 137 3.806 6.585-0.786 1.00 0.00 ATOM 254 CG HIS+ 137 2.166 7.537-0.523 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.896 7.836 0.794 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.334 8.322-1.255 1.00 0.00 ATOM 257 1HD HIS+ 137 2.314 7.414 1.586 1.00 0.00 ATOM 258 CE1 HIS+ 137 0. 948 8.755 0.850 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.584 9.068-0.381 1.00 0.00 ATOM 260 2HD HIS+ 137 1.274 8.353-2.335 1.00 0.00 ATOM 261 1HE HIS+ 137 0.534 9.175 1.754 1.00 0.00 ATOM 262 2HE HIS+ 137-0.284 9.491-0.610 1.00 0.00 ATOM 263 C HIS+ 137 1. 957 5.905-3.036 1.00 0.00 ATOM 264 O HIS+ 137 2.507 6.751-3.744 1.00 0.00 ATOM 265 N GLN 138 0.758 5.420-3.305 1.00 0.00 ATOM 266 H GLN 138 0.364 4.744-2.705 1.00 0.00 ATOM 267 CA GLN 138 0.008 5.869-4.466 1.00 0.00 ATOM 268 HA GLN 138 0.348 6.865-4.710 1.00 0.00 ATOM 269 CB GLN 138 0. 258 4.951-5.666 1.00 0.00 ATOM 270 1HB GLN 138-0.568 5.045-6.354 1.00 0.00 ATOM 271 2HB GLN 138 0.312 3.932-5.317 1.00 0.00 ATOM 272 QB GLN 138-0. 128 4.488-5.835 1.00 0.00 ATOM 273 CG GLN 138 1.542 5.263-6.420 1.00 0.00 ATOM 274 1HG GLN 138 1. 921 6.216-6.081 1.00 0.00 ATOM 275 2HG GLN 138 1.322 5.319-7.476 1.00 0.00 ATOM 276 QG GLN 138 1.621 5.767-6.778 1.00 0.00 ATOM 277 CD GLN 138 2.611 4.211-6.206 1.00 0.00 ATOM 278 OE1 GLN 138 2. 372 3.021-6.401 1.00 0.00 ATOM 279 NE2 GLN 138 3.794 4.645-5.794 1.00 0.00 ATOM 280 1HE2 GLN 138 3.910 5.608-5.651 1.00 0.00 ATOM 281 2HE2 GLN 138 4.504 3.986-5.649 1.00 0.00 ATOM 282 QE2 GLN 138 4.207 4.797-5.650 1.00 0.00 ATOM 283 C GLN 138-1.475 5.922-4.155 1.00 0.00 ATOM 284 O GLN 138-2.028 4.999-3.553 1.00 0.00 ATOM 285 N GLU 139-2.113 6.996-4.580 1.00 0.00 ATOM 286 H GLU 139-1.618 7.685-5.062 1.00 0.00 ATOM 287 CA GLU 139-3.532 7.178-4.355 1.00 0.00 ATOM 288 HA GLU 139-3.804 6.613-3.475 1.00 0.00 ATOM 289 CB GLU 139-3. 845 8.657-4.116 1.00 0. 00 ATOM 290 1HB GLU 139-4.761 8.731-3.546 1.00 0.00 ATOM 291 2HB GLU 139-3.984 9.144-5.069 1.00 0.00 ATOM 292 QB GLU 139-4. 373 8.937-4.307 1.00 0.00 ATOM 293 CG GLU 139-2.752 9.395-3.355 1.00 0.00 ATOM 294 1HG GLU 139-2.865 10.455-3.525 1.00 0. 00 ATOM 295 2HG GLU 139-1.792 9.073-3.726 1.00 0.00 ATOM 296 QG GLU 139-2.329 9.764-3.625 1.00 0.00 ATOM 297 CD GLU 139-2.802 9.136-1.864 1.00 0.00 ATOM 298 OE1 GLU 139-1.940 9.677-1.142 1.00 0.00 ATOM 299 OE2 GLU 139-3.701 8.392-1.419 1.00 0.00 ATOM 300 C GLU 139-4.322 6.654-5.542 1.00 0.00 ATOM 301 O GLU 139-3.972 6.898-6.697 1.00 0.00 ATOM 302 N ARG+ 140-5.371 5.916-5.245 1.00 0.00 ATOM 303 H ARG+ 140-5.581 5.751-4.301 1.00 0.00 ATOM 304 CA ARG+ 140-6.223 5.330-6.265 1.00 0.00 ATOM 305 HA ARG+ 140-5.858 5.631-7.235 1.00 0.00 ATOM 306 CB ARG+ 140-6.198 3.802-6.152 1.00 0.00 ATOM 307 1HB ARG+ 140-7.006 3.494-5.504 1.00 0.00 ATOM 308 2HB ARG+ 140-5.262 3.501-5.710 1.00 0.00 ATOM 309 QB ARG+ 140-6.134 3. 497-5.607 1.00 0.00 ATOM 310 CG ARG+ 140-6.352 3. 077-7. 478 1.00 0. 00 ATOM 311 1HG ARG+ 140-6.717 3.776-8. 221 1.00 0.00 ATOM 312 2HG ARG+ 140-7.065 2.274-7.358 1.00 0.00 ATOM 313 QG ARG+ 140-6.891 3. 025-7. 789 1.00 0.00 ATOM 314 CD ARG+ 140-5.025 2.496-7.953 1.00 0. 00

ATOM 315 1HD ARG+ 140-4.457 3.279-8.433 1.00 0.00 ATOM 316 2HD ARG+ 140-5.230 1.714-8.671 1.00 0.00 ATOM 317 QD ARG+ 140-4.844 2.496-8.552 1.00 0.00 ATOM 318 NE ARG+ 140-4.235 1.934-6.850 1.00 0.00 ATOM 319 HE ARG+ 140-4.472 1.030-6.543 1.00 0.00 ATOM 320 CZ ARG+ 140-3.226 2.575-6.253 1.00 0.00 ATOM 321 NH1 ARG+ 140-2.908 3.808-6.632 1.00 0.00 ATOM 322 1HH1 ARG+ 140-3.426 4.257-7.364 1.00 0.00 ATOM 323 2HH1 ARG+ 140-2. 160 4.296-6.183 1.00 0.00 ATOM 324 QH1 ARG+ 140-2.793 4.276-6.773 1.00 0.00 ATOM 325 NH2 ARG+ 140-2.551 1.991-5.268 1.00 0.00 ATOM 326 1HH2 ARG+ 140-2.794 1.066-4.971 1.00 0.00 ATOM 327 2HH2 ARG+ 140-1.799 2.475-4.815 1.00 0.00 ATOM 328 QH2 ARG+ 140-2.297 1.770-4.893 1.00 0.00 ATOM 329 C ARG+ 140-7.646 5.835-6.078 1.00 0.00 ATOM 330 O ARG+ 140-8.464 5.168-5.449 1.00 0.00 ATOM 331 N MET 141-7.934 7.018-6.614 1.00 0.00 ATOM 332 H MET 141-7.234 7.501-7.099 1.00 0.00 ATOM 333 CA MET 141-9.264 7.624-6.495 1.00 0.00 ATOM 334 HA MET 141-9.575 7.535-5.466 1.00 0.00 ATOM 335 CB MET 141-9. 193 9.112-6. 869 1.00 0.00 ATOM 336 1HB MET 141-9.151 9.194-7.946 1.00 0.00 ATOM 337 2HB MET 141-8.293 9.534-6.450 1.00 0.00 ATOM 338 QB MET 141-8. 722 9.364-7.198 1.00 0.00 ATOM 339 CG MET 141-10.377 9.933-6.378 1.00 0.00 ATOM 340 1HG MET 141-11.237 9.283-6.297 1.00 0.00 ATOM 341 2HG MET 141-10.583 10.708-7.101 1.00 0.00 ATOM 342 QG MET 141-10.910 9.995-6.699 1.00 0.00 ATOM 343 SD MET 141-10.079 10.703-4.777 1.00 0.00 ATOM 344 QE MET 141-9.413 12.657-5.383 1.00 0.00 ATOM 345 CE MET 141-9.524 12.330-5.282 1.00 0.00 ATOM 346 1HE MET 141-9.174 12.876-4.418 1.00 0.00 ATOM 347 2HE MET 141-10.344 12.865-5.738 1.00 0.00 ATOM 348 3HE MET 141-8.719 12.230-5.995 1.00 0.00 ATOM 349 C MET 141-10.288 6.907-7.383 1.00 0.00 ATOM 350 O MET 141-11.217 7.524-7.909 1.00 0.00 ATOM 351 N ASP 142-10.107 5.607-7.543 1.00 0.00 ATOM 352 H ASP 142-9.351 5.178-7.098 1.00 0.00 ATOM 353 CA ASP 142-10.982 4.796-8.359 1.00 0.00 ATOM 354 HA ASP 142-11.730 5.440-8.794 1.00 0.00 ATOM 355 CB ASP 142-10.177 4.132-9.478 1.00 0.00 ATOM 356 1HB ASP 142-10.826 3.965-10.314 1.00 0.00 ATOM 357 2HB ASP 142-9.798 3.185-9.129 1.00 0.00 ATOM 358 QB ASP 142-10.312 3.575-9.721 1.00 0.00 ATOM 359 CG ASP 142-9.004 4.972-9.946 1.00 0.00 ATOM 360 OD1 ASP 142-9.171 5.736-10.916 1.00 0.00 ATOM 361 OD2 ASP 142-7.916 4.864-9.339 1.00 0.00 ATOM 362 C ASP 142-11.664 3.725-7.522 1.00 0.00 ATOM 363 O ASP 142-12.890 3.606-7.517 1.00 0.00 ATOM 364 N VAL 143-10.861 2.935-6.822 1.00 0.00 ATOM 365 H VAL 143-9.893 3.074-6.871 1.00 0.00 ATOM 366 CA VAL 143-11.388 1.861-5.992 1.00 0.00 ATOM 367 HA VAL 143-12.361 1.598-6.382 1.00 0.00 ATOM 368 CB VAL 143-10.487 0.609-6.054 1.00 0.00 ATOM 369 HB VAL 143-9.790 0.651-5.228 1.00 0.00 ATOM 370 QG1 VAL 143-11.513-0.959-5.874 1.00 0.00 ATOM 371 QG2 VAL 143-9.499 0.566-7.656 1.00 0.00 ATOM 372 CG1 VAL 143-11.317-0.658-5.909 1.00 0.00 ATOM 373 1HG1 VAL. 143-11. 022-1.368-6.667 1.00 0.00 ATOM 374 2HG1 VAL 143-12.363-0.420-6.026 1.00 0.00 ATOM 375 3HG1 VAL 143-11.152-1.088-4.931 1.00 0.00 ATOM 376 CG2 VAL 143-9.687 0. 574-7. 350 1.00 0.00 ATOM 377 1HG2 VAL 143-9.785-0.400-7.806 1.00 0.00 ATOM 378 2HG2 VAL 143-8.647 0.770-7.136 1.00 0.00 ATOM 379 3HG2 VAL 143-10.064 1.328-8.026 1.00 0.00 ATOM 380 QQG VAL 143-10.506-0.197-6.765 1.00 0.00 ATOM 381 C VAL 143-11.551 2.327-4.543 1.00 0.00 ATOM 382 O VAL 143-10.820 3.199-4.075 1.00 0.00 ATOM 383 N CYS 144-12.525 1.755-3.840 1.00 0.00 ATOM 384 H CYS 144-13.081 1.073-4.266 1.00 0.00 ATOM 385 CA CYS 144-12.797 2.128-2.453 1.00 0.00 ATOM 386 HA CYS 144-11.934 2.657-2.068 1.00 0.00

ATOM 387 CB CYS 144-14. 016 3.051-2.390 1.00 0.00 ATOM 388 1HB CYS 144-14.174 3.353-1.366 1.00 0.00 ATOM 389 2HB CYS 144-14. 883 2.508-2.735 1.00 0.00 ATOM 390 QB CYS 144-14. 529 2.930-2.050 1.00 0.00 ATOM 391 SG CYS 144-13.873 4.562-3.401 1.00 0.00 ATOM 392 C CYS 144-13.048 0.903-1.585 1.00 0.00 ATOM 393 0CYS 144-14. 186 0.449-1.453 1.00 0.00 ATOM 394 N GLU 145-11.988 0.376-0.992 1.00 0.00 ATOM 395 H GLU 145-11.107 0.784-1.132 1.00 0.00 ATOM 396 CA GLU 145-12.095-0.795-0.138 1.00 0.00 ATOM 397 HA GLU 145-13. 136-1. 078-0.100 1.00 0.00 ATOM 398 CB GLU 145-11. 295-1.940-0.748 1.00 0.00 ATOM 399 1HB GLU 145-10. 993-2.617 0.034 1.00 0.00 ATOM 400 2HB GLU 145-10.411-1.535-1.221 1.00 0.00 ATOM 401 QB GLU 145-10.702-2.076-0.593 1.00 0.00 ATOM 402 CG GLU 145-12.080-2.730-1.787 1.00 0.00 ATOM 403 1HG GLU 145-12.699-2.045-2.348 1.00 0.00 ATOM 404 2HG GLU 145-12.707-3.445-1.279 1.00 0.00 ATOM 405 QG GLU 145-12.703-2.745-1.813 1.00 0.00 ATOM 406 CD GLU 145-11.190-3.477-2.756 1.00 0.00 ATOM 407 OE1 GLU 145-11.433-3.381-3.975 1.00 0.00 ATOM 408 OE2 GLU 145-10.253-4.160-2.295 1.00 0.00 ATOM 409 C GLU 145-11.619-0.485 1.281 1.00 0.00 ATOM 410 O GLU 145-11.255 0.649 1.585 1.00 0.00 ATOM 411 N THR 146-11.651-1.488 2.151 1. 00 0.00 ATOM 412 H THR 146-11. 969-2.364 1.856 1.00 0.00 ATOM 413 CA THR 146-11.254-1.311 3.546 1.00 0.00 ATOM 414 HA THR 146-11.561-0.321 3.852 1.00 0.00 ATOM 415 CB THR 146-11.975-2.345 4.416 1.00 0.00 ATOM 416 HB THR 146-11.358-3.230 4.488 1.00 0.00 ATOM 417 QG2 THR 146-12. 329-1.750 6.160 1.00 0.00 ATOM 418 OG1 THR 146-13.213-2.714 3.831 1.00 0.00 ATOM 419 1HG THR 146-13.933-2.267 4.300 1.00 0.00 ATOM 420 CG2 THR 146-12.260-1.865 5.824 1.00 0.00 ATOM 421 1HG2 THR 146-13. 089-2.422 6.236 1.00 0.00 ATOM 422 2HG2 THR 146-12.510-0.812 5.803 1.00 0.00 ATOM 423 3HG2 THR 146-11.386-2.014 6.441 1.00 0.00 ATOM 424 C THR 146-9.739-1.433 3.726 1.00 0.00 ATOM 425 O THR 146-9.014-1.782 2.793 1.00 0.00 ATOM 426 N HIS+ 147-9.279-1.148 4.945 1.00 0.00 ATOM 427 H HIS+ 147-9.922-0.881 5.636 1.00 0.00 ATOM 428 CA HIS+ 147-7. 859-1. 218 5.297 1.00 0.00 ATOM 429 HA HIS+ 147-7.329-0.492 4.700 1.00 0.00 ATOM 430 CB HIS+ 147-7.679-0.873 6.780 1.00 0.00 ATOM 431 1HB HIS+ 147-7.703-1.787 7.357 1.00 0.00 ATOM 432 2HB HIS+ 147-8.492-0.236 7.095 1.00 0.00 ATOM 433 QB HIS+ 147-8.098-1.012 7.226 1. 00 0.00 ATOM 434 CG HIS+ 147-6.397-0.165 7.094 1.00 0.00 ATOM 435 ND1 HIS+ 147-6. 313 1.202 7.260 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.142-0.644 7.289 1.00 0.00 ATOM 437 1HD HIS+ 147-7. 058 1.839 7.171 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.066 1.534 7.546 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.335 0.433 7.570 1.00 0.00 ATOM 440 2HD HIS+ 147-4.829-1.678 7.209 1.00 0.00 ATOM 441 1HE HIS+ 147-4.705 2.536 7.729 1.00 0.00 ATOM 442 2HE HIS+ 147-3.355 0.408 7.633 1.00 0.00 ATOM 443 C HIS+ 147-7.281-2.605 5.025 1.00 0.00 ATOM 444 O HIS+ 147-6.139-2.734 4.593 1.00 0.00 ATOM 445 N LEU 148-8.076-3.638 5.284 1.00 0.00 ATOM 446 H LEU 148-8.978-3.473 5.626 1.00 0.00 ATOM 447 CA LEU 148-7. 637-5.012 5.069 1.00 0.00 ATOM 448 HA LEU 148-6.648-5.113 5.491 1.00 0.00 ATOM 449 CB LEU 148-8.584-5.986 5. 779 1.00 0. 00 ATOM 450 1HB LEU 148-9. 599-5.716 5. 530 1.00 0.00 ATOM 451 2HB LEU 148-8.450-5.872 6.845 1.00 0.00 ATOM 452 QB LEU 148-9.025-5.794 6.188 1.00 0.00 ATOM 453 CG LEU 148-8.383-7.460 5.425 1.00 0.00 ATOM 454 HG LEU 148-8.096-7.536 4.386 1.00 0.00 ATOM 455 QD1 LEU 148-7.008-8.213 6.462 1. 00 0.00 ATOM 456 QD2 LEU 148-9. 981-8. 421 5.661 1. 00 0. 00 ATOM 457 CD1 LEU 148-7.271-8.068 6.263 1.00 0.00 ATOM 458 1HD1 LEU 148-6.331-7.971 5.739 1.00 0.00

ATOM 459 2HD1 LEU 148-7.481-9.113 6.435 1.00 0. 00 ATOM 460 3HD1 LEU 148-7.210-7.553 7.210 1.00 0.00 ATOM 461 CD2 LEU 148-9.675-8.236 5.615 1.00 0.00 ATOM 462 1HD2 LEU 148-10.336-8.045 4.783 1.00 0.00 ATOM 463 2HD2 LEU 148-10.152-7.925 6.533 1.00 0.00 ATOM 464 3HD2 LEU 148-9. 455-9.293 5.665 1.00 0.00 ATOM 465 QQD LEU 148-8.494-8.317 6.061 1.00 0.00 ATOM 466 C LEU 148-7.572-5.330 3.582 1.00 0.00 ATOM 467 O LEU 148-6.690-6.059 3.133 1.00 0.00 ATOM 468 N HIS+ 149-8. 505-4. 772 2.825 1.00 0.00 ATOM 469 H HIS+ 149-9.174-4.195 3.243 1.00 0.00 ATOM 470 CA HIS+ 149-8.555-4.987 1.386 1.00 0.00 ATOM 471 HA HIS+ 149-8.602-6.052 1.212 1.00 0.00 ATOM 472 CB HIS+ 149-9.799-4.334 0.799 1.00 0.00 ATOM 473 1HB HIS+ 149-9.601-4.067-0.232 1.00 0.00 ATOM 474 2HB HIS+ 149-10. 027-3.439 1.357 1.00 0. 00 ATOM 475 QB HIS+ 149-9.814-3.753 0.563 1.00 0.00 ATOM 476 CG HIS+ 149-11.010-5.214 0.819 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.998-5.131 1.780 1.00 0.00 ATOM 478 CD2 HIS+ 149-11.394-6.196-0.028 1.00 0.00 ATOM 479 1HD HIS+ 149-12.016-4.502 2.534 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.934-6.027 1.522 1.00 0.00 ATOM 481 NE2 HIS+ 149-12.592-6.686 0.427 1.00 0.00 ATOM 482 2HD HIS+ 149-10.860-6.524-0.911 1.00 0.00 ATOM 483 1HE HIS+ 149-13.829-6.192 2.104 1.00 0.00 ATOM 484 2HE HIS+ 149-13.190-7.272-0.085 1.00 0.00 ATOM 485 C HIS+ 149-7.300-4.439 0.720 1.00 0.00 ATOM 486 O HIS+ 149-6.581-5.174 0.047 1.00 0.00 ATOM 487 N TRP 150-7. 027-3.152 0.933 1.00 0.00 ATOM 488 H TRP 150-7.632-2.619 1.493 1.00 0.00 ATOM 489 CA TRP 150-5. 835-2.520 0.365 1.00 0.00 ATOM 490 HA TRP 150-5. 866-2.643-0.708 1.00 0.00 ATOM 491 CB TRP 150-5. 777-1.032 0.716 1.00 0.00 ATOM 492 1HB TRP 150-4.806-0.648 0.433 1.00 0.00 ATOM 493 2HB TRP 150-5.899-0.921 1.782 1.00 0.00 ATOM 494 QB TRP 150-5. 353-0.785 1.108 1.00 0.00 ATOM 495 CG TRP 150-6.818-0.184 0.049 1.00 0.00 ATOM 496 CD1 TRP 150-7.267 1.033 0.475 1.00 0.00 ATOM 497 CD2 TRP 150-7.533-0.472-1.157 1.00 0.00 ATOM 498 CE3 TRP 150-7. 530-1.540-2.057 1.00 0.00 ATOM 499 CE2 TRP 150-8.397 0.612-1.396 1.00 0.00 ATOM 500 NE1 TRP 150-8. 217 1.515-0.387 1.00 0.00 ATOM 501 HD TRP 150-6. 917 1.532 1.367 1.00 0.00 ATOM 502 3HE TRP 150-6. 886-2.392-1.912 1.00 0.00 ATOM 503 CZ3 TRP 150-8.372-1.492-3.144 1.00 0.00 ATOM 504 CZ2 TRP 150-9.242 0.658-2.494 1.00 0.00 ATOM 505 1HE TRP 150-8. 691 2.369-0.296 1.00 0.00 ATOM 506 3HZ TRP 150-8. 390-2.313-3.846 1.00 0. 00 ATOM 507 CH2 TRP 150-9.216-0.401-3.353 1.00 0.00 ATOM 508 2HZ TRP 150-9.904 1.494-2.674 1.00 0.00 ATOM 509 HH TRP 150-9.861-0.411-4.219 1.00 0.00 ATOM 510 C TRP 150-4.587-3.202 0.878 1.00 0.00 ATOM 511 O TRP 150-3. 612-3.324 0.151 1.00 0.00 ATOM 512 N HIS+ 151-4.631-3.665 2.122 1.00 0.00 ATOM 513 H HIS+ 151-5.450-3.550 2.649 1.00 0.00 ATOM 514 CA HIS+ 151-3.499-4.366 2.703 1.00 0.00 ATOM 515 HA HIS+ 151-2.647-3.703 2.687 1.00 0.00 ATOM 516 CB HIS+ 151-3.806-4.780 4.154 1.00 0.00 ATOM 517 1HB HIS+ 151-4. 686-5.409 4.156 1.00 0.00 ATOM 518 2HB HIS+ 151-4. 009-3.893 4.735 1.00 0.00 ATOM 519 QB HIS+ 151-4.348-4.651 4.446 1.00 0.00 ATOM 520 CG HIS+ 151-2.701-5.534 4.845 1.00 0.00 ATOM 521 ND1 HIS+ 151-2. 641-5.699 6.212 1.00 0.00 ATOM 522 CD2 HIS+ 151-1.618-6.178 4.348 1.00 0.00 ATOM 523 1HD HIS+ 151-3.287-5.344 6.863 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.569-6.409 6.522 1.00 0.00 ATOM 525 NE2 HIS+ 151-0.932-6.712 5.409 1.00 0.00 ATOM 526 2HD HIS+ 151-1.357-6.267 3.297 1.00 0.00 ATOM 527 1HE HIS+ 151-1. 264-6.689 7.520 1.00 0.00 ATOM 528 2HE HIS+ 151-0. 044-7.125 5.363 1.00 0.00 ATOM 529 C HIS+ 151-3.202-5.589 1.853 1.00 0.00 ATOM 530 O HIS+ 151-2.061-5.832 1.473 1.00 0.00

ATOM 531 N THR 152-4.247-6.340 1.554 1.00 0.00 ATOM 532 H THR 152-5.131-6.077 1.887 1.00 0.00 ATOM 533 CA THR 152-4.131-7.534 0.742 1.00 0.00 ATOM 534 HA THR 152-3.410-8.188 1.209 1.00 0.00 ATOM 535 CB THR 152-5.489-8.241 0.684 1.00 0.00 ATOM 536 HB THR 152-6.182-7.622 0. 129 1.00 0.00 ATOM 537 QG2 THR 152-5.446-9.927-0.131 1.00 0.00 ATOM 538 OG1 THR 152-6.001-8.422 1.993 1.00 0.00 ATOM 539 1HG THR 152-6.392-7.595 2.304 1.00 0.00 ATOM 540 CG2 THR 152-5.453-9.603 0.027 1.00 0.00 ATOM 541 1HG2 THR 152-4.832-9.561-0.859 1.00 0.00 ATOM 542 2HG2 THR 152-6.455-9.892-0.253 1.00 0.00 ATOM 543 3HG2 THR 152-5.050-10.327 0.717 1.00 0.00 ATOM 544 C THR 152-3. 622-7. 199-0.649 1.00 0.00 ATOM 545 O THR 152-2.626-7.775-1.069 1.00 0.00 ATOM 546 N VAL 153-4.280-6.264-1.339 1.00 0.00 ATOM 547 H VAL 153-5.057-5.822-0.927 1.00 0.00 ATOM 548 CA VAL 153-3.859-5.867-2.687 1.00 0.00 ATOM 549 HA VAL 153-3. 935-6.733-3.325 1.00 0.00 ATOM 550 CB VAL 153-4.757-4.749-3.262 1.00 0.00 ATOM 551 HB VAL 153-4.569-3.842-2.709 1.00 0.00 ATOM 552 QG1 VAL 153-4.354-4.432-5.071 1.00 0.00 ATOM 553 QG2 VAL 153-6.576-5.196-3.068 1.00 0.00 ATOM 554 CG1 VAL 153-4.430-4.492-4.725 1.00 0.00 ATOM 555 1HG1 VAL 153-3.378-4.665-4.896 1.00 0.00 ATOM 556 2HG1 VAL 153-4.674-3.470-4.974 1.00 0.00 ATOM 557 3HG1 VAL 153-5.010-5.161-5.345 1.00 0.00 ATOM 558 CG2 VAL 153-6.227-5.110-3.105 1.00 0.00 ATOM 559 1HG2 VAL 153-6.509-5.033-2.065 1.00 0.00 ATOM 560 2HG2 VAL 153-6.388-6.122-3.447 1.00 0.00 ATOM 561 3HG2 VAL 153-6.830-4.433-3.692 1.00 0.00 ATOM 562 QQG VAL 153-5.465-4.814-4.070 1.00 0.00 ATOM 563 C VAL 153-2.412-5.413-2.679 1.00 0.00 ATOM 564 O VAL 153-1.602-5.856-3.494 1.00 0.00 ATOM 565 N ALA 154-2.091-4.552-1.734 1.00 0.00 ATOM 566 H ALA 154-2.790-4.254-1.103 1.00 0.00 ATOM 567 CA ALA 154-0.737-4.055-1.579 1.00 0.00 ATOM 568 HA ALA 154-0.452-3.531-2.479 1.00 0.00 ATOM 569 QB ALA 154-0.672-2.861-0.135 1.00 0.00 ATOM 570 CB ALA 154-0.684-3.090-0.412 1.00 0.00 ATOM 571 1HB ALA 154-0.087-2.231-0.682 1.00 0.00 ATOM 572 2HB ALA 154-0.243-3.582 0.441 1.00 0.00 ATOM 573 3HB ALA 154-1.686-2.769-0.164 1.00 0.00 ATOM 574 C ALA 154 0.225-5.208-1.342 1.00 0.00 ATOM 575 O ALA 154 1.284-5.297-1.966 1.00 0.00 ATOM 576 N LYS+ 155-0. 160-6.089-0.427 1.00 0.00 ATOM 577 H LYS+ 155-1. 018-5. 950 0.031 1.00 0.00 ATOM 578 CA LYS+ 155 0.645-7.245-0.079 1.00 0.00 ATOM 579 HA LYS+ 155 1.608-6.884 0.274 1.00 0.00 ATOM 580 CB LYS+ 155-0.025-8.053 1.041 1.00 0.00 ATOM 581 1HB LYS+ 155-1.080-8.130 0.825 1.00 0.00 ATOM 582 2HB LYS+ 155 0.101-7.524 1.974 1.00 0.00 ATOM 583 QB LYS+ 155-0.490-7.827 1.400 1.00 0.00 ATOM 584 CG LYS+ 155 0.531-9.463 1.211 1.00 0.00 ATOM 585 1HG LYS+ 155 1.193-9.476 2.066 1.00 0.00 ATOM 586 2HG LYS+ 155 1.084-9.732 0.323 1.00 0.00 ATOM 587 QG LYS+ 155 1.138-9.604 1.195 1.00 0.00 ATOM 588 CD LYS+ 155-0.577-10.488 1.429 1.00 0.00 ATOM 589 1HD LYS+ 155-1.405-10.008 1.931 1.00 0.00 ATOM 590 2HD LYS+ 155-0. 194-11. 286 2.049 1.00 0.00 ATOM 591 QD LYS+ 155-0. 800-10.647 1.990 1.00 0.00 ATOM 592 CE LYS+ 155-1.067-11.083 0.111 1.00 0.00 ATOM 593 1HE LYS+ 155-1.237-12.142 0.250 1.00 0.00 ATOM 594 2HE LYS+ 155-0.304-10.939-0.641 1.00 0.00 ATOM 595 QE LYS+ 155-0.771-11.541-0.195 1.00 0.00 ATOM 596 NZ LYS+ 155-2.331-10.447-0.356 1.00 0. 00 ATOM 597 1HZ LYS+ 155-2.615-10.836-1.294 1.00 0.00 ATOM 598 2HZ LYS+ 155-2.207-9.418-0.460 1.00 0.00 ATOM 599 3HZ LYS+ 155-3.099-10.624 0.317 1.00 0.00 ATOM 600 QZ LYS+ 155-2.641-10.293-0.479 1.00 0.00 ATOM 601 C LYS+ 155 0.884-8.133-1.286 1.00 0.00 ATOM 602 O LYS+ 155 2.033-8.417-1.590 1.00 0.00

ATOM 603 N GLU 156-0.185-8.588-1.965 1.00 0.00 ATOM 604 H GLU 156-1.098-8.340-1.671 1.00 0.00 ATOM 605 CA GLU 156 0.003-9.467-3.125 1.00 0.00 ATOM 606 HA GLU 156 0.524-10.342-2.760 1.00 0.00 ATOM 607 CB GLU 156-1.304-9.936-3.784 1.00 0.00 ATOM 608 1HB GLU 156-1.587-10.885-3.350 1.00 0.00 ATOM 609 2HB GLU 156-1.120-10.085-4.837 1.00 0.00 ATOM 610 QB GLU 156-1.354-10.485-4.093 1.00 0.00 ATOM 611 CG GLU 156-2.481-8.996-3.653 1.00 0.00 ATOM 612 1HG GLU 156-2.705-8.578-4.624 1.00 0.00 ATOM 613 2HG GLU 156-2. 225-8.202-2.967 1.00 0.00 ATOM 614 QG GLU 156-2.465-8.390-3.795 1.00 0.00 ATOM 615 CD GLU 156-3.710-9.710-3.137 1.00 0.00 ATOM 616 OE1 GLU 156-3. 561-10.843-2.628 1.00 0.00 ATOM 617 OE2 GLU 156-4.809-9.135-3.216 1.00 0.00 ATOM 618 C GLU 156 0.896-8.818-4.164 1.00 0.00 ATOM 619 O GLU 156 1.771-9.476-4.698 1.00 0.00 ATOM 620 N THR 157 0.694-7.532-4.432 1.00 0.00 ATOM 621 H THR 157-0.022-7.045-3.961 1.00 0.00 ATOM 622 CA THR 157 1.529-6.826-5.404 1.00 0.00 ATOM 623 HA THR 157 1.360-7.278-6.371 1.00 0.00 ATOM 624 CB THR 157 1.138-5.344-5.466 1.00 0.00 ATOM 625 HB THR 157 1.374-4.881-4.518 1.00 0.00 ATOM 626 QG2 THR 157 2.029-4.390-6.809 1.00 0.00 ATOM 627 OG1 THR 157-0.253-5.198-5.699 1.00 0.00 ATOM 628 1HG THR 157-0.747-5.548-4.945 1.00 0.00 ATOM 629 CG2 THR 157 1.858-4.573-6.551 1.00 0.00 ATOM 630 1HG2 THR 157 2.641-5.188-6.972 1.00 0.00 ATOM 631 2HG2 THR 157 2.290-3.678-6.130 1.00 0.00 ATOM 632 3HG2 THR 157 1.156-4.304-7.327 1.00 0.00 ATOM 633 C THR 157 3.018-6.974-5.052 1.00 0.00 ATOM 634 O THR 157 3. 864-7.161-5.927 1.00 0.00 ATOM 635 N CYS 158 3.328-6.895-3.764 1.00 0.00 ATOM 636 H CYS 158 2.610-6.741-3.107 1.00 0. 00 ATOM 637 CA CYS 158 4.705-7.026-3.295 1.00 0.00 ATOM 638 HA CYS 158 5.349-6.549-4.019 1.00 0.00 ATOM 639 CB CYS 158 4.854-6.299-1.965 1.00 0.00 ATOM 640 1HB CYS 158 5.759-6.614-1.483 1.00 0.00 ATOM 641 2HB CYS 158 4.016-6.550-1.335 1.00 0.00 ATOM 642 QB CYS 158 4.887-6.582-1.409 1.00 0.00 ATOM 643 SG CYS 158 4.902-4.478-2.137 1.00 0.00 ATOM 644 C CYS 158 5.133-8.496-3.175 1.00 0.00 ATOM 645 O CYS 158 6.229-8.856-3.609 1.00 0.00 ATOM 646 N SER 159 4.281-9.340-2.583 1.00 0.00 ATOM 647 H SER 159 3.427-8.998-2.244 1.00 0.00 ATOM 648 CA SER 159 4.593-10.763-2.411 1.00 0.00 ATOM 649 HA SER 159 5.575-10.823-1.965 1.00 0. 00 ATOM 650 CB SER 159 3.588-11.435-1.470 1.00 0. 00 ATOM 651 1HB SER 159 3.747-11.076-0.464 1.00 0. 00 ATOM 652 2HB SER 159 3.740-12.505-1.497 1.00 0.00 ATOM 653 QB SER 159 3.743-11.791-0.980 1.00 0.00 ATOM 654 OG SER 159 2.250-11.156-1.851 1.00 0.00 ATOM 655 HG SER 159 2.195-11.109-2.814 1.00 0.00 ATOM 656 C SER 159 4.632-11.506-3.749 1.00 0.00 ATOM 657 O SER 159 5.245-12.566-3.848 1.00 0.00 ATOM 658 N GLU 160 3.989-10.942-4.775 1.00 0.00 ATOM 659 H GLU 160 3.521-10.088-4.638 1.00 0.00 ATOM 660 CA GLU 160 3.977-11.547-6.107 1.00 0.00 ATOM 661 HA GLU 160 3.651-12.573-6.015 1.00 0.00 ATOM 662 CB GLU 160 3.024-10.780-7.033 1.00 0.00 ATOM 663 1HB GLU 160 3.417-9.785-7.185 1.00 0.00 ATOM 664 2HB GLU 160 2.059-10.704-6.554 1.00 0.00 ATOM 665 QB GLU 160 2.738-10.245-6.869 1.00 0.00 ATOM 666 CG GLU 160 2.827-11.420-8.399 1.00 0.00 ATOM 667 1HG GLU 160 1.768-11.495-8. 600 1.00 0.00 ATOM 668 2HG GLU 160 3. 263-12.408-8. 386 1.00 0. 00 ATOM 669 QG GLU 160 2.515-11.952-8.493 1.00 0.00 ATOM 670 CD GLU 160 3.477-10.619-9. 503 1.00 0.00 ATOM 671 OE1 GLU 160 3.862-9.457-9.249 1.00 0.00 ATOM 672 OE2 GLU 160 3.644-11.155-10. 614 1.00 0.00 ATOM 673 C GLU 160 5.391-11.514-6.671 1. 00 0. 00 ATOM 674 O GLU 160 5.786-12.340-7.497 1.00 0.00

ATOM 675 N LYS+ 161 6.153-10.552-6.185 1.00 0.00 ATOM 676 H LYS+ 161 5.778-9.944-5.516 1.00 0.00 ATOM 677 CA LYS+ 161 7.527-10.386-6.581 1.00 0.00 ATOM 678 HA LYS+ 161 7.687-10.948-7.489 1.00 0.00 ATOM 679 CB LYS+ 161 7.833-8.904-6.828 1.00 0.00 ATOM 680 1HB LYS+ 161 8.189-8.468-5.905 1.00 0.00 ATOM 681 2HB LYS+ 161 6.920-8.407-7.118 1.00 0.00 ATOM 682 QB LYS+ 161 7.554-8.438-6.511 1.00 0.00 ATOM 683 CG LYS+ 161 8.880-8.657-7.909 1.00 0.00 ATOM 684 1HG LYS+ 161 9.846-8.972-7.537 1.00 0.00 ATOM 685 2HG LYS+ 161 8.908-7.602-8.133 1.00 0.00 ATOM 686 QG LYS+ 161 9.377-8.287-7.835 1.00 0.00 ATOM 687 CD LYS+ 161 8.569-9.425-9.189 1.00 0.00 ATOM 688 1HD LYS+ 161 8.518-10.480-8.960 1.00 0.00 ATOM 689 2HD LYS+ 161 9.362-9.248-9.903 1.00 0.00 ATOM 690 QD LYS+ 161 8.940-9.864-9.431 1.00 0.00 ATOM 691 CE LYS+ 161 7.246-8.984-9.803 1.00 0.00 ATOM 692 1HE LYS+ 161 7.445-8.500-10.749 1.00 0.00 ATOM 693 2HE LYS+ 161 6.772-8.280-9.134 1.00 0.00 ATOM 694 QE LYS+ 161 7.108-8.390-9.941 1.00 0.00 ATOM 695 NZ LYS+ 161 6.322-10.129-10.028 1.00 0.00 ATOM 696 1HZ LYS+ 161 6.351-10.436-11.018 1.00 0.00 ATOM 697 2HZ LYS+ 161 5.333-9.845-9.801 1. 00 0.00 ATOM 698 3HZ LYS+ 161 6.575-10.932-9.417 1.00 0.00 ATOM 699 QZ LYS+ 161 6.086-10.405-10.078 1.00 0.00 ATOM 700 C LYS+ 161 8.412-10.952-5.481 1.00 0.00 ATOM 701 O LYS+ 161 8.120-12.006-4.924 1.00 0.00 ATOM 702 N SER 162 9.484-10.260-5.162 1.00 0.00 ATOM 703 H SER 162 9.676-9.426-5.629 1.00 0. 00 ATOM 704 CA SER 162 10.381-10.718-4.125 1.00 0.00 ATOM 705 HA SER 162 10.037-11.684-3.794 1.00 0.00 ATOM 706 CB SER 162 11.796-10.860-4.686 1.00 0.00 ATOM 707 1HB SER 162 12.124-11.884-4.572 1.00 0. 00 ATOM 708 2HB SER 162 12.463-10.208-4.138 1.00 0.00 ATOM 709 QB SER 162 12.293-11.046-4.355 1.00 0.00 ATOM 710 OG SER 162 11.835-10.511-6.066 1.00 0.00 ATOM 711 HG SER 162 12.645-10.850-6.455 1.00 0.00 ATOM 712 C SER 162 10.385-9.761-2.937 1.00 0.00 ATOM 713 O SER 162 11.445-9.377-2.458 1.00 0.00 ATOM 714 N THR 163 9.207-9.361-2.457 1.00 0.00 ATOM 715 H THR 163 8.372-9.680-2.870 1.00 0.00 ATOM 716 CA THR 163 9.145-8.451-1.317 1.00 0.00 ATOM 717 HA THR 163 10.065-8.561-0.758 1.00 0.00 ATOM 718 CB THR 163 9.019-6.995-1.767 1.00 0.00 ATOM 719 HB THR 163 8.913-6.380-0.879 1.00 0.00 ATOM 720 QG2 THR 163 10.489-6.353-2.735 1.00 0.00 ATOM 721 OG1 THR 163 7.872-6.816-2.575 1.00 0.00 ATOM 722 1HG THR 163 7.665-7.643-3.031 1.00 0.00 ATOM 723 CG2 THR 163 10.206-6.475-2.549 1.00 0.00 ATOM 724 1HG2 THR 163 10.767-5.785-1.937 1.00 0.00 ATOM 725 2HG2 THR 163 9.859-5.969-3.437 1.00 0.00 ATOM 726 3HG2 THR 163 10.841-7.304-2.831 1.00 0.00 ATOM 727 C THR 163 7.978-8.783-0.395 1.00 0.00 ATOM 728 O THR 163 7.013-9.435-0.789 1.00 0.00 ATOM 729 N ASN 164 8.075-8.308 0.836 1.00 0.00 ATOM 730 H ASN 164 8.875-7.789 1.081 1.00 0.00 ATOM 731 CA ASN 164 7.033-8.528 1.840 1.00 0.00 ATOM 732 HA ASN 164 6.192-9.008 1.349 1.00 0.00 ATOM 733 CB ASN 164 7.553-9.430 2.965 1.00 0.00 ATOM 734 1HB ASN 164 7.366-10.459 2.706 1.00 0.00 ATOM 735 2HB ASN 164 7.032-9.193 3.881 1.00 0.00 ATOM 736 QB ASN 164 7.199-9.826 3.294 1.00 0.00 ATOM 737 CG ASN 164 9.042-9.259 3.200 1.00 0.00 ATOM 738 OD1 ASN 164 9.764-10.229 3.385 1.00 0.00 ATOM 739 ND2 ASN 164 9.502-8.015 3.208 1.00 0.00 ATOM 740 1HD2 ASN 164 8.858-7.285 3.083 1.00 0.00 ATOM 741 2HD2 ASN 164 10.464-7.878 3.280 1.00 0.00 ATOM 742 QD2 ASN 164 9.661-7.582 3.182 1.00 0.00 ATOM 743 C ASN 164 6.577-7.198 2.431 1.00 0.00 ATOM 744 O ASN 164 7.404-6.341 2.738 1.00 0.00 ATOM 745 N LEU 165 5.272-7.024 2.591 1.00 0. 00 ATOM 746 H LEU 165 4.658-7.742 2.332 1.00 0.00

ATOM 747 CA LEU 165 4.728-5.784 3.148 1.00 0.00 ATOM 748 HA LEU 165 5.208-4.950 2.655 1.00 0.00 ATOM 749 CB LEU 165 3.219-5.702 2.913 1.00 0.00 ATOM 750 1HB LEU 165 2.730-5.592 3.867 1.00 0.00 ATOM 751 2HB LEU 165 2.891-6.627 2.462 1.00 0.00 ATOM 752 QB LEU 165 2.810-6.110 3.165 1.00 0.00 ATOM 753 CG LEU 165 2.767-4.554 2.031 1.00 0.00 ATOM 754 HG LEU 165 3.302-3.657 2.309 1.00 0.00 ATOM 755 QD1 LEU 165 3.152-4.932 0.241 1.00 0.00 ATOM 756 QD2 LEU 165 0.930-4.238 2.266 1.00 0.00 ATOM 757 CD1 LEU 165 3.079-4.859 0.586 1.00 0.00 ATOM 758 1HD1 LEU 165 3.362-5.896 0.490 1.00 0. 00 ATOM 759 2HD1 LEU 165 3.890-4.230 0.251 1.00 0. 00 ATOM 760 3HD1 LEU 165 2.204-4.668-0.019 1.00 0.00 ATOM 761 CD2 LEU 165 1.283-4.299 2.221 1.00 0.00 ATOM 762 1HD2 LEU 165 1. 016-3. 364 1.750 1.00 0.00 ATOM 763 2HD2 LEU 165 1.057-4.248 3.276 1.00 0.00 ATOM 764 3HD2 LEU 165 0.718-5.102 1.771 1.00 0.00 ATOM 765 QQD LEU 165 2.041-4.585 1.253 1.00 0.00 ATOM 766 C LEU 165 5.005-5.682 4.636 1.00 0.00 ATOM 767 O LEU 165 4.658-6.576 5.405 1.00 0.00 ATOM 768 N HIS+ 166 5.617-4.579 5.030 1.00 0.00 ATOM 769 H HIS+ 166 5.859-3.900 4.364 1.00 0.00 ATOM 770 CA HIS+ 166 5.932-4.337 6.424 1.00 0.00 ATOM 771 HA HIS+ 166 5.629-5.205 6.990 1.00 0.00 ATOM 772 CB HIS+ 166 7.442-4.126 6.594 1.00 0.00 ATOM 773 1HB HIS+ 166 7.743-3.264 6. 013 1.00 0.00 ATOM 774 2HB HIS+ 166 7.965-4.997 6.232 1.00 0.00 ATOM 775 QB HIS+ 166 7.854-4.131 6.123 1.00 0.00 ATOM 776 CG HIS+ 166 7.868-3.892 8.011 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.812-4.859 8.991 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.348-2.781 8.608 1.00 0.00 ATOM 779 1HD HIS+ 166 7.500-5.781 8.871 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.241-4.346 10.133 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.573-3.082 9.925 1.00 0.00 ATOM 782 2HD HIS+ 166 8.508-1.818 8.132 1.00 0.00 ATOM 783 1HE HIS+ 166 8.308-4.870 11.075 1.00 0.00 ATOM 784 2HE HIS+ 166 8.710-2.417 10.632 1.00 0.00 ATOM 785 C HIS+ 166 5.161-3.120 6.931 1.00 0.00 ATOM 786 O HIS+ 166 4.510-3.180 7.975 1.00 0. 00 ATOM 787 N ASP 167 5.236-2.019 6.185 1.00 0. 00 ATOM 788 H ASP 167 5.771-2.034 5.360 1.00 0.00 ATOM 789 CA ASP 167 4.546-0.786 6.577 1.00 0.00 ATOM 790 HA ASP 167 4.050-0.976 7.516 1.00 0.00 ATOM 791 CB ASP 167 5.541 0.368 6.773 1.00 0.00 ATOM 792 1HB ASP 167 5.118 1.079 7.468 1.00 0. 00 ATOM 793 2HB ASP 167 5.700 0.857 5.824 1.00 0.00 ATOM 794 QB ASP 167 5.409 0.968 6.646 1.00 0.00 ATOM 795 CG ASP 167 6.885-0.077 7.307 1.00 0.00 ATOM 796 OD1 ASP 167 7.100 0.025 8.532 1.00 0.00 ATOM 797 OD2 ASP 167 7.728-0.526 6.499 1.00 0.. 00 ATOM 798 C ASP 167 3.501-0.367 5.548 1.00 0.00 ATOM 799 O ASP 167 3.795 0.382 4.620 1.00 0.00 ATOM 800 N TYR 168 2.279-0.844 5.721 1.00 0.00 ATOM 801 H TYR 168 2.103-1.428 6.487 1.00 0.00 ATOM 802 CA TYR 168 1.179-0.503 4. 818 1.00 0.00 ATOM 803 HA TYR 168 1.602-0.241 3.851 1.00 0.00 ATOM 804 CB TYR 168 0.233-1.696 4.647 1.00 0. 00 ATOM 805 1HB TYR 168 0.709-2.433 4.022 1.00 0.00 ATOM 806 2HB TYR 168-0.673-1.358 4.168 1.00 0.00 ATOM 807 QB TYR 168 0.018-1.896 4. 095 1.00 0.00 ATOM 808 QD TYR 168-0. 198-2.438 6.106 1.00 0.00 ATOM 809 QE TYR 168-0.826-3.500 8.231 1.00 0.00 ATOM 810 QR TYR 168-0.512-2.969 7.169 1.00 0.00 ATOM 811 CG TYR 168-0.154-2.361 5.953 1.00 0.00 ATOM 812 CD1 TYR 168-1.370-2.078 6.562 1.00 0.00 ATOM 813 1HD TYR 168-2. 044-1.380 6.088 1.00 0.00 ATOM 814 CE1 TYR 168-1.726-2.673 7.757 1.00 0. 00 ATOM 815 1HE TYR 168-2.676-2.440 8.215 1.00 0.00 ATOM 816 CZ TYR 168-0.863-3.563 8.359 1.00 0.00 ATOM 817 CE2 TYR 168 0.349-3.863 7. 775 1.00 0.00 ATOM 818 2HE TYR 168 1.025-4.560 8. 247 1.00 0.00

ATOM 819 CD2 TYR 168 0.698-3.264 6.581 1.00 0.00 ATOM 820 2HD TYR 168 1.649-3.496 6.123 1.00 0.00 ATOM 821 OH TYR 168-1.216-4.159 9.545 1.00 0.00 ATOM 822 HH TYR 168-0.594-3.902 10.232 1.00 0.00 ATOM 823 C TYR 168 0.398 0.697 5.343 1.00 0.00 ATOM 824 O TYR 168 0.339 0.940 6.547 1.00 0.00 ATOM 825 N GLY 169-0.213 1.423 4.428 1.00 0.00 ATOM 826 H GLY 169-0.137 1.165 3.484 1.00 0.00 ATOM 827 CA GLY 169-1.001 2.582 4.785 1.00 0.00 ATOM 828 1HA GLY 169-0.370 3.460 4.766 1.00 0.00 ATOM 829 2HA GLY 169-1.397 2.450 5.781 1.00 0.00 ATOM 830 QA GLY 169-0.884 2.955 5.274 1.00 0.00 ATOM 831 C GLY 169-2.135 2.770 3.814 1.00 0.00 ATOM 832 O GLY 169-2.062 2.288 2.683 1.00 0.00 ATOM 833 N MET 170-3.186 3.447 4.235 1.00 0.00 ATOM 834 H MET 170-3.196 3.806 5.147 1.00 0.00 ATOM 835 CA MET 170-4.330 3.669 3.368 1.00 0.00 ATOM 836 HA MET 170-4.003 3.509 2.345 1.00 0.00 ATOM 837 CB MET 170-5.451 2.682 3.701 1.00 0. 00 ATOM 838 1HB MET 170-6.384 3.075 3.323 1.00 0.00 ATOM 839 2HB MET 170-5.522 2.582 4.774 1.00 0.00 ATOM 840 QB MET 170-5.953 2.828 4.049 1.00 0.00 ATOM 841 CG MET 170-5.238 1.301 3.104 1.00 0.00 ATOM 842 1HG MET 170-4. 620 1.397 2.222 1.00 0.00 ATOM 843 2HG MET 170-6.198 0.893 2.824 1.00 0.00 ATOM 844 QG MET 170-5.409 1.145 2.523 1.00 0.00 ATOM 845 SD MET 170-4.440 0.159 4.247 1.00 0.00 ATOM 846 QE MET 170-2.986-0.780 2.973 1.00 0.00 ATOM 847 CE MET 170-3.230-0.623 3.186 1.00 0.00 ATOM 848 1HE MET 170-3.734-1.132 2.378 1.00 0.00 ATOM 849 2HE MET 170-2.656-1.337 3.759 1.00 0.00 ATOM 850 3HE MET 170-2.568 0.129 2.781 1.00 0.00 ATOM 851 C MET 170-4.826 5.099 3.509 1.00 0.00 ATOM 852 0 MET 170-5.236 5.521 4.591 1.00 0.00 ATOM 853 N LEU 171-4.766 5.845 2.418 1.00 0.00 ATOM 854 H LEU 171-4.413 5.451 1.590 1.00 0.00 ATOM 855 CA LEU 171-5.186 7.240 2.424 1.00 0.00 ATOM 856 HA LEU 171-5.397 7.513 3.447 1.00 0.00 ATOM 857 CB LEU 171-4.058 8.127 1.900 1.00 0.00 ATOM 858 1HB LEU 171-4.195 9.121 2.296 1.00 0.00 ATOM 859 2HB LEU 171-4.133 8.173 0.821 1.00 0.00 ATOM 860 QB LEU 171-4.164 8.647 1.559 1.00 0.00 ATOM 861 CG LEU 171-2.651 7.659 2.263 1.00 0.00 ATOM 862 HG LEU 171-2.715 6. 910 3.040 1.00 0.00 ATOM 863 QD1 LEU 171-1.812 6.881 0.773 1.00 0.00 ATOM 864 QD2 LEU 171-1.634 9.094 2.921 1.00 0.00 ATOM 865 CD1 LEU 171-1.974 7.030 1.058 1.00 0.00 ATOM 866 1HD1 LEU 171-2.235 5.984 1.003 1.00 0.00 ATOM 867 2HD1 LEU 171-0.902 7.128 1.158 1.00 0.00 ATOM 868 3HD1 LEU 171-2.299 7.532 0.158 1.00 0.00 ATOM 869 CD2 LEU 171-1.829 8.820 2.795 1.00 0.00 ATOM 870 1HD2 LEU 171-0.890 8.448 3.180 1.00 0.00 ATOM 871 2HD2 LEU 171-2.372 9.314 3.586 1.00 0.00 ATOM 872 3HD2 LEU 171-1.638 9.521 1.995 1.00 0.00 ATOM 873 QQD LEU 171-1.723 7.988 1.847 1.00 0.00 ATOM 874 C LEU 171-6.442 7.458 1.590 1.00 0.00 ATOM 875 O LEU 171-7.175 6.510 1.299 1.00 0.00 ATOM 876 N LEU 172-6.660 8.726 1.214 1.00 0.00 ATOM 877 H LEU 172-6.012 9.406 1.489 1.00 0.00 ATOM 878 CA LEU 172-7.808 9.155 0.405 1.00 0.00 ATOM 879 HA LEU 172-7.958 10.207 0.597 1.00 0.00 ATOM 880 CB LEU 172-7.504 8.979-1.082 1.00 0.00 ATOM 881 1HB LEU 172-8.345 8.482-1.543 1.00 0.00 ATOM 882 2HB LEU 172-6.634 8.343-1.179 1.00 0.00 ATOM 883 QB LEU 172-7.490 8.412-1.361 1.00 0.00 ATOM 884 CG LEU 172-7.239 10.279-1.843 1.00 0.00 ATOM 885 HG LEU 172-7.086 10.052-2.886 1.00 0.00 ATOM 886 QD1 LEU 172-8.714 11.437-1.709 1.00 0.00 ATOM 887 QD2 LEU 172-5.687 11.121-1.198 1.00 0.00 ATOM 888 CD1 LEU 172-8.432 11.215-1.734 1.00 0.00 ATOM 889 1HD1 LEU 172-8.956 11.241-2.679 1.00 0.00 ATOM 890 2HD1 LEU 172-8.087 12.208-1.487 1.00 0.00

ATOM 891 3HD1 LEU 172-9.098 10.863-0.962 1.00 0.00 ATOM 892 CD2 LEU 172-5.985 10.960-1.321 1.00 0.00 ATOM 893 1HD2 LEU 172-5.117 10.541-1.811 1.00 0.00 ATOM 894 2HD2 LEU 172-5.906 10.804-0.256 1.00 0.00 ATOM 895 3HD2 LEU 172-6.037 12.019-1.527 1.00 0. 00 ATOM 896 QQD LEU 172-7.200 11.279-1.453 1.00 0.00 ATOM 897 C LEU 172-9.092 8.416 0.771 1.00 0.00 ATOM 898 O LEU 172-9.571 7.581 0.007 1.00 0.00 ATOM 899 N PRO 173-9.675 8.716 1.944 1.00 0.00 ATOM 900 CD PRO 173-9.189 9.705 2.919 1.00 0.00 ATOM 901 CA PRO 173-10. 909 8.069 2.397 1.00 0.00 ATOM 902 HA PRO 173-10.737 7.025 2.624 1.00 0.00 ATOM 903 CB PRO 173-11.279 8.820 3.684 1.00 0.00 ATOM 904 1HB PRO 173-11.070 8.194 4.540 1.00 0.00 ATOM 905 2HB PRO 173-12.330 9.069 3.666 1.00 0.00 ATOM 906 QB PRO 173-11.700 8.631 4.103 1.00 0.00 ATOM 907 CG PRO 173-10.430 10.050 3.691 1.00 0.00 ATOM 908 1HG PRO 173-10.177 10.315 4.708 1.00 0.00 ATOM 909 2HG PRO 173-10.956 10.862 3.211 1. 00 0. 00 ATOM 910 QG PRO 173-10. 567 10.588 3.960 1.00 0.00 ATOM 911 1HD PRO 173-8.445 9.270 3.570 1.00 0.00 ATOM 912 2HD PRO 173-8.796 10.580 2.421 1.00 0. 00 ATOM 913 QD PRO 173-8.621 9.925 2.996 1.00 0.00 ATOM 914 C PRO 173-12.034 8.176 1.373 1.00 0.00 ATOM 915 O PRO 173-12.218 9.213 0.732 1.00 0.00 ATOM 916 N CYS 174-12.779 7.095 1.223 1.00 0.00 ATOM 917 H CYS 174-12.577 6.300 1.767 1.00 0.00 ATOM 918 CA CYS 174-13.889 7.046 0.284 1.00 0.00 ATOM 919 HA CYS 174-13.880 7.959-0.292 1.00 0.00 ATOM 920 CB CYS 174-13.735 5.854-0.659 1.00 0.00 ATOM 921 1HB CYS 174-14.090 4.965-0.161 1.00 0.00 ATOM 922 2HB CYS 174-12.691 5.730-0.905 1.00 0.00 ATOM 923 QB CYS 174-13.391 5.347-0.533 1.00 0.00 ATOM 924 SG CYS 174-14.655 6.018-2.223 1.00 0.00 ATOM 925 C CYS 174-15.206 6.947 1.036 1.00 0.00 ATOM 926 O CYS 174-16.214 7.514 0.624 1.00 0.00 ATOM 927 N GLY 175-15.178 6.233 2.149 1.00 0.00 ATOM 928 H GLY 175-14.335 5.815 2.433 1.00 0. 00 ATOM 929 CA GLY 175-16.361 6.074 2.966 1.00 0.00 ATOM 930 1HA GLY 175-16.823 5.125 2.743 1.00 0.00 ATOM 931 2HA GLY 175-17.058 6.869 2.743 1.00 0.00 ATOM 932 QA GLY 175-16.941 5.997 2.743 1.00 0. 00 ATOM 933 C GLY 175-16.013 6.120 4.432 1.00 0.00 ATOM 934 O GLY 175-14.996 6.700 4.806 1.00 0.00 ATOM 935 N ILE 176-16.840 5.504 5.259 1.00 0. 00 ATOM 936 H ILE 176-17.629 5.050 4.901 1.00 0.00 ATOM 937 CA ILE 176-16.592 5.473 6.692 1.00 0.00 ATOM 938 HA ILE 176-16.330 6.472 7.011 1.00 0.00 ATOM 939 CB ILE 176-17.848 5.020 7.469 1.00 0.00 ATOM 940 HB ILE 176-17.896 3.944 7.425 1.00 0.00 ATOM 941 QG2 ILE 176-17.729 5.530 9.276 1.00 0.00 ATOM 942 CG2 ILE 176-17.752 5.433 8.930 1.00 0.00 ATOM 943 1HG2 ILE 176-17.901 6.499 9.013 1.00 0.00 ATOM 944 2HG2 ILE 176-16.775 5.175 9.314 1.00 0.00 ATOM 945 3HG2 ILE 176-18.511 4.918 9.500 1.00 0.00 ATOM 946 CG1 ILE 176-19.114 5. 603 6.834 1.00 0.00 ATOM 947 1HG1 ILE 176-19.176 5.281 5.806 1.00 0.00 ATOM 948 2HG1 ILE 176-19.062 6.681 6.867 1.00 0.00 ATOM 949 QG1 ILE 176-19. 119 5.981 6.337 1.00 0.00 ATOM 950 QD1 ILE 176-20.693 5.080 7.698 1.00 0.00 ATOM 951 CD1 ILE 176-20.390 5.181 7.532 1.00 0.00 ATOM 952 1HD1 ILE 176-20.782 4.293 7.059 1.00 0.00 ATOM 953 2HD1 ILE 176-21.117 5.976 7.465 1.00 0.00 ATOM 954 3HD1 ILE 176-20.178 4.972 8.570 1.00 0.00 ATOM 955 C ILE 176-15.431 4.528 7.009 1.00 0.00 ATOM 956 O ILE 176-14.640 4.776 7.918 1.00 0.00 ATOM 957 N ASP 177-15.349 3.441 6.249 1.00 0.00 ATOM 958 H ASP 177-16.017 3.301 5.549 1.00 0.00 ATOM 959 CA ASP 177-14.302 2.439 6.432 1.00 0.00 ATOM 960 HA ASP 177-13.625 2.785 7.197 1.00 0.00 ATOM 961 CB ASP 177-14.930 1.113 6. 872 1.00 0.00 ATOM 962 1HB ASP 177-15.629 1.298 7.674 1.00 0.00

ATOM 963 2HB ASP 177-14.153 0.450 7.220 1.00 0.00 ATOM 964 QB ASP 177-14.891 0.874 7.447 1.00 0.00 ATOM 965 CG ASP 177-15.670 0.432 5.736 1.00 0.00 ATOM 966 OD1 ASP 177-15.312-0.714 5.383 1.00 0.00 ATOM 967 OD2 ASP 177-16.601 1.050 5. 173 1.00 0.00 ATOM 968 C ASP 177-13.529 2.201 5.136 1.00 0.00 ATOM 969 O ASP 177-12.562 1.435 5. 106 1.00 0.00 ATOM 970 N LYS+ 178-13.980 2.824 4. 056 1.00 0.00 ATOM 971 H LYS+ 178-14.767 3.398 4.132 1.00 0.00 ATOM 972 CA LYS+ 178-13.348 2.639 2.756 1.00 0.00 ATOM 973 HA LYS+ 178-12.804 1.707 2.788 1.00 0.00 ATOM 974 CB LYS+ 178-14.412 2.551 1.658 1.00 0.00 ATOM 975 1HB LYS+ 178-13.930 2.280 0.729 1.00 0.00 ATOM 976 2HB LYS+ 178-14.874 3.520 1. 544 1.00 0.00 ATOM 977 QB LYS+ 178-14.402 2.900 1.137 1.00 0.00 ATOM 978 CG LYS+ 178-15.506 1.529 1.948 1.00 0.00 ATOM 979 1HG LYS+ 178-16.334 1.699 1.275 1.00 0.00 ATOM 980 2HG LYS+ 178-15.838 1.653 2.970 1.00 0.00 ATOM 981 QG LYS+ 178-16.086 1.676 2.123 1.00 0. 00 ATOM 982 CD LYS+ 178-15.003 0.104 1.767 1.00 0.00 ATOM 983 1HD LYS+ 178-14.254-0.101 2.519 1.00 0.00 ATOM 984 2HD LYS+ 178-14.562 0.011 0.784 1.00 0.00 ATOM 985 QD LYS+ 178-14.408-0.045 1.652 1.00 0.00 ATOM 986 CE LYS+ 178-16.126-0.916 1.898 1.00 0.00 ATOM 987 1HE LYS+ 178-15.701-1.908 1.832 1.00 0.00 ATOM 988 2HE LYS+ 178-16.824-0.772 1.086 1.00 0.00 ATOM 989 QE LYS+ 178-16.263-1.340 1.459 1.00 0.00 ATOM 990 NZ LYS+ 178-16.854-0.787 3.191 1.00 0.00 ATOM 991 1HZ LYS+ 178-17.518-1.574 3.315 1.00 0. 00 ATOM 992 2HZ LYS+ 178-17.383 0.107 3.225 1.00 0.00 ATOM 993 3HZ LYS+ 178-16.175-0.792 3.995 1.00 0.00 ATOM 994 QZ LYS+ 178-17.026-0.753 3.512 1.00 0.00 ATOM 995 C LYS+ 178-12.356 3.742 2.437 1.00 0.00 ATOM 996 0 LYS+ 178-12.558 4.903 2.786 1.00 0.00 ATOM 997 N PHE 179-11.288 3.357 1.752 1.00 0.00 ATOM 998 H PHE 179-11.204 2.412 1.496 1.00 0.00 ATOM 999 CA PHE 179-10.240 4.277 1.356 1.00 0.00 ATOM 1000 HA PHE 179-10.547 5.280 1.609 1.00 0.00 ATOM 1001 CB PHE 179-8.934 3.947 2.075 1.00 0.00 ATOM 1002 1HB PHE 179-8.214 4.699 1.831 1.00 0.00 ATOM 1003 2HB PHE 179-8.567 2.997 1.722 1.00 0.00 ATOM 1004 QB PHE 179-8. 391 3.848 1.777 1.00 0.00 ATOM 1005 QD PHE 179-9.060 3.870 3.738 1.00 0.00 ATOM 1006 QE PHE 179-9.244 3.762 6.188 1.00 0. 00 ATOM 1007 QR PHE 179-9.189 3.794 5.454 1.00 0. 00 ATOM 1008 CG PHE 179-9.047 3.878 3.572 1.00 0. 00 ATOM 1009 CD1 PHE 179-8.829 5.005 4.346 1.00 0.00 ATOM 1010 1HD PHE 179-8.577 5.938 3.865 1.00 0.00 ATOM 1011 CE1 PHE 179-8.932 4.947 5.722 1.00 0. 00 ATOM 1012 1HE PHE 179-8.759 5.833 6.315 1.00 0.00 ATOM 1013 CZ PHE 179-9.254 3.755 6.340 1.00 0.00 ATOM 1014 HZ PHE 179-9.336 3.708 7.417 1.00 0.00 ATOM 1015 CE2 PHE 179-9.474 2.623 5.580 1.00 0.00 ATOM 1016 2HE PHE 179-9.728 1.691 6.060 1.00 0.00 ATOM 1017 CD2 PHE 179-9.369 2.687 4.204 1.00 0.00 ATOM 1018 2HD PHE 179-9.542 1.802 3.610 1.00 0.00 ATOM 1019 C PHE 179-9.999 4.179-0.136 1.00 0.00 ATOM 1020 O PHE 179-10.669 3.418-0.830 1.00 0.00 ATOM 1021 N ARG+ 180-9.020 4.930-0.613 1.00 0.00 ATOM 1022 H ARG+ 180-8.515 5.502 0.008 1.00 0.00 ATOM 1023 CA ARG+ 180-8.651 4.917-2.023 1.00 0.00 ATOM 1024 HA ARG+ 180-9.027 4.002-2.460 1.00 0.00 ATOM 1025 CB ARG+ 180-9.255 6.111-2.769 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.916 6.076-3.796 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.901 7.022-2.319 1.00 0.00 ATOM 1028 QB ARG+ 180-8. 909 6.549-3.057 1.00 0.00 ATOM 1029 CG ARG+ 180-10.771 6.133-2. 775 1. 00 0. 00 ATOM 1030 1HG ARG+ 180-11.125 6.083-1.756 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.130 5.275-3.326 1.00 0.00 ATOM 1032 QG ARG+ 180-11.128 5.679-2.541 1.00 0.00 ATOM 1033 CD ARG+ 180-11.304 7.396-3. 426 1.00 0.00 ATOM 1034 1HD ARG+ 180-12.142 7.132-4.055 1.00 0.00

ATOM 1035 2HD ARG+ 180-10.522 7.832-4.032 1.00 0.00 ATOM 1036 QD ARG+ 180-11. 332 7.482-4.043 1.00 0.00 ATOM 1037 NE ARG+ 180-11.742 8.379-2.436 1.00 0.00 ATOM 1038 HE ARG+ 180-11.279 8.383-1.566 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.723 9.253-2.650 1.00 0.00 ATOM 1040 NH1 ARG+ 180-13.347 9.276-3.823 1.00 0.00 ATOM 1041 lHH1 ARG+ 180-13.078 8.636-4.546 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-14.086 9.928-3.990 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13. 582 9.282-4.268 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13. 079 10.101-1.691 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.608 10.080-0.801 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.814 10.761-1.848 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13.211 10.420-1.324 1.00 0.00 ATOM 1048 C ARG+ 180-7.134 4.947-2. 171 1.00 0.00 ATOM 1049 O ARG+ 180-6.600 4.626-3.223 1.00 0.00 ATOM 1050 N GLY 181-6.439 5.339-1.116 1.00 0.00 ATOM 1051 H GLY 181-6.906 5.584-0.287 1.00 0.00 ATOM 1052 CA GLY 181-4.992 5.412-1.182 1.00 0.00 ATOM 1053 1HA GLY 181-4. 667 6.338-0.729 1.00 0.00 ATOM 1054 2HA GLY 181-4.694 5.411-2.220 1.00 0.00 ATOM 1055 QA GLY 181-4. 681 5.874-1.474 1.00 0.00 ATOM 1056 C GLY 181-4. 313 4.260-0.482 1.00 0.00 ATOM 1057 O GLY 181-4. 872 3.672 0.442 1.00 0.00 ATOM 1058 N VAL 182-3.103 3.937-0.925 1.00 0.00 ATOM 1059 H VAL 182-2.718 4.451-1.662 1.00 0.00 ATOM 1060 CA VAL 182-2. 328 2.847-0.343 1.00 0.00 ATOM 1061 HA VAL 182-2.654 2.711 0.681 1.00 0.00 ATOM 1062 CB VAL 182-2.518 1.510-1.110 1.00 0.00 ATOM 1063 HB VAL 182-1. 729 1.435-1.846 1.00 0.00 ATOM 1064 QG1 VAL 182-2.353 0.047 0.058 1.00 0.00 ATOM 1065 QG2 VAL 182-4.170 1.440-2.012 1.00 0.00 ATOM 1066 CG1 VAL 182-2.384 0.328-0.166 1.00 0.00 ATOM 1067 1HG1 VAL 182-3.195-0.364-0.339 1.00 0.00 ATOM 1068 2HG1 VAL 182-2.420 0.677 0.856 1.00 0.00 ATOM 1069 3HG1 VAL 182-1.442-0.170-0.343 1.00 0.00 ATOM 1070 CG2 VAL 182-3.853 1.453-1.840 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.833 2.129-2.682 1.00 0.00 ATOM 1072 2HG2 VAL 182-4. 645 1.745-1.165 1.00 0.00 ATOM 1073 3HG2 VAL 182-4.032 0.447-2.189 1.00 0.00 ATOM 1074 QQG VAL 182-3.261 0.744-0.977 1.00 0.00 ATOM 1075 C VAL 182-0.837 3.185-0.350 1. OO 0.00 ATOM 1076 O VAL 182-0.273 3.495-1.400 1.00 0.00 ATOM 1077 N GLU 183-0.205 3.107 0.817 1.00 0.00 ATOM 1078 H GLU 183-0.714 2.842 1.618 1.00 0.00 ATOM 1079 CA GLU 183 1.225 3.385 0.947 1.00 0.00 ATOM 1080 HA GLU 183 1.650 3.420-0.047 1.00 0.00 ATOM 1081 CB GLU 183 1.454 4.729 1.641 1.00 0.00 ATOM 1082 1HB GLU 183 1.469 5.509 0.894 1.00 0.00 ATOM 1083 2HB GLU 183 2.413 4.704 2.138 1.00 0.00 ATOM 1084 QB GLU 183 1.941 5.106 1.516 1.00 0.00 ATOM 1085 CG GLU 183 0.400 5.083 2.674 1.00 0.00 ATOM 1086 1HG GLU 183 0.153 4.196 3.237 1.00 0.00 ATOM 1087 2HG GLU 183-0.480 5.445 2.165 1.00 0.00 ATOM 1088 QG GLU 183-0.164 4.820 2.701 1.00 0.00 ATOM 1089 CD GLU 183 0.874 6.149 3.635 1.00 0.00 ATOM 1090 OE1 GLU 183 1.950 6.737 3.384 1.00 0.00 ATOM 1091 OE2 GLU 183 0.170 6.400 4.632 1.00 0.00 ATOM 1092 C GLU 183 1.899 2.268 1.736 1.00 0.00 ATOM 1093 O GLU 183 1.843 2.238 2.957 1.00 0.00 ATOM 1094 N PHE 184 2.499 1.323 1.037 1.00 0.00 ATOM 1095 H PHE 184 2.490 1.371 0.064 1.00 0.00 ATOM 1096 CA PHE 184 3.127 0.183 1.693 1.00 0.00 ATOM 1097 HA PHE 184 2.998 0.311 2.755 1.00 0.00 ATOM 1098 CB PHE 184 2.438-1.118 1.270 1.00 0.00 ATOM 1099 1HB PHE 184 1.536-1.252 1.849 1.00 0.00 ATOM 1100 2HB PHE 184 3. 106-1. 944 1.474 1.00 0.00 ATOM 1101 QB PHE 184 2.321-1.598 1.662 1.00 0.00 ATOM 1102 QD PHE 184 2.029-1.189-0.363 1.00 0.00 ATOM 1103 QE PHE 184 1.423-1.348-2.739 1.00 0.00 ATOM 1104 QR PHE 184 1.604-1.303-2.026 1.00 0.00 ATOM 1105 CG PHE 184 2.072-1. 183-0.196 1.00 0.00 ATOM 1106 CD1 PHE 184 1.055-0.397-0.723 1.00 0.00

ATOM 1107 1HD PHE 184 0.528 0.290-0.077 1.00 0.00 ATOM 1108 CE1 PHE 184 0.711-0. 485-2.059 1.00 0.00 ATOM 1109 1HE PHE 184-0.081 0.132-2.455 1.00 0.00 ATOM 1110 CZ PHE 184 1.385-1.361-2.886 1.00 0.00 ATOM 1111 HZ PHE 184 1.115-1. 441-3.928 1.00 0.00 ATOM 1112 CE2 PHE 184 2.398-2.142-2.377 1.00 0.00 ATOM 1113 2HE PHE 184 2.928-2. 828-3.023 1.00 0.00 ATOM 1114 CD2 PHE 184 2.735-2.053-1.042 1.00 0.00 ATOM 1115 2HD PHE 184 3.531-2. 668-0.650 1.00 0.00 ATOM 1116 C PHE 184 4.613 0.063 1.393 1.00 0.00 ATOM 1117 O PHE 184 5.056 0.297 0.275 1.00 0.00 ATOM 1118 N VAL 185 5.371-0. 345 2.401 1.00 0.00 ATOM 1119 H VAL 185 4.949-0.538 3.266 1.00 0.00 ATOM 1120 CA VAL 185 6.802-0.546 2.258 1.00 0.00 ATOM 1121 HA VAL 185 7.104-0.164 1.291 1.00 0.00 ATOM 1122 CB VAL 185 7.611 0.188 3.354 1.00 0.00 ATOM 1123 HB VAL 185 7.695-0.470 4.212 1.00 0.00 ATOM 1124 QG1 VAL 185 9.344 0.585 2.751 1.00 0.00 ATOM 1125 QG2 VAL 185 6.739 1.758 3.907 1.00 0.00 ATOM 1126 CG1 VAL 185 9.013 0.509 2.864 1. 00 0.00 ATOM 1127 1HG1 VAL 185 9.147 1.580 2.843 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.150 0.107 1.872 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.735 0.069 3.536 1.00 0.00 ATOM 1130 CG2 VAL 185 6.907 1.458 3.800 1.00 0.00 ATOM 1131 1HG2 VAL 185 7.222 2.283 3.179 1.00 0.00 ATOM 1132 2HG2 VAL 185 7.158 1.664 4.830 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.838 1.328 3.711 1.00 0.00 ATOM 1134 QQG VAL 185 8.041 1.172 3.329 1.00 0.00 ATOM 1135 C VAL 185 7.124-2.033 2.321 1.00 0.00 ATOM 1136 O VAL 185 7.092-2.643 3.388 1.00 0.00 ATOM 1137 N CYS 186 7.437-2.620 1.178 1.00 0.00 ATOM 1138 H CYS 186 7.452-2.090 0.349 1.00 0.00 ATOM 1139 CA CYS 186 7.775-4.030 1.134 1.00 0.00 ATOM 1140 HA CYS 186 7.562-4.443 2.112 1.00 0.00 ATOM 11. 41 CB CYS 186 6.941-4.777 0.086 1.00 0.00 ATOM 1142 1HB CYS 186 5.951-4.948 0.486 1.00 0.00 ATOM 1143 2HB CYS 186 7.406-5.729-0.115 1.00 0.00 ATOM 1144 QB CYS 186 6.678-5.339 0.186 1.00 0.00 ATOM 1145 SG CYS 186 6.752-3.921-1.506 1.00 0.00 ATOM 1146 C CYS 186 9.261-4.189 0.857 1.00 0.00 ATOM 1147 O CYS 186 9.781-3.644-0.109 1.00 0.00 ATOM 1148 N CYS 187 9.956-4.910 1.717 1.00 0.00 ATOM 1149 H CYS 187 9.501-5.318 2.487 1.00 0.00 ATOM 1150 CA CYS 187 11.393-5.091 1.552 1.00 0.00 ATOM 1151 HA CYS 187 11.766-4.256 0.978 1.00 0.00 ATOM 1152 CB CYS 187 12.076-5.094 2.920 1.00 0.00 ATOM 1153 1HB CYS 187 13.144-5.013 2.782 1.00 0.00 ATOM 1154 2HB CYS 187 11.852-6.022 3.425 1.00 0.00 ATOM 1155 QB CYS 187 12.498-5.518 3.104 1.00 0.00 ATOM 1156 SG CYS 187 11.548-3.727 4.005 1.00 0.00 ATOM 1157 C CYS 187 11.705-6. 377 0.806 1.00 0.00 ATOM 1158 O CYS 187 11.034-7.384 1.002 1.00 0.00 ATOM 1159 N PRO 188 12.720-6.348-0.078 1.00 0.00 ATOM 1160 CD PRO 188 13.547-5.171-0.393 1.00 0.00 ATOM 1161 CA PRO 188 13.117-7.520-0.868 1.00 0.00 ATOM 1162 HA PRO 188 12.322-7.836-1.530 1.00 0.00 ATOM 1163 CB PRO 188 14.305-7.021-1.696 1.00 0.00 ATOM 1164 1HB PRO 188 14.246-7.430-2.694 1.00 0.00 ATOM 1165 2HB PRO 188 15.227-7.336-1.228 1.00 0.00 ATOM 1166 QB PRO 188 14.736-7.383-1.961 1.00 0.00 ATOM 1167 CG PRO 188 14.175-5.537-1.707 1.00 0.00 ATOM 1168 1HG PRO 188 13.539-5.231-2.526 1.00 0.00 ATOM 1169 2HG PRO 188 15.150-5.082-1.799 1.00 0.00 ATOM 1170 QG PRO 188 14.344-5.157-2.162 1.00 0.00 ATOM 1171 1HD PRO 188 12.934-4.288-0.501 1.00 0.00 ATOM 1172 2HD PRO 188 14.306-5.017 0.359 1.00 0.00 ATOM 1173 QD PRO 188 13.620-4.653-0.071 1.00 0.00 ATOM 1174 C PRO 188 13.539-8.699 0.002 1. 00 0. 00 ATOM 1175 0 PRO 188 14.407-8.561 0.872 1.00 0.00 ATOM 1176 N LEU 189 12.920-9.844-0.251 1.00 0.00 ATOM 1177 H LEU 189 12.245-9.868-0.964 1.00 0.00 ATOM 1178 CA LEU 189 13.207-11.070 0.473 1.00 0.00

ATOM 1179 HA LEU 189 14.041-10.883 1.133 1.00 0.00 ATOM 1180 CB LEU 189 11.993-11.502 1.300 1.00 0.00 ATOM 1181 1HB LEU 189 11.235-11.861 0.620 1.00 0.00 ATOM 1182 2HB LEU 189 11.609-10.637 1.818 1.00 0.00 ATOM 1183 QB LEU 189 11.422-11.249 1.219 1.00 0.00 ATOM 1184 CG LEU 189 12.268-12.600 2.329 1.00 0.00 ATOM 1185 HG LEU 189 13.076-13.223 1.972 1.00 0.00 ATOM 1186 QD1 LEU 189 12.792-11.852 3.971 1.00 0.00 ATOM 1187 QD2 LEU 189 10.749-13.685 2.556 1.00 0. 00 ATOM 1188 CD1 LEU 189 12.692-11.995 3.657 1.00 0.00 ATOM 1189 1HD1 LEU 189 13.613-11.447 3.524 1.00 0.00 ATOM 1190 2HD1 LEU 189 12.843-12.783 4.379 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.922-11.325 4. 009 1.00 0.00 ATOM 1192 CD2 LEU 189 11.040-13.477 2.513 1.00 0.00 ATOM 1193 1HD2 LEU 189 10.635-13.735 1.545 1.00 0.00 ATOM 1194 2HD2 LEU 189 10.297-12.940 3.083 1.00 0.00 ATOM 1195 3HD2 LEU 189 11.317-14.378 3.039 1.00 0.00 ATOM 1196 QQD LEU 189 11.771-12.768 3.263 1.00 0.00 ATOM 1197 C LEU 189 13.585-12.174-0.509 1.00 0.00 ATOM 1198 OT1 LEU 189 14.374-13.062-0.129 1.00 0. 00 ATOM 1199 OT2 LEU 189 13.086-12.135-1.655 1.00 0.00 TER ENDMDL MODEL 10 ATOM 1 N SER 124 7.388 16.131 3.577 1.00 0.00 ATOM 2 CA SER 124 7.269 16.327 2.109 1.00 0.00 ATOM 3 HA SER 124 6.602 15.579 1.706 1.00 0.00 ATOM 4 CB SER 124 6.692 17.720 1.861 1.00 0.00 ATOM 5 1HB SER 124 5.927 17.663 1.099 1.00 0.00 ATOM 6 2HB SER 124 7.483 18.380 1.529 1.00 0.00 ATOM 7 QB SER 124 6.705 18.022 1.314 1.00 0.00 ATOM 8 OG SER 124 6.119 13. 246 3.052 1.00 0.00 ATOM 9 HG SER 124 5.841 19.158 2.900 1.00 0.00 ATOM 10 C SER 124 8.632 16.187 1.461 1.00 0.00 ATOM 11 O SER 124 9.099 17.076 0.749 1.00 0.00 ATOM 12 1HT SER 124 8.385 15.939 3.834 1.00 0.00 ATOM 13 2HT SER 124 6.803 15.331 3.884 1.00 0.00 ATOM 14 3HT SER 124 7.075 16.990 4.074 1.00 0.00 ATOM 15 N ASP 125 9.272 15.073 1.759 1.00 0.00 ATOM 16 H ASP 125 8.846 14.427 2.359 1.00 0.00 ATOM 17 CA ASP 125 10.605 14.785 1.272 1.00 0.00 ATOM 18 HA ASP 125 10.910 15.585 0.615 1.00 0.00 ATOM 19 CB ASP 125 11.559 14.716 2.468 1.00 0.00 ATOM 20 1HB ASP 125 12.082 15.656 2.564 1. 00 0.00 ATOM 21 2HB ASP 125 12.274 13.923 2.307 1.00 0.00 ATOM 22 QB ASP 125 12.178 14.790 2.436 1.00 0.00 ATOM 23 CG ASP 125 10.817 14.441 3.765 1.00 0. 00 ATOM 24 OD1 ASP 125 10.859 13.289 4.233 1.00 0.00 ATOM 25 OD2 ASP 125 10. 156 15.370 4.290 1.00 0. 00 ATOM 26 C ASP 125 10.615 13.470 0.510 1.00 0.00 ATOM 27 O ASP 125 10.632 13.450-0.720 1.00 0.00 ATOM 28 N ALA 126 10.592 12.370 1.248 1.00 0.00 ATOM 29 H ALA 126 10.571 12.450 2.229 1.00 0.00 ATOM 30 CA ALA 126 10. 591 11.050 0.640 1.00 0.00 ATOM 31 HA ALA 126 10.907 11.158-0.387 1.00 0.00 ATOM 32 QB ALA 126 11.814 9.921 1.518 1.00 0.00 ATOM 33 CB ALA 126 11.581 10.137 1.349 1.00 0.00 ATOM 34 1HB ALA 126 11.959 9.404 0.652 1.00 0.00 ATOM 35 2HB ALA 126 11.083 9.634 2.166 1.00 0.00 ATOM 36 3HB ALA 126 12.401 10.725 1.735 1.00 0.00 ATOM 37 C ALA 126 9.199 10.437 0. 667 1.00 0.00 ATOM 38 O ALA 126 8.554 10.374 1.712 1.00 0.00 ATOM 39 N LEU 127 8.747 9.982-0.489 1.00 0.00 ATOM 40 H LEU 127 9.312 10.060-1.282 1.00 0.00 ATOM 41 CA LEU 127 7.439 9.359-0.618 1.00 0.00 ATOM 42 HA LEU 127 7.069 9.148 0.373 1.00 0.00 ATOM 43 CB LEU 127 6.471 10.302-1.335 1.00 0.00 ATOM 44 1HB LEU 127 6.550 10.119-2.397 1.00 0.00 ATOM 45 2HB LEU 127 6.779 11.319-1.138 1.00 0. 00 ATOM 46 QB LEU 127 6.665 10.719-1.767 1.00 0.00 ATOM 47 CG LEU 127 5.002 10.156-0.933 1.00 0.00 ATOM 48 HG LEU 127 4.820 9.136-0.621 1.00 0.00

ATOM 49 QD1 LEU 127 4.595 11.285 0.513 1.00 0.00 ATOM 50 QD2 LEU 127 3.881 10.525-2.395 1.00 0.00 ATOM 51 CD1 LEU 127 4.674 11.069 0.236 1.00 0.00 ATOM 52 lHD1 LEU 127 4.870 10.551 1.163 1.00 0.00 ATOM 53 2HD1 LEU 127 3.631 11.346 0.192 1.00 0.00 ATOM 54 3HD1 LEU 127 5.285 11.957 0.182 1.00 0.00 ATOM 55 CD2 LEU 127 4.096 10.455-2.115 1.00 0.00 ATOM 56 1HD2 LEU 127 3.080 10.187-1.865 1.00 0.00 ATOM 57 2HD2 LEU 127 4.419 9.881-2.971 1.00 0.00 ATOM 58 3HD2 LEU 127 4.144 11.508-2.349 1.00 0.00 ATOM 59 QQD LEU 127 4.238 10.905-0.941 1.00 0.00 ATOM 60 C LEU 127 7.570 8.058-1.395 1.00 0.00 ATOM 61 O LEU 127 6.584 7.483-1.854 1.00 0.00 ATOM 62 N LEU 128 8.806 7.609-1.547 1.00 0.00 ATOM 63 H LEU 128 9.545 8.115-1.162 1.00 0.00 ATOM 64 CA LEU 128 9.089 6.389-2.275 1.00 0.00 ATOM 65 HA LEU 128 8.153 5.892-2.470 1.00 0.00 ATOM 66 CB LEU 128 9.771 6.739-3.611 1.00 0.00 ATOM 67 1HB LEU 128 10. 840 6.715-3.454 1.00 0.00 ATOM 68 2HB LEU 128 9.491 7.749-3.871 1.00 0.00 ATOM 69 QB LEU 128 10.166 7.232-3.662 1.00 0.00 ATOM 70 CG LEU 128 9.445 5.833-4.812 1.00 0.00 ATOM 71 HG LEU 128 9.050 6.446-5.612 1.00 0.00 ATOM 72 QD1 LEU 128 10.996 4.987-5.453 1.00 0.00 ATOM 73 QD2 LEU 128 8.131 4.561-4.377 1.00 0.00 ATOM 74 CD1 LEU 128 10.699 5.149-5.330 1.00 0.00 ATOM 75 lHD1 LEU 128 11.562 5.538-4.811 1.00 0.00 ATOM 76 2HD1 LEU 128 10.800 5.339-6.388 1.00 0.00 ATOM 77 3HD1 LEU 128 10.625 4.085-5.160 1.00 0.00 ATOM 78 CD2 LEU 128 8.384 4.804-4.461 1.00 0.00 ATOM 79 1HD2 LEU 128 8.136 4.228-5.340 1.00 0.00 ATOM 80 2HD2 LEU 128 7.498 5.309-4.101 1.00 0.00 ATOM 81 3HD2 LEU 128 8.759 4.145-3.692 1.00 0.00 ATOM 82 QQD LEU 128 9.563 4.774-4.915 1.00 0.00 ATOM 83 C LEU 128 9.971 5.477-1.416 1.00 0.00 ATOM 84 O LEU 128 9.956 5.582-0.191 1.00 0.00 ATOM 85 N VAL 129 10.718 4.587-2.063 1.00 0.00 ATOM 86 H VAL 129 10.669 4.560-3.041 1.00 0.00 ATOM 87 CA VAL 129 11.601 3.637-1.375 1.00 0.00 ATOM 88 HA VAL 129 10. 980 2.924-0.857 1.00 0.00 ATOM 89 CB VAL 129 12.469 2.869-2.400 1.00 0.00 ATOM 90 HB VAL 129 13.076 3.588-2.931 1.00 0. 00 ATOM 91 QG1 VAL 129 13.624 1.649-1.552 1.00 0.00 ATOM 92 QG2 VAL 129 11.384 1.982-3.652 1.00 0.00 ATOM 93 CG1 VAL 129 13.401 1.882-1.715 1.00 0.00 ATOM 94 1HG1 VAL 129 12.837 1.264-1.032 1.00 0.00 ATOM 95 2HG1 VAL 129 14.159 2.424-1.166 1.00 0.00 ATOM 96 3HG1 VAL 129 13.875 1.258-2.458 1.00 0.00 ATOM 97 CG2 VAL 129 11.590 2.151-3.413 1.00 0.00 ATOM 98 1HG2 VAL 129 10.555 2.401-3.234 1.00 0.00 ATOM 99 2HG2 VAL 129 11.728 1.085-3.314 1.00 0.00 ATOM 100 3HG2 VAL 129 11.868 2.460-4.410 1.00 0.00 ATOM 101 QQG VAL 129 12.504 1.815-2.602 1.00 0.00 ATOM 102 C VAL 129 12.516 4.327-0.354 1.00 0.00 ATOM 103 O VAL 129 13.270 5.236-0.699 1.00 0.00 ATOM 104 N PRO 130 12.448 3.894 0.924 1.00 0.00 ATOM 105 CD PRO 130 11.567 2.830 1.417 1.00 0.00 ATOM 106 CA PRO 130 13.257 4.453 1.999 1.00 0.00 ATOM 107 HA PRO 130 13.402 5.509 1.870 1.00 0.00 ATOM 108 CB PRO 130 12.401 4.209 3.247 1.00 0.00 ATOM 109 1HB PRO 130 11.866 5.113 3.495 1.00 0.00 ATOM 110 2HB PRO 130 13.044 3.935 4.071 1.00 0.00 ATOM 111 QB PRO 130 12.455 4.524 3.783 1.00 0.00 ATOM 112 CG PRO 130 11.455 3.095 2.902 1.00 0.00 ATOM 113 1HG PRO 130 10.446 3.391 3.151 1.00 0.00 ATOM 114 2HG PRO 130 11.725 2.208 3.455 1.00 0.00 ATOM 115 QG PRO 130 11.086 2.800 3.303 1.00 0.00 ATOM 116 1HD PRO 130 10.594 2.892 0.952 1.00 0.00 ATOM 117 2HD PRO 130 12.007 1.858 1.240 1.00 0.00 ATOM 118 QD PRO 130 11.301 2.375 1.096 1. 00 0. 00 ATOM 119 C PRO 130 14.627 3.782 2.130 1. 00 0. 00 ATOM 120 O PRO 130 15.564 4.116 1.410 1.00 0.00

ATOM 121 N ASP 131 14.731 2.853 3.073 1.00 0.00 ATOM 122 H ASP 131 13.948 2.656 3.617 1.00 0.00 ATOM 123 CA ASP 131 15.985 2.141 3.333 1.00 0.00 ATOM 124 HA ASP 131 16.797 2.830 3.155 1.00 0.00 ATOM 125 CB ASP 131 16.028 1.695 4.802 1.00 0.00 ATOM 126 1HB ASP 131 15.205 1.021 4.990 1.00 0.00 ATOM 127 2HB ASP 131 15.926 2.563 5.436 1.00 0.00 ATOM 128 QB ASP 131 15.566 1.792 5.213 1.00 0.00 ATOM 129 CG ASP 131 17.315 0.989 5.171 1.00 0.00 ATOM 130 OD1 ASP 131 17.241-0.131 5.713 1.00 0.00 ATOM 131 OD2 ASP 131 18.401 1.542 4.912 1.00 0.00 ATOM 132 C ASP 131 16.156 0.935 2.399 1.00 0.00 ATOM 133 O ASP 131 16.530 1.088 1.240 1.00 0.00 ATOM 134 N LYS+ 132 15.888-0.266 2.908 1.00 0.00 ATOM 135 H LYS+ 132 15.603-0.335 3.842 1.00 0.00 ATOM 136 CA LYS+ 132 16.031-1.480 2.107.1.00 0.00 ATOM 137 HA LYS+ 132 16.580-1.220 1.213 1.00 0.00 ATOM 138 CB LYS+ 132 16.809-2.547 2.875 1.00 0.00 ATOM 139 1HB LYS+ 132 16.877-3. 435 2.262 1.00 0.00 ATOM 140 2HB LYS+ 132 16.270-2.787 3.780 1.00 0.00 ATOM 141 QB LYS+ 132 16. 574-3.111 3.021 1.00 0.00 ATOM 142 CG LYS+ 132 18.214-2.120 3.253 1.00 0.00 ATOM 143 1HG LYS+ 132 18.225-1.048 3.400 1.00 0.00 ATOM 144 2HG LYS+ 132 18.889-2.384 2.454 1.00 0.00 ATOM 145 QG LYS+ 132 18.557-1.716 2.927 1.00 0.00 ATOM 146 CD LYS+ 132 18.671-2.798 4.531 1.00 0.00 ATOM 147 1HD LYS+ 132 18.806-3.853 4.341 1.00 0.00 ATOM 148 2HD LYS+ 132 17.913-2.661 5.290 1.00 0.00 ATOM 149 QD LYS+ 132 18.360-3.257 4.816 1.00 0.00 ATOM 150 CE LYS+ 132 19.979-2.209 5.026 1.00 0.00 ATOM 151 1HE LYS+ 132 20.705-2.268 4.227 1.00 0.00 ATOM 152 2HE LYS+ 132 20.323-2.789 5.869 1.00 0.00 ATOM 153 QE LYS+ 132 20.514-2.528 5.048 1.00 0.00 ATOM 154 NZ LYS+ 132 19.824-0.787 5.440 1.00 0.00 ATOM 155 1HZ LYS+ 132 20.267-0.154 4.745 1.00 0.00 ATOM 156 2HZ LYS+ 132 20.264-0.626 6.365 1.00 0.00 ATOM 157 3HZ LYS+ 132 18.803-0.535 5.509 1.00 0.00 ATOM 158 QZ LYS+ 132 19.778-0.438 5.540 1.00 0.00 ATOM 159 C LYS+ 132 14.675-2.034 1.703 1.00 0.00 ATOM 160 O LYS+ 132 14.583-3.008 0.960 1.00 0.00 ATOM 161 N CYS 133 13.622-1.408 2.193 1.00 0.00 ATOM 162 H CYS 133 13.757-0.636 2.777 1.00 0.00 ATOM 163 CA CYS 133 12.272-1.839 1.876 1.00 0.00 ATOM 164 HA CYS 133 12.307-2.888 1.621 1.00 0.00 ATOM 165 CB CYS 133 11.349-1.640 3.079 1.00 0.00 ATOM 166 1HB CYS 133 10.358-1.406 2.720 1.00 0. 00 ATOM 167 2HB CYS 133 11.712-0.811 3.662 1.00 0.00 ATOM 168 QB CYS 133 11.035-1.108 3.191 1.00 0.00 ATOM 169 SG CYS 133 11.205-3.073 4.197 1.00 0.00 ATOM 170 C CYS 133 11.751-1.053 0.681 1.00 0.00 ATOM 171 O CYS 133 12.181 0.067 0.437 1.00 0.00 ATOM 172 N LYS+ 134 10.824-1.638-0.056 1.00 0.00 ATOM 173 H LYS+ 134 10.507-2.532 0.194 1.00 0.00 ATOM 174 CA LYS+ 134 10.251-0.988-1.222 1.00 0.00 ATOM 175 HA LYS+ 134 10.951-0.241-1.566 1.00 0.00 ATOM 176 CB LYS+ 134 10.006-2.007-2.339 1.00 0.00 ATOM 177 1HB LYS+ 134 9.013-2.417-2.221 1.00 0.00 ATOM 178 2HB LYS+ 134 10.727-2.805-2.246 1.00 0. 00 ATOM 179 QB LYS+ 134 9.870-2.611-2.233 1.00 0.00 ATOM 180 CG LYS+ 134 10.116-1.425-3.741 1.00 0.00 ATOM 181 1HG LYS+ 134 11.094-0.979-3.859 1.00 0.00 ATOM 182 2HG LYS+ 134 9.355-0.670-3.868 1.00 0.00 ATOM 183 QG LYS+ 134 10.225-0.824-3.863 1.00 0.00 ATOM 184 CD LYS+ 134 9.931-2.500-4.802 1.00 0.00 ATOM 185 1HD LYS+ 134 9.573-3.402-4.324 1.00 0.00 ATOM 186 2HD LYS+ 134 10.884-2.697-5.272 1.00 0.00 ATOM 187 QD LYS+ 134 10.229-3.049-4.798 1.00 0.00 ATOM 188 CE LYS+ 134 8.931-2.078-5.870 1.00 0.00 ATOM 189 1HE LYS+ 134 7.935-2.328-5.530 1.00 0.00 ATOM 190 2HE LYS+ 134 9.145-2.623-6.779 1.00 0.00 ATOM 191 QE LYS+ 134 8.540-2.475-6.154 1.00 0.00 ATOM 192 NZ LYS+ 134 8.996-0.615-6.153 1.00 0.00

ATOM 193 1HZ LYS+ 134 8.254-0.115-5.621 1.00 0.00 ATOM 194 2HZ LYS+ 134 8.855-0.439-7.170 1.00 0.00 ATOM 195 3HZ LYS+ 134 9.923-0.238-5.874 1.00 0.00 ATOM 196 QZ LYS+ 134 9. 011-0.264-6.221 1.00 0.00 ATOM 197 C LYS+ 134 8.949-0.311-0.844 1.00 0.00 ATOM 198 O LYS+ 134 7.991-0.972-0.459 1.00 0.00 ATOM 199 N PHE 135 8.922 1.003-0.948 1.00 0.00 ATOM 200 H PHE 135 9.721 1.477-1.258 1.00 0.00 ATOM 201 CA PHE 135 7.734 1.764-0.604 1.00 0.00 ATOM 202 HA PHE 135 7.168 1.196 0. 121 1.00 0.00 ATOM 203 CB PHE 135 8.137 3.106 0.011 1.00 0.00 ATOM 204 1HB PHE 135 8.438 3.775-0.783 1.00 0.00 ATOM 205 2HB PHE 135 8.975 2.950 0. 672 1.00 0.00 ATOM 206 QB PHE 135 8.707 3.363-0.055 1.00 0.00 ATOM 207 QD PHE 135 6. 941 3.874 0.895 1.00 0.00 ATOM 208 QE PHE 135 5.204 5.018 2.207 1.00 0.00 ATOM 209 QR PHE 135 5.724 4.675 1.814 1.00 0.00 ATOM 210 CG PHE 135 7.060 3.795 0.805 1.00 0.00 ATOM 211 CD1 PHE 135 7.194 5.131 1.145 1.00 0.00 ATOM 212 1HD PHE 135 8.074 5.673 0.829 1.00 0.00 ATOM 213 CE1 PHE 135 6.220 5.777 1.881 1.00 0.00 ATOM 214 1HE PHE 135 6.338 6.819 2.140 1.00 0.00 ATOM 215 CZ PHE 135 5.096 5.088 2.287 1.00 0.00 ATOM 216 HZ PHE 135 4.331 5.590 2.864 1.00 0.00 ATOM 217 CE2 PHE 135 4.950 3.758 1.954 1.00 0.00 ATOM 218 2HE PHE 135 4.070 3.216 2.273 1.00 0.00 ATOM 219 CD2 PHE 135 5.927 3.117 1.218 1.00 0.00 ATOM 220 2HD PHE 135 5.808 2.075 0.961 1.00 0. 00 ATOM 221 C PHE 135 6.878 1.992-1.835 1.00 0.00 ATOM 222 O PHE 135 7.350 2.504-2.847 1.00 0.00 ATOM 223 N LEU 136 5.622 1. 608-1. 738 1.00 0.00 ATOM 224 H LEU 136 5.308 1.202-0.897 1.00 0.00 ATOM 225 CA LEU 136 4.684 1.771-2.826 1.00 0.00 ATOM 226 HA LEU 136 5.206 2.236-3.649 1.00 0.00 ATOM 227 CB LEU 136 4.132 0.416-3.275 1.00 0.00 ATOM 228 1HB LEU 136 3.243 0.592-3.863 1.00 0.00 ATOM 229 2HB LEU 136 3.853-0.145-2.393 1.00 0.00 ATOM 230 QB LEU 136 3.548 0.224-3.128 1.00 0.00 ATOM 231 CG LEU 136 5.097-0.437-4.106 1.00 0.00 ATOM 232 HG LEU 136 5.801 0.211-4.606 1.00 0.00 ATOM 233 QD1 LEU 136 6. 065-1.608-2.999 1.00 0.00 ATOM 234 QD2 LEU 136 4.161-1.408-5.415 1.00 0.00 ATOM 235 CD1 LEU 136 5.880-1.384-3.213 1.00 0.00 ATOM 236 1HD1 LEU 136 5.491-2.386-3.321 1.00 0.00 ATOM 237 2HD1 LEU 136 5.782-1.070-2.183 1.00 0.00 ATOM 238 3HD1 LEU 136 6.921-1.369-3.495 1.00 0. 00 ATOM 239 CD2 LEU 136 4.341-1.221-5.165 1.00 0.00 ATOM 240 1HD2 LEU 136 4.597-0.847-6.145 1.00 0.00 ATOM 241 2HD2 LEU 136 3.279-1.111-5.004 1.00 0.00 ATOM 242 3HD2 LEU 136 4.608-2.266-5.097 1.00 0.00 ATOM 243 QQD LEU 136 5.113-1.508-4.207 1.00 0.00 ATOM 244 C LEU 136 3.561 2.688-2.372 1.00 0.00 ATOM 245 O LEU 136 2.461 2.238-2.065 1.00 0.00 ATOM 246 N HIS+ 137 3.865 3.976-2.315 1.00 0.00 ATOM 247 H HIS+ 137 4.770 4.261-2.561 1.00 0.00 ATOM 248 CA HIS+ 137 2.905 4.981-1.884 1.00 0.00 ATOM 249 HA HIS+ 137 2.189 4.510-1.221 1.00 0. 00 ATOM 250 CB HIS+ 137 3.642 6.107-1. 139 1.00 0.00 ATOM 251 1HB HIS+ 137 4.257 6.647-1.844 1.00 0.00 ATOM 252 2HB HIS+ 137 4.277 5.669-0.383 1.00 0.00 ATOM 253 QB HIS+ 137 4.267 6.158-1.113 1.00 0.00 ATOM 254 CG HIS+ 137 2.744 7.097-0.459 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.768 7.813-1. 114 1.00 0.00 ATOM 256 CD2 HIS+ 137 2.671 7.469 0.837 1.00 0.00 ATOM 257 1HD HIS+ 137 1.577 7.772-2.076 1.00 0.00 ATOM 258 CE1 HIS+ 137 1.131 8.579-0.247 1.00 0.00 ATOM 259 NE2 HIS+ 137 1.656 8.388 0.953 1.00 0.00 ATOM 260 2HD HIS+ 137 3.296 7.105 1.642 1.00 0.00 ATOM 261 1HE HIS+ 137 0.313 9.246-0.476 1.00 0.00 ATOM 262 2HE HIS+ 137 1.178 8.570 1.797 1.00 0.00 ATOM 263 C HIS+ 137 2.188 5.551-3.098 1.00 0.00 ATOM 264 O HIS+ 137 2.691 6.468-3.748 1.00 0.00

ATOM 265 N GLN 138 1.023 5.007-3.414 1.00 0.00 ATOM 266 H GLN 138 0.660 4.270-2.862 1.00 0.00 ATOM 267 CA GLN 138 0.269 5.478-4.570 1.00 0.00 ATOM 268 HA GLN 138 0.680 6.434-4.860 1.00 0.00 ATOM 269 CB GLN 138 0.419 4.500-5.743 1.00 0.00 ATOM 270 1HB GLN 138 0.006 4.958-6.630 1.00 0.00 ATOM 271 2HB GLN 138-0.140 3.603-5.520 1.00 0.00 ATOM 272 QB GLN 138-0.067 4.281-6.075 1.00 0.00 ATOM 273 CG GLN 138 1.861 4.103-6.039 1.00 0.00 ATOM 274 1HG GLN 138 1.862 3.144-6.536 1.00 0.00 ATOM 275 2HG GLN 138 2.397 4.023-5.105 1.00 0.00 ATOM 276 QG GLN 138 2.130 3.584-5.820 1.00 0.00 ATOM 277 CD GLN 138 2.576 5. 109-6.924 1.00 0.00 ATOM 278 OE1 GLN 138 2.042 5.537-7.944 1.00 0.00 ATOM 279 NE2 GLN 138 3.788 5.493-6.539 1.00 0. 00 ATOM 280 1HE2 GLN 138 4.159 5.1I5-5.713 1.00 0. 00 ATOM 281 2HE2 GLN 138 4.264 6.143-7.096 1.00 0.00 ATOM 282 QE2 GLN 138 4.212 5.629-6.404 1.00 0.00 ATOM 283 C GLN 138-1.202 5.661-4.231 1.00 0.00 ATOM 284 O GLN 138-1.730 5.004-3.333 1.00 0.00 ATOM 285 N GLU 139-1.862 6.546-4.966 1.00 0.00 ATOM 286 H GLU 139-1.390 7.026-5.676 1.00 0.00 ATOM 287 CA GLU 139-3.275 6.806-4.759 1.00 0.00 ATOM 288 HA GLU 139-3.566 6.312-3.843 1.00 0.00 ATOM 289 CB GLU 139-3.529 8.322-4.616 1.00 0.00 ATOM 290 1HB GLU 139-2.598 8.844-4.781 1.00 0.00 ATOM 291 2HB GLU 139-3. 862 8.519-3.609 1.00 0.00 ATOM 292 QB GLU 139-3.230 8.682-4.195 1.00 0.00 ATOM 293 CG GLU 139-4.571 8.900-5.569 1.00 0.00 ATOM 294 1HG GLU 139-4.656 8.250-6.427 1.00 0.00 ATOM 295 2HG GLU 139-4.243 9.877-5.890 1.00 0.00 ATOM 296 QG GLU 139-4.449 9.064-6.158 1.00 0.00 ATOM 297 CD GLU 139-5.935 9.037-4.928 1.00 0.00 ATOM 298 OE1 GLU 139-6.481 10.159-4.922 1.00 0.00 ATOM 299 OE2 GLU 139-6.460 8.024-4.428 1.00 0.00 ATOM 300 C GLU 139-4.075 6.202-5.910 1.00 0.00 ATOM 301 O GLU 139-3.713 6.347-7.079 1. 00 0.00 ATOM 302 N ARG+ 140-5.152 5.519-5.570 1.00 0.00 ATOM 303 H ARG+ 140-5.386 5.437-4.621 1.00 0.00 ATOM 304 CA ARG+ 140-6.007 4.892-6.560 1.00 0. 00 ATOM 305 HA ARG+ 140-5.633 5.154-7.539 1.00 0. 00 ATOM 306 CB ARG+ 140-5.995 3.363-6.403 1.00 0.00 ATOM 307 1HB ARG+ 140-6.513 3.106-5.487 1.00 0.00 ATOM 308 2HB ARG+ 140-4.972 3.027-6.335 1.00 0.00 ATOM 309 QB ARG+ 140-5.742 3.067-5.911 1.00 0.00 ATOM 310 CG ARG+ 140-6.669 2.619-7.547 1.00 0.00 ATOM 311 1HG ARG+ 140-7.676 2.998-7.661 1.00 0.00 ATOM 312 2HG ARG+ 140-6.704 1.568-7.307 1.00 0.00 ATOM 313 QG ARG+ 140-7.190 2.283-7.484 1.00 0.00 ATOM 314 CD ARG+ 140-5.923 2.803-8.857 1.00 0.00 ATOM 315 1HD ARG+ 140-4.913 3.121-8.642 1.00 0.00 ATOM 316 2HD ARG+ 140-6.425 3.569-9.435 1.00 0.00 ATOM 317 QD ARG+ 140-5.669 3.345-9.038 1.00 0.00 ATOM 318 NE ARG+ 140-5.879 1.567-9.640 1.00 0.00 ATOM 319 HE ARG+ 140-5.463 0.783-9.221 1.00 0.00 ATOM 320 CZ ARG+ 140-6.358 1.460-10.881 1.00 0.00 ATOM 321 NH1 ARG+ 140-6.970 2.491-11.450 1.00 0.00 ATOM 322 1HH1 ARG+ 140-7.081 3.361-10.943 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.335 2.416-12.377 1.00 0.00 ATOM 324 QH1 ARG+ 140-7.208 2.889-11.660 1.00 0.00 ATOM 325 NH2 ARG+ 140-6.245 0.312-11.541 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.800-0.474-11.110 1.00 0. 00 ATOM 327 2HH2 ARG+ 140-6. 606 0.230-12.471 1.00 0. 00 ATOM 328 QH2 ARG+ 140-6. 203-0.122-11.790 1.00 0. 00 ATOM 329 C ARG+ 140-7.426 5.420-6.415 1.00 0.00 ATOM 330 O ARG+ 140-8.267 4.787-5.774 1.00 0.00 ATOM 331 N MET 141-7.692 6.578-7.013 1.00 0.00 ATOM 332 H MET 141-6.981 7.031-7.511 1.00 0.00 ATOM 333 CA MET 141-9.019 7.187-6.954 1.00 0.00 ATOM 334 HA MET 141-9.380 7.092-5.942 1.00 0.00 ATOM 335 CB MET 141-8.941 8.674-7.326 1.00 0.00 ATOM 336 1HB MET 141-8.811 8.757-8.395 1.00 0.00

ATOM 337 2HB MET 141-8. 084 9.113-6.834 1.00 0.00 ATOM 338 QB MET 141-8. 447 8.935-7.614 1.00 0.00 ATOM 339 CG MET 141-10.177 9.473-6.934 1.00 0.00 ATOM 340 1HG MET 141-10.570 9.072-6.012 1.00 0.00 ATOM 341 2HG MET 141-10.916 9.368-7.714 1.00 0.00 ATOM 342 QG MET 141-10.743 9.220-6.863 1.00 0.00 ATOM 343 SD MET 141-9. 830 11.227-6.701 1.00 0.00 ATOM 344 QE MET 141-9.437 11.835-8.726 1.00 0.00 ATOM 345 CE MET 141-9.503 11.733-8.388 1.00 0.00 ATOM 346 1HE MET 141-8.980 10.943-8.905 1.00 0.00 ATOM 347 2HE MET 141-8.894 12.625-8.384 1.00 0.00 ATOM 348 3HE MET 141-10.437 11.937-8.891 1.00 0.00 ATOM 349 C MET 141-9.979 6.454-7.890 1.00 0.00 ATOM 350 O MET 141-10. 699 7.067-8.680 1.00 0.00 ATOM 351 N ASP 142-9.966 5.136-7.789 1.00 0.00 ATOM 352 H ASP 142-9.362 4.721-7.139 1.00 0.00 ATOM 353 CA ASP 142-10.797 4.281-8.605 1.00 0.00 ATOM 354 HA ASP 142-11.481 4.896-9.170 1.00 0.00 ATOM 355 CB ASP 142-9.925 3.472-9.564 1.00 0.00 ATOM 356 1HB ASP 142-10.557 2.814-10.127 1.00 0.00 ATOM 357 2HB ASP 142-9.227 2.884-8.991 1.00 0.00 ATOM 358 QB ASP 142-9.892 2.849-9.559 1.00 0. 00 ATOM 359 CG ASP 142-9. 139 4.329-10.531 1.00 0.00 ATOM 360 OD1 ASP 142-7.978 4. 667-10.212 1.00 0.00 ATOM 361 OD2 ASP 142-9.659 4.626-11.619 1.00 0.00 ATOM 362 C ASP 142-11.575 3.315-7.732 1.00 0.00 ATOM 363 O ASP 142-12.793 3.184-7.844 1.00 0.00 ATOM 364 N VAL 143-10.845 2.617-6.873 1.00 0.00 ATOM 365 H VAL 143-9.877 2.759-6.846 1.00 0.00 ATOM 366 CA VAL 143-11.440 1.632-5.991 1.00 0.00 ATOM 367 HA VAL 143-12.414 1.381-6.387 1.00 0.00 ATOM 368 CB VAL 143-10.586 0.347-5.953 1.00 0.00 ATOM 369 HB VAL 143-9.911 0.416-5.111 1.00 0.00 ATOM 370 QG1 VAL 143-11.666-1.168-5.710 1.00 0.00 ATOM 371 QG2 VAL 143-9.556 0.173-7.517 1.00 0.00 ATOM 372 CG1 VAL 143-11.461-0.878-5.756 1.00 0.00 ATOM 373 1HG1 VAL 143-12.327-0.808-6.396 1.00 0.00 ATOM 374 2HG1 VAL 143-11.776-0.934-4.725 1.00 0.00 ATOM 375 3HG1 VAL 143-10.896-1.763-6.009 1.00 0.00 ATOM 376 CG2 VAL 143-9.752 0.205-7.219 1.00 0.00 ATOM 377 1HG2 VAL 143-8.715 0.397-6.989 1.00 0.00 ATOM 378 2HG2 VAL 143-10.096 0.917-7.956 1.00 0.00 ATOM 379 3HG2 VAL 143-9.857-0.796-7.607 1.00 0.00 ATOM 380 QQG VAL 143-10.611-0.498-6.613 1.00 0.00 ATOM 381 C VAL 143-11.610 2.193-4.577 1.00 0. 00 ATOM 382 O VAL 143-10. 860 3.067-4.152 1.00 0.00 ATOM 383 N CYS 144-12.607 1.687-3.859 1.00 0.00 ATOM 384 H CYS 144-13.172 0.992-4.255 1.00 0.00 ATOM 385 CA CYS 144-12.890 2.137-2.497 1.00 0.00 ATOM 386 HA CYS 144-12. 013 2.644-2.113 1.00 0.00 ATOM 387 CB CYS 144-14.071 3.105-2.503 1.00 0.00 ATOM 388 1HB CYS 144-14.546 3.084-1.533 1.00 0.00 ATOM 389 2HB CYS 144-14.782 2.787-3.251 1.00 0.00 ATOM 390 QB CYS 144-14.664 2.936-2.392 1.00 0.00 ATOM 391 SG CYS 144-13.625 4.830-2.866 1.00 0.00 ATOM 392 C CYS 144-13.215 0.955-1.602 1.00 0.00 ATOM 393 O CYS 144-14.358 0.494-1.569 1.00 0.00 ATOM 394 N GLU 145-12.218 0.456-0.889 1.00 0.00 ATOM 395 H GLU 145-11.324 0.853-0.960 1.00 0.00 ATOM 396 CA GLU 145-12.415-0.686-0.018 1.00 0.00 ATOM 397 HA GLU 145-13.468-0.912-0.004 1.00 0.00 ATOM 398 CB GLU 145-11.674-1.887-0.586 1.00 0.00 ATOM 399 1HB GLU 145-11.422-2.556 0.221 1.00 0.00 ATOM 400 2HB GLU 145-10.761-1.545-1.056 1.00 0.00 ATOM 401 QB GLU 145-11. 091-2. 050-0.417 1.00 0.00 ATOM 402 CG GLU 145-12.491-2.658-1. 610 1.00 0.00 ATOM 403 1HG GLU 145-12. 034-3. 624-1.767 1.00 0.00 ATOM 404 2HG GLU 145-12.497-2.107-2.539 1.00 0.00 ATOM 405 QG GLU 145-12.265-2.865-2.153 1.00 0.00 ATOM 406 CD GLU 145-13.921-2.864-1.160 1.00 0.00 ATOM 407 OE1 GLU 145-14. 131-3.165 0.036 1.00 0.00 ATOM 408 OE2 GLU 145-14.836-2.692-1.985 1.00 0.00

ATOM 409 C GLU 145-11.956-0.412 1.406 1.00 0.00 ATOM 410 O GLU 145-11.480 0.680 1.722 1.00 0.00 ATOM 411 N THR 146-12.117-1.418 2.256 1.00 0.00 ATOM 412 H THR 146-12.511-2.255 1.929 1.00 0.00 ATOM 413 CA THR 146-11.740-1.325 3.657 1.00 0.00 ATOM 414 HA THR 146-12.046-0.355 4.022 1.00 0.00 ATOM 415 CB THR 146-12.469-2.412 4.449 1.00 0.00 ATOM 416 HB THR 146-11.854-3.301 4.466 1.00 0.00 ATOM 417 QG2 THR 146-12.839-1.935 6.224 1.00 0.00 ATOM 418 OG1 THR 146-13. 700-2.737 3.826 1.00 0.00 ATOM 419 1HG THR 146-14.428-2.411 4.366 1.00 0.00 ATOM 420 CG2 THR 146-12.768-2.028 5.881 1.00 0.00 ATOM 421 1HG2 THR 146-11.892-2.194 6.491 1.00 0.00 ATOM 422 2HG2 THR 146-13.584-2.629 6.255 1.00 0.00 ATOM 423 3HG2 THR 146-13.042-0.982 5.926 1.00 0.00 ATOM 424 C THR 146-10.227-1.467 3.825 1.00 0.00 ATOM 425 O THR 146-9.512-1.801 2.877 1.00 0.00 ATOM 426 N HIS+ 147-9.751-1.215 5.042 1.00 0.00 ATOM 427 H HIS+ 147-10.380-0.956 5.751 1.00 0.00 ATOM 428 CA HIS+ 147-8.327-1.309 5.360 1.00 0.00 ATOM 429 HA HIS+ 147-7.804-0.589 4.748 1.00 0.00 ATOM 430 CB HIS+ 147-8.097-0.965 6.834 1.00 0.00 ATOM 431 1HB HIS+ 147-7.963-1.882 7.391 1.00 0.00 ATOM 432 2HB HIS+ 147-8.963-0.444 7.214 1.00 0.00 ATOM 433 QB HIS+ 147-8.463-1.163 7.303 1.00 0.00 ATOM 434 CG HIS+ 147-6.899-0.100 7.074 1.00 0.00 ATOM 435 ND1 HIS+ 147-6.961 1.277 7.105 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.604-0.423 7.309 1.00 0.00 ATOM 437 1HD HIS+ 147-7.770 1.821 6.959 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.757 1.765 7.351 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.916 0.754 7.481 1.00 0.00 ATOM 440 2HD HIS+ 147-5.185-1.422 7.333 1.00 0.00 ATOM 441 1HE HIS+ 147-5.504 2.812 7.436 1.00 0.00 ATOM 442 2HE HIS+ 147-3.985 0.829 7.785 1.00 0.00 ATOM 443 C HIS+ 147-7.771-2.700 5.065 1.00 0.00 ATOM 444 O HIS+ 147-6.615-2.841 4.680 1.00 0.00 ATOM 445 N LEU 148-8.594-3.722 5.256 1.00 0.00 ATOM 446 H LEU 148-9.505-3.550 5.569 1.00 0.00 ATOM 447 CA LEU 148-8.173-5.098 5.017 1.00 0.00 ATOM 448 HA LEU 148-7.237-5.251 5.533 1.00 0.00 ATOM 449 CB LEU 148-9.215-6.069 5.581 1.00 0.00 ATOM 450 1HB LEU 148-10.192-5.742 5.261 1.00 0.00 ATOM 451 2HB LEU 148-9. 173-6.021 6.660 1.00 0.00 ATOM 452 QB LEU 148-9.682-5.881 5.961 1.00 0.00 ATOM 453 CG LEU 148-9.041-7.529 5.160 1.00 0.00 ATOM 454 HG LEU 148-8.645-7.561 4.155 1.00 0.00 ATOM 455 QD1 LEU 148-7.821-8.407 6.290 1.00 0.00 ATOM 456 QD2 LEU 148-10.697-8.419 5.163 1.00 0.00 ATOM 457 CD1 LEU 148-8.055-8.238 6.074 1.00 0.00 ATOM 458 1HD1 LEU 148-7.749-7.569 6.864 1.00 0.00 ATOM 459 2HD1 LEU 148-7.189-8.542 5.503 1.00 0.00 ATOM 460 3HD1 LEU 148-8.526-9.110 6.503 1.00 0.00 ATOM 461 CD2 LEU 148-10.380-8.248 5.162 1.00 0.00 ATOM 462 1HD2 LEU 148-10.985-7.881 5.978 1.00 0.00 ATOM 463 2HD2 LEU 148-10.217-9.309 5.284 1.00 0.00 ATOM 464 3HD2 LEU 148-10.888-8.067 4.227 1.00 0.00 ATOM 465 QQD LEU 148-9.259-8.413 5.727 1.00 0.00 ATOM 466 C LEU 148-7.960-5.365 3.530 1.00 0.00 ATOM 467 O LEU 148-7.012-6.047 3.150 1.00 0.00 ATOM 468 N HIS+ 149-8.846-4.835 2.694 1.00 0.00 ATOM 469 H HIS+ 149-9.586-4.303 3.054 1.00 0.00 ATOM 470 CA HIS+ 149-8.746-5.038 1.252 1.00 0.00 ATOM 471 HA HIS+ 149-8.755-6.105 1.079 1.00 0.00 ATOM 472 CB HIS+ 149-9.941-4.425 0.532 1.00 0.00 ATOM 473 1HB HIS+ 149-9.590-3.712-0.201 1.00 0.00 ATOM 474 2HB HIS+ 149-10.568-3.913 1.248 1.00 0.00 ATOM 475 QB HIS+ 149-10.079-3.812 0.524 1.00 0.00 ATOM 476 CG HIS+ 149-10.779-5.442-0.177 1.00 0.00 ATOM 477 ND1 HIS+ 149-10.261-6.348-1.078 1.00 0.00 ATOM 478 CD2 HIS+ 149-12.107-5.691-0.115 1.00 0.00 ATOM 479 1HD HIS+ 149-9.317-6.421-1.343 1.00 0.00 ATOM 480 CE1 HIS+ 149-11.238-7.110-1.541 1.00 0.00

ATOM 481 NE2 HIS+ 149-12. 371-6. 731-0.972 1.00 0.00 ATOM 482 2HD HIS+ 149-12.832-5.159 0.488 1.00 0.00 ATOM 483 1HE HIS+ 149-11. 128-7.908-2.261 1.00 0.00 ATOM 484 2HE HIS+ 149-13. 265-6. 984-1.287 1.00 0.00 ATOM 485 C HIS+ 149-7.446-4.479 0.695 1.00 0.00 ATOM 486 O HIS+ 149-6.699-5.200 0.042 1.00 0.00 ATOM 487 N TRP 150-7. 170-3.204 0.956 1.00 0.00 ATOM 488 H TRP 150-7. 804-2. 672 1.485 1.00 0.00 ATOM 489 CA TRP 150-5.935-2.582 0.470 1.00 0.00 ATOM 490 HA TRP 150-5. 890-2. 717-0.602 1.00 0.00 ATOM 491 CB TRP 150-5.896-1.092 0.798 1.00 0.00 ATOM 492 1HB TRP 150-4. 933-0.696 0.504 1.00 0.00 ATOM 493 2HB TRP 150-6. 014-0.965 1.863 1.00 0.00 ATOM 494 QB TRP 150-5. 473-0.830 1.184 1.00 0.00 ATOM 495 CG TRP 150-6.953-0.275 0.122 1.00 0.00 ATOM 496 CD1 TRP 150-7. 370 0.969 0.490 1.00 0.00 ATOM 497 CD2 TRP 150-7. 722-0.629-1.034 1.00 0.00 ATOM 498 CE3 TRP 150-7.768-1.749-1.868 1.00 0.00 ATOM 499 CE2 TRP 150-8. 583 0.450-1.302 1.00 0.00 ATOM 500 NE1 TRP 150-8.350 1.409-0.358 1.00 0.00 ATOM 501 HD TRP 150-6.977 1.516 1.334 1.00 0.00 ATOM 502 3HE TRP 150-7.124-2.599-1.697 1.00 0.00 ATOM 503 CZ3 TRP 150-8. 655-1.757-2.920 1.00 0.00 ATOM 504 CZ2 TRP 150-9. 474 0.440-2.363 1.00 0.00 ATOM 505 1HE TRP 150-8. 809 2.276-0.298 1.00 0.00 ATOM 506 3HZ TRP 150-8. 708-2.615-3.574 1.00 0.00 ATOM 507 CH2 TRP 150-9. 496-0. 669-3.158 1.00 0.00 ATOM 508 2HZ TRP 150-10. 134 1.273-2.565 1.00 0.00 ATOM 509 HH TRP 150-10. 177-0. 718-3.995 1.00 0.00 ATOM 510 C TRP 150-4. 728-3.261 1.075 1.00 0.00 ATOM 511 O TRP 150-3.700-3.383 0.426 1.00 0.00 ATOM 512 N HIS+ 151-4.868-3.725 2.309 1.00 0.00 ATOM 513 H HIS+ 151-5.726-3.612 2.769 1.00 0.00 ATOM 514 CA HIS+ 151-3. 786-4. 425 2.979 1.00 0.00 ATOM 515 HA HIS+ 151-2.929-3.770 3.013 1.00 0.00 ATOM 516 CB HIS+ 151-4.208-4.802 4.410 1.00 0.00 ATOM 517 1HB HIS+ 151-5.104-5.406 4.357 1.00 0.00 ATOM 518 2HB HIS+ 151-4.428-3.899 4.957 1.00 0.00 ATOM 519 QB HIS+ 151-4.766-4.652 4.657 1.00 0.00 ATOM 520 CG HIS+ 151-3. 182-5. 572 5.196 1.00 0.00 ATOM 521 ND1 HIS+ 151-2. 772-5. 204 6.459 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.502-6.709 4.903 1.00 0.00 ATOM 523 1HD HIS+ 151-3.082-4.418 6.957 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.887-6.078 6.905 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.707-7.002 5.983 1.00 0.00 ATOM 526 2HD HIS+ 151-2. 563-7. 269 3.978 1.00 0.00 ATOM 527 1HE HIS+ 151-1.384-6.036 7.861 1.00 0.00 ATOM 528 2HE HIS+ 151-1.244-7.853 6.129 1. 00 0.00 ATOM 529 C HIS+ 151-3.435-5.672 2.180 1.00 0.00 ATOM 530 0 HIS+ 151-2.263-5.964 1.946 1.00 0.00 ATOM 531 N THR 152-4.466-6.394 1.759 1.00 0.00 ATOM 532 H THR 152-5. 375-6. 099 1.975 1.00 0.00 ATOM 533 CA THR 152-4. 282-7.604 0.980 1.00 0.00 ATOM 534 HA THR 152-3.547-8.211 1.488 1.00 0.00 ATOM 535 CB THR 152-5. 595-8. 389 0.886 1.00 0.00 ATOM 536 HB THR 152-6.240-7.909 0.164 1.00 0.00 ATOM 537 QG2 THR 152-5. 364-10. 171 0.356 1.00 0.00 ATOM 538 OG1 THR 152-6. 256-8. 406 2.141 1.00 0.00 ATOM 539 1HG THR 152-6. 531-7. 512 2.376 1.00 0.00 ATOM 540 CG2 THR 152-5. 409-9. 828 0.459 1.00 0.00 ATOM 541 1HG2 THR 152-6. 313-10. 383 0.659 1.00 0.00 ATOM 542 2HG2 THR 152-4. 589-10. 265 1.009 1.00 0.00 ATOM 543 3HG2 THR 152-5. 191-9. 865-0.601 1.00 0.00 ATOM 544 C THR 152-3.746-7.279-0.406 1.00 0.00 ATOM 545 O THR 152-2.758-7.860-0.814 1.00 0.00 ATOM 546 N VAL 153-4. 378-6. 336-1. 112 1.00 0.00 ATOM 547 H VAL 153-5. 158-5. 884-0.722 1.00 0.00 ATOM 548 CA VAL 153-3. 917-5. 950-2.450 1.00 0.00 ATOM 549 HA VAL 153-3.992-6.817-3.088 1.00 0.00 ATOM 550 CB VAL 153-4. 782-4. 817-3.050 1.00 0.00 ATOM 551 HB VAL 153-4.660-3.935-2.438 1.00 0.00 ATOM 552 QG1 VAL 153-4. 227-4. 402-4.799 1.00 0.00

ATOM 553 QG2 VAL 153-6.599-5.299-3.040 1.00 0.00 ATOM 554 CG1 VAL 153-4.334-4.481-4.465 1.00 0.00 ATOM 555 1HG1 VAL 153-3.330-4.849-4.621 1.00 0.00 ATOM 556 2HG1 VAL 153-4.351-3.410-4.604 1.00 0.00 ATOM 557 3HG1 VAL 153-5.001-4.948-5.174 1.00 0.00 ATOM 558 CG2 VAL 153-6.252-5.206-3.042 1.00 0.00 ATOM 559 1HG2 VAL 153-6.643-5.115-2.039 1.00 0.00 ATOM 560 2HG2 VAL 153-6.354-6.229-3.377 1.00 0.00 ATOM 561 3HG2 VAL 153-6.800-4.554-3.705 1.00 0.00 ATOM 562 QQG VAL 153-5.413-4.851-3.920 1.00 0.00 ATOM 563 C VAL 153-2.460-5.513-2.399 1.00 0.00 ATOM 564 O VAL 153-1.641-5.916-3.228 1.00 0.00 ATOM 565 N ALA 154-2.145-4.704-1.401 1.00 0.00 ATOM 566 H ALA 154-2.850-4.433-0.766 1.00 0.00 ATOM 567 CA ALA 154-0.788-4.223-1.202 1.00 0.00 ATOM 568 HA ALA 154-0.474-3.696-2.091 1.00 0.00 ATOM 569 QB ALA 154-0.747-3.033 0.249 1.00 0.00 ATOM 570 CB ALA 154-0. 755-3.262-0.030 1.00 0.00 ATOM 571 1HB ALA 154-0.134-2.413-0.278 1.00 0.00 ATOM 572 2HB ALA 154-0. 350-3.764 0.836 1.00 0.00 ATOM 573 3HB ALA 154-1.758-2.922 0.187 1.00 0.00 ATOM 574 C ALA 154 0.159-5.386-0.948 1.00 0.00 ATOM 575 O ALA 154 1.183-5.532-1.620 1.00 0.00 ATOM 576 N LYS+ 155-0.196-6.216 0.028 1.00 0.00 ATOM 577 H LYS+ 155-1.030-6.044 0.521 1.00 0.00 ATOM 578 CA LYS+ 155 0.610-7.376 0.379 1.00. 0.00 ATOM 579 HA LYS+ 155 1.598-7.027 0.658 1.00 0.00 ATOM 580 CB LYS+ 155-0.016-8.132 1.560 1.00 0.00 ATOM 581 1HB LYS+ 155-1.022-8.424 1.285 1.00 0.00 ATOM 582 2HB LYS+ 155-0.068-7.470 2.410 1.00 0.00 ATOM 583 QB LYS+ 155-0.545-7.947 1.848 1.00 0.00 ATOM 584 CG LYS+ 155 0.746-9.388 1.971 1.00 0.00 ATOM 585 1HG LYS+ 155 1.546-9.558 1.265 1.00 0.00 ATOM 586 2HG LYS+ 155 0. 065-10. 227 1.953 1.00 0.00 ATOM 587 QG LYS+ 155 0.806-9.892 1.609 1.00 0.00 ATOM 588 CD LYS+ 155 1.337-9.264 3.370 1.00 0.00 ATOM 589 1HD LYS+ 155 0.540-9.363 4.093 1.00 0.00 ATOM 590 2HD LYS+ 155 1.795-8.290 3.472 1.00 0.00 ATOM 591 QD LYS+ 155 1.168-8.826 3.783 1.00 0.00 ATOM 592 CE LYS+ 155 2.390-10.336 3.642 1.00 0.00 ATOM 593 1HE LYS+ 155 2.253-10.707 4.649 1.00 0.00 ATOM 594 2HE LYS+ 155 3.370-9.887 3.559 1.00 0.00 ATOM 595 QE LYS+ 155 2.812-10.297 4.104 1.00 0.00 ATOM 596 NZ LYS+ 155 2.301-11.480 2.686 1.00 0.00 ATOM 597 1HZ LYS+ 155 2.640-11.189 1.735 1.00 0.00 ATOM 598 2HZ LYS+ 155 1.318-11. 805 2.603 1.00 0.00 ATOM 599 3HZ LYS+ 155 2.887-12.273 3.019 1.00 0.00 ATOM 600 QZ LYS+ 155 2.282-11.756 2.453 1.00 0.00 ATOM 601 C LYS+ 155 0.743-8.300-0.820 1.00 0.00 ATOM 602 O LYS+ 155 1.839-8.750-1.117 1.00 0.00 ATOM 603 N GLU 156-0.372-8.566-1.496 1.00 0.00 ATOM 604 H GLU 156-1.221-8. 164-1.196 1.00 0.00 ATOM 605 CA GLU 156-0.386-9.430-2.671 1.00 0.00 ATOM 606 HA GLU 156-0.141-10.432-2.351 1.00 0.00 ATOM 607 CB GLU 156-1.773-9.441-3.318 1.00 0.00 ATOM 608 1HB GLU 156-1. 669-9. 712-4.358 1.00 0.00 ATOM 609 2HB GLU 156-2.195-8.448-3.257 1.00 0.00 ATOM 610 QB GLU 156-1.932-9.080-3.807 1.00 0.00 ATOM 611 CG GLU 156-2.748-10.409-2.670 1.00 0.00 ATOM 612 1HG GLU 156-2.611-10.377-1.600 1.00 0.00 ATOM 613 2HG GLU 156-2.542-11.403-3.032 1.00 0.00 ATOM 614 QG GLU 156-2.576-10.890-2.316 1.00 0.00 ATOM 615 CD GLU 156-4.191-10.072-2.983 1.00 0.00 ATOM 616 OE1 GLU 156-5.062-10. 939-2.770 1.00 0.00 ATOM 617 OE2 GLU 156-4.450-8.938-3.437 1.00 0.00 ATOM 618 C GLU 156 0.645-8.975-3.689 1.00 0.00 ATOM 619 O GLU 156 1.498-9.752-4.083 1.00 0.00 ATOM 620 N THR 157 0.563-7.713-4.101 1.00 0.00 ATOM 621 H THR 157-0.151-7.141-3.739 1.00 0.00 ATOM 622 CA THR 157 1.500-7.155-5.077 1.00 0.00 ATOM 623 HA THR 157 1.314-7.642-6.023 1.00 0.00 ATOM 624 CB THR 157 1.252-5.649-5.239 1.00 0.00

ATOM 625 HB THR 157 1.581-5.142-4.342 1.00 0.00 ATOM 626 QG2 THR 157 2.159-4.893-6.692 1.00 0.00 ATOM 627 OG1 THR 157-0.129-5.383-5.421 1.00 0.00 ATOM 628 1HG THR 157-0.621-5.644-4.628 1.00 0.00 ATOM 629 CG2 THR 157 1.985-5.038-6.413 1.00 0.00 ATOM 630 1HG2 THR 157 1.285-4.495-7.031 1.00 0.00 ATOM 631 2HG2 THR 157 2.447-5.821-6.996 1.00 0.00 ATOM 632 3HG2 THR 157 2.745-4.362-6.051 1.00 0.00 ATOM 633 C THR 157 2.961-7.411-4.678 1.00 0.00 ATOM 634 O THR 157 3.791-7.773-5.513 1.00 0.00 ATOM 635 N CYS 158 3.275-7.215-3.404 1.00 0.00 ATOM 636 H CYS 158 2.576-6.914-2.778 1.00 0.00 ATOM 637 CA CYS 158 4.635-7.420-2.914 1.00 0.00 ATOM 638 HA CYS 158 5.313-7.009-3.647 1.00 0.00 ATOM 639 CB CYS 158 4.822-6.659-1.604 1.00 0.00 ATOM 640 1HB CYS 158 5.719-6.997-1.120 1.00 0.00 ATOM 641 2HB CYS 158 3.980-6.860-0.962 1.00 0.00 ATOM 642 QB CYS 158 4.850-6.928-1.041 1.00 0.00 ATOM 643 SG CYS 158 4.941-4.847-1.821 1.00 0.00 ATOM 644 C CYS 158 4.969-8.909-2.741 1.00 0.00 ATOM 645 O CYS 158 6.021-9.363-3.192 1.00 0.00 ATOM 646 N SER 159 4.081-9.661-2.087 1.00 0.00 ATOM 647 H SER 159 3.265-9.243-1.745 1.00 0.00 ATOM 648 CA SER 159 4.293-11.096-1.856 1.00 0.00 ATOM 649 HA SER 159 5.276-11.212-1.422 1.00 0.00 ATOM 650 CB SER 159 3.257-11.650-0.876 1.00 0.00 ATOM 651 1HB SER 159 3.635-12.563,-0.439 1.00 0.00 ATOM 652 2HB SER 159 2.340-11.859-1.408 1.00 0.00 ATOM 653 QB SER 159 2.988-12.211-0.923 1.00 0.00 ATOM 654 OG SER 159 2.983-10.720 0.164 1.00 0.00 ATOM 655 HG SER 159 2.568-9.934-0.223 1.00 0.00 ATOM 656 C SER 159 4.247-11.900-3.159 1.00 0.00 ATOM 657 O SER 159 4.789-13.000-3.223 1.00 0.00 ATOM 658 N GLU 160 3.613-11.343-4.192 1.00 0.00 ATOM 659 H GLU 160 3.202-10.458-4.083 1.00 0.00 ATOM 660 CA GLU 160 3.527-12.007-5.492 1.00 0.00 ATOM 661 HA GLU 160 3.157-13.010-5.338 1.00 0.00 ATOM 662 CB GLU 160 2.573-11.240-6.422 1.00 0.00 ATOM 663 1HB GLU 160 2.981-10.254-6.599 1.00 0.00 ATOM 664 2HB GLU 160 1.618-11.136-5.930 1.00 0.00 ATOM 665 QB GLU 160 2.300-10.695-6.264 1.00 0.00 ATOM 666 CG GLU 160 2.339-11.901-7.773 1.00 0.00 ATOM 667 1HG GLU 160 1.275-11.974-7.948 1.00 0.00 ATOM 668 2HG GLU 160 2.771-12.890-7.758 1.00 0.00 ATOM 669 QG GLU 160 2.023-12.432-7.853 1.00 0.00 ATOM 670 CD GLU 160 2.963-11.116-8.904 1.00 0.00 ATOM 671 OE1 GLU 160 3.435-11.740-9.877 1.00 0.00 ATOM 672 OE2 GLU 160 3.031-9.873-8.800 1.00 0.00 ATOM 673 C GLU 160 4.923-12.072-6.097 1.00 0.00 ATOM 674 O GLU 160 5.230-12.911-6.945 1.00 0.00 ATOM 675 N LYS+ 161 5.776-11.180-5.623 1.00 0.00 ATOM 676 H LYS+ 161 5.472-10.554-4.934 1.00 0.00 ATOM 677 CA LYS+ 161 7.148-11.119-6.061 1.00 0.00 ATOM 678 HA LYS+ 161 7.252-11.746-6.935 1.00 0.00 ATOM 679 CB LYS+ 161 7.531-9.676-6.410 1.00 0.00 ATOM 680 1HB LYS+ 161 7.958-9.212-5.532 1.00 0.00 ATOM 681 2HB LYS+ 161 6.640-9.137-6.689 1.00 0.00 ATOM 682 QB LYS+ 161 7.299-9.174-6.110 1.00 0.00 ATOM 683 CG LYS+ 161 8.541-9.561-7.547 1.00 0.00 ATOM 684 1HG LYS+ 161 9.523-9.808-7.167 1.00 0.00 ATOM 685 2HG LYS+ 161 8.542-8.544-7.911 1.00 0.00 ATOM 686 QG LYS+ 161 9.033-9.176-7.539 1.00 0.00 ATOM 687 CD LYS+ 161 8.209-10.499-8.705 1.00 0.00 ATOM 688 1HD LYS+ 161 7.990-11.480-8.308 1.00 0.00 ATOM 689 2HD LYS+ 161 9.067-10.561-9.359 1.00 0.00 ATOM 690 QD LYS+ 161 8.529-11.020-8.833 1.00 0.00 ATOM 691 CE LYS+ 161 7.011-10.011-9.513 1.00 0.00 ATOM 692 1HE LYS+ 161 7.104-10.375-10.526 1.00 0.00 ATOM 693 2HE LYS+ 161 7.013-8.931-9.519 1.00 0.00 ATOM 694 QE LYS+ 161 7.059-9.653-10.022 1.00 0.00 ATOM 695 NZ LYS+ 161 5.723-10.488-8.944 1.00 0.00 ATOM 696 1HZ LYS+ 161 5.876-10.966-8.034 1.00 0.00

ATOM 697 2HZ LYS+ 161 5.257-11. 164-9.595 1.00 0.00 ATOM 698 3HZ LYS+ 161 5.066-9.690-8.793 1.00 0.00 ATOM 699 QZ LYS+ 161 5.400-10.607-8.807 1.00 0.00 ATOM 700 C LYS+ 161 8. 030-11.665-4.946 1.00 0.00 ATOM 701 O LYS+ 161 7.688-12.659-4.313 1.00 0.00 ATOM 702 N SER 162 9.150-11. 021-4.697 1.00 0.00 ATOM 703 H SER 162 9.381-10.233-5.222 1.00 0.00 ATOM 704 CA SER 162 10.045-11.465-3. 650 1.00 0.00 ATOM 705 HA SER 162 9.656-12.391-3.257 1.00 0.00 ATOM 706 CB SER 162 11.440-11.719-4.222 1.00 0.00 ATOM 707 1HB SER 162 11.771-12.705-3.930 1.00 0. 00 ATOM 708 2HB SER 162 12.125-10. 981-3.829 1.00 0. 00 ATOM 709 QB SER 162 11.948-11.843-3.879 1.00 0.00 ATOM 710 OG SER 162 11.435-11.634-5.643 1.00 0.00 ATOM 711 HG SER 162 12.021-12.305-6.002 1.00 0.00 ATOM 712 C SER 162 10.122-10.445-2.518 1.00 0.00 ATOM 713 O SER 162 11.210-10. 071-2.095 1.00 0.00 ATOM 714 N THR 163 8.974-9.981-2.024 1.00 0.00 ATOM 715 H THR 163 8.117-10.296-2.393 1.00 0.00 ATOM 716 CA THR 163 8.976-9.012-0. 933 1.00 0.00 ATOM 717 HA THR 163 9.902-9.141-0.387 1.00 0.00 ATOM 718 CB THR 163 8.914-7.573-1.450 1.00 0.00 ATOM 719 HB THR 163 8.884-6.912-0.591 1.00 0.00 ATOM 720 QG2 THR 163 10.378-7.069-2.506 1.00 0.00 ATOM 721 OG1 THR 163 7.746-7.365-2.218 1.00 0.00 ATOM 722 1HG THR 163 7.506-8.188-2.668 1.00 0.00 ATOM 723 CG2 THR 163 10.096-7.165-2.303 1.00 0.00 ATOM 724 1HG2 THR 163 10.719-8.029-2.491 1.00 0.00 ATOM 725 2HG2 THR 163 10.672-6.413-1.785 1.00 0.00 ATOM 726 3HG2 THR 163 9.743-6.765-3.242 1.00 0.00 ATOM 727 C THR 163 7.816-9.250 0.030 1.00 0. 00 ATOM 728 O THR 163 6.831-9.908-0.302 1.00 0.00 ATOM 729 N ASN 164 7.944-8.699 1.227 1.00 0.00 ATOM 730 H ASN 164 8.761-8.184 1.426 1.00 0.00 ATOM 731 CA ASN 164 6.917-8.834 2.261 1.00 0.00 ATOM 732 HA ASN 164 6.049-9.298 1.806 1.00 0.00 ATOM 733 CB ASN 164 7.425-9.717 3.410 1.00 0.00 ATOM 734 1HB ASN 164 7.150-10.743 3.216 1.00 0.00 ATOM 735 2HB ASN 164 6.968-9.395 4.334 1.00 0.00 ATOM 736 QB ASN 164 7.059-10.069 3.775 1.00 0.00 ATOM 737 CG ASN 164 8.933-9.648 3.574 1.00 0. 00 ATOM 738 OD1 ASN 164 9.587-10.661 3.786 1.00 0.00 ATOM 739 ND2 ASN 164 9.487-8.445 3.491 1.00 0.00 ATOM 740 1HD2 ASN 164 8.897-7.676 3.348 1.00 0.00 ATOM 741 2HD2 ASN 164 10.461-8.380 3.526 1.00 0.00 ATOM 742 QD2 ASN 164 9.679-8.028 3.437 1.00 0. 00 ATOM 743 C ASN 164 6.525-7.466 2.812 1.00 0.00 ATOM 744 O ASN 164 7.391-6.647 3.112 1.00 0.00 ATOM 745 N LEU 165 5.224-7.223 2.940 1.00 0.00 ATOM 746 H LEU 165 4.584-7.916 2.683 1.00 0.00 ATOM 747 CA LEU 165 4.723-5.946 3.455 1.00 0.00 ATOM 748 HA LEU 165 5.221-5.147 2.925 1.00 0.00 ATOM 749 CB LEU 165 3.214-5.827 3.229 1.00 0.00 ATOM 750 1HB LEU 165 2.734-5.691 4.186 1.00 0.00 ATOM 751 2HB LEU 165 2.858-6.748 2.792 1.00 0.00 ATOM 752 QB LEU 165 2.796-6.219 3.489 1.00 0.00 ATOM 753 CG LEU 165 2.785-4.680 2.336 1.00 0.00 ATOM 754 HG LEU 165 3.335-3.790 2.606 1.00 0.00 ATOM 755 QD1 LEU 165 3.161-5.081 0.548 1.00 0.00 ATOM 756 QD2 LEU 165 0.954-4.332 2.570 1.00 0.00 ATOM 757 CD1 LEU 165 3.090-5.005 0.893 1.00 0.00 ATOM 758 1HD1 LEU 165 3.876-4.356 0.536 1.00 0.00 ATOM 759 2HD1 LEU 165 2.201-4.854 0.295 1.00 0.00 ATOM 760 3HD1 LEU 165 3.407-6.033 0.813 1.00 0.00 ATOM 761 CD2 LEU 165 1.305-4.400 2.525 1.00 0.00 ATOM 762 1HD2 LEU 165 0.728-5.223 2.133 1.00 0.00 ATOM 763 2HD2 LEU 165 1.041-3.494 1.999 1.00 0.00 ATOM 764 3HD2 LEU 165 1.092-4.280 3.578 1.00 0.00 ATOM 765 QQD LEU 165 2.058-4.707 1.559 1.00 0.00 ATOM 766 C LEU 165 5.010-5.791 4.936 1.00 0.00 ATOM 767 0 LEU 165 4.630-6.638 5.742 1.00 0.00 ATOM 768 N HIS+ 166 5.668-4.697 5.278 1.00 0.00

ATOM 769 H HIS+ 166 5. 934-4.059 4.579 1.00 0.00 ATOM 770 CA HIS+ 166 6.001-4.400 6.658 1.00 0.00 ATOM 771 HA HIS+ 166 5.697-5.241 7.263 1.00 0.00 ATOM 772 CB HIS+ 166 7.515-4.200 6.798 1.00 0.00 ATOM 773 1HB HIS+ 166 7.819-3.382 6.159 1.00 0.00 ATOM 774 2HB HIS+ 166 8.020-5.100 6.482 1.00 0.00 ATOM 775 QB HIS+ 166 7.920-4.241 6.321 1.00 0.00 ATOM 776 CG HIS+ 166 7.968-3.886 8.190 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.933-4.795 9.226 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.459-2.743 8.711 1.00 0.00 ATOM 779 1HD HIS+ 166 7.620-5.722 9.165 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.384-4.217 10.327 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.710-2.967 10.039 1.00 0.00 ATOM 782 2HD HIS+ 166 8.606-1.809 8.178 1.00 0.00 ATOM 783 1HE HIS+ 166 8.471-4.685 11.297 1.00 0.00 ATOM 784 2HE HIS+ 166 8.861-2.262 10.703 1.00 0.00 ATOM 785 C HIS+ 166 5.245-3.154 7.128 1.00 0.00 ATOM 786 O HIS+ 166 4.621-3.165 8.189 1.00 0.00 ATOM 787 N ASP 167 5.305-2.085 6.332 1.00 0.00 ATOM 788 H ASP 167 5.819-2.137 5.497 1.00 0.00 ATOM 789 CA ASP 167 4.628-0.831 6. 684 1.00 0.00 ATOM 790 HA ASP 167 4.136-0.985 7.633 1.00 0.00 ATOM 791 CB ASP 167 5.632 0.322 6. 835 1.00 0.00 ATOM 792 1HB ASP 167 5.234 1.043 7.535 1.00 0.00 ATOM 793 2HB ASP 167 5.762 0.801 5.877 1.00 0.00 ATOM 794 QB ASP 167 5.498 0.922 6.706 1.00 0.00 ATOM 795 CG ASP 167 6.992-0.120 7.330 1.00 0.00 ATOM 796 OD1 ASP 167 7.804-0.596 6.504 1.00 0.00 ATOM 797 OD2 ASP 167 7.254 0.016 8.543 1.00 0.00 ATOM 798 C ASP 167 3.575-0.440 5.648 1.00 0.00 ATOM 799 O ASP 167 3.865 0.267 4.686 1.00 0.00 ATOM 800 N TYR 168 2.353-0.900 5.854 1.00 0.00 ATOM 801 H TYR 168 2.186-1.453 6.645 1.00 0.00 ATOM 802 CA TYR 168 1.236-0.595 4.954 1.00 0.00 ATOM 803 HA TYR 168 1.637-0.384 3.967 1.00 0.00 ATOM 804 CB TYR 168 0.297-1.801 4.872 1.00 0.00 ATOM 805 1HB TYR 168 0.604-2.435 4.054 1.00 0.00 ATOM 806 2HB TYR 168-0.711-1.453 4.695 1.00 0.00 ATOM 807 QB TYR 168-0.053-1.944 4.375 1.00 0.00 ATOM 808 QD TYR 168 0.290-2.726 6.285 1.00 0.00 ATOM 809 QE TYR 168 0.295-4.052 8.352 1.00 0.00 ATOM 810 QR TYR 168 0.292-3.389 7.318 1.00 0.00 ATOM 811 CG TYR 168 0.288-2.632 6.137 1.00 0.00 ATOM 812 CD1 TYR 168 1.116-3.740 6. 272 1.00 0.00 ATOM 813 1HD TYR 168 1.763-4.015 5.454 1.00 0.00 ATOM 814 CE1 TYR 168 1.122-4.488 7.432 1.00 0.00 ATOM 815 1HE TYR 168 1.774-5.345 7.518 1.00 0.00 ATOM 816 CZ TYR 168 0.296-4.134 8.476 1.00 0.00 ATOM 817 CE2 TYR 168-0.536-3.039 8.367 1.00 0.00 ATOM 818 2HE TYR 168-1.184-2.760 9.185 1.00 0.00 ATOM 819 CD2 TYR 168-0.535-2.296 7.204 1.00 0.00 ATOM 820 2HD TYR 168-1.184-1.437 7.116 1.00 0.00 ATOM 821 OH TYR 168 0.298-4.879 9.630 1.00 0.00 ATOM 822 HH TYR 168 1.103-4.703 10.125 1.00 0.00 ATOM 823 C TYR 168 0.462 0.628 5.442 1.00 0.00 ATOM 824 O TYR 168 0.327 0.850 6.645 1.00 0.00 ATOM 825 N GLY 169-0.063 1.402 4.507 1.00 0.00 ATOM 826 H GLY 169 0.062 1.169 3.561 1.00 0.00 ATOM 827 CA GLY 169-0.831 2.579 4.854 1.00 0.00 ATOM 828 1HA GLY 169-0.174 3.436 4.878 1.00 0.00 ATOM 829 2HA GLY 169-1.268 2.439 5.832 1.00 0.00 ATOM 830 QA GLY 169-0.721 2.938 5.355 1.00 0.00 ATOM 831 C GLY 169-1.925 2.824 3.846 1.00 0.00 ATOM 832 O GLY 169-1.799 2.424 2.697 1.00 0.00 ATOM 833 N MET 170-2.999 3.465 4.265 1.00 0.00 ATOM 834 H MET 170-3.048 3.759 5.197 1.00 0.00 ATOM 835 CA MET 170-4.116 3.749 3.368 1.00 0.00 ATOM 836 HA MET 170-3.836 3.435 2.361 1.00 0.00 ATOM 837 CB MET 170-5.373 2.991 3.820 1.00 0.00 ATOM 838 1HB MET 170-6.239 3.591 3.577 1.00 0.00 ATOM 839 2HB MET 170-5.332 2.865 4.891 1.00 0.00 ATOM 840 QB MET 170-5.785 3.228 4.234 1.00 0.00

ATOM 841 CG MET 170-5. 560 1.615 3.191 1.00 0.00 ATOM 842 1HG MET 170-5. 957 1.747 2.195 1.00 0.00 ATOM 843 2HG MET 170-6.271 1.060 3.784 1.00 0.00 ATOM 844 QG MET 170-6.114 1.404 2.990 1.00 0.00 ATOM 845 SD MET 170-4.041 0.653 3.078 1.00 0.00 ATOM 846 QE MET 170-4.452-0.960 4.434 1.00 0.00 ATOM 847 CE MET 170-4.382-0. 690 4.206 1.00 0.00 ATOM 848 1HE MET 170-4.943-0.316 5.050 1.00 0.00 ATOM 849 2HE MET 170-3.452-1.116 4.550 1.00 0.00 ATOM 850 3HE MET 170-4.960-1. 449 3.700 1.00 0.00 ATOM 851 C MET 170-4.398 5.245 3.362 1.00 0.00 ATOM 852 O MET 170-4.625 5.843 4.414 1.00 0.00 ATOM 853 N LEU 171-4.376 5.847 2.183 1.00 0.00 ATOM 854 H LEU 171-4. 186 5.321 1.378 1.00 0.00 ATOM 855 CA LEU 171-4. 618 7.277 2.060 1.00 0.00 ATOM 856 HA LEU 171-4.780 7.665 3.054 1.00 0. 00 ATOM 857 CB LEU 171-3.390 7.974 1.454 1.00 0.00 ATOM 858 1HB LEU 171-2.564 7.860 2.143 1.00 0.00 ATOM 859 2HB LEU 171-3.612 9.025 1.359 1.00 0.00 ATOM 860 QB LEU 171-3.088 8.443 1.751 1.00 0.00 ATOM 861 CG LEU 171-2.943 7.451 0.083 1.00 0.00 ATOM 862 HG LEU 171-3.762 6.923-0.380 1.00 0.00 ATOM 863 QD1 LEU 171-2.452 8.869-1.045 1.00 0.00 ATOM 864 QD2 LEU 171-1.506 6.256 0.266 1.00 0.00 ATOM 865 CD1 LEU 171-2.546 8. 597-0.828 1.00 0.00 ATOM 866 1HD1 LEU 171-1. 757 8.273-1.489 1.00 0.00 ATOM 867 2HD1 LEU 171-2.199 9.428-0.233 1.00 0.00 ATOM 868 3HD1 LEU 171-3.401 8.905-1.413 1.00 0.00 ATOM 869 CD2 LEU 171-1.782 6.486 0.230 1.00 0.00 ATOM 870 1HD2 LEU 171-1.292 6.652 1.180 1.00 0.00 ATOM 871 2HD2 LEU 171-1.076 6.646-0.571 1.00 0.00 ATOM 872 3HD2 LEU 171-2.149 5.471 0.188 1.00 0.00 ATOM 873 QQD LEU 171-1.979 7.563-0.389 1.00 0.00 ATOM 874 C LEU 171-5.855 7.566 1.217 1.00 0.00 ATOM 875 O LEU 171-6.583 6.648 0.841 1.00 0.00 ATOM 876 N LEU 172-6.059 8.860 0.937 1.00 0.00 ATOM 877 H LEU 172-5.415 9.510 1.285 1.00 0.00 ATOM 878 CA LEU 172-7.187 9.367 0.139 1.00 0.00 ATOM 879 HA LEU 172-7.358 10. 386 0.449 1.00 0.00 ATOM 880 CB LEU 172-6.840 9.377-1.353 1.00 0.00 ATOM 881 1HB LEU 172-7.738 9.136-1.904 1.00 0.00 ATOM 882 2HB LEU 172-6.111 8.601-1.546 1.00 0.00 ATOM 883 QB LEU 172-6.924 8.869-1.725 1.00 0.00 ATOM 884 CG LEU 172-6.298 10. 711-1. 889 1.00 0.00 ATOM 885 HG LEU 172-6.282 10. 674-2. 971 1.00 0.00 ATOM 886 QD1 LEU 172-7.401 12.143-1.375 1.00 0.00 ATOM 887 QD2 LEU 172-4.542 11.014-1.298 1.00 0.00 ATOM 888 CD1 LEU 172-7.191 11.869-1.474 1.00 0.00 ATOM 889 1HD1 LEU 172-6.636 12.538-0.833 1.00 0.00 ATOM 890 2HD1 LEU 172-8.049 11.489-0.940 1.00 0.00 ATOM 891 3HD1 LEU 172-7.519 12.403-2.353 1.00 0.00 ATOM 892 CD2 LEU 172-4.879 10.956-1.410 1.00 0.00 ATOM 893 1HD2 LEU 172-4.573 10.149-0.761 1.00 0.00 ATOM 894 2HD2 LEU 172-4.837 11.890-0.871 1.00 0.00 ATOM 895 3HD2 LEU 172-4.216 11.002-2.262 1.00 0.00 ATOM 896 QQD LEU 172-5.972 11.579-1.336 1.00 0.00 ATOM 897 C LEU 172-8.478 8.586 0.362 1.00 0.00 ATOM 898 O LEU 172-8. 887 7.796-0.485 1.00 0.00 ATOM 899 N PRO 173-9.150 8.803 1.499 1.00 0.00 ATOM 900 CD PRO 173-8.754 9.737 2.571 1.00 0.00 ATOM 901 CA PRO 173-10.402 8.113 1.800 1.00 0.00 ATOM 902 HA PRO 173-10.297 7.043 1.698 1.00 0.00 ATOM 903 CB PRO 173-10.667 8.468 3.265 1.00 0.00 ATOM 904 1HB PRO 173-10.282 7.686 3.903 1.00 0.00 ATOM 905 2HB PRO 173-11.731 8.577 3.423 1.00 0.00 ATOM 906 QB PRO 173-11.006 8.132 3.663 1.00 0.00 ATOM 907 CG PRO 173-9. 948 9.756 3.488 1.00 0.00 ATOM 908 1HG PRO 173-9.628 9.822 4.518 1.00 0.00 ATOM 909 2HG PRO 173-10.596 10.584 3.242 1.00 0.00 ATOM 910 QG PRO 173-10.112 10.203 3.880 1.00 0.00 ATOM 911 1HD PRO 173-7.882 9.374 3.095 1.00 0.00 ATOM 912 2HD PRO 173-8.570 10.724 2.172 1.00 0.00

ATOM 913 QD PRO 173-8.226 10.049 2.634 1.00 0.00 ATOM 914 C PRO 173-11.550 8.595 0.915 1.00 0.00 ATOM 915 O PRO 173-11.475 9.660 0.293 1.00 0.00 ATOM 916 N CYS 174-12.612 7.813 0.869 1.00 0.00 ATOM 917 H CYS 174-12.615 6.981 1.391 1.00 0.00 ATOM 918 CA CYS 174-13.785 8.162 0.078 1.00 0.00 ATOM 919 HA CYS 174-13.711 9.210-0.175 1.00 0.00 ATOM 920 CB CYS 174-13.852 7.341-1.208 1.00 0.00 ATOM 921 1HB CYS 174-13. 252 7.822-1.965 1.00 0.00 ATOM 922 2HB CYS 174-14. 877 7.299-1.544 1.00 0.00 ATOM 923 QB CYS 174-14.064 7.561-1.754 1.00 0.00 ATOM 924 SG CYS 174-13.261 5.628-1.038 1.00 0.00 ATOM 925 C CYS 174-15. 041 7.949 0.903 1.00 0.00 ATOM 926 O CYS 174-16.055 8.610 0.697 1.00 0.00 ATOM 927 N GLY 175-14.953 7.031 1.853 1.00 0.00 ATOM 928 H GLY 175-14.107 6.547 1.979 1.00 0.00 ATOM 929 CA GLY 175-16.069 6.751 2.726 1.00 0.00 ATOM 930 1HA GLY 175-16.491 5.792 2.470 1.00 0.00 ATOM 931 2HA GLY 175-16.820 7.518 2.598 1.00 0.00 ATOM 932 QA GLY 175-16.655 6.655 2.534 1.00 0.00 ATOM 933 C GLY 175-15.622 6.726 4.167 1.00 0.00 ATOM 934 O GLY 175-14.460 7.012 4.450 1.00 0.00 ATOM 935 N ILE 176-16.523 6.379 5.078 1.00 0.00 ATOM 936 H ILE 176-17.432 6.155 4.796 1.00 0.00 ATOM 937 CA ILE 176-16.177 6.317 6.493 1.00 0.00 ATOM 938 HA ILE 176-15.739 7.268 6.766 1.00 0.00 ATOM 939 CB ILE 176-17.431 6.087 7.379 1.00 0.00 ATOM 940 HB ILE 176-17.997 7.006 7.395 1.00 0.00 ATOM 941 QG2 ILE 176-18. 537 4.744 6.660 1.00 0.00 ATOM 942 CG2 ILE 176-18.326 5.001 6.796 1.00 0.00 ATOM 943 1HG2 ILE 176-18.608 5.268 5.789 1.00 0.00 ATOM 944 2HG2 ILE 176-19.212 4.902 7.404 1.00 0.00 ATOM 945 3HG2 ILE 176-17.791 4.062 6.785 1.00 0.00 ATOM 946 CG1 ILE 176-17.030 5.732 8.813 1. 00 0.00 ATOM 947 1HG1 ILE 176-15.953 5.776 8.901 1.00 0.00 ATOM 948 2HG1 ILE 176-17.363 4.729 9.035 1.00 0.00 ATOM 949 QG1 ILE 176-16.658 5.253 8.968 1.00 0.00 ATOM 950 QD1 ILE 176-17.761 6.879 10.100 1.00 0.00 ATOM 951 CD1 ILE 176-17.621 6.658 9.852 1.00 0.00 ATOM 952 1HD1 ILE 176-16.882 7.391 10.142 1.00 0.00 ATOM 953 2HD1 ILE 176-17.918 6.085 10.718 1.00 0.00 ATOM 954 3HD1 ILE 176-18.483 7.161 9.440 1.00 0.00 ATOM 955 C ILE 176-15.138 5.215 6.734 1.00 0.00 ATOM 956 O ILE 176-14.177 5.407 7.478 1.00 0.00 ATOM 957 N ASP 177-15.331 4.076 6.072 1.00 0.00 ATOM 958 H ASP 177-16.104 3.998 5.481 1.00 0.00 ATOM 959 CA ASP 177-14.410 2.949 6.183 1.00 0.00 ATOM 960 HA ASP 177-13.540 3.283 6.732 1.00 0.00 ATOM 961 CB ASP 177-15.059 1.785 6.938 1.00 0.00 ATOM 962 1HB ASP 177-15.699 1.239 6.262 1.00 0.00 ATOM 963 2HB ASP 177-15.649 2.175 7.753 1.00 0.00 ATOM 964 QB ASP 177-15. 674 1.707 7.008 1.00 0.00 ATOM 965 CG ASP 177-14.034 0.823 7.508 1.00 0.00 ATOM 966 OD1 ASP 177-14.442-0.233 8.031 1.00 0.00 ATOM 967 OD2 ASP 177-12.822 1. 119 7.423 1.00 0.00 ATOM 968 C ASP 177-13.971 2.490 4.794 1.00 0.00 ATOM 969 O ASP 177-13.847 1.294 4.517 1.00 0.00 ATOM 970 N LYS+ 178-13.740 3.452 3.911 1.00 0.00 ATOM 971 H LYS+ 178-13.852 4.388 4.184 1.00 0.00 ATOM 972 CA LYS+ 178-13.309 3.150 2.552 1.00 0.00 ATOM 973 HA LYS+ 178-12.888 2.155 2.554 1.00 0.00 ATOM 974 CB LYS+ 178-14.475 3.201 1.561 1.00 0.00 ATOM 975 1HB LYS+ 178-14.129 2.832 0.606 1.00 0.00 ATOM 976 2HB LYS+ 178-14.780 4.227 1.446 1.00 0.00 ATOM 977 QB LYS+ 178-14.454 3.530 1.026 1.00 0.00 ATOM 978 CG LYS+ 178-15.687 2.377 1.984 1.00 0.00 ATOM 979 1HG LYS+ 178-16.527 3.040 2.132 1.00 0.00 ATOM 980 2HG LYS+ 178-15. 459 1.871 2.912 1.00 0.00 ATOM 981 QG LYS+ 178-15.993 2.456 2.522 1.00 0.00 ATOM 982 CD LYS+ 178-16.056 1.336 0.935 1.00 0.00 ATOM 983 1HD LYS+ 178-15.481 1.525 0.040 1.00 0.00 ATOM 984 2HD LYS+ 178-17.109 1.424 0.713 1.00 0.00

ATOM 985 QD LYS+ 178-16.295 1.475 0.377 1.00 0.00 ATOM 986 CE LYS+ 178-15.770-0.082 1.419 1.00 0.00 ATOM 987 1HE LYS+ 178-16.507-0.353 2.161 1.00 0.00 ATOM 988 2HE LYS+ 178-14. 785-0.105 1.866 1.00 0.00 ATOM 989 QE LYS+ 178-15.646-0.229 2.014 1.00 0.00 ATOM 990 NZ LYS+ 178-15.819-1.069 0.302 1.00 0.00 ATOM 991 1HZ LYS+ 178-15.238-1.913 0.531 1.00 0.00 ATOM 992 2HZ LYS+ 178-15.441-0.647-0.578 1.00 0.00 ATOM 993 3HZ LYS+ 178-16.793-1.379 0.129 1.00 0.00 ATOM 994 QZ LYS+ 178-15.824-1.313 0.028 1.00 0.00 ATOM 995 C LYS+ 178-12.227 4.117 2.126 1.00 0. 00 ATOM 996 O LYS+ 178-12.338 5.328 2.329 1.00 0.00 ATOM 997 N PHE 179-11.181 3.570 1.542 1.00 0.00 ATOM 998 H PHE 179-11.164 2.599 1.414 1.00 0.00 ATOM 999 CA PHE 179-10.052 4.362 1.095 1.00 0.00 ATOM 1000 HA PHE 179-10.267 5.400 1.299 1.00 0.00 ATOM 1001 CB PHE 179-8.786 3.955 1.848 1.00 0.00 ATOM 1002 1HB PHE 179-8.035 4.695 1.674 1.00 0.00 ATOM 1003 2HB PHE 179-8.435 3.012 1.463 1.00 0.00 ATOM 1004 QB PHE 179-8.235 3.854 1.569 1.00 0.00 ATOM 1005 QD PHE 179-8.996 3.801 3.500 1.00 0.00 ATOM 1006 QE PHE 179-9. 321 3.584 5.929 1.00 0.00 ATOM 1007 QR PHE 179-9.224 3.649 5.201 1.00 0.00 ATOM 1008 CG PHE 179-8. 975 3. 817 3.334 1.00 0.00 ATOM 1009 CD1 PHE 179-9.427 2.626 3.884 1.00 0.00 ATOM 1010 1HD PHE 179-9.639 1.789 3.235 1.00 0.00 ATOM 1011 CE1 PHE 179-9.610 2.502 5.248 1.00 0. 00 ATOM 1012 1HE PHE 179-9.966 1.570 5.663 1.00 0.00 ATOM 1013 CZ PHE 179-9.339 3.570 6.080 1.00 0.00 ATOM 1014 HZ PHE 179-9.485 3.476 7.147 1.00 0.00 ATOM 1015 CE2 PHE 179-8.887 4.760 5.545 1.00 0.00 ATOM 1016 2HE PHE 179-8.676 5.598 6.194 1.00 0.00 ATOM 1017 CD2 PHE 179-8.708 4.881 4.180 1.00 0.00 ATOM 1018 2HD PHE 179-8.354 5.813 3.765 1.00 0.00 ATOM 1019 C PHE 179-9.816 4.183-0.387 1.00 0.00 ATOM 1020 O PHE 179-10. 500 3.399-1.044 1.00 0.00 ATOM 1021 N ARG+ 180-8.826 4.897-0.897 1.00 0.00 ATOM 1022 H ARG+ 180-8.312 5.490-0.306 1.00 0.00 ATOM 1023 CA ARG+ 180-8.462 4.818-2.300 1.00 0.00 ATOM 1024 HA ARG+ 180-8.920 3.934-2.718 1.00 0.00 ATOM 1025 CB ARG+ 180-8.965 6.050-3.055 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.489 6.079-4.023 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.682 6.932-2.508 1.00 0.00 ATOM 1028 QB ARG+ 180-8.585 6.506-3.265 1.00 0.00 ATOM 1029 CG ARG+ 180-10.471 6.078-3.256 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.953 6.018-2.292 1.00 0.00 ATOM 1031 2HG ARG+ 180-10.760 5.227-3.857 1.00 0.00 ATOM 1032 QG ARG+ 180-10.856 5.623-3.074 1.00 0.00 ATOM 1033 CD ARG+ 180-10.919 7.350-3.956 1.00 0.00 ATOM 1034 1HD ARG+ 180-11.932 7.213-4.307 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.270 7.526-4.802 1.00 0.00 ATOM 1036 QD ARG+ 180-11.101 7.370-4.554 1.00 0.00 ATOM 1037 NE ARG+ 180-10.874 8.517-3.073 1.00 0.00 ATOM 1038 HE ARG+ 180-11.595 8.616-2.417 1.00 0.00 ATOM 1039 CZ ARG+ 180-9.927 9.450-3.128 1.00 0.00 ATOM 1040 NH1 ARG+ 180-8.904 9.303-3.957 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-8.839 8.492-4.538 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-8.177 9.998-4.005 1.00 0.00 ATOM 1043 QH1 ARG+ 180-8.508 9.245-4.271 1.00 0.00 ATOM 1044 NH2 ARG+ 180-9.986 10.505-2.327 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-10.742 10.602-1.676 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-9.273 11.208-2.370 1.00 0.00 ATOM 1047 QH2 ARG+ 180-10.007 10.905-2.023 1.00 0.00 ATOM 1048 C ARG+ 180-6.949 4.718-2.458 1.00 0.00 ATOM 1049 O ARG+ 180-6.455 4.318-3.501 1.00 0.00 ATOM 1050 N GLY 181-6.209 5.099-1.426 1.00 0.00 ATOM 1051 H GLY 181-6.640 5.420-0.603 1.00 0.00 ATOM 1052 CA GLY 181-4. 765 5.059-1.522 1.00 0.00 ATOM 1053 1HA GLY 181-4.373 6.022-1.231 1.00 0.00 ATOM 1054 2HA GLY 181-4.495 4.873-2.551 1.00 0.00 ATOM 1055 QA GLY 181-4.434 5.448-1.891 1.00 0.00 ATOM 1056 C GLY 181-4.128 3.994-0.659 1.00 0.00

ATOM 1057 0 GLY 181-4.711 3.547 0.328 1.00 0.00 ATOM 1058 N VAL 182-2.914 3.603-1.037 1.00 0.00 ATOM 1059 H VAL 182-2.514 4.017-1.822 1.00 0.00 ATOM 1060 CA VAL 182-2.149 2.595-0.318 1.00 0.00 ATOM 1061 HA VAL 182-2.488 2.580 0.707 1.00 0.00 ATOM 1062 CB VAL 182-2.324 1.176-0.919 1.00 0.00 ATOM 1063 HB VAL 182-1. 519 1.011-1.622 1.00 0.00 ATOM 1064 QG1 VAL 182-2.191-0.128 0.427 1.00 0.00 ATOM 1065 QG2 VAL 182-3. 955 0.998-1.843 1.00 0.00 ATOM 1066 CG1 VAL 182-2.216 0.121 0.169 1.00 0.00 ATOM 1067 1HG1 VAL 182-2.348 0.586 1.136 1.00 0.00 ATOM 1068 2HG1 VAL 182-1.243-0.345 0.122 1.00 0.00 ATOM 1069 3HG1 VAL 182-2.981-0.626 0.021 1.00 0.00 ATOM 1070 CG2 VAL 182-3.643 1.032-1.667 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.921-0.011-1.709 1.00 0.00 ATOM 1072 2HG2 VAL 182-3.533 1.416-2.670 1.00 0.00 ATOM 1073 3HG2 VAL 182-4.412 1.589-1.151 1.00 0.00 ATOM 1074 QQG VAL 182-3.073 0.435-0.708 1.00 0.00 ATOM 1075 C VAL 182-0. 660 2.943-0.335 1.00 0.00 ATOM 1076 O VAL 182-0. 087 3.209-1.391 1.00 0.00 ATOM 1077 N GLU 183-0. 048 2.930 0.841 1.00 0.00 ATOM 1078 H GLU 183-0. 573 2.704 1.642 1.00 0.00 ATOM 1079 CA GLU 183 1.370 3.225 0.998 1.00 0.00 ATOM 1080 HA GLU 183 1.814 3.286 0.013 1.00 0.00 ATOM 1081 CB GLU 183 1.572 4.554 1.735 1.00 0.00 ATOM 1082 1HB GLU 183 1.849 5.311 1.016 1.00 0.00 ATOM 1083 2HB GLU 183 2.380 4.436 2.442 1.00 0.00 ATOM 1084 QB GLU 183 2.115 4.874 1.729 1.00 0.00 ATOM 1085 CG GLU 183 0.352 5.050 2.499 1.00 0.00 ATOM 1086 1HG GLU 183 0. 101 4.328 3.261 1.00 0.00 ATOM 1087 2HG GLU 183-0.473 5.150 1.812 1.00 0.00 ATOM 1088 QG GLU 183-0.186 4.739 2.537 1.00 0.00 ATOM 1089 CD GLU 183 0.594 6.390 3.162 1.00 0.00 ATOM 1090 OE1 GLU 183-0.157 7.345 2.871 1.00 0.00 ATOM 1091 OE2 GLU 183 1.551 6.496 3.952 1.00 0.00 ATOM 1092 C GLU 183 2.035 2.099 1.782 1.00 0.00 ATOM 1093 O GLU 183 2.082 2.131 3.006 1.00 0.00 ATOM 1094 N PHE 184 2.514 1.085 1.085 1.00 0.00 ATOM 1095 H PHE 184 2.430 1.090 0.113 1.00 0.00 ATOM 1096 CA PHE 184 3.126-0.060 1.745 1.00 0.00 ATOM 1097 HA PHE 184 3.004 0.079 2.807 1.00 0.00 ATOM 1098 CB PHE 184 2.421-1.359 1.340 1.00 0.00 ATOM 1099 1HB PHE 184 1.529-1.482 1.939 1.00 0.00 ATOM 1100 2HB PHE 184 3.085-2.189 1.540 1.00 0. 00 ATOM 1101 QB PHE 184 2.307-1.835 1.740 1.00 0.00 ATOM 1102 QD PHE 184 1.977-1.446-0.284 1.00 0.00 ATOM 1103 QE PHE 184 1.304-1.631-2.640 1.00 0.00 ATOM 1104 QR PHE 184 1.504-1.578-1. 933 1.00 0.00 ATOM 1105 CG PHE 184 2.023-1.437-0.117 1.00 0.00 ATOM 1106 CD1 PHE 184 2.639-2.344-0.963 1.00 0.00 ATOM 1107 1HD PHE 184 3.425-2.977-0.579 1.00 0.00 ATOM 1108 CE1 PHE 184 2.260-2.451-2.287 1.00 0.00 ATOM 1109 1HE PHE 184 2.752-3.164-2.933 1.00 0.00 ATOM 1110 CZ PHE 184 1.260-1.645-2.785 1.00 0.00 ATOM 1111 HZ PHE 184 0.958-1.734-3.817 1.00 0.00 ATOM 1112 CE2 PHE 184 0.639-0.732-1.959 1.00 0.00 ATOM 1113 2HE PHE 184-0. 145-0. 098-2.347 1.00 0.00 ATOM 1114 CD2 PHE 184 1.016-0.633-0.633 1.00 0.00 ATOM 1115 2HD PHE 184 0.528 0.084 0.011 1.00 0.00 ATOM 1116 C PHE 184 4.607-0.194 1.443 1.00 0.00 ATOM 1117 O PHE 184 5.054 0.059 0.331 1.00 0.00 ATOM 1118 N VAL 185 5.359-0.621 2.445 1.00 0.00 ATOM 1119 H VAL 185 4.936-0.818 3.308 1.00 0.00 ATOM 1120 CA VAL 185 6.788-0.822 2.302 1.00 0.00 ATOM 1121 HA VAL 185 7.080-0.508 1.307 1.00 0.00 ATOM 1122 CB VAL 185 7.584 0.006 3.337 1.00 0.00 ATOM 1123 HB VAL 185 7.770-0.618 4.204 1.00 0.00 ATOM 1124 QG1 VAL 185 9.236 0. 537 2.632 1.00 0.00 ATOM 1125 QG2 VAL 185 6. 613 1.514 3.901 1.00 0.00 ATOM 1126 CG1 VAL 185 8.919 0.434 2.766 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.688 0.299 3.512 1.00 0.00 ATOM 1128 2HG1 VAL 185 8.870 1.476 2.485 1.00 0.00

ATOM 1129 3HG1 VAL 185 9.149-0.163 1.897 1.00 0. 00 ATOM 1130 CG2 VAL 185 6.800 1.225 3.792 1.00 0.00 ATOM 1131 1HG2 VAL 185 7.120 1.508 4.784 1.00 0.00 ATOM 1132 2HG2 VAL 185 5.745 0.990 3. 809 1.00 0.00 ATOM 1133 3HG2 VAL 185 6.975 2.044 3.110 1. 00 0. 00 ATOM 1134 QQG VAL 185 7.925 1.026 3.266 1.00 0.00 ATOM 1135 C VAL 185 7.110-2.305 2.465 1.00 0.00 ATOM 1136 O VAL 185 6.962-2.869 3.547 1.00 0.00 ATOM 1137 N CYS 186 7.529-2.944 1.381 1.00 0.00 ATOM 1138 H CYS 186 7.614-2.450 0.533 1.00 0.00 ATOM 1139 CA CYS 186 7.851-4.364 1.418 1.00 0.00 ATOM 1140 HA CYS 186 7.627-4.722 2.414 1.00 0.00 ATOM 1141 CB CYS 186 6.993-5.140 0.409 1.00 0.00 ATOM 1142 1HB CYS 186 6.002-5.266 0.819 1.00 0.00 ATOM 1143 2HB CYS 186 7.434-6.111 0.251 1.00 0.00 ATOM 1144 QB CYS 186 6.718-5.688 0.535 1.00 0.00 ATOM 1145 SG CYS 186 6.822-4.351-1.222 1.00 0.00 ATOM 1146 C CYS 186 9.331-4.590 1.141 1.00 0.00 ATOM 1147 O CYS 186 9.874-4.061 0.181 1.00 0.00 ATOM 1148 N CYS 187 9.990-5.373 1.983 1.00 0.00 ATOM 1149 H CYS 187 9.513-5.777 2.741 1.00 0.00 ATOM 1150 CA CYS 187 11.419-5.635 1.804 1.00 0.00 ATOM 1151 HA CYS 187 11.836-4.799 1.270 1.00 0.00 ATOM 1152 CB CYS 187 12.131-5.764 3.154 1.00 0.00 ATOM 1153 1HB CYS 187 12.941-6.474 3.057 1.00 0.00 ATOM 1154 2HB CYS 187 11.429-6.128 3.889 1.00 0.00 ATOM 1155 QB CYS 187 12.185-6.301 3.473 1.00 0.00 ATOM 1156 SG CYS 187 12.831-4.205 3.782 1.00 0.00 ATOM 1157 C CYS 187 11.661-6.891 0.991 1.00 0.00 ATOM 1158 O CYS 187 10.896-7.848 1.081 1.00 0.00 ATOM 1159 N PRO 188 12.742-6.897 0.188 1.00 0.00 ATOM 1160 CD PRO 188 13.696-5.786 0.041 1.00 0.00 ATOM 1161 CA PRO 188 13.107-8.044-0.644 1.00 0.00 ATOM 1162 HA PRO 188 12.300-8.335-1.300 1.00 0.00 ATOM 1163 CB PRO 188 14.304-7.554-1.472 1.00 0.00 ATOM 1164 1HB PRO 188 14.144-7.800-2.512 1.00 0.00 ATOM 1165 2HB PRO 188 15.202-8.041-1.121 1.00 0.00 ATOM 1166 QB PRO 188 14. 673-7.920-1. 816 1.00 0.00 ATOM 1167 CG PRO 188 14.374-6.074-1.268 1.00 0.00 ATOM 1168 1HG PRO 188 13.863-5.568-2.073 1.00 0.00 ATOM 1169 2HG PRO 188 15.408-5.759-1.225 1.00 0.00 ATOM 1170 QG PRO 188 14.636-5.663-1.649 1.00 0.00 ATOM 1171 1HD PRO 188 13.181-4.839-0.005 1.00 0.00 ATOM 1172 2HD PRO 188 14.416-5.785 0.847 1.00 0.00 ATOM 1173 QD PRO 188 13.799-5. 312 0.421 1.00 0.00 ATOM 1174 C PRO 188 13.520-9.236 0.211 1.00 0.00 ATOM 1175 O PRO 188 14.469-9.146 0.993 1.00 0.00 ATOM 1176 N LEU 189 12.804-10.339 0.060 1.00 0.00 ATOM 1177 H LEU 189 12.059-10.344-0.580 1.00 0. 00 ATOM 1178 CA LEU 189 13.089-11.546 0.812 1.00 0.00 ATOM 1179 HA LEU 189 14.036-11.416 1.314 1.00 0.00 ATOM 1180 CB LEU 189 11.992-11.795 1.854 1.00 0.00 ATOM 1181 1HB LEU 189 11.227-12.404 1.394 1.00 0.00 ATOM 1182 2HB LEU 189 11. 557-10.844 2.120 1.00 0.00 ATOM 1183 QB LEU 189 11.392-11.624 1.757 1.00 0.00 ATOM 1184 CG LEU 189 12.445-12.494 3.143 1.00 0.00 ATOM 1185 HG LEU 189 11.754-12.249 3.936 1.00 0.00 ATOM 1186 QD1 LEU 189 12.436-14.360 2.924 1.00 0.00 ATOM 1187 QD2 LEU 189 14. 155-11. 903 3.657 1.00 0.00 ATOM 1188 CD1 LEU 189 12.437-14.003 2.967 1.00 0.00 ATOM 1189 1HD1 LEU 189 13.071-14.456 3.714 1.00 0.00 ATOM 1190 2HD1 LEU 189 12.808-14.251 1.982 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.429-14.373 3.076 1.00 0.00 ATOM 1192 CD2 LEU 189 13.828-12.015 3.560 1.00 0.00 ATOM 1193 1HD2 LEU 189 13-910-10. 954 3.382 1.00 0.00 ATOM 1194 2HD2 LEU 189 14.577-12.536 2.980 1. 00 0. 00 ATOM 1195 3HD2 LEU 189 13.979-12.219 4.608 1.00 0.00 ATOM 1196 QQD LEU 189 13.296-13.131 3.291 1.00 0.00 ATOM 1197 C LEU 189 13.188-12.736-0.140 1.00 0.00 ATOM 1198 OT1 LEU 189 12.352-12.821-1.065 1.00 0.00 ATOM 1199 OT2 LEU 189 14. 101-13. 567 0.042 1.00 0.00 TER

ENDMDL MODEL 11 ATOM 1 N SER 124 9.853 14.441-2.560 1.00 0.00 ATOM 2 CA SER 124 9.896 14.386-4.042 1.00 0.00 ATOM 3 HA SER 124 8.906 14.169-4.414 1.00 0.00 ATOM 4 CB SER 124 10.342 15.758-4.542 1.00 0.00 ATOM 5 1HB SER 124 9.695 16.077-5.346 1.00 0.00 ATOM 6 2HB SER 124 11.361 15.696-4.901 1.00 0.00 ATOM 7 QB SER 124 10.528 15.886-5.124 1.00 0.00 ATOM 8 OG SER 124 10.279 16.714-3.492 1.00 0.00 ATOM 9 HG SER 124 10.950 17.395-3.634 1.00 0.00 ATOM 10 C SER 124 10.859 13.307-4.509 1.00 0.00 ATOM 11 O SER 124 10.525 12.483-5.356 1.00 0.00 ATOM 12 1HT SER 124 8.953 14.057-2.212 1.00 0.00 ATOM 13 2HT SER 124 9.945 15.429-2.242 1.00 0.00 ATOM 14 3HT SER 124 10.638 13.886-2.159 1.00 0.00 ATOM 15 N ASP 125 12.047 13.329-3.929 1.00 0.00 ATOM 16 H ASP 125 12.232 14.018-3.255 1.00 0.00 ATOM 17 CA ASP 125 13.100 12.371-4.235 1.00 0.00 ATOM 18 HA ASP 125 13.219 12.322-5.306 1.00 0.00 ATOM 19 CB ASP 125 14.407 12.848-3.599 1.00 0.00 ATOM 20 1HB ASP 125 15.034 13.287-4.361 1.00 0.00 ATOM 21 2HB ASP 125 14.918 12.003-3.158 1. 00 0.00 ATOM 22 QB ASP 125 14.976 12.645-3.760 1.00 0.00 ATOM 23 CG ASP 125 14.168 13.884-2.518 1.00 0.00 ATOM 24 OD1 ASP 125 14.729 14.988-2.621 1.00 0.00 ATOM 25 OD2 ASP 125 13.381 13.600-1.587 1.00 0.00 ATOM 26 C ASP 125 12.743 10.992-3.700 1.00 0.00 ATOM 27 O ASP 125 12.493 10.059-4.464 1.00 0.00 ATOM 28 N ALA 126 12.718 10.874-2.378 1.00 0.00 ATOM 29 H ALA 126 12.927 11.660-1.826 1.00 0.00 ATOM 30 CA ALA 126 12.387 9.613-1.728 1.00 0.00 ATOM 31 HA ALA 126 12.891 8.821-2.264 1.00 0.00 ATOM 32 QB ALA 126 13.004 9.604 0.050 1.00 0.00 ATOM 33 CB ALA 126 12.886 9.606-0.290 1.00 0.00 ATOM 34 1HB ALA 126 12.623 10.539 0.187 1.00 0.00 ATOM 35 2HB ALA 126 13.959 9.487-0.281 1.00 0.00 ATOM 36 3HB ALA 126 12.428 8.787 0.245 1.00 0.00 ATOM 37 C ALA 126 10.885 9.361-1.772 1.00 0.00 ATOM 38 O ALA 126 10.157 9.706-0.841 1.00 0.00 ATOM 39 N LEU 127 10.428 8.767-2.863 1.00 0.00 ATOM 40 H LEU 127 11.056 8.526-3.573 1.00 0.00 ATOM 41 CA LEU 127 9.015 8.470-3.036 1.00 0.00 ATOM 42 HA LEU 127 8.489 8.860-2.181 1.00 0.00 ATOM 43 CB LEU 127 8.485 9.146-4.305 1.00 0.00 ATOM 44 1HB LEU 127 8.614 8.460-5.129 1.00 0.00 ATOM 45 2HB LEU 127 9.082 10. 026-4. 494 1.00 0.00 ATOM 46 QB LEU 127 8.848 9.243-4.812 1.00 0.00 ATOM 47 CG LEU 127 7.013 9.560-4.255 1.00 0.00 ATOM 48 HG LEU 127 6.409 8.695-4.017 1.00 0.00 ATOM 49 QD1 LEU 127 6.731 10.849-2.917 1.00 0.. 00 ATOM 50 QD2 LEU 127 6.458 10.218-5.927 1.00 0.00 ATOM 51 CD1 LEU 127 6.786 10.603-3.173 1.00 0.00 ATOM 52 1HD1 LEU 127 5.960 10.297-2.548 1.00 0.00 ATOM 53 2HD1 LEU 127 6.556 11.553-3.632 1.00 0.00 ATOM 54 3HD1 LEU 127 7.677 10.699-2.571 1.00 0.00 ATOM 55 CD2 LEU 127 6.564 10.092-5.606 1.00 0. 00 ATOM 56 1HD2 LEU 127 5. 698 10.724-5.475 1.00 0.00 ATOM 57 2HD2 LEU 127 6.311 9.265-6.252 1.00 0.00 ATOM 58 3HD2 LEU 127 7.364 10.665-6.052 1.00 0.00 ATOM 59 QQD LEU 127 6.595 10.534-4.422 1.00 0.00 ATOM 60 C LEU 127 8.795 6.963-3.108 1.00 0.00 ATOM 61 O LEU 127 7.703 6. 495-3.433 1.00 0.00 ATOM 62 N LEU 128 9.843 6.207-2.807 1.00 0.00 ATOM 63 H LEU 128 10.686 6.635-2.559 1.00 0.00 ATOM 64 CA LEU 128 9.770 4.760-2.841 1.00 0.00 ATOM 65 HA LEU 128 8.756 4.468-2.659 1.00 0.00 ATOM 66 CB LEU 128 10.189 4.256-4.226 1.00 0.00 ATOM 67 1HB LEU 128 11.249 4.057-4.205 1.00 0.00 ATOM 68 2HB LEU 128 10.004 5.046-4.940 1.00 0.00 ATOM 69 QB LEU 128 10.627 4.551-4.573 1.00 0.00 ATOM 70 CG LEU 128 9.466 2.994-4.704 1.00 0.00

ATOM 71 HG LEU 128 8.963 2.532-3.867 1.00 0.00 ATOM 72 QD1 LEU 128 8.161 3.439-5.983 1.00 0.00 ATOM 73 QD2 LEU 128 10.691 1.762-5.424 1.00 0.00 ATOM 74 CD1 LEU 128 8.411 3.352-5.738 1.00 0.00 ATOM 75 lAD1 LEU 128 8.329 4.428-5.810 1.00 0.00 ATOM 76 2HD1 LEU 128 7.458 2.940-5.439 1.00 0.00 ATOM 77 3HD1 LEU 128 8.694 2.949-6.699 1.00 0.00 ATOM 78 CD2 LEU 128 10.456 1.997-5.285 1.00 0.00 ATOM 79 1HD2 LEU 128 10.002 1.485-6.121 1.00 0.00 ATOM 80 2HD2 LEU 128 10.732 1.279-4.528 1.00 0.00 ATOM 81 3HD2 LEU 128 11.338 2.522-5.622 1.00 0.00 ATOM 82 QQD LEU 128 9.426 2.600-5.703 1.00 0.00 ATOM 83 C LEU 128 10.642 4.167-1.739 1.00 0.00 ATOM 84 O LEU 128 10.508 4.530-0.576 1.00 0.00 ATOM 85 N VAL 129 11.519 3.257-2.120 1.00 0.00 ATOM 86 H VAL 129 11.551 3.022-3.064 1.00 0.00 ATOM 87 CA VAL 129 12.431 2.590-1.181 1.00 0.00 ATOM 88 HA VAL 129 11.841 1.996-0.501 1.00 0.00 ATOM 89 CB VAL 129 13.408 1.652-1.930 1.00 0.00 ATOM 90 HB VAL 129 14.081 2.265-2.513 1.00 0.00 ATOM 91 QG1 VAL 129 14.444 0.646-0.724 1.00 0.00 ATOM 92 QG2 VAL 129 12.486 0.515-3.107 1.00 0.00 ATOM 93 CG1 VAL 129 14.245 0.838-0.955 1.00 0.00 ATOM 94 1HG1 VAL 129 13.633 0.540-0.115 1.00 0.00 ATOM 95 2HG1 VAL 129 15.071 1.439-0.602 1.00 0.00 ATOM 96 3HG1 VAL 129 14.626-0.041-1.453 1.00 0.00 ATOM 97 CG2 VAL 129 12.661 0.733-2.882 1.00 0.00 ATOM 98 1HG2 VAL 129 11.690 0. 502-2. 471 1.00 0.00 ATOM 99 2HG2 VAL 129 13.223-0.180-3.013 1.00 0.00 ATOM 100 3HG2 VAL 129 12.543 1.223-3.836 1.00 0.00 ATOM 101 QQG VAL 129 13.465 0.580-1.915 1.00 0.00 ATOM 102 C VAL 129 13.260 3.600-0.376 1.00 0.00 ATOM 103 O VAL 129 14.137 4.263-0.926 1.00 0.00 ATOM 104 N PRO 130 12.994 3.728 0.942 1.00 0.00 ATOM 105 CD PRO 130 11.973 3.005 1.696 1.00 0.00 ATOM 106 CA PRO 130 13.717 4.643 1.813 1.00 0.00 ATOM 107 HA PRO 130 13.985 5.545 1. 304 1.00 0.00 ATOM 108 CB PRO 130 12.702 4.959 2.925 1.00 0.00 ATOM 109 1HB PRO 130 12.378 5.985 2.830 1.00 0.00 ATOM 110 2HB PRO 130 13.173 4.820 3.887 1.00 0.00 ATOM 111 QB PRO 130 12.776 5.402 3.358 1.00 0.00 ATOM 112 CG PRO 130 11.553 4.008 2.738 1.00 0.00 ATOM 113 1HG PRO 130 10.683 4.553 2.400 1.00 0.00 ATOM 114 2HG PRO 130 11.339 3.507 3.670 1.00 0.00 ATOM 115 QG PRO 130 11.011 4.030 3.035 1.00 0.00 ATOM 116 1HD PRO 130 11.139 2.742 1.064 1.00 0.00 ATOM 117 2HD PRO 130 12.389 2.122 2.161 1.00 0.00 ATOM 118 QD PRO 130 11.764 2.432 1.612 1.00 0. 00 ATOM 119 C PRO 130 14.976 4.010 2.399 1.00 0.00 ATOM 120 O PRO 130 16.078 4.199 1.891 1.00 0.00 ATOM 121 N ASP 131 14.784 3.268 3.477 1.. 00 0.00 ATOM 122 H ASP 131 13.878 3.180 3.817 1.00 0.00 ATOM 123 CA ASP 131 15.880 2.593 4.172 1.00 0.00 ATOM 124 HA ASP 131 16.761 3.212 4.082 1.00 0.00 ATOM 125 CB ASP 131 15.529 2.439 5.659 1.00 0.00 ATOM 126 1HB ASP 131 14.664 1.802 5.755 1.00 0.00 ATOM 127 2HB ASP 131 15.301 3.411 6.070 1.00 0.00 ATOM 128 QB ASP 131 14.983 2.606 5.912 1.00 0.00 ATOM 129 CG ASP 131 16.657 1.839 6.472 1.00 0.00 ATOM 130 OD1 ASP 131 16.494 0.696 6.947 1.00 0.00 ATOM 131 OD2 ASP 131 17.696 2.507 6.631 1.00 0.00 ATOM 132 C ASP 131 16.174 1.223 3.544 1.00 0.00 ATOM 133 O ASP 131 16.819 1.133 2.501 1.00 0.00 ATOM 134 N LYS+ 132 15.701 0.157 4.186 1.00 0.00 ATOM 135 H LYS+ 132 15.203 0.289 5.020 1.00 0.00 ATOM 136 CA LYS+ 132 15.926-1.199 3.692 1.00 0.00 ATOM 137 HA LYS+ 132 16.662-1.143 2.903 1.00 0.00 ATOM 138 CB LYS+ 132 16.466-2.090 4.816 1.00 0.00 ATOM 139 1HB LYS+ 132 15.676-2.746 5.148 1.00 0.00 ATOM 140 2HB LYS+ 132 16.769-1.459 5.642 1.00 0.00 ATOM 141 QB LYS+ 132 16.223-2.103 5.395 1.00 0.00 ATOM 142 CG LYS+ 132 17.658-2.942 4.405 1.00 0.00

ATOM 143 1HG LYS+ 132 18.554-2.518 4.838 1.00 0.00 ATOM 144 2HG LYS+ 132 17.740-2.936 3.329 1.00 0.00 ATOM 145 QG LYS+ 132 18.147-2.727 4.083 1.00 0.00 ATOM 146 CD LYS+ 132 17. 510-4.380 4.883 1.00 0.00 ATOM 147 1HD LYS+ 132 16.582-4.471 5.429 1.00 0.00 ATOM 148 2HD LYS+ 132 18.339-4.617 5.535 1.00 0.00 ATOM 149 QD LYS+ 132 17. 461-4.544 5.482 1.00 0.00 ATOM 150 CE LYS+ 132 17. 501-5.357 3.715 1.00 0.00 ATOM 151 1HE LYS+ 132 18.483-5.363 3.262 1.00 0.00 ATOM 152 2HE LYS+ 132 16.774-5.022 2.989 1.00 0.00 ATOM 153 QE LYS+ 132 17.629-5. 193 3.125 1.00 0. 00 ATOM 154 NZ LYS+ 132 17.155-6.744 4.144 1.00 0.00 ATOM 155 1HZ LYS+ 132 18.023-7.289 4.331 1.00 0.00 ATOM 156 2HZ LYS+ 132 16.612-7.228 3.397 1.00 0.00 ATOM 157 3HZ LYS+ 132 16.581-6.719 5.012 1.00 0.00 ATOM 158 QZ LYS+ 132 17.072-7.079 4.246 1.00 0.00 ATOM 159 C LYS+ 132 14.643-1.802 3.127 1.00 0.00 ATOM 160 O LYS+ 132 14.669-2.843 2.468 1.00 0.00 ATOM 161 N CYS 133 13.524-1.147 3.389 1.00 0.00 ATOM 162 H CYS 133 13.569-0.326 3.918 1.00 0.00 ATOM 163 CA CYS 133 12.230-1.611 2.905 1.00 0.00 ATOM 164 HA CYS 133 12.327-2.650 2.630 1.00 0.00 ATOM 165 CB CYS 133 11. 163-1.472 3.997 1.00 0.00 ATOM 166 1HB CYS 133 10.213-1.259 3.527 1.00 0.00 ATOM 167 2HB CYS 133 11.426-0.644 4.637 1.00 0.00 ATOM 168 QB CYS 133 10.820-0.952 4.082 1.00 0.00 ATOM 169 SG CYS 133 10.933-2.937 5.061 1.00 0.00 ATOM 170 C CYS 133 11.808-0.805 1.684 1.00 0.00 ATOM 171 O CYS 133 12.393 0.223 1.388 1.00 0.00 ATOM 172 N LYS+ 134 10.782-1.269 0.993 1.00 0.00 ATOM 173 H LYS+ 134 10.343-2.097 1.288 1.00 0.00 ATOM 174 CA LYS+ 134 10.262-0.585-0.183 1.00 0.00 ATOM 175 HA LYS+ 134 10.978 0.167-0.482 1.00 0.00 ATOM 176 CB LYS+ 134 10.061-1.589-1.326 1.00 0.00 ATOM 177 1HB LYS+ 134 9.374-2.354-0.994 1.00 0.00 ATOM 178 2HB LYS+ 134 11.011-2.050-1.552 1.00 0.00 ATOM 179 QB LYS+ 134 10.193-2.202-1.273 1.00 0.00 ATOM 180 CG LYS+ 134 9.514-0.985-2.609 1.00 0.00 ATOM 181 1HG LYS+ 134 10.267-0.347-3.047 1.00 0.00 ATOM 182 2HG LYS+ 134 8.634-0.404-2.375 1.00 0.00 ATOM 183 QG LYS+ 134 9.451-0.376-2.711 1.00 0.00 ATOM 184 CD LYS+ 134 9.140-2.072-3.609 1.00 0.00 ATOM 185 1HD LYS+ 134 8.345-2.674-3.190.1.00 0.00 ATOM 186 2HD LYS+ 134 10.005-2.694-3.789 1.00 0.00 ATOM 187 QD LYS+ 134 9.175-2.684-3.490 1.00 0.00 ATOM 188 CE LYS+ 134 8.673-1.487-4.933 1.00 0.00 ATOM 189 1HE LYS+ 134 8.007-2.193-5.408 1.00 0.00 ATOM 190 2HE LYS+ 134 9.535-1.325-5.564 1.00 0.00 ATOM 191 QE LYS+ 134 8.771-1.759-5.486 1.00 0.00 ATOM 192 NZ LYS+ 134 7.958-0.194-4.748 1.00 0.00 ATOM 193 1HZ LYS+ 134 7.236-0.288-4.000 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.487 0.085-5.631 1.00 0.00 ATOM 195 3HZ LYS+ 134 8.628 0.553-4.474 1.00 0.00 ATOM 196 QZ LYS+ 134 7.784 0.116-4.702 1.00 0.00 ATOM 197 C LYS+ 134 8.947 0.084 0.182 1.00 0.00 ATOM 198 O LYS+ 134 7.955-0.590 0.431 1.00 0.00 ATOM 199 N PHE 135 8.952 1.403 0.247 1.00 0.00 ATOM 200 H PHE 135 9.781 1.889 0.060 1.00 0.00 ATOM 201 CA PHE 135 7.762 2.152 0.629 1.00 0.00 ATOM 202 HA PHE 135 7.149 1.499 1.235 1.00 0.00 ATOM 203 CB PHE 135 8.204 3.352 1.488 1.00 0.00 ATOM 204 1HB PHE 135 9.242 3.561 1.269 1.00 0.00 ATOM 205 2HB PHE 135 8.124 3.075 2.527 1.00 0.00 ATOM 206 QB PHE 135 8.683 3.318 1.898 1.00 0.00 ATOM 207 QD PHE 135 7.361 4.776 1.302 1.00 0.00 ATOM 208 QE PHE 135 6.170 6.914 1.078 1.00 0.00 ATOM 209 QR PHE 135 6.528 6.274 1.145 1.00 0.00 ATOM 210 CG PHE 135 7.441 4.634 1.317 1. 00 0.00 ATOM 211 CD1 PHE 135 6.294 4.878 2.051 1.00 0.00 ATOM 212 1HD PHE 135 5.920 4.119 2.724 1.00 0. 00 ATOM 213 CE1 PHE 135 5.626 6.078 1.930 1.00 0.00 ATOM 214 1HE PHE 135 4.730 6.259 2.506 1.00 0.00

ATOM 215 CZ PHE 135 6.098 7.047 1.065 1.00 0. 00 ATOM 216 HZ PHE 135 5.575 7.988 0.968 1.00 0.00 ATOM 217 CE2 PHE 135 7.238 6.814 0.327 1.00 0.00 ATOM 218 2HE PHE 135 7.610 7.570-0.350 1.00 0.00 ATOM 219 CD2 PHE 135 7.906 5.616 0.459 1.00 0.00 ATOM 220 2HD PHE 135 8.801 5.434-0.120 1.00 0.00 ATOM 221 C PHE 135 6.960 2.556-0.605 1.00 0.00 ATOM 222 O PHE 135 7.490 3.145-1.548 1.00 0.00 ATOM 223 N LEU 136 5.685 2.185-0.602 1.00 0.00 ATOM 224 H LEU 136 5.335 1.684 0.170 1.00 0.00 ATOM 225 CA LEU 136 4.792 2.460-1.716 1.00 0.00 ATOM 226 HA LEU 136 5.344 3.010-2.462 1.00 0.00 ATOM 227 CB LEU 136 4.274 1.156-2.329 1.00 0. 00 ATOM 228 1HB LEU 136 3.481 1.402-3.020 1.00 0.00 ATOM 229 2HB LEU 136 3.855 0.555-1.533 1.00 0.00 ATOM 230 QB LEU 136 3.668 0.978-2.277 1.00 0.00 ATOM 231 CG LEU 136 5.311 0.316-3.070 1.00 0.00 ATOM 232 HG LEU 136 6.141 0.945-3.350 1.00 0.00 ATOM 233 QD1 LEU 136 5.956-1.054-1.956 1.00 0.00 ATOM 234 QD2 LEU 136 4.563-0.413-4.634 1.00 0.00 ATOM 235 CD1 LEU 136 5.833-0.791-2.171 1.00 0.00 ATOM 236 1HD1 LEU 136 5.088-1.028-1.425 1.00 0.00 ATOM 237 2HD1 LEU 136 6.738-0.462-1.681 1.00 0.00 ATOM 238 3HD1 LEU 136 6.041-1.670-2.762 1.00 0.00 ATOM 239 CD2 LEU 136 4.707-0.272-4.335 1.00 0.00 ATOM 240 1HD2 LEU 136 5.071 0.267-5.196 1.00 0.00 ATOM 241 2HD2 LEU 136 3.630-0. 192-4.290 1.00 0.00 ATOM 242 3HD2 LEU 136 4.986-1. 313-4.416 1.00 0.00 ATOM 243 QQD LEU 136 5.259-0.733-3.295 1.00 0.00 ATOM 244 C LEU 136 3.606 3. 292-1. 260 1.00 0.00 ATOM 245 O LEU 136 2.589 2.752-0.832 1.00 0.00 ATOM 246 N HIS+ 137 3.737 4.598-1.371 1.00 0.00 ATOM 247 H HIS+ 137 4.570 4.965-1.732 1.00 0.00 ATOM 248 CA HIS+ 137 2.669 5.510-0.994 1.00 0.00 ATOM 249 HA HIS+ 137 1.967 4.981-0.352 1.00 0.00 ATOM 250 CB HIS+ 137 3.251 6.717-0.265 1.00 0.00 ATOM 251 1HB HIS+ 137 3.543 7.446-1.000 1.00 0.00 ATOM 252 2HB HIS+ 137 4.126 6.405 0.283 1.00 0.00 ATOM 253 QB HIS+ 137 3.835 6.925-0.359 1.00 0.00 ATOM 254 CG HIS+ 137 2.328 7.387 0.701 1.00 0. 00 ATOM 255 ND1 HIS+ 137 1.178 8.042 0.327 1.00 0.00 ATOM 256 CD2 HIS+ 137 2.405 7.509 2.044 1.00 0.00 ATOM 257 1HD HIS+ 137 0.830 8.135-0.597 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.590 8.536 1.398 1.00 0.00 ATOM 259 NE2 HIS+ 137 1.310 8.223 2.462 1.00 0. 00 ATOM 260 2HD HIS+ 137 3.182 7.108 2.679 1.00 0.00 ATOM 261 1HE HIS+ 137-0.333 9.097 1.405 1.00 0.00 ATOM 262 2HE HIS+ 137 0.941 8.172 3.378 1.00 0.00 ATOM 263 C HIS+ 137 1.975 5.988-2.258 1.00 0.00 ATOM 264 O HIS+ 137 2.480 6.880-2.940 1.00 0.00 ATOM 265 N GLN 138 0.847 5.392-2.592 1.00 0.00 ATOM 266 H GLN 138 0.490 4.671-2.025 1. 00 0.00 ATOM 267 CA GLN 138 0.138 5.780-3.801 1.00 0.00 ATOM 268 HA GLN 138 0.537 6.733-4.119 1.00 0.00 ATOM 269 CB GLN 138 0.377 4.751-4.911 1.00 0.00 ATOM 270 1HB GLN 138-0.262 4.986-5.748 1.00 0.00 ATOM 271 2HB GLN 138 0.118 3.772-4.537 1.00 0.00 ATOM 272 QB GLN 138-0.072 4.379-5.143 1.00 0.00 ATOM 273 CG GLN 138 1.819 4.708-5.407 1.00 0.00 ATOM 274 1HG GLN 138 2.390 5.452-4.869 1.00 0.00 ATOM 275 2HG GLN 138 1.831 4.940-6.461 1.00 0.00 ATOM 276 QG GLN 138 2.111 5.196-5.665 1.00 0.00 ATOM 277 CD GLN 138 2.470 3.353-5.202 1.00 0.00 ATOM 278 OE1 GLN 138 1.818 2.318-5.321 1.00 0.00 ATOM 279 NE2 GLN 138 3.764 3.346-4.895 1.00 0.00 ATOM 280 1HE2 GLN 138 4.232 4.204-4. 817 1.00 0.00 ATOM 281 2HE2 GLN 138 4.196 2.479-4. 756 1.00 0.00 ATOM 282 QE2 GLN 138 4.214 3.341-4. 787 1.00 0.00 ATOM 283 C GLN 138-1.353 5.941-3. 542 1.00 0.00 ATOM 284 O GLN 138-1t996 5.064-2.959 1.00 0.00 ATOM 285 N GLU 139-1. 895 7.068-3. 979 1.00 0.00 ATOM 286 H GLU 139-1.327 7.724-4. 431 1.00 0.00

ATOM 287 CA GLU 139-3.308 7.361-3.798 1.00 0.00 ATOM 288 HA GLU 139-3.669 6.746-2.987 1.00 0.00 ATOM 289 CB GLU 139-3.517 8.836-3.433 1.00 0.00 ATOM 290 1HB GLU 139-4.174 8.890-2.577 1.00 0.00 ATOM 291 2HB GLU 139-3.987 9.335-4.267 1.00 0.00 ATOM 292 QB GLU 139-4.080 9.112-3.422 1.00 0.00 ATOM 293 CG GLU 139-2.235 9.581-3.094 1.00 0.00 ATOM 294 1HG GLU 139-2.431 10.643-3.125 1.00 0.00 ATOM 295 2HG GLU 139-1.482 9.334-3.827 1.00 0.00 ATOM 296 QG GLU 139-1.956 9.988-3.476 1.00 0.00 ATOM 297 CD GLU 139-1.707 9.228-1.723 1.00 0.00 ATOM 298 OE1 GLU 139-0.570 8.721-1.643 1.00 0.00 ATOM 299 OE2 GLU 139-2.435 9.448-0.734 1.00 0.00 ATOM 300 C GLU 139-4.099 7.026-5.057 1.00 0.00 ATOM 301 O GLU 139-4.036 7.744-6.056 1.00 0.00 ATOM 302 N ARG+ 140-4.855 5.942-4.999 1.00 0.00 ATOM 303 H ARG+ 140-4.877 5.418-4.169 1.00 0.00 ATOM 304 CA ARG+ 140-5.674 5.519-6.123 1.00 0.00 ATOM 305 HA ARG+ 140-5.253 5.943-7.023 1.00 0.00 ATOM 306 CB ARG+ 140-5.672 3.987-6.234 1.00 0.00 ATOM 307 1HB ARG+ 140-6.222 3.582-5.396 1.00 0.00 ATOM 308 2HB ARG+ 140-4.653 3.635-6.186 1.00 0.00 ATOM 309 QB ARG+ 140-5.437 3.608-5.791 1.00 0.00 ATOM 310 CG ARG+ 140-6.300 3.455-7.514 1.00 0.00 ATOM 311 1HG ARG+ 140-7.302 3.853-7.602 1.00 0.00 ATOM 312 2HG ARG+ 140-6.343 2.378-7.461 1.00 0.00 ATOM 313 QG ARG+ 140-6.822 3.115-7.532 1.00 0.00 ATOM 314 CD ARG+ 140-5.500 3.858-8.742 1.00 0.00 ATOM 315 1HD ARG+ 140-4. 499 4.124-8.434 1.00 0.00 ATOM 316 2HD ARG+ 140-5. 977 4.719-9.195 1.00 0.00 ATOM 317 QD ARG+ 140-5.238 4.421-8.815 1.00 0.00 ATOM 318 NE ARG+ 140-5.427 2.783-9.731 1.00 0.00 ATOM 319 HE ARG+ 140-5.074 1.918-9.431 1.00 0.00 ATOM 320 CZ ARG+ 140-5.794 2.926-11.006 1.00 0.00 ATOM 321 NH1 ARG+ 140-6.333 4.067-11.418 1.00 0.00 ATOM 322 1HH1 ARG+ 140-6.471 4.827-10.767 1.00 0.00 ATOM 323 2HH1 ARG+ 140-6.619 4.179-12.369 1.00 0.00 ATOM 324 QH1 ARG+ 140-6.545 4.503-11.568 1.00 0.00 ATOM 325 NH2 ARG+ 140-5.647 1.919-11.860 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.260 1.050-11.551 1.00 0.00 ATOM 327 2HH2 ARG+ 140-5.924 2.027-12.816 1.00 0.00 ATOM 328 QH2 ARG+ 140-5.592 1.538-12.184 1.00 0.00 ATOM 329 C ARG+ 140-7.095 6.036-5.946 1.00 0.00 ATOM 330 O ARG+ 140-7.950 5.344-5.398 1.00 0.00 ATOM 331 N MET 141-7.343 7.260-6.405 1.00 0.00 ATOM 332 H MET 141-6.618 7.764-6.830 1.00 0.00 ATOM 333 CA MET 141-8.666 7.878-6.285 1.00 0. 00 ATOM 334 HA MET 141-9.029 7.687-5. 288,1.00 0.00 ATOM 335 CB MET 141-8.558 9.392-6.495 1.00 0.00 ATOM 336 1HB MET 141-8.693 9.606-7.546 1.00 0.00 ATOM 337 2HB MET 141-7.573 9.717-6.194 1.00 0.00 ATOM 338 QB MET 141-8.133 9.661-6.870 1.00 0.00 ATOM 339 CG MET 141-9.586 10.194-5.712 1.00 0.00 ATOM 340 1HG MET 141-9.453 9.992-4.659 1.00 0.00 ATOM 341 2HG MET 141-10.573 9.876-6.015 1.00 0.00 ATOM 342 QG MET 141-10. 013 9.934-5.337 1.00 0.00 ATOM 343 SD MET 141-9.448 11.973-5.983 1.00 0.00 ATOM 344 QE MET 141-7.323 12.269-5.799 1.00 0.00 ATOM 345 CE MET 141-7.679 12.219-5.829 1.00 0.00 ATOM 346 1HE MET 141-7.422 12.357-4.789 1.00 0.00 ATOM 347 2HE MET 141-7.388 13.096-6.390 1.00 0.00 ATOM 348 3HE MET 141-7.159 11.356-6.217 1.00 0. 00 ATOM 349 C MET 141-9.655 7.280-7.290 1.00 0.00 ATOM 350 O MET 141-10.517 7.980-7.821 1.00 0.00 ATOM 351 N ASP 142-9.520 5.986-7.536 1.00 0.00 ATOM 352 H ASP 142-8.816 5.490-7.076 1.00 0.00 ATOM 353 CA ASP 142-10.375 5.278-8.464 1.00 0.00 ATOM 354 HA ASP 142-11.043 5.990-8.924 1. 00 0.00 ATOM 355 CB ASP 142-9. 525 4.610-9.546 1. 00 0.00 ATOM 356 1HB ASP 142-10.180 4.165-10.269 1. 00 0.00 ATOM 357 2HB ASP 142-8.924 3.838-9.093 1. 00 0.00 ATOM 358 QB ASP 142-9.552 4.001-9.681 1. 00 0.00

ATOM 359 CG ASP 142-8.601 5.570-10.262 1.00 0.00 ATOM 360 OD1 ASP 142-8. 927 5.977-11.392 1.00 0.00 ATOM 361 OD2 ASP 142-7.522 5.882-9.712 1.00 0.00 ATOM 362 C ASP 142-11.184 4.210-7.744 1.00 0.00 ATOM 363 O ASP 142-12.403 4.123-7.894 1.00 0.00 ATOM 364 N VAL 143-10.489 3.379-6.977 1.00 0.00 ATOM 365 H VAL 143-9.520 3.491-6.909 1.00 0.00 ATOM 366 CA VAL 143-11.132 2.294-6.252 1.00 0.00 ATOM 367 HA VAL 143-12.059 2.066-6.759 1.00 0.00 ATOM 368 CB VAL 143-10.252 1.023-6.258 1.00 0.00 ATOM 369 HB VAL 143-9.661 1.016-5.351 1.00 0.00 ATOM 370 QG1 VAL 143-11.317-0.528-6.273 1.00 0.00 ATOM 371 QG2 VAL 143-9.076 1.020-7.727 1.00 0.00 ATOM 372 CG1 VAL 143-11.115-0.230-6.269 1.00 0.00 ATOM 373 1HG1 VAL 143-10.591-1.019-6.788 1.00 0.00 ATOM 374 2HG1 VAL 143-12.045-0.023-6.775 1.00 0.00 ATOM 375 3HG1 VAL 143-11.316-0.540-5.254 1.00 0.00 ATOM 376 CG2 VAL 143-9.300 1.021-7.446 1.00 0.00 ATOM 377 1HG2 VAL 143-8.300 1.245-7.106 1.00 0.00 ATOM 378 2HG2 VAL 143-9.615 1.768-8.159 1.00 0.00 ATOM 379 3HG2 VAL 143-9.313 0.048-7.914 1.00 0.00 ATOM 380 QQG VAL 143-10.196 0.246-7.000 1.00 0.00 ATOM 381 C VAL 143-11.449 2.706-4.812 1.00 0.00 ATOM 382 O VAL 143-10.813 3.600-4.259 1.00 0.00 ATOM 383 N CYS 144-12.441 2.051-4.217 1.00 0.00 ATOM 384 H CYS 144-12.912 1.350-4.713 1.00 0.00 ATOM 385 CA CYS 144-12.858 2.348-2.847 1.00 0.00 ATOM 386 HA CYS 144-12.032 2.825-2.331 1.00 0.00 ATOM 387 CB CYS 144-14.060 3.291-2.856 1.00 0.00 ATOM 388 1HB CYS 144-14.671 3.088-1.989 1.00 0.00 ATOM 389 2HB CYS 144-14.641 3.110-3.748 1.00 0.00 ATOM 390 QB CYS 144-14.656 3.099-2.869 1.00 0.00 ATOM 391 SG CYS 144-13.630 5.059-2.830 1.00 0.00 ATOM 392 C CYS 144-13.230 1.071-2.114 1.00 0.00 ATOM 393 O CYS 144-14.377 0.624-2.178 1.00 0.00 ATOM 394 N GLU 145-12.264 0.481-1.428 1.00 0.00 ATOM 395 H GLU 145-11.368 0.878-1.416 1.00 0.00 ATOM 396 CA GLU 145-12.498-0.752-0.703 1.00 0.00 ATOM 397 HA GLU 145-13.540-1.007-0.814 1.00 0.00 ATOM 398 CB GLU 145-11.658-1.866-1.311 1.00 0.00 ATOM 399 1HB GLU 145-11.465-2.612-0.557 1.00 0.00 ATOM 400 2HB GLU 145-10.715-1.451-1.641 1.00 0.00 ATOM 401 QB GLU 145-11.090-2.032-1.099 1.00 0.00 ATOM 402 CG GLU 145-12.333-2.546-2.493 1.00 0.00 ATOM 403 1HG GLU 145-11.849-3.495-2.673 1.00 0.00 ATOM 404 2HG GLU 145-12.228-1.918-3.364 1.00 0.00 ATOM 405 QG GLU 145-12.038-2.707-3.019 1.00 0.00 ATOM 406 CD GLU 145-13. 805-2.792-2.245 1.00 0.00 ATOM 407 OE1 GLU 145-14.618-2.484-3.135 1.00 0.00 ATOM 408 OE2 GLU 145-14.154-3.263-1.140 1.00 0.00 ATOM 409 C GLU 145-12.185-0.609 0.777 1.00 0.00 ATOM 410 O GLU 145-11.759 0.452 1.236 1.00 0.00 ATOM 411 N THR 146-12. 412-1.688 1.511 1.00 0.00 ATOM 412 H THR 146-12.757-2.494 1.073 1.00 0.00 ATOM 413 CA THR 146-12.176-1.718 2.945 1.00 0.00 ATOM 414 HA THR 146-12.591-0.818 3.375 1.00 0.00 ATOM 415 CB THR 146-12.886-2.935 3.541 1.00 0.00 ATOM 416 HB THR 146-12.200-3.770 3.545 1.00 0.00 ATOM 417 QG2 THR 146-13.481-2.676 5.300 1.00 0.00 ATOM 418 OG1 THR 146-14.010-3.290 2.750 1.00 0.00 ATOM 419 1HG THR 146-14.740-3.540 3.323 1.00 0.00 ATOM 420 CG2 THR 146-13.367-2.726 4.961 1.00 0.00 ATOM 421 1HG2 THR 146-12.554-2.908 5.648 1.00 0.00 ATOM 422 2HG2 THR 146-14.176-3.409 5.174 1.00 0.00 ATOM 423 3HG2 THR 146-13. 715-1.709 5.079 1.00 0.00 ATOM 424 C THR 146-10.679-1.774 3.248 1.00 0.00 ATOM 425 O THR 146-9.867-2.071 2.366 1.00 0.00 ATOM 426 N HIS+ 147-10.325-1.499 4.501 1.00 0.00 ATOM 427 H HIS+ 147-11.027-1.275 5.153 1.00 0.00 ATOM 428 CA HIS+ 147-8.931-1.522 4.945 1.00 0.00 ATOM 429 HA HIS+ 147-8.393-0.754 4.409 1.00 0.00 ATOM 430 CB HIS+ 147-8.863-1.226 6.446 1.00 0.00

ATOM 431 1HB HIS+ 147-8.844-2.161 6. 988 1.00 0.00 ATOM 432 2HB HIS+ 147-9.742-0.668 6.736 1.00 0.00 ATOM 433 QB HIS+ 147-9.293-1.415 6.862 1.00 0.00 ATOM 434 CG HIS+ 147-7.664-0.432 6.857 1.00 0.00 ATOM 435 ND1 HIS+ 147-7.685 0.937 7.010 1.00 0.00 ATOM 436 CD2 HIS+ 147-6. 403-0.824 7.160 1.00 0.00 ATOM 437 1HD HIS+ 147-8. 465 1.521 6.856 1.00 0.00 ATOM 438 CE1 HIS+ 147-6.491 1.354 7.391 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.693 0.306 7.491 1.00 0.00 ATOM 440 2HD HIS+ 147-6.019-1.836 7.123 1.00 0.00 ATOM 441 1HE HIS+ 147-6.212 2.381 7.584 1.00 0.00 ATOM 442 2HE HIS+ 147-4.716 0.352 7.582 1.00 0.00 ATOM 443 C HIS+ 147-8.281-2.875 4.661 1.00 0.00 ATOM 444 O HIS+ 147-7. 082-2.957 4.393 1.00 0.00 ATOM 445 N LEU 148-9.081-3.934 4.724 1.00 0.00 ATOM 446 H LEU 148-10.026-3.802 4.943 1.00 0.00 ATOM 447 CA LEU 148-8. 590-5. 285 4.479 1.00 0.00 ATOM 448 HA LEU 148-7.681-5.413 5.047 1.00 0.00 ATOM 449 CB LEU 148-9.619-6.314 4.955 1.00 0.00 ATOM 450 1HB LEU 148-10.293-6.521 4.137 1.00 0.00 ATOM 451 2HB LEU 148-10.186-5.877 5.765 1.00 0.00 ATOM 452 QB LEU 148-10.239-6.199 4.951 1.00 0.00 ATOM 453 CG LEU 148-9. 032-7.641 5.438 1.00 0.00 ATOM 454 HG LEU 148-7.958-7.548 5.506 1.00 0.00 ATOM 455 QD1 LEU 148-9.686-8.073 7.146 1.00 0.00 ATOM 456 QD2 LEU 148-9.423-9.019 4.219 1.00 0.00 ATOM 457 CD1 LEU 148-9.561-7.989 6.819 1.00 0.00 ATOM 458 1HD1 LEU 148-8.779-8.463 7.394 1.00 0.00 ATOM 459 2HD1 LEU 148-10.397-8.667 6.724 1.00 0.00 ATOM 460 3HD1 LEU 148-9.882-7.089 7.321 1.00 0. 00 ATOM 461 CD2 LEU 148-9.348-8.754 4.453 1.00 0.00 ATOM 462 1HD2 LEU 148-9.571-9.661 4.995 1.00 0.00 ATOM 463 2HD2 LEU 148-8.496-8.920 3.810 1.00 0.00 ATOM 464 3HD2 LEU 148-10.202-8.475 3.854 1.00 0.00 ATOM 465 QQD LEU 148-9.554-8.546 5.683 1.00 0.00 ATOM 466 C LEU 148-8.281-5.508 3.003 1.00 0.00 ATOM 467 O LEU 148-7.322-6.200 2.663 1.00 0.00 ATOM 468 N HIS+ 149-9.092-4.924 2.126 1.00 0.00 ATOM 469 H HIS+ 149-9.840-4.382 2.451 1.00 0.00 ATOM 470 CA HIS+ 149-8.888-5.077 0.690 1.00 0.00 ATOM 471 HA HIS+ 149-8. 858-6.136 0.479 1.00 0.00 ATOM 472 CB HIS+ 149-10.033-4.454-0.099 1.00 0.00 ATOM 473 1HB HIS+ 149-9.636-3.699-0.763 1.00 0.00 ATOM 474 2HB HIS+ 149-10.731-3.992 0.584 1.00 0.00 ATOM 475 QB HIS+ 149-10.183-3.846-0.090 1.00 0. 00 ATOM 476 CG HIS+ 149-10.784-5.448-0.929 1.00 0.00 ATOM 477 ND1 HIS+ 149-10. 165-6. 346-1.773 1.00 0.00 ATOM 478 CD2 HIS+ 149-12.112-5.680-1.045 1.00 0.00 ATOM 479 1HD HIS+ 149-9.196-6.427-1.918 1.00 0.00 ATOM 480 CE1 HIS+ 149-11.083-7.086-2.373 1.00 0.00 ATOM 481 NE2 HIS+ 149-12.275-6.701-1.948 1.00 0.00 ATOM 482 2HD HIS+ 149-12.903-5.147-0.531 1.00 0.00 ATOM 483 1HE HIS+ 149-10.891-7.873-3.088 1.00 0.00 ATOM 484 2HE HIS+ 149-13.126-6.940-2.376 1.00 0.00 ATOM 485 C HIS+ 149-7. 564-4.469 0.264 1.00 0.00 ATOM 486 O HIS+ 149-6.751-5.140-0.361 1.00 0.00 ATOM 487 N TRP 150-7. 343-3.204 0.617 1.00 0.00 ATOM 488 H TRP 150-8. 029-2.719 1.125 1.00 0.00 ATOM 489 CA TRP 150-6. 090-2.529 0.274 1. 00 0.00 ATOM 490 HA TRP 150-5.966-2.569-0.799 1.00 0.00 ATOM 491 CB TRP 150-6.097-1.075 0.738 1.00 0.00 ATOM 492 1HB TRP 150-5. 122-0.647 0.551 1.00 0.00 ATOM 493 2HB TRP 150-6. 293-1.048 1.799 1.00 0.00 ATOM 494 QB TRP 150-5.707-0.848 1.175 1.00 0.00 ATOM 495 CG TRP 150-7. 114-0.210 0.066 1.00 0.00 ATOM 496 CD1 TRP 150-7. 618 0.961 0.545 1.00 0.00 ATOM 497 CD2 TRP 150-7. 748-0.431-1.200 1.00 0.00 ATOM 498 CE3 TRP 150-7.664-1.432-2.172 1.00 0.00 ATOM 499 CE2 TRP 150-8. 620 0.649-1.418 1.00 0.00 ATOM 500 NE1 TRP 150-8. 524 1.481-0.340 1.00 0.00 ATOM 501 HD TRP 150-7.336 1.403 1.490 1.00 0.00 ATOM 502 3HE TRP 150-7. 007-2.278-2.046 1.00 0.00

ATOM 503 CZ3 TRP 150-8.440-1. 326-3.304 1.00 0.00 ATOM 504 CZ2 TRP 150-9. 399 0.755-2.560 1.00 0.00 ATOM 505 1HE TRP 150-9.022 2.317-0.220 1.00 0.00 ATOM 506 3HZ TRP 150-8. 393-2.093-4. 062 1.00 0.00 ATOM 507 CH2 TRP 150-9.296-0.240-3.489 1.00 0.00 ATOM 508 2HZ TRP 150-10.068 1.589-2.722 1.00 0.00 ATOM 509 HH TRP 150-9.887-0.199-4.392 1.00 0.00 ATOM 510 C TRP 150-4. 923-3.243 0.910 1.00 0.00 ATOM 511 O TRP 150-3. 845-3.296 0.337 1.00 0.00 ATOM 512 N HIS+ 151-5.149-3.807 2.089 1.00 0.00 ATOM 513 H HIS+ 151-6.041-3.739 2.491 1.00 0.00 ATOM 514 CA HIS+ 151-4.108-4.543 2.780 1.00 0.00 ATOM 515 HA HIS+ 151-3.272-3.878 2.931 1.00 0.00 ATOM 516 CB HIS+ 151-4.620-5.048 4.138 1.00 0.00 ATOM 517 1HB HIS+ 151-5.462-5.705 3.970 1.00 0.00 ATOM 518 2HB HIS+ 151-4.946-4.203 4.725 1.00 0.00 ATOM 519 QB HIS+ 151-5.204-4.954 4.347 1.00 0.00 ATOM 520 CG HIS+ 151-3.603-5.801 4.947 1.00 0.00 ATOM 521 ND1 HIS+ 151-3.310-5.502 6.260 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.818-6.857 4.622 1.00 0.00 ATOM 523 1HD HIS+ 151-3.716-4.782 6.790 1.00 0.00 ATOM 524 CE1 HIS+ 151-2.390-6.341 6.705 1.00 0.00 ATOM 525 NE2 HIS+ 151-2.077-7.173 5.732 1.00 0.00 ATOM 526 2HD HIS+ 151-2.777-7.349 3.656 1.00 0.00 ATOM 527 1HE HIS+ 151-1.954-6.336 7.695 1.00 0.00 ATOM 528 2HE HIS+ 151-1.499-7.959 5.827 1.00 0.00 ATOM 529 C HIS+ 151-3.671-5.709 1.907 1.00 0.00 ATOM 530 O HIS+ 151-2.480-5.941 1.715 1.00 0.00 ATOM 531 N THR 152-4.650-6.427 1.375 1.00 0.00 ATOM 532 H THR 152-5.579-6.180 1.562 1.00 0.00 ATOM 533 CA THR 152-4.382-7.561 0.511 1.00 0.00 ATOM 534 HA THR 152-3.677-8.202 1.020 1.00 0.00 ATOM 535 CB THR 152-5.670-8.345 0.248 1.00 0.00 ATOM 536 HB THR 152-6.272-7.799-0.467 1.00 0.00 ATOM 537 QG2 THR 152-5.372-10.060-0.445 1.00 0.00 ATOM 538 OG1 THR 152-6.418-8.494 1.446 1.00 0.00 ATOM 539 1HG THR 152-6. 734-7.632 1.742 1.00 0.00 ATOM 540 CG2 THR 152-5.430-9.731-0.311 1.00 0.00 ATOM 541 1HG2 THR 152-4.972-9.651-1.288 1.00 0.00 ATOM 542 2HG2 THR 152-6.371-10.252-0.396 1.00 0.00 ATOM 543 3HG2 THR 152-4.774-10.277 0. 349 1.00 0.00 ATOM 544 C THR 152-3.751-7.105-0.796 1.00 0.00 ATOM 545 O THR 152-2.720-7.631-1.181 1.00 0.00 ATOM 546 N VAL 153-4.360-6.115-1.456 1.00 0.00 ATOM 547 H VAL 153.-5. 177-5.718-1.080 1.00 0.00 ATOM 548 CA VAL 153-3.828-5.593-2.718 1.00 0.00 ATOM 549 HA VAL 153-3.848-6.395-3.440 1.00 0.00 ATOM 550 CB VAL 153-4.682-4.423-3.258 1.00 0.00 ATOM 551 HB VAL 153-4.636-3.610-2.549 1.00 0.00 ATOM 552 QG1 VAL 153-4.013-3.808-4.906 1.00 0.00 ATOM 553 QG2 VAL 153-6.476-4.951-3.441 1.00 0.00 ATOM 554 CG1 VAL 153-4.141-3.924-4.590 1.00 0.00 ATOM 555 1HG1 VAL 153-3.062-3.974-4.582 1.00 0.00 ATOM 556 2HG1 VAL 153-4.455-2.903-4.748 1.00 0.00 ATOM 557 3HG1 VAL 153-4.522-4.546-5.387 1.00 0.00 ATOM 558 CG2 VAL 153-6.134-4.849-3.405 1.00 0.00 ATOM 559 1HG2 VAL 153-6.594-4.900-2.430 1.00 0.00 ATOM 560 2HG2 VAL 153-6.176-5.821-3.876 1.00 0.00 ATOM 561 3HG2 VAL 153-6.660-4.130-4.015 1.00 0.00 ATOM 562 QQG VAL 153-5.244-4.379-4.173 1.00 0.00 ATOM 563 C VAL 153-2.388-5.140-2.544 1.00 0.00 ATOM 564 O VAL 153-1.514-5.479-3.339 1.00 0.00 ATOM 565 N ALA 154-2.146-4. 391-1.487 1.00 0.00 ATOM 566 H ALA 154-2.890-4.166-0.881 1.00 0.00 ATOM 567 CA ALA 154-0.813-3.907-1.187 1.00 0.00 ATOM 568 HA ALA 154-0.458-3.337-2.033 1.00 0.00 ATOM 569 QB ALA 154-0.874-2.778 0.308 1.00 0.00 ATOM 570 CB ALA 154-0.863-2.995 0.022 1.00 0.00 ATOM 571 1HB ALA 154-0.273-2.110-0.172 1.00 0.00 ATOM 572 2HB ALA 154-0.463-3.513 0.880 1.00 0.00 ATOM 573 3HB ALA 154-1.886-2.710 0.217 1.00 0.00 ATOM 574 C ALA 154 0.141-5.068-0. 924 1.00 0.00

ATOM 575 O ALA 154 1.241-5.131-1.479 1.00 0.00 ATOM 576 N LYS+ 155-0. 289-5. 980-0.060 1.00 0.00 ATOM 577 H LYS+ 155-1. 174-5. 863 0.350 1.00 0.00 ATOM 578 CA LYS+ 155 0.512-7.141 0.310 1.00 0.00 ATOM 579 HA LYS+ 155 1.463-6.780 0.688 1.00 0.00 ATOM 580 CB LYS+ 155-0.194-7.937 1.414 1.00 0.00 ATOM 581 1HB LYS+ 155-1.154-8.264 1.041 1.00 0.00 ATOM 582 2HB LYS+ 155-0. 355-7.287 2.261 1.00 0.00 ATOM 583 QB LYS+ 155-0. 754-7. 776 1.651 1.00 0.00 ATOM 584 CG LYS+ 155 0.573-9.161 1.892 1.00 0.00 ATOM 585 1HG LYS+ 155 0.977-8.960 2.874 1.00 0.00 ATOM 586 2HG LYS+ 155 1.379-9.362 1.201 1.00 0.00 ATOM 587 QG LYS+ 155 1.178-9.161 2.037 1.00 0.00 ATOM 588 CD LYS+ 155-0. 332-10.382 1.967 1.00 0.00 ATOM 589 1HD LYS+ 155-1. 338-10. 087 1.699 1.00 0.00 ATOM 590 2HD LYS+ 155-0. 327-10. 763 2.977 1.00 0.00 ATOM 591 QD LYS+ 155-0. 832-10. 425 2.338 1.00 0.00 ATOM 592 CE LYS+ 155 0.128-11.481 1.020 1.00 0.00 ATOM 593 1HE LYS+ 155 0.148-11.085 0.014 1.00 0.00 ATOM 594 2HE LYS+ 155-0. 577-12. 299 1.068 1.00 0.00 ATOM 595 QE LYS+ 155-0.214-11.692 0.541 1.00 0.00 ATOM 596 NZ LYS+ 155 1.485-11. 987 1.370 1.00 0.00 ATOM 597 1HZ LYS+ 155 1.678-11.835 2.380 1.00 0.00 ATOM 598 2HZ LYS+ 155 2.216-11.485 0.810 1.00 0.00 ATOM 599 3HZ LYS+ 155 1.553-13.005 1.165 1.00 0.00 ATOM 600 QZ LYS+ 155 1.816-12.109 1.451 1.00 0.00 ATOM 601 C LYS+ 155 0.785-8.042-0.884 1.00 0.00 ATOM 602 O LYS+ 155 1.921-8.464-1.079 1.00 0.00 ATOM 603 N GLU 156-0.243-8.350-1.672 1.00 0.00 ATOM 604 H GLU 156-1.142-7.995-1.467 1.00 0.00 ATOM 605 CA GLU 156-0.061-9.216-2.829 1.00 0.00 ATOM 606 HA GLU 156 0.420-10. 116-2.472 1.00 0.00 ATOM 607 CB GLU 156-1. 398-9. 611-3.476 1.00 0.00 ATOM 608 1HB GLU 156-2.017-10.087-2.729 1.00 0.00 ATOM 609 2HB GLU 156-1.202-10.321-4.265 1.00 0.00 ATOM 610 QB GLU 156-1.609-10.204-3.497 1.00 0.00 ATOM 611 CG GLU 156-2. 189-8. 462-4.074 1.00 0.00 ATOM 612 1HG GLU 156-1.872-8.313-5.096 1.00 0.00 ATOM 613 2HG GLU 156-1.996-7.567-3.502 1.00 0.00 ATOM 614 QG GLU 156-1. 934-7. 940-4.299 1.00 0.00 ATOM 615 CD GLU 156-3.679-8.731-4.064 1.00 0.00 ATOM 616 OE1 GLU 156-4. 097-9. 716-3.420 1.00 0.00 ATOM 617 OE2 GLU 156-4.428-7.955-4.691 1.00 0.00 ATOM 618 C GLU 156 0.872-8.569-3.843 1.00 0.00 ATOM 619 O GLU 156 1.722-9.243-4.401 1.00 0.00 ATOM 620 N THR 157 0.736-7.262-4.055 1.00 0.00 ATOM 621 H THR 157 0.045-6.764-3.563 1.00 0.00 ATOM 622 CA THR 157 1.606-6.549-4.991 1.00 0.00 ATOM 623 HA THR 157 1.465-6.985-5.969 1.00 0.00 ATOM 624 CB THR 157 1.226-5.063-5.045 1.00 0.00 ATOM 625 HB THR 157 1.297-4.648-4.049 1.00 0.00 ATOM 626 QG2 THR 157 2.327-4.044-6.170 1.00 0.00 ATOM 627 OG1 THR 157-0. 104-4. 900-5.501 1.00 0.00 ATOM 628 1HG THR 157-0. 716-5. 311-4.872 1.00 0.00 ATOM 629 CG2 THR 157 2.115-4.239-5.954 1.00 0.00 ATOM 630 1HG2 THR 157 2.856-4.880-6.410 1.00 0.00 ATOM 631 2HG2 THR 157 2.609-3.472-5.376 1.00 0.00 ATOM 632 3HG2 THR 157 1. 514-3. 779-6.724 1.00 0.00 ATOM 633 C THR 157 3.076-6.708-4.588 1.00 0.00 ATOM 634 O THR 157 3.950-6.910-5.431 1.00 0.00 ATOM 635 N CYS 158 3.344-6.620-3.293 1.00 0.00 ATOM 636 H CYS 158 2.610-6.455-2.660 1.00 0.00 ATOM 637 CA CYS 158 4.705-6.759-2.792 1.00 0.00 ATOM 638 HA CYS 158 5.360-6.240-3.476 1.00 0.00 ATOM 639 CB CYS 158 4.823-6.109-1.414 1.00 0.00 ATOM 640 1HB CYS 158 5.671-6.517-0.897 1.00 0.00 ATOM 641 2HB CYS 158 3.932-6.329-0.850 1.00 0.00 ATOM 642 QB CYS 158 4.802-6.423-0.874 1.00 0.00 ATOM 643 SG CYS 158 5.011-4.289-1.471 1.00 0.00 ATOM 644 C CYS 158 5.130-8.231-2.739 1.00 0.00 ATOM 645 O CYS 158 6.259-8.565-3.102 1.00 0.00 ATOM 646 N SER 159 4.229-9. 101-2.281 1.00 0.00

ATOM 647 H SER 159 3.351-8.770-1.996 1.00 0.00 ATOM 648 CA SER 159 4.513-10.534-2.172 1. 00 0.00 ATOM 649 HA SER 159 5.465-10.637-1.672 1.00 0.00 ATOM 650 CB SER 159 3.443-11.229-1.332 1.00 0.00 ATOM 651 1HB SER 159 3.549-12.300-1.437 1.00 0.00 ATOM 652 2HB SER 159 2.465-10.928-1.681 1.00 0.00 ATOM 653 QB SER 159 3.007-11.614-1.559 1.00 0.00 ATOM 654 OG SER 159 3.568-10.886 0.043 1.00 0.00 ATOM 655 HG SER 159 4. 491-10.673 0.232 1.00 0.00 ATOM 656 C SER 159 4.617-11.216-3.539 1.00 0.00 ATOM 657 O SER 159 5.293-12.233-3.663 1.00 0.00 ATOM 658 N GLU 160 3.957-10.658-4.557 1.00 0.00 ATOM 659 H GLU 160 3.432-9.843-4.402 1.00 0.00 ATOM 660 CA GLU 160 4.009-11.226-5.904 1.00 0.00 ATOM 661 HA GLU 160 3.750-12.273-5.841 1.00 0.00 ATOM 662 CB GLU 160 3.027-10.509-6.838 1.00 0.00 ATOM 663 1HB GLU 160 3.537-9.680-7.310 1.00 0.00 ATOM 664 2HB GLU 160 2.204-10.126-6.254 1.00 0.00 ATOM 665 QB GLU 160 2.871-9.903-6.782 1.00 0.00 ATOM 666 CG GLU 160 2.461-11.398-7.933 1.00 0.00 ATOM 667 1HG GLU 160 1.673-12.007-7.515 1.00 0.00 ATOM 668 2HG GLU 160 3.249-12.035-8.306 1.00 0.00 ATOM 669 QG GLU 160 2.461-12.021-7.911 1.00 0.00 ATOM 670 CD GLU 160 1.895-10.603-9.091 1.00 0.00 ATOM 671 OE1 GLU 160 1.000-11.125-9.785 1.00 0.00 ATOM 672 OE2 GLU 160 2.348-9.459-9.302 1.00 0.00 ATOM 673 C GLU 160 5.429-11.095-6.433 1.00 0.00 ATOM 674 O GLU 160 5.903-11.904-7.231 1.00 0.00 ATOM 675 N LYS+ 161 6.110-10.078-5.928 1.00 0.00 ATOM 676 H LYS+ 161 5.674-9.499-5.272 1.00 0.00 ATOM 677 CA LYS+ 161 7.488-9.821-6.274 1.00 0.00 ATOM 678 HA LYS+ 161 7.684-10.265-7.240 1.00 0.00 ATOM 679 CB LYS+ 161 7.757-8.311-6.329 1.00 0.00 ATOM 680 IHB LYS+ 161 8. 086-7.982-5.354 1.00 0.00 ATOM 681 2HB LYS+ 161 6.836-7.805-6.573 1.00 0.00 ATOM 682 QB LYS+ 161 7.461-7.894-5.964 1.00 0.00 ATOM 683 CG LYS+ 161 8.814-7.913-7.352 1.00 0.00 ATOM 684 1HG LYS+ 161 8.322-7.458-8.202 1.00 0.00 ATOM 685 2HG LYS+ 161 9.339-8.799-7.673 1.00 0.00 ATOM 686 QG LYS+ 161 8.831-8.129-7.938 1.00 0.00 ATOM 687 CD LYS+ 161 9.819-6.924-6.778 1.00 0.00 ATOM 688 1HD LYS+ 161 9.787-6.979-5.700 1.00 0.00 ATOM 689 2HD LYS+ 161 9.549-5.928-7.098 1.00 0.00 ATOM 690 QD LYS+ 161 9.668-6.454-6.399 1.00 0.00 ATOM 691 CE LYS+ 161 11.235-7.228-7.254 1.00 0.00 ATOM 692 1HE LYS+ 161 11. 664-6. 323-7.661 1.00 0.00 ATOM 693 2HE LYS+ 161 11.187-7.980-8.028 1.00 0.00 ATOM 694 QE LYS+ 161 11.426-7.152-7.845 1.00 0. 00 ATOM 695 NZ LYS+ 161 12.107-7.726-6.151 1.00 0.00 ATOM 696 lHZ LYS+ 161 11.878-7.242-5.261 1.00 0.00 ATOM 697 2HZ LYS+ 161 13.107-7.554-6.378 1.00 0.00 ATOM 698 3HZ LYS+ 161 11.968-8.760-6.017 1.00 0.00 ATOM 699 QZ LYS+ 161 12.318-7.852-5.886 1.00 0.00 ATOM 700 C LYS+ 161 8.364-10.485-5.222 1.00 0.00 ATOM 701 O LYS+ 161 8.096-11.604-4.798 1.00 0.00 ATOM 702 N SER 162 9.397-9.799-4. 783 1.00 0.00 ATOM 703 H SER 162 9.565-8.908-5.136 1.00 0.00 ATOM 704 CA SER 162 10.272-10.348-3.767 1.00 0.00 ATOM 705 HA SER 162 9.891-11.322-3. 503 1.00 0.00 ATOM 706 CB SER 162 11.694-10.503-4.308 1.00 0.00 ATOM 707 1HB SER 162 12.071-11.482-4.042 1.00 0.00 ATOM 708 2HB SER 162 12.327-9.745-3.867 1.00 0.00 ATOM 709 QB SER 162 12.199-10.614-3.955 1.00 0.00 ATOM 710 OG SER 162 11.723-10.365-5.726 1.00 0.00 ATOM 711 HG SER 162 11.614-11.238-6.128 1.00 0.00 ATOM 712 C SER 162 10.275-9.473-2.518 1.00 0.00 ATOM 713 O SER 162 11.334-9.087-2.039 1.00 0.00 ATOM 714 N THR 163 9.091-9.146-1.995 1.00 0.00 ATOM 715 H THR 163 8.263-9.469-2.420 1.00 0.00 ATOM 716 CA THR 163 9.002-8.322-0.791 1.00 0.00 ATOM 717 HA THR 163 9.901-8.490-0.210 1.00 0.00 ATOM 718 CB THR 163 8.913-6.833-1.129 1.00 0.00

ATOM 719 HB THR 163 8.714-6.295-0.207 1.00 0.00 ATOM 720 QG2 THR 163 10.470-6.111-1.881 1.00 0.00 ATOM 721 OG1 THR 163 7.859-6.586-2.037 1.00 0.00 ATOM 722 1HG THR 163 7.572-7.421-2.435 1.00 0.00 ATOM 723 CG2 THR 163 10.170-6.249-1.737 1.00 0.00 ATOM 724 1HG2 THR 163 9.922-5.732-2.651 1.00 0.00 ATOM 725 2HG2 THR 163 10.870-7.046-1.950 1.00 0.00 ATOM 726 3HG2 THR 163 10.618-5.555-1.040 1.00 0.00 ATOM 727 C THR 163 7.798-8.714 0.067 1.00 0.00 ATOM 728 O THR 163 6.871-9.379-0.394 1.00 0.00 ATOM 729 N ASN 164 7.818-8.280 1.317 1.00 0.00 ATOM 730 H ASN 164 8.591-7.751 1.619 1.00 0.00 ATOM 731 CA ASN 164 6.731-8.561 2.261 1.00 0.00 ATOM 732 HA ASN 164 5.903-8.979 1.701 1.00 0.00 ATOM 733 CB ASN 164 7.192-9.570 3.321 1.00 0.00 ATOM 734 1HB ASN 164 6.963-10.569 2.982 1.00 0.00 ATOM 735 2HB ASN 164 6.668-9.379 4.246 1.00 0.00 ATOM 736 QB ASN 164 6.816-9.974 3.614 1.00 0.00 ATOM 737 CG ASN 164 8.682-9.484 3.587 1.00 0.00 ATOM 738 OD1 ASN 164 9.364-10.496 3.679 1.00 0.00 ATOM 739 ND2 ASN 164 9.189-8.266 3.724 1.00 0.00 ATOM 740 1HD2 ASN 164 8.575-7.503 3.666 1.00 0.00 ATOM 741 2HD2 ASN 164 10.155-8.176 3.820 1.00 0.00 ATOM 742 QD2 ASN 164 9.365-7.840 3.743 1.00 0.00 ATOM 743 C ASN 164 6.276-7.277 2.949 1. 00 0.00 ATOM 744 O ASN 164 7.106-6.498 3.418 1.00 0.00 ATOM 745 N LEU 165 4.965-7.052 3.001 1.00 0.00 ATOM 746 H LEU 165 4.354-7.705 2.607 1.00 0.00 ATOM 747 CA LEU 165 4.413-5.846 3.629 1.00 0.00 ATOM 748 HA LEU 165 4.898-4.983 3.193 1.00 0.00 ATOM 749 CB LEU 165 2.908-5.742 3.386 1.00 0.00 ATOM 750 1HB LEU 165 2.413-5.660 4.342 1.00 0.00 ATOM 751 2HB LEU 165 2.573-6.646 2.900 1.00 0.00 ATOM 752 QB LEU 165 2.493-6.153 3.621 1.00 0.00 ATOM 753 CG LEU 165 2.480-4.556 2.545 1.00 0.00 ATOM 754 HG LEU 165 2. 932-3.657 2.940 1.00 0.00 ATOM 755 QD1 LEU 165 3.064-4.776 0.782 1.00 0.00 ATOM 756 QD2 LEU 165 0.615-4.353 2.612 1.00 0.00 ATOM 757 CD1 LEU 165 2.952-4.734 1.123 1.00 0.00 ATOM 758 1HD1 LEU 165 3.362-5.724 1.000 1.00 0.00 ATOM 759 2HD1 LEU 165 3.711-3.998 0.900 1.00 0.00 ATOM 760 3HD1 LEU 165 2.117-4.605 0.447 1.00 0.00 ATOM 761 CD2 LEU 165 0.973-4.391 2.600 1.00 0. 00 ATOM 762 1HD2 LEU 165 0.633-4.507 3.619 1.00 0.00 ATOM 763 2HD2 LEU 165 0.506-5.141 1.977 1.00 0. 00 ATOM 764 3HD2 LEU 165 0.706-3.409 2.241 1.00 0.00 ATOM 765 QQD LEU 165 1.840-4.564 1.697 1.00 0.00 ATOM 766 C LEU 165 4.663-5.826 5.122 1.00 0.00 ATOM 767 O LEU 165 4.318-6.767 5.834 1.00 0.00 ATOM 768 N HIS+ 166 5.246-4.736 5.583 1.00 0. 00 ATOM 769 H HIS+ 166 5.484-4.018 4.958 1.00 0.00 ATOM 770 CA HIS+ 166 5.529-4.560 6.992 1.00 0.00 ATOM 771 HA HIS+ 166 5.201-5.448 7.511 1.00 0.00 ATOM 772 CB HIS+ 166 7.036-4.375 7.208 1.00 0.00 ATOM 773 1HB HIS+ 166 7.361-3.492 6.674 1.00 0.00 ATOM 774 2HB HIS+ 166 7.557-5.235 6.818 1.00 0.00 ATOM 775 QB HIS+ 166 7.459-4.364 6.746 1.00 0.00 ATOM 776 CG HIS+ 166 7.429-4.213 8.642 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.410-5.244 9.557 1.00 0.00 ATOM 778 CD2 HIS+ 166 7.845-3.121 9.318 1.00 0.00 ATOM 779 1HD HIS+ 166 7.145-6.170 9.372 1.00 0.00 ATOM 780 CE1 HIS+ 166 7.798-4.788 10.736 1.00 0. 00 ATOM 781 NE2 HIS+ 166 8.068-3.498 10.616 1.00 0.00 ATOM 782 2HD HIS+ 166 7.962-2.122 8.909 1.00 0.00 ATOM 783 1HE HIS+ 166 7.880-5.369 11.643 1.00 0.00 ATOM 784 2HE HIS+ 166 8.179-2.877 11.366 1.00 0. 00 ATOM 785 C HIS+ 166 4.754-3.356 7.528 1.00 0.00 ATOM 786 O HIS+ 166 4.057-3.457 8.538 1. 00 0. 00 ATOM 787 N ASP 167 4.876-2.222 6.840 1.00 0.00 ATOM 788 H ASP 167 5.444-2.209 6.038 1.00 0.00 ATOM 789 CA ASP 167 4.186-0.995 7.252 1.00 0.00 ATOM 790 HA ASP 167 3.658-1.209 8.169 1.00 0.00

ATOM 791 CB ASP 167 5.186 0.142 7.510 1.00 0.00 ATOM 792 1HB ASP 167 4.770 0.811 8.250 1.00 0.00 ATOM 793 2HB ASP 167 5.341 0.687 6.592 1.00 0.00 ATOM 794 QB ASP 167 5.056 0.749 7.421 1.00 0.00 ATOM 795 CG ASP 167 6.533-0.340 8.008 1.00 0.00 ATOM 796 OD1 ASP 167 7.364-0.756 7.171 1.00 0.00 ATOM 797 OD2 ASP 167 6.762-0.296 9.233 1.00 0.00 ATOM 798 C ASP 167 3.178-0.542 6. 198 1.00 0.00 ATOM 799 O ASP 167 3.495 0.265 5.328 1.00 0.00 ATOM 800 N TYR 168 1.968-1.069 6. 278 1.00 0.00 ATOM 801 H TYR 168 1.778-1.709 6.996 1.00 0.00 ATOM 802 CA TYR 168 0.900-0.721 5.336 1.00 0.00 ATOM 803 HA TYR 168 1.358-0.403 4.403 1.00 0.00 ATOM 804 CB TYR 168 0.023-1.948 5.073 1.00 0.00 ATOM 805 1HB TYR 168 0.441-2.514 4.255 1.00 0.00 ATOM 806 2HB TYR 168-0.972-1.620 4.811 1.00 0.00 ATOM 807 QB TYR 168-0.265-2.067 4.533 1.00 0.00 ATOM 808 QD TYR 168-0.099-2.969 6.409 1.00 0.00 ATOM 809 QE TYR 168-0.267-4.441 8.368 1.00 0.00 ATOM 810 QR TYR 168-0.183-3.705 7.389 1.00 0.00 ATOM 811 CG TYR 168-0.088-2.865 6.271 1.00 0.00 ATOM 812 CD1 TYR 168 0.717-3.991 6.388 1.00 0.00 ATOM 813 1HD TYR 168 1.424-4.216 5.604 1.00 0.00 ATOM 814 CE1 TYR 168 0.625-4.821 7.488 1.00 0.00 ATOM 815 1HE TYR 168 1.261-5.691 7.562 1.00 0.00 ATOM 816 CZ TYR 168-0.279-4.530 8.487 1.00 0.00 ATOM 817 CE2 TYR 168-1.088-3.418 8.393 1.00 0.00 ATOM 818 2HE TYR 168-1.796-3.190 9.175 1.00 0.00 ATOM 819 CD2 TYR 168-0. 990-2.594 7.291 1.00 0.00 ATOM 820 2HD TYR 168-1.622-1.721 7.214 1.00 0.00 ATOM 821 OH TYR 168-0.376-5.353 9.582 1.00 0.00 ATOM 822 HH TYR 168 0.309-5.122 10.218 1.00 0.00 ATOM 823 C TYR 168 0.036 0.420 5.869 1.00 0.00 ATOM 824 O TYR 168-0.162 0.553 7.076 1.00 0.00 ATOM 825 N GLY 169-0.495 1.215 4.956 1.00 0.00 ATOM 826 H GLY 169-0.315 1.044 4.008 1.00 0.00 ATOM 827 CA GLY 169-1.353 2.321 5.321 1.00 0.00 ATOM 828 1HA GLY 169-0.759 3.222 5.403 1.00 0.00 ATOM 829 2HA GLY 169-1. 818 2.112 6.274 1.00 0.00 ATOM 830 QA GLY 169-1.288 2.667 5.838 1.00 0.00 ATOM 831 C GLY 169-2.417 2.526 4.274 1.00 0.00 ATOM 832 O GLY 169-2.264 2.058 3.145 1.00 0.00 ATOM 833 N MET 170-3.494 3.202 4.628 1.00 0.00 ATOM 834 H MET 170-3.566 3.546 5.543 1.00 0.00 ATOM 835 CA MET 170-4.580 3.442 3.685 1.00 0.00 ATOM 836 HA MET 170-4.170 3.382 2.681 1.00 0.00 ATOM 837 CB MET 170-5.679 2.386 3.848 1.00 0.00 ATOM 838 1HB MET 170-6.568 2.730 3.341 1.00 0.00 ATOM 839 2HB MET 170-5.898 2.272 4.900 1.00 0.00 ATOM 840 QB MET 170-6.233 2.501 4.120 1.00 0.00 ATOM 841 CG MET 170-5.307 1.023 3.287 1.00 0.00 ATOM 842 1HG MET 170-4.563 1.158 2.515 1.00 0.00 ATOM 843 2HG MET 170-6.190 0.572 2.859 1.00 0.00 ATOM 844 QG MET 170-5.376 0.865 2.687 1.00 0.00 ATOM 845 SD MET 170-4.642-0. 088 4.542 1.00 0.00 ATOM 846 QE MET 170-3.297-1.289 3.375 1.00 0.00 ATOM 847 CE MET 170-3.522-1.087 3.571 1.00 0.00 ATOM 848 1HE MET 170-4.090-1.709 2.895 1.00 0.00 ATOM 849 2HE MET 170-2.936-1.713 4.228 1.00 0.00 ATOM 850 3HE MET 170-2.865-0.445 3.004 1.00 0.00 ATOM 851 C MET 170-5.164 4.829 3.902 1.00 0.00 ATOM 852 O MET 170-5.709 5.123 4.966 1.00 0.00 ATOM 853 N LEU 171-5.042 5.681 2.897 1.00 0.00 ATOM 854 H LEU 171-4.591 5.390 2.074 1.00 0.00 ATOM 855 CA LEU 171-5.554 7.043 2.995 1.00 0.00 ATOM 856 HA LEU 171-5.951 7.170 3.991 1.00 0.00 ATOM 857 CB LEU 171-4.432 8. 061 2.780 1.00 0.00 ATOM 858 1HB LEU 171-4.547 8.848 3.509 1.00 0.00 ATOM 859 2HB LEU 171-4.548 8.489 1.794 1.00 0.00 ATOM 860 QB LEU 171-4.547 8.668 2.651 1.00 0.00 ATOM 861 CG LEU 171-3.015 7.509 2.897 1. 00 0.00 ATOM 862 HG LEU 171-3.029 6.615 3.505 1.00 0.00

ATOM 863 QD1 LEU 171-2.344 7.050 1.201 1.00 0.00 ATOM 864 QD2 LEU 171-1.895 8.763 3.731 1.00 0.00 ATOM 865 CD1 LEU 171-2.474 7.138 1.526 1.00 0.00 ATOM 866 1HD1 LEU 171-1.427 6.886 1.610 1.00 0.00 ATOM 867 2HD1 LEU 171-2.588 7.976 0.852 1.00 0.00 ATOM 868 3HD1 LEU 171-3. 017 6.289 1.141 1.00 0.00 ATOM 869 CD2 LEU 171-2.111 8.524 3.572 1.00 0.00 ATOM 870 1HD2 LEU 171-2.675 9.079 4.305 1.00 0.00 ATOM 871 2HD2 LEU 171-1.717 9.203 2.829 1.00 0.00 ATOM 872 3HD2 LEU 171-1.294 8.009 4.059 1.00 0.00 ATOM 873 QQD LEU 171-2. 119 7.907 2.466 1.00 0.00 ATOM 874 C LEU 171-6. 667 7.300 1.990 1.00 0.00 ATOM 875 O LEU 171-7.223 6.367 1.410 1.00 0.00 ATOM 876 N LEU 172-6.972 8.586 1.798 1.00 0.00 ATOM 877 H LEU 172-6. 472 9.263 2.301 1.00 0.00 ATOM 878 CA LEU 172-8.012 9.034 0.868 1.00 0.00 ATOM 879 HA LEU 172-8.191 10.080 1.061 1.00 0.00 ATOM 880 CB LEU 172-7.538 8.878-0.581 1.00 0.00 ATOM 881 1HB LEU 172-8.345 8.442-1.151 1.00 0.00 ATOM 882 2HB LEU 172-6. 703 8. 193-0.595 1.00 0.00 ATOM 883 QB LEU 172-7.524 8.317-0.873 1.00 0.00 ATOM 884 CG LEU 172-7.112 10.175-1.271 1.00 0.00 ATOM 885 HG LEU 172-7.830 10.950-1.049 1.00 0.00 ATOM 886 QD1 LEU 172-5.432 10.741-0.643 1.00 0.00 ATOM 887 QD2 LEU 172-7.062 9.940-3.135 1.00 0.00 ATOM 88$ CD1 LEU 172-5.755 10.633-0.762 1.00 0.00 ATOM 889 1HD1 LEU 172-5.813 11.668-0.459 1.00 0.00 ATOM 890 2HD1 LEU 172-5.021 10.530-1.550 1.00 0.00 ATOM 891 3HD1 LEU 172-5.462 10.027 0.081 1.00 0.00 ATOM 892 CD2 LEU 172-7.073 9.985-2.778 1.00 0.00 ATOM 893 1HD2 LEU 172-7.255 8.947-3.015 1.00 0.00 ATOM 894 2HD2 LEU 172-6.100 10.273-3.150 1.00 0.00 ATOM 895 3HD2 LEU 172-7.831 10.600-3.239 1.00 0.00 ATOM 896 QQD LEU 172-6.247 10.341-1.889 1.00 0.00 ATOM 897 C LEU 172-9.323 8.274 1.063 1.00 0.00 ATOM 898 O LEU 172-9.754 7.548 0.171 1.00 0.00 ATOM 899 N PRO 173-9.986 8.434 2.221 1.00 0.00 ATOM 900 CD PRO 173-9.570 9.290 3.350 1.00 0.00 ATOM 901 CA PRO 173-11.253 7.749 2.487 1.00 0.00 ATOM 902 HA PRO 173-11.151 6.678 2.372 1.00 0.00 ATOM 903 CB PRO 173-11.550 8.084 3.952 1.00 0.00 ATOM 904 1HB PRO 173-11.213 7.275 4.583 1.00 0.00 ATOM 905 2HB PRO 173-12.613 8.228 4.080 1.00 0.00 ATOM 906 QB PRO 173-11.913 7.751 4.331 1.00 0.00 ATOM 907 CG PRO 173-10.792 9.339 4.224 1.00 0.00 ATOM 908 1HG PRO 173-10.506 9.376 5.266 1.00 0.00 ATOM 909 2HG PRO 173-11.400 10.196 3.972 1.00 0.00 ATOM 910 QG PRO 173-10.953 9.786 4.619 1.00 0.00 ATOM 911 1HD PRO 173-8.742 8.846 3.884 1.00 0. 00 ATOM 912 2HD PRO 173-9.311 10.281 3.007 1.00 0.00 ATOM 913 QD PRO 173-9.026 9.563 3.445 1.00 0.00 ATOM 914 C PRO 173-12.381 8.246 1.583 1.00 0.00 ATOM 915 O PRO 173-12.331 9.362 1.055 1.00 0.00 ATOM 916 N CYS 174-13.396 7.417 1.411 1.00 0.00 ATOM 917 H CYS 174-13.379 6.542 1.858 1.00 0.00 ATOM 918 CA CYS 174-14.540 7.772 0.581 1.00 0.00 ATOM 919 HA CYS 174-14. 559 8.848 0.492 1.00 0.00 ATOM 920 CB CYS 174-14.426 7.159-0.812 1.00 0.00 ATOM 921 1HB CYS 174-13.855 7.824-1.442 1.00 0.00 ATOM 922 2HB CYS 174-15.417 7.045-1.226 1.00 0.00 ATOM 923 QB CYS 174-14.636 7.434-1.334 1.00 0.00 ATOM 924 SG CYS 174-13.621 5.527-0.856 1.00 0.00 ATOM 925 C CYS 174-15.831 7.316 1.238 1.00 0.00 ATOM 926 O CYS 174-16.896 7.879 0.998 1.00 0.00 ATOM 927 N GLY 175-15.723 6.299 2.076 1.00 0.00 ATOM 928 H GLY 175-14.842 5.899 2.236 1.00 0.00 ATOM 929 CA GLY 175-16.877 5.785 2.776 1.00 0.00 ATOM 930 1HA GLY 175-17.146 4.825 2.365 1.00 0.00 ATOM 931 2HA GLY 175-17.703 6.472 2.651 1.00 0.00 ATOM 932 QA GLY 175-17.424 5.648 2.508 1.00 0.00 ATOM 933 C GLY 175-16.581 5.628 4.246 1.00 0.00 ATOM 934 O GLY 175-15.550 6.107 4.714 1.00 0.00

ATOM 935 N ILE 176-17. 463 4.952 4.973 1.00 0.00 ATOM 936 H ILE 176-18.261 4.586 4.542 1.00 0.00 ATOM 937 CA ILE 176-17.257 4.731 6.400 1.00 0.00 ATOM 938 HA ILE 176-17.179 5.695 6.884 1.00 0.00 ATOM 939 CB ILE 176-18.430 3.949 7.035 1.00 0.00 ATOM 940 HB ILE 176-18. 271 2.898 6.848 1.00 0.00 ATOM 941 QG2 ILE 176-18.464 4.209 8.899 1.00 0.00 ATOM 942 CG2 ILE 176-18. 457 4.159 8.543 1.00 0.00 ATOM 943 1HG2 ILE 176-17.453 4.329 8.901 1.00 0.00 ATOM 944 2HG2 ILE 176-18.867 3.282 9.021 1.00 0.00 ATOM 945 3HG2 ILE 176-19.073 5.016 8.775 1.00 0.00 ATOM 946 CG1 ILE 176-19.766 4.372 6.412 1.00 0.00 ATOM 947 1HG1 ILE 176-20.522 3.646 6.674 1.00 0.00 ATOM 948 2HG1 ILE 176-19.663 4.405 5.339 1.00 0.00 ATOM 949 QG1 ILE 176-20.092 4.025 6.006 1.00 0.00 ATOM 950 QD1 ILE 176-20.365 6.055 6.982 1.00 0.00 ATOM 951 CD1 ILE 176-20.251 5.732 6.871 1.00 0.00 ATOM 952 1HD1 ILE 176-21. 211 5.943 6.426 1.00 0.00 ATOM 953 2HD1 ILE 176-19.540 6.488 6.572 1.00 0.00 ATOM 954 3HD1 ILE 176-20.345 5.734 7.948 1.00 0.00 ATOM 955 C ILE 176-15.957 3.958 6.617 1.00 0.00 ATOM 956 O ILE 176-15.091 4.377 7.382 1.00 0.00 ATOM 957 N ASP 177-15.825 2.845 5.902 1.00 0.00 ATOM 958 H ASP 177-16.544 2.586 5.293 1.00 0.00 ATOM 959 CA ASP 177-14.626 2.018 5.968 1.00 0.00 ATOM 960 HA ASP 177-13.864 2.579 6.490 1.00 0.00 ATOM 961 CB ASP 177-14. 891 0.710 6.723 1.00 0.00 ATOM 962 1HB ASP 177-15.443 0.038 6.084 1.00 0.00 ATOM 963 2HB ASP 177-15.474 0.922 7.606 1.00 0.00 ATOM 964 QB ASP 177-15.458 0.480 6.845 1.00 0.00 ATOM 965 CG ASP 177-13.608 0.015 7.154 1.00 0.00 ATOM 966 OD1 ASP 177-13.701-1.048 7.799 1.00 0.00 ATOM 967 OD2 ASP 177-12.511 0.525 6.836 1.00 0.00 ATOM 968 C ASP 177-14.134 1.718 4.554 1.00 0.00 ATOM 969 O ASP 177-13.871 0.570 4.189 1.00 0.00 ATOM 970 N LYS+ 178-14.013 2.765 3.752 1.00 0.00 ATOM 971 H LYS+ 178-14.233 3.657 4.097 1.00 0.00 ATOM 972 CA LYS+ 178-13.541 2.629 2.381 1.00 0.00 ATOM 973 HA LYS+ 178-13.042 1.673 2.299 1.00 0.00 ATOM 974 CB LYS+ 178-14. 687 2.689 1.369 1.00 0.00 ATOM 975 1HB LYS+ 178-14.290 2.474 0.387 1.00 0.00 ATOM 976 2HB LYS+ 178-15.090 3.687 1.368 1.00 0.00 ATOM 977 QB LYS+ 178-14.690 3.080 0.877 1.00 0.00 ATOM 978 CG LYS+ 178-15.818 1.706 1.653 1.00 0.00 ATOM 979 1HG LYS+ 178-16.676 2.254 2.015 1.00 0.00 ATOM 980 2HG LYS+ 178-15.490 1.009 2.412 1.00 0.00 ATOM 981 QG LYS+ 178-16. 083 1.631 2.213 1.00 0.00 ATOM 982 CD LYS+ 178-16.216 0.926 0.407 1.00 0 00 ATOM 983 1HD LYS+ 178-15.655 1.304-0.436 1.00 0.00 ATOM 984 2HD LYS+ 178-17.272 1.068 0.230 1.00 0.00 ATOM 985 QD LYS+ 178-16.463 1.186-0.103 1.00 0.00 ATOM 986 CE LYS+ 178-15.938-0.567 0.557 1.00 0.00 ATOM 987 1HE LYS+ 178-16.712-1.005 1.172 1.00 0.00 ATOM 988 2HE LYS+ 178-14.980-0.696 1.041 1.00 0.00 ATOM 989 QE LYS+ 178-15.846-0.851 1.106 1.00 0.00 ATOM 990 NZ LYS+ 178-15.911-1.264-0.761 1.00 0.00 ATOM 991 1HZ LYS+ 178-16.870-1.531-1.053 1.00 0.00 ATOM 992 2HZ LYS+ 178-15.326-2.136-0.704 1.00 0.00 ATOM 993 3HZ LYS+ 178-15.496-0.645-1.493 1.00 0.00 ATOM 994 QZ LYS+ 178-15.897-1.438-1.084 1.00 0.00 ATOM 995 C LYS+ 178-12.529 3.712 2.093 1.00 0.00 ATOM 996 O LYS+ 178-12. 727 4.875 2.450 1.00 0.00 ATOM 997 N PHE 179-11.439 3.319 1.468 1.00 0.00 ATOM 998 H PHE 179-11.347 2.375 1.222 1.00 0.00 ATOM 999 CA PHE 179-10.366 4.239 1.157 1.00 0.00 ATOM 1000 HA PHE 179-10.693 5.235 1.411 1.00 0.00 ATOM 1001 CB PHE 179-9.123 3.897 1.979 1.00 0.00 ATOM 1002 1HB PHE 179-8.397 4.668 1.831 1.00 0.00 ATOM 1003 2HB PHE 179-8.710 2.966 1.624 1.00 0.00 ATOM 1004 QB PHE 179-8.553 3.817 1.727 1.00 0.00 ATOM 1005 QD PHE 179-9.405 3.754 3.623 1.00 0. 00 ATOM 1006 QE PHE 179-9.829 3.558 6.038 1.00 0.00

ATOM 1007 QR PHE 179-9.702 3.617 5.314 1.00 0.00 ATOM 1008 CG PHE 179-9.375 3.769 3.458 1.00 0.00 ATOM 1009 CD1 PHE 179-9.097 4.823 4.312 1.00 0.00 ATOM 1010 1HD PHE 179-8.691 5.739 3.908 1.00 0.00 ATOM 1011 CE1 PHE 179-9.333 4.715 5.669 1.00 0.00 ATOM 1012 1HE PHE 179-9.111 5.545 6.324 1.00 0.00 ATOM 1013 CZ PHE 179-9.854 3.546 6.188 1.00 0.00 ATOM 1014 HZ PHE 179-10.042 3.460 7.249 1.00 0.00 ATOM 1015 CE2 PHE 179-10.135 2.486 5.349 1.00 0.00 ATOM 1016 2HE PHE 179-10. 547 1.571 5.753 1.00 0.00 ATOM 1017 CD2 PHE 179-9.897 2.599 3.993 1.00 0.00 ATOM 1018 2HD PHE 179-10.119 1.769 3.338 1.00 0.00 ATOM 1019 C PHE 179-10. 014 4.192-0.313 1.00 0.00 ATOM 1020 O PHE 179-10.643 3.475-1.090 1.00 0.00 ATOM 1021 N ARG+ 180-8.990 4.948-0.677 1.00 0.00 ATOM 1022 H ARG+ 180-8.530 5.484 0.006 1.00 0.00 ATOM 1023 CA ARG+ 180-8.518 4.999-2.051 1.00 0.00 ATOM 1024 HA ARG+ 180-8.906 4.136-2.573 1.00 0.00 ATOM 1025 CB ARG+ 180-9.012 6. 273-2.746 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.643 6.269-3.762 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.603 7.128-2.236 1.00 0.00 ATOM 1028 QB ARG+ 180-8.623 6.698-2.999 1.00 0.00 ATOM 1029 CG ARG+ 180-10.525 6.420-2.791 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.872 6.792-1.838 1.00 0.00 ATOM 1031 2HG ARG+ 180-10. 964 5.451-2.986 1.00 0.00 ATOM 1032 QG ARG+ 180-10. 918 6.121-2.412 1.00 0.00 ATOM 1033 CD ARG+ 180-10.948 7.385-3.890 1.00 0.00 ATOM 1034 1HD ARG+ 180-11.229 6.806-4.761 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.106 8.012-4.141 1.00 0.00 ATOM 1036 QD ARG+ 180-10.667 7.409-4.451 1.00 0.00 ATOM 1037 NE ARG+ 180-12.075 8.242-3.509 1.00 0.00 ATOM 1038 HE ARG+ 180-12.908 8.133-4.021 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.025 9.173-2.552 1.00 0.00 ATOM 1040 NH1 ARG+ 180-10.933 9.314-1.814 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-10.141 8.721-1.974 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-10.899 10.002-1.088 1.00 0.00 ATOM 1043 QH1 ARG+ 180-10.520 9.361-1.531 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.076 9.953-2.328 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-13. 907 9.848-2.877 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.042 10.649-1.607 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13.474 10.248-2.242 1.00 0.00 ATOM 1048 C ARG+ 180-6.991 4.970-2.103 1.00 0.00 ATOM 1049 O ARG+ 180-6. 405 4.665-3.134 1.00 0.00 ATOM 1050 N GLY 181-6. 344 5.308-0.998 1.00 0.00 ATOM 1051 H GLY 181-6.850 5.552-0.192 1.00 0.00 ATOM 1052 CA GLY 181-4.892 5.335-0.982 1.00 0.00 ATOM 1053 1HA GLY 181-4.567 6.279-0.568 1.00 0.00 ATOM 1054 2HA GLY 181-4.535 5.262-1.999 1.00 0. 00 ATOM 1055 QA GLY 181-4. 551 5.770-1.284 1.00 0.00 ATOM 1056 C GLY 181-4.280 4.215-0.176 1.00 0.00 ATOM 1057 O GLY 181-4.910 3.679 0.733 1.00 0.00 ATOM 1058 N VAL 182-3.041 3.867-0.514 1.00 0.00 ATOM 1059 H VAL 182-2.601 4.344-1.246 1.00 0.00 ATOM 1060 CA VAL 182-2.311 2.808 0.172 1.00 0.00 ATOM 1061 HA VAL 182-2.729 2.702 1.167 1.00 0.00 ATOM 1062 CB VAL 182-2.421 1.445-0.563 1.00 0.00 ATOM 1063 HB VAL 182-1.567 1.352-1.221 1.00 0.00 ATOM 1064 QG1 VAL 182-2.360 0. 023 0.663 1.00 0. 00 ATOM 1065 QG2 VAL 182-3.980 1.334-1.612 1.00 0.00 ATOM 1066 CG1 VAL 182-2.372 0.296 0.429 1.00 0.00 ATOM 1067 1HG1 VAL 182-2.337 0.689 1.435 1.00 0.00 ATOM 1068 2HG1 VAL 182-1.491-0.302 0.244 1.00 0.00 ATOM 1069 3HG1 VAL 182-3.253-0.317 0.312 1.00 0.00 ATOM 1070 CG2 VAL 182-3.682 1.355-1.411 1.00 0.00 ATOM 1071 1HG2 VAL 182-4.504 1.818-0.884 1.00 0.00 ATOM 1072 2HG2 VAL 182-3.915 0.318-1.602 1.00 0.00 ATOM 1073 3HG2 VAL 182-3.523 1.867-2.349 1.00 0.00 ATOM 1074 QQG VAL 182-3.170 0.679-0.474 1.00 0.00 ATOM 1075 C VAL 182-0.827 3.177 0.293 1.00 0.00 ATOM 1076 O VAL 182-0.186 3.531-0.696 1.00 0.00 ATOM 1077 N GLU 183-0.299 3.086 1.507 1.00 0.00 ATOM 1078 H GLU 183-0.871 2.794 2.247 1.00 0.00

ATOM 1079 CA GLU 183 1.103 3.398 1.792 1.00 0.00 ATOM 1080 HA GLU 183 1.611 3.616 0.857 1.00 0.00 ATOM 1081 CB GLU 183 1.190 4.614 2.721 1.00 0.00 ATOM 1082 1HB GLU 183 1.662 5.426 2.188 1.00 0.00 ATOM 1083 2HB GLU 183 1.799 4.355 3.575 1.00 0.00 ATOM 1084 QB GLU 183 1.731 4.890 2.881 1.00 0.00 ATOM 1085 CG GLU 183-0.159 5.102 3.234 1.00 0.00 ATOM 1086 1HG GLU 183-0. 819 4.253 3.336 1.00 0.00 ATOM 1087 2HG GLU 183-0.573 5.795 2.516 1.00 0.00 ATOM 1088 QG GLU 183-0.696 5.024 2.926 1.00 0.00 ATOM 1089 CD GLU 183-0.060 5.801 4.573 1.00 0.00 ATOM 1090 OE1 GLU 183-0.693 5.326 5.535 1.00 0.00 ATOM 1091 OE2 GLU 183 0.644 6.830 4.657 1.00 0.00 ATOM 1092 C GLU 183 1.756 2.201 2.477 1.00 0. 00 ATOM 1093 O GLU 183 1.701 2.079 3.693 1.00 0.00 ATOM 1094 N PHE 184 2.335 1.295 1.711 1.00 0.00 ATOM 1095 H PHE 184 2.335 1.412 0.740 1.00 0.00 ATOM 1096 CA PHE 184 2.929 0.099 2.301 1.00 0.00 ATOM 1097 HA PHE 184 2.745 0.150 3.362 1.00 0.00 ATOM 1098 CB PHE 184 2.257-1.169 1.759 1.00 0.00 ATOM 1099 1HB PHE 184 1.335-1.337 2.297 1.00 0.00 ATOM 1100 2HB PHE 184 2.915-2.010 1.935 1.00 0.00 ATOM 1101 QB PHE 184 2.125-1.674 2.116 1.00 0. 00 ATOM 1102 QD PHE 184 1.902-1.142 0.111 1.00 0.00 ATOM 1103 QE PHE 184 1.355-1.162-2.285 1.00 0.00 ATOM 1104 QR PHE 184 1.517-1.159-1.566 1.00 0.00 ATOM 1105 CG PHE 184 1.939-1.144 0.280 1.00 0.00 ATOM 1106 CD1 PHE 184 2.599-1.992-0.592 1.00 0.00 ATOM 1107 1HD PHE 184 3.363-2.653-0.211 1.00 0.00 ATOM 1108 CE1 PHE 184 2.291-2.008-1.938 1.00 0.00 ATOM 1109 1HE PHE 184 2.816-2.677-2.604 1.00 0.00 ATOM 1110 CZ PHE 184 1.319-1.166-2.432 1.00 0.00 ATOM 1111 HZ PHE 184 1.071-1.185-3.482 1.00 0.00 ATOM 1112 CE2 PHE 184 0.655-0.309-1.580 1.00 0.00 ATOM 1113 2HE PHE 184-0.107 0.353-1.965 1.00 0.00 ATOM 1114 CD2 PHE 184 0.961-0.303-0.232 1.00 0.00 ATOM 1115 2HD PHE 184 0.440 0.370 0.433 1.00 0.00 ATOM 1116 C PHE 184 4.428-0.002 2.086 1.00 0.00 ATOM 1117 O PHE 184 4.931 0.209 0.990 1.00 0.00 ATOM 1118 N VAL 185 5.128-0.367 3.148 1.00 0.00 ATOM 1119 H VAL 185 4.657-0.544 3.992 1.00 0. 00 ATOM 1120 CA VAL 185 6.566-0.540 3.100 1.00 0.00 ATOM 1121 HA VAL 185 6.915-0.165 2.148 1.00 0.00 ATOM 1122 CB VAL 185 7.270 0.249 4.231 1.00 0.00 ATOM 1123 HB VAL 185 7.332-0.385 5.108 1.00 0.00 ATOM 1124 QG1 VAL 185 9.010 0.735 3.727 1.00 0.00 ATOM 1125 QG2 VAL 185 6.286 1.787 4. 687 1.00 0.00 ATOM 1126 CG1 VAL 185 8.677 0.641 3.822 1.00 0.00 ATOM 1127 1HG1 VAL 185 8.903 0.219 2.856 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.378 0.270 4.555 1.00 0.00 ATOM 1129 3HG1 VAL 185 8.747 1.718 3.771 1.00 0.00 ATOM 1130 CG2 VAL 185 6.474 1.494 4.598 1.00 0.00 ATOM 1131 1HG2 VAL 185 5.484 1.429 4.171 1.00 0.00 ATOM 1132 2HG2 VAL 185 6.976 2.369 4.215 1.00 0. 00 ATOM 1133 3HG2 VAL 185 6.397 1.565 5.675 1.00 0.00 ATOM 1134 QQG VAL 185 7.648 1.261 4.207 1.00 0.00 ATOM 1135 C VAL 185 6.902-2.029 3.198 1.00 0.00 ATOM 1136 O VAL 185 6.773-2.641 4.256 1.00 0. 00 ATOM 1137 N CYS 186 7.306-2.615 2.080 1.00 0.00 ATOM 1138 H CYS 186 7.372-2.081 1.256 1.00 0.00 ATOM 1139 CA CYS 186 7.637-4.033 2.038 1.00 0.00 ATOM 1140 HA CYS 186 7.363-4.461 2.992 1.00 0.00 ATOM 1141 CB CYS 186 6.838-4.737 0.931 1.00 0.00 ATOM 1142 1HB CYS 186 5.809-4.827 1.248 1.00 0.00 ATOM 1143 2HB CYS 186 7.245-5.724 0.782 1.00 0.00 ATOM 1144 QB CYS 186 6.527-5.276 1.015 1.00 0.00 ATOM 1145 SG CYS 186 6.848-3.897-0.685 1.00 0.00 ATOM 1146 C CYS 186 9.135-4.232 1.827 1.00 0.00 ATOM 1147 O CYS 186 9.722-3.629 0.943 1.00 0.00 ATOM 1148 N CYS 187 9.757-5.080 2.634 1.00 0.00 ATOM 1149 H CYS 187 9.245-5.549 3.328 1.00 0.00 ATOM 1150 CA CYS 187 11. 198-5. 322 2.507 1.00 0.00

ATOM 1151 HA CYS 187 11.641-4.433 2.082 1.00 0.00 ATOM 1152 CB CYS 187 11.838-5.585 3.874 1.00 0.00 ATOM 1153 1HB CYS 187 1. 636-6. 305 3.754 1.00 0.00 ATOM 1154 2HB CYS 187 11.093-5.994 4.539 1.00 0.00 ATOM 1155 QB CYS 187 11.865-6.150 4.146 1.00 0.00 ATOM 1156 SG CYS 187 12.540-4.107 4.676 1.00 0.00 ATOM 1157 C CYS 187 11.489-6.494 1.591 1.00 0. 00 ATOM 1158 O CYS 187 10.720-7.449 1.538 1.00 0.00 ATOM 1159 N PRO 188 12.607-6.422 0.846 1.00 0.00 ATOM 1160 CD PRO 188 13.560-5.295 0.844 1.00 0.00 ATOM 1161 CA PRO 188 13.009-7.479-0.086 1.00 0.00 ATOM 1162 HA PRO 188 12.244-7.657-0.830 1.00 0.00 ATOM 1163 CB PRO 188 14.262-6.918-0.767 1.00 0.00 ATOM 1164 1HB PRO 188 13.999-6.511-1.732 1.00 0.00 ATOM 1165 2HB PRO 188 14.987-7.710-0.892 1.00 0.00 ATOM 1166 QB PRO 188 14.493-7.111-1.312 1.00 0.00 ATOM 1167 CG PRO 188 14.767-5.858 0.151 1.00 0. 00 ATOM 1168 1HG PRO 188 15.266-5.086-0.418 1.00 0.00 ATOM 1169 2HG PRO 188 15.445-6.291 0.871 1.00 0.00 ATOM 1170 QG PRO 188 15.356-5.689 0.226 1.00 0.00 ATOM 1171 1HD PRO 188 13.163-4.456 0.290 1.00 0.00 ATOM 1172 2HD PRO 188 13.809-4.997 1.852 1.00 0.00 ATOM 1173 QD PRO 188 13.486-4.727 1.071 1.00 0.00 ATOM 1174 C PRO 188 13.331-8.794 0.619 1.00 0.00 ATOM 1175 O PRO 188 14.186-8.841 1.512 1.00 0.00 ATOM 1176 N LEU 189 12.642-9.845 0.197 1.00 0.00 ATOM 1177 H LEU 189 11.985-9.721-0.521 1.00 0.00 ATOM 1178 CA LEU 189 12.828-11.177 0.744 1.00 0.00 ATOM 1179 HA LEU 189 13.637-11.139 1.457 1.00 0.00 ATOM 1180 CB LEU 189 11.553-11.651 1.445 1.00 0.00 ATOM 1181 1HB LEU 189 10.806-11.842 0.689 1.00 0.00 ATOM 1182 2HB LEU 189 11.200-10.855 2.083 1.00 0.00 ATOM 1183 QB LEU 189 11.003-11.349 1.386 1.00 0.00 ATOM 1184 CG LEU 189 11.707-12.916 2.291 1.00 0.00 ATOM 1185 HG LEU 189 12.466-13.546 1.846 1.00 0.00 ATOM 1186 QD1 LEU 189 12.257-12.486 4.035 1.00 0.00 ATOM 1187 QD2 LEU 189 10.096-13.881 2.328 1.00 0.00 ATOM 1188 CD1 LEU 189 12.152-12.568 3.702 1.00 0.00 ATOM 1189 1HD1 LEU 189 13.156-12.173 3.675 1.00 0.00 ATOM 1190 2HD1 LEU 189 12.130-13.456 4.315 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.484-11.828 4.116 1.00 0.00 ATOM 1192 CD2 LEU 189 10.403-13.696 2.321 1.00 0.00 ATOM 1193 1HD2 LEU 189 10.512-14.552 2.970 1.00 0.00 ATOM 1194 2HD2 LEU 189 10.161-14.029 1.323 1.00 0.00 ATOM 1195 3HD2 LEU 189 9.613-13.061 2.691 1.00 0.00 ATOM 1196 QQD LEU 189 11.176-13.183 3.181 1.00 0.00 ATOM 1197 C LEU 189 13.195-12.144-0.378 1.00 0.00 ATOM 1198 OT1 LEU 189 12.830-11.859-1.540 1.00 0. 00 ATOM 1199 OT2 LEU 189 13.843-13.170-0.090 1.00 0.00 TER ENDMDL MODEL 12 ATOM 1 N SER 124 12.765 15.644 3.969 1.00 0.00 ATOM 2 CA SER 124 12.645 14.207 4.338 1.00 0.00 ATOM 3 HA SER 124 13.471 13.662 3.904 1.00 0.00 ATOM 4 CB SER 124 12.707 14.106 5.862 1.00 0.00 ATOM 5 1HB SER 124 13.379 13.306 6.142 1.00 0.00 ATOM 6 2HB SER 124 11.718 13.897 6.249 1.00 0.00 ATOM 7 QB SER 124 12.549 13.602 6.196 1.00 0.00 ATOM 8 OG SER 124 13.177 15.323 6.425 1.00 0.00 ATOM 9 HG SER 124 13.182 15.252 7.389 1.00 0.00 ATOM 10 C SER 124 11.336 13.638 3.819 1.00 0.00 ATOM 11 O SER 124 10.748 12.735 4.413 1.00 0.00 ATOM 12 1HT SER 124 12.917 16.214 4.825 1.00 0.00 ATOM 13 2HT SER 124 11. 891 15.970 3.499 1.00 0.00 ATOM 14 3HT SER 124 13.565 15.786 3.322 1.00 0.00 ATOM 15 N ASP 125 10.889 14.201 2.714 1.00 0.00 ATOM 16 H ASP 125 11.410 14.929 2.307 1.00 0.00 ATOM 17 CA ASP 125 9.647 13.820 2.072 1.00 0.00 ATOM 18 HA ASP 125 8.932 13.567 2.841 1.00 0.00 ATOM 19 CB ASP 125 9.123 15.015 1.271 1.00 0.00 ATOM 20 1HB ASP 125 8.048 15.061 1.364 1.00 0.00

ATOM 21 2HB ASP 125 9.386 14.888 0.232 1.00 0.00 ATOM 22 QB ASP 125 8.717 14.975 0.798 1.00 0.00 ATOM 23 CG ASP 125 9.704 16.331 1.760 1.00 0.00 ATOM 24 OD1 ASP 125 10.937 16.534 1.618 1.00 0.00 ATOM 25 OD2 ASP 125 8.943 17.144 2.313 1.00 0.00 ATOM 26 C ASP 125 9.857 12.614 1.166 1.00 0.00 ATOM 27 O ASP 125 9.752 12.708-0.057 1.00 0.00 ATOM 28 N ALA 126 10.160 11.478 1.775 1.00 0.00 ATOM 29 H ALA 126 10.230 11.465 2.754 1.00 0.00 ATOM 30 CA ALA 126 10.386 10.252 1.028 1.00 0.00 ATOM 31 HA ALA 126 10.824 10.517 0.077 1.00 0. 00 ATOM 32 QB ALA 126 11.591 9.133 1.944 1.00 0.00 ATOM 33 CB ALA 126 11.362 9.347 1.768 1.00 0.00 ATOM 34 1HB ALA 126 12.058 8.917 1.064 1.00 0.00 ATOM 35 2HB ALA 126 10.813 8.557 2.261 1.00 0.00 ATOM 36 3HB ALA 126 11.903 9.923 2.505 1.00 0.00 ATOM 37 C ALA 126 9.073 9.525 0.782 1.00 0.00 ATOM 38 O ALA 126 8.628 8.726 1.605 1.00 0.00 ATOM 39 N LEU 127 8.458 9.813-0.355 1.00 0.00 ATOM 40 H LEU 127 8.864 10.462-0.964 1.00 0.00 ATOM 41 CA LEU 127 7.193 9.194-0.722 1.00 0.00 ATOM 42 HA LEU 127 6.697 8.882 0.183 1.00 0.00 ATOM 43 CB LEU 127 6.314 10.210-1.458 1.00 0.00 ATOM 44 1HB LEU 127 6.533 10.138-2.513 1.00 0.00 ATOM 45 2HB LEU 127 6.584 11.199-1.119 1.00 0.00 ATOM 46 QB LEU 127 6.559 10.669-1.816 1.00 0.00 ATOM 47 CG LEU 127 4.805 10.031-1.271 1.00 0.00 ATOM 48 HG LEU 127 4.608 9.029-0.916 1.00 0. 00 ATOM 49 QD1 LEU 127 4.149 11.240 0.010 1.00 0.00 ATOM 50 QD2 LEU 127 3.904 10.259-2.904 1.00 0.00 ATOM 51 CD1 LEU 127 4.276 11.008-0.236 1.00 0.00 ATOM 52 1HD1 LEU 127 4.877 11.905-0.245 1.00 0.00 ATOM 53 2HD1 LEU 127 4.319 10.554 0.744 1.00 0.00 ATOM 54 3HD1 LEU 127 3.252 11.260-0.471 1.00 0.00 ATOM 55 CD2 LEU 127 4.077 10.215-2.593 1.00 0.00 ATOM 56 1HD2 LEU 127 3.026 10.378-2.403 1.00 0.00 ATOM 57 2HD2 LEU 127 4.201 9.330-3.198 1.00 0.00 ATOM 58 3HD2 LEU 127 4.486 11.069-3.113 1.00 0.00 ATOM 59 QQD LEU 127 4.027 10.750-1.447 1.00 0.00 ATOM 60 C LEU 127 7. 433 7.975-1.608 1.00 0.00 ATOM 61 O LEU 127 6.509 7.446-2.225 1.00 0.00 ATOM 62 N LEU 128 8.682 7.537-1.671 1.00 0.00 ATOM 63 H LEU 128 9.374 7.998-1.159 1.00 0.00 ATOM 64 CA LEU 128 9.045 6.388-2.482 1.00 0. 00 ATOM 65 HA LEU 128 8.142 5.841-2.704 1.00 0.00 ATOM 66 CB LEU 128 9.691 6.864-3.796 1.00 0.00 ATOM 67 1HB LEU 128 10.760 6.908-3.644 1.00 0.00 ATOM 68 2HB LEU 128 9.338 7.864-3.997 1.00 0. 00 ATOM 69 QB LEU 128 10. 049 7.386-3.820 1.00 0.00 ATOM 70 CG LEU 128 9.424 6.008-5.049 1.00 0.00 ATOM 71 HG LEU 128 8.956 6. 632-5.801 1.00 0.00 ATOM 72 QD1 LEU 128 11.035 5.360-5.771 1.00 0.00 ATOM 73 QD2 LEU 128 8.245 4.590-4.681 1.00 0.00 ATOM 74 CD1 LEU 128 10.726 5.484-5.632 1.00 0.00 ATOM 75 1HD1 LEU 128 10.667 4.411-5.740 1.00 0.00 ATOM 76 2HD1 LEU 128 11.544 5.735-4.973 1.00 0.00 ATOM 77 3HD1 LEU 128 10.893 5. 934-6.600 1.00 0.00 ATOM 78 CD2 LEU 128 8.472 4.861-4.752 1.00 0.00 ATOM 79 1HD2 LEU 128 8.826 4.310-3.893 1.00 0.00 ATOM 80 2HD2 LEU 128 8.422 4.203-5.606 1.00 0. 00 ATOM 81 3HD2 LEU 128 7.487 5.256-4.544 1.00 0.00 ATOM 82 QQD LEU 128 9.640 4.975-5.226 1.00 0.00 ATOM 83 C LEU 128 9.995 5.486-1.687 1.00 0.00 ATOM 84 O LEU 128 10.061 5.594-0. 463 1. 00 o. oo ATOM 85 N VAL 129 10.708 4.600-2.383 1.00 0.00 ATOM 86 H VAL 129 10.596 4.569-3.354 1.00 0.00 ATOM 87 CA VAL 129 11.647 3.664-1.752 1.00 0.00 ATOM 88 HA VAL 129 11.073 2.947-1.185 1.00 0.00 ATOM 89 CB VAL 129 12.454 2.900-2. 826 1. 00 0. 00 ATOM 90 HB VAL 129 13. 090 3.610-3.336 1.00 0.00 ATOM 91 QG1 VAL 129 13.557 1.589-2-050 1.00 0. 00 ATOM 92 QG2 VAL 129 11.305 2.125-4.097 1.00 0. 00

ATOM 93 CG1 VAL 129 13.345 1.839-2.199 1.00 0.00 ATOM 94 1HG1 VAL 129 12.787 1.293-1.451 1.00 0.00 ATOM 95 2HG1 VAL 129 14.198 2.315-1.735 1.00 0.00 ATOM 96 3HG1 VAL 129 13.687 1.158-2.964 1.00 0.00 ATOM 97 CG2 VAL 129 11.524 2.273-3.854 1.00 0.00 ATOM 98 1HG2 VAL 129 11.774 2.645-4.837 1.00 0.00 ATOM 99 2HG2 VAL 129 10.501 2.530-3.620 1.00 0.00 ATOM 100 3HG2 VAL 129 11.641 1.200-3.836 1.00 0.00 ATOM 101 QQG VAL 129 12.431 1.857-3.074 1.00 0.00 ATOM 102 C VAL 129 12.618 4.378-0.806 1.00 0.00 ATOM 103 O VAL 129 13.412 5.213-1.234 1.00 0.00 ATOM 104 N PRO 130 12.544 4.063 0.503 1.00 0.00 ATOM 105 CD PRO 130 11.610 3.111 1.099 1.00 0. 00 ATOM 106 CA PRO 130 13.391 4.668 1.525 1.00 0.00 ATOM 107 HA PRO 130 13.577 5.703 1.315 1.00 0.00 ATOM 108 CB PRO 130 12.539 4.555 2.805 1.00 0.00 ATOM 109 1HB PRO 130 12.242 5.545 3.122 1.00 0.00 ATOM 110 2HB PRO 130 13.124 4.090 3.584 1. 00 0.00 ATOM 111 QB PRO 130 12. 683 4.818 3.353 1.00 0.00 ATOM 112 CG PRO 130 11.341 3.718 2.449 1.00 0.00 ATOM 113 1HG PRO 130 10.460 4.345 2.407 1.00 0.00 ATOM 114 2HG PRO 130 11.207 2.940 3.186 1.00 0.00 ATOM 115 QG PRO 130 10. 834 3.643 2. 797 1.00 0.00 ATOM 116 1HD PRO 130 10.700 3.052 0. 522 1.00 0.00 ATOM 117 2HD PRO 130 12.063 2.135 1.201 1.00 0.00 ATOM 118 QD PRO 130 11.382 2.594 0.862 1.00 0.00 ATOM 119 C PRO 130 14.731 3.955 1.701 1.00 0.00 ATOM 120 O PRO 130 15.704 4.255 1.015 1.00 0.00 ATOM 121 N ASP 131 14.767 3.033 2.651 1.00 0.00 ATOM 122 H ASP 131 13.958 2.873 3, 167 1.00 0.00 ATOM 123 CA ASP 131 15.980 2.280 2.970 1.00 0.00 ATOM 124 HA ASP 131 16.827 2.936 2. 828 1.00 0.00 ATOM 125 CB ASP 131 15.928 1. 849 4.442 1.00 0. 00 ATOM 126 1HB ASP 131 15.205 1.055 4.551 1.00 0.00 ATOM 127 2HB ASP 131 15.620 2.691 5. 043 1.00 0.00 ATOM 128 QB ASP 131 15.413 1.873 4.797 1.00 0.00 ATOM 129 CG ASP 131 17.259 1.358 4.966 1.00 0.00 ATOM 130 OD1 ASP 131 17.271 0.698 6.022 1.00 0.00 ATOM 131 OD2 ASP 131 18.292 1.607 4.318 1.00 0.00 ATOM 132 C ASP 131 16.150 1.056 2.063 1.00 0.00 ATOM 133 O ASP 131 16.579 1.172 0.918 1.00 0.00 ATOM 134 N LYS+ 132 15. 817-0. 123 2.584 1.00 0.00 ATOM 135 H LYS+ 132 15. 488-0. 160 3.505 1.00 0.00 ATOM 136 CA LYS+ 132 15.946-1.361 1.816 1.00 0.00 ATOM 137 HA LYS+ 132 16.509-1.136 0.922 1.00 0.00 ATOM 138 CB LYS+ 132 16. 696-2. 427 2.625 1.00 0. 00 ATOM 139 1HB LYS+ 132 17. 062-3. 182 1.943. 1.00 0.00 ATOM 140 2HB LYS+ 132 16.005-2.888 3.315 1.00 0.00 ATOM 141 QB LYS+ 132 16. 534-3. 035 2.629 1.00 0.00 ATOM 142 CG LYS+ 132 17.878-1.889 3.421 1.00 0.00 ATOM 143 1HG LYS+ 132 17.641-0. 893 3.770 1.00 0.00 ATOM 144 2HG LYS+ 132 18.744-1.849 2.775 1.00 0.00 ATOM 145 QG LYS+ 132 18. 193-1. 371 3.273 1.00 0. 00 ATOM 146 CD LYS+ 132 18. 197-2. 774 4.621 1.00 0.00 ATOM 147 1HD LYS+ 132 18.880-3.553 4.311 1.00 0.00 ATOM 148 2HD LYS+ 132 17.280-3.221 4.979 1.00 0.00 ATOM 149 QD LYS+ 132 18.080-3.387 4.645 1.00 0.00 ATOM 150 CE LYS+ 132 18. 833-1. 982 5.759 1.00 0.00 ATOM 151 1HE LYS+ 132 19. 596-2. 590 6.222 1.00 0.00 ATOM 152 2HE LYS+ 132 18. 068-1. 750 6.488 1.00 0.00 ATOM 153 QE LYS+ 132 18.832-2.170 6.355 1.00 0. 00 ATOM 154 NZ LYS+ 132 19.445-0.709 5.285 1.00 0.00 ATOM 155 1HZ LYS+ 132 20.344-0.534 5.770 1.00 0.00 ATOM 156 2HZ LYS+ 132 18.795 0.095 5.483 1.00 0.00 ATOM 157 3HZ LYS+ 132 19. 612-0. 745 4.261 1.00 0. 00 ATOM 158 QZ LYS+ 132 19. 584-0. 394 5.172 1.00 0.00 ATOM 159 C LYS+ 132 14.580-1.901 1.413 1. 00 0.00 ATOM 160 O LYS+ 132 14.478-2.890 0.690 1.00 0.00 ATOM 161 N CYS 133 13. 530-1. 254 1.888 1.00 0.00 ATOM 162 H CYS 133 13. 668-0. 474 2.460 1.00 0.00 ATOM 163 CA CYS 133 12. 175-1. 680 1.573 1.00 0.00 ATOM 164 HA CYS 133 12.206-2.729 1.323 1.00 0.00

ATOM 165 CB CYS 133 11.255-1.476 2.777 1.00 0.00 ATOM 166 1HB CYS 133 10.258-1.259 2.420 1.00 0.00 ATOM 167 2HB CYS 133 11.610-0.635 3.348 1.00 0.00 ATOM 168 QB CYS 133 10.934-0.947 2.884 1.00 0.00 ATOM 169 SG CYS 133 11.136-2.900 3.911 1.00 0.00 ATOM 170 C CYS 133 11.648-0.900 0.377 1.00 0.00 ATOM 171 O CYS 133 12.052 0.234 0. 143 1.00 0.00 ATOM 172 N LYS+ 134 10.737-1.504-0.368 1.00 0.00 ATOM 173 H LYS+ 134 10.436-2.405-0.122 1.00 0.00 ATOM 174 CA LYS+ 134 10.153-0.858-1.532 1.00 0.00 ATOM 175 HA LYS+ 134 10.849-0.108-1.878 1.00 0.00 ATOM 176 CB LYS+ 134 9.904-1.872-2.653 1.00 0.00 ATOM 177 1HB LYS+ 134 9.051-2.480-2.387 1.00 0.00 ATOM 178 2HB LYS+ 134 10.772-2.507-2.749 1.00 0.00 ATOM 179 QB LYS+ 134 9.912-2.493-2.568 1.00 0.00 ATOM 180 CG LYS+ 134 9.629-1.227-4.004 1.00 0.00 ATOM 181 1HG LYS+ 134 10.443-0.556-4.242 1.00 0.00 ATOM 182 2HG LYS+ 134 8.707-0.671-3.943 1.00 0.00 ATOM 183 QG LYS+ 134 9.575-0.613-4.092 1.00 0.00 ATOM 184 CD LYS+ 134 9.506-2.266-5. 111 1.00 0.00 ATOM 185 1HD LYS+ 134 9.374-3.241-4.662 1.00 0.00 ATOM 186 2HD LYS+ 134 10.413-2.261-5.698 1.00 0.00 ATOM 187 QD LYS+ 134 9.894-2.751-5.180 1.00 0.00 ATOM 188 CE LYS+ 134 8.324-1.980-6.030 1.00 0.00 ATOM 189 1HE LYS+ 134 7.558-2.722-5.850 1.00 0.00 ATOM 190 2HE LYS+ 134 8.657-2.053-7.056 1.00 0.00 ATOM 191 QE LYS+ 134 8.108-2.387-6.453 1.00 0.00 ATOM 192 NZ LYS+ 134 7.747-0.622-5.804 1.00 0.00 ATOM 193 1HZ LYS+ 134 8.501 0.055-5.575 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.067-0.649-5.015 1.00 0.00 ATOM 195 3HZ LYS+ 134 7.250-0.297-6.659 1.00 0.00 ATOM 196 QZ LYS+ 134 7.606-0.297-5.749 1.00 0.00 ATOM 197 C LYS+ 134 8.854-0.184-1.146 1.00 0.00 ATOM 198 O LYS+ 134 7.909-0.844-0.729 1.00 0.00 ATOM 199 N PHE 135 8.817 1.126-1.278 1.00 0.00 ATOM 200 H PHE 135 9.608 1.597-1.613 1.00 0.00 ATOM 201 CA PHE 135 7.633 1.889-0.929 1.00 0.00 ATOM 202 HA PHE 135 7.084 1.337-0. 180 1.00 0.00 ATOM 203 CB PHE 135 8.045 3.245-0.355 1.00 0.00 ATOM 204 1HB PHE 135 8.246 3.920-1.175 1.00 0.00 ATOM 205 2HB PHE 135 8.948 3.120 0.222 1.00 0.00 ATOM 206 QB PHE 135 8.597 3.520-0.476 1.00 0.00 ATOM 207 QD PHE 135 6.915 3.979 0.640 1.00 0.00 ATOM 208 QE PHE 135 5.278 5.080 2.107 1.00 0.00 ATOM 209 QR PHE 135 5.768 4.750 1.667 1.00 0.00 ATOM 210 CG PHE 135 7.027 3.903 0.538 1.00 0.00 ATOM 211 CD1 PHE 135 7.268 5.170 1.045 1.00 0.00 ATOM 212 1HD PHE 135 8.189 5.677 0.790 1.00 0.00 ATOM 213 CE1 PHE 135 6.350 5.791 1.868 1.00 0.00 ATOM 214 1HE PHE 135 6.553 6.779 2.256 1.00 0.00 ATOM 215 CZ PHE 135 5.175 5.148 2.196 1.00 0.00 ATOM 216 HZ PHE 135 4.454 5.631 2.842 1.00 0.00 ATOM 217 CE2 PHE 135 4.922 3.887 1.699 1.00 0.00 ATOM 218 2HE PHE 135 4.002 3.381 1.957 1.00 0.00 ATOM 219 CD2 PHE 135 5.843 3.269 0.875 1.00 0.00 ATOM 220 2HD PHE 135 5.641 2.281 0.490 1.00 0.00 ATOM 221 C PHE 135 6.752 2.087-2.150 1.00 0.00 ATOM 222 O PHE 135 7.200 2.589-3.180 1.00 0.00 ATOM 223 N LEU 136 5.503 1.692-2.022 1.00 0.00 ATOM 224 H LEU 136 5.212 1.301-1. 168 1. 00 0.00 ATOM 225 CA LEU 136 4.536 1.830-3.090 1.00 0.00 ATOM 226 HA LEU 136 5.036 2.268-3.942 1.00 0.00 ATOM 227 CB LEU 136 3.957 0.470-3.481 1. 00 0.00 ATOM 228 1HB LEU 136 3.112 0.638-4.134 1.00 0.00 ATOM 229 2HB LEU 136 3.602-0.019-2.584 1. 00 0.00 ATOM 230 QB LEU 136 3.357 0.310-3. 359 l. O0 0. 00 ATOM 231 CG LEU 136 4. 933-0.469-4.193 1. 00 0.00 ATOM 232 HG LEU 136 5.686 0.121-4.692 1. 00 0.00 ATOM 233 QD1 LEU 136 5. 792-1.591-2.953 1. 00 0.00 ATOM 234 QD2 LEU 136 4. 034-1.492-5.488 1. 00 0. 00 ATOM 235 CD1 LEU 136 5.629-1.376-3.192 1. 00 0.00 ATOM 236 1HD1 LEU 136 6.517-0.888-2. 818 1. 00 0. 00

ATOM 237 2HD1 LEU 136 5.900-2.304-3.673 1.00 0.00 ATOM 238 3HD1 LEU 136 4.959-1.581-2.369 1.00 0.00 ATOM 239 CD2 LEU 136 4.207-1.296-5.241 1.00 0.00 ATOM 240 1HD2 LEU 136 3.156-1.341-4.996 1.00 0.00 ATOM 241 2HD2 LEU 136 4.615-2.297-5.257 1.00 0. 00 ATOM 242 3HD2 LEU 136 4.331-0.840-6.212 1.00 0.00 ATOM 243 QQD LEU 136 4.913-1.542-4.221 1.00 0.00 ATOM 244 C LEU 136 3.438 2.768-2.626 1.00 0. 00 ATOM 245 O LEU 136 2.343 2.342-2.273 1.00 0.00 ATOM 246 N HIS+ 137 3.768 4.048-2. 598 1.00 0.00 ATOM 247 H HIS+ 137 4.671 4.309-2.871 1.00 0.00 ATOM 248 CA HIS+ 137 2.848 5.079-2.153 1.00 0.00 ATOM 249 HA HIS+ 137 2.140 4.633-1.463 1.00 0. 00 ATOM 250 CB HIS+ 137 3.638 6.184-1.441 1.00 0.00 ATOM 251 1HB HIS+ 137 4.161 6.770-2.184 1.00 0.00 ATOM 252 2HB HIS+ 137 4.362 5.727-0.782 1.00 0.00 ATOM 253 QB HIS+ 137 4.262 6. 249-1.483 1.00 0.00 ATOM 254 CG HIS+ 137 2.806 7.118-0.623 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.739 7.825-1.128 1.00 0.00 ATOM 256 CD2 HIS+ 137 2.887 7.447 0.683 1.00 0.00 ATOM 257 1HD HIS+ 137 1.424 7.804-2.058 1.00 0.00 ATOM 258 CE1 HIS+ 137 1.199 8.547-0.164 1.00 0.00 ATOM 259 NE2 HIS+ 137 1.875 8.333 0.954 1.00 0.00 ATOM 260 2HD HIS+ 137 3.614 7.072 1.391 1.00 0.00 ATOM 261 1HE HIS+ 137 0.344 9.201-0.268 1.00 0.00 ATOM 262 2HE HIS+ 137 1.500 8.472 1.857 1.00 0.00 ATOM 263 C HIS+ 137 2.111 5.663-3.347 1.00 0.00 ATOM 264 O HIS+ 137 2.613 6.575-4.007 1.00 0.00 ATOM 265 N GLN 138 0.930 5.141-3.635 1.00 0.00 ATOM 266 H GLN 138 0.568 4.411-3.075 1.00 0.00 ATOM 267 CA GLN 138 0.158 5.630-4.767 1.00 0.00 ATOM 268 HA GLN 138 0.530 6.613-5.013 1.00 0.00 ATOM 269 CB GLN 138 0.355 4.714-5.978 1.00 0.00 ATOM 270 1HB GLN 138-0.493 4.823-6.638 1.00 0.00 ATOM 271 2HB GLN 138 0.404 3.691-5.636 1.00 0.00 ATOM 272 QB GLN 138-0.044 4.257-6.137 1.00 0.00 ATOM 273 CG GLN 138 1.621 5.014-6.773 1.00 0.00 ATOM 274 1HG GLN 138 1.939 6.022-6.548 1.00 0. 00 ATOM 275 2HG GLN 138 1.396 4.937-7.826 1.00 0. 00 ATOM 276 QG GLN 138 1.668 5.480-7.187 1.00 0.00 ATOM 277 CD GLN 138 2.761 4.063-6.452 1.00 0.00 ATOM 278 OE1 GLN 138 2.592 2.845-6.468 1.00 0.00 ATOM 279 NE2 GLN 138 3.934 4.613-6.158 1.00 0.00 ATOM 280 1HE2 GLN 138 4.005 5.591-6.161 1.00 0.00 ATOM 281 2HE2 GLN 138 4.683 4.018-5.952 1.00 0.00 ATOM 282 QE2 GLN 138 4.344 4.805-6.056 1.00 0.00 ATOM 283 C GLN 138-1.321 5.741-4.425 1.00 0.00 ATOM 284 O GLN 138-1.889 4.871-3.764 1.00 0.00 ATOM 285 N GLU 139-1.934 6.820-4.887 1.00 0.00 ATOM 286 H GLU 139-1.422 7.469-5.409 1.00 0.00 ATOM 287 CA GLU 139-3.346 7.067-4.645 1.. 00 0. 00 ATOM 288 HA GLU 139-3.634 6.532-3.749 1.00 0.00 ATOM 289 CB GLU 139-3.590 8.561-4.435 1.00 0.00 ATOM 290 1HB GLU 139-4.643 8.717-4.251 1.00 0.00 ATOM 291 2HB GLU 139-3.308 9.090-5.332 1.00 0.00 ATOM 292 QB GLU 139-3.975 8.904-4.791 1.00 0.00 ATOM 293 CG GLU 139-2.813 9.150-3.269 1.00 0.00 ATOM 294 1HG GLU 139-2.525 10.161-3.517 1.00 0.00 ATOM 295 2HG GLU 139-1.929 8.554-3.099 1.00 0.00 ATOM 296 QG GLU 139-2.227 9.358-3.308 1.00 0.00 ATOM 297 CD GLU 139-3.628 9.178-1.996 1.00 0.00 ATOM 298 OE1 GLU 139-3.557 10.186-1.266 1.00 0.00 ATOM 299 OE2 GLU 139-4.343 8.190-1.732 1.00 0.00 ATOM 300 C GLU 139-4.186 6.568-5.813 1.00 0.00 ATOM 301 O GLU 139-4.007 7.001-6.952 1.00 0.00 ATOM 302 N ARG+ 140-5.103 5.666-5.521 1.00 0.00 ATOM 303 H ARG+ 140-5.202 5.368-4.590 1.00 0. 00 ATOM 304 CA ARG+ 140-5.984 5.111-6.534 1.00 0.00 ATOM 305 HA ARG+ 140-5.655 5.466-7.499 1.00 0.00 ATOM 306 CB ARG+ 140-5.917 3.578-6.506 1.00 0. 00 ATOM 307 1HB ARG+ 140-6.368 3.230-5.587 1.00 0.00 ATOM 308 2HB ARG+ 140-4.881 3.274-6.524 1.00 0.00

ATOM 309 QB ARG+ 140-5.624 3.252-6.055 1.00 0.00 ATOM 310 CG ARG+ 140-6.631 2.905-7.668 1.00 0.00 ATOM 311 1HG ARG+ 140-7.674 3.191-7.648 1.00 0.00 ATOM 312 2HG ARG+ 140-6. 549 1.835-7.556 1.00 0.00 ATOM 313 QG ARG+ 140-7.111 2.513-7.602 1.00 0.00 ATOM 314 CD ARG+ 140-6. 034 3.309-9.005 1.00 0.00 ATOM 315 1HD ARG+ 140-5.138 3.887-8.825 1.00 0.00 ATOM 316 2HD ARG+ 140-6.754 3.921-9.537 1.00 0.00 ATOM 317 QD ARG+ 140-5.946 3.904-9.181 1.00 0.00 ATOM 318 NE ARG+ 140-5.696 2.148-9.826 1.00 0.00 ATOM 319 HE ARG+ 140-5.209 1.416-9.389 1.00 0.00 ATOM 320 CZ ARG+ 140-5.996 2.045-11.121 1.00 0.00 ATOM 321 NH1 ARG+ 140-6. 707 2.996-11.720 1.00 0.00 ATOM 322 1HH1 ARG+ 140-7. 029 3.801-11.193 1.00 0.00 ATOM 323 2HH1 ARG+ 140-6.934 2.925-12.690 1.00 0.00 ATOM 324 QH1 ARG+ 140-6.981 3.363-11.941 1.00 0.00 ATOM 325 NH2 ARG+ 140-5.601 0.979-11.810 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.081 0.253-11.358 1. 00 0.00 ATOM 327 2HH2 ARG+ 140-5.824 0.898-12.782 1.00 0.00 ATOM 328 QH2 ARG+ 140-5.452 0.576-12.070 1.00 0. 00 ATOM 329 C ARG+ 140-7.412 5.584-6.286 1.00 0.00 ATOM 330 O ARG+ 140-8.214 4.869-5.685 1.00 0.00 ATOM 331 N MET 141-7.727 6.792-6.745 1. 00 0.00 ATOM 332 H MET 141-7.045 7.316-7.215 1.00 0.00 ATOM 333 CA MET 141-9. 065 7.361-6.560 1.00 0.00 ATOM 334 HA MET 141-9. 364 7.170-5.541 1.00 0.00 ATOM 335 CB MET 141-9.037 8.875-6.795 1.00 0.00 ATOM 336 1HB MET 141-9.250 9.068-7.837 1.00 0.00 ATOM 337 2HB MET 141-8. 050 9.248-6.563 1.00 0.00 ATOM 338 QB MET 141-8.650 9.158-7.200 1.00 0.00 ATOM 339 CG MET 141-10.048 9.639-5.954 1.00 0.00 ATOM 340 1HG MET 141-9.681 9.694-4.939 1.00 0.00 ATOM 341 2HG MET 141-10.983 9.099-5.969 1.00 0.00 ATOM 342 QG MET 141-10.332 9.397-5.454 1.00 0.00 ATOM 343 SD MET 141-10.342 11.312-6.556 1.00 0.00 ATOM 344 QE MET 141-8.893 12.429-5.421 1.00 0.00 ATOM 345 CE MET 141-9.136 12.241-5.611 1.00 0.00 ATOM 346 1HE MET 141-9.050 11.820-4.619 1.00 0.00 ATOM 347 2HE MET 141-9. 453 13.271-5.538 1.00 0.00 ATOM 348 3HE MET 141-8.177 12.195-6.106 1.00 0.00 ATOM 349 C MET 141-10.081 6. 705-7.499 1.00 0.00 ATOM 350 O MET 141-11.015 7.353-7.972 1.00 0.00 ATOM 351 N ASP 142-9.890 5.418-7.747 1.00 0.00 ATOM 352 H ASP 142-9. 132 4.965-7.324 1.00 0.00 ATOM 353 CA ASP 142-10.762 4.650-8.613 1.00 0.00 ATOM 354 HA ASP 142-11.466 5. 324-9.077 1.00 0.00 ATOM 355 CB ASP 142-9.937 3.949-9.694 1.00 0.00 ATOM 356 1HB ASP 142-10. 589 3.314-10.266 1.00 0. 00 ATOM 357 2HB ASP 142-9.181 3.342-9.221 1. 00 0.00 ATOM 358 QB ASP 142-9.885 3.328-9.743 1.00 0.00 ATOM 359 CG ASP 142-9.251 4.909-10.639 1.00 0.00 ATOM 360 OD1 ASP 142-8.007 5.021-10.565 1.00 0.00 ATOM 361 OD2 ASP 142-9.944 5.530-11.463 1.00 0.00 ATOM 362 C ASP 142-11.513 3.599-7.812 1.00 0.00 ATOM 363 O ASP 142-12.732 3.469-7.910 1.00 0.00 ATOM 364 N VAL 143-10.764 2.834-7.029 1.00 0.00 ATOM 365 H VAL 143-9. 797 2.980-7.004 1.00 0.00 ATOM 366 CA VAL 143-11.340 1.772-6.223 1.00 0.00 ATOM 367 HA VAL 143-12.268 1.471-6.690 1.00 0.00 ATOM 368 CB VAL 143-10.401 0.546-6.172 1.00 0.00 ATOM 369 HB VAL 143-9. 799 0.619-5.276 1.00 0.00 ATOM 370 QG1 VAL 143-11.387-1.052-6.082 1.00 0.00 ATOM 371 QG2 VAL 143-9.242 0.519-7.655 1.00 0.00 ATOM 372 CG1 VAL 143-11.200-0.745-6.099 1.00 0.00 ATOM 373 1HG1 VAL 143-11.521-0.915-5.082 1.00 0.00 ATOM 374 2HG1 VAL 143-10. 577-1.568-6.422 1.00 0.00 ATOM 375 3HG1 VAL 143-12.062-0.673-6.744 1.00 0.00 ATOM 376 CG2 VAL 143-9.464 0.523-7.372 1.00 0.00 ATOM 377 1HG2 VAL 143-8.468 0.799-7.056 1.00 0.00 ATOM 378 2HG2 VAL 143-9.813 1.226-8.115 1.00 0.00 ATOM 379 3HG2 VAL 143-9.445-0.470-7.796 1.00 0.00 ATOM 380 QQG VAL 143-10.314-0.267-6. 869 1. 00 0. 00

ATOM 381 C VAL 143-11.639 2.274-4.808 1.00 0.00 ATOM 382 O VAL 143-11.092 3.284-4.371 1.00 0.00 ATOM 383 N CYS 144-12.533 1.586-4.108 1.00 0.00 ATOM 384 H CYS 144-12.955 0.799-4.513 1.00 0.00 ATOM 385 CA CYS 144-12.928 1.985-2.758 1.00 0.00 ATOM 386 HA CYS 144-12.117 2.548-2.308 1.00 0.00 ATOM 387 CB CYS 144-14.169 2.878-2.859 1.00 0.00 ATOM 388 1HB CYS 144-14.891 2.395-3.502 1.00 0.00 ATOM 389 2HB CYS 144-13.886 3.823-3.298 1.00 0.00 ATOM 390 QB CYS 144-14.388 3.109-3.400 1.00 0.00 ATOM 391 SG CYS 144-14.993 3.233-1.277 1.00 0.00 ATOM 392 C CYS 144-13.224 0.767-1.893 1.00 0.00 ATOM 393 O CYS 144-14.320 0.215-1.952 1.00 0.00 ATOM 394 N GLU 145-12.247 0.348-1.095 1.00 0.00 ATOM 395 H GLU 145-11.389 0. 818-1. 089 1.00 0.00 ATOM 396 CA GLU 145-12.418-0.808-0.235 1.00 0. 00 ATOM 397 HA GLU 145-13.468-1.052-0.213 1.00 0.00 ATOM 398 CB GLU 145-11.658-1.993-0.801 1.00 0.00 ATOM 399 1HB GLU 145-11.341-2.623 0.014 1.00 0.00 ATOM 400 2HB GLU 145-10.785-1.635-1.326 1.00 0.00 ATOM 401 QB GLU 145-11.063-2.129-0.656 1.00 0.00 ATOM 402 CG GLU 145-12.503-2.828-1.744 1.00 0.00 ATOM 403 1HG GLU 145-11.935-3.691-2.055 1.00 0.00 ATOM 404 2HG GLU 145-12.760-2.231-2.607 1.00 0.00 ATOM 405 QG GLU 145-12.347-2.961-2.331 1.00 0. 00 ATOM 406 CD GLU 145-13.778-3.298-1.078 1.00 0.00 ATOM 407 OE1 GLU 145-13.709-3.709 0.102 1.00 0.00 ATOM 408 OE2 GLU 145-14.841-3.245-1.721 1.00 0.00 ATOM 409 C GLU 145-11.948-0.530 1.178 1.00 0.00 ATOM 410 O GLU 145-11.425 0.545 1.475 1.00 0.00 ATOM 411 N THR 146-12.142-1.514 2.040 1.00 0.00 ATOM 412 H THR 146-12.563-2.343 1.721 1.00 0.00 ATOM 413 CA THR 146-11.752-1.412 3.437 1.00 0.00 ATOM 414 HA THR 146-12.110-0.464 3.813 1.00 0.00 ATOM 415 CB THR 146-12.409-2.547 4.233 1.00 0.00 ATOM 416 HB THR 146-11.937-3.481 3.964 1.00 0.00 ATOM 417 QG2 THR 146-12.285-2.352 6.096 1.00 0.00 ATOM 418 OG1 THR 146-13.785-2.638 3.914 1.00 0.00 ATOM 419 1HG THR 146-14.298-2.130 4.562 1.00 0.00 ATOM 420 CG2 THR 146-12.308-2.390 5.737 1.00 0.00 ATOM 421 1HG2 THR 146-12.718-3.266 6.220 1.00 0.00 ATOM 422 2HG2 THR 146-12.865-1.516 6.046 1.00 0.00 ATOM 423 3HG2 THR 146-11.273-2.275 6.020 1.00 0.00 ATOM 424 C THR 146-10.232-1.460 3. 583 1.00 0.00 ATOM 425 0 THR 146-9.524-1.904 2.677 1.00 0.00 ATOM 426 N HIS+ 147-9.745-1.010 4.739 1.00 0.00 ATOM 427 H HIS+ 147-10.375-0.677 5.415 1.00 0.00 ATOM 428 CA HIS+ 147-8.315-1.001 5.043 1.00 0.00 ATOM 429 HA HIS+ 147-7.832-0.304 4.375 1.00 0.00 ATOM 430 CB HIS+ 147-8.101-0.543 6.491 1.00 0.00 ATOM 431 1HB HIS+ 147-8.050-1.415 7.128 1.00 0.00 ATOM 432 2HB HIS+ 147-8.939 0.065 6.794 1.00 0.00 ATOM 433 QB HIS+ 147-8.494-0.675 6.961 1.00 0.00 ATOM 434 CG HIS+ 147-6.853 0.259 6.710 1.00 0.00 ATOM 435 ND1 HIS+ 147-6.836 1.639 6.722 1.00 0. 00 ATOM 436 CD2 HIS+ 147-5.579-0.132 6.957 1.00 0.00 ATOM 437 1HD HIS+ 147-7.611 2.227 6.564 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.608 2.062 6.968 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.827 1.008 7.115 1.00 0.00 ATOM 440 2HD HIS+ 147-5.217-1.152 7.001 1.00 0.00 ATOM 441 1HE HIS+ 147-5.297 3.095 7.039 1.00 0.00 ATOM 442 2HE HIS+ 147-3.881 1.037 7.379 1.00 0.00 ATOM 443 C HIS+ 147-7.706-2.389 4.846 1.00 0.00 ATOM 444 O HIS+ 147-6.538-2.520 4.492 1.00 0.00 ATOM 445 N LEU 148-8.509-3.420 5.080 1.00 0.00 ATOM 446 H LEU 148-9.431-3.250 5.360 1.00 0.00 ATOM 447 CA LEU 148-8.055-4.796 4.931 1.00 0. 00 ATOM 448 HA LEU 148-7.110-4.888 5.445 1.00 0.00 ATOM 449 CB LEU 148-9.060-5.759 5.568 1.00 0.00 ATOM 450 1HB LEU 148-9.793-6.026 4.821 1.00 0.00 ATOM 451 2HB LEU 148-9. 562-5.241 6.373 1.00 0.00 ATOM 452 QB LEU 148-9.677-5.633 5.597 1.00 0.00

ATOM 453 CG LEU 148-8.456-7.048 6.128 1.00 0.00 ATOM 454 HG LEU 148-7.380-6.952 6.157 1.00 0.00 ATOM 455 QD1 LEU 148-9.058-7.354 7.882 1.00 0.00 ATOM 456 QD2 LEU 148-8.880-8.510 5.025 1.00 0.00 ATOM 457 CD1 LEU 148-8.942-7.295 7.545 1.00 0.00 ATOM 458 1HD1 LEU 148-10.003-7.498 7.532 1.00 0.00 ATOM 459 2HD1 LEU 148-8. 750-6.422 8.151 1.00 0.00 ATOM 460 3HD1 LEU 148-8. 420-8.144 7.962 1.00 0.00 ATOM 461 CD2 LEU 148-8.799-8.230 5.235 1.00 0.00 ATOM 462 1HD2 LEU 148-8.664-9.148 5.788 1.00 0.00 ATOM 463 2HD2 LEU 148-8.149-8.232 4.373 1.00 0.00 ATOM 464 3HD2 LEU 148-9.827-8.152 4.913 1.00 0.00 ATOM 465 QQD LEU 148-8. 969-7.932 6.453 1.00 0.00 ATOM 466 C LEU 148-7. 851-5.161 3.464 1.00 0.00 ATOM 467 O LEU 148-6. 903-5.868 3.129 1.00 0.00 ATOM 468 N HIS+ 149-8.739-4.687 2.590 1.00 0.00 ATOM 469 H HIS+ 149-9.478-4.129 2.907 1.00 0.00 ATOM 470 CA HIS+ 149-8.628-4.993 1.166 1.00 0.00 ATOM 471 HA HIS+ 149-8.592-6.070 1.078 1.00 0.00 ATOM 472 CB HIS+ 149-9.836-4.489 0.376 1.00 0.00 ATOM 473 1HB HIS+ 149-9.511-3.750-0.344 1.00 0.00 ATOM 474 2HB HIS+ 149-10.550-4.035 1.049 1.00 0.00 ATOM 475 QB HIS+ 149-10.030-3.892 0.353 1.00 0.00 ATOM 476 CG HIS+ 149-10.523-5.593-0.371 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.891-5.697-0.483 1.00 0.00 ATOM 478 CD2 HIS+ 149-10. 011-6.657-1.037 1.00 0.00 ATOM 479 1HD HIS+ 149-12.555-5.051-0.122 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.193-6.776-1.183 1.00 0.00 ATOM 481 NE2 HIS+ 149-11. 070-7.376-1.533 1.00 0.00 ATOM 482 2HD HIS+ 149-8.963-6.901-1.149 1.00 0.00 ATOM 483 1HE HIS+ 149-13.192-7.108-1.430 1.00 0.00 ATOM 484 2HE HIS+ 149-11.003-8.117-2.170 1.00 0.00 ATOM 485 C HIS+ 149-7.343-4.437 0.586 1.00 0.00 ATOM 486 O HIS+ 149-6.571-5.179-0.010 1.00 0.00 ATOM 487 N TRP 150-7. 100-3.144 0.771 1.00 0.00 ATOM 488 H TRP 150-7.751-2.595 1.261 1.00 0.00 ATOM 489 CA TRP 150-5.871-2.530 0.263 1.00 0.00 ATOM 490 HA TRP 150-5.828-2.700-0.803 1.00 0.00 ATOM 491 CB TRP 150-5.835-1.029 0.545 1.00 0.00 ATOM 492 1HB TRP 150-4.892-0.632 0.194 1.00 0.00 ATOM 493 2HB TRP 150-5. 904-0.871 1.611 1.00 0.00 ATOM 494 QB TRP 150-5.398-0.751 0.903 1.00 0.00 ATOM 495 CG TRP 150-6.934-0.245-0.105 1.00 0.00 ATOM 496 CD1 TRP 150-7.394 0.979 0.285 1.00 0.00 ATOM 497 CD2 TRP 150-7.703-0.613-1.254 1.00 0.00 ATOM 498 CE3 TRP 150-7.717-1.725-2.101 1.00 0.00 ATOM 499 CE2 TRP 150-8. 609 0.433-1.497 1.00 0.00 ATOM 500 NE1 TRP 150-8. 402 1.390-0.545 1.00 0.00 ATOM 501 HD TRP 150-7.011 1.531 1.130 1.00 0.00 ATOM 502 3HE TRP 150-7. 039-2.549-1.950 1.00 0.00 ATOM 503 CZ3 TRP 150-8.617-1.755-3.141 1.00 0.00 ATOM 504 CZ2 TRP 150-9. 513 0.401-2.547 1.00 0.00 ATOM 505 1HE TRP 150-8.893 2.235-0.468 1.00 0.00 ATOM 506 3HZ TRP 150-8. 647-2.606-3.804 1.00 0.00 ATOM 507 CH2 TRP 150-9. 503-0.698-3.355 1.00 0.00 ATOM 508 2HZ TRP 150-10.206 1.209-2.731 1.00 0.00 ATOM 509 HH TRP 150-10.193-0.765-4.183 1.00 0.00 ATOM 510 C TRP 150-4.661-3.190 0.889 1.00 0.00 ATOM 511 O TRP 150-3.636-3.332 0.243 1.00 0.00 ATOM 512 N HIS+ 151-4.797-3.616 2.139 1.00 0. 00 ATOM 513 H HIS+ 151-5.654-3.491 2.597 1.00 0.00 ATOM 514 CA HIS+ 151-3.713-4.296 2.829 1.00 0.00 ATOM 515 HA HIS+ 151-2.853-3.644 2.831 1.00 0.00 ATOM 516 CB HIS+ 151-4.126-4.614 4.279 1.00 0.00 ATOM 517 1HB HIS+ 151-5.035-5.201 4.258 1. 00 0. 00 ATOM 518 2HB HIS+ 151-4.323-3.688 4.796 1.00 0.00 ATOM 519 QB HIS+ 151-4. 679-4.444 4.527 1.00 0.00 ATOM 520 CG HIS+ 151-3.109-5.376 5.085 1. 00 0. 00 ATOM 521 ND1 HIS+ 151-2.689-4.975 6.334 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.453-6.534 4.829 1. 00 0. 00 ATOM 523 1HD HIS+ 151-2.982-4.166 6.807 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.823-5.853 6. 808 1. O0 0.00

ATOM 525 NE2 HIS+ 151-1.663-6.808 5.915 1.00 0.00 ATOM 526 2HD HIS+ 151-2.531-7.125 3.924 1.00 0.00 ATOM 527 1HE HIS+ 151-1. 321-5.792 7.764 1.00 0.00 ATOM 528 2HE HIS+ 151-1.193-7. 653 6.076 1.00 0.00 ATOM 529 C HIS+ 151-3. 374-5.576 2.076 1.00 0.00 ATOM 530 O HIS+ 151-2.205-5.884 1.847 1.00 0.00 ATOM 531 N THR 152-4.410-6. 309 1.689 1.00 0.00 ATOM 532 H THR 152-5.317-6.004 1.898 1.00 0.00 ATOM 533 CA THR 152-4.234-7. 550 0.956 1.00 0.00 ATOM 534 HA THR 152-3.486-8. 132 1.473 1.00 0.00 ATOM 535 CB THR 152-5.541-8.346 0.915 1.00 0.00 ATOM 536 HB THR 152-6.184-7.928 0.152 1.00 0.00 ATOM 537 QG2 THR 152-5.290-10.160 0.523 1.00 0.00 ATOM 538 OG1 THR 152-6.212-8. 273 2.163 1.00 0.00 ATOM 539 1HG THR 152-6. 427-7.355 2.364 1. 00 0. 00 ATOM 540 CG2 THR 152-5.339-9. 812 0.599 1.00 0.00 ATOM 541 1HG2 THR 152-5.126-9.928-0.456 1.00 0.00 ATOM 542 2HG2 THR 152-6.234-10.360 0.848 1.00 0.00 ATOM 543 3HG2 THR 152-4.511-10.194 1.176 1.00 0.00 ATOM 544 C THR 152-3.725-7.277-0.451 1.00 0.00 ATOM 545 O THR 152-2.743-7.871-0.856 1.00 0.00 ATOM 546 N VAL 153-4.374-6.363-1.177 1.00 0.00 ATOM 547 H VAL 153-5.147-5.896-0.788 1.00 0.00 ATOM 548 CA VAL 153-3.942-6.025-2.534 1.00 0.00 ATOM 549 HA VAL 153-4.027-6.915-3.137 1.00 0.00 ATOM 550 CB VAL 153-4.824-4.919-3. 159 1.00 0.00 ATOM 551 HB VAL 153-4.708-4.018-2.575 1.00 0.00 ATOM 552 QG1 VAL 153-4.290-4.550-4. 925 1.00 0.00 ATOM 553 QG2 VAL 153-6.636-5.420-3. 120 1.00 0.00 ATOM 554 CG1 VAL 153-4.392-4.620-4.587 1.00 0.00 ATOM 555 1HG1 VAL 153-3.366-4.930-4.725 1.00 0.00 ATOM 556 2HG1 VAL 153-4.477-3.560-4.775 1.00 0.00 ATOM 557 3HG1 VAL 153-5.026-5.160-5.275 1.00 0.00 ATOM 558 CG2 VAL 153-6.290-5.324-3. 128 1.00 0.00 ATOM 559 1HG2 VAL 153-6.677-5.200-2. 127 1.00 0.00 ATOM 560 2HG2 VAL 153-6.382-6.359-3.424 1.00 0.00 ATOM 561 3HG2 VAL 153-6.850-4.703-3.811 1.00 0.00 ATOM 562 QQG VAL 153-5.463-4.985-4. 023 1.00 0.00 ATOM 563 C VAL 153-2.485-5.583-2.524 1.00 0.00 ATOM 564 O VAL 153-1.683-6.010-3.356 1.00 0.00 ATOM 565 N ALA 154-2.150-4.746-1.556 1.00 0.00 ATOM 566 H ALA 154-2.842-4.460-0.914 1.00 0.00 ATOM 567 CA ALA 154-0.791-4.256-1.397 1.00 0.00 ATOM 568 HA ALA 154-0. 491-3.772-2.315 1.00 0.00 ATOM 569 QB ALA 154-0. 732-2.994-0.009 1.00 0.00 ATOM 570 CB ALA 154-0.744-3.237-0.275 1.00 0.00 ATOM 571 1HB ALA 154-0.123-2.404-0.572 1.00 0. 00 ATOM 572 2HB ALA 154-0.331-3.696 0.611 1.00 0.00 ATOM 573 3HB ALA 154-1.743-2.884-0. 066 1.00 0.00 ATOM 574 C ALA 154 0.166-5.404-1.100 1.00 0.00 ATOM 575 O ALA 154 1.198-5.557-1. 756 1.00 0.00 ATOM 576 N LYS+ 155-0.186-6.212-0. 103 1.00 0.00 ATOM 577 H LYS+ 155-1. 024-6.036 0.381 1.00 0.00 ATOM 578 CA LYS+ 155 0.636-7.349 0.287 1.00 0.00 ATOM 579 HA LYS+ 155 1.628-6.977 0.520 1.00 0.00 ATOM 580 CB LYS+ 155 0.056-8.044 1.524 1.00 0.00 ATOM 581 1HB LYS+ 155-0.787-8.647 1.219 1.00 0.00 ATOM 582 2HB LYS+ 155-0.286-7.290 2.219 1.00 0.00 ATOM 583 QB LYS+ 155-0.536-7.968 1.719 1.00 0.00 ATOM 584 CG LYS+ 155 1.053-8.943 2.245 1.00 0.00 ATOM 585 1HG LYS+ 155 1.663-8.334 2.898 1.00 0.00 ATOM 586 2HG LYS+ 155 1.682-9.426 1.511 1.00 0.00 ATOM 587 QG LYS+ 155 1.673-8.880 2.205 1.00 0.00 ATOM 588 CD LYS+ 155 0.354-10.010 3.074 1.00 0. 00 ATOM 589 1HD LYS+ 155-0. 676-10. 084 2.755 1.00 0.00 ATOM 590 2HD LYS+ 155 0. 390-9.723 4.116 1.00 0.00 ATOM 591 QD LYS+ 155-0. 143-9. 903 3.436 1.00 0.00 ATOM 592 CE LYS+ 155 1.021-11.370 2.915 1. 00 0. 00 ATOM 593 1HE LYS+ 155 0.449-12.103 3.466 1.00 0.00 ATOM 594 2HE LYS+ 155 2.022-11.316 3.323 1.00 0.00 ATOM 595 QE LYS+ 155 1.236-11.709 3.395 1.00 0.00 ATOM 596 NZ LYS+ 155 1.101-11.787 1.485 1.00 0.00

ATOM 597 1HZ LYS+ 155 2.013-11.475 1.066 1.00 0.00 ATOM 598 2HZ LYS+ 155 0.322-11.362 0.940 1.00 0.00 ATOM 599 3HZ LYS+ 155 1.038-12.822 1.407 1.00 0.00 ATOM 600 QZ LYS+ 155 1.124-11.886 1.138 1.00 0.00 ATOM 601 C LYS+ 155 0.749-8.342-0.856 1.00 0.00 ATOM 602 O LYS+ 155 1.826-8.860-1. 110 1.00 0.00 ATOM 603 N GLU 156-0.363-8.600-1. 536 1.00 0.00 ATOM 604 H GLU 156-1.203-8.150-1.275 1.00 0.00 ATOM 605 CA GLU 156-0.383-9.528-2. 658 1.00 0.00 ATOM 606 HA GLU 156-0. 079-10.496-2.293 1.00 0.00 ATOM 607 CB GLU 156-1.790-9.640-3.247 1.00 0.00 ATOM 608 1HB GLU 156-1. 716-10.007-4.260 1.00 0.00 ATOM 609 2HB GLU 156-2.244-8.659-3.263 1.00 0.00 ATOM 610 QB GLU 156-1.980-9.333-3.761 1.00 0.00 ATOM 611 CG GLU 156-2.706-10.571-2.470 1.00 0.00 ATOM 612 1HG GLU 156-2.541-10. 422-1.414 1.00 0.00 ATOM 613 2HG GLU 156-2.469-11.591-2.731 1.00 0.00 ATOM 614 QG GLU 156-2.505-11.006-2.072 1.00 0.00 ATOM 615 CD GLU 156-4.170-10.323-2.769 1.00 0.00 ATOM 616 OE1 GLU 156-4.505-9.204-3.209 1.00 0.00 ATOM 617 OE2 GLU 156-4.981-11.244-2.559 1.00 0.00 ATOM 618 C GLU 156 0.594-9.085-3.737 1.00 0.00 ATOM 619 O GLU 156 1.431-9.866-4.162 1.00 0.00 ATOM 620 N THR 157 0.488-7.828-4.161 1.00 0.00 ATOM 621 H THR 157-0.205-7.250-3.771 1.00 0.00 ATOM 622 CA THR 157 1.376-7.282-5.191 1.00 0.00 ATOM 623 HA THR 157 1.171-7.809-6.112 1.00 0.00 ATOM 624 CB THR 157 1.091-5.790-5.400 1.00 0.00 ATOM 625 HB THR 157 1.407-5.247-4.520 1.00 0.00 ATOM 626 QG2 THR 157 1.983-5.058-6.877 1.00 0.00 ATOM 627 OG1 THR 157-0.295-5.560-5.592 1.00 0.00 ATOM 628 1HG THR 157-0.787-5.849-4.810 1.00 0.00 ATOM 629 CG2 THR 157 1.812-5.198-6.593 1.00 0.00 ATOM 630 1HG2 THR 157 2.194-4.222-6.336 1.00 0.00 ATOM 631 2HG2 THR 157 1.124-5.109-7.421 1.00 0.00 ATOM 632 3HG2 THR 157 2.632-5.844-6.875 1.00 0.00 ATOM 633 C THR 157 2.853-7.491-4.829 1.00 0.00 ATOM 634 O THR 157 3.674-7.818-5.685 1.00 0.00 ATOM 635 N CYS 158 3.192-7.297-3.561 1.00 0.00 ATOM 636 H CYS 158 2.503-7.028-2.911 1.00 0.00 ATOM 637 CA CYS 158 4.571-7.468-3.117 1.00 0.00 ATOM 638 HA CYS 158 5.213-7.072-3.888 1.00 0.00 ATOM 639 CB CYS 158 4.802-6.674-1.832 1.00 0.00 ATOM 640 1HB CYS 158 5.673-7.055-1.330 1.00 0.00 ATOM 641 2HB CYS 158 3.944-6.792-1.189 1.00 0.00 ATOM 642 QB CYS 158 4.809-6.923-1.259 1.00 0.00 ATOM 643 SG CYS 158 5.044-4.882-2.115 1.00 0.00 ATOM 644 C CYS 158 4.918-8.950-2.920 1.00 0.00 ATOM 645 O CYS 158 5.955-9.414-3.392 1.00 0.00 ATOM 646 N SER 159 4.052-9.685-2.225 1.00 0.00 ATOM 647 H SER 159 3.245-9.258-1.868 1.00 0.00 ATOM 648 CA SER 159 4.269-11.110-1.967 1.00 0.00 ATOM 649 HA SER 159 5.245-11.211-1. 516 1.00 0. 00 ATOM 650 CB SER 159 3.225-11.644-0.991 1.00 0.00 ATOM 651 1HB SER 159 3.290-12.722-0.956 1.00 0.00 ATOM 652 2HB SER 159 2.240-11.352-1.329 1.00 0.00 ATOM 653 QB SER 159 2.765-12.037-1.142 1.00 0.00 ATOM 654 OG SER 159 3.435-11.126 0.317 1.00 0.00 ATOM 655 HG SER 159 4.366-10.883 0.413 1.00 0. 00 ATOM 656 C SER 159 4.249-11.947-3.249 1.00 0.00 ATOM 657 O SER 159 4.865-13.008-3.295 1.00 0.00 ATOM 658 N GLU 160 3.552-11.471-4.285 1.00 0.00 ATOM 659 H GLU 160 3.078-10. 615-4.196 1.00 0.00 ATOM 660 CA GLU 160 3.492-12.188-5.560 1.00 0.00 ATOM 661 HA GLU 160 3.178-13.203-5.364 1.00 0. 00 ATOM 662 CB GLU 160 2.499-11.518-6.517 1. 00 0. 00 ATOM 663 1HB GLU 160 3.022-10.774-7.100 1. 00 0.00 ATOM 664 2HB GLU 160 1.730-11.030-5.937 1. 00 o. oo ATOM 665 QB GLU 160 2.376-10.902-6.518 1. 00 0.00 ATOM 666 CG GLU 160 1.825-12.485-7. 480 1.00 0.00 ATOM 667 1HG GLU 160 1.134-13.103-6-926 1. 00 0. 00 ATOM 668 2HG GLU 160 2.581-13.108-7.933 1. 00 0. 00

ATOM 669 QG GLU 160 1.858-13.105-7.429 1.00 0.00 ATOM 670 CD GLU 160 1.065-11.775-8.580 1.00 0.00 ATOM 671 OE1 GLU 160 1.523-10.699-9.019 1.00 0.00 ATOM 672 OE2 GLU 160 0.011-12.294-9.001 1.00 0.00 ATOM 673 C GLU 160 4.885-12.207-6.171 1.00 0.00 ATOM 674 O GLU 160 5.261-13.121-6.906 1.00 0.00 ATOM 675 N LYS+ 161 5.656-11.194-5.806 1.00 0.00 ATOM 676 H LYS+ 161 5.293-10.528-5.188 1.00 0.00 ATOM 677 CA LYS+ 161 7.027-11. 063-6.239 1.00 0.00 ATOM 678 HA LYS+ 161 7.151-11.637-7.146 1.00 0.00 ATOM 679 CB LYS+ 161 7.370-9.591-6.501 1.00 0.00 ATOM 680 1HB LYS+ 161 7.740-9.155-5.586 1.00 0.00 ATOM 681 2HB LYS+ 161 6. 469-9.074-6.794 1.00 0.00 ATOM 682 QB LYS+ 161 7.105-9.114-6.190 1.00 0.00 ATOM 683 CG LYS+ 161 8.418-9.388-7.588 1.00 0.00 ATOM 684 1HG LYS+ 161 7.917-9.311-8.544 1.00 0.00 ATOM 685 2HG LYS+ 161 9.082-10.239-7.597 1.00 0.00 ATOM 686 QG LYS+ 161 8.500-9.775-8.070 1.00 0.00 ATOM 687 CD LYS+ 161 9.234-8.125-7.356 1.00 0.00 ATOM 688 1HD LYS+ 161 8.986-7.718-6.387 1.00 0.00 ATOM 689 2HD LYS+ 161 8.985-7.407-8.124 1.00 0. 00 ATOM 690 QD LYS+ 161 8.986-7.562-7.255 1.00 0.00 ATOM 691 CE LYS+ 161 10.728-8.406-7.415 1.00 0.00 ATOM 692 1HE LYS+ 161 11.236-7.508-7.737 1.00 0.00 ATOM 693 2HE LYS+ 161 10.904-9.193-8.134 1.00 0.00 ATOM 694 QE LYS+ 161 11.070-8.350-7.935 1.00 0.00 ATOM 695 NZ LYS+ 161 11.276-8.828-6.093 1.00 0.00 ATOM 696 1HZ LYS+ 161 12.250-8.478-5.980 1.00 0.00 ATOM 697 2HZ LYS+ 161 11.290-9.877-6.023 1.00 0.00 ATOM 698 3HZ LYS+ 161 10.692-8.452-5.319 1.00 0.00 ATOM 699 QZ LYS+ 161 11.411-8.935-5.774 1.00 0.00 ATOM 700 C LYS+ 161 7.927-11.633-5.153 1.00 0.00 ATOM 701 O LYS+ 161 7.632-12.671-4.570 1.00 0.00 ATOM 702 N SER 162 9.014-10.947-4.869 1.00 0.00 ATOM 703 H SER 162 9.197-10.122-5.350 1.00 0.00 ATOM 704 CA SER 162 9.929-11.391-3.840 1.00 0.00 ATOM 705 HA SER 162 9.522-12.295-3.410 1.00 0.00 ATOM 706 CB SER 162 11.300-11.703-4.441 1.00 0.00 ATOM 707 1HB SER 162 11.565-12.727-4.212 1.00 0.00 ATOM 708 2HB SER 162 12.037-11.037-4.012 1.00 0.00 ATOM 709 QB SER 162 11.801-11.882-4.112 1.00 0.00 ATOM 710 OG SER 162 11.289-11.533-5.857 1.00 0.00 ATOM 711 HG SER 162 11.139-12.392-6.275 1.00 0.00 ATOM 712 C SER 162 10.056-10.341-2.741 1.00 0.00 ATOM 713 O SER 162 11.161-9.937-2.393 1.00 0.00 ATOM 714 N THR 163 8.923-9.886-2.203 1.00 0.00 ATOM 715 H THR 163 8.060-10.231-2.527 1.00 0.00 ATOM 716 CA THR 163 8.938-8.888-1.134 1.00 0.00 ATOM 717 HA THR 163 9.868-9.009-0.591 1.00 0.00 ATOM 718 CB THR 163 8.877-7.454-1.677 1.00 0.00 ATOM 719 HB THR 163 8.762-6.786-0.828 1.00 0.00 ATOM 720 QG2 THR 163 10.410-6.918-2.612 1.00 0.00 ATOM 721 OG1 THR 163 7. 775-7.278-2.546 1.00 0.00 ATOM 722 1HG THR 163 7.572-6.341-2.626 1.00 0.00 ATOM 723 CG2 THR 163 10.115-7.021-2.433 1.00 0.00 ATOM 724 1HG2 THR 163 10.601-6.217-1.899 1.00 0. 00 ATOM 725 2HG2 THR 163 9.835-6.681-3.419 1.00 0.00 ATOM 726 3HG2 THR 163 10.794-7.857-2.518 1. 00 0. 00 ATOM 727 C THR 163 7.787-9. 111-0.152 1.00 0.00 ATOM 728 O THR 163 6.788-9.757-0.468 1.00 0.00 ATOM 729 N ASN 164 7.939-8.564 1.046 1.00 0.00 ATOM 730 H ASN 164 8.765-8.062 1.235 1.00 0. 00 ATOM 731 CA ASN 164 6.924-8.690 2.097 1.00 0.00 ATOM 732 HA ASN 164 6.051-9.160 1.660 1.00 0.00 ATOM 733 CB ASN 164 7.447-9.562 3.249 1.00 0.00 ATOM 734 1HB ASN 164 7.218-10.596 3.042 1.00 0.00 ATOM 735 2HB ASN 164 6.958-9.267 4.166 1.00 0.00 ATOM 736 QB ASN 164 7.088-9.931 3.604 1.00 0.00 ATOM 737 CG ASN 164 8.949-9.434 3.446 1.00 0. 00 ATOM 738 OD1 ASN 164 9.625-10.406 3.757 1.00 0.00 ATOM 739 ND2 ASN 164 9.470-8.224 3.287 1.00 0. 00 ATOM 740 1HD2 ASN 164 8.862-7.486 3.074 1.00 0.00

ATOM 741 2HD2 ASN 164 10.439-8.128 3.333 1.00 0.00 ATOM 742 QD2 ASN 164 9.651-7.807 3.204 1.00 0.00 ATOM 743 C ASN 164 6.535-7.318 2.644 1.00 0.00 ATOM 744 O ASN 164 7.399-6.484 2.906 1.00 0.00 ATOM 745 N LEU 165 5.238-7.088 2.810 1.00 0.00 ATOM 746 H LEU 165 4.598-7.792 2.584 1.00 0.00 ATOM 747 CA LEU 165 4.740-5.810 3.322 1.00 0.00 ATOM 748 HA LEU 165 5.243-5.013 2.794 1.00 0.00 ATOM 749 CB LEU 165 3.234-5.693 3.081 1.00 0.00 ATOM 750 1HB LEU 165 2.746-5.532 4.030 1.00 0.00 ATOM 751 2HB LEU 165 2.881-6.626 2.665 1.00 0.00 ATOM 752 QB LEU 165 2.814-6.079 3.348 1.00 0.00 ATOM 753 CG LEU 165 2.815-4.570 2.151 1.00 0.00 ATOM 754 HG LEU 165 3.369-3.676 2.397 1.00 0.00 ATOM 755 QD1 LEU 165 3.199-5.028 0.378 1.00 0.00 ATOM 756 QD2 LEU 165 0.984-4.205 2.366 1.00 0.00 ATOM 757 CD1 LEU 165 3.126-4.941 0.719 1.00 0.00 ATOM 758 1HD1 LEU 165 3.873-4.268 0.326 1.00 0.00 ATOM 759 2HD1 LEU 165 2.225-4.865 0.125 1.00 0.00 ATOM 760 3HD1 LEU 165 3.498-5.953 0.681 1.00 0.00 ATOM 761 CD2 LEU 165 1.335-4.275 2.325 1.00 0.00 ATOM 762 1HD2 LEU 165 0.756-5.116 1.972 1.00 0.00 ATOM 763 2HD2 LEU 165 1.075-3.395 1.755 1.00 0.00 ATOM 764 3HD2 LEU 165 1.121-4.104 3.370 1.00 0.00 ATOM 765 QQD LEU 165 2.091-4.617 1.372 1.00 0.00 ATOM 766 C LEU 165 5.020-5.651 4.805 1.00 0.00 ATOM 767 O LEU 165 4.648-6.501 5.612 1.00 0.00 ATOM 768 N HIS+ 166 5.664-4.549 5.148 1.00 0.00 ATOM 769 H HIS+ 166 5.925-3.910 4.451 1.00 0.00 ATOM 770 CA HIS+ 166 5.991-4.249 6.529 1.00 0.00 ATOM 771 HA HIS+ 166 5.677-5.086 7.136 1.00 0.00 ATOM 772 CB HIS+ 166 7.506-4.061 6.674 1.00 0.00 ATOM 773 1HB HIS+ 166 7.824-3.272 6.006 1.00 0.00 ATOM 774 2HB HIS+ 166 8.003-4.977 6.399 1.00 0.00 ATOM 775 QB HIS+ 166 7.914-4.124 6.203 1.00 0.00 ATOM 776 CG HIS+ 166 7.951-3.695 8.055 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.865-4.548 9.133 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.479-2.547 8.526 1.00 0.00 ATOM 779 1HD HIS+ 166 7.516-5.464 9.113 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.323-3.934 10.211 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.703-2.713 9.868 1.00 0.00 ATOM 782 2HD HIS+ 166 8.669-1.646 7.950 1.00 0.00 ATOM 783 1HE HIS+ 166 8.376-4.356 11.204 1.00 0.00 ATOM 784 2HE HIS+ 166 8.864-1.980 10.499 1.00 0.00 ATOM 785 C HIS+ 166 5.237-2.997 6.986 1.00 0.00 ATOM 786 O HIS+ 166 4.595-3.001 8.037 1.00 0.00 ATOM 787 N ASP 167 5.313-1.931 6.188 1.00 0.00 ATOM 788 H ASP 167 5.838-1.990 5.359 1.00 0.00 ATOM 789 CA ASP 167 4.637-0.674 6.525 1.00 0.00 ATOM 790 HA ASP 167 4.134-0.818 7.470 1.00 0.00 ATOM 791 CB ASP 167 5.639 0.483 6.672 1.00 0.00 ATOM 792 1HB ASP 167 5.260 1.181 7.405 1.00 0.00 ATOM 793 2HB ASP 167 5.729 0.988 5.722 1.00 0.00 ATOM 794 QB ASP 167 5.495 1.085 6.564 1.00 0.00 ATOM 795 CG ASP 167 7.022 0.044 7.104 1.00 0.00 ATOM 796 OD1 ASP 167 7.778-0.478 6.253 1.00 0.00 ATOM 797 OD2 ASP 167 7.356 0.226 8.293 1.00 0.00 ATOM 798 C ASP 167 3.598-0.293 5.473 1.00 0.00 ATOM 799 O ASP 167 3.907 0.379 4.492 1.00 0.00 ATOM 800 N TYR 168 2.366-0.720 5.686 1.00 0.00 ATOM 801 H TYR 168 2.181-1.245 6.491 1.00 0.00 ATOM 802 CA TYR 168 1.264-0.415 4.772 1.00 0.00 ATOM 803 HA TYR 168 1.676-0.237 3.781 1.00 0.00 ATOM 804 CB TYR 168 0.292-1.595 4.714 1.00 0.00 ATOM 805 1HB TYR 168 0.678-2.338 4.036 1.00 0.00 ATOM 806 2HB TYR 168-0.664-1.246 4.352 1.00 0.00 ATOM 807 QB TYR 168 0.007-1.792 4.194 1.00 0.00 ATOM 808 QD TYR 168 0.048-2.324 6.219 1. 00 o. oo ATOM 809 QE TYR 168-0.299-3.360 8.421 1.00 0.00 ATOM 810 QR TYR 168-0.126-2.842 7.320 1.00 0.00 ATOM 811 CG TYR 168 0.070-2.250 6.062 1.00 0.00 ATOM 812 CD1 TYR 168 0. 910-3.261 6.516 1.00 0.00

ATOM 813 1HD TYR 168 1.725-3.591 5.888 1.00 0.00 ATOM 814 CE1 TYR 168 0.719-3.845 7.753 1.00 0.00 ATOM 815 1HE TYR 168 1.383-4.629 8.088 1.00 0.00 ATOM 816 CZ TYR 168-0.321-3.422 8.554 1.00 0.00 ATOM 817 CE2 TYR 168-1.167-2.423 8.126 1.00 0.00 ATOM 818 2HE TYR 168-1.982-2.091 8.753 1.00 0.00 ATOM 819 CD2 TYR 168-0.969-1.842 6.888 1.00 0.00 ATOM 820 2HD TYR 168-1.630-1.058 6.550 1.00 0.00 ATOM 821 OH TYR 168-0.516-4.002 9.784 1.00 0.00 ATOM 822 HH TYR 168 0.153-3.685 10.399 1.00 0.00 ATOM 823 C TYR 168 0.518 0.835 5.223 1.00 0.00 ATOM 824 O TYR 168 0.429 1.119 6.417 1.00 0.00 ATOM 825 N GLY 169-0.038 1.556 4.269 1.00 0.00 ATOM 826 H GLY 169 0.051 1.269 3.335 1.00 0.00 ATOM 827 CA GLY 169-0. 791 2.752 4.576 1.00 0.00 ATOM 828 1HA GLY 169-0. 137 3.611 4.515 1.00 0.00 ATOM 829 2HA GLY 169-1.186 2.675 5.578 1.00 0.00 ATOM 830 QA GLY 169-0.661 3.143 5.047 1.00 0.00 ATOM 831 C GLY 169-1.925 2.929 3.602 1.00 0.00 ATOM 832 O GLY 169-1. 809 2.531 2.450 1.00 0.00 ATOM 833 N MET 170-3.023 3.506 4.046 1.00 0.00 ATOM 834 H MET 170-3.067 3.803 4.978 1.00 0.00 ATOM 835 CA MET 170-4.172 3.711 3.174 1.00 0.00 ATOM 836 HA MET 170-3.872 3.459 2.158 1.00 0.00 ATOM 837 CB MET 170-5.346 2.818 3.602 1.00 0.00 ATOM 838 1HB MET 170-6.267 3.345 3.395 1.00 0.00 ATOM 839 2HB MET 170-5.278 2.650 4.666 1.00 0. 00 ATOM 840 QB MET 170-5.772 2.998 4.031 1.00 0. 00 ATOM 841 CG MET 170-5.416 1.458 2.915 1.00 0.00 ATOM 842 1HG MET 170-5.773 1.605 1.905 1.00 0.00 ATOM 843 2HG MET 170-6.120 0.840 3.451 1.00 0.00 ATOM 844 QG MET 170-5.946 1.223 2.678 1.00 0.00 ATOM 845 SD MET 170-3.839 0.587 2.842 1.00 0.00 ATOM 846 QE MET 170-4.136-0.973 4.284 1.00 0.00 ATOM 847 CE MET 170-4.085-0.712 4.042 1.00 0.00 ATOM 848 1HE MET 170-4.634-1.523 3.587 1.00 0.00 ATOM 849 2HE MET 170-4.646-0.325 4.880 1.00 0.00 ATOM 850 3HE MET 170-3.127-1.072 4.385 1.00 0.00 ATOM 851 C MET 170-4.602 5.170 3.222 1.00 0.00 ATOM 852 O MET 170-4.920 5.694 4.291 1.00 0.00 ATOM 853 N LEU 171-4.607 5.824 2.072 1.00 0.00 ATOM 854 H LEU 171-4.341 5.355 1.252 1.00 0.00 ATOM 855 CA LEU 171-4.992 7.228 2.002 1.00 0.00 ATOM 856 HA LEU 171-5.139 7.577 3.013 1.00 0.00 ATOM 857 CB LEU 171-3.884 8.057 1.351 1.00 0.00 ATOM 858 1HB LEU 171-3.930 9.055 1.755 1.00 0.00 ATOM 859 2HB LEU 171-4. 082 8.111 0.287 1.00 0.00 ATOM 860 QB LEU 171-4.006 8.583 1.021 1.00 0. 00 ATOM 861 CG LEU 171-2.466 7.528 1.547 1.00 0.00 ATOM 862 HG LEU 171-2.488 6.693 2.233 1.00 0.00 ATOM 863 QD1 LEU 171-1.757 6.925-0.086 1.00 0.00 ATOM 864 QD2 LEU 171-1.372 8.863 2.287 1.00 0.00 ATOM 865 CD1 LEU 171-1.893 7.040 0.227 1.00 0.00 ATOM 866 1HD1 LEU 171-2.432 7.497-0.592 1.00 0.00 ATOM 867 2HD1 LEU 171-1.989 5.966 0.167 1.00 0.00 ATOM 868 3HD1 LEU 171-0.849 7.311 0.167 1.00 0.00 ATOM 869 CD2 LEU 171-1.582 8.608 2.145 1.00 0.00 ATOM 870 1HD2 LEU 171-1.336 9.333 1.384 1.00 0.00 ATOM 871 2HD2 LEU 171-0.674 8.158 2.523 1.00 0.00 ATOM 872 3HD2 LEU 171-2.105 9.096 2.953 1.00 0.00 ATOM 873 QQD LEU 171-1.564 7.894 1.101 1.00 0.00 ATOM 874 C LEU 171-6.289 7.413 1.227 1.00 0.00 ATOM 875 0 LEU 171-7.039 6. 453 1.022 1.00 0.00 ATOM 876 N LEU 172-6.529 8.661 0.805 1.00 0.00 ATOM 877 H LEU 172-5.867 9.354 1.013 1.00 0.00 ATOM 878 CA LEU 172-7.722 9.049 0.042 1.00 0.00 ATOM 879 HA LEU 172-7.853 10.112 0.167 1.00 0.00 ATOM 880 CB LEU 172-7.521 8.758-1.446 1.00 0.00 ATOM 881 1HB LEU 172-8.445 8.368-1.843 1.00 0.00 ATOM 882 2HB LEU 172-6.757 7.997-1.540 1.00 0.00 ATOM 883 QB LEU 172-7.601 8.183-1.691 1.00 0.00 ATOM 884 CG LEU 172-7.102 9.962-2.293 1.00 0.00

ATOM 885 HG LEU 172-6.090 10.242-2.030 1.00 0.00 ATOM 886 QD1 LEU 172-7. 120 9.516-4.116 1.00 0.00 ATOM 887 QD2 LEU 172-8.222 11.437-1.962 1.00 0.00 ATOM 888 CD1 LEU 172-7.118 9.601-3.766 1.00 0.00 ATOM 889 lHD1 LEU 172-7.281 8.540-3.876 1.00 0.00 ATOM 890 2HD1 LEU 172-6.169 9.867-4.210 1.00 0.00 ATOM 891 3HD1 LEU 172-7. 910 10.141-4.262 1.00 0.00 ATOM 892 CD2 LEU 172-8.009 11.154-2.025 1.00 0.00 ATOM 893 1HD2 LEU 172-7.853 11.901-2.790 1.00 0.00 ATOM 894 2HD2 LEU 172-7.773 11.574-1.059 1.00 0.00 ATOM 895 3HD2 LEU 172-9.040 10.834-2.039 1.00 0.00 ATOM 896 QQD LEU 172-7.671 10.476-3.039 1.00 0.00 ATOM 897 C LEU 172-8. 982 8.348 0.541 1.00 0.00 ATOM 898 O LEU 172-9.565 7.532-0.176 1.00 0.00 ATOM 899 N PRO 173-9.426 8.655 1.775 1.00 0.00 ATOM 900 CD PRO 173-8.804 9.622 2.700 1.00 0.00 ATOM 901 CA PRO 173-10.623 8.039 2.351 1.00 0.00 ATOM 902 HA PRO 173-10.443 7.002 2.605 1.00 0.00 ATOM 903 CB PRO 173-10.872 8.849 3.623 1. 00 0.00 ATOM 904 1HB PRO 173-11.265 8.202 4.394 1.00 0.00 ATOM 905 2HB PRO 173-11.578 9.641 3.415 1.00 0.00 ATOM 906 QB PRO 173-11.421 8.922 3.905 1.00 0.00 ATOM 907 CG PRO 173-9.535 9.390 3.996 1.00 0.00 ATOM 908 1HG PRO 173-9.004 8.670 4.602 1.00 0.00 ATOM 909 2HG PRO 173-9.652 10.320 4.533 1.00 0.00 ATOM 910 QG PRO 173-9.328 9.495 4.568 1.00 0.00 ATOM 911 1HD PRO 173-7.750 9.416 2.819 1.00 0.00 ATOM 912 2HD PRO 173-8.956 10.635 2.358 1.00 0.00 ATOM 913 QD PRO 173-8.353 10.026 2.589 1.00 0.00 ATOM 914 C PRO 173-11.820 8.124 1.414 1.00 0.00 ATOM 915 O PRO 173-12.050 9.147 0.764 1.00 0.00 ATOM 916 N CYS 174-12.565 7.039 1.333 1.00 0.00 ATOM 917 H CYS 174-12.321 6.252 1.870 1.00 0.00 ATOM 918 CA CYS 174-13.729 6.973 0.467 1.00 0.00 ATOM 919 HA CYS 174-13.765 7.885-0.109 1.00 0.00 ATOM 920 CB CYS 174-13.597 5.785-0.486 1.00 0.00 ATOM 921 1HB CYS 174-13.196 4.942 0.058 1.00 0.00 ATOM 922 2HB CYS 174-12.915 6.048-1.281 1.00 0.00 ATOM 923 QB CYS 174-13.055 5.495-0.611 1.00 0.00 ATOM 924 SG CYS 174-15.155 5.252-1.258 1.00 0.00 ATOM 925 C CYS 174-15.000 6.867 1.296 1.00 0.00 ATOM 926 O CYS 174-16.027 7.449 0.956 1.00 0.00 ATOM 927 N GLY 175-14.913 6.138 2.397 1.00 0.00 ATOM 928 H GLY 175-14.059 5.712 2.627 1.00 0.00 ATOM 929 CA GLY 175-16.050 5.981 3.279 1.00 0.00 ATOM 930 1HA GLY 175-16.531 5.037 3.072 1.00 0.00 ATOM 931 2HA GLY 175-16.751 6.783 3.100 1.00 0.00 ATOM 932 QA GLY 175-16.641 5.910 3.086 1.00 0.00 ATOM 933 C GLY 175-15.622 6.011 4. 724 1.00 0. 00 ATOM 934 O GLY 175-14.563 6.547 5.043 1.00 0.00 ATOM 935 N ILE 176-16.428 5.427 5.597 1.00 0.00 ATOM 936 H ILE 176-17.253 5.006 5.283 1.00 0.00 ATOM 937 CA ILE 176-16.101 5.383 7.015 1.00 0.00 ATOM 938 HA ILE 176-15.772 6.368 7.316 1.00 0.00 ATOM 939 CB ILE 176-17.329 4.989 7.867 1.00 0.00 ATOM 940 HB ILE 176-17.441 3.917 7.815 1.00 0. 00 ATOM 941 QG2 ILE 176-17.066 5.463 9.670 1.00 0.00 ATOM 942 CG2 ILE 176-17.116 5.371 9.325 1.00 0.00 ATOM 943 1HG2 ILE 176-16.063 5.325 9.560 1.00 0.00 ATOM 944 2HG2 ILE 176-17.657 4.686 9.960 1.00 0.00 ATOM 945 3HG2 ILE 176-17. 478 6.376 9.489 1.00 0. 00 ATOM 946 CG1 ILE 176-18. 601 5.651 7.324 1.00 0. 00 ATOM 947 1HG1 ILE 176-19.463 5.165 7.757 1.00 0.00 ATOM 948 2HG1 ILE 176-18.630 5.536 6.252 1.00 0.00 ATOM 949 QG1 ILE 176-19.046 5.351 7.005 1.00 0. 00 ATOM 950 QD1 ILE 176-18.718 7.482 7.709 1.00 0. 00 ATOM 951 CD1 ILE 176-18.696 7.131 7.634 1.00 0.00 ATOM 952 1HD1 ILE 176-18.582 7.698 6.723 1. 00 0.00 ATOM 953 2HD1 ILE 176-17.913 7'. 402 8.328 1. oo 0.00 ATOM 954 3HD1 ILE 176-19. 658 7.345 8.076 1.00 0.00 ATOM 955 C ILE 176-14.972 4.382 7.259 1.00 0. 00 ATOM 956 O ILE 176-14.162 4.542 8.172 1. oo 0. 00

ATOM 957 N ASP 177-14.937 3.345 6.428 1.00 0.00 ATOM 958 H ASP 177-15.617 3.278 5.728 1.00 0.00 ATOM 959 CA ASP 177-13.927 2.297 6. 530 1.00 0.00 ATOM 960 HA ASP 177-13.210 2.584 7.283 1.00 0.00 ATOM 961 CB ASP 177-14.596 0.980 6.941 1.00 0.00 ATOM 962 1HB ASP 177-15.277 1.168 7.758 1.00 0.00 ATOM 963 2HB ASP 177-13.837 0.283 7.263 1.00 0.00 ATOM 964 QB ASP 177-14.557 0.726 7.511 1.00 0.00 ATOM 965 CG ASP 177-15.374 0.350 5.799 1.00 0.00 ATOM 966 OD1 ASP 177-15.058-0.796 5.420 1.00 0.00 ATOM 967 OD2 ASP 177-16.291 1.007 5.262 1.00 0.00 ATOM 968 C ASP 177-13.211 2.082 5.197 1.00 0.00 ATOM 969 O ASP 177-12.250 1.312 5. 111 1.00 0.00 ATOM 970 N LYS+ 178-13.709 2.727 4.152 1.00 0.00 ATOM 971 H LYS+ 178-14.491 3.300 4.276 1.00 0.00 ATOM 972 CA LYS+ 178-13.144 2.567 2.818 1.00 0.00 ATOM 973 HA LYS+ 178-12.605 1.632 2.802 1.00 0.00 ATOM 974 CB LYS+ 178-14.269 2.500 1.785 1.00 0.00 ATOM 975 1HB LYS+ 178-13.853 2.195 0.837 1.00 0.00 ATOM 976 2HB LYS+ 178-14.701 3.484 1.677 1.00 0.00 ATOM 977 QB LYS+ 178-14.277 2.840 1.257 1.00 0.00 ATOM 978 CG LYS+ 178-15.383 1.527 2.156 1.00 0. 00 ATOM 979 1HG LYS+ 178-16.313 2.072 2.225 1.00 0.00 ATOM 980 2HG LYS+ 178-15.154 1.083 3.114 1.00 0.00 ATOM 981 QG LYS+ 178-15.733 1.578 2.670 1.00 0.00 ATOM 982 CD LYS+ 178-15.534 0.418 1.123 1.00 0.00 ATOM 983 1HD LYS+ 178-14. 693 0.453 0.444 1.00 0.00 ATOM 984 2HD LYS+ 178-16.448 0.577 0.568 1.00 0.00 ATOM 985 QD LYS+ 178-15.570 0.515 0.506 1.00 0.00 ATOM 986 CE LYS+ 178-15. 586-0.959 1.773 1.00 0.00 ATOM 987 1HE LYS+ 178-14.575-1.291 1.966 1.00 0.00 ATOM 988 2HE LYS+ 178-16.063-1.648 1.091 1.00 0.00 ATOM 989 QE LYS+ 178-15.319-1.469 1.529 1.00 0.00 ATOM 990 NZ LYS+ 178-16.344-0.943 3.057 1.00 0.00 ATOM 991 1HZ LYS+ 178-17.002-0.142 3.080 1.00 0.00 ATOM 992 2HZ LYS+ 178-15.685-0.851 3.868 1.00 0.00 ATOM 993 3HZ LYS+ 178-16.880-1.825 3.167 1.00 0.00 ATOM 994 QZ LYS+ 178-16.522-0.939 3.372 1.00 0.00 ATOM 995 C LYS+ 178-12.164 3.671 2.462 1.00 0.00 ATOM 996 O LYS+ 178-12.282 4.804 2.926 1.00 0.00 ATOM 997 N PHE 179-11.197 3.322 1.620 1.00 0.00 ATOM 998 H PHE 179-11.174 2.400 1.276 1.00 0.00 ATOM 999 CA PHE 179-10.175 4.254 1.177 1.00 0.00 ATOM 1000 HA PHE 179-10.501 5.256 1.407 1.00 0.00 ATOM 1001 CB PHE 179-8.847 3.976 1.880 1.00 0.00 ATOM 1002 1HB PHE 179-8. 110 4.635 1.474 1.00 0.00 ATOM 1003 2HB PHE 179-8.543 2.964 1.677 1.00 0.00 ATOM 1004 QB PHE 179-8.326 3.800 1.576 1.00 0.00 ATOM 1005 QD PHE 179-8.877 4.191 3.537 1.00 0.'00 ATOM 1006 QE PHE 179-8.923 4.513 5.974 1.00 0.00 ATOM 1007 QR PHE 179-8.909 4.416 5. 244 1.00 0.00 ATOM 1008 CG PHE 179-8.874 4.169 3.371 1.00 0.00 ATOM 1009 CD1 PHE 179-9.360 3.175 4.207 1.00 0.00 ATOM 1010 1HD PHE 179-9.722 2.252 3.778 1.00 0.00 ATOM 1011 CE1 PHE 179-9.386 3.353 5.576 1.00 0.00 ATOM 1012 1HE PHE 179-9.770 2.571 6.215 1.00 0.00 ATOM 1013 CZ PHE 179-8.925 4.532 6. 127 1.00 0.00 ATOM 1014 HZ PHE 179-8.945 4.675 7.198 1.00 0.00 ATOM 1015 CE2 PHE 179-8.437 5.530 5.306 1.00 0.00 ATOM 1016 2HE PHE 179-8.076 6.454 5.733 1.00 0.00 ATOM 1017 CD2 PHE 179-8.415 5.347 3.936 1.00 0.00 ATOM 1018 2HD PHE 179-8.032 6.129 3.295 1.00 0.00 ATOM 1019 C PHE 179-9.957 4.120-0.316 1.00 0.00 ATOM 1020 O PHE 179-10.643 3.346-0.984 1.00 0.00 ATOM 1021 N ARG+ 180-8.979 4.855-0.824 1.00 0.00 ATOM 1022 H ARG+ 180-8.462 5.438-0.223 1.00 0.00 ATOM 1023 CA ARG+ 180-8.633 4.808-2.240 1.00 0.00 ATOM 1024 HA ARG+ 180-9. 014 3.880-2.645 1.00 0.00 ATOM 1025 CB ARG+ 180-9.264 5.977-3.004 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.990 5.890-4.047 1.00 0. 00 ATOM 1027 2HB ARG+ 180-8.868 6.903-2.617 1.00 0.00 ATOM 1028 QB ARG+ 180-8.929 6.397-3.332 1.00 0.00

ATOM 1029 CG ARG+ 180-10.781 6.026-2.914 1.00 0.00 ATOM 1030 1HG ARG+ 180-11.071 5.956-1.877 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.188 5.187-3.462 1.00 0.00 ATOM 1032 QG ARG+ 180-11.129 5.572-2.669 1.00 0.00 ATOM 1033 CD ARG+ 180-11. 335 7.313-3.500 1.00 0.00 ATOM 1034 1HD ARG+ 180-12.259 7.088-4.014 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.619 7.710-4.206 1.00 0.00 ATOM 1036 QD ARG+ 180-11.439 7.399-4.110 1.00 0.00 ATOM 1037 NE ARG+ 180-11.595 8.318-2.470 1.00 0.00 ATOM 1038 HE ARG+ 180-11.183 8.177-1.584 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.355 9.396-2.665 1.00 0.00 ATOM 1040 NH1 ARG+ 180-12.896 9.619-3.859 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.731 8.979-4.612 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.466 10.427-4.012 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.098 9.703-4.312 1.00 0.00 ATOM 1044 NH2 ARG+ 180-12.572 10.245-1.668 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.165 10.075-0.762 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.141 11.056-1.810 1.00 0.00 ATOM 1047 QH2 ARG+ 180-12.653 10.566-1.286 1.00 0.00 ATOM 1048 C ARG+ 180-7.116 4.836-2.428 1.00 0.00 ATOM 1049 O ARG+ 180-6.618 4.571-3.511 1.00 0.00 ATOM 1050 N GLY 181-6.380 5.162-1.378 1.00 0.00 ATOM 1051 H GLY 181-6.811 5.367-0.521 1.00 0.00 ATOM 1052 CA GLY 181-4.935 5.223-1.499 1.00 0.00 ATOM 1053 1HA GLY 181-4.593 6.176-1.119 1.00 0.00 ATOM 1054 2HA GLY 181-4.674 5.154-2.544 1.00 0.00 ATOM 1055 QA GLY 181-4.633 5.665-1.831 1.00 0.00 ATOM 1056 C GLY 181-4.230 4.117-0.751 1.00 0.00 ATOM 1057 O GLY 181-4.775 3.560 0.202 1.00 0.00 ATOM 1058 N VAL 182-3.013 3.798-1.185 1.00 0.00 ATOM 1059 H VAL 182-2.641 4.286-1.945 1.00 0.00 ATOM 1060 CA VAL 182-2. 211 2.750-0.561 1.00 0.00 ATOM 1061 HA VAL 182-2.530 2.654 0.468 1.00 0.00 ATOM 1062 CB VAL 182-2.378 1.374-1.262 1.00 0.00 ATOM 1063 HB VAL 182-1.583 1.274-1.988 1.00 0.00 ATOM 1064 QG1 VAL 182-2.202-0.024-0.019 1.00 0.00 ATOM 1065 QG2 VAL 182-4.022 1.232-2.171 1.00 0.00 ATOM 1066 CG1 VAL 182-2.235 0.243-0.257 1.00 0.00 ATOM 1067 1HG1 VAL 182-1.271-0.229-0.380 1.00 0.00 ATOM 1068 2HG1 VAL 182-3.016-0.484-0.424 1.00 0.00 ATOM 1069 3HG1 VAL 182-2.319 0.639 0.745 1.00 0.00 ATOM 1070 CG2 VAL 182-3.707 1.259-1.998 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.641 1.775-2.945 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.490 1.704-1.400 1.00 0.00 ATOM 1073 3HG2 VAL 182-3.935 0.217-2.170 1.00 0.00 ATOM 1074 QQG VAL 182-3.112 0.604-1.095 1.00 0. 00 ATOM 1075 C VAL 182-0.724 3.123-0.578 1.00 0.00 ATOM 1076 O VAL 182-0.176 3.484-1.618 1.00 0.00 ATOM 1077 N GLU 183-0.087 3.023 0.584 1.00 0. 00 ATOM 1078 H GLU 183-0. 596 2.728 1.373 1.00 0.00 ATOM 1079 CA GLU 183 1.333 3.330 0.744 1.00 0.00 ATOM 1080 HA GLU 183 1.779 3.407-0.238 1.00 0.00 ATOM 1081 CB GLU 183 1.515 4.655 1.495 1.00 0.00 ATOM 1082 1HB GLU 183 1.872 5.403 0.801 1.00 0.00 ATOM 1083 2HB GLU 183 2.257 4.515 2.268 1.00 0.00 ATOM 1084 QB GLU 183 2.065 4.959 1.535 1.00 0.00 ATOM 1085 CG GLU 183 0.248 5.182 2.151 1.00 0.00 ATOM 1086 1HG GLU 183-0.364 4.341 2.445 1.00 0.00 ATOM 1087 2HG GLU 183-0. 290 5.783 1.434 1.00 0.00 ATOM 1088 QG GLU 183-0.327 5.062 1.940 1.00 0.00 ATOM 1089 CD GLU 183 0.524 6.030 3.376 1.00 0.00 ATOM 1090 OE1 GLU 183 0.081 5.645 4.474 1.00 0.00 ATOM 1091 OE2 GLU 183 1.176 7.087 3.236 1.00 0.00 ATOM 1092 C GLU 183 2.016 2.212 1.528 1.00 0.00 ATOM 1093 O GLU 183 2.082 2.258 2.750 1.00 0.00 ATOM 1094 N PHE 184 2.492 1.192 0.839 1.00 0.00 ATOM 1095 H PHE 184 2.394 1.183-0.131 1.00 0.00 ATOM 1096 CA PHE 184 3.121 0.061 1.512 1.00 0.00 ATOM 1097 HA PHE 184 3.005 0.220 2.572 1.00 0.00 ATOM 1098 CB PHE 184 2.424-1.252 1.141 1.00 0.00 ATOM 1099 1HB PHE 184 1.533-1.362 1.742 1.00 0. 00 ATOM 1100 2HB PHE 184 3.093-2.071 1.366 1.00 0. 00

ATOM 1101 QB PHE 184 2.313-1.716 1.554 1.00 0.00 ATOM 1102 QD PHE 184 1.982-1.393-0.478 1.00 0.00 ATOM 1103 QE PHE 184 1.310-1.662-2.826 1.00 0.00 ATOM 1104 QR PHE 184 1.510-1.584-2.122 1.00 0.00 ATOM 1105 CG PHE 184 2.029-1.379-0.313 1.00 0.00 ATOM 1106 CD1 PHE 184 2.633-2.326-1.121 1.00 0.00 ATOM 1107 1HD PHE 184 3.409-2.954-0.711 1.00 0.00 ATOM 1108 CE1 PHE 184 2.254-2.482-2.439 1.00 0.00 ATOM 1109 1HE PHE 184 2.737-3.226-3.055 1.00 0.00 ATOM 1110 CZ PHE 184 1.266-1.683-2.971 1.00 0.00 ATOM 1111 HZ PHE 184 0.965-1.810-4.000 1.00 0.00 ATOM 1112 CE2 PHE 184 0.657-0.728-2.184 1.00 0.00 ATOM 1113 2HE PHE 184-0. 118-0. 099-2.598 1.00 0.00 ATOM 1114 CD2 PHE 184 1.033-0.582-0.861 1.00 0.00 ATOM 1115 2HD PHE 184 0.555 0.167-0.246 1.00 0.00 ATOM 1116 C PHE 184 4.604-0.067 1.209 1.00 0.00 ATOM 1117 O PHE 184 5.044 0.140 0.084 1.00 0.00 ATOM 1118 N VAL 185 5.365-0.438 2.228 1.00 0.00 ATOM 1119 H VAL 185 4.947-0.601 3.100 1.00 0.00 ATOM 1120 CA VAL 185 6.798-0.629 2.092 1.00 0.00 ATOM 1121 HA VAL 185 7.089-0.327 1.095 1.00 0.00 ATOM 1122 CB VAL 185 7.586 0.220 3.119 1.00 0.00 ATOM 1123 HB VAL 185 7.781-0.392 3.993 1.00 0.00 ATOM 1124 QG1 VAL 185 9.230 0.764 2.403 1.00 0.00 ATOM 1125 QG2 VAL 185 6.598 1.724 3.669 1.00 0.00 ATOM 1126 CG1 VAL 185 8.915 0.659 2.540 1.00 0.00 ATOM 1127 1HG1 VAL 185 8.877 1.714 2.314 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.115 0.104 1.635 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.698 0.473 3.259 1.00 0.00 ATOM 1130 CG2 VAL 185 6.788 1.436 3.562 1.00 0.00 ATOM 1131 1HG2 VAL 185 6.887 2.221 2.828 1.00 0.00 ATOM 1132 2HG2 VAL 185 7.162 1.783 4.515 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.746 1.166 3.664 1.00 0.00 ATOM 1134 QQG VAL 185 7.914 1.244 3.036 1.00 0.00 ATOM 1135 C VAL 185 7.128-2.112 2.275 1.00 0.00 ATOM 1136 O VAL 185 7.047-2.648 3.379 1.00 0.00 ATOM 1137 N CYS 186 7.476-2.783 1.184 1.00 0.00 ATOM 1138 H CYS 186 7.509-2.313 0.319 1.00 0.00 ATOM 1139 CA CYS 186 7.796-4.206 1.239 1.00 0.00 ATOM 1140 HA CYS 186 7.607-4.542 2.250 1.00 0.00 ATOM 1141 CB CYS 186 6.896-5.007 0.288 1.00 0.00 ATOM 1142 1HB CYS 186 5.875-4.939 0.637 1.00 0.00 ATOM 1143 2HB CYS 186 7.204-6.041 0.310 1.00 0.00 ATOM 1144 QB CYS 186 6.540-5.490 0.474 1.00 0.00 ATOM 1145 SG CYS 186 6.923-4.471-1.452 1.00 0.00 ATOM 1146 C CYS 186 9.269-4.449 0.925 1.00 0.00 ATOM 1147 O CYS 186 9.790-3.947-0.063 1.00 0.00 ATOM 1148 N CYS 187 9.942-5.218 1.774 1.00 0.00 ATOM 1149 H CYS 187 9.476-5.595 2.551 1.00 0.00 ATOM 1150 CA CYS 187 11.365-5.505 1.580 1.00 0.00 ATOM 1151 HA CYS 187 11.788-4.695 1.007 1.00 0.00 ATOM 1152 CB CYS 187 12.090-5.594 2.926 1.00 0.00 ATOM 1153 1HB CYS 187 12.907-6.297 2.838 1.00 0.00 ATOM 1154 2HB CYS 187 11.400-5.946 3.678 1.00 0.00 ATOM 1155 QB CYS 187 12.154-6.121 3.258 1.00 0.00 ATOM 1156 SG CYS 187 12.780-4.012 3.502 1.00 0.00 ATOM 1157 C CYS 187 11.564-6.798 0.814 1.00 0.00 ATOM 1158 O CYS 187 10.710-7.676 0.853 1.00 0.00 ATOM 1159 N PRO 188 12.694-6.926 0.100 1.00 0.00 ATOM 1160 CD PRO 188 13.763-5.910-0.004 1.00 0.00 ATOM 1161 CA PRO 188 12.996-8.126-0.683 1.00 0.00 ATOM 1162 HA PRO 188 12.206-8.343-1.386 1.00 0.00 ATOM 1163 CB PRO 188 14.272-7.756-1.447 1.00 0.00 ATOM 1164 1HB PRO 188 14.017-7.437-2.445 1.00 0.00 ATOM 1165 2HB PRO 188 14.923-8.618-1.495 1.00 0.00 ATOM 1166 QB PRO 188 14.470-8.027-1.970 1.00 0.00 ATOM 1167 CG PRO 188 14.894-6.650-0.663 1.00 0.00 ATOM 1168 1HG PRO 188 15.437-5.991-1.325 1.00 0.00 ATOM 1169 2HG PRO 188 15.557-7.060 0.085 1.00 0.00 ATOM 1170 QG PRO 188 15.497-6.525-0.620 1.00 0.00 ATOM 1171 1HD PRO 188 13.448-5.076-0.615 1.00 0.00 ATOM 1172 2HD PRO 188 14.063-5.564 0.976 1.00 0.00

ATOM 1173 QD PRO 188 13.756-5.320 0.181 1.00 0.00 ATOM 1174 C PRO 188 13.234-9.355 0.193 1.00 0.00 ATOM 1175 0 PRO 188 14.035-9.317 1.130 1.00 0.00 ATOM 1176 N LEU 189 12.531-10.431-0.131 1.00 0.00 ATOM 1177 H LEU 189 11.915-10.383-0.893 1.00 0.00 ATOM 1178 CA LEU 189 12.644-11.687 0.592 1.00 0.00 ATOM 1179 HA LEU 189 13.522-11.636 1.219 1.00 0.00 ATOM 1180 CB LEU 189 11.405-11.917 1.465 1.00 0.00 ATOM 1181 1HB LEU 189 10.676-12.451 0.873 1.00 0.00 ATOM 1182 2HB LEU 189 10.993-10.954 1.727 1.00 0.00 ATOM 1183 QB LEU 189 10.835-11.702 1.300 1.00 0.00 ATOM 1184 CG LEU 189 11.639-12.708 2.759 1.00 0.00 ATOM 1185 HG LEU 189 10.931-12.376 3.505 1.00 0.00 ATOM 1186 QD1 LEU 189 11.362-14.543 2.473 1.00 0.00 ATOM 1187 QD2 LEU 189 13.372-12.402 3.425 1.00 0.00 ATOM 1188 CD1 LEU 189 11.414-14.192 2.528 1.00 0.00 ATOM 1189 1HD1 LEU 189 11.893-14.487 1.605 1.00 0.00 ATOM 1190 2HD1 LEU 189 10.355-14.390 2.464 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.837-14.752 3.348 1.00 0.00 ATOM 1192 CD2 LEU 189 13.040-12.461 3.298 1.00 0.00 ATOM 1193 1HD2 LEU 189 13.109-12.835 4.308 1.00 0.00 ATOM 1194 2HD2 LEU 189 13.247-11.401 3.291 1.00 0.00 ATOM 1195 3HD2 LEU 189 13.759-12.972 2.674 1.00 0.00 ATOM 1196 QQD LEU 189 12.367-13.473 2.949 1.00 0.00 ATOM 1197 C LEU 189 12.803-12.833-0.402 1.00 0.00 ATOM 1198 OT1 LEU 189 13.593-13.757-0.125 1.00 0.00 ATOM 1199 OT2 LEU 189 12.137-12.788-1.461 1.00 0.00 TER ENDMDL MODEL 13 ATOM I N SER 124 14.743 16.882-1.442 1.00 0.00 ATOM 2 CA SER 124 14.927 16.212-0.130 1.00 0.00 ATOM 3 HA SER 124 15.675 15.440-0.230 1.00 0.00 ATOM 4 CB SER 124 15.404 17.264 0.869 1.00 0.00 ATOM 5 1HB SER 124 16.210 16.857 1.462 1.00 0.00 ATOM 6 2HB SER 124 14.582 17.539 1.515 1.00 0.00 ATOM 7 QB SER 124 15.396 17.198 1.489 1.00 0.00 ATOM 8 OG SER 124 15.869 18.425 0.192 1.00 0.00 ATOM 9 HG SER 124 16.030 19.128 0.831 1.00 0.00 ATOM 10 C SER 124 13.618 15.594 0.326 1.00 0.00 ATOM 11 O SER 124 13.240 15.682 1.494 1.00 0.00 ATOM 12 1HT SER 124 15.004 17.886-1.365 1.00 0.00 ATOM 13 2HT SER 124 13.743 16.816-1.741 1.00 0.00 ATOM 14 3HT SER 124 15.338 16.432-2.163 1.00 0.00 ATOM 15 N ASP 125 12.925 15.000-0.626 1.00 0.00 ATOM 16 H ASP 125 13.280 14.995-1.540 1.00 0.00 ATOM 17 CA ASP 125 11.634 14.389-0.391 1.00 0.00 ATOM 18 HA ASP 125 11.277 14.714 0.575 1.00 0.00 ATOM 19 CB ASP 125 10.655 14.856-1.473 1.00 0.00 ATOM 20 1HB ASP 125 9.684 15.017-1.028 1.00 0.00 ATOM 21 2HB ASP 125 10.577 14.093-2.233 1.00 0. 00 ATOM 22 QB ASP 125 10.130 14. 555-1. 630 1.00 0.00 ATOM 23 CG ASP 125 11.102 16.152-2.134 1.00 0.00 ATOM 24 OD1 ASP 125 10.432 17.179-1.932 1.00 0.00 ATOM 25 OD2 ASP 125 12.145 16.145-2.835 1.00 0.00 ATOM 26 C ASP 125 11.746 12.873-0.403 1.00 0.00 ATOM 27 O ASP 125 12.639 12.314-1.041 1.00 0.00 ATOM 28 N ALA 126 10.838 12.212 0.301 1.00 0.00 ATOM 29 H ALA 126 10.150 12.716 0.784 1.00 0.00 ATOM 30 CA ALA 126 10.832 10.757 0.370 1.00 0.00 ATOM 31 HA ALA 126 11.359 10.379-0.494 1.00 0.00 ATOM 32 QB ALA 126 11.730 10.166 1.916 1.00 0.00 ATOM 33 CB ALA 126 11.559 10.280 1.620 1.00 0.00 ATOM 34 1HB ALA 126 12.117 11.099 2.048 1.00 0.00 ATOM 35 2HB ALA 126 12.237 9.480 1.359 1.00 0.00 ATOM 36 3HB ALA 126 10.837 9.920 2.340 1.00 0.00 ATOM 37 C ALA 126 9.406 10.226 0.356 1.00 0.00 ATOM 38 O ALA 126 8.727 10.224 1.381 1.00 0.00 ATOM 39 N LEU 127 8.955 9. 785-0. 809 1. 00 0. 00 ATOM 40 H LEU 127 9.539 9.817-1.591 1.00 0.00 ATOM 41 CA LEU 127 7.605 9.257-0.953 1.00 0.00 ATOM 42 HA LEU 127 7.167 9.199 0. 030 1.00 0.00

ATOM 43 CB LEU 127 6.764 10.193-1.824 1.00 0.00 ATOM 44 1HB LEU 127 6.900 9.904-2.856 1.00 0.00 ATOM 45 2HB LEU 127 7.135 11.200-1.697 1.00 0.00 ATOM 46 QB LEU 127 7.017 10.552-2.276 1.00 0.00 ATOM 47 CG LEU 127 5.265 10.191-1.521 1.00 0.00 ATOM 48 HG LEU 127 4.997 9.247-1.066 1.00 0.00 ATOM 49 QD1 LEU 127 4.830 11.562-0.313 1.00 0.00 ATOM 50 QD2 LEU 127 4.275 10.372-3.108 1.00 0.00 ATOM 51 CD1 LEU 127 4.914 11.299-0.544 1.00 0.00 ATOM 52 1HD1 LEU 127 4.694 10.870 0. 422 1.00 0.00 ATOM 53 2HD1 LEU 127 4.048 11.835-0.905 1.00 0.00 ATOM 54 3HD1 LEU 127 5.747 11.980-0.456 1.00 0.00 ATOM 55 CD2 LEU 127 4.465 10.337-2.805 1.00 0.00 ATOM 56 1HD2 LEU 127 3.425 10.498-2.563 1.00 0.00 ATOM 57 2HD2 LEU 127 4.563 9.438-3.395 1.00 0.00 ATOM 58 3HD2 LEU 127 4.838 11.180-3.367 1.00 0.00 ATOM 59 QQD LEU 127 4.552 10.967-1.710 1.00 0.00 ATOM 60 C LEU 127 7.634 7.864-1.570 1.00 0.00 ATOM 61 O LEU 127 6.601 7.328-1.972 1.00 0.00 ATOM 62 N LEU 128 8.821 7.283-1.649 1.00 0.00 ATOM 63 H LEU 128 9.609 7.754-1.315 1.00 0.00 ATOM 64 CA LEU 128 8.978 5.959-2.221 1.00 0.00 ATOM 65 HA LEU 128 8.022 5.460-2.172 1.00 0.00 ATOM 66 CB LEU 128 9.412 6.067-3.687 1.00 0.00 ATOM 67 1HB LEU 128 10.492 6.063-3.719 1.00 0.00 ATOM 68 2HB LEU 128 9.062 7.013-4.074 1.00 0.00 ATOM 69 QB LEU 128 9.777 6.538-3.896 1.00 0.00 ATOM 70 CG LEU 128 8.901 4.953-4.604 1.00 0.00 ATOM 71 HG LEU 128 8.646 4.088-4.007 1.00 0.00 ATOM 72 QD1 LEU 128 7.350 5.507-5.507 1.00 0.00 ATOM 73 QD2 LEU 128 10.230 4.448-5.833 1.00 0.00 ATOM 74 CD1 LEU 128 7.647 5.401-5.334 1.00 0.00 ATOM 75 1HD1 LEU 128 7.081 6.069-4.702 1.00 0.00 ATOM 76 2HD1 LEU 128 7.045 4.538-5.577 1.00 0.00 ATOM 77 3HD1 LEU 128 7.924 5.914-6.244 1.00 0.00 ATOM 78 CD2 LEU 128 9.976 4.544-5.598 1.00 0.00 ATOM 79 1HD2 LEU 128 10.669 5.362-5.735 1.00 0.00 ATOM 80 2HD2 LEU 128 9.516 4.301-6.544 1.00 0.00 ATOM 81 3HD2 LEU 128 10.506 3.682-5.222 1.00 0.00 ATOM 82 QQD LEU 128 8.790 4.978-5.670 1.00 0.00 ATOM 83 C LEU 128 9.992 5.158-1.416 1.00 0.00 ATOM 84 O LEU 128 10.152 5.389-0.219 1.00 0.00 ATOM 85 N VAL 129 10.655 4.216-2.084 1.00 0. 00 ATOM 86 H VAL 129 10.457 4.098-3.035 1.00 0.00 ATOM 87 CA VAL 129 11.659 3.346-1.464 1.00 0.00 ATOM 88 HA VAL 129 11.142 2.620-0.857 1.00 0.00 ATOM 89 CB VAL 129 12.465 2.587-2.544 1.00 0.00 ATOM 90 HB VAL 129 13.075 3.307-3.072 1.00 0.00 ATOM 91 QG1 VAL 129 13.616 1.319-1.763 1.00 0.00 ATOM 92 QG2 VAL 129 11.321 1.765-3.790 1.00 0.00 ATOM 93 CG1 VAL 129 13.395 1.561-1.913 1.00 0.00 ATOM 94 1HG1 VAL 129 13.686 0.834-2.656 1.00 0.00 ATOM 95 2HG1 VAL 129 12.886 1.063-1.100 1.00 0.00 ATOM 96 3HG1 VAL 129 14.275 2.061-1.534 1.00 0.00 ATOM 97 CG2 VAL 129 11.539 1.922-3.551 1.00 0.00 ATOM 98 1HG2 VAL 129 11.742 2.314-4.537 1.00 0.00 ATOM 99 2HG2 VAL 129 10.512 2.124-3.287 1.00 0.00 ATOM 100 3HG2 VAL 129 11.710 0.856-3.546 1.00 0.00 ATOM 101 QQG VAL 129 12.468 1.542-2.776 1.00 0.00 ATOM 102 C VAL 129 12.644 4.119-0. 582 1.00 0.00 ATOM 103 O VAL 129 13.460 4.889-1. 085 1.00 0.00 ATOM 104 N PRO 130 12.581 3.913 0.749 1.00 0.00 ATOM 105 CD PRO 130 11.644 3.025 1.437 1.00 0.00 ATOM 106 CA PRO 130 13.473 4.574 1.694 1.00 0.00 ATOM 107 HA PRO 130 13.596 5.614 1.460 1.00 0.00 ATOM 108 CB PRO 130 12.759 4.431 3.049 1.00 0.00 ATOM 109 1HB PRO 130 12.555 5.413 3.449 1.00 0.00 ATOM 110 2HB PRO 130 13.397 3.892 3.732 1.00 0.00 ATOM 111 QB PRO 130 12.976 4.653 3.591 1.00 0.00 ATOM 112 CG PRO 130 11.490 3.678 2.783 1.00 0.00 ATOM 113 1HG PRO 130 10.655 4.365 2.771 1.00 0.00 ATOM 114 2HG PRO 130 11.344 2.928 3. 546 1.00 0.00

ATOM 115 QG PRO 130 10.999 3.647 3.159 1.00 0.00 ATOM 116 1HD PRO 130 10.695 2.992 0.922 1.00 0.00 ATOM 117 2HD PRO 130 12.056 2.031 1.540 1.00 0.00 ATOM 118 QD PRO 130 11.375 2.512 1.231 1. 00 0.00 ATOM 119 C PRO 130 14.847 3.908 1.741 1.00 0.00 ATOM 120 O PRO 130 15.703 4.161 0.897 1.00 0.00 ATOM 121 N ASP 131 15.046 3.062 2.741 1.00 0.00 ATOM 122 H ASP 131 14.325 2.914 3.378 1.00 0.00 ATOM 123 CA ASP 131 16.314 2.359 2.910 1.00 0.00 ATOM 124 HA ASP 131 17.090 3.017 2.546 1.00 0.00 ATOM 125 CB ASP 131 16.584 2.067 4.391 1.00 0.00 ATOM 126 1HB ASP 131 15.723 1.581 4.824 1.00 0.00 ATOM 127 2HB ASP 131 16.765 2.999 4.907 1.00 0.00 ATOM 128 QB ASP 131 16.244 2.290 4.866 1.00 0.00 ATOM 129 CG ASP 131 17.792 1.175 4.588 1.00 0.00 ATOM 130 OD1 ASP 131 17.645 0.118 5.225 1.00 0.00 ATOM 131 OD2 ASP 131 18.876 1.516 4.069 1.00 0.00 ATOM 132 C ASP 131 16.362 1. 065 2.085 1.00 0.00 ATOM 133 O ASP 131 16. 764 1.079 0.921 1.00 0.00 ATOM 134 N LYS+ 132 15.996-0.063 2.694 1.00 0.00 ATOM 135 H LYS+ 132 15.719-0.032 3.635 1.00 0.00 ATOM 136 CA LYS+ 132 16.046-1.349 1.997 1.00 0.00 ATOM 137 HA LYS+ 132 16.558-1.188 1. 061 1.00 0.00 ATOM 138 CB LYS+ 132 16. 830-2.385 2.813 1.00 0.00 ATOM 139 1HB LYS+ 132 16.639-3.366 2.401 1.00 0.00 ATOM 140 2HB LYS+ 132 16.480-2.362 3.835 1.00 0.00 ATOM 141 QB LYS+ 132 16.559-2.864 3.118 1.00 0.00 ATOM 142 CG LYS+ 132 18.336-2.156 2.820 1.00 0.00 ATOM 143 1HG LYS+ 132 18.813-3.003 3.293 1.00 0.00 ATOM 144 2HG LYS+ 132 18.551-1.260 3.385 1.00 0.00 ATOM 145 QG LYS+ 132 18.682-2.131 3.339 1.00 0.00 ATOM 146 CD LYS+ 132 18.891-1.999 1.410 1.00 0.00 ATOM 147 1HD LYS+ 132 18.076-1.779 0.733 1.00 0.00 ATOM 148 2HD LYS+ 132 19.365-2.925 1.116 1.00 0.00 ATOM 149 QD LYS+ 132 18.720-2.352 0.925 1.00 0.00 ATOM 150 CE LYS+ 132 19.917-0.876 1.338 1.00 0.00 ATOM 151 1HE LYS+ 132 20.293-0.815 0.327 1.00 0.00 ATOM 152 2HE LYS+ 132 20.731-1.107 2.010 1.00 0.00 ATOM 153 QE LYS+ 132 20.512-0.961 1.169 1.00 0.00 ATOM 154 NZ LYS+ 132 19.335 0.440 1.720 1.00 0.00 ATOM 155 1HZ LYS+ 132 19.220 0.503 2.765 1.00 0.00 ATOM 156 2HZ LYS+ 132 18.397 0.565 1.280 1.00 0.00 ATOM 157 3HZ LYS+ 132 19.950 1.215 1.411 1.00 0.00 ATOM 158 QZ LYS+ 132 19.189 0.761 1.819 1.00 0.00 ATOM 159 C LYS+ 132 14.653-1.882 1.695 1.00 0.00 ATOM 160 O LYS+ 132 14.499-2.877 0.990 1.00 0.00 ATOM 161 N CYS 133 13.638-1.219 2.214 1.00 0.00 ATOM 162 H CYS 133 13.812-0.428 2.760 1.00 0.00 ATOM 163 CA CYS 133 12.269-1.637 1.970 1.00 0.00 ATOM 164 HA CYS 133 12.284-2.688 1.724 1.00 0.00 ATOM 165 CB CYS 133 11.398-1.423 3.207 1.00 0.00 ATOM 166 1HB CYS 133 10.399-1.178 2.885 1.00 0.00 ATOM 167 2HB CYS 133 11.793-0.598 3.774 1.00 0.00 ATOM 168 QB CYS 133 11.096-0.888 3.330 1.00 0.00 ATOM 169 SG CYS 133 11.278-2.854 4.333 1.00 0.00 ATOM 170 C CYS 133 11.695-0.865 0.792 1.00 0.00 ATOM 171 O CYS 133 12.100 0.260 0.527 1.00 0.00 ATOM 172 N LYS+ 134 10.752-1.468 0.093 1.00 0.00 ATOM 173 H LYS+ 134 10.462-2.367 0.359 1.00 0.00 ATOM 174 CA LYS+ 134 10.123-0.836-1. 058 1.00 0.00 ATOM 175 HA LYS+ 134 10.811-0.104-1.455 1.00 0.00 ATOM 176 CB LYS+ 134 9.817-1.883-2. 134 1.00 0.00 ATOM 177 1HB LYS+ 134 8.837-2.299-1. 942 1.00 0.00 ATOM 178 2HB LYS+ 134 10.550-2.673-2. 067 1.00 0.00 ATOM 179 QB LYS+ 134 9.693-2.486-2. 004 1.00 0.00 ATOM 180 CG LYS+ 134 9.833-1.338-3. 555 1.00 0.00 ATOM 181 1HG LYS+ 134 10.682-0.679-3.668 1.00 0.00 ATOM 182 2HG LYS+ 134 8.921-0.787-3.727 1.00 0.00 ATOM 183 QG LYS+ 134 9. 801-0.733-3. 697 1.00 0.00 ATOM 184 CD LYS+ 134 9.935-2.461-4. 579 1.00 0.00 ATOM 185 1HD LYS+ 134 10.244-3.366-4. 074 1.00 0.00 ATOM 186 2HD LYS+ 134 10.672-2.195-5. 324 1.00 0.00

ATOM 187 QD LYS+ 134 10.458-2.780-4.699 1.00 0.00 ATOM 188 CE LYS+ 134 8.604-2.714-5.270 1.00 0.00 ATOM 189 1HE LYS+ 134 7.952-3.233-4.581 1.00 0.00 ATOM 190 2HE LYS+ 134 8.775-3.335-6.137 1.00 0. 00 ATOM 191 QE LYS+ 134 8.363-3.284-5.359 1.00 0.00 ATOM 192 NZ LYS+ 134 7.946-1.448-5.701 1.00 0.00 ATOM 193 1HZ LYS+ 134 8.613-0.653-5.627 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.119-1.249-5.097 1.00 0.00 ATOM 195 3HZ LYS+ 134 7.627-1.529-6.688 1.00 0.00 ATOM 196 QZ LYS+ 134 7.786-1.144-5.804 1.00 0.00 ATOM 197 C LYS+ 134 8.842-0.140-0.632 1.00 0.00 ATOM 198 O LYS+ 134 7.860-0.796-0.303 1.00 0.00 ATOM 199 N PHE 135 8.856 1.182-0.637 1.00 0.00 ATOM 200 H PHE 135 9.670 1.653-0.909 1.00 0.00 ATOM 201 CA PHE 135 7.686 1.951-0.241 1.00 0.00 ATOM 202 HA PHE 135 7.095 1.339 0.425 1.00 0.00 ATOM 203 CB PHE 135 8.120 3.222 0.498 1.00 0.00 ATOM 204 1HB PHE 135 8.657 3.860-0.189 1.00 0.00 ATOM 205 2HB PHE 135 8.778 2.947 1.307 1.00 0.00 ATOM 206 QB PHE 135 8.717 3.404 0.559 1.00 0.00 ATOM 207 QD PHE 135 6.873 4.119 1.156 1.00 0.00 ATOM 208 QE PHE 135 5.052 5.449 2.139 1.00 0.00 ATOM 209 QR PHE 135 5.597 5.050 1.844 1.00 0.00 ATOM 210 CG PHE 135 6.996 4.028 1.088 1.00 0.00 ATOM 211 CD1 PHE 135 7.056 5.412 1.097 1.00 0.00 ATOM 212 1HD PHE 135 7.914 5.908 0.665 1.00 0.00 ATOM 213 CE1 PHE 135 6.035 6.162 1.648 1.00 0.00 ATOM 214 1HE PHE 135 6.094 7.241 1.649 1.00 0.00 ATOM 215 CZ PHE 135 4.939 5.530 2.198 1.00 0.00 ATOM 216 HZ PHE 135 4.136 6.113 2.631 1.00 0.00 ATOM 217 CE2 PHE 135 4.868 4.152 2.196 1.00 0.00 ATOM 218 2HE PHE 135 4.010 3.656 2.628 1.00 0.00 ATOM 219 CD2 PHE 135 5.891 3.409 1.644 1.00 0.00 ATOM 220 2HD PHE 135 5.832 2.330 1.646 1.00 0.00 ATOM 221 C PHE 135 6.851 2.295-1.464 1.00 0.00 ATOM 222 O PHE 135 7.298 3.018-2.357 1.00 0.00 ATOM 223 N LEU 136 5.642 1.756-1.504 1.00 0.00 ATOM 224 H LEU 136 5.350 1.179-0.761 1.00 0.00 ATOM 225 CA LEU 136 4.736 1.984-2.612 1.00 0.00 ATOM 226 HA LEU 136 5.279 2.506-3.385 1.00 0.00 ATOM 227 CB LEU 136 4.215 0.654-3.171 1.00 0.00 ATOM 228 1HB LEU 136 3.426 0.873-3.877 1.00 0.00 ATOM 229 2HB LEU 136 3.791 0.087-2.354 1.00 0.00 ATOM 230 QB LEU 136 3.608 0.480-3.115 1.00 0.00 ATOM 231 CG LEU 136 5.257-0.221-3.876 1.00 0.00 ATOM 232 HG LEU 136 6.047 0.407-4.256 1.00 0.00 ATOM 233 QD1 LEU 136 6.009-1.450-2.667 1.00 0.00 ATOM 234 QD2 LEU 136 4.476-1.132-5.323 1.00 0.00 ATOM 235 CD1 LEU 136 5.866-1.214-2.901 1.00 0.00 ATOM 236 1HD1 LEU 136 6.562-0.703-2.251 1.00 0.00 ATOM 237 2HD1 LEU 136 6.383-1.988-3.447 1.00 0.00 ATOM 238 3HD1 LEU 136 5.082-1.659-2.305 1.00 0.00 ATOM 239 CD2 LEU 136 4.626-0.957-5.047 1.00 0.00 ATOM 240 1HD2 LEU 136 4.962-0.518-5.975 1.00 0.00 ATOM 241 2HD2 LEU 136 3.551-0.880-4.981 1.00 0.00 ATOM 242 3HD2 LEU 136 4.914-1.998-5.015 1.00 0.00 ATOM 243 QQD LEU 136 5.242-1.291-3.995 1.00 0.00 ATOM 244 C LEU 136 3.568 2.845-2.164 1.00 0.00 ATOM 245 O LEU 136 2.495 2.336-1.846 1.00 0.00 ATOM 246 N HIS+ 137 3.780 4.150-2.145 1.00 0.00 ATOM 247 H HIS+ 137 4.656 4.498-2.412 1.00 0.00 ATOM 248 CA HIS+ 137 2.738 5.080-1.749 1.00 0.00 ATOM 249 HA HIS+ 137 2.036 4.544-1.117 1.00 0.00 ATOM 250 CB HIS+ 137 3.334 6.264-0.966 1.00 0.00 ATOM 251 1HB HIS+ 137 4.159 6.677-1.529 1.00 0.00 ATOM 252 2HB HIS+ 137 3.701 5.907-0.014 1.00 0.00 ATOM 253 QB HIS+ 137 3.930 6.292-0.771 1.00 0.00 ATOM 254 CG HIS+ 137 2.358 7.375-0.694 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.980 8.293-1.649 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.664 7.695 0.423 1.00 0. 00 ATOM 257 1HD HIS+ 137 2.312 8.327-2.573 1.00 0.00 ATOM 258 CE1 HIS+ 137 1.095 9.127-1.133 1.00 0. 00

ATOM 259 NE2 HIS+ 137 0.881 8.786 0.125 1.00 0.00 ATOM 260 2HD HIS+ 137 1.719 7.188 1.380 1.00 0.00 ATOM 261 1HE HIS+ 137 0.617 9.944-1.654 1.00 0.00 ATOM 262 2HE HIS+ 137 0.095 9.066 0.647 1.00 0.00 ATOM 263 C HIS+ 137 2.019 5.577-2.996 1.00 0.00 ATOM 264 O HIS+ 137 2.570 6.374-3.761 1.00 0.00 ATOM 265 N GLN 138 0.801 5. 105-3.212 1.00 0.00 ATOM 266 H GLN 138 0.409 4.465-2.574 1.00 0.00 ATOM 267 CA GLN 138 0.034 5.513-4.380 1.00 0.00 ATOM 268 HA GLN 138 0.429 6.459-4.717 1.00 0.00 ATOM 269 CB GLN 138 0.177 4.486-5.507 1.00 0.00 ATOM 270 1HB GLN 138-0.642 4.612-6.198 1.00 0.00 ATOM 271 2HB GLN 138 0.128 3.495-5.082 1.00 0.00 ATOM 272 QB GLN 138-0.257 4.054-5.640 1.00 0.00 ATOM 273 CG GLN 138 1.480 4.608-6.284 1.00 0.00 ATOM 274 1HG GLN 138 2.012 5.481-5.935 1.00 0.00 ATOM 275 2HG GLN 138 1.249 4.723-7.333 1.00 0.00 ATOM 276 QG GLN 138 1. 630 5.102-6.634 1.00 0.00 ATOM 277 CD GLN 138 2.373 3.396-6.118 1.00 0.00 ATOM 278 OE1 GLN 138 2.000 2.284-6.483 1.00 0.00 ATOM 279 NE2 GLN 138 3.561 3.601-5.565 1.00 0.00 ATOM 280 1HE2 GLN 138 3.797 4.514-5.295 1.00 0.00 ATOM 281 2HE2 GLN 138 4.152 2.831-5.448 1.00 0.00 ATOM 282 QE2 GLN 138 3.974 3.673-5.371 1.00 0.00 ATOM 283 C GLN 138-1.435 5.694-4.031 1.00 0.00 ATOM 284 O GLN 138-2.027 4.872-3.329 1.00 0.00 ATOM 285 N GLU 139-2.015 6.772-4.531 1.00 0.00 ATOM 286 H GLU 139-1.489 7.382-5.084 1.00 0.00 ATOM 287 CA GLU 139-3.415 7.072-4.284 1.00 0.00 ATOM 288 HA GLU 139-3.704 6.575-3.370 1.00 0.00 ATOM 289 CB GLU 139-3.608 8.579-4.114 1.00 0.00 ATOM 290 1HB GLU 139-4.576 8.758-3.669 1.00 0.00 ATOM 291 2HB GLU 139-3.574 9.049-5.085 1.00 0.00 ATOM 292 QB GLU 139-4.075 8.904-4.377 1.00 0.00 ATOM 293 CG GLU 139-2.554 9.226-3.228 1.00 0.00 ATOM 294 1HG GLU 139-2.452 10.264-3.507 1.00 0.00 ATOM 295 2HG GLU 139-1.613 8.718-3.380 1.00 0.00 ATOM 296 QG GLU 139-2.033 9.491-3.443 1.00 0.00 ATOM 297 CD GLU 139-2.907 9.152-1.758 1.00 0.00 ATOM 298 OE1 GLU 139-3.883 8.451-1.415 1.00 0.00 ATOM 299 OE2 GLU 139-2.206 9.791-0.948 1.00 0.00 ATOM 300 C GLU 139-4.279 6.548-5.425 1.00 0.00 ATOM 301 O GLU 139-4.231 7.059-6.545 1.00 0.00 ATOM 302 N ARG+ 140-5.062 5.522-5.136 1.00 0.00 ATOM 303 H ARG+ 140-5.056 5.156-4.225 1.00 0.00 ATOM 304 CA ARG+ 140-5.935 4.921-6.130 1.00 0.00 ATOM 305 HA ARG+ 140-5.521 5.129-7.105 1.00 0.00 ATOM 306 CB ARG+ 140-5.996 3.397-5.922 1.00 0.00 ATOM 307 1HB ARG+ 140-6.421 3.204-4.945 1.00 0.00 ATOM 308 2HB ARG+ 140-4.994 3.001-5.950 1.00 0.00 ATOM 309 QB ARG+ 140-5.708 3.103-5.447 1.00 0.00 ATOM 310 CG ARG+ 140-6.832 2.653-6.949 1.00 0.00 ATOM 311 1HG ARG+ 140-7.852 3.003-6.886 1.00 0.00 ATOM 312 2HG ARG+ 140-6.800 1.597-6.727 1.00 0.00 ATOM 313 QG ARG+ 140-7.326 2.300-6.806 1.00 0.00 ATOM 314 CD ARG+ 140-6.320 2.876-8.358 1.00 0.00 ATOM 315 1HD ARG+ 140-5.904 3.872-8.422 1.00 0.00 ATOM 316 2HD ARG+ 140-7.152 2.795-9.047 1.00 0.00 ATOM 317 QD ARG+ 140-6.528 3.334-8.734 1.00 0.00 ATOM 318 NE ARG+ 140-5.296 1.909-8.736 1.00 0.00 ATOM 319 HE ARG+ 140-4.932 1.335-8.027 1.00 0.00 ATOM 320 CZ ARG+ 140-4.824 1.794-9.975 1.00 0.00 ATOM 321 NH1 ARG+ 140-5.368 2.510-10.957 1.00 0.00 ATOM 322 1HH1 ARG+ 140-6.141 3.137-10.760 1.00 0.00 ATOM 323 2HH1 ARG+ 140-5.022 2.435-11.891 1.00 0.00 ATOM 324 QH1 ARG+ 140-5.582 2.786-11.325 1.00 0.00 ATOM 325 NH2 ARG+ 140-3.834 0.945-10.236 1.00 0.00 ATOM 326 1HH2 ARG+ 140-3. 441 0.391-9.501 1.00 0.00 ATOM 327 2HH2 ARG+ 140-3.477 0.860-11.167 1.00 0.00 ATOM 328 QH2 ARG+ 140-3.459 0.626-10.334 1.00 0.00 ATOM 329 C ARG+ 140-7.331 5.526-6.043 1.00 0.00 ATOM 330 O ARG+ 140-8.224 4.962-5.413 1.00 0.00

ATOM 331 N MET 141-7. 520 6.671-6.693 1.00 0.00 ATOM 332 H MET 141-6.771 7.064-7.188 1.00 0.00 ATOM 333 CA MET 141-8. 816 7.354-6.703 1.00 0. 00 ATOM 334 HA MET 141-9.199 7.357-5.695 1.00 0. 00 ATOM 335 CB MET 141-8.633 8.803-7.181 1.00 0.00 ATOM 336 1HB MET 141-8.436 8.790-8.245 1.00 0.00 ATOM 337 2HB MET 141-7.781 9.230-6.675 1.00 0.00 ATOM 338 QB MET 141-8.109 9.010-7.460 1.00 0.00 ATOM 339 CG MET 141-9.835 9.706-6.934 1.00 0.00 ATOM 340 1HG MET 141-10.727 9.184-7.251 1.00 0.00 ATOM 341 2HG MET 141-9.718 10.603-7.524 1.00 0.00 ATOM 342 QG MET 141-10. 223 9.894-7.387 1.00 0.00 ATOM 343 SD MET 141-10.022 10.175-5.204 1.00 0.00 ATOM 344 QE MET 141-9.970 12.321-5.359 1.00 0.00 ATOM 345 CE MET 141-9.979 11.962-5.333 1.00 0.00 ATOM 346 1HE MET 141-8.954 12.300-5.303 1.00 0.00 ATOM 347 2HE MET 141-10.526 12.396-4.509 1.00 0.00 ATOM 348 3HE MET 141-10.430 12.268-6.266 1.00 0.00 ATOM 349 C MET 141-9.808 6.614-7.612 1.00 0.00 ATOM 350 O MET 141-10.700 7.219-8.211 1.00 0.00 ATOM 351 N ASP 142-9.647 5.301-7.697 1.00 0.00 ATOM 352 H ASP 142-8.926 4.878-7.186 1.00 0.00 ATOM 353 CA ASP 142-10.503 4.468-8.515 1.00 0.00 ATOM 354 HA ASP 142-11.156 5.109-9.086 1.00 0.00 ATOM 355 CB ASP 142-9.657 3.625-9.474 1.00 0.00 ATOM 356 1HB ASP 142-10.315 3.072-10.116 1.00 0.00 ATOM 357 2HB ASP 142-9.062 2.932-8.901 1.00 0.00 ATOM 358 QB ASP 142-9.689 3.002-9.508 1.00 0.00 ATOM 359 CG ASP 142-8.721 4.446-10.342 1.00 0.00 ATOM 360 OD1 ASP 142-9.033 5.617-10.617 1.00 0.00 ATOM 361 OD2 ASP 142-7.666 3.907-10.744 1.00 0.00 ATOM 362 C ASP 142-11.333 3.537-7.646 1.00 0.00 ATOM 363 O ASP 142-12.562 3.512-7.729 1.00 0.00 ATOM 364 N VAL 143-10.648 2.756-6.823 1.00 0.00 ATOM 365 H VAL 143-9.671 2.816-6.813 1.00 0.00 ATOM 366 CA VAL 143-11.307 1.793-5.952 1.00 0.00 ATOM 367 HA VAL 143-12. 255 1.539-6.402 1.00 0.00 ATOM. 368 CB VAL 143-10.466 0.502-5.840 1.00 0.00 ATOM 369 HB VAL 143-9.830 0.587-4.969 1.00 0.00 ATOM 370 QG1 VAL 143-11.565-1.002-5.616 1.00 0.00 ATOM 371 QG2 VAL 143-9.367 0.277-7.349 1.00 0.00 ATOM 372 CG1 VAL 143-11.357-0.713-5.658 1.00 0.00 ATOM 373 1HG1 VAL 143-10.827-1.593-5.993 1.00 0.00 ATOM 374 2HG1 VAL 143-12.257-0.591-6.241 1.00 0.00 ATOM 375 3HG1 VAL 143.-11. 612-0.821-4.615 1.00 0.00 ATOM 376 CG2 VAL 143-9.577 0.321-7.061 1.00 0.00 ATOM 377 1HG2 VAL 143-8.547 0.488-6.784 1.00 0.00 ATOM 378 2HG2 VAL 143-9.865 1.028-7.825 1.00 0. 00 ATOM 379 3HG2 VAL 143-9.689-0.684-7.440 1.00 0.00 ATOM 380 QQG VAL 143-10.466-0.362-6.483 1.00 0.00 ATOM 381 C VAL 143-11.565 2.375-4.558 1.00 0.00 ATOM 382 O VAL 143-10.959 3.371-4.167 1.00 0.00 ATOM 383 N CYS 144-12.483 1.748-3.825 1.00 0.00 ATOM 384 H CYS 144-12.933 0.963-4.204 1.00 0.00 ATOM 385 CA CYS 144-12.850 2.183-2.475 1.00 0.00 ATOM 386 HA CYS 144-12.005 2.702-2.034 1.00 0.00 ATOM 387 CB CYS 144-14. 058 3.119-2.530 1.00 0.00 ATOM 388 1HB CYS 144-14.624 3.011-1.615 1.00 0.00 ATOM 389 2HB CYS 144-14.682 2.837-3.364 1.00 0.00 ATOM 390 QB CYS 144-14.653 2.924-2.489 1.00 0.00 ATOM 391 SG CYS 144-13.643 4.879-2.721 1.00 0.00 ATOM 392 C CYS 144-13.198 0.980-1.617 1.00 0.00 ATOM 393 O CYS 144-14.360 0.587-1.542 1.00 0.00 ATOM 394 N GLU 145-12.200 0.384-0.988 1.00 0.00 ATOM 395 H GLU 145-11.287 0.723-1.091 1.00 0.00 ATOM 396 CA GLU 145-12.427-0.788-0.170 1.00 0. 00 ATOM 397 HA GLU 145-13.471-1.050-0.249 1.00 0.00 ATOM 398 CB GLU 145-11.596-1.937-0. 713 1.00 0.00 ATOM 399 1HB GLU 145-11.349-2.607 0.094 1.00 0.00 ATOM 400 2HB GLU 145-10.681-1.541-1.135 1.00 0.00 ATOM 401 QB GLU 145-11.015-2.074-0. 520 1.00 0.00 ATOM 402 CG GLU 145-12.332-2.724-1. 779 1.00 0.00

ATOM 403 1HG GLU 145-11.747-3.593-2.042 1.00 0.00 ATOM 404 2HG GLU 145-12.465-2.098-2.649 1.00 0.00 ATOM 405 QG GLU 145-12.106-2.845-2.345 1.00 0.00 ATOM 406 CD GLU 145-13.689-3.180-1.292 1.00 0.00 ATOM 407 OE1 GLU 145-14.674-3.008-2.031 1.00 0.00 ATOM 408 OE2 GLU 145-13.762-3.699-0.156 1.00 0.00 ATOM 409 C GLU 145-12.091-0.543 1.289 1.00 0.00 ATOM 410 O GLU 145-11.687 0.555 1.673 1.00 0.00 ATOM 411 N THR 146-12.267-1.580 2.094 1.00 0.00 ATOM 412 H THR 146-12.595-2.425 1.715 1.00 0.00 ATOM 413 CA THR 146-11.994-1.508 3.517 1.00 0.00 ATOM 414 HA THR 146-12.320-0.539 3.868 1.00 0.00 ATOM 415 CB THR 146-12. 790-2.595 4.245 1.00 0.00 ATOM 416 HB THR 146-12.223-3.517 4.227 1.00 0.00 ATOM 417 QG2 THR 146-13.174-2.186 6.035 1.00 0.00 ATOM 418 OG1 THR 146-14.026-2.818 3.586 1.00 0.00 ATOM 419 1HG THR 146-14.676-3.147 4.218 1.00 0.00 ATOM 420 CG2 THR 146-13.099-2.265 5.690 1.00 0.00 ATOM 421 1HG2 THR 146-13.605-3.101 6.152 1.00 0.00 ATOM 422 2HG2 THR 146-13.737-1.392 5.734 1.00 0.00 ATOM 423 3HG2 THR 146-12.180-2.065 6.219 1.00 0.00 ATOM 424 C THR 146-10.498-1.651 3.790 1.00 0.00 ATOM 425 O THR 146-9.726-2.026 2.905 1.00 0.00 ATOM 426 N HIS+ 147-10.107-1.346 5.024 1.00 0.00 ATOM 427 H HIS+ 147-10.784-1.052 5.668 1.00 0.00 ATOM 428 CA HIS+ 147-8.713-1.424 5.460 1.00 0.00 ATOM 429 HA HIS+ 147-8.156-0.651 4.952 1.00 0.00 ATOM 430 CB HIS+ 147-8. 641-1. 181 6.972 1.00 0.00 ATOM 431 1HB HIS+ 147-8. 460-2.123 7.471 1.00 0.00 ATOM 432 2HB HIS+ 147-9.584-0.779 7.310 1.00 0.00 ATOM 433 QB HIS+ 147-9.022-1.451 7.391 1.00 0.00 ATOM 434 CG HIS+ 147-7.565-0.228 7.385 1.00 0.00 ATOM 435 ND1 HIS+ 147-7.725 0.708 8.385 1.00 0.00 ATOM 436 CD2 HIS+ 147-6.306-0.071 6.926 1.00 0.00 ATOM 437 1HD HIS+ 147-8.538 0.849 8.918 1.00 0.00 ATOM 438 CE1 HIS+ 147-6.605 1.399 8.518 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.728 0.945 7.643 1.00 0.00 ATOM 440 2HD HIS+ 147-5.839-0.640 6.133 1.00 0.00 ATOM 441 1HE HIS+ 147-6.435 2.197 9.222 1.00 0.00 ATOM 442 2HE HIS+ 147-4.880 1.387 7.416 1.00 0.00 ATOM 443 C HIS+ 147-8.090-2.783 5. 139 1.00 0.00 ATOM 444 O HIS+ 147-6.911-2.873 4.796 1.00 0.00 ATOM 445 N LEU 148-8.889-3.835 5.269 1.00 0.00 ATOM 446 H LEU 148-9.813-3.697 5.554 1.00 0.00 ATOM 447 CA LEU 148-8.424-5.190 5.016 1.00 0.00 ATOM 448 HA LEU 148-7.510-5.332 5.572 1.00 0.00 ATOM 449 CB LEU 148-9.463-6.197 5.521 1.00 0.00 ATOM 450 1HB LEU 148-10.426-5.921 5.119 1.00 0.00 ATOM 451 2HB LEU 148-9.506-6.127 6.598 1.00 0.00 ATOM 452 QB LEU 148-9.966-6.024 5.859 1.00 0.00 ATOM 453 CG LEU 148-9.189-7.652 5.146 1.00 0.00 ATOM 454 HG LEU 148-8.768-7.685 4.153 1.00 0.00 ATOM 455 QD1 LEU 148-7.947-8.419 6.331 1.00 0.00 ATOM 456 QD2 LEU 148-10.787-8.642 5.137 1.00 0.00 ATOM 457 CD1 LEU 148-8. 185-8.271 6. 104 1.00 0.00 ATOM 458 1HD1 LEU 148-8.107-9.331 5.907 1.00 0.00 ATOM 459 2HD1 LEU 148-8.514-8.118 7.121 1.00 0.00 ATOM 460 3HD1 LEU 148-7.220-7.808 5.963 1.00 0.00 ATOM 461 CD2 LEU 148-10.481-8.452 5.138 1.00 0.00 ATOM 462 1HD2 LEU 148-10.952-8.387 6.108 1.00 0.00 ATOM 463 2HD2 LEU 148-10. 262-9.485 4.914 1.00 0. 00 ATOM 464 3HD2 LEU 148-11.147-8.054 4.387 1.00 0.00 ATOM 465 QQD LEU 148-9.367-8. 530 5.734 1.00 0.00 ATOM 466 C LEU 148-8.134-5.434 3.536 1.00 0.00 ATOM 467 O LEU 148-7. 146-6. 085 3.200 1.00 0.00 ATOM 468 N HIS+ 149-8.993-4.928 2.652 1.00 0.00 ATOM 469 H HIS+ 149-9.769-4.423 2.967 1.00 0.00 ATOM 470 CA HIS+ 149-8.796-5. 130 1.219 1.00 0.00 ATOM 471 HA HIS+ 149-8.745-6.197 1.056 1.00 0.00 ATOM 472 CB HIS+ 149-9. 957-4. 575 0.398 1.00 0.00 ATOM 473 1HB HIS+ 149-9.590-3.785-0.243 1.00 0.00 ATOM 474 2HB HIS+ 149-10.713-4.172 1.056 1.00 0. 00

ATOM 475 QB HIS+ 149-10.152-3.978 0.407 1.00 0.00 ATOM 476 CG HIS+ 149-10.592-5.616-0.473 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.950-5.699-0.691 1.00 0.00 ATOM 478 CD2 HIS+ 149-10.038-6.628-1.184 1.00 0.00 ATOM 479 1HD HIS+ 149-12.636-5.077-0.332 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.204-6.717-1.495 1.00 0.00 ATOM 481 NE2 HIS+ 149-11.061-7.296-1.810 1.00 0.00 ATOM 482 2HD HIS+ 149-8.984-6.864-1.249 1.00 0.00 ATOM 483 1HE HIS+ 149-13.183-7.018-1.841 1.00 0.00 ATOM 484 2HE HIS+ 149-10.949-7.974-2.510 1.00 0.00 ATOM 485 C HIS+ 149-7.487-4.524 0.747 1.00 0.00 ATOM 486 O HIS+ 149-6.695-5.202 0.102 1.00 0.00 ATOM 487 N TRP 150-7.252-3.258 1.073 1.00 0.00 ATOM 488 H TRP 150-7.921-2.761 1.593 1.00 0.00 ATOM 489 CA TRP 150-6.011-2.593 0.672 1.00 0.00 ATOM 490 HA TRP 150-5.931-2.654-0.404 1.00 0.00 ATOM 491 CB TRP 150-6.002-1.128 1.106 1.00 0.00 ATOM 492 1HB TRP 150-5.022-0.715 0.915 1.00 0.00 ATOM 493 2HB TRP 150-6.205-1.075 2.165 1.00 0.00 ATOM 494 QB TRP 150-5.614-0.895 1.540 1.00 0.00 ATOM 495 CG TRP 150-7.009-0.268 0.405 1.00 0.00 ATOM 496 CD1 TRP 150-7. 468 0.946 0.823 1.00 0.00 ATOM 497 CD2 TRP 150-7. 677-0.543-0.834 1.00 0.00 ATOM 498 CE3 TRP 150-7. 644-1.603-1.745 1.00 0.00 ATOM 499 CE2 TRP 150-8.527 0.546-1.097 1.00 0.00 ATOM 500 NE1 TRP 150-8. 383 1.438-0.073 1.00 0.00 ATOM 501 HD TRP 150-7.152 1.435 1.732 1.00 0.00 ATOM 502 3HE TRP 150-7. 007-2.459-1.582 1.00 0.00 ATOM 503 CZ3 TRP 150-8.442-1.543-2.864 1.00 0.00 ATOM 504 CZ2 TRP 150-9.329 0.604-2.230 1.00 0.00 ATOM 505 1HE TRP 150-8. 857 2.295 0.008 1.00 0.00 ATOM 506 3HZ TRP 150-8. 432-2.355-3.575 1.00 0.00 ATOM 507 CH2 TRP 150-9.273-0.448-3.097 1.00 0.00 ATOM 508 2HZ TRP 150-9. 979 1.444-2.431 1.00 0.00 ATOM 509 HH TRP 150-9.882-0.446-3.988 1.00 0.00 ATOM 510 C TRP 150-4.817-3.301 1.267 1.00 0.00 ATOM 511 O TRP 150-3.772-3.384 0.638 1.00 0.00 ATOM 512 N HIS+ 151-4. 981-3.831 2.470 1.00 0.00 ATOM 513 H HIS+ 151-5.849-3.747 2.921 1.00 0.00 ATOM 514 CA HIS+ 151-3.906-4.560 3.117 1.00 0.00 ATOM 515 HA HIS+ 151-3.042-3.913 3.164 1.00 0.00 ATOM 516 CB HIS+ 151-4.318-4.980 4.537 1.00 0.00 ATOM 517 1HB HIS+ 151-5.169-5.644 4.470 1.00 0.00 ATOM 518 2HB HIS+ 151-4.603-4.101 5.095 1.00 0.00 ATOM 519 QB HIS+ 151-4.886-4.872 4.783 1.00 0.00 ATOM 520 CG HIS+ 151-3.245-5.689 5. 314 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.890-5.343 6.600 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.463-6.744 4.983 1.00 0.00 ATOM 523 1HD HIS+ 151-3.277-4.609 7.126 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.937-6.155 7.025 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.661-7.015 6.064 1.00 0.00 ATOM 526 2HD HIS+ 151-2.464-7.264 4.032 1.00 0.00 ATOM 527 1HE HIS+ 151-1.458-6.116 7.993 1.00 0.00 ATOM 528 2HE HIS+ 151-1.096-7.809 6.166 1.00 0.00 ATOM 529 C HIS+ 151-3.564-5.781 2.278 1.00 0.00 ATOM 530 O HIS+ 151-2.395-6.063 2.026 1.00 0.00 ATOM 531 N THR 152-4.595-6.491 1.845 1.00 0.00 ATOM 532 H THR 152-5.504-6.206 2.077 1.00 0.00 ATOM 533 CA THR 152-4.412-7.674 1.028 1.00 0.00 ATOM 534 HA THR 152-3.708-8.316 1.535 1.00 0.00 ATOM 535 CB THR 152-5.738-8.422 0.866 1.00 0.00 ATOM 536 HB THR 152-6.352-7.897 0.148 1.00 0.00 ATOM 537 QG2 THR 152-5.532-10.185 0.266 1.00 0.00 ATOM 538 OG1 THR 152-6. 434-8.476 2.102 1.00 0.00 ATOM 539 1HG THR 152-6.673-7.584 2.380 1.00 0.00 ATOM 540 CG2 THR 152-5.571-9.846 0.382 1.00 0.00 ATOM 541 1HG2 THR 152-6.541-10.313 0.300 1.00 0.00 ATOM 542 2HG2 THR 152-4.964-10.397 1.085 1.00 0.00 ATOM 543 3HG2 THR 152-5.090-9.844-0.587 1.00 0.00 ATOM 544 C THR 152-3.831-7.311-0.330 1.00 0.00 ATOM 545 O THR 152-2.844-7.903-0.738 1.00 0.00 ATOM 546 N VAL 153-4.429-6.326-1.009 1.00 0.00

ATOM 547 H VAL 153-5.208-5.872-0.613 1.00 0.00 ATOM 548 CA VAL 153-3. 940-5.895-2.320 1.00 0.00 ATOM 549 HA VAL 153-4.004-6.739-2.989 1.00 0.00 ATOM 550 CB VAL 153-4.792-4.743-2.902 1.00 0.00 ATOM 551 HB VAL 153-4.717-3.893-2.240 1.00 0.00 ATOM 552 QG1 VAL 153-4.158-4.232-4.598 1.00 0.00 ATOM 553 QG2 VAL 153-6.598-5.255-3.007 1.00 0.00 ATOM 554 CG1 VAL 153-4.279-4.329-4.274 1.00 0.00 ATOM 555 1HG1 VAL 153-3.207-4.460-4.313 1.00 0.00 ATOM 556 2HG1 VAL 153-4.523-3.292-4.452 1.00 0.00 ATOM 557 3HG1 VAL 153-4.744-4.944-5.031 1.00 0.00 ATOM 558 CG2 VAL 153-6.253-5.156-2.987 1.00 0.00 ATOM 559 1HG2 VAL 153-6.790-4.455-3.608 1.00 0.00 ATOM 560 2HG2 VAL 153-6.684-5.164-1.996 1.00 0.00 ATOM 561 3HG2 VAL 153-6.321-6.145-3.418 1.00 0.00 ATOM 562 QQG VAL 153-5.378-4.743-3.803 1.00 0.00 ATOM 563 C VAL 153-2.487-5.463-2.231 1.00 0. 00 ATOM 564 O VAL 153-1.647-5.889-3.022 1.00 0.00 ATOM 565 N ALA 154-2.196-4.630-1.251 1.00 0.00 ATOM 566 H ALA 154-2.916-4.336-0.645 1.00 0.00 ATOM 567 CA ALA 154-0.844-4.150-1.036 1.00 0.00 ATOM 568 HA ALA 154-0.522-3.627-1.924 1.00 0.00 ATOM 569 QB ALA 154-0.820-2.950 0.405 1.00 0.00 ATOM 570 CB ALA 154-0.825-3.180 0.128 1.00 0.00 ATOM 571 1HB ALA 154-0.235-2.315-0.136 1.00 0.00 ATOM 572 2HB ALA 154-0.390-3.663 0.991 1.00 0.00 ATOM 573 3HB ALA 154-1.835-2.872 0.359 1.00 0.00 ATOM 574 C ALA 154 0.108-5.307-0.761 1.00 0.00 ATOM 575 O ALA 154 1.162-5.431-1.388 1.00 0.00 ATOM 576 N LYS+ 155-0.268-6.146 0.196 1.00 0.00 ATOM 577 H LYS+ 155-1.118-5.984 0.662 1.00 0.00 ATOM 578 CA LYS+ 155 0.544-7.289 0.583 1.00 0.00 ATOM 579 HA LYS+ 155 1.527-6.918 0.856 1.00 0.00 ATOM 580 CB LYS+ 155-0.074-7.997 1.794 1.00 0.00 ATOM 581 1HB LYS+ 155-0.963-8.520 1.472 1.00 0.00 ATOM 582 2HB LYS+ 155-0.354-7.252 2.526 1.00 0.00 ATOM 583 QB LYS+ 155-0.659-7.886 1.999 1.00 0.00 ATOM 584 CG LYS+ 155 0.855-9.000 2.465 1.00 0.00 ATOM 585 1HG LYS+ 155 1.390-8.502 3.261 1.00 0.00 ATOM 586 2HG LYS+ 155 1.558-9.372 1.734 1.00 0.00 ATOM 587 QG LYS+ 155 1.474-8.937 2.498 1.00 0.00 ATOM 588 CD LYS+ 155 0.081-10.174 3.048 1.00 0.00 ATOM 589 1HD LYS+ 155-0.977-9.960 2.990 1.00 0.00 ATOM 590 2HD LYS+ 155 0.366-10.301 4.084 1.00 0.00 ATOM 591 QD LYS+ 155-0.306-10.130 3.537 1.00 0.00 ATOM 592 CE LYS+ 155 0.366-11.468 2.297 1.00 0.00 ATOM 593 1HE LYS+ 155-0.442-12.161 2.482 1.00 0.00 ATOM 594 2HE LYS+ 155 1.291-11.889 2. 668 1.00 0.00 ATOM 595 QE LYS+ 155 0.424-12.025 2.575 1.00 0.00 ATOM 596 NZ LYS+ 155 0.491-11.247 0.829 1.00 0.00 ATOM 597 1HZ LYS+ 155-0.039-10.397 0.546 1.00 0.00 ATOM 598 2HZ LYS+ 155 0. 113-12. 064 0.308 1.00 0.00 ATOM 599 3HZ LYS+ 155 1.499-11.117 0.568 1.00 0.00 ATOM 600 QZ LYS+ 155 0.524-11.193 0.474 1.00 0.00 ATOM 601 C LYS+ 155 0.708-8.278-0.560 1.00 0.00 ATOM 602 O LYS+ 155 1.812-8.748-0.796 1.00 0.00 ATOM 603 N GLU 156-0.377-8.612-1.256 1.00 0.00 ATOM 604 H GLU 156-1.252-8.217-1.021 1.00 0.00 ATOM 605 CA GLU 156-0.292-9.569-2.355 1.00 0.00 ATOM 606 HA GLU 156 0.193-10.450-1.961 1.00 0.00 ATOM 607 CB GLU 156-1.677-9.981-2.878 1.00 0.00 ATOM 608 1HB GLU 156-2.280-10.312-2.044 1.00 0.00 ATOM 609 2HB GLU 156-1.555-10.806-3.563 1.00 0.00 ATOM 610 QB GLU 156-1. 918-10. 559-2. 803 1.00 0.00 ATOM 611 CG GLU 156-2.444-8. 891-3. 603 1.00 0.00 ATOM 612 1HG GLU 156-2.126-8.866-4.635 1.00 0.00 ATOM 613 2HG GLU 156-2.230-7.942-3.136 1.00 0.00 ATOM 614 QG GLU 156-2.178-8.404-3.885 1.00 0.00 ATOM 615 CD GLU 156-3.938-9.126-3.562 1.00 0.00 ATOM 616 OE1 GLU 156-4.682-8.333-4.169 1.00 0.00 ATOM 617 OE2 GLU 156-4.363-10. 104-2.913 1.00 0.00 ATOM 618 C GLU 156 0.582-9.032-3.477 1.00 0.00

ATOM 619 O GLU 156 1.346-9.783-4.060 1.00 0.00 ATOM 620 N THR 157 0.495-7.733-3.754 1.00 0.00 ATOM 621 H THR 157-0.128-7.172-3.240 1.00 0.00 ATOM 622 CA THR 157 1.319-7.122-4.795 1.00 0.00 ATOM 623 HA THR 157 1.111-7.633-5.724 1.00 0.00 ATOM 624 CB THR 157 0.967-5.636-4.951 1.00 0.00 ATOM 625 HB THR 157 1.112-5.141-4.001 1.00 0.00 ATOM 626 QG2 THR 157 2.011-4.747-6.230 1.00 0.00 ATOM 627 OG1 THR 157-0.388-5.476-5.333 1.00 0.00 ATOM 628 1HG THR 157-0.966-5.811-4.632 1.00 0.00 ATOM 629 CG2 THR 157 1.811-4.917-5.985 1.00 0.00 ATOM 630 1HG2 THR 157 2.555-5.595-6.377 1.00 0.00 ATOM 631 2HG2 THR 157 2.300-4.072-5.525 1.00 0.00 ATOM 632 3HG2 THR 157 1.178-4.573-6.790 1.00 0.00 ATOM 633 C THR 157 2.807-7.289-4.463 1.00 0.00 ATOM 634 O THR 157 3.621-7.603-5.330 1.00 0.00 ATOM 635 N CYS 158 3.156-7.085-3.197 1.00 0.00 ATOM 636 H CYS 158 2.467-6.838-2.544 1.00 0.00 ATOM 637 CA CYS 158 4.541-7.224-2.759 1.00 0.00 ATOM 638 HA CYS 158 5.168-6.770-3.512 1.00 0.00 ATOM 639 CB CYS 158 4.750-6.484-1.438 1.00 0.00 ATOM 640 1HB CYS 158 5.644-6.841-0.964 1.00 0.00 ATOM 641 2HB CYS 158 3.909-6.681-0.793 1.00 0.00 ATOM 642 QB CYS 158 4.776-6.761-0.878 1.00 0.00 ATOM 643 SG CYS 158 4.892-4.668-1.632 1.00 0.00 ATOM 644 C CYS 158 4.935-8.700-2.636 1.00 0.00 ATOM 645 0 CYS 158 6.010-9.095-3.089 1.00 0.00 ATOM 646 N SER 159 4.062-9.512-2.031 1.00 0.00 ATOM 647 H SER 159 3.222-9.139-1.689 1.00 0.00 ATOM 648 CA SER 159 4.321-10.945-1.861 1.00 0.00 ATOM 649 HA SER 159 5.292-11.050-1.399 1.00 0.00 ATOM 650 CB SER 159 3.272-11.587-0.956 1.00 0.00 ATOM 651 1HB SER 159 3.525-12.630-0.811 1.00 0.00 ATOM 652 2HB SER 159 2.303-11. 516-1.429 1.00 0.00 ATOM 653 QB SER 159 2.914-12.073-1.120 1.00 0.00 ATOM 654 OG SER 159 3.216-10.946 0.312 1.00 0.00 ATOM 655 HG SER 159 4.114-10.767 0.615 1.00 0.00 ATOM 656 C SER 159 4.342-11.682-3.201 1.00 0.00 ATOM 657 O SER 159 4.959-12.736-3.312 1.00 0.00 ATOM 658 N GLU 160 3.671-11.121-4.208 1.00 0.00 ATOM 659 H GLU 160 3.198-10.275-4.055 1.00 0.00 ATOM 660 CA GLU 160 3.631-11.722-5.541 1.00 0.00 ATOM 661 HA GLU 160 3.248-12.729-5.456 1.00 0.00 ATOM 662 CB GLU 160 2.726-10.900-6.472 1.00 0.00 ATOM 663 1HB GLU 160 3.165-9.920-6.601 1.00 0.00 ATOM 664 2HB GLU 160 1.759-10.790-6.007 1.00 0.00 ATOM 665 QB GLU 160 2.462-10.355-6.304 1.00 0.00 ATOM 666 CG GLU 160 2.522-11.509-7.852 1.00 0.00 ATOM 667 1HG GLU 160 1.491-11.376-8.141 1.00 0.00 ATOM 668 2HG GLU 160 2.750-12.563-7.805 1.00 0.00 ATOM 669 QG GLU 160 2.120-11.969-7.973 1.00 0.00 ATOM 670 CD GLU 160 3.407-10.871-8.904 1.00 0.00 ATOM 671 OE1 GLU 160 4.003-9.808-8.620 1.00 0.00 ATOM 672 OE2 GLU 160 3.544-11.450-10.000 1.00 0.00 ATOM 673 C GLU 160 5.041-11.762-6.100 1.00 0.00 ATOM 674 O GLU 160 5.414-12.652-6.870 1.00 0.00 ATOM 675 N LYS+ 161 5.826-10.784-5.688 1.00 0.00 ATOM 676 H LYS+ 161 5.471-10.115-5.069 1.00 0.00 ATOM 677 CA LYS+ 161 7.194-10.687-6.114 1.00 0.00 ATOM 678 HA LYS+ 161 7.316-11.307-6.989 1.00 0. 00 ATOM 679 CB LYS+ 161 7. 538-9.240-6.464 1.00 0.00 ATOM 680 1HB LYS+ 161 7.975-8.768-5.596 1.00 0.00 ATOM 681 2HB LYS+ 161 6.630-8.719-6.724 1.00 0.00 ATOM 682 QB LYS+ 161 7.302-8.743-6.160 1.00 0. 00 ATOM 683 CG LYS+ 161 8.519-9.118-7.620 1.00 0.00 ATOM 684 1HG LYS+ 161 9.210-9.949-7.584 1.00 0. 00 ATOM 685 2HG LYS+ 161 9.064-8.190-7.521 1.00 0.00 ATOM 686 QG LYS+ 161 9.137-9.069-7.552 1.00 0.00 ATOM 687 CD LYS+ 161 7.794-9.128-8.963 1.00 0.00 ATOM 688 1HD LYS+ 161 8.370-8.554-9.676 1.00 0.00 ATOM 689 2HD LYS+ 161 6.822-8.674-8.838 1.00 0.00 ATOM 690 QD LYS+ 161 7.596-8.614-9.257 1.00 0.00

ATOM 691 CE LYS+ 161 7.610-10.545-9.503 1.00 0.00 ATOM 692 1HE LYS+ 161 8.380-11.177-9.084 1.00 0.00 ATOM 693 2HE LYS+ 161 7.713-10.522-10.577 1.00 0.00 ATOM 694 QE LYS+ 161 8.046-10.849-9.830 1.00 0.00 ATOM 695 NZ LYS+ 161 6.276-11.113-9.159 1.00 0.00 ATOM 696 1HZ LYS+ 161 6.352-11.788-8.367 1.00 0.00 ATOM 697 2HZ LYS+ 161 5.866-11.609-9.976 1.00 0.00 ATOM 698 3HZ LYS+ 161 5.607-10.353-8.879 1.00 0.00 ATOM 699 QZ LYS+ 161 5.942-11.250-9.074 1.00 0.00 ATOM 700 C LYS+ 161 8.093-11.215-5.008 1.00 0.00 ATOM 701 O LYS+ 161 7.791-12.233-4.393 1.00 0.00 ATOM 702 N SER 162 9.192-10.537-4.756 1.00 0.00 ATOM 703 H SER 162 9.395-9.736-5.273 1.00 0.00 ATOM 704 CA SER 162 10.107-10.971-3.723 1.00 0.00 ATOM 705 HA SER 162 9.763-11.926-3.361 1.00 0.00 ATOM 706 CB SER 162 11.510-11.141-4.305 1.00 0.00 ATOM 707 1HB SER 162 11.838-12.160-4.153 1.00 0. 00 ATOM 708 2HB SER 162 12.188-10.468-3.799 1.00 0.00 ATOM 709 QB SER 162 12.013-11.314-3.976 1.00 0.00 ATOM 710 OG SER 162 11.528-10.853-5.700 1.00 0.00 ATOM 711 HG SER 162 12.368-11.138-6.071 1.00 0.00 ATOM 712 C SER 162 10.142-9.990-2.557 1.00 0.00 ATOM 713 O SER 162 11.214-9.591-2.119 1.00 0.00 ATOM 714 N THR 163 8.976-9.591-2.047 1.00 0.00 ATOM 715 H THR 163 8.132-9.929-2.427 1.00 0.00 ATOM 716 CA THR 163 8.943-8.661-0.920 1.00 0.00 ATOM 717 HA THR 163 9.867-8.790-0.369 1.00 0.00 ATOM 718 CB THR 163 8.860-7.205-1.386 1.00 0. 00 ATOM 719 HB THR 163 8.756-6.580-0.504 1.00 0.00 ATOM 720 QG2 THR 163 10.364-6.604-2.329 1.00 0.00 ATOM 721 OG1 THR 163 7.735-7.005-2.220 1.00 0.00 ATOM 722 1HG THR 163 7.515-7.832-2.671 1.00 0.00 ATOM 723 CG2 THR 163 10.074-6.719-2.148 1.00 0.00 ATOM 724 1HG2 THR 163 10.759-7.543-2.300 1.00 0.00 ATOM 725 2HG2 THR 163 10.566-5.942-1.582 1.00 0.00 ATOM 726 3HG2 THR 163 9.766-6.327-3.105 1.00 0.00 ATOM 727 C THR 163 7.780-8.951 0.029 1.00 0.00 ATOM 728 O THR 163 6.789-9.578-0.339 1.00 0.00 ATOM 729 N ASN 164 7.916-8.473 1.257 1.00 0.00 ATOM 730 H ASN 164 8.740-7.981 1.481 1.00 0.00 ATOM 731 CA ASN 164 6.891-8.654 2.291 1.00 0.00 ATOM 732 HA ASN 164 6.030-9.123 1.829 1.00 0.00 ATOM 733 CB ASN 164 7.416-9.555 3.419 1.00 0.00 ATOM 734 1HB ASN 164 7.231-10.587 3.161 1.00 0.00 ATOM 735 2HB ASN 164 6.894-9.320 4.335 1.00 0.00 ATOM 736 QB ASN 164 7.062-9.953 3.748 1.00 0.00 ATOM 737 CG ASN 164 8.907-9.385 3.662 1.00 0.00 ATOM 738 OD1 ASN 164 9.607-10.345 3.952 1.00 0.00 ATOM 739 ND2 ASN 164 9.392-8.155 3.564 1.00 0.00 ATOM 740 1HD2 ASN 164 8.766-7.428 3.364 1.00 0. 00 ATOM 741 2HD2 ASN 164 10.356-8.029 3.644 1.00 0.00 ATOM 742 QD2 ASN 164 9.561-7.728 3.504 1.00 0.00 ATOM 743 C ASN 164 6.472-7.308 2.880 1.00 0. 00 ATOM 744 O ASN 164 7.321-6.483 3.211 1.00 0.00 ATOM 745 N LEU 165 5.168-7.086 3.011 1.00 0.00 ATOM 746 H LEU 165 4.537-7.776 2.734 1.00 0.00 ATOM 747 CA LEU 165 4.656-5.832 3.565 1.00 0.00 ATOM 748 HA LEU 165 5.115-5.011 3.031 1.00 0.00 ATOM 749 CB LEU 165 3.141-5.742 3.407 1.00 0.00 ATOM 750 1HB LEU 165 2.704-5.613 4.385 1.00 0. 00 ATOM 751 2HB LEU 165 2.782-6.669 2.987 1.00 0.00 ATOM 752 QB LEU 165 2.743-6.141 3.686 1.00 0.00 ATOM 753 CG LEU 165 2.658-4.601 2.534 1.00 0.00 ATOM 754 HG LEU 165 3.161-3.690 2.827 1.00 0.00 ATOM 755 QD1 LEU 165 3.074-4.945 0.744 1.00 0.00 ATOM 756 QD2 LEU 165 0.810-4.349 2.757 1.00 0.00 ATOM 757 CD1 LEU 165 2.995-4.879 1.089 1.00 0.00 ATOM 758 1HD1 LEU 165 2.110-4.751 0.481 1.00 0.00 ATOM 759 2HD1 LEU 165 3.354-5.892 0.992 1.00 0.00 ATOM 760 3HD1 LEU 165 3.759-4.192 0.757 1.00 0.00 ATOM 761 CD2 LEU 165 1.165-4.397 2.714 1.00 0.00 ATOM 762 1HD2 LEU 165 0.632-5.224 2.267 1.00 0.00

ATOM 763 2HD2 LEU 165 0.867-3.476 2.235 1.00 0.00 ATOM 764 3HD2 LEU 165 0.932-4.346 3.768 1.00 0.00 ATOM 765 QQD LEU 165 1.942-4.647 1.750 1.00 0.00 ATOM 766 C LEU 165 5.002-5.699 5.034 1.00 0.00 ATOM 767 O LEU 165 4.671-6.566 5.840 1.00 0.00 ATOM 768 N HIS+ 166 5.651-4.603 5.370 1.00 0.00 ATOM 769 H HIS+ 166 5.876-3.945 4. 678 1.00 0.00 ATOM 770 CA HIS+ 166 6.029-4.333 6.740 1.00 0.00 ATOM 771 HA HIS+ 166 5.770-5.197 7.334 1.00 0.00 ATOM 772 CB HIS+ 166 7.540-4.093 6.833 1.00 0.00 ATOM 773 1HB HIS+ 166 7.791-3.213 6.257 1.00 0.00 ATOM 774 2HB HIS+ 166 8.059-4.945 6.423 1.00 0.00 ATOM 775 QB HIS+ 166 7.925-4.079 6.340 1.00 0.00 ATOM 776 CG HIS+ 166 8.034-3.885 8.230 1.00 0.00 ATOM 777 ND1 HIS+ 166 8.083-4.887 9.175 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.489-2.771 8.841 1.00 0.00 ATOM 779 1HD HIS+ 166 7.811-5.819 9.036 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.547-4.393 10.310 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.801-3.106 10.133 1.00 0.00 ATOM 782 2HD HIS+ 166 8.573-1.784 8.394 1.00 0.00 ATOM 783 1HE HIS+ 166 8.694-4.945 11.226 1.00 0.00 ATOM 784 2HE HIS+ 166 8.944-2.460 10.857 1.00 0.00 ATOM 785 C HIS+ 166 5.256-3.125 7.261 1.00 0.00 ATOM 786 O HIS+ 166 4.637-3.185 8.323 1.00 0.00 ATOM 787 N ASP 167 5.290-2.034 6.499 1.00 0.00 ATOM 788 H ASP 167 5.797-2.053 5.658 1.00 0.00 ATOM 789 CA ASP 167 4.589-0.810 6.888 1.00 0.00 ATOM 790 HA ASP 167 4.084-1.006 7.822 1.00 0.00 ATOM 791 CB ASP 167 5.571 0.353 7.092 1.00 0.00 ATOM 792 1HB ASP 167 5.158 1.034 7.822 1.00 0.00 ATOM 793 2HB ASP 167 5.692 0.874 6.155 1.00 0.00 ATOM 794 QB ASP 167 5.425 0.954 6.989 1.00 0.00 ATOM 795 CG ASP 167 6.940-0.085 7.569 1.00 0.00 ATOM 796 OD1 ASP 167 7.197-0.007 8.788 1.00 0.00 ATOM 797 OD2 ASP 167 7.760-0.507 6.723 1.00 0.00 ATOM 798 C ASP 167 3.551-0.407 5.844 1.00 0.00 ATOM 799 O ASP 167 3.860 0.291 4.882 1.00 0.00 ATOM 800 N TYR 168 2.322-0.855 6.036 1.00 0.00 ATOM 801 H TYR 168 2.139-1.409 6.824 1.00 0.00 ATOM 802 CA TYR 168 1.225-0.541 5.120 1.00 0.00 ATOM 803 HA TYR 168 1.646-0.339 4.137 1.00 0.00 ATOM 804 CB TYR 168 0.270-1.733 5.023 1.00 0.00 ATOM 805 1HB TYR 168 0.599-2.387 4.230 1.00 0.00 ATOM 806 2HB TYR 168-0.723-1.372 4.798 1.00 0.00 ATOM 807 QB TYR 168-0.062-1.879 4.514 1.00 0.00 ATOM 808 QD TYR 168 0.188-2.634 6.447 1.00 0.00 ATOM 809 QE TYR 168 0.080-3.930 8.531 1.00 0.00 ATOM 810 QR TYR 168 0.134-3.282 7. 489 1.00 0.00 ATOM 811 CG TYR 168 0.195-2.543 6.299 1.00 0.00 ATOM 812 CD1 TYR 168 1.032-3.633 6.506 1.00 0.00 ATOM 813 1HD TYR 168 1.737-3.907 5.736 1.00 0. 00 ATOM 814 CE1 TYR 168 0.974-4.363 7.675 1.00 0.00 ATOM 815 1HE TYR 168 1.634-5.207 7.818 1.00 0.00 ATOM 816 CZ TYR 168 0.073-4.009 8.657 1.00 0.00 ATOM 817 CE2 TYR 168-0.768-2.932 8.475 1.00 0.00 ATOM 818 2HE TYR 168-1.474-2.653 9.244 1.00 0.00 ATOM 819 CD2 TYR 168-0.703-2.206 7.303 1.00 0.00 ATOM 820 2HD TYR 168-1.360-1.361 7.157 1.00 0.00 ATOM 821 OH TYR 168 0.012-4.736 9.822 1.00 0.00 ATOM 822 HH TYR 168 0.750-4.494 10.390 1.00 0.00 ATOM 823 C TYR 168 0.455 0.693 5.583 1.00 0.00 ATOM 824 O TYR 168 0.288 0.921 6.781 1.00 0.00 ATOM 825 N GLY 169-0.034 1.463 4.627 1.00 0.00 ATOM 826 H GLY 169 0.115 1.217 3.690 1.00 0.00 ATOM 827 CA GLY 169-0.802 2.651 4.930 1.00 0.00 ATOM 828 1HA GLY 169-0.164 3.520 4.844 1.00 0.00 ATOM 829 2HA GLY 169-1.180 2.584 5.940 1.00 0.00 ATOM 830 QA GLY 169-0.672 3.052 5.392 1.00 0.00 ATOM 831 C GLY 169-1.955 2.788 3.968 1.00 0.00 ATOM 832 O GLY 169-1.917 2.218 2.878 1.00 0.00 ATOM 833 N MET 170-2.986 3.514 4.357 1.00 0.00 ATOM 834 H MET 170-2.970 3.937 5.241 1.00 0.00

ATOM 835 CA MET 170-4.150 3.691 3.500 1.00 0.00 ATOM 836 HA MET 170-3.850 3.471 2.479 1.00 0.00 ATOM 837 CB MET 170-5.276 2.736 3.916 1.00 0.00 ATOM 838 1HB MET 170-6.173 3.003 3.376 1.00 0.00 ATOM 839 2HB MET 170-5. 457 2.854 4.973 1.00 0.00 ATOM 840 QB MET 170-5.815 2.929 4.175 1.00 0.00 ATOM 841 CG MET 170-4.973 1.269 3.642 1.00 0.00 ATOM 842 1HG MET 170-4. 465 1.194 2.691 1.00 0.00 ATOM 843 2HG MET 170-5.904 0.725 3.594 1.00 0.00 ATOM 844 QG MET 170-5.185 0.960 3.143 1.00 0.00 ATOM 845 SD MET 170-3.931 0.525 4.914 1.00 0.00 ATOM 846 QE MET 170-4.108-1.561 4.434 1.00 0.00 ATOM 847 CE MET 170-4.078-1.211 4.514 1.00 0.00 ATOM 848 1HE MET 170-5.037-1.578 4.851 1.00 0.00 ATOM 849 2HE MET 170-3. 290-1.762 5.006 1.00 0.00 ATOM 850 3HE MET 170-3.997-1.343 3.445 1.00 0.00 ATOM 851 C MET 170-4.632 5.131 3.573 1.00 0.00 ATOM 852 O MET 170-5.049 5.603 4.631 1.00 0.00 ATOM 853 N LEU 171-4.555 5.830 2.452 1.00 0.00 ATOM 854 H LEU 171-4.205 5.399 1.644 1.00 0.00 ATOM 855 CA LEU 171-4.964 7.225 2.396 1.00 0.00 ATOM 856 HA LEU 171-5.163 7.547 3.407 1.00 0.00 ATOM 857 CB LEU 171-3.836 8.086 1.819 1.00 0.00 ATOM 858 1HB LEU 171-3.894 9.065 2.270 1.00 0.00 ATOM 859 2HB LEU 171-3. 998 8.189 0.754 1.00 0.00 ATOM 860 QB LEU 171-3.946 8.627 1.512 1.00 0.00 ATOM 861 CG LEU 171-2.425 7.541 2.041 1.00 0.00 ATOM 862 HG LEU 171-2.458 6. 761 2.788 1.00 0.00 ATOM 863 QD1 LEU 171-1. 749 6.799 0.453 1.00 0.00 ATOM 864 QD2 LEU 171-1.289 8.900 2.669 1.00 0.00 ATOM 865 CD1 LEU 171-1. 879 6.941 0.757 1.00 0.00 ATOM 866 1HD1 LEU 171-2.277 5.946 0.626 1.00 0.00 ATOM 867 2HD1 LEU 171-0.801 6.892 0.814 1.00 0.00 ATOM 868 3HD1 LEU 171-2.168 7.559-0.081 1.00 0.00 ATOM 869 CD2 LEU 171-1.507 8.641 2.548 1.00 0.00 ATOM 870 1HD2 LEU 171-1.498 9.456 1.841 1.00 0.00 ATOM 871 2HD2 LEU 171-0.506 8.248 2.661 1.00 0.00 ATOM 872 3HD2 LEU 171-1. 863 8.995 3.504 1.00 0.00 ATOM 873 QQD LEU 171-1.519 7.849 1.561 1.00 0.00 ATOM 874 C LEU 171-6.231 7.407 1.570 1.00 0.00 ATOM 875 O LEU 171-6.953 6.443 1.305 1.00 0.00 ATOM 876 N LEU 172-6.478 8.662 1.176 1.00 0.00 ATOM 877 H LEU 172-5.842 9.360 1.430 1.00 0.00 ATOM 878 CA LEU 172-7.646 9.050 0.380 1.00 0.00 ATOM 879 HA LEU 172-7.776 10.115 0.503 1.00 0.00 ATOM 880 CB LEU 172-7.408 8.764-1.105 1.00 0.00 ATOM 881 1HB LEU 172-8.255 8.208-1.480 1.00 0.00 ATOM 882 2HB LEU 172-6.525 8.146-1.199 1.00 0.00 ATOM 883 QB LEU 172-7.390 8.177-1.339 1.00 0.00 ATOM 884 CG LEU 172-7.226 10.005-1.981 1.00 0.00 ATOM 885 HG LEU 172-6.971 9.693-2.980 1.00 0.00 ATOM 886 QD1 LEU 172-8.824 10.988-2.067 1.00 0.00 ATOM 887 QD2 LEU 172-5. 826 11.082-1.334 1.00 0.00 ATOM 888 CD1 LEU 172-8.518 10.800-2.050 1.00 0.00 ATOM 889 1HD1 LEU 172-8.350 11.794-1.664 1.00 0.00 ATOM 890 2HD1 LEU 172-9.276 10.307-1.460 1.00 0.00 ATOM 891 3HD1 LEU 172-8.845 10.864-3.078 1.00 0.00 ATOM 892 CD2 LEU 172-6.095 10.877-1.458 1.00 0.00 ATOM 893 1HD2 LEU 172-5.221 10.264-1.282 1.00 0.00 ATOM 894 2HD2 LEU 172-6.398 11.346-0.534 1.00 0.00 ATOM 895 3HD2 LEU 172-5.860 11.636-2.188 1.00 0.00 ATOM 896 QQD LEU 172-7.325 11.035-1.701 1.00 0.00 ATOM 897 C LEU 172-8.929 8.358 0.848 1.00 0.00 ATOM 898 O LEU 172-9. 515 7.567 0.112 1.00 0. 00 ATOM 899 N PRO 173-9.394 8.648 2.076 1.00 0.00 ATOM 900 CD PRO 173-8.789 9.580 3.038 1.00 0.00 ATOM 901 CA PRO 173-10.616 8.044 2.609 1.00 0.00 ATOM 902 HA PRO 173-10.580 6.965 2.550 1.00 0. 00 ATOM 903 CB PRO 173-10.640 8.483 4.082 1.00 0.00 ATOM 904 1HB PRO 173-10.839 7.626 4.709 1.00 0.00 ATOM 905 2HB PRO 173-11.415 9.223 4.222 1.00 0. 00 ATOM 906 QB PRO 173-11.127 8.425 4.466 1.00 0. 00

ATOM 907 CG PRO 173-9.286 9.054 4.353 1.00 0.00 ATOM 908 1HG PRO 173-8.627 8.281 4.722 1.00 0.00 ATOM 909 2HG PRO 173-9.363 9.856 5.073 1.00 0.00 ATOM 910 QG PRO 173-8.995 9.069 4.898 1.00 0.00 ATOM 911 1HD PRO 173-7.711 9.538 2.992 1.00 0.00 ATOM 912 2HD PRO 173-9.140 10. 589 2.875 1.00 0.00 ATOM 913 QD PRO 173-8.426 10.064 2.934 1.00 0.00 ATOM 914 C PRO 173-11.859 8.549 1.883 1.00 0.00 ATOM 915 O PRO 173-12.200 9.728 1.967 1.00 0.00 ATOM 916 N CYS 174-12.527 7.658 1.167 1.00 0.00 ATOM 917 H CYS 174-12.208 6.732 1.133 1.00 0.00 ATOM 918 CA CYS 174-13.727 8.029 0.429 1.00 0.00 ATOM 919 HA CYS 174-13.687 9.094 0.252 1.00 0.00 ATOM 920 CB CYS 174-13.783 7.304-0.912 1.00 0.00 ATOM 921 1HB CYS 174-13.070 7.756-1.585 1.00 0.00 ATOM 922 2HB CYS 174-14.776 7.406-1.324 1.00 0.00 ATOM 923 QB CYS 174-13.923 7.581-1.454 1.00 0.00 ATOM 924 SG CYS 174-13.405 5.525-0.814 1.00 0.00 ATOM 925 C CYS 174-14.975 7.717 1.240 1.00 0.00 ATOM 926 O CYS 174-16. 002 8.377 1.099 1.00 0.00 ATOM 927 N GLY 175-14.876 6.713 2.097 1.00 0.00 ATOM 928 H GLY 175-14.026 6.224 2.174 1.00 0.00 ATOM 929 CA GLY 175-15.995 6.339 2.931 1.00 0.00 ATOM 930 1HA GLY 175-16.351 5.366 2.630 1.00 0.00 ATOM 931 2HA GLY 175-16. 787 7.063 2.807 1.00 0. 00 ATOM 932 QA GLY 175-16.569 6.215 2.719 1.00 0.00 ATOM 933 C GLY 175-15.593 6.290 4.384 1.00 0.00 ATOM 934 O GLY 175-14.449 6.590 4.717 1.00 0.00 ATOM 935 N ILE 176-16.521 5.904 5.247 1.00 0.00 ATOM 936 H ILE 176-17.413 5.670 4.920 1.00 0.00 ATOM 937 CA ILE 176-16.237 5.808 6.673 1.00 0.00 ATOM 938 HA ILE 176-15.835 6.755 7.003 1.00 0.00 ATOM 939 CB ILE 176-17.513 5.499 7.488 1.00 0.00 ATOM 940 HB ILE 176-17.558 4.431 7.642 1.00 0.00 ATOM 941 QG2 ILE 176-17.438 6.328 9.175 1.00 0.00 ATOM 942 CG2 ILE 176-17.452 6.170 8.852 1.00 0.00 ATOM 943 1HG2 ILE 176-17.431 7.242 8.725 1.00 0.00 ATOM 944 2HG2 ILE 176-16.560 5.851 9.371 1.00 0.00 ATOM 945 3HG2 ILE 176-18.323 5.892 9.428 1.00 0.00 ATOM 946 CG1 ILE 176-18.766 5.948 6.733 1.00 0.00 ATOM 947 1HG1 ILE 176-18.760 5.512 5.745 1.00 0.00 ATOM 948 2HG1 ILE 176-18.761 7.025 6.648 1.00 0.00 ATOM 949 QG1 ILE 176-18.761 6.269 6.197 1.00 0.00 ATOM 950 QD1 ILE 176-20.362 5.447 7.575 1.00 0.00 ATOM 951 CD1 ILE 176-20.056 5.544 7.412 1.00 0.00 ATOM 952 1HD1 ILE 176-20.875 6.112 6.999 1.00 0.00 ATOM 953 2HD1 ILE 176-19.979 5.739 8.472 1.00 0.00 ATOM 954 3HD1 ILE 176-20.231 4.490 7.253 1.00 0.00 ATOM 955 C ILE 176-15.205 4.711 6.928 1.00 0.00 ATOM 956 O ILE 176-14.322 4.850 7.774 1.00 0.00 ATOM 957 N ASP 177-15.330 3.622 6.177 1.00 0.00 ATOM 958 H ASP 177-16.057 3.579 5.522 1.00 0.00 ATOM 959 CA ASP 177-14.423 2.487 6.293 1.00 0.00 ATOM 960 HA ASP 177-13.659 2.741 7.012 1.00 0.00 ATOM 961 CB ASP 177-15.189 1.250 6.783 1.00 0.00 ATOM 962 1HB ASP 177-15.874 1.543 7.564 1.00 0.00 ATOM 963 2HB ASP 177-14.486 0.533 7.178 1.00 0.00 ATOM 964 QB ASP 177-15.180 1.038 7.371 1.00 0.00 ATOM 965 CG ASP 177-15.981 0.581 5.676 1.00 0.00 ATOM 966 OD1 ASP 177-15.849-0.647 5.507 1.00 0.00 ATOM 967 OD2 ASP 177-16.716 1.285 4.954 1.00 0.00 ATOM 968 C ASP 177-13.767 2.183 4.947 1.00 0.00 ATOM 969 0 ASP 177-13.109 1.153 4.776 1.00 0. 00 ATOM 970 N LYS+ 178-13.968 3.071 3.981 1.00 0.00 ATOM 971 H LYS+ 178-14.509 3.864 4.167 1.00 0. 00 ATOM 972 CA LYS+ 178-13.416 2.877 2.646 1.00 0.00 ATOM 973 HA LYS+ 178-12.956 1.901 2.618 1.00 0.00 ATOM 974 CB LYS+ 178-14.532 2.929 1.601 1.00 0.00 ATOM 975 1HB LYS+ 178-14.154 2.538 0.670 1.00 0. 00 ATOM 976 2HB LYS+ 178-14.819 3.960 1.455 1.00 0.00 ATOM 977 QB LYS+ 178-14.487 3.249 1.063 1.00 0. 00 ATOM 978 CG LYS+ 178-15.772 2.135 1.993 1.00 0. 00

ATOM 979 1HG LYS+ 178-16.617 2.806 2.046 1.00 0.00 ATOM 980 2HG LYS+ 178-15.608 1.688 2.964 1.00 0.00 ATOM 981 QG LYS+ 178-16. 113 2.247 2.505 1.00 0.00 ATOM 982 CD LYS+ 178-16.079 1.029 0.992 1.00 0.00 ATOM 983 1HD LYS+ 178-15. 308 1.017 0.234 1.00 0.00 ATOM 984 2HD LYS+ 178-17. 034 1.233 0.528 1.00 0.00 ATOM 985 QD LYS+ 178-16.171 1.125 0.381 1.00 0.00 ATOM 986 CE LYS+ 178-16. 138-0. 342 1.659 1.00 0.00 ATOM 987 1HE LYS+ 178-15.827-1.089 0. 942 1.00 0.00 ATOM 988 2HE LYS+ 178-17. 157-0. 539 1.961 1.00 0.00 ATOM 989 QE LYS+ 178-16.492-0.814 1.452 1.00 0.00 ATOM 990 NZ LYS+ 178-15. 255-0.423 2.858 1.00 0.00 ATOM 991 1HZ LYS+ 178-14. 511 0.298 2.809 1.00 0.00 ATOM 992 2HZ LYS+ 178-14. 805-1. 365 2.914 1.00 0.00 ATOM 993 3HZ LYS+ 178-15.812-0.271 3.736 1.00 0.00 ATOM 994 QZ LYS+ 178-15.043-0.446 3.153 1.00 0.00 ATOM 995 C LYS+ 178-12. 352 3.906 2.317 1.00 0.00 ATOM 996 O LYS+ 178-12.503 5.094 2.596 1.00 0.00 ATOM 997 N PHE 179-11.280 3.432 1.703 1.00 0.00 ATOM 998 H PHE 179-11.234 2.476 1.497 1.00 0.00 ATOM 999 CA PHE 179-10. 175 4.286 1.313 1.00 0.00 ATOM 1000 HA PHE 179-10.446 5.309 1.524 1.00 0.00 ATOM 1001 CB PHE 179-8.911 3.929 2.090 1.00 0.00 ATOM 1002 1HB PHE 179-8. 227 4.744 2.010 1.00 0.00 ATOM 1003 2HB PHE 179-8.456 3.058 1.648 1.00 0.00 ATOM 1004 QB PHE 179-8.342 3.901 1.829 1.00 0.00 ATOM 1005 QD PHE 179-9.163 3.622 3.710 1.00 0.00 ATOM 1006 QE PHE 179-9.534 3.173 6.099 1.00 0.00 ATOM 1007 QR PHE 179-9. 423 3.307 5.383 1.00 0.00 ATOM 1008 CG PHE 179-9. 137 3.653 3.549 1.00 0.00 ATOM 1009 CD1 PHE 179-9.194 4.692 4.462 1.00 0.00 ATOM 1010 1HD PHE 179-9. 074 5.709 4.117 1.00 0.00 ATOM 1011 CE1 PHE 179-9.402 4.442 5.804 1.00 0.00 ATOM 1012 1HE PHE 179-9.445 5.262 6. 507 1.00 0.00 ATOM 1013 CZ PHE 179-9.557 3.144 6.247 1.00 0.00 ATOM 1014 HZ PHE 179-9.721 2.947 7.296 1.00 0.00 ATOM 1015 CE2 PHE 179-9.502 2.099 5.346 1.00 0.00 ATOM 1016 2HE PHE 179-9.623 1.083 5.690 1.00 0.00 ATOM 1017 CD2 PHE 179-9. 294 2.354 4.006 1.00 0.00 ATOM 1018 2HD PHE 179-9.252 1.535 3.302 1.00 0.00 ATOM 1019 C PHE 179-9.894 4.139-0.166 1.00 0.00 ATOM 1020 O PHE 179-10. 564 3.376-0.862 1.00 0.00 ATOM 1021 N ARG+ 180-8.886 4.854-0.634 1.00 0.00 ATOM 1022 H ARG+ 180-8.384 5.431-0.018 1.00 0.00 ATOM 1023 CA ARG+ 180-8.488 4.795-2.030 1.00 0.00 ATOM 1024 HA ARG+ 180-8.928 3.912-2.471 1.00 0.00 ATOM 1025 CB ARG+ 180-8.979 6.031-2.794 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.837 5.857-3.851 1.00 0.00 ATOM 1027 2HB ARG+ 180-8. 380 6.879-2.504 1.00 0.00 ATOM 1028 QB ARG+ 180-8.609 6.368-3.177 1.00 0. 00 ATOM 1029 CG ARG+ 180-10.439 6.376-2.560 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.520 6.937-1.639 1.00 0.00 ATOM 1031 2HG ARG+ 180-11. 006 5.460-2.477 1.00 0.00 ATOM 1032 QG ARG+ 180-10.763 6.199-2.058 1.00 0.00 ATOM 1033 CD ARG+ 180-11. 004 7.208-3.699 1.00 0.00 ATOM 1034 1HD ARG+ 180-10. 198 7.772-4.148 1.00 0.00 ATOM 1035 2HD ARG+ 180-11.738 7.889-3.298 1.00 0.00 ATOM 1036 QD ARG+ 180-10.968 7.831-3.723 1.00 0.00 ATOM 1037 NE ARG+ 180-11.634 6.378-4.726 1.00 0.00 ATOM 1038 HE ARG+ 180-11.417 5.414-4.727 1.00 0.00 ATOM 1039 CZ ARG+ 180-12. 477 6.852-5.645 1.00 0.00 ATOM 1040 NH1 ARG+ 180-12. 757 8.151-5.679 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.335 8.771-5.017 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.381 8.513-6.372 1.00 0.00 ATOM 1043 QH1 ARG+ 180-12.858 8.642-5.694 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.023 6.037-6.539 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.805 5.056-6.529 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.643 6.396-7.237 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13.224 5.726-6.883 1.00 0.00 ATOM 1048 C ARG+ 180-6.972 4. 708-2.154 1.00 0.00 ATOM 1049 0 ARG+ 180-6.456 4.235-3.154 1.00 0.00 ATOM 1050 N GLY 181-6.255 5.180-1.146 1.00 0.00

ATOM 1051 H GLY 181-6.705 5.556-0.358 1.00 0.00 ATOM 1052 CA GLY 181-4.807 5.157-1.217 1.00 0.00 ATOM 1053 1HA GLY 181-4.430 6.113-0.878 1.00 0.00 ATOM 1054 2HA GLY 181-4.518 5.020-2.248 1.00 0.00 ATOM 1055 QA GLY 181-4.474 5.567-1.563 1.00 0.00 ATOM 1056 C GLY 181-4.173 4.064-0.394 1.00 0.00 ATOM 1057 O GLY 181-4. 746 3.600 0.591 1.00 0. 00 ATOM 1058 N VAL 182-2.975 3.661-0. 802 1.00 0.00 ATOM 1059 H VAL 182-2.578 4.086-1.590 1.00 0.00 ATOM 1060 CA VAL 182-2.219 2.624-0.111 1. 00 0.00 ATOM 1061 HA VAL 182-2.541 2.604 0.924 1.00 0.00 ATOM 1062 CB VAL 182-2.432 1.214-0.725 1.00 0.00 ATOM 1063 HB VAL 182-1.642 1.041-1.443 1.00 0.00 ATOM 1064 QG1 VAL 182-2.301-0.107 0.606 1.00 0.00 ATOM 1065 QG2 VAL 182-4.082 1.073-1.622 1.00 0.00 ATOM 1066 CG1 VAL 182-2.326 0.146 0.351 1.00 0.00 ATOM 1067 1HG1 VAL 182-1.438-0.446 0.185 1.00 0.00 ATOM 1068 2HG1 VAL 182-3.197-0.492 0.310 1.00 0.00 ATOM 1069 3HG1 VAL 182-2.269 0.617 1.322 1.00 0.00 ATOM 1070 CG2 VAL 182-3.766 1.100-1.451 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.672 1.511-2.445 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.521 1.648-0.906 1.00 0.00 ATOM 1073 3HG2 VAL 182-4.053 0.061-1.516 1.00 0.00 ATOM 1074 QQG VAL 182-3.192 0.483-0.508 1.00 0.00 ATOM 1075 C VAL 182-0.726 2.955-0.156 1.00 0.00 ATOM 1076 O VAL 182-0.175 3.228-1. 223 1.00 0.00 ATOM 1077 N GLU 183-0.086 2.930 1.006 1.00 0.00 ATOM 1078 H GLU 183-0.592 2.707 1.819 1.00 0.00 ATOM 1079 CA GLU 183 1.342 3.223 1.123 1.00 0.00 ATOM 1080 HA GLU 183 1.764 3.258 0.128 1.00 0.00 ATOM 1081 CB GLU 183 1.552 4.573 1.815 1.00 0.00 ATOM 1082 1HB GLU 183 1.792 5.315 1.068 1.00 0.00 ATOM 1083 2HB GLU 183 2.383 4.487 2.501 1.00 0.00 ATOM 1084 QB GLU 183 2.087 4.901 1.785 1.00 0.00 ATOM 1085 CG GLU 183 0.344 5.059 2.599 1.00 0.00 ATOM 1086 1HG GLU 183-0.136 4.209 3.059 1.00 0.00 ATOM 1087 2HG GLU 183-0.345 5.534 1.917 1.00 0.00 ATOM 1088 QG GLU 183-0.241 4.872 2.488 1.00 0.00 ATOM 1089 CD GLU 183 0.709 6.050 3.680 1.00 0.00 ATOM 1090 OE1 GLU 183 0.054 6.033 4.740 1.00 0.00 ATOM 1091 OE2 GLU 183 1.646 6.845 3.462 1.00 0.00 ATOM 1092 C GLU 183 2.028 2.121 1.922 1.00 0.00 ATOM 1093 O GLU 183 2.060 2.158 3.145 1.00 0.00 ATOM 1094 N PHE 184 2.539 1.120 1.234 1.00 0.00 ATOM 1095 H PHE 184 2.463 1.122 0.262 1.00 0.00 ATOM 1096 CA PHE 184 3.167-0.013 1.902 1.00 0.00 ATOM 1097 HA PHE 184 3.038 0.130 2.962 1.00 0.00 ATOM 1098 CB PHE 184 2.466-1.314 1.499 1.00 0.00 ATOM 1099 1HB PHE 184 1.579-1.440 2.103 1.00 0.00 ATOM 1100 2HB PHE 184 3.134-2.145 1.688 1.00 0.00 ATOM 1101 QB PHE 184 2.356-1.792 1.896 1.00 0.00 ATOM 1102 QD PHE 184 2.006-1.385-0.119 1.00 0.00 ATOM 1103 QE PHE 184 1.312-1.540-2.470 1.00 0.00 ATOM 1104 QR PHE 184 1.519-1.496-1.764 1.00 0.00 ATOM 1105 CG PHE 184 2.054-1.379 0.047 1.00 0.00 ATOM 1106 CD1 PHE 184 2.702-2.231-0. 830 1.00 0.00 ATOM 1107 1HD PHE 184 3.522-2.835-0. 471 1.00 0.00 ATOM 1108 CE1 PHE 184 2.312-2.323-2.150 1.00 0.00 ATOM 1109 1HE PHE 184 2.828-2.994-2.820 1.00 0.00 ATOM 1110 CZ PHE 184 1.268-1.553-2.615 1.00 0.00 ATOM 1111 HZ PHE 184 0.957-1.630-3. 645 1.00 0.00 ATOM 1112 CE2 PHE 184 0.614-0.693-1.759 1.00 0.00 ATOM 1113 2HE PHE 184-0.204-0.087-2.121 1.00 0.00 ATOM 1114 CD2 PHE 184 1.003-0.610-0. 436 1.00 0.00 ATOM 1115 2HD PHE 184 0.490 0.065 0.233 1.00 0.00 ATOM 1116 C PHE 184 4.653-0.131 1.609 1.00 0.00 ATOM 1117 O PHE 184 5.093 0.030 0.477 1.00 0.00 ATOM 1118 N VAL 185 5.413-0.445 2.648 1.00 0.00 ATOM 1119 H VAL 185 4.990-0.576 3.524 1.00 0.00 ATOM 1120 CA VAL 185 6.849-0.623 2.530 1.00 0.00 ATOM 1121 HA VAL 185 7.156-0.287 1.549 1.00 0.00 ATOM 1122 CB VAL 185 7.612 0.192 3.603 1.00 0.00

ATOM 1123 HB VAL 185 7.788-0.451 4.458 1.00 0.00 ATOM 1124 QG1 VAL 185 9.275 0.770 2.957 1.00 0.00 ATOM 1125 QG2 VAL 185 6.604 1.668 4.187 1.00 0.00 ATOM 1126 CG1 VAL 185 8.957 0. 658 3.080 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.720 0.437 3.810 1.00 0.00 ATOM 1128 2HG1 VAL 185 8. 923 1.724 2.906 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.182 0.149 2.155 1.00 0.00 ATOM 1130 CG2 VAL 185 6.797 1.386 4.073 1.00 0.00 ATOM 1131 1HG2 VAL 185 5.744 1.152 4.009 1.00 0.00 ATOM 1132 2HG2 VAL 185 7.015 2.241 3.451 1.00 0.00 ATOM 1133 3HG2 VAL 185 7.053 1.612 5.099 1.00 0.00 ATOM 1134 QQG VAL 185 7.939 1.219 3.572 1.00 0.00 ATOM 1135 C VAL 185 7.180-2.108 2.675 1.00 0.00 ATOM 1136 O VAL 185 7.100-2.669 3.766 1.00 0.00 ATOM 1137 N CYS 186 7.520-2.753 1.568 1.00 0.00 ATOM 1138 H CYS 186 7.547-2.263 0.714 1.00 0. 00 ATOM 1139 CA CYS 186 7. 834-4.176 1.590 1.00 0.00 ATOM 1140 HA CYS 186 7.625-4.539 2.588 1.00 0.00 ATOM 1141 CB CYS 186 6.946-4.943 0.598 1.00 0.00 ATOM 1142 1HB CYS 186 5.954-5.029 1.017 1.00 0.00 ATOM 1143 2HB CYS 186 7.354-5.930 0.459 1.00 0.00 ATOM 1144 QB CYS 186 6. 654-5.479 0.738 1.00 0.00 ATOM 1145 SG CYS 186 6.784-4.189-1.050 1.00 0.00 ATOM 1146 C CYS 186 9. 311-4.419 1.287 1.00 0.00 ATOM 1147 O CYS 186 9.834-3.929 0.295 1.00 0.00 ATOM 1148 N CYS 187 9.984-5.180 2.141 1.00 0.00 ATOM 1149 H CYS 187 9.520-5.556 2.920 1.00 0. 00 ATOM 1150 CA CYS 187 11.407-5.466 1.942 1.00 0.00 ATOM 1151 HA CYS 187 11.830-4.651 1.374 1.00 0.00 ATOM 1152 CB CYS 187 12.141-5.570 3.283 1.00 0.00 ATOM 1153 1HB CYS 187 12.938-6.293 3.189 1.00 0.00 ATOM 1154 2HB CYS 187 11.447-5.906 4.039 1.00 0.00 ATOM 1155 QB CYS 187 12.192-6.099 3.614 1.00 0.00 ATOM 1156 SG CYS 187 12.875-4.005 3.858 1.00 0.00 ATOM 1157 C CYS 187 11. 601-6. 753 1.163 1.00 0.00 ATOM 1158 O CYS 187 10.736-7.624 1.188 1.00 0.00 ATOM 1159 N PRO 188 12.734-6.882 0.446 1.00 0.00 ATOM 1160 CD PRO 188 13.811-5.875 0.349 1.00 0.00 ATOM 1161 CA PRO 188 13.025-8.074-0.354 1.00 0.00 ATOM 1162 HA PRO 188 12.244-8.259-1.078 1.00 0. 00 ATOM 1163 CB PRO 188 14.325-7.724-1.087 1.00 0. 00 ATOM 1164 1HB PRO 188 14.097-7.400-2.091 1.00 0.00 ATOM 1165 2HB PRO 188 14.963-8.595-1.121 1.00 0.00 ATOM 1166 QB PRO 188 14.530-7.997-1.606 1.00 0.00 ATOM 1167 CG PRO 188 14.945-6.628-0.290 1.00 0.00 ATOM 1168 1HG PRO 188 15.509-5.975-0.941 1.00 0.00 ATOM 1169 2HG PRO 188 15.590-7.048 0.468 1.00 0. 00 ATOM 1170 QG PRO 188 15.549-6.511-0.236 1.00 0.00 ATOM 1171 1HD PRO 188 13.510-5.045-0.275 1.00 0.00 ATOM 1172 2HD PRO 188 14.101-5.523 1.328 1.00 0.00 ATOM 1173 QD PRO 188 13.805-5.284 0.527 1.00 0.00 ATOM 1174 C PRO 188 13.214-9.325 0.501 1.00 0.00 ATOM 1175 O PRO 188 13.995-9.325 1.456 1.00 0.00 ATOM 1176 N LEU 189 12.495-10.378 0.139 1.00 0.00 ATOM 1177 H LEU 189 11.898-10.301-0.636 1.00 0.00 ATOM 1178 CA LEU 189 12.566-11.649 0.839 1.00 0.00 ATOM 1179 HA LEU 189 13.381-11.598 1.546 1.00 0. 00 ATOM 1180 CB LEU 189 11.260-11.926 1. 589 1. 00 0. 00 ATOM 1181 1HB LEU 189 10.489-12.121 0.860 1.00 0.00 ATOM 1182 2HB LEU 189 10.993-11.038 2.143 1.00 0.00 ATOM 1183 QB LEU 189 10.741-11.579 1.502 1.00 0. 00 ATOM 1184 CG LEU 189 11.307-13.106 2.562 1.00 0. 00 ATOM 1185 HG LEU 189 11.883-13.906 2.118 1.00 0.00 ATOM 1186 QD1 LEU 189 12.144-12.608 4.169 1.00 0. 00 ATOM 1187 QD2 LEU 189 9.574-13.749 2.899 1.00 0.00 ATOM 1188 CD1 LEU 189 11.984-12.703 3.862 1. oxo 0. 00 ATOM 1189 1HD1 LEU 189 12.023-13.554 4.525 1.00 0. 00 ATOM 1190 2HD1 LEU 189 11.422-11.907 4.328 1. 00 0. 00 ATOM 1191 3HD1 LEU 189 12.987-12.362 3.653 1. 00 0. 00 ATOM 1192 CD2 LEU 189 9.905-13.626 2.834 1. 00 0.00 ATOM 1193 1HD2 LEU 189 9.462-13.964 1.909 1. 00 0. 00 ATOM 1194 2HD2 LEU 189 9.304-12.834 3.255 1. 00 0. 00

ATOM 1195 3HD2 LEU 189 9.957-14.449 3.531 1.00 0.00 ATOM 1196 QQD LEU 189 10.859-13.178 3.534 1.00 0.00 ATOM 1197 C LEU 189 12.840-12.772-0.157 1.00 0.00 ATOM 1198 OT1 LEU 189 13.449-13.786 0.241 1.00 0.00 ATOM 1199 OT2 LEU 189 12.444-12.622-1.334 1.00 0.00 TER ENDMDL MODEL 14 ATOM 1 N SER 124 10.923 13.144 3.020 1.00 0.00 ATOM 2 CA SER 124 10.433 13.935 1.863 1.00 0.00 ATOM 3 HA SER 124 9.561 13.451 1.449 1.00 0.00 ATOM 4 CB SER 124 10. 059 15.328 2.369 1.00 0.00 ATOM 5 1HB SER 124 9.109 15.622 1.948 1.00 0.00 ATOM 6 2HB SER 124 10.823 16.033 2.068 1.00 0.00 ATOM 7 QB SER 124 9.966 15.827 2.008 1.00 0.00 ATOM 8 OG SER 124 9.958 15.336 3.788 1.00 0.00 ATOM 9 HG SER 124 9.824 16.241 4.096 1.00 0.00 ATOM 10 C SER 124 11.515 14.022 0.805 1.00 0.00 ATOM 11 O SER 124 11.892 15.105 0.361 1.00 0.00 ATOM 12 1HT SER 124 11.929 12.890 2.881 1.00 0.00 ATOM 13 2HT SER 124 10.368 12.273 3.123 1.00 0.00 ATOM 14 3HT SER 124 10.838 13.705 3.892 1.00 0.00 ATOM 15 N ASP 125 12.027 12. 862 0.446 1.00 0.00 ATOM 16 H ASP 125 11.689 12.045 0.868 1.00 0.00 ATOM 17 CA ASP 125 13.100 12.743-0.520 1.00 0.00 ATOM 18 HA ASP 125 13.320 13.725-0.912 1.00 0.00 ATOM 19 CB ASP 125 14.336 12.181 0.189 1.00 0.00 ATOM 20 1HB ASP 125 14. 998 12.994 0.453 1.00 0.00 ATOM 21 2HB ASP 125 14.850 11.502-0.476 1.00 0.00 ATOM 22 QB ASP 125 14.924 12.248-0.012 1.00 0.00 ATOM 23 CG ASP 125 13.964 11.429 1.455 1.00 0.00 ATOM 24 OD1 ASP 125 13.952 10.186 1.419 1.00 0.00 ATOM 25 OD2 ASP 125 13.640 12.087 2.474 1.00 0.00 ATOM 26 C ASP 125 12.673 11.823-1.652 1.00 0.00 ATOM 27 O ASP 125 12.281 12.277-2.725 1.00 0.00 ATOM 28 N ALA 126 12.729 10.526-1.393 1.00 0.00 ATOM 29 H ALA 126 13.036 10.228-0.507 1.00 0.00 ATOM 30 CA ALA 126 12.327 9.538-2.377 1.00 0.00 ATOM 31 HA ALA 126 12.505 9.952-3.359 1.00 0.00 ATOM 32 QB ALA 126 13.353 7.971-2.195 1.00 0.00 ATOM 33 CB ALA 126 13.157 8.271-2.231 1.00 0.00 ATOM 34 1HB ALA 126 12.621 7.557-1.621 1.00 0.00 ATOM 35 2HB ALA 126 14. 099 8.510-1.759 1.00 0.00 ATOM 36 3HB ALA 126 13.340 7.845-3.206 1.00 0.00 ATOM 37 C ALA 126 10.846 9.222-2.229 1.00 0.00 ATOM 38 O ALA 126 10.296 9.283-1.130 1.00 0.00 ATOM 39 N LEU 127 10.203 8.884-3.336 1.00 0.00 ATOM 40 H LEU 127 10.691 8.851-4.181 1.00 0.00 ATOM 41 CA LEU 127 8.785 8.556-3.319 1.00 0.00 ATOM 42 HA LEU 127 8.367 8.949-2.406 1.00 0.00 ATOM 43 CB LEU 127 8.074 9.195-4.512 1.00 0.00 ATOM 44 1HB LEU 127 8.117 8.501-5.338 1.00 0.00 ATOM 45 2HB LEU 127 8. 609 10.092-4.787 1.00 0.00 ATOM 46 QB LEU 127 8.363 9.296-5.063 1.00 0.00 ATOM 47 CG LEU 127 6.608 9.560-4.271 1.00 0.00 ATOM 48 HG LEU 127 6.256 9.044-3.389 1.00 0.00 ATOM 49 QD1 LEU 127 6.424 11.407-3.974 1.00 0.00 ATOM 50 QD2 LEU 127 5.544 9.019-5.723 1.00 0.00 ATOM 51 CD1 LEU 127 6.460 11.053-4.031 1.00 0.00 ATOM 52 1HD1 LEU 127 7.403 11.545-4.219 1.00 0.00 ATOM 53 2HD1 LEU 127 6.163 11.224-3.007 1.00 0.00 ATOM 54 3HD1 LEU 127 5.708 11.451-4.695 1.00 0.00 ATOM 55 CD2 LEU 127 5.749 9.122-5.446 1.00 0.00 ATOM 56 1HD2 LEU 127 4.709 9.306-5.218 1.00 0.00 ATOM 57 2HD2 LEU 127 5.897 8.068-5.626 1.00 0.00 ATOM 58 3HD2 LEU 127 6.028 9.682-6.326 1.00 0.00 ATOM 59 QQD LEU 127 5.984 10.213-4.849 1.00 0.00 ATOM 60 C LEU 127 8.587 7.047-3.344 1.00 0.00 ATOM 61 O LEU 127 7.484 6.554-3.577 1.00 0.00 ATOM 62 N LEU 128 9.666 6.317-3.109 1.00 0.00 ATOM 63 H LEU 128 10.516 6.765-2.934 1.00 0.00 ATOM 64 CA LEU 128 9.616 4.869-3.109 1.00 0.00

ATOM 65 HA LEU 128 8.609 4.567-2.900 1.00 0.00 ATOM 66 CB LEU 128 10.015 4.338-4.490 1.00 0.00 ATOM 67 1HB LEU 128 11.076 4.144-4.483 1.00 0.00 ATOM 68 2HB LEU 128 9.812 5.109-5.220 1.00 0.00 ATOM 69 QB LEU 128 10.444 4.626-4.852 1.00 0.00 ATOM 70 CG LEU 128 9.292 3.060-4.927 1.00 0.00 ATOM 71 HG LEU 128 8.843 2.591-4.062 1.00 0.00 ATOM 72 QD1 LEU 128 7.913 3.473-6.135 1.00 0. 00 ATOM 73 QD2 LEU 128 10.495 1.845-5.705 1.00 0.00 ATOM 74 CD1 LEU 128 8.178 3.394-5.903 1.00 0.00 ATOM 75 1HD1 LEU 128 7.451 2.595-5.909 1.00 0.00 ATOM 76 2HD1 LEU 128 8.591 3.511-6.895 1.00 0.00 ATOM 77 3HD1 LEU 128 7.698 4.314-5.602 1.00 0.00 ATOM 78 CD2 LEU 128 10.265 2.078-5.555 1.00 0.00 ATOM 79 1HD2 LEU 128 10. 566 1.347-4.819 1.00 0.00 ATOM 80 2HD2 LEU 128 11.135 2.610-5.911 1.00 0.00 ATOM 81 3HD2 LEU 128 9.786 1.578-6.384 1.00 0.00 ATOM 82 QQD LEU 128 9.204 2.659-5.920 1.00 0.00 ATOM 83 C LEU 128 10.519 4.318-2.012 1.00 0.00 ATOM 84 O LEU 128 10.430 4.742-0.864 1.00 0.00 ATOM 85 N VAL 129 11.370 3.376-2.376 1.00 0.00 ATOM 86 H VAL 129 11.365 3.093-3.308 1.00 0.00 ATOM 87 CA VAL 129 12.308 2.742-1.438 1.00 0. 00 ATOM 88 HA VAL 129 11.737 2.165-0.727 1.00 0.00 ATOM 89 CB VAL 129 13.272 1.786-2.180 1.00 0.00 ATOM 90 HB VAL 129 13.966 2.389-2.751 1.00 0.00 ATOM 91 QG1 VAL 129 14.272 0.753-0.968 1.00 0.00 ATOM 92 QG2 VAL 129 12.341 0.677-3.377 1.00 0.00 ATOM 93 CG1 VAL 129 14.080 0.950-1.200 1.00 0.00 ATOM 94 1HG1 VAL 129 13.462 0.687-0.355 1.00 0.00 ATOM 95 2HG1 VAL 129 14.933 1.520-0.858 1.00 0.00 ATOM 96 3HG1 VAL 129 14.422 0.051-1.691 1.00 0. 00 ATOM 97 CG2 VAL 129 12.519 0.890-3.148 1.00 0.00 ATOM 98 1HG2 VAL 129 13.001-0.076-3.191 1.00 0.00 ATOM 99 2HG2 VAL 129 12.523 1.338-4.130 1.00 0.00 ATOM 100 3HG2 VAL 129 11.501 0.770-2.809 1.00 0.00 ATOM 101 QQG VAL 129 13.307 0.715-2.172 1.00 0.00 ATOM 102 C VAL 129 13.154 3.775-0.682 1.00 0.00 ATOM 103 O VAL 129 14.029 4. 409-1.270 1.00 0.00 ATOM 104 N PRO 130 12.910 3.957 0.635 1.00 0.00 ATOM 105 CD PRO 130 11.898 3.273 1.438 1.00 0.00 ATOM 106 CA PRO 130 13. 656 4.896 1.459 1.00 0.00 ATOM 107 HA PRO 130 13.924 5.777 0.914 1.00 0.00 ATOM 108 CB PRO 130 12.664 5.261 2.579 1.00 0.00 ATOM 109 1HB PRO 130 12.369 6.294 2.470 1.00 0.00 ATOM 110 2HB PRO 130 13.141 5.122 3.537 1.00 0.00 ATOM 111 QB PRO 130 12.755 5.708 3.003 1.00 0.00 ATOM 112 CG PRO 130 11.487 4. 340 2.417 1.00 0.00 ATOM 113 1HG PRO 130 10.643 4.894 2.031 1.00 0.00 ATOM 114 2HG PRO 130 11.237 3.896 3.369 1.00 0. 00 ATOM 115 QG PRO 130 10.940 4. 395 2.700 1.00 0.00 ATOM 116 1HD PRO 130 11.060 2.966 0.832 1.00 0.00 ATOM 117 2HD PRO 130 12.324 2.424 1.956 1.00 0. 00 ATOM 118 QD PRO 130 11.692 2.695 1.394 1.00 0. 00 ATOM 119 C PRO 130 14. 917 4. 266 2.041 1.00 0. 00 ATOM 120 O PRO 130 16.023 4.476 1.549 1.00 0. 00 ATOM 121 N ASP 131 14.719 3.491 3.094 1.00 0.00 ATOM 122 H ASP 131 13.809 3.382 3. 415 1.00 0.00 ATOM 123 CA ASP 131 15.810 2.800 3.780 1.00 0.00 ATOM 124 HA ASP 131 16. 688 3.428 3. 724 1.00 0. 00 ATOM 125 CB ASP 131 15.440 2.585 5.256 1.00 0.00 ATOM 126 1HB ASP 131 14.546 1.984 5. 312 1.00 0.00 ATOM 127 2HB ASP 131 15.252 3.543 5.715 1.00 0.00 ATOM 128 QB ASP 131 14.899 2.763 5.513 1. 00 0. 00 ATOM 129 CG ASP 131 16.532 1.891 6.044 1. 00 0.00 ATOM 130 OD1 ASP 131 16.303 0.743 6.478 1. 00 0. 00 ATOM 131 OD2 ASP 131 17.608 2.492 6.223 1. 00 0.00 ATOM 132 C ASP 131 16. 116 1.461 3.095 1. 00 0. 00 ATOM 133 O ASP 131 16.782 1.417 2.062 1. 00 0. 00 ATOM 134 N LYS+ 132 15.627 0.369 3.675 1. oo 0. 00 ATOM 135 H LYS+ 132 15.111 0.463 4.503 1.00 0. 00 ATOM 136 CA LYS+ 132 15.855-0.961 3.120 1. 00 0. 00

ATOM 137 HA LYS+ 132 16.587-0.869 2.332 1.00 0.00 ATOM 138 CB LYS+ 132 16.400-1.897 4.205 1.00 0.00 ATOM 139 1HB LYS+ 132 15.571-2.411 4.667 1.00 0.00 ATOM 140 2HB LYS+ 132 16.903-1.301 4.954 1.00 0.00 ATOM 141 QB LYS+ 132 16.237-1.856 4.810 1.00 0.00 ATOM 142 CG LYS+ 132 17.382-2.939 3.686 1.00 0.00 ATOM 143 1HG LYS+ 132 18.129-3.121 4.444 1.00 0.00 ATOM 144 2HG LYS+ 132 17.857-2.557 2.794 1.00 0.00 ATOM 145 QG LYS+ 132 17.993-2.839 3.619 1.00 0.00 ATOM 146 CD LYS+ 132 16.679-4.249 3.352 1.00 0.00 ATOM 147 1HD LYS+ 132 15.887-4.047 2.643 1.00 0.00 ATOM 148 2HD LYS+ 132 16.256-4.661 4.256 1.00 0.00 ATOM 149 QD LYS+ 132 16.071-4.354 3.449 1.00 0.00 ATOM 150 CE LYS+ 132 17.637-5.262 2.746 1.00 0.00 ATOM 151 1HE LYS+ 132 17.985-4.884 1.794 1.00 0.00 ATOM 152 2HE LYS+ 132 17.108-6.192 2.591 1.00 0.00 ATOM 153 QE LYS+ 132 17.546-5.538 2.192 1.00 0.00 ATOM 154 NZ LYS+ 132 18.812-5.512 3.628 1.00 0.00 ATOM 155 1HZ LYS+ 132 18.888-4.761 4.345 1.00 0.00 ATOM 156 2HZ LYS+ 132 19.687-5.527 3.065 1.00 0.00 ATOM 157 3HZ LYS+ 132 18.709-6.429 4.112 1.00 0.00 ATOM 158 QZ LYS+ 132 19.094-5.572 3.841 1.00 0.00 ATOM 159 C LYS+ 132 14.568-1.538 2.537 1.00 0.00 ATOM 160 O LYS+ 132 14.597-2.459 1.718 1.00 0.00 ATOM 161 N CYS 133 13.440-1.001 2.968 1.00 0.00 ATOM 162 H CYS 133 13.478-0.276 3.622 1.00 0.00 ATOM 163 CA CYS 133 12.143-1.465 2.493 1.00 0.00 ATOM 164 HA CYS 133 12.251-2.486 2.163 1.00 0.00 ATOM 165 CB CYS 133 11.111-1.403 3.620 1.00 0.00 ATOM 166 1HB CYS 133 10.139-1.205 3.189 1.00 0.00 ATOM 167 2HB CYS 133 11.368-0.592 4.284 1.00 0.00 ATOM 168 QB CYS 133 10.753-0.899 3.736 1.00 0.00 ATOM 169 SG CYS 133 10.969-2.919 4.623 1.00 0.00 ATOM 170 C CYS 133 11.666-0.609 1.329 1.00 0.00 ATOM 171 O CYS 133 12.168 0.481 1.116 1.00 0.00 ATOM 172 N LYS+ 134 10.683-1.101 0.595 1.00 0.00 ATOM 173 H LYS+ 134 10.307-1.977 0.826 1.00 0.00 ATOM 174 CA LYS+ 134 10.122-0.373-0.533 1.00 0.00 ATOM 175 HA LYS+ 134 10.829 0.389-0.828 1.00 0.00 ATOM 176 CB LYS+ 134 9.878-1.328-1.709 1.00 0.00 ATOM 177 1HB LYS+ 134 9.233-2.128-1.374 1.00 0.00 ATOM 178 2HB LYS+ 134 10.824-1.748-2.016 1.00 0.00 ATOM 179 QB LYS+ 134 10.028-1.938-1.695 1.00 0.00 ATOM 180 CG LYS+ 134 9.233-0.673-2.923 1.00 0.00 ATOM 181 1HG LYS+ 134 9.573 0.351-2.990 1.00 0.00 ATOM 182 2HG LYS+ 134 8.160-0.690-2.804 1.00 0.00 ATOM 183 QG LYS+ 134 8.866-0.170-2.897 1.00 0.00 ATOM 184 CD LYS+ 134 9.601-1.400-4.210 1.00 0.00 ATOM 185 1HD LYS+ 134 10.244-2.235-3.970 1.00 0.00 ATOM 186 2HD LYS+ 134 10.129-0.715-4.859 1.00 0.00 ATOM 187 QD LYS+ 134 10.186-1.475-4.415 1.00 0. 00 ATOM 188 CE LYS+ 134 8.369-1.916-4.940 1.00 0.00' ATOM 189 1HE LYS+ 134 8.686-2.595-5.719 1.00 0.00 ATOM 190 2HE LYS+ 134 7.853-1.076-5.386 1.00 0.00 ATOM 191 QE LYS+ 134 8.269-1.836-5.553 1.00 0.00 ATOM 192 NZ LYS+ 134 7.432-2.629-4.025 1.00 0.00 ATOM 193 1HZ LYS+ 134 7.012-3.450-4.507 1.00 0.00 ATOM 194 2HZ LYS+ 134 6.665-1.990-3.728 1. 00 0. 00 ATOM 195 3HZ LYS+ 134 7.937-2.960-3.178 1.00 0.00 ATOM 196 QZ LYS+ 134 7.204-2.800-3.804 1.00 0.00 ATOM 197 C LYS+ 134 8.821 0.285-0.107 1.00 0.00 ATOM 198 O LYS+ 134 7.839-0.398 0.162 1.00 0.00 ATOM 199 N PHE 135 8.828 1.602-0.029 1.00 0.00 ATOM 200 H PHE 135 9.648 2.090-0.247 1.00 0.00 ATOM 201 CA PHE 135 7.651 2.350 0.390 1.00 0.00 ATOM 202 HA PHE 135 7.042 1.693 0.995 1.00 0.00 ATOM 203 CB PHE 135 8.114 3.540 1.253 1.00 0.00 ATOM 204 1HB PHE 135 9.150 3.746 1.021 1.00 0.00 ATOM 205 2HB PHE 135 8.045 3.257 2.291 1.00 0.00 ATOM 206 QB PHE 135 8.597 3.501 1.656 1.00 0.00 ATOM 207 QD PHE 135 7.274 4.973 1.086 1.00 0.00 ATOM 208 QE PHE 135 6.078 7.110 0.883 1.00 0.00

ATOM 209 QR PHE 135 6.436 6.470 0.944 1.00 0.00 ATOM 210 CG PHE 135 7.354 4.828 1.099 1.00 0.00 ATOM 211 CD1 PHE 135 7.753 5.776 0.171 1.00 0.00 ATOM 212 1HD PHE 135 8.598 5.567-0.471 1.00 0.00 ATOM 213 CE1 PHE 135 7.084 6.977 0.054 1.00 0.00 ATOM 214 1HE PHE 135 7.407 7.707-0.674 1.00 0.00 ATOM 215 CZ PHE 135 6.005 7.243 0.869 1.00 0.00 ATOM 216 HZ PHE 135 5.478 8.182 0.781 1.00 0.00 ATOM 217 CE2 PHE 135 5.597 6.306 1.798 1.00 0.00 ATOM 218 2HE PHE 135 4.749 6.514 2.441 1.00 0.00 ATOM 219 CD2 PHE 135 6.272 5.109 1.914 1.00 0.00 ATOM 220 2HD PHE 135 5.950 4.379 2.643 1.00 0.00 ATOM 221 C PHE 135 6.844 2.771-0.833 1.00 0.00 ATOM 222 O PHE 135 7.365 3.397-1.754 1.00 0.00 ATOM 223 N LEU 136 5.580 2.373-0.854 1.00 0.00 ATOM 224 H LEU 136 5.233 1.842-0.103 1.00 0.00 ATOM 225 CA LEU 136 4.700 2.667-1.973 1.00 0.00 ATOM 226 HA LEU 136 5.256 3.264-2.682 1.00 0.00 ATOM 227 CB LEU 136 4.240 1.378-2.660 1.00 0.00 ATOM 228 1HB LEU 136 3.606 1.648-3.491 1.00 0.00 ATOM 229 2HB LEU 136 3.650 0.813-1.952 1.00 0.00 ATOM 230 QB LEU 136 3.628 1.230-2.722 1.00 0.00 ATOM 231 CG LEU 136 5.356 0.475-3.183 1.00 0.0. 0 ATOM 232 HG LEU 136 6.260 1.054-3.288 1.00 0.00 ATOM 233 QD1 LEU 136 5.689-0.916-1.966 1.00 0.00 ATOM 234 QD2 LEU 136 4.901-0.217-4.871 1.00 0.00 ATOM 235 CD1 LEU 136 5.626-0.650-2.201 1.00 0.00 ATOM 236 1HD1 LEU 136 5.121-1.546-2.530 1.00 0.00 ATOM 237 2HD1 LEU 136 5.258-0.368-1.224 1.00 0.00 ATOM 238 3HD1 LEU 136 6.688-0.833-2.145 1.00 0.00 ATOM 239 CD2 LEU 136 4.989-0.085-4.548 1.00 0.00 ATOM 240 1HD2 LEU 136 4.544-1.062-4.428 1.00 0.00 ATOM 241 2HD2 LEU 136 5.877-0.164-5.156 1.00 0.00 ATOM 242 3HD2 LEU 136 4.282 0.575-5.029 1.00 0.00 ATOM 243 QQD LEU 136 5.295-0.566-3.419 1.00 0.00 ATOM 244 C LEU 136 3.481 3.450-1.518 1.00 0.00 ATOM 245 O LEU 136 2.441 2.870-1.219 1.00 0.00 ATOM 246 N HIS+ 137 3.608 4.762-1.496 1.00 0.00 ATOM 247 H HIS+ 137 4.460 5.164-1.767 1.00 0.00 ATOM 248 CA HIS+ 137 2.507 5.632-1.113 1.00 0.00 ATOM 249 HA HIS+ 137 1.830 5.070-0.477 1.00 0.00 ATOM 250 CB HIS+ 137 3.054 6.850-0.360 1.00 0.00 ATOM 251 1HB HIS+ 137 3.729 7.377-1.012 1.00 0.00 ATOM 252 2HB HIS+ 137 3.605 6.505 0.502 1.00 0.00 ATOM 253 QB HIS+ 137 3.667 6.941-0.255 1.00 0.00 ATOM 254 CG HIS+ 137 2.030 7.833 0.130 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.231 8.588-0.704 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.712 8.214 1.389 1.00 0.00 ATOM 257 1HD HIS+ 137 1.216 8.543-1.692 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.473 9.388 0.022 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.744 9.180 1.296 1.00 0.00 ATOM 260 2HD HIS+ 137 2.142 7.824 2.304 1.00 0.00 ATOM 261 1HE HIS+ 137-0.257 10.087-0.365 1.00 0.00 ATOM 262 2HE HIS+ 137 0.205 9.509 2.044 1.00 0.00 ATOM 263 C HIS+ 137 1.790 6.069-2.383 1.00 0.00 ATOM 264 O HIS+ 137 2.228 7.000-3.058 1.00 0.00 ATOM 265 N GLN 138 0.721 5.372-2.735 1.00 0.00 ATOM 266 H GLN 138 0.429 4.615-2.178 1.00 0.00 ATOM 267 CA GLN 138-0.007 5.686-3.957 1.00 0.00 ATOM 268 HA GLN 138 0.399 6.602-4.360 1.00 0.00 ATOM 269 CB GLN 138 0.178 4.561-4.985 1.00 0.00 ATOM 270 1HB GLN 138 0.135 4.989-5.976 1.00 0.00 ATOM 271 2HB GLN 138-0.630 3.853-4.874 1.00 0.00 ATOM 272 QB GLN 138-0.248 4.421-5.425 1.00 0.00 ATOM 273 CG GLN 138 1.497 3.806-4.850 1.00 0.00 ATOM 274 1HG GLN 138 1.337 2.777-5.137 1.00 0.00 ATOM 275 2HG GLN 138 1.813 3.845-3.818 1.00 0.00 ATOM 276 QG GLN 138 1.575 3.311-4.478 1.00 0.00 ATOM 277 CD GLN 138 2.603 4.383-5.714 1.00 0.00 ATOM 278 OE1 GLN 138 2.348 4.906-6.797 1.00 0.00 ATOM 279 NE2 GLN 138 3.841 4.285-5.241 1.00 0.00 ATOM 280 1HE2 GLN 138 3.974 3.851-4.374 1.00 0. 00

ATOM 281 2HE2 GLN 138 4.572 4.653-5.780 1.00 0.00 ATOM 282 QE2 GLN 138 4.273 4.252-5.077 1.00 0.00 ATOM 283 C GLN 138-1.493 5.882-3.677 1.00 0.00 ATOM 284 0 GLN 138-2.113 5.083-2.970 1.00 0.00 ATOM 285 N GLU 139-2.061 6.941-4.238 1.00 0.00 ATOM 286 H GLU 139-1.518 7.540-4.791 1.00 0.00 ATOM 287 CA GLU 139-3.475 7.236-4.050 1.00 0.00 ATOM 288 HA GLU 139-3.802 6.712-3.164 1.00 0.00 ATOM 289 CB GLU 139-3. 695 8.741-3.843 1.00 0.00 ATOM 290 1HB GLU 139-4.041 8.905-2.832 1.00 0.00 ATOM 291 2HB GLU 139-4.454 9.077-4.530 1.00 0.00 ATOM 292 QB GLU 139-4.248 8.991-3.681 1.00 0.00 ATOM 293 CG GLU 139-2.451 9.590-4.059 1.00 0.00 ATOM 294 1HG GLU 139-2.755 10.584-4.351 1.00 0.00 ATOM 295 2HG GLU 139-1.859 9.150-4.846 1.00 0.00 ATOM 296 QG GLU 139-2.307 9.867-4.599 1.00 0.00 ATOM 297 CD GLU 139-1. 600 9.692-2.814 1.00 0.00 ATOM 298 OE1 GLU 139-0.380 9.456-2.916 1.00 0.00 ATOM 299 OE2 GLU 139-2. 154 9.997-1.737 1.00 0.00 ATOM 300 C GLU 139-4.303 6.749-5.239 1.00 0.00 ATOM 301 O GLU 139-4.292 7.356-6.310 1.00 0.00 ATOM 302 N ARG+ 140-5.032 5.661-5.035 1.00 0.00 ATOM 303 H ARG+ 140-5.012 5.232-4.153 1.00 0.00 ATOM 304 CA ARG+ 140-5.886 5.097-6.074 1.00 0.00 ATOM 305 HA ARG+ 140-5.513 5.422-7.034 1.00 0.00 ATOM 306 CB ARG+ 140-5.856 3.562-6.004 1.00 0.00 ATOM 307 1HB ARG+ 140-6.431 3.245-5.144 1.00 0.00 ATOM 308 2HB ARG+ 140-4.835 3.239-5.880 1.00 0.00 ATOM 309 QB ARG+ 140-5.633 3.242-5.512 1.00 0.00 ATOM 310 CG ARG+ 140-6.428 2.873-7.232 1.00 0.00 ATOM 311 1HG ARG+ 140-7.269 3.450-7.595 1.00 0.00 ATOM 312 2HG ARG+ 140-6. 762 1.885-6.953 1.00 0.00 ATOM 313 QG ARG+ 140-7.016 2.667-7.274 1.00 0.00 ATOM 314 CD ARG+ 140-5.398 2.751-8.342 1.00 0.00 ATOM 315 1HD ARG+ 140-4.412 2.860-7.915 1.00 0.00 ATOM 316 2HD ARG+ 140-5.568 3.543-9.060 1.00 0.00 ATOM 317 QD ARG+ 140-4.990 3.201-8.488 1.00 0.00 ATOM 318 NE ARG+ 140-5.483 1.460-9.029 1.00 0.00 ATOM 319 HE ARG+ 140-4.927 0.728-8.683 1.00 0.00 ATOM 320 CZ ARG+ 140-6.266 1.234-10.086 1.00 0.00 ATOM 321 NH1 ARG+ 140-7.040 2.203-10.562 1.00 0.00 ATOM 322 1HH1 ARG+ 140-7.042 3.117-10.120 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.626 2.042-11.354 1.00 0.00 ATOM 324 QH1 ARG+ 140-7.334 2.579-10.737 1.00 0.00 ATOM 325 NH2 ARG+ 140-6. 279 0.036-10.661 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.703-0.700-10.302 1.00 0. 00 ATOM 327 2HH2 ARG+ 140-6.866-0.135-11.454 1.00 0.00 ATOM 328 QH2 ARG+ 140-6.285-0.418-10.878 1.00 0.00 ATOM 329 C ARG+ 140-7. 312 5.604-5.889 1.00 0.00 ATOM 330 O ARG+ 140-8.158 4.907-5.331 1.00 0.00 ATOM 331 N MET 141-7.570 6.829-6.342 1.00 0.00 ATOM 332 H MET 141-6.848 7.339-6.767 1.00 0.00 ATOM 333 CA MET 141-8.893 7.447-6.203 1.00 0.00 ATOM 334 HA MET 141-9. 228 7.280-5.192 1.00 0.00 ATOM 335 CB MET 141-8.785 8.958-6.448 1.00 0.00 ATOM 336 1HB MET 141-8.969 9.149-7.496 1.00 0.00 ATOM 337 2HB MET 141-7.784 9.280-6.203 1.00 0.00 ATOM 338 QB MET 141-8.377 9.214-6.850 1.00 0.00 ATOM 339 CG MET 141-9. 768 9.792-5.635 1.00 0.00 ATOM 340 1HG MET 141-9.215 10.554-5.104 1.00 0.00 ATOM 341 2HG MET 141-10.259 9.147-4.922 1.00 0. 00 ATOM 342 QG MET 141-9.737 9.850-5.013 1.00 0. 00 ATOM 343 SD MET 141-11. 030 10.593-6.646 1.00 0.00 ATOM 344 QE MET 141-9.858 11.285-8.314 1.00 0.00 ATOM 345 CE MET 141-10.053 11.170-8.034 1.00 0. 00 ATOM 346 1HE MET 141-9. 043 11.367-7.707 1.00 0. 00 ATOM 347 2HE MET 141-10. 488 12.077-8.429 1. oo o. oo ATOM 348 3HE MET 141-10.041 10.412-8.805 1.00 0. 00 ATOM 349 C MET 141-9.915 6.831-7. 165 1. 00 0. 00 ATOM 350 O MET 141-10.825 7.512-7. 639 1. 00 0. 00 ATOM 351 N ASP 142-9.761 5. 5A4-7 : 441 1.00 0. 00 ATOM 352 H ASP 142-9.023 5.057-7.028 1.00 0.00

ATOM 353 CA ASP 142-10.651 4.832-8.337 1.00 0.00 ATOM 354 HA ASP 142-11.342 5.545-8.761 1.00 0.00 ATOM 355 CB ASP 142-9.851 4.177-9.463 1.00 0.00 ATOM 356 1HB ASP 142-10.500 4.031-10.303 1.00 0.00 ATOM 357 2HB ASP 142-9.488 3.219-9.126 1.00 0.00 ATOM 358 QB ASP 142-9.994 3.625-9.715 1.00 0.00 ATOM 359 CG ASP 142-8.666 5.004-9.913 1.00 0.00 ATOM 360 OD1 ASP 142-8.877 6.021-10.596 1.00 0.00 ATOM 361 OD2 ASP 142-7.522 4.622-9.591 1.00 0.00 ATOM 362 C ASP 142-11.431 3.759-7.592 1.00 0.00 ATOM 363 O ASP 142-12.632 3.590-7.798 1.00 0.00 ATOM 364 N VAL 143-10.734 3.018-6.742 1.00 0.00 ATOM 365 H VAL 143-9.776 3.189-6.630 1.00 0.00 ATOM 366 CA VAL 143-11.358 1.942-5.987 1.00 0.00 ATOM 367 HA VAL 143-12.314 1.733-6.445 1.00 0.00 ATOM 368 CB VAL 143-10.504 0.657-6.039 1.00 0.00 ATOM 369 HB VAL 143-9.863 0.641-5.169 1.00 0.00 ATOM 370 QG1 VAL 143-11.597-0.871-5.986 1.00 0.00 ATOM 371 QG2 VAL 143-9.413 0.630-7.572 1.00 0.00 ATOM 372 CG1 VAL 143-11.388-0.577-5.997 1.00 0.00 ATOM 373 1HG1 VAL 143-11.279-1.066-5.038 1.00 0.00 ATOM 374 2HG1 VAL 143-11.091-1.257-6.782 1.00 0.00 ATOM 375 3HG1 VAL 143-12.419-0.290-6.139 1.00 0.00 ATOM 376 CG2 VAL 143-9.621 0.635-7.280 1.00 0.00 ATOM 377 1HG2 VAL 143-9. 690-0.333-7.752 1.00 0.00 ATOM 378 2HG2 VAL 143-8.597 0.826-6.995 1.00 0.00 ATOM 379 3HG2 VAL 143-9.951 1.398-7.970 1.00 0.00 ATOM 380 QQG VAL 143-10.505-0.120-6.779 1.00 0.00 ATOM 381 C VAL 143-11.591 2.363-4.534 1.00 0.00 ATOM 382 0 VAL 143-10.880 3.215-4.007 1.00 0.00 ATOM 383 N CYS 144-12. 600 1.776-3.895 1.00 0.00 ATOM 384 H CYS 144-13.140 1.109-4.366 1.00 0.00 ATOM 385 CA CYS 144-12.932 2.113-2.512 1.00 0.00 ATOM 386 HA CYS 144-12.084 2.625-2.078 1.00 0.00 ATOM 387 CB CYS 144-14.146 3.044-2.481 1.00 0.00 ATOM 388 1HB CYS 144-14.333 3.345-1.462 1.00 0.00 ATOM 389 2HB CYS 144-15.007 2.508-2.854 1.00 0.00 ATOM 390 QB CYS 144-14.670 2.926-2.158 1.00 0.00 ATOM 391 SG CYS 144-13.960 4.555-3.485 1.00 0.00 ATOM 392 C CYS 144-13.229 0.864-1.691 1.00 0.00 ATOM 393 0 CYS 144-14.357 0.369-1.689 1.00 0.00 ATOM 394 N GLU 145-12.220 0.360-0.992 1.00 0.00 ATOM 395 H GLU 145-11.342 0.796-1.031 1.00 0.00 ATOM 396 CA GLU 145-12.383-0.835-0.178 1.00 0.00 ATOM 397 HA GLU 145-13.423-1.113-0.210 1.00 0. 00 ATOM 398 CB GLU 145-11.561-1.967-0.781 1.00 0.00 ATOM 399 1HB GLU 145-11.253-2.640 0.002 1.00 0.00 ATOM 400 2HB GLU 145-10.679-1.548-1.251 1.00 0. 00 ATOM 401 QB GLU 145-10.966-2.094-0.625 1.00 0.00 ATOM 402 CG GLU 145-12.336-2.763-1.822 1.00 0.00 ATOM 403 1HG GLU 145-13.087-2.121-2.259 1.00 0.00 ATOM 404 2HG GLU 145-12.818-3.596-1.334 1.00 0.00 ATOM 405 QG GLU 145-12.953-2.859-1.797 1.00 0.00 ATOM 406 CD GLU 145-11.459-3.300-2.930 1.00 0.00 ATOM 407 OE1 GLU 145-10.429-3.930-2.618 1.00 0. 00 ATOM 408 OE2 GLU 145-11.810-3.101-4.108 1.00 0.00 ATOM 409 C GLU 145-11.987-0.589 1.277 1.00 0.00 ATOM 410 O GLU 145-11.636 0.529 1.656 1.00 0.00 ATOM 411 N THR 146-12.062-1.643 2.084 1.00 0.00 ATOM 412 H THR 146-12.356-2.500 1.714 1.00 0.00 ATOM 413 CA THR 146-11.730-1.567 3.504 1.00 0.00 ATOM 414 HA THR 146-11.999-0.580 3.854 1.00 0.00 ATOM 415 CB THR 146-12.559-2.615 4.266 1.00 0. 00 ATOM 416 HB THR 146-12.263-3.600 3.934 1.00 0.00 ATOM 417 QG2 THR 146-12.374-2.557 6.133 1.00 0.00 ATOM 418 OG1 THR 146-13.937-2.447 3.982 1.00 0.00 ATOM 419 1HG THR 146-14.326-1.833 4.636 1.00 0.00 ATOM 420 CG2 THR 146-12.408-2.569 5.773 1.00 0.00 ATOM 421 1HG2 THR 146-11.360-2.573 6.032 1.00 0.00 ATOM 422 2HG2 THR 146-12.891-3.431 6.211 1.00 0. 00 ATOM 423 3HG2 THR 146-12. 870-1.666 6.155 1.00 0.00 ATOM 424 C THR 146-10.226-1.777 3.718 1.00 0.00

ATOM 425 O THR 146-9.515-2.201 2.806 1.00 0.00 ATOM 426 N HIS+ 147-9.754-1.467 4.927 1.00 0.00 ATOM 427 H HIS+ 147-10.383-1.126 5.600 1.00 0.00 ATOM 428 CA HIS+ 147-8.340-1.599 5.291 1.00 0.00 ATOM 429 HA HIS+ 147-7. 787-0.868 4.721 1.00 0.00 ATOM 430 CB HIS+ 147-8.157-1.298 6.781 1.00 0.00 ATOM 431 1HB HIS+ 147-8.072-2.231 7.320 1.00 0.00 ATOM 432 2HB HIS+ 147-9.021-0.759 7.142 1.00 0.00 ATOM 433 QB HIS+ 147-8.547-1.495 7.231 1.00 0.00 ATOM 434 CG HIS+ 147-6.943-0.476 7.090 1.00 0.00 ATOM 435 ND1 HIS+ 147-6.973 0.897 7.216 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.659-0.845 7.318 1.00 0.00 ATOM 437 1HD HIS+ 147-7.766 1.469 7.100 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.761 1.337 7.510 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.944 0.300 7.580 1.00 0.00 ATOM 440 2HD HIS+ 147-5. 266-1.853 7.287 1.00 0.00 ATOM 441 1HE HIS+ 147-5.485 2.370 7.671 1.00 0.00 ATOM 442 2HE HIS+ 147-4.027 0.328 7. 932 1.00 0.00 ATOM 443 C HIS+ 147-7.777-2.986 4.979 1.00 0.00 ATOM 444 0 HIS+ 147-6.622-3.110 4.583 1.00 0.00 ATOM 445 N LEU 148-8.587-4.024 5.165 1.00 0.00 ATOM 446 H LEU 148-9.498-3.868 5.485 1.00 0.00 ATOM 447 CA LEU 148-8.147-5.392 4.905 1.00 0.00 ATOM 448 HA LEU 148-7.201-5.535 5.406 1.00 0.00 ATOM 449 CB LEU 148-9.165-6.388 5.472 1.00 0.00 ATOM 450 1HB LEU 148-10.149-6.090 5.145 1.00 0.00 ATOM 451 2HB LEU 148-9.129-6.332 6.550 1.00 0.00 ATOM 452 QB LEU 148-9. 639-6.211 5.847 1.00 0.00 ATOM 453 CG LEU 148-8.947-7.845 5.060 1.00 0.00 ATOM 454 HG LEU 148-8.619-7.872 4.032 1.00 0.00 ATOM 455 QD1 LEU 148-7.611-8.643 6.115 1.00 0.00 ATOM 456 QD2 LEU 148-10.551-8.817 5.189 1.00 0.00 ATOM 457 CD1 LEU 148-7.867-8.489 5.914 1.00 0.00 ATOM 458 INDI LEU 148-6.925-8.459 5.386 1.00 0.00 ATOM 459 2HD1 LEU 148-8.133-9.517 6.114 1.00 0.00 ATOM 460 3HD1 LEU 148-7.775-7.953 6.846 1.00 0.00 ATOM 461 CD2 LEU 148-10.244-8.630 5.164 1.00 0.00 ATOM 462 1HD2 LEU 148-10.030-9.687 5.090 1.00 0.00 ATOM 463 2HD2 LEU 148-10.906-8.341 4.362 1.00 0.00 ATOM 464 3HD2 LEU 148-10.715-8.424 6.114 1.00 0.00 ATOM 465 QQD LEU 148-9.081-8.730 5.652 1.00 0.00 ATOM 466 C LEU 148-7.951-5.630 3.414 1.00 0.00 ATOM 467 O LEU 148-7.020-6.321 3.004 1.00 0.00 ATOM 468 N HIS+ 149-8.830-5.052 2.608 1.00 0.00 ATOM 469 H HIS+ 149-9.546-4.508 2.995 1.00 0.00 ATOM 470 CA HIS+ 149-8.755-5.201 1.162 1.00 0.00 ATOM 471 HA HIS+ 149-8.708-6.260 0.948 1.00 0.00 ATOM 472 CB HIS+ 149-10.008-4.627 0.509 1.00 0.00 ATOM 473 1HB HIS+ 149-9.750-4.190-0.448 1.00 0.00 ATOM 474 2HB HIS+ 149-10.422-3.860 1.147 1.00 0.00 ATOM 475 QB HIS+ 149-10.086-4.025 0.349 1.00 0.00 ATOM 476 CG HIS+ 149-11.069-5.658 0.274 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.548-6.490 1.265 1.00 0.00 ATOM 478 CD2 HIS+ 149-11.736-5.996-0.852 1.00 0.00 ATOM 479 1HD HIS+ 149-11.252-6.499 2.199 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.465-7.295 0.754 1.00 0.00 ATOM 481 NE2 HIS+ 149-12.597-7.014-0.532 1.00 0.00 ATOM 482 2HD HIS+ 149-11.613-5.540-1.829 1.00 0.00 ATOM 483 1HE HIS+ 149-13.014-8.053 1.294 1.00 0.00 ATOM 484 2HE HIS+ 149-13.069-7.575-1.184 1.00 0.00 ATOM 485 C HIS+ 149-7.492-4.549 0.613 1.00 0.00 ATOM 486 O HIS+ 149-6.700-5.205-0.054 1.00 0.00 ATOM 487 N TRP 150-7. 291-3.269 0.921 1.00 0.00 ATOM 488 H TRP 150-7.951-2.799 1.474 1.00 0.00 ATOM 489 CA TRP 150-6. 093-2.554 0.469 1.00 0.00 ATOM 490 HA TRP 150-6.058-2.597-0.611 1.00 0.00 ATOM 491 CB TRP 150-6.120-1.096 0.924 1.00 0.00 ATOM 492 1HB TRP 150-5.137-0.669 0.777 1. 00 0.00 ATOM 493 2HB TRP 150-6.360-1.063 1.976 1.00 0.00 ATOM 494 QB TRP 150-5.749-0.866 1.376 1.00 0.00 ATOM 495 CG TRP 150-7. 109-0.232 0.205 1.00 0.00 ATOM 496 CD1 TRP 150-7. 563 0.986 0.614 1.00 0.00

ATOM 497 CD2 TRP 150-7. 761-0.504-1.040 1.00 0.00 ATOM 498 CE3 TRP 150-7. 723-1.565-1. 947 1.00 0.00 ATOM 499 CE2 TRP 150-8.593 0.593-1.319 1.00 0.00 ATOM 500 NE1 TRP 150-8. 457 1.486-0.296 1.00 0.00 ATOM 501 HD TRP 150-7. 255 1.474 1.526 1.00 0.00 ATOM 502 3HE TRP 150-7.099-2.428-1.773 1.00 0.00 ATOM 503 CZ3 TRP 150-8.503-1.499-3. 078 1.00 0.00 ATOM 504 CZ2 TRP 150-9. 377 0.658-2.462 1.00 0.00 ATOM 505 1HE TRP 150-8. 922 2.344-0.224 1.00 0.00 ATOM 506 3HZ TRP 150-8. 496-2. 315-3.785 1.00 0.00 ATOM 507 CH2 TRP 150-9.319-0.395-3.326 1.00 0.00 ATOM 508 2HZ TRP 150-10.014 1.505-2.674 1.00 0.00 ATOM 509 HH TRP 150-9. 916-0.391-4.226 1.00 0.00 ATOM 510 C TRP 150-4.843-3.220 1.002 1.00 0.00 ATOM 511 O TRP 150-3. 817-3.238 0.332 1.00 0.00 ATOM 512 N HIS+ 151-4.936-3.788 2.199 1.00 0.00 ATOM 513 H HIS+ 151-5.788-3.757 2.682 1.00 0.00 ATOM 514 CA HIS+ 151-3.804-4.480 2.785 1.00 0.00 ATOM 515 HA HIS+ 151-2.974-3.791 2.821 1.00 0.00 ATOM 516 CB HIS+ 151-4.130-4.968 4.207 1.00 0. 00 ATOM 517 1HB HIS+ 151-4. 934-5.690 4.153 1.00 0.00 ATOM 518 2HB HIS+ 151-4.451-4.126 4.802 1.00 0.00 ATOM 519 QB HIS+ 151-4.693-4.908 4.477 1.00 0.00 ATOM 520 CG HIS+ 151-2.973-5.618 4.913 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.984-5.929 6.257 1.00 0.00 ATOM 522 CD2 HIS+ 151-1.767-6.024 4.450 1.00 0.00 ATOM 523 1HD HIS+ 151-3.724-5.759 6. 881 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.834-6.494 6.585 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.078-6.563 5.507 1.00 0.00 ATOM 526 2HD HIS+ 151-1.424-5.953 3.422 1.00 0.00 ATOM 527 1HE HIS+ 151-1.558-6.837 7.572 1.00 0.00 ATOM 528 2HE HIS+ 151-0.123-6.786 5.505 1.00 0.00 ATOM 529 C HIS+ 151-3.436-5.656 1.895 1.00 0.00 ATOM 530 O HIS+ 151-2. 272-5.845 1.561 1.00 0.00 ATOM 531 N THR 152-4.441-6.428 1.507 1.00 0.00 ATOM 532 H THR 152-5.351-6.214 1.802 1.00 0.00 ATOM 533 CA THR 152-4.230-7.578 0.646 1.00 0.00 ATOM 534 HA THR 152-3.490-8.208 1.115 1.00 0.00 ATOM 535 CB THR 152-5.532-8.370 0.491 1.00 0.00 ATOM 536 HB THR 152-6.211-7.807-0.135 1.00 0.00 ATOM 537 QG2 THR 152-5.295-10.056-0.294 1.00 0.00 ATOM 538 OG1 THR 152-6.146-8.572 1.755 1.00 0.00 ATOM 539 1HG THR 152-6. 516-7.740 2.072 1.00 0.00 ATOM 540 CG2 THR 152-5.340-9.732-0.142 1.00 0.00 ATOM 541 1HG2 THR 152-4.824-9.622-1.087 1.00 0.00 ATOM 542 2HG2 THR 152-6.304-10.189-0.311 1.00 0.00 ATOM 543 3HG2 THR 152-4.755-10.357 0.516 1.00 0.00 ATOM 544 C THR 152-3.700-7.148-0.717 1.00 0.00 ATOM 545 O THR 152-2.738-7.727-1.199 1.00 0.00 ATOM 546 N VAL 153-4.311-6.122-1.314 1.00 0.00 ATOM 547 H VAL 153-5.064-5.684-0.859 1.00 0.00 ATOM 548 CA VAL 153-3.871-5.622-2.620 1.00 0.00 ATOM 549 HA VAL 153-3.939-6.436-3.325 1.00 0. 00 ATOM 550 CB VAL 153-4.762-4.461-3.120 1.00 0.00 ATOM 551 HB VAL 153-4.653-3.628-2.440 1.00 0.00 ATOM 552 QG1 VAL 153-4.233-3.89,7-4.835 1.00 0.00 ATOM 553 QG2 VAL 153-6.569-4.979-3.136 1.00 0.00 ATOM 554 CG1 VAL 153-4.334-4.004-4.507 1.00 0.00 ATOM 555 1HG1 VAL 153-4. 356-4.846-5.185 1.00 0.00 ATOM 556 2HG1 VAL 153-3. 331-3.605-4.462 1.00 0.00 ATOM 557 3HG1 VAL 153-5.011-3.241-4.859 1.00 0.00 ATOM 558 CG2 VAL 153-6.223-4.879-3.133 1.00 0.00 ATOM 559 1HG2 VAL 153-6.809-4.129-3.643 1.00 0.00 ATOM 560 2HG2 VAL 153-6.577-4.984-2.118 1.00 0.00 ATOM 561 3HG2 VAL 153-6.321-5.824-3.648 1.00 0.00 ATOM 562 QQG VAL 153-5.401-4.438-3.986 1.00 0.00 ATOM 563 C VAL 153-2.425-5.166-2.551 1.00 0.00 ATOM 564 O VAL 153-1.583-5.586-3.341 1.00 0.00 ATOM 565 N ALA 154-2.145-4.316-1.586 1.00 0.00 ATOM 566 H ALA 154-2.869-4.025-0.982 1.00 0.00 ATOM 567 CA ALA 154-0. 801-3.810-1.381 1.00 0.00 ATOM 568 HA ALA 154-0.496-3.275-2.268 1.00 0.00

ATOM 569 QB ALA 154-0. 800-2.622 0. 069 1.00 0.00 ATOM 570 CB ALA 154-0. 800-2.851-0.209 1.00 0.00 ATOM 571 1HB ALA 154-1. 815-2.550 0.011 1.00 0.00 ATOM 572 2HB ALA 154-0.211-1.979-0.459 1.00 0.00 ATOM 573 3HB ALA 154-0.374-3.337 0.656 1.00 0.00 ATOM 574 C ALA 154 0.177-4.952-1.122 1.00 0.00 ATOM 575 O ALA 154 1.268-5. 003-1.696 1.00 0.00 ATOM 576 N LYS+ 155-0.227-5.865-0.249 1.00 0.00 ATOM 577 H LYS+ 155-1.110-5.763 0.172 1.00 0.00 ATOM 578 CA LYS+ 155 0.595-7.010 0.107 1.00 0.00 ATOM 579 HA LYS+ 155 1.553-6.637 0.453 1.00 0.00 ATOM 580 CB LYS+ 155-0.069-7.810 1.235 1.00 0.00 ATOM 581 1HB LYS+ 155-1. 074-8. 068 0.928 1.00 0.00 ATOM 582 2HB LYS+ 155-0. 125-7.188 2.116 1.00 0.00 ATOM 583 QB LYS+ 155-0.600-7.628 1.522 1.00 0.00 ATOM 584 CG LYS+ 155 0.658-9.095 1.606 1.00 0.00 ATOM 585 1HG LYS+ 155 1.042-9.003 2.612 1.00 0.00 ATOM 586 2HG LYS+ 155 1.476-9.248 0.917 1.00 0.00 ATOM 587 QG LYS+ 155 1.259-9.126 1.764 1.00 0.00 ATOM 588 CD LYS+ 155-0.276-10.295 1.540 1.00 0.00 ATOM 589 1HD LYS+ 155-1. 052-10.093 0.814 1.00 0.00 ATOM 590 2HD LYS+ 155-0.723-10.445 2.512 1.00 0.00 ATOM 591 QD LYS+ 155-0.888-10.269 1. 663 1.00 0.00 ATOM 592 CE LYS+ 155 0.466-11.560 1.132 1.00 0.00 ATOM 593 1HE LYS+ 155 1.517-11.326 1.017 1.00 0.00 ATOM 594 2HE LYS+ 155 0.071-11.905 0.186 1.00 0.00 ATOM 595 QE LYS+ 155 0.794-11.616 0.601 1.00 0.00 ATOM 596 NZ LYS+ 155 0.318-12.646 2.145 1.00 0.00 ATOM 597 1HZ LYS+ 155 1.058-13.366 2.008 1.00 0.00 ATOM 598 2HZ LYS+ 155-0.614-13.102 2.048 1.00 0.00 ATOM 599 3HZ LYS+ 155 0.402-12.257 3.107 1.00 0.00 ATOM 600 QZ LYS+ 155 0.282-12.908 2.388 1.00 0.00 ATOM 601 C LYS+ 155 0.834-7.905-1.096 1.00 0.00 ATOM 602 O LYS+ 155 1.978-8.226-1.384 1.00 0.00 ATOM 603 N GLU 156-0.231-8.313-1.787 1.00 0.00 ATOM 604 H GLU 156-1.133-8.027-1.506 1.00 0.00 ATOM 605 CA GLU 156-0.088-9.184-2.949 1.00 0.00 ATOM 606 HA GLU 156 0.415-10.078-2.608 1.00 0.00 ATOM 607 CB GLU 156-1.451-9.591-3.534 1.00 0.00 ATOM 608 1HB GLU 156-2. 060-10.001-2.740 1.00 0.00 ATOM 609 2HB GLU 156-1.293-10.358-4.278 1.00 0.00 ATOM 610 QB GLU 156-1. 677-10.180-3.509 1.00 0.00 ATOM 611 CG GLU 156-2.233-8.465-4.188 1.00 0.00 ATOM 612 1HG GLU 156-1.955-8.408-5.230 1.00 0.00 ATOM 613 2HG GLU 156-1.987-7.534-3.697 1.00 0.00 ATOM 614 QG GLU 156-1.971-7.971-4.464 1.00 0.00 ATOM 615 CD GLU 156-3.731-8.675-4.099 1.00 0.00 ATOM 616 OE1 GLU 156-4.163-9.562-3.332 1.00 0.00 ATOM 617 OE2 GLU 156-4.473-7.944-4.786 1.00 0.00 ATOM 618 C GLU 156 0.796-8.535-4.008 1.00 0.00 ATOM 619 O GLU 156 1.633-9.201-4.598 1.00 0.00 ATOM 620 N THR 157 0.635-7.229-4.221 1.00 0.00 ATOM 621 H THR 157-0.042-6.736-3.702 1.00 0.00 ATOM 622 CA THR 157 1.459-6.514-5.194 1.00 0.00 ATOM 623 HA THR 157 1.277-6.953-6.164 1.00 0.00 ATOM 624 CB THR 157 1.074-5.028-5.229 1.00 0.00 ATOM 625 HB THR 157 1.218-4.608-4.243 1.00 0.00 ATOM 626 QG2 THR 157 2.085-4.011-6.437 1.00 0.00 ATOM 627 OG1 THR 157-0.288-4.870-5.586 1.00 0.00 ATOM 628 1HG THR 157-0.851-5.297-4.922 1.00 0.00 ATOM 629 CG2 THR 157 1.891-4.206-6.205 1.00 0.00 ATOM 630 1HG2 THR 157 1.276-3.937-7.051 1.00 0.00 ATOM 631 2HG2 THR 157 2.736-4.787-6.545 1.00 0.00 ATOM 632 3HG2 THR 157 2.244-3.310-5.716 1.00 0. 00 ATOM 633 C THR 157 2.946-6.675-4.856 1.00 0.00 ATOM 634 O THR 157 3.788-6.833-5.741 1.00 0.00 ATOM 635 N CYS 158 3.264-6.641-3.569 1.00 0. 00 ATOM 636 H CYS 158 2.551-6.510-2.900 1.00 0. 00 ATOM 637 CA CYS 158 4.646-6.794-3.126 1.00 0.00 ATOM 638 HA CYS 158 5.280-6.311-3.855 1.00 0.00 ATOM 639 CB CYS 158 4.837-6.102-1.774 1.00 0.00 ATOM 640 1HB CYS 158 5.690-6.523-1.274 1.00 0. 00

ATOM 641 2HB CYS 158 3.960-6.270-1.170 1.00 0.00 ATOM 642 QB CYS 158 4.825-6.397-1.222 1.00 0.00 ATOM 643 SG CYS 158 5.089-4.292-1.904 1.00 0.00 ATOM 644 C CYS 158 5.050-8.273-3.045 1.00 0.00 ATOM 645 O CYS 158 6.153-8.636-3.458 1.00 0.00 ATOM 646 N SER 159 4.165-9.114-2.506 1.00 0.00 ATOM 647 H SER 159 3.310-8.760-2.185 1.00 0.00 ATOM 648 CA SER 159 4.436-10.549-2.362 1.00 0.00 ATOM 649 HA SER 159 5. 389-10. 648-1.863 1.00 0.00 ATOM 650 CB SER 159 3.366-11.229-1.505 1.00 0.00 ATOM 651 1HB SER 159 3.754-12.169-1.140 1.00 0.00 ATOM 652 2HB SER 159 2.490-11.414-2.110 1.00 0.00 ATOM 653 QB SER 159 3.122-11.792-1.625 1.00 0.00 ATOM 654 OG SER 159 2.997-10.421-0.396 1.00 0.00 ATOM 655 HG SER 159 2.692-9.563-0.719 1.00 0.00 ATOM 656 C SER 159 4.527-11.264-3.710 1.00 0.00 ATOM 657 O SER 159 5.265-12.239-3.830 1.00 0.00 ATOM 658 N GLU 160 3.783-10.787-4.714 1.00 0.00 ATOM 659 H GLU 160 3.206-10.005-4.561 1.00 0.00 ATOM 660 CA GLU 160 3.809-11.400-6.043 1.00 0.00 ATOM 661 HA GLU 160 3.543-12.442-5.934 1.00 0.00 ATOM 662 CB GLU 160 2.806-10.718-6.977 1.00 0.00 ATOM 663 1HB GLU 160 3.297-9.898-7.480 1.00 0.00 ATOM 664 2HB GLU 160 1.988-10.330-6.387 1.00 0.00 ATOM 665 QB GLU 160 2.642-10.114-6.934 1.00 0.00 ATOM 666 CG GLU 160 2.228-11.647-8.033 1.00 0.00 ATOM 667 1HG GLU 160 2.994-12. 348-8.333 1.00 0.00 ATOM 668 2HG GLU 160 1.925-11.061-8.886 1.00 0.00 ATOM 669 QG GLU 160 2.459-11.705-8.610 1.00 0.00 ATOM 670 CD GLU 160 1.028-12.428-7.535 1.00 0.00 ATOM 671 OE1 GLU 160 0.972-12.727-6.323 1.00 0.00 ATOM 672 OE2 GLU 160 0.145-12.742-8.358 1.00 0.00 ATOM 673 C GLU 160 5.218-11.306-6.615 1.00 0.00 ATOM 674 O GLU 160 5.645-12.129-7.427 1.00 0.00 ATOM 675 N LYS+ 161 5.947-10.311-6.139 1.00 0.00 ATOM 676 H LYS+ 161 5.552-9.718-5.469 1.00 0.00 ATOM 677 CA LYS+ 161 7.321-10.106-6.532 1.00 0.00 ATOM 678 HA LYS+ 161 7.482-10.615-7.472 1.00 0.00 ATOM 679 CB LYS+ 161 7.631-8.610-6.688 1.00 0.00 ATOM 680 1HB LYS+ 161 7.989-8.231-5.743 1.00 0.00 ATOM 681 2HB LYS+ 161 6.720-8.094-6.947 1.00 0.00 ATOM 682 QB LYS+ 161 7.354-8.163-6.345 1.00 0.00 ATOM 683 CG LYS+ 161 8.678-8.309-7.755 1.00 0.00 ATOM 684 1HG LYS+ 161 8.211-7.745-8.552 1.00 0.00 ATOM 685 2HG LYS+ 161 9.053-9.242-8.148 1.00 0.00 ATOM 686 QG LYS+ 161 8.632-8.494-8.350 1.00 0.00 ATOM 687 CD LYS+ 161 9.846-7.504-7.200 1.00 0.00 ATOM 688 1HD LYS+ 161 10.001-7.776-6.167 1.00 0.00 ATOM 689 2HD LYS+ 161 9.609-6.451-7.266 1.00 0. 00 ATOM 690 QD LYS+ 161 9.805-7.114-6.717 1.00 0.00 ATOM 691 CE LYS+ 161 11.125-7.771-7.983 1.00 0.00 ATOM 692 1HE LYS+ 161 11.523-6.827-8.328 1.00 0.00 ATOM 693 2HE LYS+ 161 10.885-8.390-8.836 1.00 0.00 ATOM 694 QE LYS+ 161 11.204-7.609-8.582 1.00 0.00 ATOM 695 NZ LYS+ 161 12.157-8.463-7.159 1.00 0.00 ATOM 696 1HZ LYS+ 161 11.778-9.367-6.780 1.00 0.00 ATOM 697 2HZ LYS+ 161 12.447-7.864-6.361 1.00 0.00 ATOM 698 3HZ LYS+ 161 12.995-8.675-7.738 1.00 0.00 ATOM 699 QZ LYS+ 161 12.406-8.635-6.960 1.00 0.00 ATOM 700 C LYS+ 161 8.208-10.730-5.464 1.00 0.00 ATOM 701 O LYS+ 161 7.932-11.820-4.976 1.00 0.00 ATOM 702 N SER 162 9.261-10.038-5.087 1.00 0.00 ATOM 703 H SER 162 9.436-9.171-5.492 1.00 0.00 ATOM 704 CA SER 162 10.150-10.542-4.064 1.00 0.00 ATOM 705 HA SER 162 9.764-11.495-3.739 1.00 0.00 ATOM 706 CB SER 162 11.557-10.745-4.626 1.00 0.00 ATOM 707 1HB SER 162 11.964-11.671-4.241 1.00 0.00 ATOM 708 2HB SER 162 12.187-9.924-4.315 1.00 0. 00 ATOM 709 QB SER 162 12.075-10.798-4.278 1.00 0.00 ATOM 710 OG SER 162 11.535-10.806-6.049 1.00 0.00 ATOM 711 HG SER 162 11.369-11.719-6.319 1.00 0.00 ATOM 712 C SER 162 10.187-9.598-2.867 1.00 0.00

ATOM 713 O SER 162 11.257-9.195-2.428 1.00 0.00 ATOM 714 N THR 163 9.018-9.232-2.339 1.00 0.00 ATOM 715 H THR 163 8.177-9.569-2.728 1.00 0.00 ATOM 716 CA THR 163 8.965-8.344-1.182 1.00 0.00 ATOM 717 HA THR 163 9.883-8.481-0.624 1.00 0.00 ATOM 718 CB THR 163 8.862-6.874-1.593 1.00 0.00 ATOM 719 HB THR 163 8.728-6.288-0.689 1.00 0.00 ATOM 720 QG2 THR 163 10.371-6.210-2.483 1.00 0.00 ATOM 721 OG1 THR 163 7.752-6.661-2.443 1.00 0.00 ATOM 722 1HG THR 163 7.446-7.511-2.793 1.00 0.00 ATOM 723 CG2 THR 163 10. 080-6. 337-2.313 1.00 0.00 ATOM 724 1HG2 THR 163 10.768-7.148-2.509 1.00 0.00 ATOM 725 2HG2 THR 163 10.566-5.596-1.694 1.00 0.00 ATOM 726 3HG2 THR 163 9.780-5.887-3.246 1.00 0.00 ATOM 727 C THR 163 7.796-8.700-0.270 1.00 0.00 ATOM 728 O THR 163 6.847-9.364-0.679 1.00 0.00 ATOM 729 N ASN 164 7.876-8.249 0.971 1.00 0.00 ATOM 730 H ASN 164 8.667-7.725 1.235 1.00 0.00 ATOM 731 CA ASN 164 6.832-8.513 1.964 1.00 0.00 ATOM 732 HA ASN 164 5.979-8.942 1.448 1.00 0.00 ATOM 733 CB ASN 164 7.344-9.505 3.015 1.00 0.00 ATOM 734 1HB ASN 164 7.082-10.508 2.713 1.00 0.00 ATOM 735 2HB ASN 164 6.884-9.286 3.967 1.00 0.00 ATOM 736 QB ASN 164 6.983-9.897 3.340 1.00 0.00 ATOM 737 CG ASN 164 8.851-9.431 3.178 1.00 0.00 ATOM 738 OD1 ASN 164 9.530-10.449 3.233 1.00 0.00 ATOM 739 ND2 ASN 164 9.376-8.215 3.263 1.00 0.00 ATOM 740 1HD2 ASN 164 8. 765-7.448 3.237 1.00 0.00 ATOM 741 2HD2 ASN 164 10.347-8.131 3.288 1.00 0.00 ATOM 742 QD2 ASN 164 9.556-7.790 3.262 1.00 0.00 ATOM 743 C ASN 164 6. 410-7.220 2.653 1.00 0.00 ATOM 744 O ASN 164 7.259-6.417 3.035 1.00 0.00 ATOM 745 N LEU 165 5.105-7.016 2.801 1.00 0.00 ATOM 746 H LEU 165 4.479-7.693 2.472 1.00 0.00 ATOM 747 CA LEU 165 4.578-5.804 3.435 1.00 0.00 ATOM 748 HA LEU 165 5.083-4.951 3.005 1.00 0.00 ATOM 749 CB LEU 165 3.077-5.671 3.172 1.00 0.00 ATOM 750 1HB LEU 165 2.570-5.573 4.120 1.00 0.00 ATOM 751 2HB LEU 165 2.733-6.574 2.688 1.00 0.00 ATOM 752 QB LEU 165 2.651-6.074 3.404 1.00 0.00 ATOM 753 CG LEU 165 2.680-4.488 2.311 1.00 0.00 ATOM 754 HG LEU 165 3.188-3.602 2.665 1.00 0.00 ATOM 755 QD1 LEU 165 3.190-4.784 0.534 1.00 0.00 ATOM 756 QD2 LEU 165 0.828-4.191 2.434 1.00 0.00 ATOM 757 CD1 LEU 165 3.094-4.728 0.877 1.00 0.00 ATOM. 758 1HD1 LEU 165 3.874-4. 033 0.605 1.00 0.00 ATOM 759 2HD1 LEU 165 2.241-4.582 0.227 1.00 0.00 ATOM 760 3HD1 LEU 165 3.457-5.738 0.770 1.00 0.00 ATOM 761 CD2 LEU 165 1.184-4.248 2.411 1.00 0.00 ATOM 762 1HD2 LEU 165 0.941-3.298 1.958 1.00 0.00 ATOM 763 2HD2 LEU 165 0.888-4.237 3.449 1.00 0.00 ATOM 764 3HD2 LEU 165 0.657-5.037 1.894 1.00 0.00 ATOM 765 QQD LEU 165 2.009-4.488 1.484 1.00 0.00 ATOM 766 C LEU 165 4.819-5.793 4.932 1.00 0.00 ATOM 767 O LEU 165 4.449-6.728 5. 639 1.00 0.00 ATOM 768 N HIS+ 166 5.420-4.714 5.401 1.00 0.00 ATOM 769 H HIS+ 166 5.676-3.999 4.778 1.00 0.00 ATOM 770 CA HIS+ 166 5.698-4.543 6.813 1.00 0.00 ATOM 771 HA HIS+ 166 5.408-5.451 7.323 1.00 0.00 ATOM 772 CB HIS+ 166 7.198-4.301 7.027 1.00 0.00 ATOM 773 1HB HIS+ 166 7.486-3.405 6.495 1.00 0.00 ATOM 774 2HB HIS+ 166 7.751-5.139 6.633 1.00 0.00 ATOM 775 QB HIS+ 166 7.618-4.272 6.564 1.00 0.00 ATOM 776 CG HIS+ 166 7.590-4.126 8.460 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.530-5.137 9.394 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.042-3.036 9.115 1.00 0.00 ATOM 779 1HD HIS+ 166 7.232-6.056 9.227 1.00 0.00 ATOM 780 CE1 HIS+ 166 7.929-4.670 10.566 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.247-3.394 10.422 1.00 0.00 ATOM 782 2HD HIS+ 166 8.194-2.050 8.686 1.00 0.00 ATOM 783 1HE HIS+ 166 7.985-5.235 11.485 1.00 0.00 ATOM 784 2HE HIS+ 166 8.361-2.759 11.160 1.00 0.00

ATOM 785 C HIS+ 166 4.878-3.378 7.370 1.00 0.00 ATOM 786 O HIS+ 166 4.206-3.516 8.392 1.00 0.00 ATOM 787 N ASP 167 4.936-2.231 6.690 1.00 0.00 ATOM 788 H ASP 167 5.490-2.182 5.879 1.00 0.00 ATOM 789 CA ASP 167 4.201-1.040 7.132 1.00 0.00 ATOM 790 HA ASP 167 3. 657-1.307 8.026 1.00 0.00 ATOM 791 CB ASP 167 5.158 0.115 7.469 1.00 0.00 ATOM 792 1HB ASP 167 4.731 0.697 8.272 1.00 0.00 ATOM 793 2HB ASP 167 5.264 0.745 6.599 1.00 0.00 ATOM 794 QB ASP 167 4.997 0.721 7.435 1.00 0.00 ATOM 795 CG ASP 167 6.538-0.339 7.892 1.00 0.00 ATOM 796 OD1 ASP 167 7.337-0.727 7.011 1.00 0.00 ATOM 797 OD2 ASP 167 6.828-0.297 9.105 1. 00 0.00 ATOM 798 C ASP 167 3.205-0.555 6.080 1.00 0.00 ATOM 799 O ASP 167 3.552 0.221 5.196 1.00 0.00 ATOM 800 N TYR 168 1.964-1.002 6.189 1.00 0.00 ATOM 801 H TYR 168 1.741-1.607 6.925 1.00 0.00 ATOM 802 CA TYR 168 0.907-0.589 5.261 1.00 0.00 ATOM 803 HA TYR 168 1.375-0.283 4.326 1.00 0.00 ATOM 804 CB TYR 168-0.057-1.747 4.985 1.00 0.00 ATOM 805 1HB TYR 168 0.451-2.494 4.399 1.00 0.00 ATOM 806 2HB TYR 168-0.901-1.373 4.423 1.00 0.00 ATOM 807 QB TYR 168-0.225-1.934 4.411 1.00 0.00 ATOM 808 QD TYR 168-0.658-2.491 6.383 1.00 0.00 ATOM 809 QE TYR 168-1.536-3.559 8.415 1.00 0.00 ATOM 810 QR TYR 168-1.097-3.025 7.399 1.00 0.00 ATOM 811 CG TYR 168-0.596-2.413 6.236 1.00 0.00 ATOM 812 CD1 TYR 168-1.900-2.185 6.658 1.00 0.00 ATOM 813 1HD TYR 168-2.530-1.527 6.079 1. 00 0.00 ATOM 814 CE1 TYR 168-2.396-2.783 7.800 1.00 0.00 ATOM 815 1HE TYR 168-3.412-2.594 8.111 1.00 0.00 ATOM 816 CZ TYR 168-1.589-3.621 8.536 1.00 0.00 ATOM 817 CE2 TYR 168-0.292-3.866 8.140 1.00 0.00 ATOM 818 2HE TYR 168 0.341-4.523 8.719 1.00 0.00 ATOM 819 CD2 TYR 168 0.198-3.265 6.998 1.00 0.00 ATOM 820 2HD TYR 168 1.215-3.454 6.687 1.00 0.00 ATOM 821 OH TYR 168-2.083-4.220 9.670 1.00 0.00 ATOM 822 HH TYR 168-1.639-3.861 10.443 1.00 0.00 ATOM 823 C TYR 168 0.134 0.602 5.820 1.00 0.00 ATOM 824 O TYR 168 0.075 0.810 7.031 1.00 0.00 ATOM 825 N GLY 169-0.470 1.359 4.926 1.00 0.00 ATOM 826 H GLY 169-0.390 1.127 3.976 1.00 0.00 ATOM 827 CA GLY 169-1. 249 2.515 5.313 1.00 0.00 ATOM 828 1HA GLY 169-0.596 3.371 5.396 1.00 0.00 ATOM 829 2HA GLY 169-1.713 2.326 6.270 1.00 0.00 ATOM 830 QA GLY 169-1.155 2.848 5.833 1.00 0.00 ATOM 831 C GLY 169-2.314 2.804 4.288 1.00 0.00 ATOM 832 O GLY 169-2.146 2.466 3.124 1.00 0.00 ATOM 833 N MET 170-3.410 3.411 4.703 1.00 0.00 ATOM 834 H MET 170-3.496 3.657 5.647 1.00 0.00 ATOM 835 CA MET 170-4.498 3.725 3.783 1.00 0.00 ATOM 836 HA MET 170-4. 218 3.381 2.785 1.00 0.00 ATOM 837 CB MET 170-5.797 3.039 4.232 1.00 0.00 ATOM 838 1HB MET 170-6.630 3.664 3.941 1.00 0.00 ATOM 839 2HB MET 170-5.787 2.960 5.307 1.00 0.00 ATOM 840 QB MET 170-6.209 3.312 4.624 1.00 0.00 ATOM 841 CG MET 170-6.033 1.644 3.663 1.00 0.00 ATOM 842 1HG MET 170-6.765 1.718 2.872 1.00 0.00 ATOM 843 2HG MET 170-6.424 1.015 4.448 1.00 0.00 ATOM 844 QG MET 170-6.595 1.366 3.660 1.00 0.00 ATOM 845 SD MET 170-4.549 0.870 3.000 1.00 0.00 ATOM 846 QE MET 170-4.325-0.816 4. 314 1.00 0.00 ATOM 847 CE MET 170-4.362-0.533 4.094 1.00 0.00 ATOM 848 1HE MET 170-4.837-1.399 3.654 1.00 0.00 ATOM 849 2HE MET 170-4.825-0.313 5.045 1.00 0.00 ATOM 850 3HE MET 170-3.312-0.736 4.243 1. 00 0. 00 ATOM 851 C MET 170-4.721 5.228 3.748 1.00 0.00 ATOM 852 O MET 170-4.747 5.883 4.790 1. 00 0. 00 ATOM 853 N LEU 171-4.879 5.770 2.555 1.00 0. 00 ATOM 854 H LEU 171-4.847 5.194 1.760 1.00 0.00 ATOM 855 CA LEU 171-5.095 7.201 2.395 1.00 0. 00 ATOM 856 HA LEU 171-5.213 7.629 3.379 1.00 0. 00

ATOM 857 CB LEU 171-3.881 7.844 1.714 1.00 0.00 ATOM 858 1HB LEU 171-3.544 8.665 2.328 1.00 0.00 ATOM 859 2HB LEU 171-4.197 8.238 0.758 1.00 0.00 ATOM 860 QB LEU 171-3.871 8.451 1.543 1.00 0.00 ATOM 861 CG LEU 171-2.696 6.904 1.481 1.00 0.00 ATOM 862 HG LEU 171-3.040 5.881 1.538 1.00 0.00 ATOM 863 QD1 LEU 171-1.956 7.170-0.228 1.00 0.00 ATOM 864 QD2 LEU 171-1.390 7.149 2.809 1.00 0.00 ATOM 865 CD1 LEU 171-2.100 7.119 0.100 1.00 0.00 ATOM 866 1HD1 LEU 171-1.023 7.184 0.179 1.00 0.00 ATOM 867 2HD1 LEU 171-2.483 8.037-0.323 1.00 0.00 ATOM 868 3HD1 LEU 171-2.362 6.290-0.540 1.00 0.00 ATOM 869 CD2 LEU 171-1.641 7.102 2.555 1.00 0.00 ATOM 870 1HD2 LEU 171-0. 712 7.408 2.094 1.00 0.00 ATOM 871 2HD2 LEU 171-1.489 6.174 3.087 1.00 0.00 ATOM 872 3HD2 LEU 171-1.968 7.864 3.246 1.00 0.00 ATOM 873 QQD LEU 171-1.673 7.159 1.290 1.00 0.00 ATOM 874 C LEU 171-6.353 7.476 1.582 1.00 0.00 ATOM 875 O LEU 171-7. 116 6.555 1.286 1.00 0.00 ATOM 876 N LEU 172-6.536 8.753 1.222 1.00 0.00 ATOM 877 H LEU 172-5.863 9.410 1.498 1.00 0.00 ATOM 878 CA LEU 172-7.677 9.226 0.422 1.00 0.00 ATOM 879 HA LEU 172-7.819 10.271 0.651 1.00 0.00 ATOM 880 CB LEU 172-7.365 9.099-1.071 1.00 0.00 ATOM 881 1HB LEU 172-8.247 8.725-1.569 1.00 0.00 ATOM 882 2HB LEU 172-6.571 8.376-1.193 1.00 0.00 ATOM 883 QB LEU 172-7.409 8.550-1.381 1.00 0.00 ATOM 884 CG LEU 172-6.945 10.401-1.758 1.00 0.00 ATOM 885 HG LEU 172-7.635 11.186-1.484 1.00 0.00 ATOM 886 QD1 LEU 172-5.225 10.924-1.206 1.00 0.00 ATOM 887 QD2 LEU 172-6.995 10.206-3.625 1.00 0.00 ATOM 888 CD1 LEU 172-5.555 10.824-1.310 1.00 0.00 ATOM 889 1HD1 LEU 172-5.055 11.332-2.123 1.00 0.00 ATOM 890 2HD1 LEU 172-4.984 9.951-1.029 1.00 0.00 ATOM 891 3HD1 LEU 172-5.634 11.490-0.465 1.00 0.00 ATOM 892 CD2 LEU 172-6.987 10.243-3.268 1.00 0.00 ATOM 893 1HD2 LEU 172-7.422 9.288-3.519 1.00 0.00 ATOM 894 2HD2 LEU 172-5.981 10.295-3.661 1.00 0.00 ATOM 895 3HD2 LEU 172-7.581 11.036-3.696 1.00 0.00 ATOM 896 QQD LEU 172-6.110 10.565-2.416 1.00 0.00 ATOM 897 C LEU 172-8.977 8.488 0.736 1.00 0.00 ATOM 898 0 LEU 172-9.421 7.649-0.048 1.00 0.00 ATOM 899 N PRO 173-9.612 8.792 1.880 1.00 0.00 ATOM 900 CD PRO 173-9.165 9.787 2.873 1.00 0.00 ATOM 901 CA PRO 173-10. 869 8.148 2.275 1.00 0.00 ATOM 902 HA PRO 173-10.719 7.105 2.515 1.00 0. 00 ATOM 903 CB PRO 173-11.286 8.912 3.535 1.00 0.00 ATOM 904 1HB PRO 173-11.741 8.229 4.239 1.00 0.00 ATOM 905 2HB PRO 173-11.991 9.687 3.271 1.00 0. 00 ATOM 906 QB PRO 173-11.866 8.958 3.755 1.00 0.00 ATOM 907 CG PRO 173-10.019 9.484 4.072 1.00 0.00 ATOM 908 1HG PRO 173-9.530 8.761 4.709 1.00 0.00 ATOM 909 2HG PRO 173-10.230 10.389 4.623 1.00 0. 00 ATOM 910 QG PRO 173-9.880 9.575 4.666 1.00 0.00 ATOM 911 1HD PRO 173-8. 119 9.653 3.109 1.00 0.00 ATOM 912 2HD PRO 173-9.349 10.792 2.522 1.00 0.00 ATOM 913 QD PRO 173-8.734 10.222 2.815 1.00 0.00 ATOM 914 C PRO 173-11.946 8.271 1.201 1.00 0.00 ATOM 915 O PRO 173-12.060 9.297 0.526 1.00 0.00 ATOM 916 N CYS 174-12.732 7.221 1.049 1.00 0.00 ATOM 917 H CYS 174-12.594 6.434 1.623 1.00 0.00 ATOM 918 CA CYS 174-13.805 7.202 0.068 1.00 0.00 ATOM 919 HA CYS 174-13.705 8.079-0.554 1.00 0.00 ATOM 920 CB CYS 174-13.713 5.951-0.805 1.00 0.00 ATOM 921 1HB CYS 174-14.033 5.096-0.228 1.00 0.00 ATOM 922 2HB CYS 174-12.687 5.809-1.111 1.00 0.00 ATOM 923 QB CYS 174-13.360 5.452-0.670 1.00 0.00 ATOM 924 SG CYS 174-14.733 6.019-2.312 1.00 0.00 ATOM 925 C CYS 174-15.148 7.248 0.773 1.00 0.00 ATOM 926'0 CYS 174-16.058 7.962 0. 360 1.00 0.00 ATOM 927 N GLY 175-15.253 6.491 1.854 1.00 0.00 ATOM 928 H GLY 175-14.482 5.953 2.142 1.00 0.00

ATOM 929 CA GLY 175-16.473 6.460 2.628 1.00 0.00 ATOM 930 1HA GLY 175-17. 024 5.565 2.387 1.00 0.00 ATOM 931 2HA GLY 175-17.073 7.324 2.381 1.00 0.00 ATOM 932 QA GLY 175-17.049 6.444 2.384 1.00 0.00 ATOM 933 C GLY 175-16.176 6.475 4.106 1.00 0.00 ATOM 934 O GLY 175-15. 113 6.930 4.519 1.00 0.00 ATOM 935 N ILE 176-17. 104 5.968 4.900 1.00 0.00 ATOM 936 H ILE 176-17.928 5.613 4.509 1.00 0.00 ATOM 937 CA ILE 176-16.923 5.916 6.343 1.00 0.00 ATOM 938 HA ILE 176-16. 535 6.871 6. 669 1.00 0.00 ATOM 939 CB ILE 176-18.265 5.657 7.062 1.00 0.00 ATOM 940 HB ILE 176-18.441 4.593 7.062 1.00 0.00 ATOM 941 QG2 ILE 176-18. 188 6.237 8.849 1.00 0.00 ATOM 942 CG2 ILE 176-18. 202 6.126 8.507 1.00 0.00 ATOM 943 1HG2 ILE 176-17.251 5.845 8.936 1.00 0.00 ATOM 944 2HG2 ILE 176-19.002 5.667 9.070 1.00 0.00 ATOM 945 3HG2 ILE 176-18. 309 7.200 8.541 1.00 0.00 ATOM 946 CG1 ILE 176-19.414 6.353 6.332 1.00 0.00 ATOM 947 1HG1 ILE 176-19.058 6.723 5.382 1.00 0.00 ATOM 948 2HG1 ILE 176-19.760 7.183 6.930 1.00 0.00 ATOM 949 QG1 ILE 176-19.409 6.953 6.156 1.00 0. 00 ATOM 950 QD1 ILE 176-20.878 5.233 6.006 1.00 0.00 ATOM 951 CD1 ILE 176-20.596 5.448 6.068 1.00 0.00 ATOM 952 1HD1 ILE 176-21.052 5.715 5.126 1.00 0.00 ATOM 953 2HD1 ILE 176-21.319 5.562 6.863 1.00 0.00 ATOM 954 3HD1 ILE 176-20.263 4.421 6.030 1.00 0.00 ATOM 955 C ILE 176-15.926 4.816 6.720 1.00 0.00 ATOM 956 O ILE 176-15.254 4.896 7.746 1.00 0.00 ATOM 957 N ASP 177-15.851 3.787 5.879 1.00 0.00 ATOM 958 H ASP 177-16.419 3.785 5.086 1.00 0.00 ATOM 959 CA ASP 177-14.954 2.654 6.110 1.00 0.00 ATOM 960 HA ASP 177-14. 307 2.903 6.938 1.00 0. 00 ATOM 961 CB ASP 177-15.796 1.415 6.483 1.00 0.00 ATOM 962 1HB ASP 177-16.753 1.481 5.988 1.00 0.00 ATOM 963 2HB ASP 177-15.955 1.412 7.550 1.00 0.00 ATOM 964 QB ASP 177-16.354 1.446 6.769 1.00 0.00 ATOM 965 CG ASP 177-15. 156 0.091 6.104 1.00 0.00 ATOM 966 OD1 ASP 177-14.292-0.389 6.859 1.00 0.00 ATOM 967 OD2 ASP 177-15. 527-0. 473 5.051 1.00 0.00 ATOM 968 C ASP 177-14.093 2.373 4.870 1.00 0.00 ATOM 969 O ASP 177-13.121 1.616 4.914 1.00 0.00 ATOM 970 N LYS+ 178-14.460 2.981 3.751 1.00 0.00 ATOM 971 H LYS+ 178-15.240 3.569 3.761 1.00 0.00 ATOM 972 CA LYS+ 178-13. 734 2.768 2.503 1.00 0.00 ATOM 973 HA LYS+ 178-13. 246 1.808 2.566 1.00 0.00 ATOM 974 CB LYS+ 178-14.710 2.748 1.323 1.00 0.00 ATOM 975 1HB LYS+ 178-14. 198 2.363 0.456 1.00 0.00 ATOM 976 2HB LYS+ 178-15.027 3.761 1.121 1.00 0.00 ATOM 977 QB LYS+ 178-14. 613 3.062 0.788 1.00 0.00 ATOM 978 CG LYS+ 178-15.952 1.901 1.566 1.00 0.00 ATOM 979 1HG LYS+ 178-16. 699 2.152 0.825 1.00 0.00 ATOM 980 2HG LYS+ 178-16. 335 2.117 2.553 1.00 0.00 ATOM 981 QG LYS+ 178-16.517 2.134 1.689 1. 00 0. 00 ATOM 982 CD LYS+ 178-15.645 0.414 1.474 1.00 0.00 ATOM 983 1HD LYS+ 178-14.637 0.243 1.825 1.00 0.00 ATOM 984 2HD LYS+ 178-15.728 0.102 0.442 1.00 0.00 ATOM 985 QD LYS+ 178-15.183 0.172 1.133 1.00 0.00 ATOM 986 CE LYS+ 178-16.610-0.404 2.319 1.00 0.00 ATOM 987 1HE LYS+ 178-17.574-0.419 1.832 1.00 0.00 ATOM 988 2HE LYS+ 178-16.703 0.066 3.290 1.00 0.00 ATOM 989 QE LYS+ 178-17.139-0.177 2.561 1.00 0.00 ATOM 990 NZ LYS+ 178-16.139-1.803 2.511 1.00 0.00 ATOM 991 1HZ LYS+ 178-15.873-2.225 1.602 1.00 0.00 ATOM 992 2HZ LYS+ 178-16.890-2.375 2.944 1.00 0.00 ATOM 993 3HZ LYS+ 178-15.306-1.816 3.148 1.00 0. 00 ATOM 994 QZ LYS+ 178-16.023-2.139 2.565 1.00 0.00 ATOM 995 C LYS+ 178-12.667 3.818 2.258 1.00 0.00 ATOM 996 O LYS+ 178-12.850 4.996 2.552 1.00 0.00 ATOM 997 N PHE 179-11.558 3.368 1.687 1.00 0. 00 ATOM 998 H PHE 179-11.496 2.414 1.462 1. 00 0. 00 ATOM 999 CA PHE 179-10.440 4.234 1.358 1.00 0. 00 ATOM 1000 HA PHE 179-10. 705 5.249 1.613 1.00 0. 00

ATOM 1001 CB PHE 179-9.187 3.824 2. 128 1.00 0.00 ATOM 1002 1HB PHE 179-8.444 4.579 1.989 1.00 0.00 ATOM 1003 2HB PHE 179-8.813 2.897 1.723 1.00 0.00 ATOM 1004 QB PHE 179-8.629 3.738 1.856 1.00 0.00 ATOM 1005 QD PHE 179-9.420 3.619 3.767 1.00 0.00 ATOM 1006 QE PHE 179-9.760 3.324 6.185 1.00 0.00 ATOM 1007 QR PHE 179-9.658 3.413 5.461 1.00 0.00 ATOM 1008 CG PHE 179-9.396 3.640 3.604 1.00 0.00 ATOM 1009 CD1 PHE 179-9.202 4.697 4.479 1.00 0.00 ATOM 1010 1HD PHE 179-8.901 5.658 4.090 1.00 0.00 ATOM 1011 CE1 PHE 179-9.392 4.533 5.837 1.00 0.00 ATOM 1012 1HE PHE 179-9.238 5.366 6.508 1.00 0.00 ATOM 1013 CZ PHE 179-9.779 3.306 6.336 1.00 0.00 ATOM 1014 HZ PHE 179-9.930 3.176 7.398 1.00 0.00 ATOM 1015 CE2 PHE 179-9.975 2.244 5.475 1.00 0.00 ATOM 1016 2HE PHE 179-10.282 1. 283 5.862 1.00 0.00 ATOM 1017 CD2 PHE 179-9.784 2.413 4.118 1.00 0.00 ATOM 1018 2HD PHE 179-9.939 1.581 3.445 1.00 0.00 ATOM 1019 C PHE 179-10.144 4.144-0.125 1.00 0.00 ATOM 1020 O PHE 179-10.852 3.459-0.859 1.00 0.00 ATOM 1021 N ARG+ 180-9.082 4.811-0.552 1.00 0.00 ATOM 1022 H ARG+ 180-8.549 5.322 0.095 1.00 0.00 ATOM 1023 CA ARG+ 180-8.665 4.788-1.949 1.00 0.00 ATOM 1024 HA ARG+ 180-9.042 3.879-2.398 1.00 0.00 ATOM 1025 CB ARG+ 180-9.226 5.993-2.714 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.842 5.964-3.724 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.886 6.899-2.240 1.00 0.00 ATOM 1028 QB ARG+ 180-8.864 6.431-2.982 1.00 0.00 ATOM 1029 CG ARG+ 180-10.741 6.026-2.784 1.00 0.00 ATOM 1030 1HG ARG+ 180-11.137 6.020-1.780 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.084 5. 147-3.314 1.00 0.00 ATOM 1032 QG ARG+ 180-11.111 5.583-2.547 1.00 0.00 ATOM 1033 CD ARG+ 180-11.242 7.262-3.509 1.00 0.00 ATOM 1034 1HD ARG+ 180-12.097 6.985-4.111 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.456 7.631-4.151 1.00 0.00 ATOM 1036 QD ARG+ 180-11.277 7.308-4.131 1.00 0.00 ATOM 1037 NE ARG+ 180-11.636 8.318-2.580 1.00 0.00 ATOM 1038 HE ARG+ 180-11.240 8.301-1.677 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.504 9.282-2.884 1.00 0.00 ATOM 1040 NH1 ARG+ 180-13.025 9.344-4.106 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.764 8.667-4.798 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.677 10.065-4.341 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.221 9.366-4.570 1.00 0.00 ATOM 1044 NH2 ARG+ 180-12.842 10.183-1.969 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.444 10.136-1.044 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.492 10.909-2.192 1.00 0.00 ATOM 1047 QH2 ARG+ 180-12.968 10.522-1.618 1.00 0.00 ATOM 1048 C ARG+ 180-7.144 4.794-2.052 1.00 0.00 ATOM 1049 O ARG+ 180-6.583 4.470-3.087 1.00 0. 00 ATOM 1050 N GLY 181-6.475 5.175-0.978 1.00 0.00 ATOM 1051 H GLY 181-6.961 5.429-0.164 1.00 0.00 ATOM 1052 CA GLY 181-5. 028 5.230-1.007 1.00 0.00 ATOM 1053 1HA GLY 181-4.707 6. 183-0.610 1.00 0.00 ATOM 1054 2HA GLY 181-4. 701 5.155-2.034 1.00 0.00 ATOM 1055 QA GLY 181-4.704 5.669-1.322 1.00 0.00 ATOM 1056 C GLY 181-4.374 4.127-0.212 1.00 0.00 ATOM 1057 O GLY 181-4.968 3.588 0.721 1.00 0.00 ATOM 1058 N VAL 182-3.141 3.805-0.581 1.00 0.00 ATOM 1059 H VAL 182-2. 733 4.287-1.320 1.00 0.00 ATOM 1060 CA VAL 182-2. 368 2.771 0.087 1.00 0.00 ATOM 1061 HA VAL 182-2.752 2.664 1.093 1.00 0.00 ATOM 1062 CB VAL 182-2.468 1.398-0.629 1.00 0.00 ATOM 1063 HB VAL 182-1.638 1.320-1.318 1.00 0.00 ATOM 1064 QG1 VAL 182-2.324-0.004 0.612 1.00 0.00 ATOM 1065 QG2 VAL 182-4.065 1.233-1.615 1.00 0.00 ATOM 1066 CG1 VAL 182-2.351 0.265 0.374 1.00 0.00 ATOM 1067 1HG1 VAL 182-2.611 0.626 1.359 1.00 0.00 ATOM 1068 2HG1 VAL 182-1.337-0.106 0.382 1.00 0.00 ATOM 1069 3HG1 VAL 182-3.024-0.533 0. 095 1.00 0. 00 ATOM 1070 CG2 VAL 182-3.760 1.264-1.427 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.961 0.220-1.613 1.00 0.00 ATOM 1072 2HG2 VAL 182-3.658 1.784-2.367 1.00 0.00

ATOM 1073 3HG2 VAL 182-4.576 1.694-0.864 1.00 0.00 ATOM 1074 QQG VAL 182-3.195 0.614-0.501 1.00 0.00 ATOM 1075 C VAL 182-0.891 3.173 0.158 1.00 0.00 ATOM 1076 O VAL 182-0.274 3.480-0.860 1.00 0.00 ATOM 1077 N GLU 183-0.340 3.155 1.364 1.00 0.00 ATOM 1078 H GLU 183-0.899 2.889 2.130 1.00 0.00 ATOM 1079 CA GLU 183 1.058 3.496 1.610 1.00 0.00 ATOM 1080 HA GLU 183 1.549 3.656 0.658 1.00 0.00 ATOM 1081 CB GLU 183 1.133 4.776 2.453 1.00 0.00 ATOM 1082 1HB GLU 183 0.464 4.675 3.295 1.00 0.00 ATOM 1083 2HB GLU 183 0.807 5.608 1.849 1.00 0.00 ATOM 1084 QB GLU 183 0.635 5.141 2.572 1.00 0.00 ATOM 1085 CG GLU 183 2.516 5.103 2.991 1.00 0.00 ATOM 1086 1HG GLU 183 3.179 5.296 2.161 1.00 0.00 ATOM 1087 2HG GLU 183 2.880 4.258 3.556 1.00 0.00 ATOM 1088 QG GLU 183 3.029 4.777 2.858 1.00 0.00 ATOM 1089 CD GLU 183 2.500 6.318 3.894 1.00 0.00 ATOM 1090 OE1 GLU 183 3.533 7.009 3.974 1.00 0.00 ATOM 1091 OE2 GLU 183 1.445 6.590 4.502 1.00 0.00 ATOM 1092 C GLU 183 1.717 2.329 2.339 1.00 0.00 ATOM 1093 O GLU 183 1.623 2.212 3.555 1.00 0.00 ATOM 1094 N PHE 184 2.332 1.431 1.594 1.00 0.00 ATOM 1095 H PHE 184 2.344 1.542 0.627 1.00 0.00 ATOM 1096 CA PHE 184 2.940 0.248 2.191 1.00 0.00 ATOM 1097 HA PHE 184 2.771 0.307 3.254 1.00 0.00 ATOM 1098 CB PHE 184 2.281-1.032 1.665 1.00 0.00 ATOM 1099 1HB PHE 184 1.353-1.199 2.193 1.00 0.00 ATOM 1100 2HB PHE 184 2.943-1.863 1.863 1.00 0.00 ATOM 1101 QB PHE 184 2.148-1.531 2.028 1.00 0.00 ATOM 1102 QD PHE 184 1.951-1.036 0. 011 1.00 0.00 ATOM 1103 QE PHE 184 1.450-1.107-2.394 1.00 0.00 ATOM 1104 QR PHE 184 1.599-1.089-1.672 1.00 0.00 ATOM 1105 CG PHE 184 1.986-1.035 0.181 1.00 0.00 ATOM 1106 CD1 PHE 184 2.638-1.925-0.656 1.00 0.00 ATOM 1107 1HD PHE 184 3.375-2.596-0.241 1.00 0.00 ATOM 1108 CE1 PHE 184 2.356-1.969-2.006 1.00 0.00 ATOM 1109 1HE PHE 184 2.874-2.671-2.643 1.00 0.00 ATOM 1110 CZ PHE 184 1.419-1.115-2.542 1.00 0.00 ATOM 1111 HZ PHE 184 1.192-1.157-3.595 1.00 0.00 ATOM 1112 CE2 PHE 184 0.763-0.216-1.727 1.00 0.00 ATOM 1113 2HE PHE 184 0.027 0.457-2.144 1.00 0.00 ATOM 1114 CD2 PHE 184 1.042-0.181-0.373 1.00 0.00 ATOM 1115 2HD PHE 184 0.528 0.524 0.264 1.00 0.00 ATOM 1116 C PHE 184 4.434 0.158 1.948 1.00 0.00 ATOM 1117 O PHE 184 4.923 0.463 0. 868 1.00 0.00 ATOM 1118 N VAL 185 5.146-0.301 2.963 1.00 0.00 ATOM 1119 H VAL 185 4.687-0.547 3.794 1.00 0.00 ATOM 1120 CA VAL 185 6.582-0.474 2.879 1.00 0.00 ATOM 1121 HA VAL 185 6.913-0.066 1.934 1.00 0.00 ATOM 1122 CB VAL 185 7.303 0.279 4.022 1.00 0.00 ATOM 1123 HB VAL 185 7.424-0.398 4.861 1.00 0.00 ATOM 1124 QG1 VAL 185 9.002 0.856 3.478 1.00 0.00 ATOM 1125 QG2 VAL 185 6.286 1.754 4.601 1.00 0.00 ATOM 1126 CG1 VAL 185 8.678 0.744 3.581 1.00 0.00 ATOM 1127 1HG1 VAL 185 8.899 0.339 2.605 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.416 0.404 4.292 1.00 0.00 ATOM 1129 3HG1 VAL 185 8.693 1.824 3.536 1.00 0.00 ATOM 1130 CG2 VAL 185 6.482 1.472 4.489 1.00 0.00 ATOM 1131 1HG2 VAL 185 6.970 2.387 4.189 1.00 0.00 ATOM 1132 2HG2 VAL 185 6.393 1.448 5.566 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.497 1.427 4.047 1.00 0.00 ATOM 1134 QQG VAL 185 7.644 1.305 4.039 1.00 0.00 ATOM 1135 C VAL 185 6.924-1.966 2.920 1.00 0.00 ATOM 1136 O VAL 185 6.828-2.610 3.962 1.00 0.00 ATOM 1137 N CYS 186 7.301-2.518 1.772 1.00 0.00 ATOM 1138 H CYS 186 7.346-1.959 0.964 1.00 0.00 ATOM 1139 CA CYS 186 7.640-3.935 1.681 1.00 0.00 ATOM 1140 HA CYS 186 7.423-4.384 2.641 1.00 0.00 ATOM 1141 CB CYS 186 6.785-4.631 0.608 1.00 0.00 ATOM 1142 1HB CYS 186 5.748-4.584 0.907 1.00 0.00 ATOM 1143 2HB CYS 186 7.083-5.666 0.545 1.00 0.00 ATOM 1144 QB CYS 186 6.415-5.125 0.726 1.00 0.00

ATOM 1145 SG CYS 186 6. 910-3.927-1.068 1.00 0.00 ATOM 1146 C CYS 186 9.127-4.116 1.391 1.00 0.00 ATOM 1147 O CYS 186 9.667-3.483 0.497 1.00 0.00 ATOM 1148 N CYS 187 9.794-4.974 2.152 1.00 0.00 ATOM 1149 H CYS 187 9.320-5.461 2.860 1.00 0.00 ATOM 1150 CA CYS 187 11.231-5.193 1.961 1.00 0.00 ATOM 1151 HA CYS 187 11.644-4.290 1.543 1.00 0.00 ATOM 1152 CB CYS 187 11.924-5.479 3.297 1.00 0.00 ATOM 1153 1HB CYS 187 12.739-6.169 3.129 1.00 0.00 ATOM 1154 2HB CYS 187 11.214-5.932 3.973 1.00 0.00 ATOM 1155 QB CYS 187 11.976-6.051 3.551 1.00 0.00 ATOM 1156 SG CYS 187 12.605-4.005 4.122 1.00 0.00 ATOM 1157 C CYS 187 11.510-6.339 1.009 1.00 0.00 ATOM 1158 O CYS 187 10.788-7.330 0.996 1.00 0.00 ATOM 1159 N PRO 188 12.572-6.204 0.194 1.00 0.00 ATOM 1160 CD PRO 188 13.473-5.033 0.151 1.00 0.00 ATOM 1161 CA PRO 188 12.960-7.232-0.772 1.00 0.00 ATOM 1162 HA PRO 188 12.125-7.527-1.392 1.00 0.00 ATOM 1163 CB PRO 188 14.023-6.544-1.632 1.00 0.00 ATOM 1164 1HB PRO 188 13.564-6.142-2.522 1.00 0.00 ATOM 1165 2HB PRO 188 14.782-7.263-1.907 1.00 0.00 ATOM 1166 QB PRO 188 14. 173-6.703-2.215 1.00 0.00 ATOM 1167 CG PRO 188 14.582-5.463-0.771 1.00 0.00 ATOM 1168 1HG PRO 188 14.901-4.633-1.386 1.00 0.00 ATOM 1169 2HG PRO 188 15.415-5.846-0.200 1.00 0.00 ATOM 1170 QG PRO 188 15.158-5.240-0.793 1.00 0. 00 ATOM 1171 1HD PRO 188 12.963-4.169-0.251 1.00 0.00 ATOM 1172 2HD PRO 188 13.865-4.814 1.133 1.00 0.00 ATOM 1173 QD PRO 188 13.414-4.492 0.441 1.00 0.00 ATOM 1174 C PRO 188 13.538-8.469-0.092 1.00 0.00 ATOM 1175 O PRO 188 14.542-8.386 0.625 1.00 0.00 ATOM 1176 N LEU 189 12.897-9.604-0.326 1.00 0.00 ATOM 1177 H LEU 189 12.107-9.593-0.909 1.00 0.00 ATOM 1178 CA LEU 189 13.327-10.869 0.242 1.00 0.00 ATOM 1179 HA LEU 189 14.286-10.715 0.714 1.00 0.00 ATOM 1180 CB LEU 189 12.321-11.355 1.289 1.00 0.00 ATOM 1181 1HB LEU 189 11.583-11.963 0.788 1.00 0.00 ATOM 1182 2HB LEU 189 11.827-10.494 1.713 1.00 0.00 ATOM 1183 QB LEU 189 11.705-11.229 1.250 1.00 0. 00 ATOM 1184 CG LEU 189 12.922-12.180 2.429 1. 00 0.00 ATOM 1185 HG LEU 189 13.650-12.866 2.020 1.00 0.00 ATOM 1186 QD1 LEU 189 13.801-11.064 3.659 1.00 0.00 ATOM 1187 QD2 LEU 189 11.588-13.185 3.290 1.00 0.00 ATOM 1188 CD1 LEU 189 13.633-11.277 3.424 1.00 0. 00 ATOM 1189 1HD1 LEU 189 14.044-10.425 2.904 1.00 0.00 ATOM 1190 2HD1 LEU 189 14.431-11.827 3.902 1.00 0.00 ATOM 1191 3HD1 LEU 189 12.930-10. 940 4.170 1.00 0.00 ATOM 1192 CD2 LEU 189 11.844-12.993 3.126 1.00 0.00 ATOM 1193 1HD2 LEU 189 12.221-13.357 4.069 1.00 0.00 ATOM 1194 2HD2 LEU 189 11.565-13.829 2.502 1.00 0.00 ATOM 1195 3HD2 LEU 189 10.979-12.369 3.300 1.00 0.00 ATOM 1196 QQD LEU 189 12.695-12.125 3.474 1.00 0.00 ATOM 1197 C LEU 189 13.477-11.911-0.862 1.00 0.00 ATOM 1198 OT1 LEU 189 13.988-13.013-0.575 1.00 0.00 ATOM 1199 OT2 LEU 189 13.074-11.616-2.008 1.00 0.00 TER ENDMDL MODEL 15 ATOM 1 N SER 124 13.187 12.257 6.390 1.00 0. 00 ATOM 2 CA SER 124 12.168 11.176 6.444 1.00 0.00 ATOM 3 HA SER 124 12.664 10.221 6.369 1.00 0.00 ATOM 4 CB SER 124 11.454 11.277 7.789 1.00 0.00 ATOM 5 1HB SER 124 11.371 10.294 8.229 1.00 0.00 ATOM 6 2HB SER 124 10.465 11.692 7.641 1.00 0.00 ATOM 7 QB SER 124 10.918 10.993 7.935 1.00 0.00 ATOM 8 OG SER 124 12.180 12.119 8.676 1.00 0.00 ATOM 9 HG SER 124 11.573 12.516 9.314 1.00 0.00 ATOM 10 C SER 124 11.178 11.321 5.303 1. 00 0. 00 ATOM 11 O SER 124 10.618 10.340 4.817 1.00 0.00 ATOM 12 1HT SER 124 12.910 12.978 5.689 1.00 0. 00 ATOM 13 2HT SER 124 14. 111 11.868 6.124 1.00 0.00 ATOM 14 3HT SER 124 13.266 12.712 7.323 1.00 0.00

ATOM 15 N ASP 125 10.984 12.561 4.891 1.00 0.00 ATOM 16 H ASP 125 11.473 13.289 5.332 1.00 0.00 ATOM 17 CA ASP 125 10.083 12.910 3.809 1.00 0.00 ATOM 18 HA ASP 125 9.104 12.527 4.047 1.00 0.00 ATOM 19 CB ASP 125 10.013 14.435 3.685 1.00 0.00 ATOM 20 1HB ASP 125 8.978 14.739 3.623 1.00 0.00 ATOM 21 2HB ASP 125 10.528 14.741 2.787 1.00 0.00 ATOM 22 QB ASP 125 9.753 14.740 3.205 1.00 0.00 ATOM 23 CG ASP 125 10.651 15.142 4.869 1.00 0.00 ATOM 24 OD1 ASP 125 9.919 15.806 5.624 1.00 0.00 ATOM 25 OD2 ASP 125 11.884 15.002 5.060 1.00 0.00 ATOM 26 C ASP 125 10.558 12.301 2.497 1.00 0.00 ATOM 27 O ASP 125 11. 709 12.483 2.096 1.00 0.00 ATOM 28 N ALA 126 9.667 11.579 1.838 1.00 0.00 ATOM 29 H ALA 126 8.767 11.475 2.215 1.00 0.00 ATOM 30 CA ALA 126 9.975 10.937 0.569 1.00 0.00 ATOM 31 HA ALA 126 10.594 11.609-0.008 1.00 0.00 ATOM 32 QB ALA 126 10.923 9.332 0.845 1.00 0.00 ATOM 33 CB ALA 126 10.743 9.639 0.792 1.00 0.00 ATOM 34 1HB ALA 126 11.050 9.577 1.826 1.00 0.00 ATOM 35 2HB ALA 126 11. 615 9.622 0.155 1.00 0.00 ATOM 36 3HB ALA 126 10.106 8.799 0.555 1.00 0.00 ATOM 37 C ALA 126 8.687 10.667-0.188 1.00 0.00 ATOM 38 O ALA 126 7.602 10.983 0.299 1.00 0.00 ATOM 39 N LEU 127 8.799 10.084-1.372 1.00 0.00 ATOM 40 H LEU 127 9.684 9.852-1.713 1.00 0.00 ATOM 41 CA LEU 127 7.621 9.787-2.171 1.00 0.00 ATOM 42 HA LEU 127 6.785 9.686-1.497 1.00 0.00 ATOM 43 CB LEU 127 7.340 10.946-3.141 1.00 0.00 ATOM 44 1HB LEU 127 7.867 10.746-4.062 1.00 0.00 ATOM 45 2HB LEU 127 7.743 11.850-2.709 1.00 0.00 ATOM 46 QB LEU 127 7.805 11.298-3.386 1.00 0.00 ATOM 47 CG LEU 127 5.862 11.200-3.484 1.00 0.00 ATOM 48 HG LEU 127 5.686 12.266-3.497 1.00 0.00 ATOM 49 QD1 LEU 127 5.448 10.532-5.192 1.00 0.00 ATOM 50 QD2 LEU 127 4.722 10.443-2.189 1.00 0.00 ATOM 51 CD1 LEU 127 5.528 10.661-4.865 1.00 0.00 ATOM 52 1HD1 LEU 127 5.865 9.637-4.942 1.00 0.00 ATOM 53 2HD1 LEU 127 6.021 11.260-5.615 1.00 0.00 ATOM 54 3HD1 LEU 127 4.459 10.700-5.017 1.00 0.00 ATOM 55 CD2 LEU 127 4.941 10.588-2.436 1.00 0.00 ATOM 56 1HD2 LEU 127 5.318 10.812-1.449 1.00 0.00 ATOM 57 2HD2 LEU 127 4.902 9.517-2.573 1.00 0.00 ATOM 58 3HD2 LEU 127 3.948 11.001-2.545 1.00 0.00 ATOM 59 QQD LEU 127 5.085 10.487-3.691 1.00 0.00 ATOM 60 C LEU 127 7.790 8.479-2.943 1.00 0.00 ATOM 61 O LEU 127 6.896 8.067-3.680 1.00 0.00 ATOM 62 N LEU 128 8.932 7.819-2.782 1.00 0.00 ATOM 63 H LEU 128 9.621 8.170-2.187 1.00 0.00 ATOM 64 CA LEU 128 9.162 6.572-3.491 1.00 0.00 ATOM 65 HA LEU 128 8.196 6.171-3.755 1.00 0.00 ATOM 66 CB LEU 128 9.951 6.841-4.777 1.00 0.00 ATOM 67 1HB LEU 128 11.002 6.732-4.554 1.00 0.00 ATOM 68 2HB LEU 128 9.769 7.863-5.077 1.00 0.00 ATOM 69 QB LEU 128 10.385 7.297-4.816 1.00 0.00 ATOM 70 CG LEU 128 9.613 5.924-5.962 1.00 0.00 ATOM 71 HG LEU 128 8.831 5.231-5.668 1.00 0.00 ATOM 72 QD1 LEU 128 8.965 6.938-7.406 1.00 0.00 ATOM 73 QD2 LEU 128 11.121 4.933-6.495 1.00 0.00 ATOM 74 CD1 LEU 128 9.089 6.744-7.128 1.00 0.00 ATOM 75 1HD1 LEU 128 8.176 7.243-6.838 1.00 0.00 ATOM 76 2HD1 LEU 128 8.893 6. 092-7.967 1.00 0.00 ATOM 77 3HD1 LEU 128 9.827 7.480-7.411 1.00 0.00 ATOM 78 CD2 LEU 128 10.832 5.123-6.392 1.00 0.00 ATOM 79 1HD2 LEU 128 11.260 5.569-7.278 1.00 0.00 ATOM 80 2HD2 LEU 128 10.538 4.107-6.608 1.00 0.00 ATOM 81 3HD2 LEU 128 11.565 5.125-5.598 1.00 0.00 ATOM 82 QQD LEU 128 10.043 5.936-6.950 1.00 0.00 ATOM 83 C LEU 128 9.886 5.553-2.608 1.00 0.00 ATOM 84 O LEU 128 9.923 5.686-1.384 1.00 0.00 ATOM 85 N VAL 129 10.436 4.533-3.251 1.00 0.00 ATOM 86 H VAL 129 10.347 4.499-4.225 1.00 0.00

ATOM 87 CA VAL 129 11.149 3.448-2.583 1.00 0.00 ATOM 88 HA VAL 129 10.504 3.036-1.826 1.00 0.00 ATOM 89 CB VAL 129 11.466 2.338-3.612 1.00 0.00 ATOM 90 HB VAL 129 12.131 2.754-4.356 1.00 0.00 ATOM 91 QG1 VAL 129 12.341 0.875-2.818 1.00 0.00 ATOM 92 QG2 VAL 129 9.895 1.783-4.483 1.00 0.00 ATOM 93 CG1 VAL 129 12.172 1.155-2.970 1.00 0.00 ATOM 94 1HG1 VAL 129 11.755 0.236-3.352 1.00 0.00 ATOM 95 2HG1 VAL 129 12.041 1.193-1.898 1.00 0.00 ATOM 96 3HG1 VAL 129 13.227 1.196-3.203 1.00 0.00 ATOM 97 CG2 VAL 129 10.196 1. 889-4.316 1.00 0.00 ATOM 98 1HG2 VAL 129 10.201 2.252-5.333 1.00 0.00 ATOM 99 2HG2 VAL 129 9.336 2.287-3.795 1.00 0.00 ATOM 100 3HG2 VAL 129 10.148 0.811-4.319 1.00 0.00 ATOM 101 QQG VAL 129 11.118 1.329-3.650 1.00 0.00 ATOM 102 C VAL 129 12.457 3.913-1.936 1.00 0.00 ATOM 103 O VAL 129 13.270 4.581-2.575 1.00 0.00 ATOM 104 N PRO 130 12.679 3.550-0.651 1.00 0.00 ATOM 105 CD PRO 130 11.772 2.765 0.187 1.00 0.00 ATOM 106 CA PRO 130 13.893 3.904 0.085 1.00 0.00 ATOM 107 HA PRO 130 14.141 4.948-0.047 1.00 0.00 ATOM 108 CB PRO 130 13.527 3.641 1.558 1.00 0.00 ATOM 109 1HB PRO 130 13.714 4.532 2.139 1.00 0.00 ATOM 110 2HB PRO 130 14.130 2.828 1.936 1.00 0.00 ATOM 111 QB PRO 130 13.922 3.680 2.037 1.00 0.00 ATOM 112 CG PRO 130 12.073 3.286 1.561 1.00 0.00 ATOM 113 1HG PRO 130 11.481 4.166 1.766 1.00 0.00 ATOM 114 2HG PRO 130 11.882 2.523 2.301 1.00 0.00 ATOM 115 QG PRO 130 11.681 3.344 2.033 1.00 0.00 ATOM 116 1HD PRO 130 10.742 2.950-0.072 1.00 0.00 ATOM 117 2HD PRO 130 12.000 1.710 0.121 1.00 0.00 ATOM 118 QD PRO 130 11.371 2.330 0.024 1.00 0.00 ATOM 119 C PRO 130 15.095 3.043-0.327 1.00 0.00 ATOM 120 O PRO 130 15.135 2.495-1.427 1.00 0.00 ATOM 121 N ASP 131 16.078 2.953 0.562 1.00 0.00 ATOM 122 H ASP 131 15.993 3.430 1.410 1.00 0.00 ATOM 123 CA ASP 131 17.301 2.197 0.304 1.00 0.00 ATOM 124 HA ASP 131 17.525 2.294-0.747 1.00 0.00 ATOM 125 CB ASP 131 18.447 2.839 1.104 1.00 0.00 ATOM 126 1HB ASP 131 18.025 3.504 1.843 1.00 0.00 ATOM 127 2HB ASP 131 19.062 3.411 0.432 1.00 0.00 ATOM 128 QB ASP 131 18.543 3.457 1.137 1.00 0.00 ATOM 129 CG ASP 131 19.330 1.839 1.818 1.00 0.00 ATOM 130 OD1 ASP 131 19.056 1.541 2.999 1.00 0.00 ATOM 131 OD2 ASP 131 20.299 1.348 1.205 1.00 0.00 ATOM 132 C ASP 131 17.173 0.699 0.632 1.00 0.00 ATOM 133 O ASP 131 17.804-0. 137-0.017 1.00 0.00 ATOM 134 N LYS+ 132 16.393 0.351 1.653 1.00 0.00 ATOM 135 H LYS+ 132 15.929 1.043 2.163 1.00 0.00 ATOM 136 CA LYS+ 132 16.261-1.057 2.039 1.00 0.00 ATOM 137 HA LYS+ 132 17.043-1.597 1.527 1.00 0.00 ATOM 138 CB LYS+ 132 16.472-1.222 3.547 1.00 0.00 ATOM 139 1HB LYS+ 132 15.980-2.127 3.870 1.00 0.00 ATOM 140 2HB LYS+ 132 16.027-0.379 4.056 1.00 0.00 ATOM 141 QB LYS+ 132 16.003-1.253 3.963 1.00 0.00 ATOM 142 CG LYS+ 132 17.939-1.304 3.948 1.00 0.00 ATOM 143 1HG LYS+ 132 18.002-1.437 5.019 1.00 0.00 ATOM 144 2HG LYS+ 132 18.428-0.380 3.669 1.00 0.00 ATOM 145 QG LYS+ 132 18.215-0.909 4.344 1.00 0.00 ATOM 146 CD LYS+ 132 18.648-2.465 3.260 1.00 0.00 ATOM 147 1HD LYS+ 132 17.909-3.090 2.778 1.00 0.00 ATOM 148 2HD LYS+ 132 19.178-3.043 4.004 1.00 0.00 ATOM 149 QD LYS+ 132 18.543-3.067 3.391 1.00 0.00 ATOM 150 CE LYS+ 132 19.642-1.977 2.213 1.00 0.00 ATOM 151 1HE LYS+ 132 19.093-1.668 1.332 1.00 0.00 ATOM 152 2HE LYS+ 132 20.304-2.790 1.955 1.00 0.00 ATOM 153 QE LYS+ 132 19.698-2.229 1.643 1.00 0.00 ATOM 154 NZ LYS+ 132 20.452-0.830 2.704 1.00 0.00 ATOM 155 1HZ LYS+ 132 20.100-0.506 3.626 1.00 0.00 ATOM 156 2HZ LYS+ 132 20.380-0.023 2.028 1.00 0.00 ATOM 157 3HZ LYS+ 132 21.449-1.097 2.793 1.00 0.00 ATOM 158 QZ LYS+ 132 20.643-0.542 2.815 1.00 0.00

ATOM 159 C LYS+ 132 14.923-1.668 1.632 1.00 0.00 ATOM 160 O LYS+ 132 14.881-2. 699 0.962 1.00 0.00 ATOM 161 N CYS 133 13.832-1.051 2.050 1.00 0.00 ATOM 162 H CYS 133 13.918-0.246 2.590 1.00 0.00 ATOM 163 CA CYS 133 12.505-1.560 1.731 1.00 0.00 ATOM 164 HA CYS 133 12.584-2.624 1.568 1.00 0.00 ATOM 165 CB CYS 133 11.535-1.296 2.885 1.00 0.00 ATOM 166 1HB CYS 133 10.547-1.137 2.475 1.00 0.00 ATOM 167 2HB CYS 133 11.844-0.400 3.401 1.00 0.00 ATOM 168 QB CYS 133 11.195-0.769 2.938 1.00 0.00 ATOM 169 SG CYS 133 11.408-2.630 4.123 1.00 0.00 ATOM 170 C CYS 133 11.966-0.900 0.474 1.00 0. 00 ATOM 171 O CYS 133 12.579 0.008-0.068 1.00 0.00 ATOM 172 N LYS+ 134 10.807-1.356 0.033 1.00 0.00 ATOM 173 H LYS+ 134 10.364-2.081 0.523 1.00 0.00 ATOM 174 CA LYS+ 134 10.154-0.811-1.144 1.00 0.00 ATOM 175 HA LYS+ 134 10.840-0.130-1.626 1.00 0. 00 ATOM 176 CB LYS+ 134 9.781-1.937-2.114 1.00 0.00 ATOM 177 1HB LYS+ 134 8.916-2.456-1.723 1.00 0.00 ATOM 178 2HB LYS+ 134 10.607-2.630-2.174 1.00 0.00 ATOM 179 QB LYS+ 134 9.761-2.543-1.949 1.00 0.00 ATOM 180 CG LYS+ 134 9.455-1.463-3.520 1.00 0.00 ATOM 181 1HG LYS+ 134 10.055-0.590-3.741 1.00 0.00 ATOM 182 2HG LYS+ 134 8.409-1.203-3.571 1.00 0.00 ATOM 183 QG LYS+ 134 9.232-0.897-3.656 1.00 0.00 ATOM 184 CD LYS+ 134 9.749-2.539-4.555 1.00 0.00 ATOM 185 1HD LYS+ 134 10.169-3.401-4.056 1.00 0.00 ATOM 186 2HD LYS+ 134 10.465-2.152-5.267 1.00 0.00 ATOM 187 QD LYS+ 134 10.317-2.777-4.662 1.00 0.00 ATOM 188 CE LYS+ 134 8.492-2.960-5.302 1.00 0.00 ATOM 189 1HE LYS+ 134 8.718-3.835-5.894 1.00 0.00 ATOM 190 2HE LYS+ 134 8.191-2.153-5.955 1.00 0.00 ATOM 191 QE LYS+ 134 8.454-2.994-5.925 1.00 0.00 ATOM 192 NZ LYS+ 134 7.368-3.277-4.374 1.00 0.00 ATOM 193 1HZ LYS+ 134 7.737-3.650-3.474 1.00 0.00 ATOM 194 2HZ LYS+ 134 6.742-3.990-4.798 1.00 0.00 ATOM 195 3HZ LYS+ 134 6.810-2.419-4.177 1.00 0.00 ATOM 196 QZ LYS+ 134 7.096-3.353-4.150 1.00 0.00 ATOM 197 C LYS+ 134 8.909-0. 053-0.715 1.00 0. 00 ATOM 198 O LYS+ 134 7.931-0.661-0.291 1.00 0.00 ATOM 199 N PHE 135 8.951 1.266-0.808 1.00 0.00 ATOM 200 H PHE 135 9.763 1.697-1.146 1.00 0.00 ATOM 201 CA PHE 135 7.819 2.091-0.408 1.00 0.00 ATOM 202 HA PHE 135 7.243 1.536 0.318 1.00 0.00 ATOM 203 CB PHE 135 8.306 3.396 0.230 1.00 0.00 ATOM 204 1HB PHE 135 8.786 3.999-0.529 1.00 0. 00 ATOM 205 2HB PHE 135 9.023 3.163 1.002 1.. 00 0.00 ATOM 206 QB PHE 135 8.904 3.581 0.236 1.00 0.00 ATOM 207 QD PHE 135 7.095 4.313 0.922 1.00 0. 00 ATOM 208 QE PHE 135 5.318 5.673 1.947 1.00 0.00 ATOM 209 QR PHE 135 5.850 5.265 1.640 1.00 0.00 ATOM 210 CG PHE 135 7.215 4.221 0.852 1.00 0.00 ATOM 211 CD1 PHE 135 6.196 3.624 1.576 1.00 0.00 ATOM 212 1HD PHE 135 6.185 2.549 1.690 1.00 0.00 ATOM 213 CE1 PHE 135 5.198 4.384 2.152 1.00 0.00 ATOM 214 1HE PHE 135 4.408 3.905 2.715 1.00 0.00 ATOM 215 CZ PHE 135 5.209 5.757 2.010 1.00 0. 00 ATOM 216 HZ PHE 135 4.427 6.354 2.461 1.00 0.00 ATOM 217 CE2 PHE 135 6.218 6.366 1.291 1.00 0. 00 ATOM 218 2HE PHE 135 6.229 7.441 1.179 1.00 0.00 ATOM 219 CD2 PHE 135 7.215 5.600 0.717 1.00 0.00 ATOM 220 2HD PHE 135 8.005 6.078 0.155 1.00 0.00 ATOM 221 C PHE 135 6.937 2.396-1.605 1.00 0.00 ATOM 222 O PHE 135 7. 401 2.932-2. 612 1. 00 0. 00 ATOM 223 N LEU 136 5.669 2.041-1.493 1.00 0.00 ATOM 224 H LEU 136 5.362 1.608-0.664 1.00 0.00 ATOM 225 CA LEU 136 4.722 2.265-2.564 1.00 0.00 ATOM 226 HA LEU 136 5.232 2.807-3.346 1.00 0.00 ATOM 227 CB LEU 136 4.223 0.931-3.128 1.00 0.00 ATOM 228 1HB LEU 136 3. 522 1.142-3.922 1.00 0.00 ATOM 229 2HB LEU 136 3.699 0. 407-2.341 1. 00 0.00 ATOM 230 QB LEU 136 3.610 0.774-3.132 1. 00 0.00

ATOM 231 CG LEU 136 5.312 0.008-3.682 1.00 0.00 ATOM 232 HG LEU 136 6.178 0.599-3.943 1.00 0.00 ATOM 233 QD1 LEU 136 5.830-1.246-2.383 1.00 0.00 ATOM 234 QD2 LEU 136 4.708-0.866-5.233 1.00 0.00 ATOM 235 CD1 LEU 136 5.732-1.006-2.633 1.00 0.00 ATOM 236 lHDl LEU 136 5.296-1.967-2.865 1.00 0.00 ATOM 237 2HD1 LEU 136 5.386-0.681-1.662 1.00 0.00 ATOM 238 3HD1 LEU 136 6.808-1.089-2.621 1.00 0.00 ATOM 239 CD2 LEU 136 4.824-0.699-4.936 1.00 0.00 ATOM 240 1HD2 LEU 136 5.635-0.778-5.644 1.00 0.00 ATOM 241 2HD2 LEU 136 4.016-0.132-5.376 1.00 0.00 ATOM 242 3HD2 LEU 136 4.473-1.686-4.679 1.00 0.00 ATOM 243 QQD LEU 136 5.269-1.056-3.808 1.00 0.00 ATOM 244 C LEU 136 3.544 3.097-2.080 1.00 0.00 ATOM 245 O LEU 136 2.474 2.563-1.798 1.00 0.00 ATOM 246 N HIS+ 137 3.736 4.408-2.014 1.00 0.00 ATOM 247 H HIS+ 137 4.605 4.779-2.273 1.00 0.00 ATOM 248 CA HIS+ 137 2.671 5.308-1.599 1.00 0.00 ATOM 249 HA HIS+ 137 1.979 4.750-0.980 1.00 0.00 ATOM 250 CB HIS+ 137 3.231 6.509-0.806 1.00 0.00 ATOM 251 1HB HIS+ 137 4.078 6.916-1.340 1.00 0.00 ATOM 252 2HB HIS+ 137 3.560 6.166 0.164 1.00 0.00 ATOM 253 QB HIS+ 137 3.819 6.541-0.588 1.00 0.00 ATOM 254 CG HIS+ 137 2.244 7.631-0.585 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.632 7.879 0.626 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.761 8.568-1.440 1.00 0.00 ATOM 257 1HD HIS+ 137 1.779 7.376 1.470 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.817 8.913 0.502 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.874 9.351-0.742 1.00 0.00 ATOM 260 2HD HIS+ 137 2.024 8.677-2.484 1.00 0.00 ATOM 261 1HE HIS+ 137 0.204 9.329 1.289 1.00 0.00 ATOM 262 2HE HIS+ 137 0.203 9.953-1.160 1.00 0.00 ATOM 263 C HIS+ 137 1.959 5.788-2.852 1.00 0.00 ATOM 264 O HIS+ 137 2.522 6.548-3.641 1.00 0.00 ATOM 265 N GLN 138 0.741 5.317-3.062 1.00 0.00 ATOM 266 H GLN 138 0.345 4.690-2.415 1.00 0.00 ATOM 267 CA GLN 138-0.009 5. 693-4.250 1.00 0.00 ATOM 268 HA GLN 138 0.416 6.609-4.632 1.00 0.00 ATOM 269 CB GLN 138 0. 104 4.603-5.325 1.00 0.00 ATOM 270 1HB GLN 138 0.027 5.068-6.297 1.00 0.00 ATOM 271 2HB GLN 138-0.715 3.911-5.202 1.00 0.00 ATOM 272 QB GLN 138-0.344 4.489-5.750 1.00 0.00 ATOM 273 CG GLN 138 1.407 3.812-5.278 1.00 0.00 ATOM 274 1HG GLN 138 1.174 2.765-5.152 1.00 0.00 ATOM 275 2HG GLN 138 1.987 4.153-4.433 1.00 0.00 ATOM 276 QG GLN 138 1.580 3.459-4.793 1.00 0.00 ATOM 277 CD GLN 138 2.240 3.977-6.533 1.00 0.00 ATOM 278 OE1 GLN 138 1.766 3.706-7.636 1.00 0.00 ATOM 279 NE2 GLN 138 3.484 4.423-6.373 1.00 0.00 ATOM 280 1HE2 GLN 138 3.796 4.621-5.463 1.00 0.00 ATOM 281 2HE2 GLN 138 4.044 4.535-7.171 1.00 0.00 ATOM 282 QE2 GLN 138 3.920 4.578-6.317 1.00 0.00 ATOM 283 C GLN 138-1.476 5.930-3.923 1.00 0.00 ATOM 284 O GLN 138-2.119 5.108-3.266 1.00 0.00 ATOM 285 N GLU 139-2.001 7.046-4.401 1.00 0.00 ATOM 286 H GLU 139-1.439 7.652-4.927 1.00 0.00 ATOM 287 CA GLU 139-3.395 7.394-4.181 1.00 0.00 ATOM 288 HA GLU 139-3.729 6. 883-3.289 1.00 0.00 ATOM 289 CB GLU 139-3.539 8.907-3.981 1.00 0.00 ATOM 290 1HB GLU 139-4.053 9.090-3.049 1.00 0.00 ATOM 291 2HB GLU 139-4.128 9.310-4.792 1.00 0.00 ATOM 292 QB GLU 139-4.091 9.200-3.921 1.00 0.00 ATOM 293 CG GLU 139-2.210 9.652-3.944 1.00 0.00 ATOM 294 1HG GLU 139-2.142 10.286-4.816 1.00 0.00 ATOM 295 2HG GLU 139-1.406 8.933-3.958 1.00 0.00 ATOM 296 QG GLU 139-1.774 9.609-4.387 1.00 0.00 ATOM 297 CD GLU 139-2.061 10.513-2.709 1.00 0.00 ATOM 298 OE1 GLU 139-0.928 10.625-2.198 1.00 0.00 ATOM 299 OE2 GLU 139-3.077 11. 067-2. 249 1.00 0.00 ATOM 300 C GLU 139-4.242 6.934-5.366 1.00 0.00 ATOM 301 O GLU 139-4.234 7.556-6.427 1.00 0.00 ATOM 302 N ARG+ 140-4.968 5.841-5.180 1.00 0.00

ATOM 303 H ARG+ 140-4.936 5.387-4.310 1.00 0.00 ATOM 304 CA ARG+ 140-5.820 5.297-6.230 1.00 0.00 ATOM 305 HA ARG+ 140-5.460 5.663-7.180 1.00 0.00 ATOM 306 CB ARG+ 140-5.762 3.766-6.223 1.00 0.00 ATOM 307 1HB ARG+ 140-6.490 3.397-5.513 1.00 0.00 ATOM 308 2HB ARG+ 140-4.777 3.454-5.910 1.00 0.00 ATOM 309 QB ARG+ 140-5. 634 3.425-5.712 1.00 0.00 ATOM 310 CG ARG+ 140-6. 055 3.137-7.574 1.00 0.00 ATOM 311 1HG ARG+ 140-6.661 3.823-8. 155 1.00 0.00 ATOM 312 2HG ARG+ 140-6. 598 2.216-7.423 1.00 0.00 ATOM 313 QG ARG+ 140-6.630 3.019-7.789 1.00 0.00 ATOM 314 CD ARG+ 140-4.777 2.841-8.338 1.00 0.00 ATOM 315 1HD ARG+ 140-4.197 3.749-8.402 1.00 0.00 ATOM 316 2HD ARG+ 140-5.039 2.511-9.334 1.00 0.00 ATOM 317 QD ARG+ 140-4.618 3.130-8.868 1.00 0.00 ATOM 318 NE ARG+ 140-3.976 1.803-7.685 1.00 0.00 ATOM 319 HE ARG+ 140-4. 459 1. 018-7.334 1.00 0.00 ATOM 320 CZ ARG+ 140-2.648 1. 865-7.556 1.00 0.00 ATOM 321 NH1 ARG+ 140-1.986 2.930-8. 000 1.00 0.00 ATOM 322 1HH1 ARG+ 140-2.485 3.686-8.430 1.00 0.00 ATOM 323 2HH1 ARG+ 140-0.990 2.984-7.906 1.00 0.00 ATOM 324 QH1 ARG+ 140-1.738 3.335-8.168 1.00 0.00 ATOM 325 NH2 ARG+ 140-1.986 0.868-6.976 1.00 0.00 ATOM 326 1HH2 ARG+ 140-2.481 0. 067-6. 634 1.00 0.00 ATOM 327 2HH2 ARG+ 140-0.989 0.912-6.883 1.00 0.00 ATOM 328 QH2 ARG+ 140-1.735 0.489-6.759 1.00 0.00 ATOM 329 C ARG+ 140-7.257 5.759-6.032 1.00 0.00 ATOM 330 O ARG+ 140-8.072 5.037-5.460 1.00 0.00 ATOM 331 N MET 141-7.564 6.962-6.505 1.00 0.00 ATOM 332 H MET 141-6.869 7.487-6.955 1.00 0.00 ATOM 333 CA MET 141-8.910 7.525-6.374 1.00 0.00 ATOM 334 HA MET 141-9.242 7.347-5.363 1.00 0.00 ATOM 335 CB MET 141-8.869 9.036-6.626 1.00 0.00 ATOM 336 1HB MET 141-8.959 9.211-7.689 1.00 0.00 ATOM 337 2HB MET 141-7.920 9.422-6.286 1.00 0.00 ATOM 338 QB MET 141-8.440 9.316-6.988 1.00 0.00 ATOM 339 CG MET 141-9.976 9.803-5.923 1.00 0.00 ATOM 340 1HG MET 141-10.223 9.289-5.007 1.00 0.00 ATOM 341 2HG MET 141-10.843 9.825-6.568 1.00 0.00 ATOM 342 QG MET 141-10.533 9.557-5.788 1.00 0.00 ATOM 343 SD MET 141-9.511 11. 499-5.527 1.00 0.00 ATOM 344 QE MET 141-9.871 12.473-7.413 1.00 0.00 ATOM 345 CE MET 141-9. 811 12.310-7.096 1.00 0. 00 ATOM 346 1HE MET 141-10.871 12.470-7.223 1.00 0.00 ATOM 347 2HE MET 141-9.442 11. 689-7.900 1.00 0.00 ATOM 348 3HE MET 141-9.299 13.261-7.114 1.00 0.00 ATOM 349 C MET 141-9.898 6.862-7.339 1.00 0.00 ATOM 350 O MET 141-10.833 7.503-7.824 1.00 0.00 ATOM 351 N ASP 142-9.681 5.584-7.609 1.00 0.00 ATOM 352 H ASP 142-8.919 5.136-7.192 1.00 0.00 ATOM 353 CA ASP 142-10.524 4.825-8.509 1.00 0.00 ATOM 354 HA ASP 142-11.202 5.509-8.995 1.00 0.00 ATOM 355 CB ASP 142-9.660 4.136-9.569 1.00 0.00 ATOM 356 1HB ASP 142-10.285 3.858-10.395 1.00 0.00 ATOM 357 2HB ASP 142-9.220 3.248-9.144 1.00 0.00 ATOM 358 QB ASP 142-9.753 3.553-9.770 1.00 0.00 ATOM 359 CG ASP 142-8.544 5.019-10.089 1.00 0.00 ATOM 360 OD1 ASP 142-8.735 5.657-11.142 1.00 0.00 ATOM 361 OD2 ASP 142-7.474 5.067-9.444 1.00 0.00 ATOM 362 C ASP 142-11.323 3.774-7.752 1.00 0.00 ATOM 363 O ASP 142-12.512 3.576-8.003 1.00 0.00 ATOM 364 N VAL 143-10.658 3.084-6.835 1.00 0.00 ATOM 365 H VAL 143-9.709 3.275-6.687 1.00 0.00 ATOM 366 CA VAL 143-11.304 2.034-6.059 1.00 0.00 ATOM 367 HA VAL 143-12. 260 1.830-6.519 1.00 0.00 ATOM 368 CB VAL 143-10.469 0.734-6.080 1.00 0.00 ATOM 369 HB VAL 143-9.821 0.735-5.215 1.00 0.00 ATOM 370 QG1 VAL 143-11.576-0.783-5.979 1. 00 0.00 ATOM 371 QG2 VAL 143-9.393 0.646-7.620 1.00 0.00 ATOM 372 CG1 VAL 143-11.366-0.491-5. 997 1.00 0. 00 ATOM 373 1HG1 VAL 143-12.235-0.346-6.621 1.00 0.00 ATOM 374 2HG1 VAL 143-11.675-0.644-4.974 1.00 0.00

ATOM 375 3HG1 VAL 143-10.817-1.357-6.340 1.00 0.00 ATOM 376 CG2 VAL 143-9. 598 0.663-7.325 1.00 0.00 ATOM 377 1HG2 VAL 143-9.824 1.499-7.971 1.00 0.00 ATOM 378 2HG2 VAL 143-9.796-0.260-7.850 1.00 0.00 ATOM 379 3HG2 VAL 143-8.557 0.699-7.039 1.00 0.00 ATOM 380 QQG VAL 143-10.484-0.069-6.800 1.00 0.00 ATOM 381 C VAL 143-11.539 2.481-4.614 1.00 0.00 ATOM 382 O VAL 143-10.838 3.349-4.102 1.00 0.00 ATOM 383 N CYS 144-12.533 1.882-3. 964 1.00 0.00 ATOM 384 H CYS 144-13.057 1.196-4.427 1.00 0.00 ATOM 385 CA CYS 144-12.869 2.218-2.581 1.00 0.00 ATOM 386 HA CYS 144-12.022 2.724-2.136 1.00 0.00 ATOM 387 CB CYS 144-14.086 3.143-2. 546 1.00 0.00 ATOM 388 1HB CYS 144-14.608 2.997-1.612 1.00 0.00 ATOM 389 2HB CYS 144-14.744 2.887-3.362 1.00 0.00 ATOM 390 QB CYS 144-14.676 2.942-2.487 1.00 0.00 ATOM 391 SG CYS 144-13.691 4.914-2.692 1.00 0.00 ATOM 392 C CYS 144-13.173 0.960-1.784 1.00 0.00 ATOM 393 O CYS 144-14.307 0.478-1.789 1.00 0.00 ATOM 394 N GLU 145-12.167 0.425-1.106 1.00 0.00 ATOM 395 H GLU 145-11.283 0.846-1.141 1.00 0.00 ATOM 396 CA GLU 145-12.347-0.787-0.325 1.00 0.00 ATOM 397 HA GLU 145-13.388-1.059-0.378 1.00 0.00 ATOM 398 CB GLU 145-11.523-1.919-0. 929 1.00 0.00 ATOM 399 1HB GLU 145-11. 264-2.617-0.149 1.00 0.00 ATOM 400 2HB GLU 145-10.615-1.510-1.347 1.00 0.00 ATOM 401 QB GLU 145-10.940-2.064-0.748 1.00 0. 00 ATOM 402 CG GLU 145-12.266-2.676-2.018 1.00 0.00 ATOM 403 1HG GLU 145-11.794-3.637-2.162 1.00 0.00 ATOM 404 2HG GLU 145-12.217-2.108-2. 935 1.00 0.00 ATOM 405 QG GLU 145-12.006-2.873-2.549 1.00 0.00 ATOM 406 CD GLU 145-13.718-2.896-1.660 1.00 0.00 ATOM 407 OE1 GLU 145-13.985-3.344-0.523 1.00 0.00 ATOM 408 OE2 GLU 145-14.592-2.587-2.489 1.00 0.00 ATOM 409 C GLU 145-11.973-0.592 1.135 1.00 0.00 ATOM 410 O GLU 145-11.544 0.487 1.545 1.00 0.00 ATOM 411 N THR 146-12.153-1.654 1.908 1.00 0.00 ATOM 412 H THR 146-12.504-2.476 1.506 1.00 0.00 ATOM 413 CA THR 146-11.857-1.647 3.331 1.00 0.00 ATOM 414 HA THR 146-12.260-0.739 3.756 1.00 0.00 ATOM 415 CB THR 146-12.532-2.855 3.986 1.00 0.00 ATOM 416 HB THR 146-11.841-3.686 3.975 1.00 0.00 ATOM 417 QG2 THR 146-13.048-2.562 5.764 1.00 0.00 ATOM 418 OG1 THR 146-13.689-3.231 3.256 1.00 0.00 ATOM 419 1HG THR 146-14.440-3.294 3.854 1.00 0.00 ATOM 420 CG2 THR 146-12.948-2.619 5.421 1.00 0.00 ATOM 421 1HG2 THR 146-13.313-1.606 5.531 1.00 0.00 ATOM 422 2HG2 THR 146-12.099-2.765 6.072 1.00 0.00 ATOM 423 3HG2 THR 146-13.730-3.313 5.691 1.00 0.00 ATOM 424 C THR 146-10.349-1.689 3.569 1. 00 0.00 ATOM 425 O THR 146-9.575-1.995 2.657 1.00 0.00 ATOM 426 N HIS+ 147-9.941-1.389 4.800 1.00 0.00 ATOM 427 H HIS+ 147-10.613-1.157 5.480 1.00 0.00 ATOM 428 CA HIS+ 147-8. 527-1. 395 5.173 1.00 0.00 ATOM 429 HA HIS+ 147-8.023-0.647 4.581 1.00 0.00 ATOM 430 CB HIS+ 147-8.374-1.045 6.655 1.00 0.00 ATOM 431 1HB HIS+ 147-8.208-1.953 7.216 1.00 0.00 ATOM 432 2HB HIS+ 147-9.284-0.577 7.003 1.00 0.00 ATOM 433 QB HIS+ 147-8.746-1.265 7.109 1.00 0.00 ATOM 434 CG HIS+ 147-7.238-0.110 6.943 1.00 0.00 ATOM 435 ND1 HIS+ 147-7.407 1.246 7.121 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.912-0.345 7.094 1.00 0.00 ATOM 437 1HD HIS+ 147-8.263 1.732 7.066 1.00 0.00 ATOM 438 CE1 HIS+ 147-6.235 1.806 7.369 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.312 0.862 7.359 1.00 0.00 ATOM 440 2HD HIS+ 147-5.414-1.304 7. 003 1.00 0.00 ATOM 441 1HE HIS+ 147-6.063 2.858 7.550 1.00 0.00 ATOM 442 2HE HIS+ 147-4.371 0.989 7.611 1.00 0.00 ATOM 443 C HIS+ 147-7.888-2.756 4.899 1.00 0.00 ATOM 444 O HIS+ 147-6.707-2.843 4.578 1.00 0.00 ATOM 445 N LEU 148-8.676-3.815 5.029 1.00 0.00 ATOM 446 H LEU 148-9.612-3.685 5.287 1.00 0.00

ATOM 447 CA LEU 148-8.181-5.167 4.798 1.00 0.00 ATOM 448 HA LEU 148-7.241-5.268 5.319 1.00 0.00 ATOM 449 CB LEU 148-9.168-6.197 5.353 1.00 0.00 ATOM 450 1HB LEU 148-9.881-6.436 4.578 1.00 0.00 ATOM 451 2HB LEU 148-9.699-5.748 6.181 1.00 0.00 ATOM 452 QB LEU 148-9.790-6.092 5.379 1.00 0.00 ATOM 453 CG LEU 148-8. 536-7.502 5.839 1.00 0.00 ATOM 454 HG LEU 148-7.467-7.369 5.919 1.00 0.00 ATOM 455 QD1 LEU 148-9. 193-7.963 7.537 1.00 0.00 ATOM 456 QD2 LEU 148-8. 860-8.891 4.612 1.00 0.00 ATOM 457 CD1 LEU 148-9.068-7.874 7.212 1.00 0.00 ATOM 458 1HD1 LEU 148-10.059-8.290 7.113 1.00 0.00 ATOM 459 2HD1 LEU 148-9.106-6.993 7.835 1.00 0.00 ATOM 460 3HD1 LEU 148-8.414-8.606 7.663 1.00 0.00 ATOM 461 CD2 LEU 148-8.799-8.624 4.847 1.00 0.00 ATOM 462 1HD2 LEU 148-8.572-9.573 5.310 1.00 0.00 ATOM 463 2HD2 LEU 148-8.172-8.490 3.977 1.00 0.00 ATOM 464 3HD2 LEU 148-9.836-8.608 4.549 1.00 0.00 ATOM 465 QQD LEU 148-9.027-8.427 6. 074 1.00 0.00 ATOM 466 C LEU 148-7.949-5.427 3.314 1.00 0.00 ATOM 467 O LEU 148-6.980-6.083 2.941 1.00 0.00 ATOM 468 N HIS+ 149-8.844-4.920 2.472 1.00 0.00 ATOM 469 H HIS+ 149-9.599-4.408 2.826 1.00 0.00 ATOM 470 CA HIS+ 149-8.726-5.119 1.032 1.00 0.00 ATOM 471 HA HIS+ 149-8.671-6.185 0.865 1.00 0.00 ATOM 472 CB HIS+ 149-9.957-4.583 0.304 1.00 0.00 ATOM 473 1HB HIS+ 149-9.644-4.023-0.566 1.00 0.00 ATOM 474 2HB HIS+ 149-10.509-3.931 0.966 1.00 0.00 ATOM 475 QB HIS+ 149-10.077-3.977 0.200 1.00 0.00 ATOM 476 CG HIS+ 149-10.878-5.675-0.152 1.00 0.00 ATOM 477 ND1 HIS+ 149-12. 217-5.479-0.422 1.00 0.00 ATOM 478 CD2 HIS+ 149-10.642-6.990-0.381 1.00 0.00 ATOM 479 1HD HIS+ 149-12.702-4.616-0.366 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.762-6.624-0.794 1.00 0.00 ATOM 481 NE2 HIS+ 149-11.828-7.556-0.778 1.00 0.00 ATOM 482 2HD HIS+ 149-9.693-7.499-0.273 1.00 0.00 ATOM 483 1HE HIS+ 149-13.797-6.769-1.070 1.00 0.00 ATOM 484 2HE HIS+ 149-11.935-8.465-1.128 1.00 0.00 ATOM 485 C HIS+ 149-7.448-4.495 0.489 1.00 0.00 ATOM 486 O HIS+ 149-6. 679-5.169-0.191 1.00 0.00 ATOM 487 N TRP 150-7.205-3.226 0.806 1.00 0.00 ATOM 488 H TRP 150-7. 848-2.736 1.366 1.00 0.00 ATOM 489 CA TRP 150-5.984-2.554 0.352 1.00 0.00 ATOM 490 HA TRP 150-5.932-2.633-0.724 1.00 0.00 ATOM 491 CB TRP 150-5.970-1.084 0.761 1.00 0.00 ATOM 492 1HB TRP 150-5.000-0.668 0.528 1.00 0.00 ATOM 493 2HB TRP 150-6.133-1.016 1.825 1.00 0.00 ATOM 494 QB TRP 150-5. 567-0.842 1.176 1.00 0.00 ATOM 495 CG TRP 150-7. 005-0.238 0.089 1.00 0.00 ATOM 496 CD1 TRP 150-7. 473 0.963 0.531 1.00 0.00 ATOM 497 CD2 TRP 150-7.693-0.510-1.137 1.00 0.00 ATOM 498 CE3 TRP 150-7.664-1.558-2.060 1.00 0.00 ATOM 499 CE2 TRP 150-8.561 0.571-1.369 1.00 0.00 ATOM 500 NE1 TRP 150-8. 406 1.453-0.339 1.00 0.00 ATOM 501 HD TRP 150-7.144 1.446 1.440 1.00 0.00 ATOM 502 3HE TRP 150-7. 012-2.407-1.921 1.00 0.00 ATOM 503 CZ3 TRP 150-8.486-1.496-3.163 1.00 0.00 ATOM 504 CZ2 TRP 150-9. 387 0.633-2.480 1.00 0.00 ATOM 505 1HE TRP 150-8.887 2.303-0.238 1.00 0.00 ATOM 506 3HZ TRP 150-8. 480-2.298-3.884 1.00 0.00 ATOM 507 CH2 TRP 150-9.337-0.407-3.363 1.00 0.00 ATOM 508 2HZ TRP 150-10. 054 1.468-2.652 1.00 0.00 ATOM 509 HH TRP 150-9. 965-0.401-4.241 1.00 0.00 ATOM 510 C TRP 150-4. 768-3.240 0.932 1.00 0.00 ATOM 511 O TRP 150-3. 742-3.336 0.274 1.00 0.00 ATOM 512 N HIS+ 151-4.899-3.737 2.157 1.00 0.00 ATOM 513 H HIS+ 151-5.756-3.641 2.625 1.00 0.00 ATOM 514 CA HIS+ 151-3.808-4.446 2.807 1.00 0.00 ATOM 515 HA HIS+ 151-2.962-3.779 2.872 1.00 0.00 ATOM 516 CB HIS+ 151-4.230-4.891 4.220 1.00 0.00 ATOM 517 1HB HIS+ 151-5.096-5.533 4.135 1.00 0.00 ATOM 518 2HB HIS+ 151-4.498-4.017 4.794 1.00 0.00'

ATOM 519 QB HIS+ 151-4.797-4.775 4.464 1.00 0. 00 ATOM 520 CG HIS+ 151-3.178-5.639 4.994 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.847-5.336 6.297 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.400-6.696 4.651 1.00 0.00 ATOM 523 1HD HIS+ 151-3.238-4.615 6.837 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.914-6.173 6.719 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.627-7.007 5.740 1.00 0. 00 ATOM 526 2HD HIS+ 151-2. 388-7.195 3.689 1.00 0.00 ATOM 527 1HE HIS+ 151-1.456-6.168 7.698 1.00 0.00 ATOM 528 2HE HIS+ 151-1.055-7.799 5.824 1.00 0.00 ATOM 529 C HIS+ 151-3.434-5.654 1.961 1.00 0.00 ATOM 530 O HIS+ 151-2.261-5.894 1.693 1.00 0.00 ATOM 531 N THR 152-4.448-6.399 1.539 1.00 0.00 ATOM 532 H THR 152-5.362-6.143 1.785 1.00 0.00 ATOM 533 CA THR 152-4.240-7.577 0.714 1.00 0.00 ATOM 534 HA THR 152-3. 515-8.202 1.212 1.00 0.00 ATOM 535 CB THR 152-5.547-8.362 0.557 1.00 0.00 ATOM 536 HB THR 152-6. 160-7.876-0.189 1.00 0.00 ATOM 537 QG2 THR 152-5.288-10.138 0.016 1.00 0.00 ATOM 538 OG1 THR 152-6.270-8.396 1.778 1.00 0.00 ATOM 539 1HG THR 152-6.397-7.500 2.109 1.00 0.00 ATOM 540 CG2 THR 152-5.338-9.796 0.121 1.00 0.00 ATOM 541 1HG2 THR 152-5.370-10.444 0.984 1.00 0. 00 ATOM 542 2HG2 THR 152-4.376-9.890-0.364 1.00 0.00 ATOM 543 3HG2 THR 152-6.118-10. 080-0.571 1.00 0.00 ATOM 544 C THR 152-3.684-7.191-0.651 1.00 0.00 ATOM 545 O THR 152-2.703-7.764-1.092 1.00 0.00 ATOM 546 N VAL 153-4.298-6.209-1.312 1.00 0.00 ATOM 547 H VAL 153-5.079-5.764-0.908 1.00 0.00 ATOM 548 CA VAL 153-3.819-5.773-2.622 1.00 0.00 ATOM 549 HA VAL 153-3.868-6.617-3.288 1.00 0.00 ATOM 550 CB VAL 153-4.688-4.634-3.201 1.00 0.00 ATOM 551 HB VAL 153-4.601-3.776-2.550 1.00 0.00 ATOM 552 QG1 VAL 153-4.091-4.138-4.915 1.00 0.00 ATOM 553 QG2 VAL 153-6.498-5.147-3.263 1.00 0.00 ATOM 554 CG1 VAL 153-4.205-4.232-4.586 1.00 0.00 ATOM 555 1HG1 VAL 153-3.192-4.580-4.730 1.00 0.00 ATOM 556 2HG1 VAL 153-4.234-3.157-4.679 1.00 0.00 ATOM 557 3HG1 VAL 153-4.846-4.676-5.334 1.00 0.00 ATOM 558 CG2 VAL 153-6.151-5.049-3.251 1.00 0.00 ATOM 559 1HG2 VAL 153-6.723-4.290-3.764 1.00 0.00 ATOM 560 2HG2 VAL 153-6.527-5.165-2.245 1.00 0.00 ATOM 561 3HG2 VAL 153-6.242-5.986-3.780 1.00 0.00 ATOM 562 QQG VAL 153-5.294-4.643-4.089 1.00 0.00 ATOM 563 C VAL 153-2.370-5.322-2.529 1.00 0.00 ATOM 564 O VAL 153-1.529-5.737-3.322 1.00 0.00 ATOM 565 N ALA 154-2. 090-4.489-1.544 1.00 0.00 ATOM 566 H ALA 154-2. 816-4. 207-0.936 1. 00 0. 00 ATOM 567 CA ALA 154-0.743-3.988-1.317 1.00 0.00 ATOM 568 HA ALA 154-0.419-3.459-2.201 1.00 0.00 ATOM 569 QB ALA 154-0.755-2.789 0.126 1.00 0.00 ATOM 570 CB ALA 154-0.752-3.019-0.150 1.00 0.00 ATOM 571 1HB ALA 154-1.765-2.691 0.038 1.00 0.00 ATOM 572 2HB ALA 154-0.135-2.164-0.388 1.00 0.00 ATOM 573 3HB ALA 154-0.363-3.510 0.729 1.00 0.00 ATOM 574 C ALA 154 0.230-5.127-1.037 1.00 0.00 ATOM 575 O ALA 154 1. 282-5.232-1.674 1.00 0.00 ATOM 576 N LYS+ 155-0.128-5.971-0.075 1.00 0.00 ATOM 577 H LYS+ 155-0.981-5.826 0.393 1.00 0. 00 ATOM 578 CA LYS+ 155 0.706-7.103 0.306 1.00 0.00 ATOM 579 HA LYS+ 155 1.668-6.716 0.622 1.00 0. 00 ATOM 580 CB LYS+ 155 0.070-7.882 1.463 1.00 0. 00 ATOM 581 1HB LYS+ 155-0.824-8.371 1.098 1.00 0.00 ATOM 582 2HB LYS+ 155-0.203-7.187 2.242 1.00 0. 00 ATOM 583 QB LYS+ 155-0.514-7.779 1.670 1.00 0. 00 ATOM 584 CG LYS+ 155 0.980-8.944 2.067 1.00 0.00 ATOM 585 1HG LYS+ 155 1.622-8.479 2.802 1.00 0. 00 ATOM 586 2HG LYS+ 155 1.581-9.377 1.281 1.00 0. 00 ATOM 587 QG LYS+ 155 1.601-8.928 2.041 1.00 0.00 ATOM 588 CD LYS+ 155 0.175-10.050 2.738 1.00 0.00 ATOM 589 1HD LYS+ 155-0.868-9.933 2.476 1. 00 0. 00 ATOM 590 2HD LYS+ 155 0.290-9.964 3.808 1.00 0.00

ATOM 591 QD LYS+ 155-0.289-9.949 3.142 1.00 0.00 ATOM 592 CE LYS+ 155 0.641-11.436 2.303 1.00 0.00 ATOM 593 1HE LYS+ 155-0.092-12.163 2.624 1.00 0.00 ATOM 594 2HE LYS+ 155 1.587-11.650 2.778 1.00 0.00 ATOM 595 QE LYS+ 155 0.747-11.907 2.701 1.00 0.00 ATOM 596 NZ LYS+ 155 0.807-11.536 0.829 1.00 0.00 ATOM 597 1HZ LYS+ 155 1.677-11.047 0.522 1.00 0.00 ATOM 598 2HZ LYS+ 155-0.018-11.102 0.343 1.00 0.00 ATOM 599 3HZ LYS+ 155 0.861-12.532 0.537 1.00 0.00 ATOM 600 QZ LYS+ 155 0.840-11.561 0.467 1.00 0.00 ATOM 601 C LYS+ 155 0.927-8.029-0.872 1.00 0.00 ATOM 602 O LYS+ 155 2.057-8.406-1.142 1.00 0.00 ATOM 603 N GLU 156-0. 148-8.396-1.561 1.00 0.00 ATOM 604 H GLU 156-1. 037-8.069-1.289 1.00 0.00 ATOM 605 CA GLU 156-0. 046-9.290-2.703 1.00 0.00 ATOM 606 HA GLU 156 0.413-10.203-2.354 1.00 0.00 ATOM 607 CB GLU 156-1.430-9.627-3.258 1.00 0.00 ATOM 608 1HB GLU 156-1.311-10.126-4.210 1.00 0.00 ATOM 609 2HB GLU 156-1.977-8.710-3.408 1.00 0.00 ATOM 610 QB GLU 156-1.644-9.418-3.809 1.00 0.00 ATOM 611 CG GLU 156-2.252-10.532-2.345 1.00 0.00 ATOM 612 1HG GLU 156-2. 696-11.310-2.942 1.00 0.00 ATOM 613 2HG GLU 156-3.032-9.943-1.887 1.00 0.00 ATOM 614 QG GLU 156-2.864-10.627-2.415 1.00 0.00 ATOM 615 CD GLU 156-1.431-11.174-1.243 1.00 0.00 ATOM 616 OE1 GLU 156-1.556-10.741-0.078 1.00 0.00 ATOM 617 OE2 GLU 156-0.640-12.091-1.539 1.00 0.00 ATOM 618 C GLU 156 0.838-8.697-3.791 1.00 0.00 ATOM 619 O GLU 156 1.654-9.402-4.360 1.00 0.00 ATOM 620 N THR 157 0.696-7.400-4.061 1.00 0.00 ATOM 621 H THR 157 0.031-6.872-3.562 1.00 0.00 ATOM 622 CA THR 157 1.526-6.745-5.074 1.00 0.00 ATOM 623 HA THR 157 1.330-7.227-6.021 1.00 0.00 ATOM 624 CB THR 157 1.173-5.253-5.184 1.00 0.00 ATOM 625 HB THR 157 1.371-4.776-4.234 1.00 0.00 ATOM 626 QG2 THR 157 2.153-4.344-6.499 1.00 0.00 ATOM 627 OG1 THR 157-0.199-5.078-5.492 1.00 0.00 ATOM 628 1HG THR 157-0.740-5.443-4.778 1.00 0.00 ATOM 629 CG2 THR 157 1.965-4.518-6.245 1.00 0.00 ATOM 630 1HG2 THR 157 1.304-4.225-7.048 1.00 0.00 ATOM 631 2HG2 THR 157 2.737-5.168-6.634 1.00 0.00 ATOM 632 3HG2 THR 157 2.418-3.639-5.813 1.00 0.00 ATOM 633 C THR 157 3.012-6.919-4.735 1.00 0.00 ATOM 634 O THR 157 3.855-7.089-5.617 1.00 0.00 ATOM 635 N CYS 158 3.329-6.885-3.448 1.00 0.00 ATOM 636 H CYS 158 2.617-6.746-2.779 1.00 0.00 ATOM 637 CA CYS 158 4.707-7. 053-3.005 1.00 0.00 ATOM 638 HA CYS 158 5.347-6.600-3.745 1.00 0.00 ATOM 639 CB CYS 158 4.908-6.332-1.673 1.00 0.00 ATOM 640 1HB CYS 158 5.775-6.729-1.178 1.00 0.00 ATOM 641 2HB CYS 158 4.043-6.502-1.052 1.00 0.00 ATOM 642 QB CYS 158 4.909-6.616-1.115 1.00 0.00 ATOM 643 SG CYS 158 5.126-4.522-1.845 1.00 0.00 ATOM 644 C CYS 158 5.078-8.536-2.891 1.00 0.00 ATOM 645 O CYS 158 6.147-8.945-3.344 1.00 0.00 ATOM 646 N SER 159 4.196-9.329-2.281 1.00 0.00 ATOM 647 H SER 159 3.368-8.936-1.932 1.00 0.00 ATOM 648 CA SER 159 4.419-10.765-2.096 1.00 0.00 ATOM 649 HA SER 159 5.375-10.886-1.610 1.00 0.00 ATOM 650 CB SER 159 3.335-11.357-1.195 1.00 0.00 ATOM 651 1HB SER 159 3.484-12.425-1.116 1.00 0.00 ATOM 652 2HB SER 159 2.364-11.161-1.629 1.00 0.00 ATOM 653 QB SER 159 2.924-11.793-1.373 1.00 0.00 ATOM 654 OG SER 159 3.383-10.786 0.108 1.00 0.00 ATOM 655 HG SER 159 4.302-10.628 0.349 1.00 0.00 ATOM 656 C SER 159 4.454-11.527-3.423 1.00 0.00 ATOM 657 O SER 159 5.087-12.576-3.511 1.00 0.00 ATOM 658 N GLU 160 3.785-10.996-4.450 1.00 0.00 ATOM 659 H GLU 160 3.297-10.153-4.321 1.00 0.00 ATOM 660 CA GLU 160 3.766-11.630-5.769 1.00 0.00 ATOM 661 HA GLU 160 3.406-12.642-5.655 1.00 0. 00 ATOM 662 CB GLU 160 2.843-10.858-6.724 1.00 0.00

ATOM 663 1HB GLU 160 3.206-9.843-6.810 1.00 0.00 ATOM 664 2HB GLU 160 1.849-10.836-6.304 1.00 0.00 ATOM 665 QB GLU 160 2.527-10.340-6.557 1.00 0.00 ATOM 666 CG GLU 160 2.751-11.444-8.127 1.00 0.00 ATOM 667 1HG GLU 160 1.711-11.509-8.410 1.00 0.00 ATOM 668 2HG GLU 160 3.187-12.432-8.121 1.00 0.00 ATOM 669 QG GLU 160 2.449-11.971-8.266 1.00 0.00 ATOM 670 CD GLU 160 3.481-10.599-9.149 1.00 0.00 ATOM 671 OE1 GLU 160 4.003-11.167-10.131 1.00 0.00 ATOM 672 OE2 GLU 160 3.567-9.372-8.952 1.00 0.00 ATOM 673 C GLU 160 5.182-11.661-6.325 1.00 0.00 ATOM 674 O GLU 160 5.548-12.516-7.133 1.00 0.00 ATOM 675 N LYS+ 161 5.982-10.719-5. 862 1.00 0. 00 ATOM 676 H LYS+ 161 5.637-10.078-5.208 1.00 0.00 ATOM 677 CA LYS+ 161 7.356-10.630-6.274 1.00 0.00 ATOM 678 HA LYS+ 161 7.488-11.259-7.142 1.00 0.00 ATOM 679 CB LYS+ 161 7.715-9.185-6.628 1.00 0.00 ATOM 680 1HB LYS+ 161 8.147-8.713-5.758 1.00 0.00 ATOM 681 2HB LYS+ 161 6.815-8.658-6.900 1.00 0.00 ATOM 682 QB LYS+ 161 7.481-8.686-6.329 1.00 0.00 ATOM 683 CG LYS+ 161 8.714-9.079-7.774 1.00 0.00 ATOM 684 1HG LYS+ 161 9.118-10.062-7.974 1.00 0.00 ATOM 685 2HG LYS+ 161 9.514-8.418-7.477 1.00 0.00 ATOM 686 QG LYS+ 161 9.316-9.240-7.726 1.00 0.00 ATOM 687 CD LYS+ 161 8.077-8. 535-9.056 1.00 0.00 ATOM 688 1HD LYS+ 161 8.649-8.887-9.903 1.00 0.00 ATOM 689 2HD LYS+ 161 8.112-7.456-9.028 1.00 0.00 ATOM 690 QD LYS+ 161 8.380-8.172-9.466 1.00 0.00 ATOM 691 CE LYS+ 161 6.618-8.968-9.230 1.00 0.00 ATOM 692 1HE LYS+ 161 6.213-8.476-10.103 1.00 0.00 ATOM 693 2HE LYS+ 161 6.057-8.659-8.359 1.00 0.00 ATOM 694 QE LYS+ 161 6.135-8.568-9.231 1.00 0.00 ATOM 695 NZ LYS+ 161 6.468-10.443-9.395 1.00 0.00 ATOM 696 lHZ LYS+ 161 7.209-10.822-10.010 1.00 0.00 ATOM 697 2HZ LYS+ 161 5.529-10.660-9.822 1.00 0.00 ATOM 698 3HZ LYS+ 161 6.514-10.917-8.469 1.00 0.00 ATOM 699 QZ LYS+ 161 6.417-10.800-9.434 1.00 0.00 ATOM 700 C LYS+ 161 8.232-11.154-5.146 1.00 0.00 ATOM 701 O LYS+ 161 7.909-12.160-4.522 1.00 0.00 ATOM 702 N SER 162 9.333-10.485-4.884 1.00 0.00 ATOM 703 H SER 162 9.554-9. 693-5.407 1.00 0.00 ATOM 704 CA SER 162 10.225-10.916-3.831 1.00 0.00 ATOM 705 HA SER 162 9.862-11.862-3.463 1.00 0.00 ATOM 706 CB SER 162 11.633-11.116-4.394 1.00 0.00 ATOM 707 1HB SER 162 11.970-12. 117-4.165 1.00 0.00 ATOM 708 2HB SER 162 12.303-10.399-3.939 1.00 0.00 ATOM 709 QB SER 162 12.136-11.258-4.052 1.00 0.00 ATOM 710 OG SER 162 11.649-10. 934-5.806 1.00 0.00 ATOM 711 HG SER 162 12.317-11.508-6.192 1.00 0.00 ATOM 712 C SER 162 10.257-9. 919-2.675 1.00 0.00 ATOM 713 O SER 162 11.330-9.524-2.232 1.00 0.00 ATOM 714 N THR 163 9.088-9.504-2.178 1.00 0.00 ATOM 715 H THR 163 8.244-9.838-2.561 1.00 0.00 ATOM 716 CA THR 163 9.051-8.564-1.057 1.00 0.00 ATOM 717 HA THR 163 9.965-8.696-0.492 1.00 0.00 ATOM 718 CB THR 163 8.984-7.111-1.530 1.00 0.00 ATOM 719 HB THR 163 8.856-6.484-0.652 1.00 0.00 ATOM 720 QG2 THR 163 10.520-6.524-2.428 1.00 0.00 ATOM 721 OG1 THR 163 7.886-6.908-2.400 1.00 0.00 ATOM 722 1HG THR 163 7.616-7.758-2.779 1.00 0.00 ATOM 723 CG2 THR 163 10.225-6.635-2.255 1.00 0.00 ATOM 724 1HG2 THR 163 9.955-6.283-3.239 1.00 0.00 ATOM 725 2HG2 THR 163 10.924-7.456-2.346 1.00 0.00 ATOM 726 3HG2 THR 163 10.683-5.832-1.697 1.00 0.00 ATOM 727 C THR 163 7.876-8.847-0.122 1.00 0.00 ATOM 728 O THR 163 6.877-9.454-0. 508 1.00 0.00 ATOM 729 N ASN 164 8.009-8.393 1. 116 1.00 0.00 ATOM 730 H ASN 164 8.839-7.917 1.357 1.00 0.00 ATOM 731 CA ASN 164 6.975-8.582 2.138 1. 00 0. 00 ATOM 732 HA ASN 164 6.114-9.036 1.660 1.00 0.00 ATOM 733 CB ASN 164 7.488-9.505 3.251 1.00 0.00 ATOM 734 1HB ASN 164 7.292-10.529 2.977 1.00 0.00

ATOM 735 2HB ASN 164 6. 968-9. 277 4. 170 1. 00 0. 00 ATOM 736 QB ASN 164 7. 130-9. 903 3. 573 1. 00 0. 00 ATOM 737 CG ASN 164 8. 981-9. 354 3. 494 1. 00 0. 00 ATOM 738 ODE ASN 164 9. 675-10. 326 3. 761 1. 00 0. 00 ATOM 739 ND2 ASN 164 9. 475-8. 125 3. 421 1. 00 0. 00 ATOM 740 1HD2 ASN 164 8. 853-7. 390 3. 237 1. 00 0. 00 ATOM 741 2HD2 ASN 164 10. 440-8. 009 3. 493 1. 00 0. 00 ATOM 742 QD2 ASN 164 9. 646-7. 700 3. 365 1. 00 0. 00 ATOM 743 C ASN 164 6. 565-7. 244 2. 747 1. 00 0. 00 ATOM 744 0 ASN 164 7. 417-6. 418 3. 066 1. 00 0. 00 ATOM 745 N LEU 165 5. 265-7. 029 2. 905 1. 00 0. 00 ATOM 746 H LEU 165 4. 631-7. 722 2. 634 1. 00 0. 00 ATOM 747 CA LEU 165 4. 755-5. 779 3. 475 1. 00 0. 00 ATOM 748 HA LEU 165 5. 251-4. 955 2. 983 1. 00 0. 00 ATOM 749 CB LEU 165 3. 248-5. 659 3. 246 1. 00 0. 00 ATOM 750 1HB LEU 165 2. 769-5. 526 4. 205 1. 00 0. 00 ATOM 751 2HB LEU 165 2. 893-6. 579 2. 806 1. 00 0. 00 ATOM 752 QB LEU 165 2. 831-6. 053 3. 505 1. 00 0. 00 ATOM 753 CG LEU 165 2. 821-4. 509 2. 353 1. 00 0. 00 ATOM 754 HG LEU 165 3. 364-3. 618 2. 632 1. 00 0. 00 ATOM 755 QD1 LEU 165 3. 218-4. 901 0. 566 1. 00 0. 00 ATOM 756 QD2 LEU 165 0. 984-4. 170 2. 569 1. 00 0. 00 ATOM 757 CRI LEU 165 3. 143-4. 826 0. 911 1. 00 0. 00 ATOM 758 1HD1 LEU 165 3. 464-5. 853 0. 831 1. 00 0. 00 ATOM 759 2HD1 LEU 165 3. 930-4. 173 0. 565 1. 00 0. 00 ATOM 760 3HD1 LEU 165 2. 260-4. 676 0. 304 1. 00 0. 00 ATOM 761 CD2 LEU 165 1. 337-4. 235 2. 528 1. 00 0. 00 ATOM 762 1HD2 LEU 165 1. 066-3. 349 1. 974 1. 00 0. 00 ATOM 763 2HD2 LEU 165 1. 119-4. 085 3. 576 1. 00 0. 00 ATOM 764 3HD2 LEU 165 0. 768-5. 076 2. 159 1. 00 0. 00 ATOM 765 QQD LEU 165 2. 101-4. 536 1. 568 1. 00 0. 00 ATOM 766 C LEU 165 5. 031-5. 685 4. 963 1. 00 0. 00 ATOM 767 0 LEU 165 4. 671-6. 577 5. 728 1. 00 0. 00 ATOM 768 N HIS+ 166 5. 653-4. 590 5. 359 1. 00 0. 00 ATOM 769 H HIS+ 166 5. 904-3. 912 4. 693 1. 00 0. 00 ATOM 770 CA HIS+ 166 5. 964-4. 350 6. 755 1. 00 0. 00 ATOM 771 HA HIS+ 166 5. 669-5. 224 7. 316 1. 00 0. 00 ATOM 772 CB HIS+ 166 7. 471-4. 125 6. 926 1. 00 0. 00 ATOM 773 1HB HIS+ 166 7. 766-3. 271 6. 332 1. 00 0. 00 ATOM 774 2HB HIS+ 166 8. 000-4. 998 6. 578 1. 00 0. 00 ATOM 775 QB HIS+ 166 7. 883-4. 135 6. 455 1. 00 0. 00 ATOM 776 CG HIS+ 166 7. 890-3. 866 8. 338 1. 00 0. 00 ATOM 777 ND1 HIS+ 166 7. 821-4. 812 9. 338 1. 00 0. 00 ATOM 778 CD2 HIS+ 166 8. 373-2. 746 8. 915 1. 00 0. 00 ATOM 779 1HD HIS+ 166 7. 503-5. 734 9. 234 1. 00 0. 00 ATOM 780 CE1 HIS+ 166 8. 245-4. 279 10. 471 1. 00 0. 00 ATOM 781 NE2 HIS+ 166 8. 587-3. 021 10. 241 1. 00 0. 00 ATOM 782 2HD HIS+ 166 8. 540-1. 793 8. 421 1. 00 0. 00 ATOM 783 1HE HIS+ 166 8. 302-4. 784 11. 424 1. 00 0. 00 ATOM 784 2HE HIS+ 166 8. 720-2. 342 10. 935 1. 00 0. 00 ATOM 785 C HIS+ 166 5. 173-3. 143 7. 267 1. 00 0. 00 ATOM 786 0 HIS+ 166 4. 536-3. 211 8. 319 1. 00 0. 00 ATOM 787 N ASP 167 5. 219-2. 041 6. 516 1. 00 0. 00 ATOM 788 H ASP 167 5. 745-2. 048 5. 687 1. 00 0. 00 ATOM 789 CA ASP 167 4. 510-0. 817 6. 909 1. 00 0. 00 ATOM 790 HA ASP 167 3. 994-1. 022 7. 835 1. 00 0. 00 ATOM 791 CB ASP 167 5. 490 0. 345 7. 140 1. 00 0. 00 ATOM 792 1HB ASP 167 5. 085 0. 996 7. 902 1. 00 0. 00 ATOM 793 2HB ASP 167 5. 593 0. 902 6. 222 1. 00 0. 00 ATOM 794 QB ASP 167 5. 339 0. 949 7. 062 1. 00 0. 00 ATOM 795 CC ASP 167 6. 870-0. 098 7. 579 1. 00 0. 00 ATOM 796 ODE ASP 167 7. 650-0. 564 6. 719 1. 00 0. 00 ATOM 797 OD2 ASP 167 7. 175 0. 024 8. 783 1. 00 0. 00 ATOM 798 C ASP 167 3. 483-0. 388 5. 862 1. 00 0. 00 ATOM 799 0 ASP 167 3. 801 0. 342 4. 927 1. 00 0. 00 ATOM 800 N TYR 168 2. 249-0. 837 6. 028 1. 00 0. 00 ATOM 801 H TYR 168 2. 054-1. 408 6. 800 1. 00 0. 00 ATOM 802 CA TYR 168 1. 160-0. 488 5. 112 1. 00 0. 00 ATOM 803 HA TYR 168 1. 591-0. 241 4. 142 1. 00 0. 00 ATOM 804 CB TYR 168 0. 205-1. 675 4. 953 1. 00 0. 00 ATOM 805 1HB TYR 168 0. 603-2. 351 4. 211 1. 00 0. 00 ATOM 806 2HB TYR 168-0. 757-1. 311 4. 622 1. 00 0. 00

ATOM 807 QB TYR 168-0.077-1. 831 4.416 1.00 0.00 ATOM 808 QD TYR 168-0.028-2.542 6.386 1.00 0.00 ATOM 809 QE TYR 168-0.360-3.782 8.481 1.00 0.00 ATOM 810 QR TYR 168-0.194-3.162 7.433 1.00 0.00 ATOM 811 CG TYR 168-0.006-2.453 6. 236 1.00 0.00 ATOM 812 CD1 TYR 168 0.845-3.493 6.593 1.00 0.00 ATOM 813 1HD TYR 168 1.662-3.753 5.936 1.00 0.00 ATOM 814 CE1 TYR 168 0.662-4.192 7.769 1.00 0.00 ATOM 815 1HE TYR 168 1.335-4.996 8.030 1.00 0.00 ATOM 816 CZ TYR 168-0.380-3.857 8.606 1.00 0.00 ATOM 817 CE2 TYR 168-1.238-2.831 8.275 1.00 0.00 ATOM 818 2HE TYR 168-2.054-2.568 8.932 1.00 0.00 ATOM 819 CD2 TYR 168-1.048-2.135 7.098 1.00 0.00 ATOM 820 2HD TYR 168-1.718-1.330 6. 836 1.00 0.00 ATOM 821 OH TYR 168-0.568-4.552 9.776 1.00 0.00 ATOM 822 HH TYR 168 0.055-4.239 10.439 1.00 0.00 ATOM 823 C TYR 168 0.387 0.725 5.624 1.00 0.00 ATOM 824 O TYR 168 0.269 0.938 6.830 1.00 0.00 ATOM 825 N GLY 169-0. 159 1.493 4.700 1.00 0.00 ATOM 826 H GLY 169-0.045 1.259 3.754 1.00 0.00 ATOM 827 CA GLY 169-0.938 2.661 5.052 1.00 0.00 ATOM 828 1HA GLY 169-0.298 3.532 5.048 1.00 0.00 ATOM 829 2HA GLY 169-1.354 2.529 6.040 1.00 0.00 ATOM 830 QA GLY 169-0.826 3.030 5.544 1.00 0.00 ATOM 831 C GLY 169-2.053 2.862 4.059 1.00 0.00 ATOM 832 O GLY 169-1.884 2.567 2.884 1.00 0.00 ATOM 833 N MET 170-3.197 3.333 4.510 1.00 0.00 ATOM 834 H MET 170-3.292 3.543 5.461 1.00 0.00 ATOM 835 CA MET 170-4.327 3.538 3.614 1.00 0.00 ATOM 836 HA MET 170-3.979 3.384 2.590 1.00 0.00 ATOM 837 CB MET 170-5.450 2.542 3.933 1.00 0.00 ATOM 838 1HB MET 170-6.398 3.008 3.705 1.00 0.00 ATOM 839 2HB MET 170-5.421 2.313 4.987 1.00 0.00 ATOM 840 QB MET 170-5.910 2.660 4.346 1.00 0.00 ATOM 841 CG MET 170-5.368 1.231 3.161 1.00 0.00 ATOM 842 1HG MET 170-5.520 1.443 2.111 1.00 0.00 ATOM 843 2HG MET 170-6.154 0.578 3.508 1.00 0.00 ATOM 844 QG MET 170-5.837 1.010 2.809 1.00 0.00 ATOM 845 SD MET 170-3.788 0.381 3.352 1.00 0.00 ATOM 846 QE MET 170-4.358-1.367 4.458 1.00 0.00 ATOM 847 CE MET 170-4.262-1.073 4.273 1.00 0.00 ATOM 848 1HE MET 170-3.425-1.413 4.865 1.00 0.00 ATOM 849 2HE MET 170-4. 557-1.853 3.587 1.00 0.00 ATOM 850 3HE MET 170-5.090-0.833 4.923 1.00 0.00 ATOM 851 C MET 170-4.842 4.961 3.757 1.00 0.00 ATOM 852 O MET 170-5.211 5.388 4.851 1.00 0.00 ATOM 853 N LEU 171-4.849 5.695 2.659 1.00 0.00 ATOM 854 H LEU 171-4.529 5.302 1.817 1.00 0.00 ATOM 855 CA LEU 171-5.298 7.080 2.678 1.00 0.00 ATOM 856 HA LEU 171-5.616 7.305 3.685 1.00 0.00 ATOM 857 CB LEU 171-4.135 8.009 2.309 1.00 0.00 ATOM 858 1HB LEU 171-3.396 7.953 3.095 1.00 0.00 ATOM 859 2HB LEU 171-4.511 9.020 2.264 1.00 0.00 ATOM 860 QB LEU 171-3.954 8.486 2.679 1.00 0.00 ATOM 861 CG LEU 171-3.443 7.693 0.980 1.00 0.00 ATOM 862 HG LEU 171-4.119 7.135 0.351 1.00 0.00 ATOM 863 QD1 LEU 171-2.990 9.277 0.083 1.00 0.00 ATOM 864 QD2 LEU 171-1.904 6.650 1.257 1.00 0.00 ATOM 865 CD1 LEU 171-3.078 8.973 0.256 1.00 0.00 ATOM 866 1HD1 LEU 171-2. 711 9.698 0.967 1.00 0.00 ATOM 867 2HD1 LEU 171-3.950 9.368-0.244 1.00 0.00 ATOM 868 3HD1 LEU 171-2.309 8.766-0.474 1.00 0.00 ATOM 869 CD2 LEU 171-2.200 6.850 1.204 1.00 0. 00 ATOM 870 1HD2 LEU 171-1.879 6.943 2.233 1.00 0.00 ATOM 871 2HD2 LEU 171-1.410 7.193 0.551 1.00 0.00 ATOM 872 3HD2 LEU 171-2.421 5.816 0.989 1.00 0.00 ATOM 873 QQD LEU 171-2.447 7.964 0.670 1.00 0.00 ATOM 874 C LEU 171-6.475 7.307 1.732 1.00 0.00 ATOM 875 O LEU 171-7. 098 6.355 1. 264 1.00 0.00 ATOM 876 N LEU 172-6.756 8.585 1.462 1.00 0.00 ATOM 877 H LEU 172-6.203 9.278 1.877 1.00 0.00 ATOM 878 CA LEU 172-7.847 9. 004 0.570 1.00 0.00

ATOM 879 HA LEU 172-7.991 10.064 0.715 1.00 0.00 ATOM 880 CB LEU 172-7.462 8.764-0.896 1.00 0.00 ATOM 881 1HB LEU 172-8. 310 8.319-1.395 1.00 0.00 ATOM 882 2HB LEU 172-6.644 8.060-0.923 1.00 0.00 ATOM 883 QB LEU 172-7.477 8.189-1.159 1.00 0.00 ATOM 884 CG LEU 172-7.049 10.013-1.682 1.00 0.00 ATOM 885 HG LEU 172-6.557 9.708-2.595 1.00 0.00 ATOM 886 QD1 LEU 172-8.557 11.029-2.154 1.00 0.00 ATOM 887 QD2 LEU 172-5.839 11.060-0.696 1.00 0.00 ATOM 888 CD1 LEU 172-8.269 10.834-2.063 1.00 0.00 ATOM 889 1HD1 LEU 172-8. 331 11.702-1.424 1.00 0.00 ATOM 890 2HD1 LEU 172-9.158 10.234-1.946 1.00 0.00 ATOM 891 3HD1 LEU 172-8.180 11.151-3.092 1. 00 0.00 ATOM 892 CD2 LEU 172-6.072 10.860-0.883 1.00 0.00 ATOM 893 1HD2 LEU 172-6. 499 11.836-0.709 1.00 0.00 ATOM 894 2HD2 LEU 172-5. 149 10.965-1.440 1.00 0.00 ATOM 895 3HD2 LEU 172-5.868 10.380 0.062 1.00 0.00 ATOM 896 QQD LEU 172-7.198 11.044-1.425 1.00 0.00 ATOM 897 C LEU 172-9.168 8.293 0.876 1.00 0.00 ATOM 898 O LEU 172-9.700 7.584 0.025 1.00 0.00 ATOM 899 N PRO 173-9.736 8.480 2.081 1.00 0.00 ATOM 900 CD PRO 173-9.206 9.325 3.170 1.00 0.00 ATOM 901 CA PRO 173-11.007 7.844 2.445 1.00 0.00 ATOM 902 HA PRO 173-10.950 6.769 2.351 1.00 0.00 ATOM 903 CB PRO 173-11.197 8.222 3.918 1.00 0.00 ATOM 904 1HB PRO 173-10.860 7.410 4.546 1.00 0.00 ATOM 905 2HB PRO 173-12.243 8.418 4.108 1.00 0.00 ATOM 906 QB PRO 173-11.552 7.914 4.327 1.00 0.00 ATOM 907 CG PRO 173-10.368 9.445 4.117 1.00 0.00 ATOM 908 1HG PRO 173-10.016 9.487 5. 138 1.00 0.00 ATOM 909 2HG PRO 173-10.951 10.325 3.886 1.00 0.00 ATOM 910 QG PRO 173-10.484 9.906 4.512 1.00 0.00 ATOM 911 1HD PRO 173-8.370 8.846 3.657 1.00 0.00 ATOM 912 2HD PRO 173-8.921 10.299 2.798 1.00 0.00 ATOM 913 QD PRO 173-8.646 9.572 3.227 1.00 0.00 ATOM 914 C PRO 173-12.171 8.362 1.605 1.00 0.00 ATOM 915 O PRO 173-12.177 9.520 1.179 1.00 0.00 ATOM 916 N CYS 174-13.150 7.505 1.364 1.00 0.00 ATOM 917 H CYS 174-13.088 6.594 1.728 1.00 0.00 ATOM 918 CA CYS 174-14. 319 7.882 0.576 1.00 0.00 ATOM 919 HA CYS 174-14.272 8.949 0.411 1.00 0.00 ATOM 920 CB CYS 174-14.323 7.170-0.777 1.00 0.00 ATOM 921 1HB CYS 174-13. 805 7.784-1.498 1.00 0.00 ATOM 922 2HB CYS 174-15.344 7.033-1.098 1. 00 0.00 ATOM 923 QB CYS 174-14.575 7.408-1.298 1.00 0.00 ATOM 924 SG CYS 174-13.525 5.534-0.767 1.00 0.00 ATOM 925 C CYS 174-15.598 7.565 1.336 1.00 0.00 ATOM 926 O CYS 174-16.616 8.231 1.164 1.00 0.00 ATOM 927 N GLY 175-15. 531 6.551 2.185 1.00 0.00 ATOM 928 H GLY 175-14.686 6.064 2.288 1.00 0.00 ATOM 929 CA GLY 175-16.680 6.167 2.979 1.00 0.00 ATOM 930 1HA GLY 175-17.077 5.237 2.603 1.00 0.00 ATOM 931 2HA GLY 175-17.437 6.935 2.901 1.00 0.00 ATOM 932 QA GLY 175-17.257 6.086 2.752 1.00 0.00 ATOM 933 C GLY 175-16.298 5.992 4.428 1.00 0.00 ATOM 934 O GLY 175-15.226 6.432 4.834 1.00 0.00 ATOM 935 N ILE 176-17.160 5.343 5.203 1.00 0.00 ATOM 936 H ILE 176-17.994 5.008 4.817 1.00 0.00 ATOM 937 CA ILE 176-16.881 5.106 6.615 1.00 0.00 ATOM 938 HA ILE 176-16.716 6.062 7.091 1.00 0.00 ATOM 939 CB ILE 176-18.064 4.401 7.315 1.00 0.00 ATOM 940 HB ILE 176-17.998 3.345 7.100 1.00 0.00 ATOM 941 QG2 ILE 176-17.960 4.625 9.179 1.00 0.00 ATOM 942 CG2 ILE 176-17.979 4.583 8.822 1.00 0.00 ATOM 943 1HG2 ILE 176-18.609 5.408 9.121 1.00 0.00 ATOM 944 2HG2 ILE 176-16.957 4.788 9.104 1.00 0.00 ATOM 945 3HG2 ILE 176-18.314 3.680 9.312 1.00 0.00 ATOM 946 CG1 ILE 176-19.399 4.937 6.792 1.00 0.00 ATOM 947 1HG1 ILE 176-19.293 5.201 5.751 1.00 0.00 ATOM 948 2HG1 ILE 176-19.671 5.816 7.356 1.00 0.00 ATOM 949 QG1 ILE 176-19.482 5.508 6.553 1.00 0.00 ATOM 950 QD1 ILE 176-20.803 3.706 6.939 1.00 0.00

ATOM 951 CD1 ILE 176-20.532 3.943 6.910 1.00 0.00 ATOM 952 1HD1 ILE 176-20. 993 4.038 7.883 1.00 0.00 ATOM 953 2HD1 ILE 176-20.147 2.941 6.791 1.00 0.00 ATOM 954 3HD1 ILE 176-21.267 4.140 6.143 1.00 0.00 ATOM 955 C ILE 176-15. 621 4.253 6.761 1.00 0.00 ATOM 956 O ILE 176-14.674 4.639 7.443 1.00 0.00 ATOM 957 N ASP 177-15.613 3.107 6.086 1.00 0.00 ATOM 958 H ASP 177-16.390 2.870 5.544 1.00 0.00 ATOM 959 CA ASP 177-14.464 2.209 6.107 1.00 0.00 ATOM 960 HA ASP 177-13.651 2.725 6.599 1.00 0.00 ATOM 961 CB ASP 177-14.771 0.921 6.876 1.00 0.00 ATOM 962 1HB ASP 177-15.332 0.253 6.239 1.00 0.00 ATOM 963 2HB ASP 177-15.360 1. 160 7.748 1.00 0.00 ATOM 964 QB ASP 177-15.346 0.706 6.993 1.00 0.00 ATOM 965 CG ASP 177-13.511 0.203 7.331 1.00 0.00 ATOM 966 OD1 ASP 177-12. 405 0.587 6. 885 1.00 0.00 ATOM 967 OD2 ASP 177-13.628-0.751 8.124 1.00 0.00 ATOM 968 C ASP 177-14.037 1.876 4.681 1.00 0.00 ATOM 969 O ASP 177-13.889 0.709 4.305 1.00 0.00 ATOM 970 N LYS+ 178-13.837 2.913 3.883 1.00 0.00 ATOM 971 H LYS+ 178-13.965 3.819 4.238 1.00 0.00 ATOM 972 CA LYS+ 178-13.412 2.745 2.501 1.00 0.00 ATOM 973 HA LYS+ 178-12.936 1.778 2.419 1.00 0.00 ATOM 974 CB LYS+ 178-14.584 2.818 1.519 1.00 0.00 ATOM 975 1HB LYS+ 178-14.225 2.544 0.537 1.00 0.00 ATOM 976 2HB LYS+ 178-14.937 3.833 1.486 1.00 0.00 ATOM 977 QB LYS+ 178-14.581 3.188 1.011 1.00 0.00 ATOM 978 CG LYS+ 178-15. 752 1.904 1.876 1.00 0.00 ATOM 979 1HG LYS+ 178-16.613 2.514 2.111 1.00 0.00 ATOM 980 2HG LYS+ 178-15.481 1.315 2.741 1.00 0.00 ATOM 981 QG LYS+ 178-16.047 1.914 2.426 1.00 0.00 ATOM 982 CD LYS+ 178-16.107 0.964 0.732 1.00 0.00 ATOM 983 1HD LYS+ 178-15.567 1.271-0.153 1.00 0.00 ATOM 984 2HD LYS+ 178-17.169 1.026 0.546 1.00 0.00 ATOM 985 QD LYS+ 178-16.368 1.148 0.196 1.00 0.00 ATOM 986 CE LYS+ 178-15.747-0.484 1.054 1.00 0.00 ATOM 987 1HE LYS+ 178-16.449-0.864 1.781 1.00 0.00 ATOM 988 2HE LYS+ 178-14.750-0.510 1.471 1.00 0.00 ATOM 989 QE LYS+ 178-15.600-0.687 1.626 1.00 0.00 ATOM 990 NZ LYS+ 178-15.786-1.349-0.160 1.00 0.00 ATOM 991 1HZ LYS+ 178-16.753-1.674-0.347 1.00 0.00 ATOM 992 2HZ LYS+ 178-15.172-2.192-0.031 1.00 0.00 ATOM 993 3HZ LYS+ 178-15.440-0.825-0.995 1.00 0.00 ATOM 994 QZ LYS+ 178-15.789-1.564-0.458 1.00 0.00 ATOM 995 C LYS+ 178-12.388 3.800 2.163 1.00 0.00 ATOM 996 O LYS+ 178-12.576 4.983 2.447 1.00 0.00 ATOM 997 N PHE 179-11.302 3.357 1.570 1.00 0.00 ATOM 998 H PHE 179-11.224 2.400 1.380 1.00 0.00 ATOM 999 CA PHE 179-10.216 4.242 1.206 1.00 0.00 ATOM 1000 HA PHE 179-10.513 5.253 1.437 1.00 0.00 ATOM 1001 CB PHE 179-8. 959 3.892 2.002 1.00 0.00 ATOM 1002 1HB PHE 179-8.209 4.626 1.792 1.00 0.00 ATOM 1003 2HB PHE 179-8.595 2.929 1.683 1.00 0.00 ATOM 1004 QB PHE 179-8.402 3.777 1.737 1.00 0.00 ATOM 1005 QD PHE 179-9.189 3.842 3.659 1.00 0.00 ATOM 1006 QE PHE 179-9.538 3.784 6.094 1.00 0.00 ATOM 1007 QR PHE 179-9.434 3.801 5.364 1.00 0.00 ATOM 1008 CG PHE 179-9.165 3.848 3.493 1.00 0.00 ATOM 1009 CD1 PHE 179-8.799 4.924 4.285 1.00 0.00 ATOM 1010 1HD PHE 179-8.359 5.795 3.824 1.00 0.00 ATOM 1011 CE1 PHE 179-8.994 4.894 5.653 1.00 0.00 ATOM 1012 1HE PHE 179-8.704 5.740 6.259 1.00 0.00 ATOM 1013 CZ PHE 179-9.559 3.781 6.245 1.00 0.00 ATOM 1014 HZ PHE 179-9.714 3.756 7.314 1.00 0.00 ATOM 1015 CE2 PHE 179-9.926 2.700 5.468 1.00 0.00 ATOM 1016 2HE PHE 179-10.372 1.829 5.929 1.00 0.00 ATOM 1017 CD2 PHE 179-9.730 2.736 4.101 1.00 0.00 ATOM 1018 2HD PHE 179-10.019 1.889 3.495 1.00 0.00 ATOM 1019 C PHE 179-9.913 4.135-0.270 1.00 0.00 ATOM 1020 O PHE 179-10.536 3.352-0.985 1.00 0.00 ATOM 1021 N ARG+ 180-8.935 4.908-0.712 1.00 0.00 ATOM 1022 H ARG+ 180-8.470 5.495-0.078 1.00 0.00

ATOM 1023 CA ARG+ 180-8.515 4.897-2.102 1.00 0.00 ATOM 1024 HA ARG+ 180-8.891 3.992-2.559 1.00 0.00 ATOM 1025 CB ARG+ 180-9.078 6.109-2.853 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.782 6.036-3.889 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.654 7.007-2.435 1.00 0.00 ATOM 1028 QB ARG+ 180-8.718 6.521-3.162 1.00 0.00 ATOM 1029 CG ARG+ 180-10.592 6.222-2.799 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.915 6.094-1.776 1.00 0.00 ATOM 1031 2HG ARG+ 180-11. 023 5.442-3.412 1.00 0.00 ATOM 1032 QG ARG+ 180-10.969 5.768-2.594 1.00 0.00 ATOM 1033 CD ARG+ 180-11.075 7.569-3.307 1.00 0.00 ATOM 1034 1HD ARG+ 180-12.008 7.425-3.832 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.336 7.966-3.989 1.00 0.00 ATOM 1036 QD ARG+ 180-11.172 7.695-3.911 1.00 0.00 ATOM 1037 NE ARG+ 180-11.281 8.523-2.218 1.00 0.00 ATOM 1038 HE ARG+ 180-10.976 8.254-1.317 1.00 0.00 ATOM 1039 CZ ARG+ 180-11.852 9.716-2.378 1.00 0.00 ATOM 1040 NH1 ARG+ 180-12.260 10.097-3.584 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12. 140 9.487-4.369 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-12.684 10.995-3.714 1.00 0.00 ATOM 1043 QH1 ARG+ 180-12.412 10.241-4.042 1.00 0. 00 ATOM 1044 NH2 ARG+ 180-12.020 10.522-1.336 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-11.721 10.231-0.419 1.00 0. 00 ATOM 1046 2HH2 ARG+ 180-12.442 11.421-1.455 1.00 0.00 ATOM 1047 QH2 ARG+ 180-12.082 10.826-0.937 1.00 0.00 ATOM 1048 C ARG+ 180-6.993 4.906-2.198 1.00 0.00 ATOM 1049 O ARG+ 180-6.427 4.634-3.245 1.00 0.00 ATOM 1050 N GLY 181-6.327 5.233-1.104 1.00 0.00 ATOM 1051 H GLY 181-6.815 5.445-0.278 1.00 0.00 ATOM 1052 CA GLY 181-4.880 5.287-1.128 1.00 0.00 ATOM 1053 1HA GLY 181-4.562 6.237-0.722 1.00 0.00 ATOM 1054 2HA GLY 181-4. 551 5.222-2.154 1.00 0.00 ATOM 1055 QA GLY 181-4.557 5.729-1.438 1.00 0.00 ATOM 1056 C GLY 181-4.228 4.178-0.341 1.00 0.00 ATOM 1057 O GLY 181-4.801 3.669 0.620 1.00 0.00 ATOM 1058 N VAL 182-3.020 3.813-0.753 1.00 0. 00 ATOM 1059 H VAL 182-2.626 4.272-1.518 1.00 0.00 ATOM 1060 CA VAL 182-2.253 2.763-0.097 1.00 0.00 ATOM 1061 HA VAL 182-2.583 2.697 0.933 1.00 0.00 ATOM 1062 CB VAL 182-2.447 1.378-0.773 1.00 0.00 ATOM 1063 HB VAL 182-1.657 1.250-1.500 1.00 0.00 ATOM 1064 QG1 VAL 182-2.293-0.003 0.491 1.00 0. 00 ATOM 1065 QG2 VAL 182-4.098 1.255-1.673 1.00 0.00 ATOM 1066 CG1 VAL 182-2.321 0.262 0.249 1.00 0.00 ATOM 1067 1HG1 VAL 182-3.057-0.501 0.040 1.00 0.00 ATOM 1068 2HG1 VAL 182-2.488 0.661 1.239 1.00 0.00 ATOM 1069 3HG1 VAL 182-1. 332-0.167 0.195 1.00 0.00 ATOM 1070 CG2 VAL 182-3.781 1.279-1.502 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.716 1.797-2.446 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.555 1.730-0.897 1.00 0.00 ATOM 1073 3HG2 VAL 182-4.021 0.240-1.675 1.00 0.00 ATOM 1074 QQG VAL 182-3.195 0.626-0.591 1.00 0.00 ATOM 1075 C VAL 182-0.759 3.102-0.125 1.00 0.00 ATOM 1076 O VAL 182-0.195 3.349-1.191 1.00 0.00 ATOM 1077 N GLU 183-0.131 3.100 1.044 1.00 0.00 ATOM 1078 H GLU 183-0.646 2.887 1.859 1.00 0. 00 ATOM 1079 CA GLU 183 1.297 3.387 1.167 1.00 0.00 ATOM 1080 HA GLU 183 1.721 3.406 0.173 1.00 0.00 ATOM 1081 CB GLU 183 1.525 4.742 1.842 1.00 0.00 ATOM 1082 1HB GLU 183 1.617 5.500 1.078 1.00 0.00 ATOM 1083 2HB GLU 183 2.446 4.700 2.404 1.00 0.00 ATOM 1084 QB GLU 183 2.031 5.100 1.741 1.00 0.00 ATOM 1085 CG GLU 183 0.413 5.159 2.791 1.00 0.00 ATOM 1086 1HG GLU 183 0.332 4.422 3.576 1.00 0.00 ATOM 1087 2HG GLU 183-0.515 5.206 2.242 1.00 0.00 ATOM 1088 QG GLU 183-0.092 4.814 2.909 1.00 0.00 ATOM 1089 CD GLU 183 0.670 6.508 3.419 1.00 0.00 ATOM 1090 OE1 GLU 183-0.243 7.037 4.082 1.00 0.00 ATOM 1091 OE2 GLU 183 1.784 7.042 3.234 1.00 0.00 ATOM 1092 C GLU 183 1.969 2.284 1.973 1.00 0.00 ATOM 1093 O GLU 183 1.943 2.290 3.198 1.00 0. 00 ATOM 1094 N PHE 184 2.529 1.311 1. 284 1.00 0.00

ATOM 1095 H PHE 184 2.492 1.334 0.311 1.00 0.00 ATOM 1096 CA PHE 184 3.152 0.177 1.946 1.00 0.00 ATOM 1097 HA PHE 184 3.007 0.303 3.006 1.00 0.00 ATOM 1098 CB PHE 184 2.477-1.129 1.512 1.00 0.00 ATOM 1099 1HB PHE 184 1.574-1.271 2. 087 1.00 0.00 ATOM 1100 2HB PHE 184 3.150-1.950 1.719 1.00 0.00 ATOM 1101 QB PHE 184 2.362-1.611 1.903 1.00 0.00 ATOM 1102 QD PHE 184 2.072-1.207-0.124 1.00 0.00 ATOM 1103 QE PHE 184 1.471-1.371-2.500 1.00 0.00 ATOM 1104 QR PHE 184 1.650-1.324-1.788 1.00 0.00 ATOM 1105 CG PHE 184 2.116-1.199 0.044 1.00 0.00 ATOM 1106 CD1 PHE 184 1.118-0.396-0.494 1.00 0.00 ATOM 1107 1HD PHE 184 0.603 0.308 0.144 1.00 0.00 ATOM 1108 CE1 PHE 184 0.777-0.487-1.830 1.00 0.00 ATOM 1109 1HE PHE 184-0.001 0. 145-2.233 1.00 0.00 ATOM 1110 CZ PHE 184 1.434-1.384-2.648 1.00 0.00 ATOM 1111 HZ PHE 184 1.166-1.464-3.690 1.00 0.00 ATOM 1112 CE2 PHE 184 2.428-2.183-2.129 1.00 0.00 ATOM 1113 2HE PHE 184 2.943-2.887-2.767 1.00 0.00 ATOM 1114 CD2 PHE 184 2.762-2.091-0.793 1.00 0.00 ATOM 1115 2HD PHE 184 3.542-2.721-0.392 1.00 0.00 ATOM 1116 C PHE 184 4.641 0.076 1.668 1.00 0.00 ATOM 1117 O PHE 184 5.106 0.363 0.569 1.00 0.00 ATOM 1118 N VAL 185 5.378-0.368 2.675 1.00 0.00 ATOM 1119 H VAL 185 4.939-0. 596 3.522 1.00 0.00 ATOM 1120 CA VAL 185 6.810-0.550 2.555 1.00 0.00 ATOM 1121 HA VAL 185 7.111-0.192 1.581 1.00 0.00 ATOM 1122 CB VAL 185 7.582 0.241 3.637 1.00 0.00 ATOM 1123 HB VAL 185 7.743-0.411 4.489 1.00 0.00 ATOM 1124 QG1 VAL 185 9.254 0.790 2.992 1.00 0.00 ATOM 1125 QG2 VAL 185 6.596 1.732 4.222 1.00 0.00 ATOM 1126 CG1 VAL 185 8.935 0.684 3.114 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.087 0.286 2.123 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.709 0.322 3.774 1.00 0.00 ATOM 1129 3HG1 VAL 185 8.968 1.763 3.079 1.00 0.00 ATOM 1130 CG2 VAL 185 6.785 1.447 4.109 1.00 0.00 ATOM 1131 1HG2 VAL 185 5.739 1.300 3.884 1.00 0.00 ATOM 1132 2HG2 VAL 185 7.140 2.335 3.606 1.00 0.00 ATOM 1133 3HG2 VAL 185 6.909 1.563 5.176 1.00 0.00 ATOM 1134 QQG VAL 185 7.925 1.261 3.607 1.00 0.00 ATOM 1135 C VAL 185 7.139-2.040 2.666 1.00 0.00 ATOM 1136 O VAL 185 6.993-2.640 3.729 1.00 0.00 ATOM 1137 N CYS 186 7.555-2.646 1.561 1.00 0.00 ATOM 1138 H CYS 186 7.635-2.126 0.729 1.00 0.00 ATOM 1139 CA CYS 186 7.876-4.070 1.553 1.00 0.00 ATOM 1140 HA CYS 186 7.667-4.458 2.542 1.00 0.00 ATOM 1141 CB CYS 186 6.993-4.814 0.541 1.00 0.00 ATOM 1142 1HB CYS 186 5.973-4.805 0.897 1.00 0.00 ATOM 1143 2HB CYS 186 7.330-5.837 0.473 1.00 0.00 ATOM 1144 QB CYS 186 6.651-5.321 0.685 1.00 0.00 ATOM 1145 SG CYS 186 6.996-4.128-1.146 1.00 0.00 ATOM 1146 C CYS 186 9.354-4.297 1.247 1.00 0.00 ATOM 1147 O CYS 186 9.868-3.793 0.262 1.00 0.00 ATOM 1148 N CYS 187 10. 036-5. 064 2.087 1.00 0.00 ATOM 1149 H CYS 187 9.577-5.462 2.860 1.00 0.00 ATOM 1150 CA CYS 187 11.462-5.337 1.873 1.00 0.00 ATOM 1151 HA CYS 187 11.865-4.520 1.292 1.00 0.00 ATOM 1152 CB CYS 187 12.221-5.415 3.204 1.00 0.00 ATOM 1153 1HB CYS 187 13.010-6.148 3.114 1.00 0.00 ATOM 1154 2HB CYS 187 11.539-5.724 3.982 1.00 0.00 ATOM 1155 QB CYS 187 12.274-5.936 3.548 1.00 0.00 ATOM 1156 SG CYS 187 12.981-3.842 3.727 1.00 0.00 ATOM 1157 C CYS 187 11.661-6.626 1.099 1.00 0.00 ATOM 1158 O CYS 187 10.776-7.475 1.080 1.00 0.00 ATOM 1159 N PRO 188 12.824-6.783 0.439 1.00 0.00 ATOM 1160 CD PRO 188 13.929-5.804 0.398 1.00 0.00 ATOM 1161 CA PRO 188 13. 124-7. 984-0.345 1. 00 0. 00 ATOM 1162 HA PRO 188 12.398-8.130-1.133 1.00 0.00 ATOM 1163 CB PRO 188 14.497-7.694-0.964 1. 00 0. 00 ATOM 1164 1HB PRO 188 14.372-7.390-1.992 1.00 0.00 ATOM 1165 2HB PRO 188 15.104-8.588-0.922 1.00 0.00 ATOM 1166 QB PRO 188 14.738-7.989-1.457 1. 00 0.00

ATOM 1167 CG PRO 188 15.085-6.600-0.139 1.00 0.00 ATOM 1168 1HG PRO 188 15.715-5.975-0.755 1.00 0.00 ATOM 1169 2HG PRO 188 15.657-7.022 0.674 1.00 0.00 ATOM 1170 QG PRO 188 15.686-6.499-0.041 1.00 0.00 ATOM 1171 1HD PRO 188 13.694-4.982-0.264 1.00 0.00 ATOM 1172 2HD PRO 188 14.155-5.436 1.388 1.00 0.00 ATOM 1173 QD PRO 188 13.924-5.209 0.562 1.00 0.00 ATOM 1174 C PRO 188 13.181-9.245 0.516 1.00 0.00 ATOM 1175 O PRO 188 13.824-9.263 1.568 1.00 0.00 ATOM 1176 N LEU 189 12.501-10.283 0. 051 1.00 0.00 ATOM 1177 H LEU 189 12.014-10.188-0.795 1.00 0.00 ATOM 1178 CA LEU 189 12.452-11.561 0.740 1.00 0.00 ATOM 1179 HA LEU 189 13.120-11.514 1.587 1.00 0.00 ATOM 1180 CB LEU 189 11.027-11.841 1.230 1.00 0.00 ATOM 1181 1HB LEU 189 10.342-11.575 0.440 1.00 0.00 ATOM 1182 2HB LEU 189 10.832-11.208 2.083 1.00 0.00 ATOM 1183 QB LEU 189 10.587-11.392 1.261 1.00 0.00 ATOM 1184 CG LEU 189 10.747-13.291 1.634 1.00 0.00 ATOM 1185 HG LEU 189 11.534-13.922 1.242 1.00 0.00 ATOM 1186 QD1 LEU 189 10.737-13.468 3.503 1.00 0.00 ATOM 1187 QD2 LEU 189 9.116-13.874 0.907 1.00 0.00 ATOM 1188 CD1 LEU 189 10.739-13.434 3.146 1. 00 0.00 ATOM 1189 1HD1 LEU 189 10.402-12.510 3.593 1.00 0.00 ATOM 1190 2HD1 LEU 189 11.737-13.658 3.490 1.00 0.00 ATOM 1191 3HD1 LEU 189 10.072-14.235 3.427 1.00 0.00 ATOM 1192 CD2 LEU 189 9.427-13.762 1.046 1.00 0.00 ATOM 1193 1HD2 LEU 189 9.148-14.701 1.500 1.00 0.00 ATOM 1194 2HD2 LEU 189 9.537-13.895-0.020 1.00 0.00 ATOM 1195 3HD2 LEU 189 8.663-13.026 1.241 1.00 0.00 ATOM 1196 QQD LEU 189 9.926-13.671 2.205 1.00 0.00 ATOM 1197 C LEU 189 12.912-12.671-0.201 1.00 0.00 ATOM 1198 OT1 LEU 189 12.615-12.575-1.412 1.00 0.00 ATOM 1199 OT2 LEU 189 13.569-13.620 0.275 1.00 0.00 TER ENDMDL MODEL 16 ATOM 1 N SER 124 14.174 16.644-2.204 1.00 0.00 ATOM 2 CA SER 124 14.659 15.852-1.044 1.00 0.00 ATOM 3 HA SER 124 15.353 15.102-1.393 1.00 0.00 ATOM 4 CB SER 124 15.371 16.808-0.090 1.00 0.00 ATOM 5 1HB SER 124 16.303 16.366 0.231 1.00 0.00 ATOM 6 2HB SER 124 14.742 16.991 0.771 1.00 0.00 ATOM 7 QB SER 124 15.522 16.679 0.501 1.00 0.00 ATOM 8 OG SER 124 15.646 18.045-0.735 1.00 0.00 ATOM 9 HG SER 124 16.020 18.666-0.097 1.00 0.00 ATOM 10 C SER 124 13.489 15.176-0.354 1.00 0. 00 ATOM 11 O SER 124 13.359 15.208 0.870 1.00 0.00 ATOM 12 1HT SER 124 14.557 16.259-3.089 1.00 0.00 ATOM 13 2HT SER 124 14.478 17.633-2.106 1.00 0. 00 ATOM 14 3HT SER 124 13.129 16.614-2.247 1.00 0.00 ATOM 15 N ASP 125 12.631 14.591-1.166 1.00 0.00 ATOM 16 H ASP 125 12.792 14. 625-2.133 1.00 0.00 ATOM 17 CA ASP 125 11.439 13.922-0.694 1.00 0.00 ATOM 18 HA ASP 125 11.291 14.188 0.342 1.00 0.00 ATOM 19 CB ASP 125 10.234 14.392-1.515 1.00 0.00 ATOM 20 1HB ASP 125 9.637 15.065-0.918 1.00 0.00 ATOM 21 2HB ASP 125 9.637 13.535-1.791 1.00 0.00 ATOM 22 QB ASP 125 9.637 14. 300-1.355 1.00 0.00 ATOM 23 CG ASP 125 10.648 15.115-2.786 1.00 0.00 ATOM 24 OD1 ASP 125 10.421 14. 565-3.877 1.00 0.00 ATOM 25 OD2 ASP 125 11.229 16.225-2.686 1.00 0.00 ATOM 26 C ASP 125 11.607 12.416-0. 807 1.00 0.00 ATOM 27 0 ASP 125 12.447 11.935-1.568 1.00 0.00 ATOM 28 N ALA 126 10.814 11.675-0.048 1.00 0.00 ATOM 29 H ALA 126 10.166 12.114 0.540 1.00 0.00 ATOM 30 CA ALA 126 10.888 10.222-0. 068 1.00 0.00 ATOM 31 HA ALA 126 11.400 9.927-0.974 1.00 0.00 ATOM 32 QB ALA 126 11.883 9.590 1.398 1. 00 0. 00 ATOM 33 CB ALA 126 11.694 9.712 1.118 1. 00 0. 00 ATOM 34 1HB ALA 126 11.044 9.158 1.781 1.00 0. 00 ATOM 35 2HB ALA 126 12.124 10.547 1.649 1. 00 0. 00 ATOM 36 3HB ALA 126 12.483 9.064 0.765 1. 00 0. 00

ATOM 37 C ALA 126 9.498 9.605-0.063 1.00 0.00 ATOM 38 O ALA 126 9.026 9.121 0.964 1.00 0.00 ATOM 39 N LEU 127 8.847 9.622-1.216 1.00 0.00 ATOM 40 H LEU 127 9.275 10.021-2.001 1.00 0.00 ATOM 41 CA LEU 127 7.510 9.060-1.346 1.00 0.00 ATOM 42 HA LEU 127 7.062 9.035-0.366 1.00 0.00 ATOM 43 CB LEU 127 6.657 9.934-2.269 1.00 0.00 ATOM 44 1HB LEU 127 6.791 9.582-3.281 1.00 0.00 ATOM 45 2HB LEU 127 7.020 10.949-2.207 1.00 0.00 ATOM 46 QB LEU 127 6.905 10.266-2.744 1.00 0.00 ATOM 47 CG LEU 127 5.158 9.939-1.962 1.00 0.00 ATOM 48 HG LEU 127 4.870 8.967-1.585 1.00 0.00 ATOM 49 QD1 LEU 127 4.754 11.215-0.643 1.00 0.00 ATOM 50 QD2 LEU 127 4.167 10.275-3.524 1.00 0.00 ATOM 51 CD1 LEU 127 4.832 10.971-0.895 1.00 0.00 ATOM 52 1HD1 LEU 127 5.592 11.738-0.890 1.00 0.00 ATOM 53 2HD1 LEU 127 4.798 10.490 0.072 1.00 0.00 ATOM 54 3HD1 LEU 127 3.872 11.417-1.109 1.00 0.00 ATOM 55 CD2 LEU 127 4.358 10.210-3.225 1. 00 0.00 ATOM 56 1HD2 LEU 127 4.838 10.992-3.795 1.00 0.00 ATOM 57 2HD2 LEU 127 3.359 10.522-2.957 1.00 0.00 ATOM 58 3HD2 LEU 127 4.306 9.310-3.819 1.00 0.00 ATOM 59 QQD LEU 127 4.460 10.745-2.083 1.00 0.00 ATOM 60 C LEU 127 7.580 7.640-1.898 1.00 0.00 ATOM 61 O LEU 127 6.565 7.060-2.287 1.00 0.00 ATOM 62 N LEU 128 8.784 7.086-1.936 1.00 0.00 ATOM 63 H LEU 128 9.554 7.595-1.615 1.00 0.00 ATOM 64 CA LEU 128 8.985 5.742-2.446 1.00 0.00 ATOM 65 HA LEU 128 8.039 5.227-2.404 1.00 0.00 ATOM 66 CB LEU 128 9.460 5.802-3.903 1.00 0.00 ATOM 67 1HB LEU 128 10.540 5.809-3.905 1.00 0.00 ATOM 68 2HB LEU 128 9.111 6.729-4.333 1.00 0.00 ATOM 69 QB LEU 128 9.825 6.269-4.119 1.00 0.00 ATOM 70 CG LEU 128 8.987 4.649-4.794 1.00 0.00 ATOM 71 HG LEU 128 8.637 3.836-4.172 1.00 0.00 ATOM 72 QD1 LEU 128 7.553 5.203-5.876 1.00 0.00 ATOM 73 QD2 LEU 128 10.397 4.012-5.862 1.00 0.00 ATOM 74 CD1 LEU 128 7.827 5.097-5.668 1.00 0.00 ATOM 75 1HD1 LEU 128 7.340 4.231-6.091 1.00 0.00 ATOM 76 2HD1 LEU 128 8.199 5.725-6.465 1.00 0.00 ATOM 77 3HD1 LEU 128 7.120 5.653-5.071 1.00 0.00 ATOM 78 CD2 LEU 128 10.128 4.134-5.656 1.00 0.00 ATOM 79 1HD2 LEU 128 10.431 3.158-5.308 1.00 0.00 ATOM 80 2HD2 LEU 128 10.963 4.815-5.593 1.00 0.00 ATOM 81 3HD2 LEU 128 9.798 4.063-6.683 1.00 0.00 ATOM 82 QQD LEU 128 8.975 4.608-5.869 1.00 0.00 ATOM 83 C LEU 128 9.990 4.993-1.572 1.00 0.00 ATOM 84 O LEU 128 10.102 5.275-0.381 1.00 0.00 ATOM 85 N VAL 129 10.697 4.038-2.174 1.00 0.00 ATOM 86 H VAL 129 10.535 3.874-3.126 1.00 0.00 ATOM 87 CA VAL 129 11. 695 3. 212-1. 480 1.00 0.00 ATOM 88 HA VAL 129 11. 167 2.504-0.862 1.00 0.00 ATOM 89 CB VAL 129 12.543 2.418-2.501 1.00 0.00 ATOM 90 HB VAL 129 13.133 3.124-3.069 1.00 0.00 ATOM 91 QG1 VAL 129 13.726 1.239-1.636 1.00 0.00 ATOM 92 QG2 VAL 129 11.437 1.482-3.699 1.00 0.00 ATOM 93 CG1 VAL 129 13.500 1.464-1.802 1.00 0.00 ATOM 94 1HG1 VAL 129 14.321 2.024-1.378 1.00 0.00 ATOM 95 2HG1 VAL 129 13.882 0. 750-2.516 1.00 0.00 ATOM 96 3HG1 VAL 129 12.977 0.941-1.014 1.00 0.00 ATOM 97 CG2 VAL 129 11.649 1.660-3.469 1.00 0.00 ATOM 98 1HG2 VAL 129 11.825 0.600-3.366 1.00 0.00 ATOM 99 2HG2 VAL 129 11.874 1.966-4.480 1.00 0.00 ATOM 100 3HG2 VAL 129 10.614 1.878-3.249 1.00 0.00 ATOM 101 QQG VAL 129 12.582 1.360-2.667 1.00 0.00 ATOM 102 C VAL 129 12.636 4.036-0.591 1.00 0.00 ATOM 103 O VAL 129 13.443 4.819-1.088 1.00 0.00 ATOM 104 N PRO 130 12.533 3.861 0.744 1.00 0.00 ATOM 105 CD PRO 130 11.596 2.967 1.418 1.00 0.00 ATOM 106 CA PRO 130 13.363 4.568 1.715 1.00 0.00 ATOM 107 HA PRO 130 13.525 5.587 1.426 1.00 0.00 ATOM 108 CB PRO 130 12.525 4.527 3.008 1.00 0.00

ATOM 109 1HB PRO 130 12.252 5.535 3.287 1.00 0.00 ATOM 110 2HB PRO 130 13.110 4.083 3.799 1.00 0.00 ATOM 111 QB PRO 130 12.681 4.809 3.543 1.00 0.00 ATOM 112 CG PRO 130 11.309 3.702 2.699 1.00 0.00 ATOM 113 1HG PRO 130 10.452 4.349 2.573 1.00 0.00 ATOM 114 2HG PRO 130 11.130 2.999 3.499 1.00 0.00 ATOM 115 QG PRO 130 10.791 3.674 3.036 1.00 0.00 ATOM 116 1HD PRO 130 10.692 2.847 0.838 1.00 0.00 ATOM 117 2HD PRO 130 12.051 2.007 1.619 1.00 0.00 ATOM 118 QD PRO 130 11.371 2.427 1.228 1.00 0. 00 ATOM 119 C PRO 130 14.718 3.893 1.928 1.00 0.00 ATOM 120 O PRO 130 15.679 4.166 1.214 1.00 0.00 ATOM 121 N ASP 131 14.776 3.023 2.927 1.00 0.00 ATOM 122 H ASP 131 13.973 2.870 3.454 1.00 0.00 ATOM 123 CA ASP 131 16.005 2.302 3.265 1.00 0.00 ATOM 124 HA ASP 131 16.839 2.956 3.053 1.00 0.00 ATOM 125 CB ASP 131 16.016 1.955 4.764 1.00 0.00 ATOM 126 1HB ASP 131 15.152 1.351 4.993 1.00 0.00 ATOM 127 2HB ASP 131 15.973 2.868 5.336 1.00 0.00 ATOM 128 QB ASP 131 15.562 2.110 5.164 1.00 0.00 ATOM 129 CG ASP 131 17.259 1.193 5.185 1.00 0.00 ATOM 130 OD1 ASP 131 18.366 1.752 5.077 1.00 0.00 ATOM 131 OD2 ASP 131 17.117 0.027 5.613 1.00 0.00 ATOM 132 C ASP 131 16.157 1.030 2.421 1.00 0.00 ATOM 133 O ASP 131 16.569 1.084 1.264 1.00 0.00 ATOM 134 N LYS+ 132 15.836-0.116 3.012 1.00 0.00 ATOM 135 H LYS+ 132 15.531-0.101 3.943 1.00 0.00 ATOM 136 CA LYS+ 132 15.956-1.394 2.321 1.00 0.00 ATOM 137 HA LYS+ 132 16.532-1.230 1.423 1.00 0.00 ATOM 138 CB LYS+ 132 16.689-2.400 3.204 1.00 0.00 ATOM 139 1HB LYS+ 132 16.494-3.396 2.836 1.00 0.00 ATOM 140 2HB LYS+ 132 16.313-2.317 4.215 1.00 0.00 ATOM 141 QB LYS+ 132 16.403-2.856 3.525 1.00 0.00 ATOM 142 CG LYS+ 132 18.190-2.183 3.232 1.00 0.00 ATOM 143 1HG LYS+ 132 18.626-2.822 3.983 1.00 0.00 ATOM 144 2HG LYS+ 132 18.387-1.147 3.478 1.00 0.00 ATOM 145 QG LYS+ 132 18.506-1.984 3.730 1.00 0.00 ATOM 146 CD LYS+ 132 18.813-2.497 1.883 1.00 0.00 ATOM 147 1HD LYS+ 132 19.270-1.598 1.492 1.00 0.00 ATOM 148 2HD LYS+ 132 18.033-2.826 1.209 1.00 0.00 ATOM 149 QD LYS+ 132 18.651-2.212 1.350 1.00 0.00 ATOM 150 CE LYS+ 132 19.870-3.587 1.989 1.00 0.00 ATOM 151 1HE LYS+ 132 20.839-3.150 1.789 1.00 0. 00 ATOM 152 2HE LYS+ 132 19.660-4.347 1.251 1.00 0.00 ATOM 153 QE LYS+ 132 20.249-3.748 1.520 1.00 0.00 ATOM 154 NZ LYS+ 132 19.890-4.216 3.343 1.00 0.00 ATOM 155 1HZ LYS+ 132 20.393-5.126 3.310 1.00 0.00 ATOM 156 2HZ LYS+ 132 18.918-4.382 3.674 1.00 0. 00 ATOM 157 3HZ LYS+ 132 20.371-3.588 4.022 1.00 0.00 ATOM 158 QZ LYS+ 132 19.894-4.365 3.668 1.00 0.00 ATOM 159 C LYS+ 132 14.594-1.945 1.935 1.00 0.00 ATOM 160 O LYS+ 132 14.490-2.941 1.222 1.00 0.00 ATOM 161 N CYS 133 13.552-1.292 2.407 1.00 0.00 ATOM 162 H CYS 133 13.700-0.505 2.967 1.00 0.00 ATOM 163 CA CYS 133 12.195-1.709 2.108 1.00 0.00 ATOM 164 HA CYS 133 12.211-2.763 1.878 1.00 0.00 ATOM 165 CB CYS 133 11.283-1.466 3.310 1.00 0.00 ATOM 166 1HB CYS 133 10.297-1.226 2.949 1.00 0.00 ATOM 167 2HB CYS 133 11.662-0.628 3.871 1.00 0.00 ATOM 168 QB CYS 133 10.979-0.927 3.410 1.00 0.00 ATOM 169 SG CYS 133 11.122-2.868 4.465 1.00 0.00 ATOM 170 C CYS 133 11.671-0.942 0.900 1.00 0.00 ATOM 171 O CYS 133 12.126 0.158 0.618 1.00 0.00 ATOM 172 N LYS+ 134 10.714-1.521 0.196 1.00 0.00 ATOM 173 H LYS+ 134 10.380-2.400 0.474 1.00 0.00 ATOM 174 CA LYS+ 134 10.135-0.885-0.977 1.00 0.00 ATOM 175 HA LYS+ 134 10.837-0.147-1. 336 1.00 0.00 ATOM 176 CB LYS+ 134 9.887-1.922-2.077 1.00 0.00 ATOM 177 1HB LYS+ 134 9.127-2.611-1. 738 1.00 0.00 ATOM 178 2HB LYS+ 134 10. 802-2.468-2. 252 1.00 0.00 ATOM 179 QB LYS+ 134 9.964-2.539-1. 995 1.00 0. 00 ATOM 180 CG LYS+ 134 9. 430-1.320-3.398 1. 00 0.00

ATOM 181 1HG LYS+ 134 9.956-0.388-3.556 1.00 0.00 ATOM 182 2HG LYS+ 134 8.368-1.131-3.349 1.00 0.00 ATOM 183 QG LYS+ 134 9.162-0.759-3.453 1.00 0.00 ATOM 184 CD LYS+ 134 9.715-2.251-4.567 1.00 0.00 ATOM 185 1HD LYS+ 134 10.256-3.113-4.206 1.00 0.00 ATOM 186 2HD LYS+ 134 10.319-1.725-5.293 1.00 0.00 ATOM 187 QD LYS+ 134 10.287-2.419-4.750 1.00 0.00 ATOM 188 CE LYS+ 134 8.431-2.715-5.241 1.00 0.00 ATOM 189 1HE LYS+ 134 8.666-3.529-5.912 1.00 0.00 ATOM 190 2HE LYS+ 134 8.020-1.892-5.808 1.00 0.00 ATOM 191 QE LYS+ 134 8.343-2.710-5.860 1.00 0.00 ATOM 192 NZ LYS+ 134 7.415-3.178-4.252 1.00 0.00 ATOM 193 1HZ LYS+ 134 7.881-3.510-3.383 1.00 0.00 ATOM 194 2HZ LYS+ 134 6.854-3.958-4.649 1.00 0.00 ATOM 195 3HZ LYS+ 134 6.771-2.396-4.007 1.00 0.00 ATOM 196 QZ LYS+ 134 7.168-3.288-4.013 1.00 0.00 ATOM 197 C LYS+ 134 8.834-0.192-0.607 1.00 0.00 ATOM 198 O LYS+ 134 7.843-0.851-0.310 1.00 0.00 ATOM 199 N PHE 135 8.848 1.131-0.619 1.00 0.00 ATOM 200 H PHE 135 9.674 1.598-0.862 1.00 0.00 ATOM 201 CA PHE 135 7.667 1.911-0.273 1.00 0.00 ATOM 202 HA PHE 135 7.041 1.304 0.365 1.00 0.00 ATOM 203 CB PHE 135 8.084 3.172 0.488 1.00 0.00 ATOM 204 1HB PHE 135 8.677 3.794-0.169 1.00 0.00 ATOM 205 2HB PHE 135 8.687 2.886 1.335 1.00 0.00 ATOM 206 QB PHE 135 8.682 3.340 0.583 1.00 0.00 ATOM 207 QD PHE 135 6.823 4.102 1.063 1.00 0.00 ATOM 208 QE PHE 135 4.984 5.483 1.931 1.00 0.00 ATOM 209 QR PHE 135 5.534 5.069 1.672 1.00 0.00 ATOM 210 CG PHE 135 6.947 4.008 1.004 1.00 0.00 ATOM 211 CD1 PHE 135 5.812 3.419 1.533 1.00 0.00 ATOM 212 1HD PHE 135 5.737 2.342 1.564 1.00 0.00 ATOM 213 CE1 PHE 135 4.779 4.192 2.022 1.00 0.00 ATOM 214 1HE PHE 135 3.898 3.720 2.434 1.00 0.00 ATOM 215 CZ PHE 135 4.870 5.569 1.985 1.00 0.00 ATOM 216 HZ PHE 135 4.060 6.175 2.369 1.00 0.00 ATOM 217 CE2 PHE 135 5.995 6.169 1.459 1.00 0.00 ATOM 218 2HE PHE 135 6.070 7.246 1.429 1.00 0.00 ATOM 219 CD2 PHE 135 7.027 5.390 0.974 1.00 0.00 ATOM 220 2HD PHE 135 7.909 5.861 0.563 1.00 0.00 ATOM 221 C PHE 135 6.885 2.276-1.526 1.00 0.00 ATOM 222 O PHE 135 7.428 2.860-2.464 1.00 0.00 ATOM 223 N LEU 136 5.612 1.913-1.536 1.00 0.00 ATOM 224 H LEU 136 5.245 1.439-0.756 1.00 0.00 ATOM 225 CA LEU 136 4.742 2.184-2.666 1.00 0.00 ATOM 226 HA LEU 136 5.312 2.733-3.401 1.00 0.00 ATOM 227 CB LEU 136 4.244 0.877-3.293 1.00 0.00 ATOM 228 1HB LEU 136 3.657 1.125-4.164 1.00 0.00 ATOM 229 2HB LEU 136 3.598 0.386-2.577 1.00 0.00 ATOM 230 QB LEU 136 3.627 0.756-3.371 1.00 0.00 ATOM 231 CG LEU 136 5.335-0.111-3.714 1.00 0.00 ATOM 232 HG LEU 136 6.250 0.432-3.901 1.00 0.00 ATOM 233 QD1 LEU 136 5.658-1.349-2.339 1.00 0.00 ATOM 234 QD2 LEU 136 4.840-0.999-5.295 1.00 0.00 ATOM 235 CD1 LEU 136 5.597-1.113-2.604 1.00 0.00 ATOM 236 1HD1 LEU 136 5.211-2.080-2.891 1.00 0.00 ATOM 237 2HD1 LEU 136 5.104-0.783-1.699 1.00 0.00 ATOM 238 3HD1 LEU 136 6.660-1.185-2.425 1.00 0.00 ATOM 239 CD2 LEU 136 4.936-0.829-4.992 1.00 0.00 ATOM 240 1HD2 LEU 136 5.746-0.774-5.705 1.00 0.00 ATOM 241 2HD2 LEU 136 4.057-0.360-5.409 1.00 0.00 ATOM 242 3HD2 LEU 136 4.719-1.864-4.770 1.00 0.00 ATOM 243 QQD LEU 136 5.249-1.174-3.817 1.00 0.00 ATOM 244 C LEU 136 3.550 3.025-2.234 1.00 0.00 ATOM 245 0 LEU 136 2.490 2.492-1.915 1.00 0.00 ATOM 246 N HIS+ 137 3.723 4.338-2.236 1.00 0.00 ATOM 247 H HIS+ 137 4.589 4.709-2.508 1.00 0.00 ATOM 248 CA HIS+ 137 2.648 5.243-1.859 1.00 0.00 ATOM 249 HA HIS+ 137 1.962 4.698-1.220 1.00 0.00 ATOM 250 CB HIS+ 137 3.207 6.456-1.093 1.00 0.00 ATOM 251 1HB HIS+ 137 4.025 6.881-1.658 1.00 0.00 ATOM 252 2HB HIS+ 137 3.577 6.126-0.133 1.00 0.00

ATOM 253 QB HIS+ 137 3.801 6.504-0.896 1.00 0.00 ATOM 254 CG HIS+ 137 2.203 7.548-0.844 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.771 8.411-1.828 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.535 7.901 0.279 1.00 0.00 ATOM 257 1HD HIS+ 137 2.070 8.407-2.765 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.880 9.244-1.323 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.715 8.957-0.044 1.00 0.00 ATOM 260 2HD HIS+ 137 1.629 7.438 1.255 1.00 0.00 ATOM 261 1HE HIS+ 137 0.363 10.022-1.866 1.00 0.00 ATOM 262 2HE HIS+ 137-0.059 9.248 0.492 1.00 0.00 ATOM 263 C HIS+ 137 1.914 5.698-3.115 1.00 0.00 ATOM 264 O HIS+ 137 2.438 6. 501-3.890 1.00 0.00 ATOM 265 N GLN 138 0.714 5.177-3.328 1.00 0.00 ATOM 266 H GLN 138 0.346 4.531-2.682 1.00 0.00 ATOM 267 CA GLN 138-0.068 5.533-4.506 1.00 0.00 ATOM 268 HA GLN 138 0.381 6.412-4.945 1.00 0.00 ATOM 269 CB GLN 138-0.043 4.394-5.536 1.00 0.00 ATOM 270 1HB GLN 138-0.143 4.819-6.524 1.00 0.00 ATOM 271 2HB GLN 138-0.884 3.742-5.351 1.00 0.00 ATOM 272 QB GLN 138-0.514 4.281-5.938 1.00 0.00 ATOM 273 CG GLN 138 1.226 3.551-5.508 1.00 0.00 ATOM 274 1HG GLN 138 0.983 2.546-5.824 1.00 0.00 ATOM 275 2HG GLN 138 1.606 3.526-4.498 1.00 0.00 ATOM 276 QG GLN 138 1.294 3.036-5.161 1.00 0.00 ATOM 277 CD GLN 138 2.308 4.097-6.420 1.00 0.00 ATOM 278 OE1 GLN 138 2.052 4.416-7.578 1.00 0.00 ATOM 279 NE2 GLN 138 3.526 4.209-5.902 1.00 0.00 ATOM 280 1HE2 GLN 138 3.663 3.937-4.972 1.00 0.00 ATOM 281 2HE2 GLN 138 4.239 4.563-6.473 1.00 0.00 ATOM 282 QE2 GLN 138 3.951 4.250-5.723 1.00 0.00 ATOM 283 C GLN 138-1.512 5.850-4.134 1.00 0.00 ATOM 284 O GLN 138-2.159 5.085-3.416 1.00 0.00 ATOM 285 N GLU 139-2.013 6.969-4.640 1.00 0.00 ATOM 286 H GLU 139-1.451 7.527-5.215 1.00 0.00 ATOM 287 CA GLU 139-3.386 7.381-4.379 1.00 0.00 ATOM 288 HA GLU 139-3.717 6.889-3.474 1.00 0.00 ATOM 289 CB GLU 139-3.459 8.897-4.182 1.00 0.00 ATOM 290 1HB GLU 139-4.444 9.153-3.819 1.00 0.00 ATOM 291 2HB GLU 139-3.299 9.381-5.133 1.00 0.00 ATOM 292 QB GLU 139-3.872 9.267-4.476 1.00 0.00 ATOM 293 CG GLU 139-2.436 9.431-3.192 1.00 0.00 ATOM 294 1HG GLU 139-2.270 10.479-3.393 1.00 0.00 ATOM 295 2HG GLU 139-1.511 8.890-3.321 1.00 0.00 ATOM 296 QG GLU 139-1.891 9.685-3.357 1.00 0.00 ATOM 297 CD GLU 139-2.885 9.281-1.755 1.00 0.00 ATOM 298 OE1 GLU 139-3.826 8.497-1.506 1.00 0.00 ATOM 299 OE2 GLU 139-2.297 9.944-0.878 1.00 0.00 ATOM 300 C GLU 139-4.286 6.957-5.534 1.00 0.00 ATOM 301 O GLU 139-4.239 7.540-6.619 1.00 0.00 ATOM 302 N ARG+ 140-5.096 5.935-5.304 1.00 0.00 ATOM 303 H ARG+ 140-5.089 5.506-4.420 1.00 0.00 ATOM 304 CA ARG+ 140-5.997 5. 430-6. 330 1.00 0.00 ATOM 305 HA ARG+ 140-5.638 5.780-7.287 1.00 0.00 ATOM 306 CB ARG+ 140-6.000 3.895-6.326 1.00 0.00 ATOM 307 1HB ARG+ 140-6.552 3.555-5.460 1.00 0.00 ATOM 308 2HB ARG+ 140-4.982 3.545-6.250 1.00 0.00 ATOM 309 QB ARG+ 140-5. 767 3.550-5.855 1.00 0.00 ATOM 310 CG ARG+ 140-6. 628 3.272-7.563 1.00 0.00 ATOM 311 1HG ARG+ 140-7.641 3.637-7.662 1.00 0.00 ATOM 312 2HG ARG+ 140-6.642 2.199-7.445 1.00 0.00 ATOM 313 QG ARG+ 140-7.142 2.918-7.554 1. 00 0. 00 ATOM 314 CD ARG+ 140-5.854 3.620-8.824 1.00 0.00 ATOM 315 1HD ARG+ 140-4.845 3.893-8.549 1.00 0.00 ATOM 316 2HD ARG+ 140-6.336 4.464-9.302 1.00 0.00 ATOM 317 QD ARG+ 140-5.591 4.179-8.926 1.00 0.00 ATOM 318 NE ARG+ 140-5.807 2.503-9.768 1.00 0.00 ATOM 319 HE ARG+ 140-5.437 1.654-9.443 1.00 0.00 ATOM 320 CZ ARG+ 140-6.223 2.587-11.034 1.00 0. 00 ATOM 321 NH1 ARG+ 140-6. 767 3.710-11.482 1. 00 0.00 ATOM 322 1HH1 ARG+ 140-6.873 4.505-10.866 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.089 3. 777-12. 426 1.00 0. 00 ATOM 324 QH1 ARG+ 140-6.981 4.141-11.646 1.00 0.00

ATOM 325 NH2 ARG+ 140-6.115 1.538-11.842 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.720 0.682-11.506 1.00 0.00 ATOM 327 2HH2 ARG+ 140-6.431 1.600-12.790 1.00 0.00 ATOM 328 QH2 ARG+ 140-6.076 1.141-12.148 1.00 0.00 ATOM 329 C ARG+ 140-7.409 5.959-6.111 1.00 0.00 ATOM 330 O ARG+ 140-8.244 5.292-5.499 1.00 0.00 ATOM 331 N MET 141-7.678 7.155-6.627 1.00 0.00 ATOM 332 H MET 141-6.973 7.629-7.115 1.00 0.00 ATOM 333 CA MET 141-8.998 7.778-6.501 1.00 0.00 ATOM 334 HA MET 141-9.327 7.655-5.481 1.00 0.00 ATOM 335 CB MET 141-8.895 9.276-6.821 1.00 0.00 ATOM 336 1HB MET 141-8.852 9.396-7.894 1.00 0.00 ATOM 337 2HB MET 141-7. 983 9.661-6.389 1.00 0.00 ATOM 338 QB MET 141-8. 418 9.529-7.142 1.00 0.00 ATOM 339 CG MET 141-10.056 10.110-6.297 1.00 0.00 ATOM 340 1HG MET 141-10.980 9.664-6.634 1.00 0.00 ATOM 341 2HG MET 141-9.974 11.109-6.701 1.00 0.00 ATOM 342 QG MET 141-10.477 10.387-6.668 1.00 0.00 ATOM 343 SD MET 141-10.085 10.219-4.499 1.00 0.00 ATOM 344 QE MET 141-11.282 11.985-4.211 1.00 0.00 ATOM 345 CE MET 141-11.082 11.688-4.260 1.00 0.00 ATOM 346 1HE MET 141-11.721 11.836-5.118 1.00 0.00 ATOM 347 2HE MET 141-10. 435 12.546-4.140 1.00 0.00 ATOM 348 3HE MET 141-11.689 11.571-3.374 1.00 0.00 ATOM 349 C MET 141-10.011 7.105-7.436 1.00 0.00 ATOM 350 O MET 141-10.924 7.750-7.958 1.00 0.00 ATOM 351 N ASP 142-9.841 5.807-7.641 1.00 0.00 ATOM 352 H ASP 142-9.097 5.352-7.198 1.00 0.00 ATOM 353 CA ASP 142-10.709 5.037-8.505 1.00 0.00 ATOM 354 HA ASP 142-11.400 5.714-8.984 1.00 0.00 ATOM 355 CB ASP 142-9.880 4.330-9.574 1.00 0.00 ATOM 356 1HB ASP 142-10.545 3.838-10.257 1.00 0.00 ATOM 357 2HB ASP 142-9.251 3.593-9.102 1.00 0.00 ATOM 358 QB ASP 142-9.898 3.716-9.680 1.00 0.00 ATOM 359 CG ASP 142-8.997 5.273-10.360 1.00 0.00 ATOM 360 OD1 ASP 142-7.902 5.615-9.862 1.00 0.00 ATOM 361 OD2 ASP 142-9.374 5.639-11.486 1.00 0.00 ATOM 362 C ASP 142-11.486 3.993-7.716 1.00 0.00 ATOM 363 O ASP 142-12.712 3.916-7.803 1.00 0.00 ATOM 364 N VAL 143-10.768 3.178-6.953 1.00 0.00 ATOM 365 H VAL 143-9.794 3.279-6.928 1.00 0.00 ATOM 366 CA VAL 143-11.398 2.119-6.174 1.00 0.00 ATOM 367 HA VAL 143-12.327 1.864-6.665 1.00 0.00 ATOM 368 CB VAL 143-10.513 0.852-6.133 1.00 0.00 ATOM 369 HB VAL 143-9.911 0.886-5.233 1.00 0.00 ATOM 370 QG1 VAL 143-11.573-0.702-6.067 1.00 0.00 ATOM 371 QG2 VAL 143-9.354 0.789-7.614 1.00 0.00 ATOM 372 CG1 VAL 143-11.371-0.404-6.079 1.00 0.00 ATOM 373 1HG1 VAL 143-12.278-0.246-6.642 1.00 0.00 ATOM 374 2HG1 VAL 143-11.618-0.630-5.052 1.00 0.00 ATOM 375 3HG1 VAL 143-10.822-1.231-6.507 1.00 0.00 ATOM 376 CG2 VAL 143-9.576 0.801-7.331 1.00 0.00 ATOM 377 1HG2 VAL 143-9.888 1.531-8.064 1.00 0.00 ATOM 378 2HG2 VAL 143-9.606-0.186-7.769 1.00 0.00 ATOM 379 3HG2 VAL 143-8.568 1.021-7.009 1.00 0.00 ATOM 380 QQG VAL 143-10.464 0.044-6.841 1.00 0.00 ATOM 381 C VAL 143-11.712 2.587-4.750 1.00 0.00 ATOM 382 O VAL 143-11.202 3.609-4.294 1.00 0.00 ATOM 383 N CYS 144-12.584 1.849-4.070 1.00 0.00 ATOM 384 H CYS 144-12.973 1.058-4.499 1.00 0.00 ATOM 385 CA CYS 144-13.000 2.189-2.710 1.00 0.00 ATOM 386 HA CYS 144-12.198 2.740-2.227 1.00 0.00 ATOM 387 CB CYS 144-14.253 3.067-2.776 1.00 0.00 ATOM 388 1HB CYS 144-15.014 2.546-3.341 1.00 0.00 ATOM 389 2HB CYS 144-14.010 3.989-3.280 1.00 0.00 ATOM 390 QB CYS 144-14.512 3.268-3.311 1.00 0.00 ATOM 391 SG CYS 144-14.967 3.498-1.160 1.00 0.00 ATOM 392 C CYS 144-13.285 0.930-1.902 1.00 0.00 ATOM 393 O CYS 144-14.411 0.434-1.891 1.00 0.00 ATOM 394 N GLU 145-12.267 0.411-1.234 1.00 0.00 ATOM 395 H GLU 145-11.387 0.840-1.280 1.00 0.00 ATOM 396 CA GLU 145-12.427-0.794-0.443 1.00 0.00

ATOM 397 HA GLU 145-13.470-1.067-0.478 1.00 0.00 ATOM 398 CB GLU 145-11.613-1.928-1.045 1.00 0.00 ATOM 399 1HB GLU 145-11.382-2.641-0.271 1.00 0.00 ATOM 400 2HB GLU 145-10. 690-1.527-1.441 1.00 0.00 ATOM 401 QB GLU 145-11.036-2.084-0.856 1.00 0.00 ATOM 402 CG GLU 145-12.350-2.656-2.159 1.00 0.00 ATOM 403 1HG GLU 145-11.652-3.296-2.677 1.00 0.00 ATOM 404 2HG GLU 145-12.747-1.926-2.848 1.00 0.00 ATOM 405 QG GLU 145-12.200-2.611-2.763 1.00 0.00 ATOM 406 CD GLU 145-13.496-3.506-1.644 1.00 0.00 ATOM 407 OE1 GLU 145-13.970-3.251-0.514 1.00 0.00 ATOM 408 OE2 GLU 145-13.916-4.432-2.362 1.00 0.00 ATOM 409 C GLU 145-12.038-0.569 1.009 1.00 0.00 ATOM 410 O GLU 145-11.635 0.528 1.392 1.00 0.00 ATOM 411 N THR 146-12.189-1.614 1.811 1.00 0.00 ATOM 412 H THR 146-12.530-2.453 1.438 1.00 0.00 ATOM 413 CA THR 146-11.889-1.553 3.232 1.00 0.00 ATOM 414 HA THR 146-12.315-0.640 3.625 1.00 0.00 ATOM 415 CB THR 146-12.545-2.748 3.928 1.00 0.00 ATOM 416 HB THR 146-11.840-3.568 3.950 1.00 0.00 ATOM 417 QG2 THR 146-13.073-2.397 5.692 1.00 0.00 ATOM 418 OG1 THR 146-13.698-3.171 3.210 1.00 0.00 ATOM 419 1HG THR 146-13.896-4.087 3.433 1.00 0.00 ATOM 420 CG2 THR 146-12.971-2.467 5.351 1.00 0.00 ATOM 421 1HG2 THR 146-12.840-1.414 5.567 1.00 0. 00 ATOM 422 2HG2 THR 146-12.367-3.049 6.032 1.00 0.00 ATOM 423 3HG2 THR 146-14.010-2.730 5.478 1.00 0.00 ATOM 424 C THR 146-10.383-1.540 3.480 1.00 0.00 ATOM 425 O THR 146-9.597-1.893 2.597 1.00 0.00 ATOM 426 N HIS+ 147-9.993-1.139 4.689 1.00 0.00 ATOM 427 H HIS+ 147-10.678-0.874 5.344 1.00 0.00 ATOM 428 CA HIS+ 147-8.584-1.078 5.080 1.00 0.00 ATOM 429 HA HIS+ 147-8.097-0.337 4.464 1.00 0.00 ATOM 430 CB HIS+ 147-8.473-0.660 6.550 1.00 0.00 ATOM 431 1HB HIS+ 147-8.439-1.548 7.165 1.00 0.00 ATOM 432 2HB HIS+ 147-9.344-0.080 6.818 1.00 0.00 ATOM 433 QB HIS+ 147-8.892-0.814 6.991 1.00 0.00 ATOM 434 CG HIS+ 147-7.261 0.163 6.866 1.00 0. 00 ATOM 435 ND1 HIS+ 147-7.302 1.532 7.026 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.971-0.198 7.069 1.00 0.00 ATOM 437 1HD HIS+ 147-8.106 2.097 6.940 1.00 0.00 ATOM 438 CE1 HIS+ 147-6.092 1.977 7.315 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.265 0.948 7.348 1.00 0.00 ATOM 440 2HD HIS+ 147-5.568-1.202 7.009 1.00 0.00 ATOM 441 1HE HIS+ 147-5.825 3.010 7.496 1.00 0.00 ATOM 442 2HE HIS+ 147-4.334 0.982 7.659 1.00 0.00 ATOM 443 C HIS+ 147-7.897-2.427 4.876 1.00 0.00 ATOM 444 O HIS+ 147-6.713-2.491 4.547 1.00 0.00 ATOM 445 N LEU 148-8.649-3.503 5.072 1.00 0.00 ATOM 446 H LEU 148-9.588-3.389 5.329 1.00 0.00 ATOM 447 CA LEU 148-8.111-4.848 4.914 1.00 0.00 ATOM 448 HA LEU 148-7.148-4.877 5.402 1.00 0.00 ATOM 449 CB LEU 148-9.033-5.871 5.582 1.00 0.00 ATOM 450 1HB LEU 148-9.765'-6.192 4.857 1.00 0.00 ATOM 451 2HB LEU 148-9.547-5.383 6.398 1.00 0.00 ATOM 452 QB LEU 148-9.656-5.787 5.627 1.00 0.00 ATOM 453 CG LEU 148-8.328-7.112 6. 130 1.00 0.00 ATOM 454 HG LEU 148-7.261-6.942 6.125 1.00 0.00 ATOM 455 QD1 LEU 148-8.854-7.442 7.904 1.00 0.00 ATOM 456 QD2 LEU 148-8.686-8.608 5.049 1.00 0.00 ATOM 457 CD1 LEU 148-8.753-7.378 7.564 1.00 0.00 ATOM 458 1HD1 LEU 148-8.289-6.655 8.218 1.00 0.00 ATOM 459 2HD1 LEU 148-8.444-8.373 7.851 1.00 0.00 ATOM 460 3HD1 LEU 148-9.827-7.299 7.643 1.00 0.00 ATOM 461 CD2 LEU 148-8.617-8.321 5.256 1.00 0.00 ATOM 462 1HD2 LEU 148-8.317-9.220 5.775 1.00 0. 00 ATOM 463 2HD2 LEU 148-8.064-8.239 4.331 1.00 0.00 ATOM 464 3HD2 LEU 148-9.675-8.367 5.041 1.00 0.00 ATOM 465 QQD LEU 148-8.770-8.025 6.476 1.00 0.00 ATOM 466 C LEU 148-7.923-5.202 3.444 1.00 0.00 ATOM 467 O LEU 148-7.014-5.947 3.094 1.00 0.00 ATOM 468 N HIS+ 149-8.782-4.663 2.586 1. 00 0. 00

ATOM 469 H HIS+ 149-9.485-4.069 2.919 1.00 0.00 ATOM 470 CA HIS+ 149-8.692-4.934 1.156 1.00 0.00 ATOM 471 HA HIS+ 149-8.681-6.007 1.028 1.00 0.00 ATOM 472 CB HIS+ 149-9. 895-4.364 0.418 1.00 0.00 ATOM 473 1HB HIS+ 149-9.550-3.759-0.409 1.00 0.00 ATOM 474 2HB HIS+ 149-10.467-3.747 1.093 1.00 0.00 ATOM 475 QB HIS+ 149-10.009-3.753 0.342 1.00 0.00 ATOM 476 CG HIS+ 149-10.807-5.416-0.132 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.570-6.243 0. 662 1.00 0.00 ATOM 478 CD2 HIS+ 149-11.097-5.751-1.409 1.00 0.00 ATOM 479 1HD HIS+ 149-11.579-6.250 1.641 1.00 0.00 ATOM 480 CE1 HIS+ 149-12.292-7.040-0.106 1.00 0.00 ATOM 481 NE2 HIS+ 149-12.028-6.761-1.372 1.00 0.00 ATOM 482 2HD HIS+ 149-10.678-5.300-2.299 1.00 0.00 ATOM 483 1HE HIS+ 149-12.986-7.792 0.242 1.00 0.00 ATOM 484 2HE HIS+ 149-12.622-6.990-2.121 1.00 0.00 ATOM 485 C HIS+ 149-7. 404-4.370 0.583 1.00 0.00 ATOM 486 O HIS+ 149-6.621-5.105-0.007 1.00 0.00 ATOM 487 N TRP 150-7.174-3.072 0.777 1.00 0.00 ATOM 488 H TRP 150-7.831-2.533 1.268 1 : 00 0.00 ATOM 489 CA TRP 150-5.947-2.441 0.287 1.00 0.00 ATOM 490 HA TRP 150-5. 890-2.593-0.782 1.00 0.00 ATOM 491 CB TRP 150-5.916-0.945 0.600 1.00 0.00 ATOM 492 1HB TRP 150-4.970-0.542 0.264 1.00 0.00 ATOM 493 2HB TRP 150-5.992-0.811 1.668 1.00 0.00 ATOM 494 QB TRP 150-5.481-0.676 0.966 1.00 0.00 ATOM 495 CG TRP 150-7. 008-0.144-0.037 1.00 0.00 ATOM 496 CD1 TRP 150-7. 510 1.038 0.418 1.00 0.00 ATOM 497 CD2 TRP 150-7.726-0.447-1.239 1.00 0.00 ATOM 498 CE3 TRP 150-7.683-1.495-2.163 1.00 0.00 ATOM 499 CE2 TRP 150-8. 646 0.597-1.443 1.00 0.00 ATOM 500 NE1 TRP 150-8.494 1.488-0.420 1.00 0.00 ATOM 501 HD TRP 150-7.171 1.537 1.314 1.00 0.00 ATOM 502 3HE TRP 150-6. 993-2.315-2.046 1.00 0.00 ATOM 503 CZ3 TRP 150-8.545-1.469-3.236 1.00 0.00 ATOM 504 CZ2 TRP 150-9.511 0.622-2.526 1.00 0.00 ATOM 505 1HE TRP 150-9.006 2.317-0.304 1.00 0.00 ATOM 506 3HZ TRP 150-8.531-2.272-3.957 1.00 0.00 ATOM 507 CH2 TRP 150-9. 446-0.417-3.409 1.00 0.00 ATOM 508 2HZ TRP 150-10.217 1.428-2.675 1.00 0.00 ATOM 509 HH TRP 150-10.104-0.439-4.265 1.00 0.00 ATOM 510 C TRP 150-4. 744-3.102 0.920 1.00 0.00 ATOM 511 O TRP 150-3.712-3.247 0.284 1.00 0.00 ATOM 512 N HIS+ 151-4.898-3.527 2.168 1.00 0.00 ATOM 513 H HIS+ 151-5.761-3.395 2.616 1.00 0.00 ATOM 514 CA HIS+ 151-3.828-4.210 2.873 1.00 0.00 ATOM 515 HA HIS+ 151-2.976-3.550 2.915 1.00 0.00 ATOM 516 CB HIS+ 151-4.285-4.567 4.300 1.00 0.00 ATOM 517 1HB HIS+ 151-5.195-5.148 4.234 1.00 0.00 ATOM 518 2HB HIS+ 151-4.494-3.654 4.836 1.00 0.00 ATOM 519 QB HIS+ 151-4.845-4.401 4.535 1.00 0.00 ATOM 520 CG HIS+ 151-3.297-5.356 5.116 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.937-5.008 6.401 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.618-6.497 4.839 1.00 0.00 ATOM 523 1HD HIS+ 151-3.260-4.224 6.895 1.00 0.00 ATOM 524 CE1 HIS+ 151-2.083-5.898 6.873 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.874-6.812 5.947 1.00 0.00 ATOM 526 2HD HIS+ 151-2. 651-7.049 3.906 1.00 0.00 ATOM 527 1HE HIS+ 151-1.622-5.875 7.852 1.00 0.00 ATOM 528 2HE HIS+ 151-1.379-7.647 6.082 1.00 0.00 ATOM 529 C HIS+ 151-3.453-5.465 2.099 1.00 0.00 ATOM 530 O HIS+ 151-2.276-5.746 1.886 1.00 0.00 ATOM 531 N THR 152-4.469-6.206 1.675 1.00 0.00 ATOM 532 H THR 152-5.385-5.920 1.872 1.00 0.00 ATOM 533 CA THR 152-4.259-7.423 0.915 1.00 0.00 ATOM 534 HA THR 152-3.530-8.019 1.444 1.00 0.00 ATOM 535 CB THR 152-5.564-8.219 0.802 1.00 0.00 ATOM 536 HB THR 152-6.224-7.715 0.108 1.00 0.00 ATOM 537 QG2 THR 152-5.325-9.975 0.193 1.00 0. 00 ATOM 538 OG1 THR 152-6.210-8.295 2.063 1.00 0.00 ATOM 539 1HG THR 152-6.501-7.417 2.333 1.00 0.00 ATOM 540 CG2 THR 152-5.370-9.638 0.312 1.00 0.00

ATOM 541 1HG2 THR 152-6.331-10.122 0.224 1.00 0.00 ATOM 542 2HG2 THR 152-4.756-10.182 1.013 1.00 0.00 ATOM 543 3HG2 THR 152-4.886-9.623-0.656 1.00 0.00 ATOM 544 C THR 152-3.698-7.103-0.461 1.00 0.00 ATOM 545 O THR 152-2.666-7.647-0. 824 1.00 0.00 ATOM 546 N VAL 153-4.361-6.209-1.206 1.00 0.00 ATOM 547 H VAL 153-5.176-5.791-0. 844 1.00 0.00 ATOM 548 CA VAL 153-3.897-5.822-2.542 1.00 0.00 ATOM 549 HA VAL 153-3.955-6.694-3. 175 1.00 0.00 ATOM 550 CB VAL 153-4.778-4.711-3.159 1.00 0.00 ATOM 551 HB VAL 153-4. 645-3.809-2. 579 1.00 0.00 ATOM 552 QG1 VAL 153-4.264-4.355-4.933 1.00 0.00 ATOM 553 QG2 VAL 153-6.593-5.195-3.095 1.00 0.00 ATOM 554 CG1 VAL 153-4.362-4.422-4.593 1.00 0.00 ATOM 555 1HG1 VAL 153-3.292-4.277-4.637 1.00 0.00 ATOM 556 2HG1 VAL 153-4.862-3.531-4.941 1.00 0.00 ATOM 557 3HG1 VAL 153-4.637-5.258-5.221 1.00 0.00 ATOM 558 CG2 VAL 153-6.246-5.101-3.106 1.00 0.00 ATOM 559 1HG2 VAL 153-6.603-5.028-2.089 1.00 0.00 ATOM 560 2HG2 VAL 153-6.358-6.119-3.455 1.00 0.00 ATOM 561 3HG2 VAL 153-6.817-4.439-3.739 1.00 0.00 ATOM 562 QQG VAL 153-5.429-4.775-4.014 1.00 0.00 ATOM 563 C VAL 153-2.449-5.361-2.495 1.00 0.00 ATOM 564 O VAL 153-1.623-5.771-3.309 1.00 0.00 ATOM 565 N ALA 154-2.145-4.529-1.519 1.00 0.00 ATOM 566 H ALA 154-2.849-4.252-0.887 1.00 0.00 ATOM 567 CA ALA 154-0.795-4.033-1.338 1.00 0.00 ATOM 568 HA ALA 154-0.475-3.555-2.252 1.00 0.00 ATOM 569 QB ALA 154-0.776-2.767 0.044 1.00 0.00 ATOM 570 CB ALA 154-0.780-3.010-0.221 1.00 0.00 ATOM 571 1HB ALA 154-0.357-3.455 0.668 1.00 0.00 ATOM 572 2HB ALA 154-1.790-2.685-0.016 1.00 0.00 ATOM 573 3HB ALA 154-0.180-2.162-0.519 1.00 0.00 ATOM 574 C ALA 154 0.153-5.176-1.011 1.00 0.00 ATOM 575 O ALA 154 1.233-5.300-1.595 1.00 0.00 ATOM 576 N LYS+ 155-0.261-6.007-0.065 1.00 0.00 ATOM 577 H LYS+ 155-1.133-5.847 0.360 1.00 0.00 ATOM 578 CA LYS+ 155 0.536-7.142 0.364 1.00 0.00 ATOM 579 HA LYS+ 155 1.500-6.764 0.691 1.00 0.00 ATOM 580 CB LYS+ 155-0.141-7.861 1.536 1.00 0.00 ATOM 581 1HB LYS+ 155-1.084-8.264 1.196 1.00 0.00 ATOM 582 2HB LYS+ 155-0.331-7.142 2.320 1.00 0.00 ATOM 583 QB LYS+ 155-0.708-7.703 1.758 1.00 0.00 ATOM 584 CG LYS+ 155 0.682-9.000 2.124 1.00 0.00 ATOM 585 1HG LYS+ 155 1.278-8.615 2.940 1.00 0.00 ATOM 586 2HG LYS+ 155 1.333-9.395 1.357 1.00 0.00 ATOM 587 QG LYS+ 155 1.305-9. 005 2.148 1.00 0.00 ATOM 588 CD LYS+ 155-0.207-10.122 2.646 1.00 0.00 ATOM 589 1HD LYS+ 155-1.237-9.793 2.617 1.00 0.00 ATOM 590 2HD LYS+ 155 0.072-10.342 3.667 1.00 0.00 ATOM 591 QD LYS+ 155-0.583-10.067 3.142 1.00 0.00 ATOM 592 CE LYS+ 155-0.067-11.391 1.813 1.00 0.00 ATOM 593 1HE LYS+ 155-0.976-11.970 1.909 1.00 0.00 ATOM 594 2HE LYS+ 155 0.764-11.966 2.195 1.00 0.00 ATOM 595 QE LYS+ 155-0.106-11.968 2.052 1.00 0.00 ATOM 596 NZ LYS+ 155 0.170-11.095 0.372 1.00 0.00 ATOM 597 1HZ LYS+ 155 1.189-10.912 0.205 1.00 0.00 ATOM 598 2HZ LYS+ 155-0.374-10.255 0.082 1.00 0.00 ATOM 599 3HZ LYS+ 155-0.126-11. 901-0.215 1.00 0.00 ATOM 600 QZ LYS+ 155 0.229-11.022 0.024 1.00 0.00 ATOM 601 C LYS+ 155 0.770-8.116-0.777 1.00 0.00 ATOM 602 O LYS+ 155 1.905-8.504-1.008 1.00 0.00 ATOM 603 N GLU 156-0.288-8.524-1.481 1.00 0.00 ATOM 604 H GLU 156-1.190-8.187-1.251 1.00 0.00 ATOM 605 CA GLU 156-0.127-9.469-2.583 1.00 0.00 ATOM 606 HA GLU 156 0.364-10.340-2.175 1.00 0.00 ATOM 607 CB GLU 156-1.465-9.913-3.187 1.00 0.00 ATOM 608 1HB GLU 156-1.963-10.567-2.485 1.00 0.00 ATOM 609 2HB GLU 156-1.267-10.466-4. 092 1. 00 0.00 ATOM 610 QB GLU 156-1.615-10.516-3.289 1.00 0.00 ATOM 611 CG GLU 156-2.417-8.788-3.533 1.00 0.00 ATOM 612 1HG GLU 156-2.253-8.492-4.560 1.00 0.00

ATOM 613 2HG GLU 156-2.224-7.950-2.878 1.00 0.00 ATOM 614 QG GLU 156-2. 239-8.221-3.719 1.00 0.00 ATOM 615 CD GLU 156-3. 862-9.204-3.375 1.00 0.00 ATOM 616 OE1 GLU 156-4. 111-10.203-2.669 1.00 0.00 ATOM 617 OE2 GLU 156-4. 740-8.528-3.946 1.00 0.00 ATOM 618 C GLU 156 0.783-8.896-3.658 1.00 0.00 ATOM 619 O GLU 156 1.635-9.605-4.165 1.00 0.00 ATOM 620 N THR 157 0.627-7.612-3.976 1.00 0.00 ATOM 621 H THR 157-0.066-7.081-3.520 1.00 0.00 ATOM 622 CA THR 157 1.482-6.972-4.977 1.00 0.00 ATOM 623 HA THR 157 1.306-7.463-5.923 1.00 0.00 ATOM 624 CB THR 157 1.132-5.482-5.107 1.00 0.00 ATOM 625 HB THR 157 1.258-5.008-4.143 1.00 0.00 ATOM 626 QG2 THR 157 2.199-4.563-6.344 1.00 0.00 ATOM 627 OG1 THR 157-0.215-5.312-5.510 1.00 0. 00 ATOM 628 1HG THR 157-0.807-5.653-4.824 1.00 0.00 ATOM 629 CG2 THR 157 1.995-4.739-6.105 1.00 0.00 ATOM 630 1HG2 THR 157 1.376-4.368-6.909 1.00 0. 00 ATOM 631 2HG2 THR 157 2.739-5.411-6.507 1.00 0.00 ATOM 632 3HG2 THR 157 2.483-3.911-5.615 1.00 0.00 ATOM 633 C THR 157 2.960-7.145-4.601 1.00 0.00 ATOM 634 O THR 157 3.816-7.363-5.459 1.00 0.00 ATOM 635 N CYS 158 3.254-7.055-3.311 1.00 0.00 ATOM 636 H CYS 158 2.532-6.877-2.663 1.00 0.00 ATOM 637 CA CYS 158 4.622-7.214-2.834 1.00 0.00 ATOM 638 HA CYS 158 5.279-6.789-3.579 1.00 0.00 ATOM 639 CB CYS 158 4. 806-6.446-1.527 1.00 0.00 ATOM 640 1HB CYS 158 5.659-6.833-1.001 1.00 0.00 ATOM 641 2HB CYS 158 3.927-6.583-0.918 1.00 0.00 ATOM 642 QB CYS 158 4.793-6.708-0.960 1.00 0.00 ATOM 643 SG CYS 158 5.048-4.648-1.768 1.00 0.00 ATOM 644 C CYS 158 4.990-8.696-2.666 1.00 0.00 ATOM 645 O CYS 158 6.080-9.109-3.065 1.00 0.00 ATOM 646 N SER 159 4.087-9.486-2.075 1.00 0.00 ATOM 647 H SER 159 3.243-9.094-1.769 1.00 0.00 ATOM 648 CA SER 159 4.320-10.919-1.857 1.00 0.00 ATOM 649 HA SER 159 5.266-11.022-1.344 1.00 0.00 ATOM 650 CB SER 159 3.221-11.526-0.984 1.00 0.00 ATOM 651 1HB SER 159 3.515-12.524-0.688 1.00 0.00 ATOM 652 2HB SER 159 2.304-11.577-1.553 1.00 0.00 ATOM 653 QB SER 159 2.909-12.050-1.121 1.00 0.00 ATOM 654 OG SER 159 2.992-10.751 0.185 1.00 0.00 ATOM 655 HG SER 159 3.841-10.503 0.571 1.00 0.00 ATOM 656 C SER 159 4.395-11.703-3.170 1.00 0.00 ATOM 657 O SER 159 5.041-12.744-3.222 1.00 0.00 ATOM 658 N GLU 160 3.732-11.207-4.220 1.00 0.00 ATOM 659 H GLU 160 3.224-10.371-4.120 1.00 0.00 ATOM 660 CA GLU 160 3.745-11.878-5.520 1.00 0.00 ATOM 661 HA GLU 160 3.429-12.901-5.376 1.00 0. 00 ATOM 662 CB GLU 160 2.796-11.183-6.504 1.00 0.00 ATOM 663 1HB GLU 160 3.344-10.421-7.038 1.00 0.00 ATOM 664 2HB GLU 160 1.996-10.715-5.949 1.00 0.00 ATOM 665 QB GLU 160 2.670-10.568-6.494 1.00 0.00 ATOM 666 CG GLU 160 2.177-12.123-7.527 1.00 0.00 ATOM 667 1HG GLU 160 1.456-12.754-7.030 1.00 0.00 ATOM 668 2HG GLU 160 2.957-12.735-7.954 1.00 0.00 ATOM 669 QG GLU 160 2.206-12.744-7.492 1.00 0.00 ATOM 670 CD GLU 160 1.479-11.382-8.648 1.00 0.00 ATOM 671 OE1 GLU 160 0.461-11.897-9.153 1.00 0.00 ATOM 672 OE2 GLU 160 1.951-10.287-9.020 1.00 0.00 ATOM 673 C GLU 160 5.165-11.868-6.064 1.00 0.00 ATOM 674 O GLU 160 5.592-12.774-6.781 1.00 0.00 ATOM 675 N LYS+ 161 5.901-10.843-5.665 1.00 0.00 ATOM 676 H LYS+ 161 5.502-10.181-5.067 1.00 0.00 ATOM 677 CA LYS+ 161 7.286-10.697-6.041 1.00 0.00 ATOM 678 HA LYS+ 161 7.450-11.250-6.955 1. 00 0.00 ATOM 679 CB LYS+ 161 7.637-9.219-6.255 1. 00 0.00 ATOM 680 1HB LYS+ 161 7.988-8.808-5.320 1.00 0.00 ATOM 681 2HB LYS+ 161 6.744-8.692-6. 554 1. 00 0.00 ATOM 682 QB LYS+ 161 7.366-8.750-5.937 1. 00 0. 00 ATOM 683 CG LYS+ 161 8.711-8.991-7. 312 1. 00 0. 00 ATOM 684 1HG LYS+ 161 8.248-8.566-8. 192 1. 00 0. 00

ATOM 685 2HG LYS+ 161 9.158-9. 941-7.565 1.00 0.00 ATOM 686 QG LYS+ 161 8.703-9. 253-7.879 1.00 0.00 ATOM 687 CD LYS+ 161 9.799-8.047-6.820 1.00 0.00 ATOM 688 1HD LYS+ 161 9.840-8.090-5.742 1.00 0.00 ATOM 689 2HD LYS+ 161 9.556-7. 041-7.133 1.00 0.00 ATOM 690 QD LYS+ 161 9.698-7. 565-6.438 1.00 0.00 ATOM 691 CE LYS+ 161 11.163-8.424-7.387 1.00 0.00 ATOM 692 1HE LYS+ 161 11.611-7. 544-7.828 1.00 0.00 ATOM 693 2HE LYS+ 161 11.024-9. 176-8.152 1.00 0.00 ATOM 694 QE LYS+ 161 11.317-8. 360-7.990 1.00 0.00 ATOM 695 NZ LYS+ 161 12.080-8.964-6.342 1.00 0.00 ATOM 696 1HZ LYS+ 161 12.083-8. 346-5.507 1.00 0.00 ATOM 697 2HZ LYS+ 161 13.049-9. 029-6.713 1.00 0.00 ATOM 698 3HZ LYS+ 161 11.771-9. 926-6.048 1.00 0.00 ATOM 699 QZ LYS+ 161 12.301-9. lOO-6.090 1.00 0.00 ATOM 700 C LYS+ 161 8.137-11. 292-4.930 1.00 0.00 ATOM 701 O LYS+ 161 7.817-12. 344-4.388 1.00 0.00 ATOM 702 N SER 162 9.208-10. 617-4.578 1.00 0.00 ATOM 703 H SER 162 9.417-9.779-5.026 1.00 0.00 ATOM 704 CA SER 162 10.066-11.095-3.518 1.00 0.00 ATOM 705 HA SER 162 9.643-12. 017-3.148 1.00 0.00 ATOM 706 CB SER 162 11.472-11. 376-4.049 1.00 0.00 ATOM 707 1HB SER 162 11.811-12. 331-3.669 1.00 0.00 ATOM 708 2HB SER 162 12.143-10. 599-3.711 1.00 0.00 ATOM 709 QB SER 162 11.977-11.465-3.690 1.00 0.00 ATOM 710 OG SER 162 11.483-11. 415-5.473 1.00 0.00 ATOM 711 HG SER 162 11.289-12.317-5.764 1.00 0.00 ATOM 712 C SER 162 10.122-10.094-2.371 1.00 0.00 ATOM 713 O SER 162 11.203-9.693-1.956 1.00 0.00 ATOM 714 N THR 163 8.960-9.673-1.864 1.00 0.00 ATOM 715 H THR 163 8.113-10. 009-2.239 1.00 0.00 ATOM 716 CA THR 163 8.925-8. 724-0.753 1.00 0.00 ATOM 717 HA THR 163 9.829-8. 866-0.176 1.00 0.00 ATOM 718 CB THR 163 8.884-7.276-1.243 1.00 0.00 ATOM 719 HB THR 163 8.708-6.640-0.379 1.00 0.00 ATOM 720 QG2 THR 163 10.464-6. 694-2.064 1.00 0.00 ATOM 721 OG1 THR 163 7.832-7.085-2.172 1.00 0.00 ATOM 722 1HG THR 163 7.496-7.947-2.459 1.00 0.00 ATOM 723 CG2 THR 163 10.160-6.805-1.906 1.00 0.00 ATOM 724 1HG2 THR 163 10.849-7. 634-1.986 1.00 0.00 ATOM 725 2HG2 THR 163 10.607-6.022-1.312 1.00 0.00 ATOM 726 3HG2 THR 163 9.936-6. 427-2.892 1.00 0.00 ATOM 727 C THR 163 7.728-8.978 0.165 1.00 0.00 ATOM 728 O THR 163 6.722-9. 559-0.239 1.00 0.00 ATOM 729 N ASN 164 7.842-8. 515 1.400 1.00 0.00 ATOM 730 H ASN 164 8.672-8. 051 1.655 1.00 0.00 ATOM 731 CA ASN 164 6.774-8. 665 2.395 1.00 0.00 ATOM 732 HA ASN 164 5.923-9. 124 1.902 1.00 0.00 ATOM 733 CB ASN 164 7.238-9. 557 3.556 1.00 0.00 ATOM 734 1HB ASN 164 7.047-10. 589 3.305 1.00 0.00 ATOM 735 2HB ASN 164 6.682-9.299 4.446 1.00 0.00 ATOM 736 QB ASN 164 6.864-9. 944 3.875 1.00 0.00 ATOM 737 CG ASN 164 8.719-9. 402 3.856 1.00 0.00 ATOM 738 OD1 ASN 164 9.393-10. 361 4.206 1.00 0.00 ATOM 739 ND2 ASN 164 9.225-8.181 3.739 1.00 0.00 ATOM 740 1HD2 ASN 164 8.617-7.454 3.491 1.00 0.00 ATOM 741 2HD2 ASN 164 10.187-8.065 3.847 1.00 0.00 ATOM 742 QD2 ASN 164 9.402-7. 759 3.669 1.00 0.00 ATOM 743 C ASN 164 6.360-7.299 2.943 1.00 0.00 ATOM 744 O ASN 164 7.214-6. 468 3.242 1.00 0.00 ATOM 745 N LEU 165 5. 060-7. 067 3.071 1.00 0.00 ATOM 746 H LEU 165 4.424-7. 764 2.819 1.00 0.00 ATOM 747 CA LEU 165 4.557-5. 788 3.581 1.00 0.00 ATOM 748 HA LEU 165 5.077-4. 992 3.070 1.00 0.00 ATOM 749 CB LEU 165 3.056-5.649 3.317 1. 00 0. 00 ATOM 750 1HB LEU 165 2.559-5. 470 4.259 1.00 0.00 ATOM 751 2HB LEU 165 2.692-6.578 2.905 1.00 0.00 ATOM 752 QB LEU 165 2.625-6. 024 3.582 1.00 0.00 ATOM 753 CG LEU 165 2.672-4.523 2.375 1.00 0.00 ATOM 754 HG LEU 165 3.180-3. 618 2.674 1.00 0.00 ATOM 755 QD1 LEU 165 3.199-4. 937 0.628 1. 00 0.00 ATOM 756 QD2 LEU 165 0.821-4.212 2.457 1.00 0.00

ATOM 757 CD1 LEU 165 3.099-4.859 0.965 1.00 0. 00 ATOM 758 1HD1 LEU 165 3.921-4.220 0. 676 1.00 0.00 ATOM 759 2HD1 LEU 165 2.267-4.702 0.291 1.00 0.00 ATOM 760 3HD1 LEU 165 3.411-5.891 0.919 1.00 0.00 ATOM 761 CD2 LEU 165 1.177-4.272 2.442 1.00 0.00 ATOM 762 1HD2 LEU 165 0.938-3.374 1.891 1.00 0.00 ATOM 763 2HD2 LEU 165 0.876-4.153 3.473 1.00 0.00 ATOM 764 3HD2 LEU 165 0.650-5.110 2.008 1.00 0.00 ATOM 765 QQD LEU 165 2.010-4.575 1.543 1.00 0.00 ATOM 766 C LEU 165 4.806-5.641 5.070 1.00 0.00 ATOM 767 O LEU 165 4.425-6.499 5.862 1.00 0.00 ATOM 768 N HIS+ 166 5.435-4.538 5.435 1.00 0.00 ATOM 769 H HIS+ 166 5.706-3.891 4.747 1.00 0.00 ATOM 770 CA HIS+ 166 5.729-4.248 6.824 1.00 0.00 ATOM 771 HA HIS+ 166 5.391-5.084 7.418 1.00 0. 00 ATOM 772 CB HIS+ 166 7.242-4.076 7.012 1.00 0.00 ATOM 773 1HB HIS+ 166 7.581-3.266 6.380 1.00 0.00 ATOM 774 2HB HIS+ 166 7.740-4.986 6.719 1.00 0.00 ATOM 775 QB HIS+ 166 7.660-4.126 6.549 1.00 0.00 ATOM 776 CG HIS+ 166 7.653-3.761 8.417 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.568-4.662 9.456 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.149-2.624 8.947 1.00 0.00 ATOM 779 1HD HIS+ 166 7.237-5.583 9.392 1.00 0.00 ATOM 780 CE1 HIS+ 166 7.995-4.086 10.568 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.354-2.844 10.284 1.00 0. 00 ATOM 782 2HD HIS+ 166 8.331-1.696 8.413 1.00 0.00 ATOM 783 1HE HIS+ 166 8.042-4.550 11.542 1.00 0.00 ATOM 784 2HE HIS+ 166 8.501-2.138 10.948 1.00 0. 00 ATOM 785 C HIS+ 166 4.982-2.989 7. 272 1.00 0. 00 ATOM 786 O HIS+ 166 4.328-2.987 8.315 1.00 0.00 ATOM 787 N ASP 167 5.085-1.920 6.479 1.00 0.00 ATOM 788 H ASP 167 5.622-1.982 5.659 1.00 0.00 ATOM 789 CA ASP 167 4.423-0.654 6.813 1.00 0. 00 ATOM 790 HA ASP 167 3.912-0.795 7.754 1.00 0.00 ATOM 791 CB ASP 167 5.443 0.483 6.975 1.00 0.00 ATOM 792 1HB ASP 167 5.053 1.205 7.678 1.00 0.00 ATOM 793 2HB ASP 167 5.585 0.965 6.021 1.00 0.00 ATOM 794 QB ASP 167 5.319 1.085 6.849 1.00 0.00 ATOM 795 CG ASP 167 6.795 0.018 7.473 1.00 0.00 ATOM 796 OD1 ASP 167 7.071 0.180 8.679 1.00 0.00 ATOM 797 OD2 ASP 167 7.587-0.502 6.655 1.00 0.00 ATOM 798 C ASP 167 3.394-0.251 5.757 1.00 0.00 ATOM 799 O ASP 167 3.707 0.463 4.809 1.00 0.00 ATOM 800 N TYR 168 2.167-0.711 5.933 1.00 0.00 ATOM 801 H TYR 168 1.983-1.271 6.715 1.00 0.00 ATOM 802 CA TYR 168 1.070-0.397 5.015 1.00 0.00 ATOM 803 HA TYR 168 1.490-0.171 4.037 1.00 0.00 ATOM 804 CB TYR 168 0.134-1.602 4.900 1.00 0.00 ATOM 805 1HB TYR 168 0.463-2.230 4.087 1.00 0.00 ATOM 806 2HB TYR 168-0.868-1.253 4.701 1.00 0.00 ATOM 807 QB TYR 168-0.203-1.741 4.394 1.00 0.00 ATOM 808 QD TYR 168 0.093-2.537 6.306 1.00 0.00 ATOM 809 QE TYR 168 0.047-3.880 8.364 1.00 0. 00 ATOM 810 QR TYR 168 0.070-3.209 7.335 1.00 0. 00 ATOM 811 CG TYR 168 0.095-2.443 6.160 1.00 0.00 ATOM 812 CD1 TYR 168-0.750-2.110 7.211 1.00 0.00 ATOM 813 1HD TYR 168-1.391-1.247 7.116 1.00 0.00 ATOM 814 CE1 TYR 168-0.777-2.862 8.370 1. 00 0. 00 ATOM 815 1HE TYR 168-1.441-2.586 9.176 1.00 0.00 ATOM 816 CZ TYR 168 0.044-3.961 8.489 1.00 0.00 ATOM 817 CE2 TYR 168 0.891-4.313 7.459 1. 00 0. oo ATOM 818 2HE TYR 168 1.536-5.175 7.552 1.00 0.00 ATOM 819 CD2 TYR 168 0.914-3.556 6.304 1. 00 0. 00 ATOM 820 2HD TYR 168 1.577-3.828 5. 497 1. 00 0. 00 ATOM 821 OH TYR 168 0.017-4.712 9.639 1. 00 0. 00 ATOM 822 HH TYR 168 0.823-4.558 10.142 1.00 0.00 ATOM 823 C TYR 168 0.284 0. 817 5.505 1. 00 o. oo ATOM 824 O TYR 168 0.119 1.016 6.708 1. 00 0. 00 ATOM 825 N GLY 169-0.219 1.604 4.571 1.00 0.00 ATOM 826 H GLY 169-0.072 1.385 3.625 1.00 0.00 ATOM 827 CA GLY 169-1.000 2.773 4.915 1. oo 0. 00 ATOM 828 1HA GLY 169-0.355 3.641 4.923 1.00 0.00

ATOM 829 2HA GLY 169-1.427 2.638 5.898 1.00 0.00 ATOM 830 QA GLY 169-0.891 3.140 5.410 1.00 0.00 ATOM 831 C GLY 169-2.103 2.988 3.913 1.00 0.00 ATOM 832 O GLY 169-1.938 2.669 2.743 1.00 0.00 ATOM 833 N MET 170-3.229 3.510 4.353 1.00 0.00 ATOM 834 H MET 170-3.314 3.744 5.299 1.00 0.00 ATOM 835 CA MET 170-4.350 3.747 3.454 1.00 0.00 ATOM 836 HA MET 170-4.030 3.494 2.442 1.00 0.00 ATOM 837 CB MET 170-5.557 2.885 3.850 1.00 0.00 ATOM 838 1HB MET 170-6.458 3.435 3.617 1.00 0.00 ATOM 839 2HB MET 170-5.523 2.715 4.915 1.00 0.00 ATOM 840 QB MET 170-5.991 3.075 4.266 1.00 0.00 ATOM 841 CG MET 170-5.639 1.527 3.160 1.00 0.00 ATOM 842 1HG MET 170-6.058 1.673 2.173 1.00 0.00 ATOM 843 2HG MET 170-6.297 0.892 3.732 1.00 0.00 ATOM 844 QG MET 170-6.178 1.283 2.952 1.00 0.00 ATOM 845 SD MET 170-4. 050 0.693 2.989 1.00 0.00 ATOM 846 QE MET 170-4.214-0.844 4.477 1.00 0.00 ATOM 847 CE MET 170-4. 186-0.586 4.228 1.00 0.00 ATOM 848 1HE MET 170-3.221-0.750 4.684 1.00 0.00 ATOM 849 2HE MET 170-4.527-1.501 3.765 1.00 0.00 ATOM 850 3HE MET 170-4.894-0.281 4.984 1.00 0.00 ATOM 851 C MET 170-4.739 5.216 3.503 1.00 0.00 ATOM 852 O MET 170-5.090 5.738 4.561 1.00 0.00 ATOM 853 N LEU 171-4.670 5.879 2.364 1.00 0.00 ATOM 854 H LEU 171-4.379 5.409 1.553 1.00 0.00 ATOM 855 CA LEU 171-5.007 7.292 2.289 1.00 0.00 ATOM 856 HA LEU 171-5.131 7.652 3.299 1.00 0.00 ATOM 857 CB LEU 171-3.875 8.072 1.622 1.00 0.00 ATOM 858 1HB LEU 171-3.916 9.093 1.970 1.00 0.00 ATOM 859 2HB LEU 171-4.042 8.068 0.552 1.00 0.00 ATOM 860 QB LEU 171-3.979 8.581 1.261 1.00 0.00 ATOM 861 CG LEU 171-2.472 7.532 1.892 1.00 0.00 ATOM 862 HG LEU 171-2.529 6.751 2.637 1.00 0.00 ATOM 863 QD1 LEU 171-1.741 6.792 0.328 1.00 0.00 ATOM 864 QD2 LEU 171-1.364 8.894 2.559 1.00 0.00 ATOM 865 CD1 LEU 171-1.881 6.932 0.628 1.00 0.00 ATOM 866 1HD1 LEU 171-2.249 5.926 0.500 1.00 0.00 ATOM 867 2HD1 LEU 171-0.804 6.915 0.709 1.00 0.00 ATOM 868 3HD1 LEU 171-2.170 7.533-0.224 1.00 0.00 ATOM 869 CD2 LEU 171-1.576 8.634 2.432 1.00 0.00 ATOM 870 1HD2 LEU 171-0.568 8.257 2.537 1.00 0.00 ATOM 871 2HD2 LEU 171-1.942 8.956 3.395 1.00 0.00 ATOM 872 3HD2 LEU 171-1.580 9.468 1.746 1.00 0.00 ATOM 873 QQD LEU 171-1.553 7.843 1.444 1.00 0.00 ATOM 874 C LEU 171-6.307 7.510 1.529 1.00 0.00 ATOM 875 O LEU 171-7.044 6. 555 1.270 1.00 0.00 ATOM 876 N LEU 172-6.562 8.778 1.183 1.00 0.00 ATOM 877 H LEU 172-5.910 9.464 1.429 1.00 0.00 ATOM 878 CA LEU 172-7.762 9.199 0.449 1.00 0.00 ATOM 879 HA LEU 172-7.925 10.242 0.674 1.00 0.00 ATOM 880 CB LEU 172-7.551 9.061-1.061 1.00 0.00 ATOM 881 1HB LEU 172-8.437 8.612-1.484 1.00 0.00 ATOM 882 2HB LEU 172-6.715 8.397-1.232 1.00 0.00 ATOM 883 QB LEU 172-7.576 8.505-1.358 1.00 0.00 ATOM 884 CG LEU 172-7.285 10.377-1.796 1.00 0.00 ATOM 885 HG LEU 172-7.247 10.186-2.857 1.00 0. 00 ATOM 886 QD1 LEU 172-8.669 11. 609-1. 477 1.00 0.00 ATOM 887 QD2 LEU 172-5.633 11.109-1.279 1.00 0.00 ATOM 888 CD1 LEU 172-8.404 11.373-1.538 1.00 0.00 ATOM 889 1HD1 LEU 172-8.026 12.192-0.944 1.00 0.00 ATOM 890 2HD1 LEU 172-9.207 10.883-1.006 1.00 0.00 ATOM 891 3HD1 LEU 172-8.774 11.751-2.479 1.00 0.00 ATOM 892 CD2 LEU 172-5.950 10.969-1.378 1.00 0.00 ATOM 893 1HD2 LEU 172-5.636 11.702-2.106 1.00 0.00 ATOM 894 2HD2 LEU 172-5.210 10.182-1.319 1.00 0.00 ATOM 895 3HD2 LEU 172-6.051 11.441-0.412 1.00 0.00 ATOM 896 QQD LEU 172-7.151 11.359-1.378 1.00 0.00 ATOM 897 C LEU 172-9.004 8.422 0.875 1.00 0.00 ATOM 898 O LEU 172-9.488 7.563 0.139 1.00 0.00 ATOM 899 N PRO 173-9.543 8.711 2.071 1.00 0.00 ATOM 900 CD PRO 173-9.044 9.722 3.019 1.00 0.00

ATOM 901 CA PRO 173-10.734 8.027 2.575 1.00 0.00 ATOM 902 HA PRO 173-10. 546 6. 972 2.726 1.00 0.00 ATOM 903 CB PRO 173-11.011 8.706 3.921 1.00 0.00 ATOM 904 1HB PRO 173-11.317 7. 964 4.644 1.00 0.00 ATOM 905 2HB PRO 173-11.793 9.442 3.800 1.00 0.00 ATOM 906 QB PRO 173-11.555 8.703 4.222 1.00 0.00 ATOM 907 CG PRO 173-9.717 9.341 4.307 1.00 0.00 ATOM 908 1HG PRO 173-9.109 8.634 4.854 1.00 0.00 ATOM 909 2HG PRO 173-9.904 10.219 4.908 1.00 0. 00 ATOM 910 QG PRO 173-9.507 9.427 4.881 1.00 0. 00 ATOM 911 1HD PRO 173-7.970 9.659 3.119 1.00 0.00 ATOM 912 2HD PRO 173-9.341 10.716 2.716 1.00 0.00 ATOM 913 QD PRO 173-8.656 10.188 2.917 1.00 0.00 ATOM 914 C PRO 173-11.920 8.198 1.633 1.00 0.00 ATOM 915 O PRO 173-12.120 9.265 1.051 1.00 0.00 ATOM 916 N CYS 174-12. 693 7.140 1.475 1.00 0.00 ATOM 917 H CYS 174-12.478 6.314 1.960 1.00 0.00 ATOM 918 CA CYS 174-13. 847 7.167 0.593 1.00 0.00 ATOM 919 HA CYS 174-13.905 8.156 0. 162 1.00 0.00 ATOM 920 CB CYS 174-13.660 6. 146-0.531 1.00 0.00 ATOM 921 1HB CYS 174-13.106 5.302-0.146 1.00 0.00 ATOM 922 2HB CYS 174-13.093 6.604-1.326 1.00 0.00 ATOM 923 QB CYS 174-13. 100 5.953-0.736 1.00 0.00 ATOM 924 SG CYS 174-15.203 5.509-1.257 1.00 0.00 ATOM 925 C CYS 174-15.129 6.900 1.375 1.00 0.00 ATOM 926 O CYS 174-16.204 7.368 1.007 1.00 0.00 ATOM 927 N GLY 175-15.003 6.164 2.469 1.00 0.00 ATOM 928 H GLY 175-14.116 5.831 2.727 1.00 0.00 ATOM 929 CA GLY 175-16.151 5.865 3.300 1.00 0.00 ATOM 930 1HA GLY 175-16.558 4.909 3.010 1.00 0.00 ATOM 931 2HA GLY 175-16. 901 6.630 3.151 1.00 0.00 ATOM 932 QA GLY 175-16.730 5.770 3.080 1.00 0.00 ATOM 933 C GLY 175-15.770 5.820 4.761 1.00 0.00 ATOM 934 O GLY 175-14.728 6.349 5.138 1.00 0.00 ATOM 935 N ILE 176-16.597 5.177 5.581 1.00 0.00 ATOM 936 H ILE 176-17.408 4.766 5.221 1.00 0.00 ATOM 937 CA ILE 176-16.310 5.061 7.008 1.00 0.00 ATOM 938 HA ILE 176-16.149 6.058 7.394 1.00 0.00 ATOM 939 CB ILE 176-17.498 4.423 7.779 1.00 0.00 ATOM 940 HB ILE 176-18.245 5.189 7.926 1.00 0.00 ATOM 941 QG2 ILE 176-18.288 3.035 6.781 1.00 0. 00 ATOM 942 CG2 ILE 176-18.137 3.300 6.970 1.00 0.00 ATOM 943 1HG2 ILE 176-17.363 2.680 6.543 1.00 0.00 ATOM 944 2HG2 ILE 176-18.741 3.722 6.181 1.00 0.00 ATOM 945 3HG2 ILE 176-18.759 2.701 7.620 1.00 0.00 ATOM 946 CG1 ILE 176-17.050 3.903 9.149 1.00 0. 00 ATOM 947 1HG1 ILE 176-16.569 4.705 9.692 1.00 0.00 ATOM 948 2HG1 ILE 176-16.344 3.097 9.009 1.00 0. 00 ATOM 949 QG1 ILE 176-16.457 3.901 9.350 1.00 0.00 ATOM 950 QD1 ILE 176-18.457 3.255 10.202 1.00 0.00 ATOM 951 CD1 ILE 176-18.187 3.380 10.000 1.00 0.00 ATOM 952 1HD1 ILE 176-17.790 2.964 10.914 1.00 0. 00 ATOM 953 2HD1 ILE 176-18.718 2.613 9.456 1.00 0.00 ATOM 954 3HD1 ILE 176-18.863 4.188 10.236 1.00 0.00 ATOM 955 C ILE 176-15.029 4.244 7.214 1.00 0.00 ATOM 956 O ILE 176-14.140 4.643 7.964 1.00 0.00 ATOM 957 N ASP 177-14. 938 3.117 6.509 1.00 0.00 ATOM 958 H ASP 177-15.671 2.874 5.913 1.00 0.00 ATOM 959 CA ASP 177-13.763 2.253 6.572 1.00 0.00 ATOM 960 HA ASP 177-12.979 2.795 7.084 1.00 0.00 ATOM 961 CB ASP 177-14. 061 0.961 7.342 1.00 0.00 ATOM 962 1HB ASP 177-14.620 0.291 6.708 1.00 0.00 ATOM 963 2HB ASP 177-14.647 1.197 8.217 1. 00 0.00 ATOM 964 QB ASP 177-14.634 0. 744 7.462 1. 00 0.00 ATOM 965 CG ASP 177-12.795 0.252 7.792 1. 00 0.00 ATOM 966 OD1 ASP 177-11.714 0.880 7.761 1. 00 0.00 ATOM 967 OD2 ASP 177-12.882-0.935 8.164 1.00 0. 00 ATOM 968 C ASP 177-13.290 1.923 5.158 1. 00 0. 00 ATOM 969 O ASP 177-12.630 0.912 4.911 1.00 0.00 ATOM 970 N LYS+ 178-13.629 2.794 4.220 1.00 0. 00 ATOM 971 H LYS+ 178-14. 146 3.587 4.470 1. 00 0.00 ATOM 972 CA LYS+ 178-13.231 2.607 2.833 1. 00 0.00

ATOM 973 HA LYS+ 178-12.724 1.656 2.760 1.00 0.00 ATOM 974 CB LYS+ 178-14.440 2.612 1.894 1.00 0.00 ATOM 975 1HB LYS+ 178-14.104 2.341 0.902 1.00 0.00 ATOM 976 2HB LYS+ 178-14.848 3.611 1.862 1.00 0.00 ATOM 977 QB LYS+ 178-14.476 2.976 1.382 1.00 0.00 ATOM 978 CG LYS+ 178-15.557 1.653 2.300 1.00 0.00 ATOM 979 1HG LYS+ 178-16.375 1.755 1.602 1.00 0.00 ATOM 980 2HG LYS+ 178-15.894 1.911 3.292 1.00 0.00 ATOM 981 QG LYS+ 178-16.135 1.833 2.447 1.00 0.00 ATOM 982 CD LYS+ 178-15.087 0.204 2.303 1.00 0.00 ATOM 983 1HD LYS+ 178-15.405-0.263 3.225 1.00 0.00 ATOM 984 2HD LYS+ 178-14.008 0. 187 2.244 1.00 0.00 ATOM 985 QD LYS+ 178-14.707-0.038 2.734 1.00 0.00 ATOM 986 CE LYS+ 178-15.657-0.584 1.127 1.00 0.00 ATOM 987 1HE LYS+ 178-15.175-0.248 0.218 1.00 0.00 ATOM 988 2HE LYS+ 178-16.718-0.393 1.061 1.00 0.00 ATOM 989 QE LYS+ 178-15.947-0.320 0.639 1.00 0.00 ATOM 990 NZ LYS+ 178-15.437-2.050 1.277 1.00 0.00 ATOM 991 1HZ LYS+ 178-16. 344-2.543 1.376 1.00 0.00 ATOM 992 2HZ LYS+ 178-14.851-2.249 2.118 1.00 0.00 ATOM 993 3HZ LYS+ 178-14.940-2.432 0.429 1.00 0.00 ATOM 994 QZ LYS+ 178-15.379-2.408 1.307 1.00 0.00 ATOM 995 C LYS+ 178-12.253 3.691 2.440 1.00 0.00 ATOM 996 O LYS+ 178-12.380 4.835 2.871 1.00 0.00 ATOM 997 N PHE 179-11.266 3.329 1.639 1.00 0.00 ATOM 998 H PHE 179-11.210 2.399 1.329 1.00 0.00 ATOM 999 CA PHE 179-10.252 4.276 1.223 1.00 0.00 ATOM 1000 HA PHE 179-10.599 5.268 1.465 1.00 0.00 ATOM 1001 CB PHE 179-8.942 4.011 1.965 1.00 0.00 ATOM 1002 1HB PHE 179-8.216 4.720 1.628 1.00 0.00 ATOM 1003 2HB PHE 179-8.590 3.023 1.725 1.00 0.00 ATOM 1004 QB PHE 179-8.403 3.872 1.676 1.00 0.00 ATOM 1005 QD PHE 179-9.061 4.140 3.629 1.00 0.00 ATOM 1006 QE PHE 179-9.251 4.340 6.073 1.00 0.00 ATOM 1007 QR PHE 179-9.194 4.281 5.340 1.00 0.00 ATOM 1008 CG PHE 179-9.048 4.127 3.462 1.00 0.00 ATOM 1009 CD1 PHE 179-8.642 5.282 4.109 1.00 0.00 ATOM 1010 1HD PHE 179-8.241 6.100 3.529 1.00 0.00 ATOM 1011 CE1 PHE 179-8.747 5.397 5.482 1.00 0.00 ATOM 1012 1HE PHE 179-8.426 6.304 5.974 1.00 0.00 ATOM 1013 CZ PHE 179-9.261 4.353 6.225 1.00 0.00 ATOM 1014 HZ PHE 179-9.346 4.442 7.299 1.00 0.00 ATOM 1015 CE2 PHE 179-9.668 3.195 5.593 1.00 0.00 ATOM 1016 2HE PHE 179-10.075 2.376 6.172 1.00 0.00 ATOM 1017 CD2 PHE 179-9.561 3.086 4.221 1.00 0.00 ATOM 1018 2HD PHE 179-9.881 2.179 3.729 1.00 0.00 ATOM 1019 C PHE 179-9.998 4.187-0.264 1.00 0.00 ATOM 1020 O PHE 179-10.675 3.448-0.981 1.00 0.00 ATOM 1021 N ARG+ 180-9.006 4.938-0.712 1.00 0. 00 ATOM 1022 H ARG+ 180-8.511 5.498-0.072 1.00 0.00 ATOM 1023 CA ARG+ 180-8. 621 4.962-2.113 1.00 0.00 ATOM 1024 HA ARG+ 180-9.010 4.072-2.585 1.00 0.00 ATOM 1025 CB ARG+ 180-9.215 6.195-2.806 1.00 0.00 ATOM 1026 1HB ARG+ 180-9.041 6.112-3.868 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.710 7.076-2.439 1.00 0.00 ATOM 1028 QB ARG+ 180-8.876 6.594-3.154 1.00 0.00 ATOM 1029 CG ARG+ 180-10.709 6.366-2.574 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.860 6.789-1.590 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.182 5.397-2.626 1.00 0.00 ATOM 1032 QG ARG+ 180-11.021 6.093-2.108 1.00 0.00 ATOM 1033 CD ARG+ 180-11.341 7.281-3.606 1.00 0.00 ATOM 1034 1HD ARG+ 180-10.577 7.936-4.003 1.00 0.00 ATOM 1035 2HD ARG+ 180-12.103 7.874-3.122 1.00 0.00 ATOM 1036 QD ARG+ 180-11.340 7.905-3.563 1.00 0.00 ATOM 1037 NE ARG+ 180-11.947 6.535-4.709 1.00 0.00 ATOM 1038 HE ARG+ 180-11.654 5.601-4.841 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.851 7.056-5.540 1.00 0. 00 ATOM 1040 NH1 ARG+ 180-13.245 8.315-5.380 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.862 8.869-4.639 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.918 8.715-6.002 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13. 390 8. 792-5. 321 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.351 6.328-6.532 1.00 0.00

ATOM 1045 1HH2 ARG+ 180-13.051 5.378-6.666 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-14.019 6.726-7.162 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13.535 6.052-6.914 1.00 0.00 ATOM 1048 C ARG+ 180-7.099 4.972-2.252 1.00 0.00 ATOM 1049 O ARG+ 180-6. 566 4.681-3.314 1.00 0.00 ATOM 1050 N GLY 181-6.400 5.312-1.179 1.00 0.00 ATOM 1051 H GLY 181-6.865 5.534-0.344 1.00 0.00 ATOM 1052 CA GLY 181-4.950 5.360-1.235 1.00 0.00 ATOM 1053 1HA GLY 181-4.615 6.296-0.809 1.00 0.00 ATOM 1054 2HA GLY 181-4.644 5.324-2.270 1.00 0.00 ATOM 1055 QA GLY 181-4.630 5.810-1.540 1.00 0.00 ATOM 1056 C GLY 181-4.288 4.219-0.494 1.00 0.00 ATOM 1057 O GLY 181-4.862 3.660 0.440 1.00 0.00 ATOM 1058 N VAL 182-3.073 3.878-0.916 1.00 0.00 ATOM 1059 H VAL 182-2.680 4.372-1.658 1.00 0.00 ATOM 1060 CA VAL 182-2.301 2.799-0.305 1.00 0.00 ATOM 1061 HA VAL 182-2.632 2.685 0.721 1.00 0.00 ATOM 1062 CB VAL 182-2.490 1.446-1.040 1.00 0.00 ATOM 1063 HB VAL 182-1.697 1.352-1.770 1.00 0.00 ATOM 1064 QG1 VAL 182-2.334 0. 015 0.165 1.00 0.00 ATOM 1065 QG2 VAL 182-4.136 1.356-1.951 1.00 0.00 ATOM 1066 CG1 VAL 182-2. 363 0.289-0.066 1.00 0.00 ATOM 1067 1HG1 VAL 182-1.357-0.102-0.099 1.00 0.00 ATOM 1068 2HG1 VAL 182-3. 061-0.489-0.339 1.00 0.00 ATOM 1069 3HG1 VAL 182-2.583 0.635 0.934 1.00 0.00 ATOM 1070 CG2 VAL 182-3.821 1.373-1.777 1.00 0.00 ATOM 1071 1HG2 VAL 182-4.591 1.835-1.177 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.077 0.339-1.956 1.00 0.00 ATOM 1073 3HG2 VAL 182-3.739 1.892-2.720 1.00 0.00 ATOM 1074 QQG VAL 182-3.235 0.685-0.893 1.00 0.00 ATOM 1075 C VAL 182-0.805 3.132-0.311 1.00 0.00 ATOM 1076 O VAL 182-0.223 3.383-1.366 1.00 0.00 ATOM 1077 N GLU 183-0.193 3.117 0.866 1.00 0.00 ATOM 1078 H GLU 183-0.720 2.899 1.671 1.00 0.00 ATOM 1079 CA GLU 183 1.234 3.398 1.015 1.00 0.00 ATOM 1080 HA GLU 183 1.676 3.428 0.029 1.00 0.00 ATOM 1081 CB GLU 183 1.446 4.745 1.711 1.00 0.00 ATOM 1082 1HB GLU 183 1.589 5.508 0.960 1.00 0.00 ATOM 1083 2HB GLU 183 2.335 4. 684 2.322 1.00 0.00 ATOM 1084 QB GLU 183 1.962 5.096 1.641 1.00 0.00 ATOM 1085 CG GLU 183 0.291 5.166 2.602 1.00 0.00 ATOM 1086 1HG GLU 183-0.122 4.287 3.073 1.00 0.00 ATOM 1087 2HG GLU 183-0.465 5.639 1.993 1.00 0.00 ATOM 1088 QG GLU 183-0.294 4.963 2.533 1.00 0.00 ATOM 1089 CD GLU 183 0.715 6.136 3.680 1.00 0.00 ATOM 1090 OE1 GLU 183 0.276 5.964 4.834 1.00 0.00 ATOM 1091 OE2 GLU 183 1.482 7.070 3.365 1.00 0.00 ATOM 1092 C GLU 183 1.891 2.286 1.826 1.00 0.00 ATOM 1093 O GLU 183 1.884 2.311 3.050 1.00 0.00 ATOM 1094 N PHE 184 2.420 1.287 1.147 1.00 0.00 ATOM 1095 H PHE 184 2.373 1.294 0.174 1.00 0.00 ATOM 1096 CA PHE 184 3.023 0.148 1.827 1.00 0.00 ATOM 1097 HA PHE 184 2.871 0.289 2.885 1.00 0.00 ATOM 1098 CB PHE 184 2.335-1.154 1.405 1.00 0.00 ATOM 1099 1HB PHE 184 1.413-1.265 1.958 1.00 0.00 ATOM 1100 2HB PHE 184 2.985-1. 981 1.651 1.00 0.00 ATOM 1101 QB PHE 184 2.199-1.623 1.804 1.00 0.00 ATOM 1102 QD PHE 184 1.975-1.265-0.241 1.00 0.00 ATOM 1103 QE PHE 184 1.429-1.494-2.626 1.00 0.00 ATOM 1104 QR PHE 184 1.591-1.428-1.910 1.00 0.00 ATOM 1105 CG PHE 184 2.015-1.255-0.071 1.00 0.00 ATOM 1106 CD1 PHE 184 2.629-2.217-0.853 1.00 0.00 ATOM 1107 1HD PHE 184 3.357-2.875-0.405 1.00 0.00 ATOM 1108 CE1 PHE 184 2.321-2.349-2.193 1.00 0.00 ATOM 1109 1HE PHE 184 2.810-3.107-2.786 1.00 0.00 ATOM 1110 CZ PHE 184 1.395-1.512-2.773 1.00 0.00 ATOM 1111 HZ PHE 184 1.146-1.623-3.817 1.00 0.00 ATOM 1112 CE2 PHE 184 0.775-0.541-2.013 1.00 0.00 ATOM 1113 2HE PHE 184 0.049 0.119-2.466 1.00 0.00 ATOM 1114 CD2 PHE 184 1.080-0.418-0.670 1.00 0.00 ATOM 1115 2HD PHE 184 0.594 0.345-0.077 1.00 0. 00 ATOM 1116 C PHE 184 4.513 0.012 1.567 1.00 0.00

ATOM 1117 O PHE 184 4.993 0.271 0.469 1.00 0.00 ATOM 1118 N VAL 185 5.232-0.434 2.586 1.00 0.00 ATOM 1119 H VAL 185 4.780-0.642 3.431 1.00 0.00 ATOM 1120 CA VAL 185 6.664-0.652 2.487 1.00 0.00 ATOM 1121 HA VAL 185 6.989-0.338 1.504 1.00 0.00 ATOM 1122 CB VAL 185 7.440 0. 160 3.552 1.00 0.00 ATOM 1123 HB VAL 185 7.583-0.467 4.425 1.00 0.00 ATOM 1124 QG1 VAL 185 9.125 0.666 2.909 1.00 0.00 ATOM 1125 QG2 VAL 185 6.477 1.686 4.083 1.00 0.00 ATOM 1126 CG1 VAL 185 8.803 0.567 3.031 1.00 0.00 ATOM 1127 lHGl VAL 185 8.801 1.625 2.813 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.026 0.014 2.132 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.550 0.357 3.782 1.00 0.00 ATOM 1130 CG2 VAL 185 6.662 1.393 3.980 1.00 0.00 ATOM 1131 1HG2 VAL 185 6.897 2.216 3.321 1.00 0.00 ATOM 1132 2HG2 VAL 185 6.933 1.654 4.993 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.603 1.186 3.935 1.00 0.00 ATOM 1134 QQG VAL 185 7.801 1.176 3.496 1.00 0.00 ATOM 1135 C VAL 185 6.957-2.142 2.654 1.00 0.00 ATOM 1136 O VAL 185 6.697-2.721 3.706 1.00 0.00 ATOM 1137 N CYS 186 7.469-2.770 1.604 1.00 0.00 ATOM 1138 H CYS 186 7.636-2.266 0.776 1.00 0.00 ATOM 1139 CA CYS 186 7.765-4.197 1.646 1.00 0.00 ATOM 1140 HA CYS 186 7.511-4.555 2.635 1.00 0.00 ATOM 1141 CB CYS 186 6.908-4.952 0.620 1.00 0.00 ATOM 1142 1HB CYS 186 5.884-4.966 0.966 1.00 0.00 ATOM 1143 2HB CYS 186 7.267-5.966 0.545 1.00 0.00 ATOM 1144 QB CYS 186 6.575-5.466 0.755 1.00 0.00 ATOM 1145 SG CYS 186 6.913-4.248-1.060 1.00 0.00 ATOM 1146 C CYS 186 9.247-4.459 1.400 1.00 0.00 ATOM 1147 O CYS 186 9.811-3.981 0.425 1.00 0.00 ATOM 1148 N CYS 187 9.879-5.222 2.284 1.00 0.00 ATOM 1149 H CYS 187 9.381-5.586 3.049 1.00 0.00 ATOM 1150 CA CYS 187 11.305-5.524 2.139 1.00 0.00 ATOM 1151 HA CYS 187 11.751-4.720 1.575 1.00 0.00 ATOM 1152 CB CYS 187 11.995-5.608 3.505 1.00 0.00 ATOM 1153 1HB CYS 187 12.788-6.341 3.452 1.00 0.00 ATOM 1154 2HB CYS 187 11.275-5.919 4.246 1. 00 0.00 ATOM 1155 QB CYS 187 12.031-6.130 3.849 1.00 0.00 ATOM 1156 SG CYS 187 12.726-4.039 4.069 1.00 0.00 ATOM 1157 C CYS 187 11.529-6.822 1.386 1.00 0.00 ATOM 1158 O CYS 187 10. 709-7. 731 1.456 1.00 0.00 ATOM 1159 N PRO 188 12.645-6.907 0.639 1.00 0.00 ATOM 1160 CD PRO 188 13.650-5.836 0. 489 1.00 0.00 ATOM 1161 CA PRO 188 12.990-8.096-0.150 1.00 0.00 ATOM 1162 HA PRO 188 12.262-8.279-0.925 1.00 0.00 ATOM 1163 CB PRO 188 14.337-7.737-0.787 1.00 0.00 ATOM 1164 1HB PRO 188 14.363-8.100-1.804 1.00 0.00 ATOM 1165 2HB PRO 188 15.135-8.193-0.218 1.00 0.00 ATOM 1166 QB PRO 188 14.749-8.146-1.011 1.00 0.00 ATOM 1167 CG PRO 188 14.414-6.249-0.737 1.00 0.00 ATOM 1168 1HG PRO 188 13.960-5.827-1.621 1.00 0.00 ATOM 1169 2HG PRO 188 15.445-5.938-0.659 1.00 0.00 ATOM 1170 QG PRO 188 14.702-5.882-1.140 1.00 0.00 ATOM 1171 1HD PRO 188 13.174-4.880 0.329 1.00 0.00 ATOM 1172 2HD PRO 188 14.305-5.792 1.348 1.00 0.00 ATOM 1173 QD PRO 188 13.739-5.336 0.838 1.00 0.00 ATOM 1174 C PRO 188 13.140-9.353 0. 704 1.00 0.00 ATOM 1175 O PRO 188 13.892-9.366 1.682 1.00 0.00 ATOM 1176 N LEU 189 12.429-10.399 0.308 1.00 0.00 ATOM 1177 H LEU 189 11.863-10.311-0.488 1.00 0.00 ATOM 1178 CA LEU 189 12.468-11.680 0.990 1.00 0.00 ATOM 1179 HA LEU 189 13.331-11.688 1.639 1.00 0.00 ATOM 1180 CB LEU 189 11.204-11.889 1.825 1.00 0.00 ATOM 1181 1HB LEU 189 10.394-12.131 1.155 1.00 0.00 ATOM 1182 2HB LEU 189 10.971-10.961 2.327 1.00 0.00 ATOM 1183 QB LEU 189 10.682-11.546 1.741 1.00 0.00 ATOM 1184 CG LEU 189 11.301-12.996 2.876 1.00 0.00 ATOM 1185 HG LEU 189 11.897-13.806 2.477 1.00 0.00 ATOM 1186 QD1 LEU 189 12.147-12.362 4.428 1.00 0.00 ATOM 1187 QD2 LEU 189 9.595-13.669 3.283 1.00 0.00 ATOM 1188 CD1 LEU 189 11.986-12.484 4.132 1.00 0.00

ATOM 1189 1HD1 LEU 189 12.905-11.986 3.862 1.00 0. 00 ATOM 1190 2HD1 LEU 189 12.205-13.314 4.786 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.333-11.788 4.638 1.00 0.00 ATOM 1192 CD2 LEU 189 9.922-13.541 3.205 1.00 0.00 ATOM 1193 1HD2 LEU 189 9.439-13.870 2.297 1.00 0.00 ATOM 1194 2HD2 LEU 189 9.330-12.765 3.667 1.00 0.00 ATOM 1195 3HD2 LEU 189 10.017-14.374 3.885 1.00 0.00 ATOM 1196 QQD LEU 189 10.871-13.016 3.856 1.00 0.00 ATOM 1197 C LEU 189 12.603-12.802-0.034 1.00 0.00 ATOM 1198 OT1 LEU 189 13.067-13.898 0.339 1.00 0.00 ATOM 1199 OT2 LEU 189 12.244-12.569-1.210 1.00 0.00 TER ENDMDL MODEL 17 ATOM 1 N SER 124 7.485 14.146 3.608 1.00 0.00 ATOM 2 CA SER 124 7.748 14.982 2.411 1.00 0. 00 ATOM 3 HA SER 124 6.826 15.116 1.865 1.00 0.00 ATOM 4 CB SER 124 8.259 16.336 2.897 1.00 0.00 ATOM 5 1HB SER 124 7.708 17.127 2.409 1.00 0.00 ATOM 6 2HB SER 124 9.311 16.430 2.661 1.00 0.00 ATOM 7 QB SER 124 8.509 16.778 2.535 1.00 0.00 ATOM 8 OG SER 124 8.089 16.455 4.304 1.00 0.00 ATOM 9 HG SER 124 8.852 16.911 4.684 1.00 0.00 ATOM 10 C SER 124 8.775 14.315 1.513 1.00 0.00 ATOM 11 O SER 124 8.501 14.007 0.356 1.00 0.00 ATOM 12 1HT SER 124 7.537 14.736 4.465 1.00 0.00 ATOM 13 2HT SER 124 8.197 13.390 3.678 1.00 0.00 ATOM 14 3HT SER 124 6.542 13.717 3.547 1.00 0.00 ATOM 15 N ASP 125 9.948 14.087 2.079 1.00 0.00 ATOM 16 H ASP 125 10.081 14.353 3.015 1.00 0.00 ATOM 17 CA ASP 125 11.054 13.440 1.387 1.00 0.00 ATOM 18 HA ASP 125 11.241 13.966 0.464 1.00 0.00 ATOM 19 CB ASP 125 12.296 13.502 2.276 1.00 0.00 ATOM 20 1HB ASP 125 12.940 14.299 1.937 1.00 0.00 ATOM 21 2HB ASP 125 12.825 12.562 2.215 1.00 0.00 ATOM 22 QB ASP 125 12.882 13.430 2.076 1.00 0.00 ATOM 23 CG ASP 125 11.933 13.757 3.727 1.00 0.00 ATOM 24 OD1 ASP 125 11.159 12.954 4.296 1.00 0.00 ATOM 25 OD2 ASP 125 12.379 14.778 4.278 1.00 0.00 ATOM 26 C ASP 125 10.711 11.988 1.088 1.00 0.00 ATOM 27 O ASP 125 10.749 11.547-0.060 1.00 0.00 ATOM 28 N ALA 126 10.378 11.254 2.142 1.00 0.00 ATOM 29 H ALA 126 10.377 11.675 3.031 1.00 0.00 ATOM 30 CA ALA 126 10.025 9.849 2.022 1.00 0.00 ATOM 31 HA ALA 126 10.774 9.371 1.407 1.00 0.00 ATOM 32 QB ALA 126 10.047 9.026 3.713 1.00 0.00 ATOM 33 CB ALA 126 10.043 9.183 3.390 1.00 0.00 ATOM 34 1HB ALA 126 10. 563 8.239 3.324 1.00 0.00 ATOM 35 2HB ALA 126 9.029 9.014 3.720 1.00 0.00 ATOM 36 3HB ALA 126 10.550 9.825 4.096 1.00 0.00 ATOM 37 C ALA 126 8.662 9.672 1.367 1.00 0.00 ATOM 38 O ALA 126 7.627 9.706 2.035 1.00 0.00 ATOM 39 N LEU 127 8.674 9.479 0.058 1.00 0.00 ATOM 40 H LEU 127 9.531 9.463-0.409 1.00 0.00 ATOM 41 CA LEU 127 7.453 9.282-0.706 1.00 0.00 ATOM 42 HA LEU 127 6.638 9.170-0.010 1.00 0.00 ATOM 43 CB LEU 127 7.193 10.495-1.611 1.00 0.00 ATOM 44 1HB LEU 127 7.666 10.310-2.564 1.00 0.00 ATOM 45 2HB LEU 127 7.662 11.358-1.161 1. 00 0.00 ATOM 46 QB LEU 127 7.664 10.834-1.863 1.00 0.00 ATOM 47 CG LEU 127 5.718 10.833-1.870 1.00 0.00 ATOM 48 HG LEU 127 5.635 11.888-2.091 1.00 0.00 ATOM 49 QD1 LEU 127 5.061 9.886-3.354 1. 00 0. 00 ATOM 50 QD2 LEU 127 4.671 10.477-0.347 1.00 0.00 ATOM 51 CD1 LEU 127 5.187 10.067-3.070 1.00 0.00 ATOM 52 1HD1 LEU 127 4.121 10.216-3.148 1.00 0.00 ATOM 53 2HD1 LEU 127 5.396 9.014-2.946 1.00 0.00 ATOM 54 3HD1 LEU 127 5. 667 10.427-3.968 1.00 0.00 ATOM 55 CD2 LEU 127 4.872 10.546-0.638 1.00 0.00 ATOM 56 1HD2 LEU 127 5.484 10.627 0.247 1.00 0.00 ATOM 57 2HD2 LEU 127 4.466 9.546-0.705 1.00 0. 00 ATOM 58 3HD2 LEU 127 4.062 11.259-0. 583 1. 00 0. 00

ATOM 59 QQD LEU 127 4.866 10.181-1.851 1.00 0.00 ATOM 60 C LEU 127 7.584 8.010-1.537 1.00 0.00 ATOM 61 O LEU 127 6.596 7.432-1.989 1.00 0.00 ATOM 62 N LEU 128 8.825 7.576-1.720 1.00 0.00 ATOM 63 H LEU 128 9.564 8.075-1.324 1.00 0.00 ATOM 64 CA LEU 128 9.120 6.376-2.479 1.00 0.00 ATOM 65 HA LEU 128 8.192 5.862-2.670 1.00 0.00 ATOM 66 CB LEU 128 9.781 6.760-3.815 1.00 0.00 ATOM 67 1HB LEU 128 10.852 6.760-3.667 1.00 0.00 ATOM 68 2HB LEU 128 9.475 7.767-4.058 1.00 0.00 ATOM 69 QB LEU 128 10.163 7.263-3.863 1.00 0. 00 ATOM 70 CG LEU 128 9.468 5.865-5.029 1.00 0.00 ATOM 71 HG LEU 128 8.986 6.468-5.788 1.00 0.00 ATOM 72 QD1 LEU 128 11.053 5.177-5.772 1.00 0.00 ATOM 73 QD2 LEU 128 8.291 4.467-4.583 1.00 0.00 ATOM 74 CD1 LEU 128 10.749 5.309-5.629 1.00 0.00 ATOM 75 1HD1 LEU 128 10.772 4.237-5.499 1.00 0.00 ATOM 76 2HD1 LEU 128 11.601 5.750-5.133 1.00 0.00 ATOM 77 3HD1 LEU 128 10.785 5.543-6.682 1.00 0.00 ATOM 78 CD2 LEU 128 8.517 4.734-4.668 1.00 0.00 ATOM 79 1HD2 LEU 128 8.750 4.367-3.680 1.00 0.00 ATOM 80 2HD2 LEU 128 8.623 3.933-5.384 1.00 0.00 ATOM 81 3HD2 LEU 128 7.501 5.100-4.685 1.00 0.00 ATOM 82 QQD LEU 128 9. 672 4.822-5.178 1.00 0.00 ATOM 83 C LEU 128 10.034 5.473-1.647 1.00 0.00 ATOM 84 O LEU 128 10.022 5.548-0.420 1.00 0.00 ATOM 85 N VAL 129 10.814 4.632-2.317 1.00 0.00 ATOM 86 H VAL 129 10.769 4.630-3.295 1.00 0.00 ATOM 87 CA VAL 129 11.735 3.710-1.648 1.00 0.00 ATOM 88 HA VAL 129 11.149 3.007-1.078 1.00 0.00 ATOM 89 CB VAL 129 12.564 2.921-2.689 1.00 0.00 ATOM 90 HB VAL 129 13.194 3.621-3.219 1.00 0.00 ATOM 91 QG1 VAL 129 13.680 1.654-1.857 1.00 0.00 ATOM 92 QG2 VAL 129 11.436 2.085-3.940 1.00 0.00 ATOM 93 CG1 VAL 129 13.465 1.896-2.016 1.00 0.00 ATOM 94 1HG1 VAL 129 12.910 1.370-1.254 1.00 0.00 ATOM 95 2HG1 VAL 129 14.307 2.400-1.564 1.00 0.00 ATOM 96 3HG1 VAL 129 13.822 1.192-2.753 1.00 0.00 ATOM 97 CG2 VAL 129 11.651 2.245-3.700 1.00 0.00 ATOM 98 1HG2 VAL 129 11.894 2.594-4.693 1.00 0.00 ATOM 99 2HG2 VAL 129 10.623 2.485-3.475 1.00 0.00 ATOM 100 3HG2 VAL 129 11.791 1.175-3.651 1.00 0.00 ATOM 101 QQG VAL 129 12.558 1.869-2.899 1.00 0.00 ATOM 102 C VAL 129 12.691 4.442-0.699 1.00 0.00 ATOM 103 O VAL 129 13.487 5.274-1.131 1.00 0.00 ATOM 104 N PRO 130 12.614 4.137 0.613 1.00 0.00 ATOM 105 CD PRO 130 11.681 3.165 1.206 1.00 0. 00 ATOM 106 CA PRO 130 13.469 4.755 1.622 1.00 0.00 ATOM 107 HA PRO 130 13.602 5.803 1.432 1.00 0.00 ATOM 108 CB PRO 130 12.673 4.569 2.916 1.00 0.00 ATOM 109 1HB PRO 130 12.067 5.446 3.094 1.00 0.00 ATOM 110 2HB PRO 130 13.357 4.429 3.740 1.00 0.00 ATOM 111 QB PRO 130 12.712 4.937 3.417 1.00 0.00 ATOM 112 CG PRO 130 11.824 3.357 2.698 1.00 0.00 ATOM 113 1HG PRO 130 10.852 3.510 3.147 1.00 0.00 ATOM 114 2HG PRO 130 12.303 2.495 3.136 1.00 0.00 ATOM 115 QG PRO 130 11.577 3.002 3.141 1.00 0.00 ATOM 116 1HD PRO 130 10.666 3.374 0.899 1.00 0.00 ATOM 117 2HD PRO 130 11.955 2.157 0.929 1.00 0.00 ATOM 118 QD PRO 130 11.310 2.765 0.914 1.00 0.00 ATOM 119 C PRO 130 14.845 4.093 1.713 1.00 0.00 ATOM 120 O PRO 130 15.739 4.388 0.925 1.00 0.00 ATOM 121 N ASP 131 15.000 3.209 2.688 1.00 0.00 ATOM 122 H ASP 131 14.248 3.035 3.280 1.00 0.00 ATOM 123 CA ASP 131 16.263 2.504 2.905 1.00 0.00 ATOM 124 HA ASP 131 17.065 3.175 2.637 1. 00 0. 00 ATOM 125 CB ASP 131 16.401 2.130 4.389 1.00 0.00 ATOM 126 1HB ASP 131 15.606 1.454 4.660 1. 00 0.00 ATOM 127 2HB ASP 131 16.325 3.026 4.986 1.00 0.00 ATOM 128 QB ASP 131 15.965 2.240 4.823 1.00 0.00 ATOM 129 CG ASP 131 17.725 1.464 4.706 1. oo 0. 00 ATOM 130 OD1 ASP 131 17.715 0.253 5.013 1. 00 0. 00

ATOM 131 OD2 ASP 131 18.763 2.148 4.646 1.00 0.00 ATOM 132 C ASP 131 16.360 1.250 2.025 1.00 0.00 ATOM 133 0 ASP 131 16.666 1.332 0.837 1.00 0.00 ATOM 134 N LYS+ 132 16.112 0.088 2.620 1.00 0.00 ATOM 135 H LYS+ 132 15.891 0.082 3.575 1.00 0.00 ATOM 136 CA LYS+ 132 16.193-1.177 1.897 1.00 0.00 ATOM 137 HA LYS+ 132 16.746-1.001 0.987 1.00 0.00 ATOM 138 CB LYS+ 132 16.941-2.210 2.744 1.00 0.00 ATOM 139 1HB LYS+ 132 16.219-2.854 3.224 1.00 0.00 ATOM 140 2HB LYS+ 132 17.505-1.689 3.506 1.00 0.00 ATOM 141 QB LYS+ 132 16.862-2.272 3.365 1.00 0.00 ATOM 142 CG LYS+ 132 17.903-3.077 1.949 1.00 0.00 ATOM 143 1HG LYS+ 132 18.838-3. 140 2.486 1. 00 0.00 ATOM 144 2HG LYS+ 132 18.068-2.620 0.984 1.00 0.00 ATOM 145 QG LYS+ 132 18.453-2.880 1.735 1.00 0.00 ATOM 146 CD LYS+ 132 17.349-4.481 1.745 1.00 0.00 ATOM 147 1HD LYS+ 132 16.447-4.416 1.150 1.00 0.00 ATOM 148 2HD LYS+ 132 17.114-4.908 2.709 1.00 0.00 ATOM 149 QD LYS+ 132 16. 780-4.662 1.929 1.00 0.00 ATOM 150 CE LYS+ 132 18.347-5.384 1.035 1.00 0.00 ATOM 151 1HE LYS+ 132 18.108-5.403-0.020 1.00 0.00 ATOM 152 2HE LYS+ 132 18.259-6.383 1.439 1.00 0.00 ATOM 153 QE LYS+ 132 18.183-5.893 0.709 1.00 0.00 ATOM 154 NZ LYS+ 132 19.750-4.910 1.209 1.00 0.00 ATOM 155 1HZ LYS+ 132 20.372-5.367 0.511 1.00 0.00 ATOM 156 2HZ LYS+ 132 20.091-5.141 2.164 1.00 0.00 ATOM 157 3HZ LYS+ 132 19.798-3.878 1.077 1.00 0.00 ATOM 158 QZ LYS+ 132 20.087-4.795 1.250 1.00 0.00 ATOM 159 C LYS+ 132 14.809-1.708 1.540 1.00 0.00 ATOM 160 O LYS+ 132 14.679-2.679 0.794 1.00 0.00 ATOM 161 N CYS 133 13.778-1.078 2.073 1.00 0.00 ATOM 162 H CYS 133 13.939-0.314 2.660 1.00 0.00 ATOM 163 CA CYS 133 12.411-1.499 1.802 1.00 0.00 ATOM 164 HA CYS 133 12.433-2.544 1.532 1.00 0.00 ATOM 165 CB CYS 133 11.532-1.319 3.043 1.00 0.00 ATOM 166 1HB CYS 133 10.528-1.077 2.725 1.00 0.00 ATOM 167 2HB CYS 133 11.918-0.499 3.627 1.00 0.00 ATOM 168 QB CYS 133 11.223-0.788 3.176 1.00 0.00 ATOM 169 SG CYS 133 11.429-2.772 4.138 1.00 0.00 ATOM 170 C CYS 133 11.828-0.700 0.647 1.00 0.00 ATOM 171 O CYS 133 12.249 0.418 0.386 1.00 0.00 ATOM 172 N LYS+ 134 10.851-1.274-0.033 1.00 0.00 ATOM 173 H LYS+ 134 10.545-2.169 0.231 1.00 0.00 ATOM 174 CA LYS+ 134 10.201-0.611-1.152 1.00 0.00 ATOM 175 HA LYS+ 134 10.874 0.141-1.537 1.00 0.00 ATOM 176 CB LYS+ 134 9.884-1.624-2.255 1.00 0.00 ATOM 177 1HB LYS+ 134 8.903-2.040-2.070 1.00 0.00 ATOM 178 2HB LYS+ 134 10.614-2.420-2.215 1.00 0.00 ATOM 179 QB LYS+ 134 9.758-2.230-2.143 1.00 0.00 ATOM 180 CG LYS+ 134 9.896-1.036-3.657 1.00 0.00 ATOM 181 1HG LYS+ 134 10.712-0.331-3.733 1.00 0.00 ATOM 182 2HG LYS+ 134 8.960-0.528-3.833 1.00 0.00 ATOM 183 QG LYS+ 134 9.836-0.430-3.783 1.00 0.00 ATOM 184 CD LYS+ 134 10.079-2.118-4.712 1.00 0.00 ATOM 185 1HD LYS+ 134 10.695-2.906-4.301 1.00 0.00 ATOM 186 2HD LYS+ 134 10.570-1.690-5.574 1.00 0.00 ATOM 187 QD LYS+ 134 10. 632-2. 298-4.938 1.00 0.00 ATOM 188 CE LYS+ 134 8.744-2.710-5.145 1.00 0.00 ATOM 189 1HE LYS+ 134 8.322-3.259-4.314 1.00 0.00 ATOM 190 2HE LYS+ 134 8.916-3.385-5.971 1.00 0.00 ATOM 191 QE LYS+ 134 8.619-3.322-5.143 1.00 0.00 ATOM 192 NZ LYS+ 134 7.780-1. 656-5.572 1.00 0.00 ATOM 193 1HZ LYS+ 134 7.047-1.522-4.841 1.00 0.00 ATOM 194 2HZ LYS+ 134 7.317-1.932-6.461 1.00 0.00 ATOM 195 3HZ LYS+ 134 8.275-0.754-5.718 1. 00 0.00 ATOM 196 QZ LYS+ 134 7.546-1.403-5.674 1.00 0.00 ATOM 197 C LYS+ 134 8.922 0.056-0.678 1.00 0.00 ATOM 198 O LYS+ 134 7.956-0.623-0.348 1.00 0.00 ATOM 199 N PHE 135 8.919 1.378-0.639 1.00 0.00 ATOM 200 H PHE 135 9.721 1.868-0.913 1.00 0.00 ATOM 201 CA PHE 135 7.749 2.121-0.192 1.00 0.00 ATOM 202 HA PHE 135 7.180 1.483 0.469 1.00 0.00

ATOM 203 CB PHE 135 8.182 3.377 0.569 1.00 0.00 ATOM 204 1HB PHE 135 8.711 4.032-0.111 1.00 0.00 ATOM 205 2HB PHE 135 8.847 3.090 1.368 1.00 0.00 ATOM 206 QB PHE 135 8.779 3.561 0.628 1.00 0.00 ATOM 207 QD PHE 135 6.932 4.253 1.248 1.00 0.00 ATOM 208 QE PHE 135 5.106 5.554 2.260 1.00 0.00 ATOM 209 QR PHE 135 5.653 5.164 1.956 1.00 0.00 ATOM 210 CG PHE 135 7.055 4.164 1.179 1.00 0.00 ATOM 211 CD1 PHE 135 7.111 5.548 1.218 1.00 0.00 ATOM 212 1HD PHE 135 7.968 6.056 0.798 1.00 0.00 ATOM 213 CE1 PHE 135 6.088 6.281 1.786 1.00 0.00 ATOM 214 1HE PHE 135 6.144 7.360 1.811 1.00 0.00 ATOM 215 CZ PHE 135 4.993 5.635 2.322 1.00 0.00 ATOM 216 HZ PHE 135 4.190 6.206 2.768 1. 00 0.00 ATOM 217 CE2 PHE 135 4.925 4.256 2.289 1.00 0.00 ATOM 218 2HE PHE 135 4.069 3.748 2.709 1.00 0.00 ATOM 219 CD2 PHE 135 5.951 3.529 1.721 1.00 0.00 ATOM 220 2HD PHE 135 5.896 2.450 1.698 1. 00 0.00 ATOM 221 C PHE 135 6.881 2.496-1.380 1.00 0.00 ATOM 222 O PHE 135 7.280 3.293-2.227 1.00 0.00 ATOM 223 N LEU 136 5.700 1.903-1.443 1.00 0.00 ATOM 224 H LEU 136 5.445 1.267-0.737 1.00 0.00 ATOM 225 CA LEU 136 4.774 2.160-2.528 1.00 0.00 ATOM 226 HA LEU 136 5.306 2.692-3.302 1.00 0.00 ATOM 227 CB LEU 136 4.235 0.845-3.102 1.00 0.00 ATOM 228 1HB LEU 136 3.439 1.083-3.793 1.00 0.00 ATOM 229 2HB LEU 136 3.817 0.268-2.289 1.00 0.00 ATOM 230 QB LEU 136 3.628 0.675-3.041 1.00 0.00 ATOM 231 CG LEU 136 5.259-0.023-3.834 1.00 0.00 ATOM 232 HG LEU 136 6.055 0.604-4.203 1.00 0.00 ATOM 233 QD1 LEU 136 6.003-1.291-2.662 1.00 0.00 ATOM 234 QD2 LEU 136 4.454-0.881-5.300 1.00 0.00 ATOM 235 CD1 LEU 136 5.861-1.049-2.888 1.00 0.00 ATOM 236 1HD1 LEU 136 5.619-2.044-3.232 1.00 0.00 ATOM 237 2HD1 LEU 136 5.456-0.903-1.896 1.00 0.00 ATOM 238 3HD1 LEU 136 6.933-0.927-2.857 1.00 0.00 ATOM 239 CD2 LEU 136 4.610-0.716-5.020 1.00 0.00 ATOM 240 1HD2 LEU 136 4.809-1.777-4.971 1.00 0.00 ATOM 241 2HD2 LEU 136 5.012-0.315-5.938 1.00 0.00 ATOM 242 3HD2 LEU 136 3.542-0.550-4.991 1.00 0.00 ATOM 243 QQD LEU 136 5.228-1.086-3.981 1.00 0.00 ATOM 244 C LEU 136 3.615 3.015-2.047 1.00 0.00 ATOM 245 O LEU 136 2.539 2.502-1.750 1.00 0.00 ATOM 246 N HIS+ 137 3.833 4.317-1.984 1.00 0.00 ATOM 247 H HIS+ 137 4.710 4.671-2.242 1.00 0.00 ATOM 248 CA HIS+ 137 2.791 5.235-1.558 1. 00 0.00 ATOM 249 HA HIS+ 137 2.085 4.680-0.949 1.00 0.00 ATOM 250 CB HIS+ 137 3.387 6.391-0.735 1. 00 0.00 ATOM 251 1HB HIS+ 137 4.185 6.850-1.302 1.00 0.00 ATOM 252 2HB HIS+ 137 3.790 5.996 0.185 1.00 0.00 ATOM 253 QB HIS+ 137 3.987 6.423-0.559 1.00 0.00 ATOM 254 CG HIS+ 137 2.397 7.466-0.378 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.946 8.404-1.282 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.761 7.736 0.785 1.00 0.00 ATOM 257 1HD HIS+ 137 2.220 8.470-2.223 1.00 0.00 ATOM 258 CE1 HIS+ 137 1.075 9.201-0.690 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.942 8.817 0.567 1.00 0.00 ATOM 260 2HD HIS+ 137 1.874 7.196 1.720 1.00 0.00 ATOM 261 1HE HIS+ 137 0.549 10.022-1.157 1.00 0.00 ATOM 262 2HE HIS+ 137 0.201 9.083 1.155 1.00 0.00 ATOM 263 C HIS+ 137 2.081 5.777-2.792 1.00 0.00 ATOM 264 0 HIS+ 137 2.604 6.658-3.481 1.00 0.00 ATOM 265 N GLN 138 0.906 5.247-3.088 1.00 0.00 ATOM 266 H GLN 138 0.535 4.537-2.513 1.00 0.00 ATOM 267 CA GLN 138 0.160 5.690-4.256 1.00 0.00 ATOM 268 HA GLN 138 0.522 6.672-4.521 1.00 0.00 ATOM 269 CB GLN 138 0. 400 4. 740-5.434 1.00 0.00 ATOM 270 1HB GLN 138-0.443 4.798-6.106 1.00 0.00 ATOM 271 2HB GLN 138 0.478 3.732-5.057 1.00 0.00 ATOM 272 QB GLN 138 0.017 4.265-5.582 1. 00 0.00 ATOM 273 CG GLN 138 1.664 5.053-6.224 1.00 0.00 ATOM 274 1HG GLN 138 2.005 6.043-5.954 1.00 0.00

ATOM 275 2HG GLN 138 1.430 5.030-7.278 1.00 0.00 ATOM 276 QG GLN 138 1.717 5.536-6.616 1.00 0.00 ATOM 277 CD GLN 138 2.783 4.064-5.956 1.00 0.00 ATOM 278 OE1 GLN 138 2.603 2.855-6.095 1.00 0.00 ATOM 279 NE2 GLN 138 3.949 4.569-5.569 1.00 0.00 ATOM 280 1HE2 GLN 138 4.028 5.542-5.477 1.00 0.00 ATOM 281 2HE2 GLN 138 4.682 3.947-5.389 1.00 0.00 ATOM 282 QE2 GLN 138 4.355 4.744-5.433 1.00 0.00 ATOM 283 C GLN 138-1.328 5.784-3.953 1.00 0.00 ATOM 284 O GLN 138-1.891 4.929-3.268 1.00 0.00 ATOM 285 N GLU 139-1.954 6.829-4.471 1.00 0.00 ATOM 286 H GLU 139-1.448 7.470-5.008 1.00 0.00 ATOM 287 CA GLU 139-3.376 7.049-4.265 1.00 0.00 ATOM 288 HA GLU 139-3.682 6.460-3.413 1.00 0.00 ATOM 289 CB GLU 139-3.643 8.526-3.970 1.00 0.00 ATOM 290 1HB GLU 139-4.618 8.618-3.512 1.00 0.00 ATOM 291 2HB GLU 139-3.640 9.075-4.900 1.00 0.00 ATOM 292 QB GLU 139-4.129 8.846-4.206 1.00 0.00 ATOM 293 CG GLU 139-2.621 9.158-3.036 1.00 0.00 ATOM 294 1HG GLU 139-2.431 10.170-3.362 1.00 0.00 ATOM 295 2HG GLU 139-1.706 8.587-3.084 1.00 0.00 ATOM 296 QG GLU 139-2.069 9.378-3.223 1.00 0.00 ATOM 297 CD GLU 139-3.093 9.192-1.599 1.00 0.00 ATOM 298 OE1 GLU 139-2.521 9.965-0.805 1.00 0.00 ATOM 299 OE2 GLU 139-4.035 8.442-1.266 1.00 0.00 ATOM 300 C GLU 139-4.175 6.605-5.486 1.00 0.00 ATOM 301 O GLU 139-4.055 7.187-6.565 1.00 0.00 ATOM 302 N ARG+ 140-4.993 5.579-5.307 1.00 0.00 ATOM 303 H ARG+ 140-5.052 5.162-4.420 1.00 0.00 ATOM 304 CA ARG+ 140-5.823 5. 061-6. 385 1.00 0.00 ATOM 305 HA ARG+ 140-5.404 5.397-7.322 1.00 0.00 ATOM 306 CB ARG+ 140-5.844 3.524-6.358 1.00 0.00 ATOM 307 1HB ARG+ 140-6.381 3.201-5.475 1.00 0.00 ATOM 308 2HB ARG+ 140-4.829 3.162-6.303 1.00 0.00 ATOM 309 QB ARG+ 140-5.605 3.181-5.889 1.00 0.00 ATOM 310 CG ARG+ 140-6.512 2.893-7.571 1.00 0.00 ATOM 311 1HG ARG+ 140-7.440 3.413-7.768 1.00 0.00 ATOM 312 2HG ARG+ 140-6.719 1.856-7.356 1.00 0.00 ATOM 313 QG ARG+ 140-7.080 2.634-7.562 1.00 0.00 ATOM 314 CD ARG+ 140-5.631 2.974-8.808 1.00 0. 00 ATOM 315 1HD ARG+ 140-4.609 3.136-8.498 1.00 0.00 ATOM 316 2HD ARG+ 140-5.960 3.811-9.410 1.00 0.00 ATOM 317 QD ARG+ 140-5.285 3.473-8.954 1.00 0.00 ATOM 318 NE ARG+ 140-5.700 1.754-9.612 1.00 0.00 ATOM 319 HE ARG+ 140-5.361 0.927-9.206 1.00 0.00 ATOM 320 CZ ARG+ 140-6.175 1.716-10.859 1.00 0.00 ATOM 321 NH1 ARG+ 140-6.697 2.807-11.405 1.00 0.00 ATOM 322 1HH1 ARG+ 140-6.741 3.667-10.877 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.062 2.784-12.335 1.00 0.00 ATOM 324 QH1 ARG+ 140-6.902 3.225-11.606 1.00 0.00 ATOM 325 NH2 ARG+ 140-6.156 0.579-11.546 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.785-0.253-11.132 1.00 0.00 ATOM 327 2HH2 ARG+ 140-6.515 0.550-12.480 1.00 0.00 ATOM 328 QH2 ARG+ 140-6.150 0.148-11.806 1.00 0.00 ATOM 329 C ARG+ 140-7.239 5.604-6.249 1.00 0.00 ATOM 330 O ARG+ 140-8.086 4.989-5.603 1.00 0.00 ATOM 331 N MET 141-7. 497 6.756-6.861 1.00 0.00 ATOM 332 H MET 141-6.781 7.198-7.364 1.00 0.00 ATOM 333 CA MET 141-8.819 7.382-6.803 1.00 0.00 ATOM 334 HA MET 141-9.157 7.338-5.780 1.00 0.00 ATOM 335 CB MET 141-8.728 8.851-7.235 1.00 0.00 ATOM 336 1HB MET 141-8.745 8.895-8.315 1.00 0.00 ATOM 337 2HB MET 141-7.793 9.261-6.882 1.00 0. 00 ATOM 338 QB MET 141-8.269 9.078-7.599 1. 00 o. oo ATOM 339 CG MET 141-9.859 9.720-6.706 1.00 0.00 ATOM 340 1HG MET 141-10.478 9.121-6.054 1.00 0.00 ATOM 341 2HG MET 141-10.449 10.064-7.542 1.00 0.00 ATOM 342 QG MET 141-10.464 9.592-6.798 1. 00 0. 00 ATOM 343 SD MET 141-9. 271 11.155-5.787 1.00 0.00 ATOM 344 QE MET 141-8.054 12.126-7.273 1. 00 0.00 ATOM 345 CE MET 141-8.258 11.963-7.024 1.00 0.00 ATOM 346 1HE MET 141-8.241 11.365-7.923 1.00 0.00

ATOM 347 2HE MET 141-7.252 12.076-6.648 1.00 0.00 ATOM 348 3HE MET 141-8.670 12.937-7.247 1.00 0.00 ATOM 349 C MET 141-9. 828 6.639-7.686 1.00 0.00 ATOM 350 O MET 141-10.711 7.248-8.292 1.00 0.00 ATOM 351 N ASP 142-9.695 5.324-7.741 1.00 0.00 ATOM 352 H ASP 142-8.978 4.898-7.229 1.00 0.00 ATOM 353 CA ASP 142-10.572 4.490-8.530 1.00 0.00 ATOM 354 HA ASP 142-11.249 5.127-9.079 1.00 0.00 ATOM 355 CB ASP 142-9.752 3.659-9.512 1.00 0.00 ATOM 356 1HB ASP 142-10.423 3.088-10.124 1.00 0.00 ATOM 357 2HB ASP 142-9.118 2.984-8.959 1.00 0.00 ATOM 358 QB ASP 142-9.771 3.036-9.542 1.00 0.00 ATOM 359 CG ASP 142-8.877 4.500-10.414 1.00 0.00 ATOM 360 OD1 ASP 142-9.272 4.737-11.569 1.00 0.00 ATOM 361 OD2 ASP 142-7.772 4.890-9.977 1.00 0.00 ATOM 362 C ASP 142-11.364 3.555-7.635 1.00 0.00 ATOM 363 0 ASP 142-12.596 3.567-7.627 1.00 0.00 ATOM 364 N VAL 143-10.643 2.738-6.883 1.00 0.00 ATOM 365 H VAL 143-9.666 2.777-6.939 1.00 0.00 ATOM 366 CA VAL 143-11.264 1.773-5.992 1.00 0.00 ATOM 367 HA VAL 143-12.245 1.543-6.383 1.00 0.00 ATOM 368 CB VAL 143-10.442 0.465-5.941 1.00 0.00 ATOM 369 HB VAL 143-9.764 0.523-5.099 1.00 0.00 ATOM 370 QG1 VAL 143-11.560-1.021-5.687 1.00 0.00 ATOM 371 QG2 VAL 143-9.416 0.250-7.505 1.00 0.00 ATOM 372 CG1 VAL 143-11.347-0.736-5.735 1.00 0.00 ATOM 373 1HG1 VAL 143-11.676-0.767-4.707 1.00 0.00 ATOM 374 2HG1 VAL 143-10.800-1.638-5.965 1.00 0.00 ATOM 375 3HG1 VAL 143-12.203-0.658-6.387 1.00 0.00 ATOM 376 CG2 VAL 143-9.612 0.291-7.206 1.00 0.00 ATOM 377 1HG2 VAL 143-9.756-0.706-7.596 1.00 0.00 ATOM 378 2HG2 VAL 143-8.568 0.440-6.974 1.00 0.00 ATOM 379 3HG2 VAL 143-9.925 1.015-7.944 1.00 0.00 ATOM 380 QQG VAL 143-10.488-0.386-6.596 1.00 0.00 ATOM 381 C VAL 143-11.411 2.347-4.583 1.00 0.00 ATOM 382 O VAL 143-10.698 3.271-4.203 1.00 0.00 ATOM 383 N CYS 144-12.349 1.801-3.819 1.00 0.00 ATOM 384 H CYS 144-12.891 1.068-4.182 1.00 0.00 ATOM 385 CA CYS 144-12.599 2.254-2.453 1.00 0.00 ATOM 386 HA CYS 144-11.680 2.672-2.059 1.00 0.00 ATOM 387 CB CYS 144-13.688 3.325-2.431 1.00 0.00 ATOM 388 1HB CYS 144-14.631 2.861-2.179 1.00 0.00 ATOM 389 2HB CYS 144-13.764 3.773-3.410 1.00 0.00 ATOM 390 QB CYS 144-14.198 3.317-2.795 1.00 0.00 ATOM 391 SG CYS 144-13.387 4.663-1.229 1.00 0.00 ATOM 392 C CYS 144-13.012 1.084-1.585 1.00 0.00 ATOM 393 O CYS 144-14.152 0.631-1.658 1.00 0.00 ATOM 394 N GLU 145-12.084 0.587-0.778 1.00 0. 00 ATOM 395 H GLU 145-11. 187 0. 981-0. 772 1.00 0. 00 ATOM 396 CA GLU 145-12.360-0.547 0.081 1.00 0.00 ATOM 397 HA GLU 145-13.425-0.704 0.088 1.00 0.00 ATOM 398 CB GLU 145-11.693-1.785-0.489 1.00 0.00 ATOM 399 1HB GLU 145-11.428-2.446 0.320 1.00 0.00 ATOM 400 2HB GLU 145-10.790-1.488-1.008 1.00 0.00 ATOM 401 QB GLU 145-11.109-1.967-0.344 1.00 0.00 ATOM 402 CG GLU 145-12.593-2.543-1.451 1.00 0.00 ATOM 403 1HG GLU 145-12.160-3.513-1.645 1.00 0.00 ATOM 404 2HG GLU 145-12.665-1.988-2.375 1.00 0.00 ATOM 405 QG GLU 145-12.413-2.751-2.010 1.00 0.00 ATOM 406 CD GLU 145-13.986-2.735-0.890 1.00 0.00 ATOM 407 OE1 GLU 145-14.962-2.548-1.636 1.00 0.00 ATOM 408 OE2 GLU 145-14.103-3.047 0.315 1.00 0.00 ATOM 409 C GLU 145-11.890-0.306 1.506 1.00 0.00 ATOM 410 O GLU 145-11.358 0.757 1.827 1.00 0.00 ATOM 411 N THR 146-12.105-1.299 2.355 1.00 0.00 ATOM 412 H THR 146-12.542-2.116 2.031 1.00 0.00 ATOM 413 CA THR 146-11.724-1.211 3.755 1.00 0.00 ATOM 414 HA THR 146-11.969-0.216 4.098 1.00 0.00 ATOM 415 CB THR 146-12.529-2.227 4.570 1.00 0.00 ATOM 416 HB THR 146-11.984-3.159 4.605 1.00 0.00 ATOM 417 QG2 THR 146-12.859-1.684 6.337 1.00 0.00 ATOM 418 OG1 THR 146-13.786-2.467 3.959 1.00 0.00

ATOM 419 1HG THR 146-14.490-2.248 4.580 1.00 0.00 ATOM 420 CG2 THR 146-12.794-1.789 5.996 1.00 0.00 ATOM 421 1HG2 THR 146-13. 445-2.504 6.479 1.00 0.00 ATOM 422 2HG2 THR 146-13.269-0.816 5.995 1.00 0.00 ATOM 423 3HG2 THR 146-11.862-1.731 6.537 1.00 0.00 ATOM 424 C THR 146-10.220-1.434 3.935 1.00 0.00 ATOM 425 O THR 146-9.523-1.840 3.003 1.00 0.00 ATOM 426 N HIS+ 147-9.737-1.155 5.145 1.00 0.00 ATOM 427 H HIS+ 147-10.358-0.830 5.831 1.00 0.00 ATOM 428 CA HIS+ 147-8.321-1. 300 5.492 1.00 0.00 ATOM 429 HA HIS+ 147-7.762-0.574 4.921 1.00 0.00 ATOM 430 CB HIS+ 147-8.128-1.009 6.984 1.00 0.00 ATOM 431 1HB HIS+ 147-8.008-1.946 7.509 1.00 0.00 ATOM 432 2HB HIS+ 147-9.006-0.506 7.361 1.00 0.00 ATOM 433 QB HIS+ 147-8.507-1.226 7.435 1.00 0.00 ATOM 434 CG HIS+ 147-6.940-0.152 7.297 1.00 0.00 ATOM 435 ND1 HIS+ 147-7.024 1.211 7.490 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.636-0.476 7.476 1.00 0.00 ATOM 437 1HD HIS+ 147-7.843 1.753 7.421 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.825 1.689 7.777 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.965 0.686 7.776 1.00 0.00 ATOM 440 2HD HIS+ 147-5.201-1.464 7.389 1.00 0.00 ATOM 441 1HE HIS+ 147-5.588 2.725 7.977 1.00 0.00 ATOM 442 2HE HIS+ 147-4.029 0.745 8.068 1.00 0.00 ATOM 443 C HIS+ 147-7.783-2.696 5.177 1.00 0.00 ATOM 444 O HIS+ 147-6.620-2.848 4.812 1.00 0.00 ATOM 445 N LEU 148-8.626-3.710 5.338 1.00 0.00 ATOM 446 H LEU 148-9.537-3.529 5.643 1.00 0.00 ATOM 447 CA LEU 148-8.224-5.090 5.089 1.00 0.00 ATOM 448 HA LEU 148-7.288-5.258 5.601 1.00 0.00 ATOM 449 CB LEU 148-9. 275-6.050 5.657 1.00 0.00 ATOM 450 1HB LEU 148-10.245-5.742 5.297 1.00 0.00 ATOM 451 2HB LEU 148-9.265-5.964 6.734 1.00 0.00 ATOM 452 QB LEU 148-9.755-5.853 6.015 1.00 0.00 ATOM 453 CG LEU 148-9.076-7.521 5.291 1.00 0.00 ATOM 454 HG LEU 148-8.670-7.581 4.292 1.00 0.00 ATOM 455 QD1 LEU 148-7.856-8.341 6.463 1.00 0.00 ATOM 456 QD2 LEU 148-10.718-8.435 5.309 1.00 0.00 ATOM 457 CD1 LEU 148-8.089-8.183 6.239 1.00 0.00 ATOM 458 1HD1 LEU 148-7.106-8.184 5.792 1.00 0.00 ATOM 459 2HD1 LEU 148-8. 399-9.201 6.426 1.00 0.00 ATOM 460 3HD1 LEU 148-8.062-7.638 7.171 1.00 0.00 ATOM 461 CD2 LEU 148-10.404-8.259 5.305 1.00 0.00 ATOM 462 1HD2 LEU 148-10.223-9.324 5.314 1.00 0.00 ATOM 463 2HD2 LEU 148-10.971-7.998 4.425 1.00 0.00 ATOM 464 3HD2 LEU 148-10. 961-7.982 6.188 1.00 0.00 ATOM 465 QQD LEU 148-9.287-8.388 5.886 1.00 0.00 ATOM 466 C LEU 148-8.019-5.360 3.600 1.00 0.00 ATOM 467 O LEU 148-7.097-6.080 3.217 1.00 0.00 ATOM 468 N HIS+ 149-8.881-4.788 2.766 1.00 0.00 ATOM 469 H HIS+ 149-9. 598-4.227 3.127 1.00 0.00 ATOM 470 CA HIS+ 149-8.785-4.988 1.325 1.00 0.00 ATOM 471 HA HIS+ 149-8.830-6.051 1.143 1.00 0.00 ATOM 472 CB HIS+ 149-9.952-4.322 0. 603 1.00 0.00 ATOM 473 1HB HIS+ 149-9.574-3.548-0.052 1.00 0.00 ATOM 474 2HB HIS+ 149-10.615-3.873 1.329 1.00 0.00 ATOM 475 QB HIS+ 149-10.095-3.711 0.638 1.00 0.00 ATOM 476 CG HIS+ 149-10.751-5.278-0.227 1.00 0.00 ATOM 477 ND1 HIS+ 149-10.218-5. 985-1.283 1.00 0.00 ATOM 478 CD2 HIS+ 149-12.054-5.634-0.156 1.00 0.00 ATOM 479 1HD HIS+ 149-9.286-5.942-1.591 1.00 0.00 ATOM 480 CE1 HIS+ 149-11.162-6.734-1.827 1.00 0.00 ATOM 481 NE2 HIS+ 149-12.289-6.539-1.162 1.00 0. 00 ATOM 482 2HD HIS+ 149-12.783-5.262 0.553 1.00 0.00 ATOM 483 1HE HIS+ 149-11.035-7.393-2.674 1.00 0.00 ATOM 484 2HE HIS+ 149-13.179-6.801-1.483 1.00 0.00 ATOM 485 C HIS+ 149-7.463-4.467 0.784 1.00 0.00 ATOM 486 O HIS+ 149-6.715-5.213 0.158 1.00 0.00 ATOM 487 N TRP 150-7.175-3.193 1.032 1.00 0.00 ATOM 488 H TRP 150-7.815-2.645 1.538 1.00 0.00 ATOM 489 CA TRP 150-5. 925-2.589 0.566 1.00 0.00 ATOM 490 HA TRP 150-5.873-2.708-0.507 1.00 0.00

ATOM 491 CB TRP 150-5. 870-1.105 0.910 1.00 0.00 ATOM 492 1HB TRP 150-4.898-0.721 0.634 1.00 0.00 ATOM 493 2HB TRP 150-6. 002-0.988 1.975 1.00 0.00 ATOM 494 QB TRP 150-5.450-0.855 1.304 1.00 0.00 ATOM 495 CG TRP 150-6.903-0.268 0.229 1.00 0.00 ATOM 496 CD1 TRP 150-7. 296 0.981 0.600 1.00 0.00 ATOM 497 CD2 TRP 150-7. 670-0.603-0.935 1.00 0.00 ATOM 498 CE3 TRP 150-7. 735-1.718-1.775 1.00 0.00 ATOM 499 CE2 TRP 150-8.505 0.493-1.205 1.00 0.00 ATOM 500 NE1 TRP 150-8. 261 1.443-0.255 1.00 0.00 ATOM 501 HD TRP 150-6. 899 1. 517 1.450 1.00 0.00 ATOM 502 3HE TRP 150-7.111-2.581-1.605 1.00 0.00 ATOM 503 CZ3 TRP 150-8. 614-1.703-2.833 1.00 0.00 ATOM 504 CZ2 TRP 150-9.388 0.506-2.274 1.00 0.00 ATOM 505 1HE TRP 150-8. 704 2.314-0.194 1.00 0.00 ATOM 506 3HZ TRP 150-8.682-2.558-3.488 1.00 0.00 ATOM 507 CH2 TRP 150-9. 429-0.598-3.074 1.00 0.00 ATOM 508 2HZ TRP 150-10.026 1.354-2.478 1.00 0.00 ATOM 509 HH TRP 150-10.105-0.630-3.915 1.00 0.00 ATOM 510 C TRP 150-4.729-3.287 1.174 1.00 0.00 ATOM 511 O TRP 150-3.700-3.413 0.527 1.00 0.00 ATOM 512 N HIS+ 151-4.873-3.757 2.406 1.00 0.00 ATOM 513 H HIS+ 151-5.728-3.638 2.870 1.00 0.00 ATOM 514 CA HIS+ 151-3.792-4.469 3.069 1.00 0.00 ATOM 515 HA HIS+ 151-2.938-3.811 3.122 1.00 0.00 ATOM 516 CB HIS+ 151-4.213-4.885 4.488 1.00 0.00 ATOM 517 1HB HIS+ 151-5.080-5.528 4.419 1.00 0.00 ATOM 518 2HB HIS+ 151-4.476-4.001 5.048 1.00 0.00 ATOM 519 QB HIS+ 151-4.778-4.765 4.733 1.00 0.00 ATOM 520 CG HIS+ 151-3.157-5.622 5.266 1.00 0.00 ATOM 521 ND1 HIS+ 151-2. 758-5.253 6.532 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.430-6.724 4.955 1.00 0.00 ATOM 523 1HD HIS+ 151-3. 099-4. 486 7.041 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.835-6.095 6. 963 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.619-6.997 6.027 1.00 0.00 ATOM 526 2HD HIS+ 151-2.470-7.272 4.021 1.00 0.00 ATOM 527 1HE HIS+ 151-1.331-6.044 7.918 1.00 0.00 ATOM 528 2HE HIS+ 151-1.104-7.821 6.151 1.00 0.00 ATOM 529 C HIS+ 151-3.427-5.692 2.243 1.00 0.00 ATOM 530 O HIS+ 151-2.254-5.966 2.003 1.00 0.00 ATOM 531 N THR 152-4.447-6.414 1.806 1.00 0.00 ATOM 532 H THR 152-5. 360-6.136 2.028 1.00 0.00 ATOM 533 CA THR 152-4.247-7.601 0.999 1.00 0.00 ATOM 534 HA THR 152-3.513-8.219 1.496 1.00 0.00 ATOM 535 CB THR 152-5.556-8.383 0.871 1.00 0.00 ATOM 536 HB THR 152-6.210-7.863 0.184 1.00 0.00 ATOM 537 QG2 THR 152-5.325-10.130 0.234 1.00 0.00 ATOM 538 OG1 THR 152-6.207-8.473 2.128 1.00 0.00 ATOM 539 1HG THR 152-6.529-7.603 2.393 1.00 0.00 ATOM 540 CG2 THR 152-5.369-9.794 0.357 1.00 0.00 ATOM 541 1HG2 THR 152-6.242-10.090-0.207 1.00 0.00 ATOM 542 2HG2 THR 152-5.235-10.467 1.191 1.00 0.00 ATOM 543 3HG2 THR 152-4.499-9.833-0.282 1.00 0.00 ATOM 544 C THR 152-3.700-7.235-0.370 1.00 0.00 ATOM 545 O THR 152-2.710-7.810-0.787 1.00 0.00 ATOM 546 N VAL 153-4.330-6.269-1.048 1.00 0.00 ATOM 547 H VAL 153-5.112-5.833-0.644 1.00 0.00 ATOM 548 CA VAL 153-3.871-5.833-2.372 1.00 0.00 ATOM 549 HA VAL 153-3.938-6.677-3.040 1.00 0.00 ATOM 550 CB VAL 153-4.744-4.690-2.936 1.00 0.00 ATOM 551 HB VAL 153-4.610-3.818-2.314 1.00 0.00 ATOM 552 QG1 VAL 153-4.219-4.251-4.690 1.00 0.00 ATOM 553 QG2 VAL 153-6.562-5.170-2.903 1.00 0.00 ATOM 554 CG1 VAL 153-4.320-4.334-4.354 1.00 0.00 ATOM 555 1HG1 VAL 153-5.013-4.772-5.057 1.00 0.00 ATOM 556 2HG1 VAL 153-3.328-4.721-4.540 1.00 0.00 ATOM 557 3HG1 VAL 153-4.317-3.261-4.471 1.00 0.00 ATOM 558 CG2 VAL 153-6.215-5.077-2.909 1.00 0.00 ATOM 559 1HG2 VAL 153-6.345-6.026-3.411 1.00 0.00 ATOM 560 2HG2 VAL 153-6.795-4.320-3.414 1.00 0.00 ATOM 561 3HG2 VAL 153-6.545-5.163-1.884 1.00 0.00 ATOM 562 QQG VAL 153-5.391-4.711-3.797 1.00 0.00

ATOM 563 C VAL 153-2.417-5.385-2.308 1.00 0.00 ATOM 564 O VAL 153-1.595-5.761-3.137 1.00 0.00 ATOM 565 N ALA 154-2.107-4.599-1.299 1.00 0.00 ATOM 566 H ALA 154-2.810-4.343-0.658 1.00 0.00 ATOM 567 CA ALA 154-0.753-4.121-1.098 1.00 0.00 ATOM 568 HA ALA 154-0.441-3.587-1.984 1.00 0.00 ATOM 569 QB ALA 154-0.712-2.942 0.359 1.00 0.00 ATOM 570 CB ALA 154-0.720-3.168 0.080 1.00 0.00 ATOM 571 1HB ALA 154-1.722-2.827 0.296 1.00 0.00 ATOM 572 2HB ALA 154-0.094-2.321-0.162 1.00 0.00 ATOM 573 3HB ALA 154-0.319-3.678 0.943 1.00 0.00 ATOM 574 C ALA 154 0.195-5.289-0.851 1.00 0.00 ATOM 575 O ALA 154 1.268-5.380-1.451 1.00 0.00 ATOM 576 N LYS+ 155-0.212-6.175 0.051 1.00 0.00 ATOM 577 H LYS+ 155-1.078-6.034 0.495 1.00 0.00 ATOM 578 CA LYS+ 155 0.584-7.341 0.409 1.00 0.00 ATOM 579 HA LYS+ 155 1.555-6. 989 0.746 1.00 0.00 ATOM 580 CB LYS+ 155-0. 091-8.116 1.550 1.00 0.00 ATOM 581 1HB LYS+ 155-1.134-8.254 1.300 1.00 0.00 ATOM 582 2HB LYS+ 155-0.026-7.532 2.455 1.00 0.00 ATOM 583 QB LYS+ 155-0.580-7.893 1.877 1.00 0.00 ATOM 584 CG LYS+ 155 0.518-9.486 1.816 1.00 0.00 ATOM 585 1HG LYS+ 155 1.176-9.740 0.997 1.00 0.00 ATOM 586 2HG LYS+ 155-0.279-10.213 1.878 1.00 0.00 ATOM 587 QG LYS+ 155 0.448-9.977 1.437 1.00 0.00 ATOM 588 CD LYS+ 155 1.310-9.513 3.116 1.00 0.00 ATOM 589 1HD LYS+ 155 0.636-9.326 3.940 1.00 0.00 ATOM 590 2HD LYS+ 155 2.063-8.738 3.085 1.00 0.00 ATOM 591 QD LYS+ 155 1.349-9.032 3.512 1.00 0.00 ATOM 592 CE LYS+ 155 1.995-10.859 3.333 1.00 0.00 ATOM 593 1HE LYS+ 155 1.507-11.366 4.154 1.00 0.00 ATOM 594 2HE LYS+ 155 3.031-10.684 3.586 1.00 0.00 ATOM 595 QE LYS+ 155 2.269-11.025 3.870 1.00 0.00 ATOM 596 NZ LYS+ 155 1.933-11.726 2.119 1.00 0.00 ATOM 597 1HZ LYS+ 155 1.002-11.643 1.664 1.00 0.00 ATOM 598 2HZ LYS+ 155 2.092-12.720 2.378 1.00 0.00 ATOM 599 3HZ LYS+ 155 2.671-11.437 1.430 1.00 0.00 ATOM 600 QZ LYS+ 155 1.922-11.933 1.824 1.00 0.00 ATOM 601 C LYS+ 155 0.796-8.261-0.785 1.00 0.00 ATOM 602 O LYS+ 155 1. 923-8. 674-1.032 1.00 0.00 ATOM 603 N GLU 156-0.274-8.597-1.511 1.00 0.00 ATOM 604 H GLU 156-1.165-8.249-1.261 1.00 0.00 ATOM 605 CA GLU 156-0.143-9.487-2.665 1.00 0.00 ATOM 606 HA GLU 156 0.303-10.405-2.308 1.00 0.00 ATOM 607 CB GLU 156-1.500-9.828-3.309 1.00 0.00 ATOM 608 1HB GLU 156-2.012-10.541-2.680 1.00 0.00 ATOM 609 2HB GLU 156-1.317-10.285-4.272 1.00 0.00 ATOM 610 QB GLU 156-1.665-10.413-3.476 1.00 0.00 ATOM 611 CG GLU 156-2.420-8.641-3.527 1.00 0.00 ATOM 612 1HG GLU 156-1. 952-7.758-3.115 1.00 0.00 ATOM 613 2HG GLU 156-3.351-8.825-3.013 1.00 0.00 ATOM 614 QG GLU 156-2.652-8.292-3.064 1.00 0.00 ATOM 615 CD GLU 156-2.723-8.388-4.988 1.00 0.00 ATOM 616 OE1 GLU 156-1.841-7.855-5.692 1.00 0.00 ATOM 617 OE2 GLU 156-3.847-8.712-5.422 1.00 0.00 ATOM 618 C GLU 156 0.793-8.890-3.707 1.00 0.00 ATOM 619 O GLU 156 1.680-9.570-4.192 1.00 0.00 ATOM 620 N THR 157 0.602-7.618-4.037 1.00 0.00 ATOM 621 H THR 157-0.128-7.116-3.611 1.00 0.00 ATOM 622 CA THR 157 1.447-6.950-5.022 1.00 0.00 ATOM 623 HA THR 157 1.289-7.445-5.969 1.00 0.00 ATOM 624 CB THR 157 1.030-5.478-5.155 1.00 0.00 ATOM 625 HB THR 157 1.007-5.033-4.171 1.00 0.00 ATOM 626 QG2 THR 157 2.183-4.454-6.222 1.00 0.00 ATOM 627 OG1 THR 157-0.266-5.372-5.719 1.00 0.00 ATOM 628 1HG THR 157-0.769-6.187-5.546 1. 00 0. 00 ATOM 629 CG2 THR 157 1.962-4.650-6.017 1.00 0.00 ATOM 630 1HG2 THR 157 2.418-3.879-5.415 1.00 0.00 ATOM 631 2HG2 THR 157 1.400-4.196-6.819 1.00 0.00 ATOM 632 3HG2 THR 157 2.731-5.287-6.431 1. 00 0. 00 ATOM 633 C THR 157 2.934-7.067-4.661 1.00 0.00 ATOM 634 O THR 157 3.786-7.255-5.533 1.00 0.00

ATOM 635 N CYS 158 3.247-6.960-3.377 1.00 0.00 ATOM 636 H CYS 158 2.532-6.810-2.718 1.00 0.00 ATOM 637 CA CYS 158 4.630-7.062-2.928 1.00 0.00 ATOM 638 HA CYS 158 5.252-6.593-3.676 1.00 0.00 ATOM 639 CB CYS 158 4.807-6.316-1.606 1.00 0.00 ATOM 640 1HB CYS 158 5.673-6.693-1.095 1.00 0.00 ATOM 641 2HB CYS 158 3.940-6.490-0.993 1.00 0.00 ATOM 642 QB CYS 158 4.806-6.592-1.044 1.00 0.00 ATOM 643 SG CYS 158 5.002-4.506-1.802 1.00 0.00 ATOM 644 C CYS 158 5.066-8.525-2.785 1.00 0.00 ATOM 645 O CYS 158 6.167-8.889-3.200 1.00 0.00 ATOM 646 N SER 159 4.210-9.351-2.183 1.00 0.00 ATOM 647 H SER 159 3.354-8.995-1.859 1.00 0.00 ATOM 648 CA SER 159 4.511-10.767-1.964 1.00 0.00 ATOM 649 HA SER 159 5.497-10.818-1.527 1.00 0.00 ATOM 650 CB SER 159 3.516-11.376-0.979 1.00 0.00 ATOM 651 1HB SER 159 3.507-12.450-1.102 1.00 0.00 ATOM 652 2HB SER 159 2.530-10.982-1.178 1.00 0.00 ATOM 653 QB SER 159 3.018-11.716-1.140 1.00 0.00 ATOM 654 OG SER 159 3.878-11.067 0.363 1.00 0.00 ATOM 655 HG SER 159 4.840-10.987 0.418 1.00 0.00 ATOM 656 C SER 159 4.525-11.588-3.255 1.00 0.00 ATOM 657 O SER 159 5.266-12.564-3.340 1.00 0.00 ATOM 658 N GLU 160 3.723-11.202-4.251 1.00 0.00 ATOM 659 H GLU 160 3.145-10.413-4.136 1.00 0.00 ATOM 660 CA GLU 160 3.691-11.931-5.521 1.00 0.00 ATOM 661 HA GLU 160 3.536-12.978-5.298 1.00 0.00 ATOM 662 CB GLU 160 2.553-11.429-6.415 1.00 0.00 ATOM 663 1HB GLU 160 2.925-10.631-7.038 1.00 0.00 ATOM 664 2HB GLU 160 1.760-11.048-5.788 1.00 0.00 ATOM 665 QB GLU 160 2.342-10.840-6.413 1.00 0.00 ATOM 666 CG GLU 160 1.967-12.506-7.317 1.00 0.00 ATOM 667 1HG GLU 160 2.774-13.011-7.826 1.00 0.00 ATOM 668 2HG GLU 160 1.322-12.036-8.045 1.00 0.00 ATOM 669 QG GLU 160 2.048-12.524-7.936 1.00 0.00 ATOM 670 CD GLU 160 1.156-13.537-6.553 1.00 0.00 ATOM 671 OE1 GLU 160 0.713-14.521-7.178 1.00 0.00 ATOM 672 OE2 GLU 160 0.966-13.362-5.329 1.00 0.00 ATOM 673 C GLU 160 5.035-11.769-6.214 1.00 0.00 ATOM 674 O GLU 160 5.435-12.569-7.063 1.00 0.00 ATOM 675 N LYS+ 161 5.752-10.739-5.795 1.00 0.00 ATOM 676 H LYS+ 161 5.387-10.167-5.089 1.00 0.00 ATOM 677 CA LYS+ 161 7.073-10.469-6.300 1.00 0.00 ATOM 678 HA LYS+ 161 7.181-10.995-7.236 1.00 0.00 ATOM 679 CB LYS+ 161 7.289-8.968-6.526 1.00 0.00 ATOM 680 1HB LYS+ 161 7.684-8.535-5.617 1.00 0.00 ATOM 681 2HB LYS+ 161 6.338-8.508-6.745 1.00 0.00 ATOM 682 QB LYS+ 161 7.011-8.522-6.181 1.00 0.00 ATOM 683 CG LYS+ 161 8.255-8.650-7.666 1.00 0.00 ATOM 684 1HG LYS+ 161 9.268-8.774-7.310 1.00 0.00 ATOM 685 2HG LYS+ 161 8.105-7.626-7.974 1.00 0.00 ATOM 686 QG LYS+ 161 8.686-8.200-7.642 1.00 0. 00 ATOM 687 CD LYS+ 161 8. 035-9.562-8.869 1.00 0.00 ATOM 688 1HD LYS+ 161 8.119-8.975-9.773 1.00 0.00 ATOM 689 2HD LYS+ 161 7.043-9.987-8.808 1. 00 0. 00 ATOM 690 QD LYS+ 161 7.581-9.481-9.291 1. 00 0. 00 ATOM 691 CE LYS+ 161 9.053-10.699-8.920 1.00 0.00 ATOM 692 1HE LYS+ 161 9.100-11.076-9.932 1.00 0.00 ATOM 693 2HE LYS+ 161 8.723-11.488-8.259 1. 00 0. 00 ATOM 694 QE LYS+ 161 8.911-11.282-9. 096 1.00 0.00 ATOM 695 NZ LYS+ 161 10.415-10.256-8.501 1. 00 0. 00 ATOM 696 1HZ LYS+ 161 11.140-10.826-8.982 1. 00 0. 00 ATOM 697 2HZ LYS+ 161 10. 535-10. 370-7.466 1.00 0.00 ATOM 698 3HZ LYS+ 161 10.559-9.256-8.745 1. 00 0. 00 ATOM 699 QZ LYS+ 161 10.745-10. 151-8.398 1. 00 0.00 ATOM 700 C LYS+ 161 8.080-11.021-5.303 1. 00 0. 00 ATOM 701 0 LYS+ 161 7.912-12.121-4.792 1.00 0.00 ATOM 702 N SER 162 9.121-10.268-5.022 1.00 0.00 ATOM 703 H SER 162 9.218-9.396-5.446 1. 00 0.00 ATOM 704 CA SER 162 10.119-10.719-4.079 1. 00 0.00 ATOM 705 HA SER 162 9.823-11.696-3.731 1.00 0.00 ATOM 706 CB SER 162 11.483-10.830-4.763 l. oo 0. 00

ATOM 707 1HB SER 162 11.690-11.869-4.976 1.00 0.00 ATOM 708 2HB SER 162 12.244-10.444-4.097 1.00 0.00 ATOM 709 QB SER 162 11.967-11.157-4.537 1.00 0.00 ATOM 710 OG SER 162 11.516-10.089-5.982 1.00 0.00 ATOM 711 HG SER 162 12.293-9.516-5.975 1.00 0.00 ATOM 712 C SER 162 10. 206-9.780-2.881 1.00 0.00 ATOM 713 O SER 162 11.295-9.374-2.497 1.00 0.00 ATOM 714 N THR 163 9. 063-9.419-2.292 1.00 0.00 ATOM 715 H THR 163 8.205-9.757-2.637 1.00 0.00 ATOM 716 CA THR 163 9.069-8.530-1.135 1.00 0.00 ATOM 717 HA THR 163 10.013-8.666-0.624 1.00 0.00 ATOM 718 CB THR 163 8.947-7.062-1.553 1.00 0.00 ATOM 719 HB THR 163 8.848-6.465-0.652 1.00 0.00 ATOM 720 QG2 THR 163 10. 413-6.405-2.515 1.00 0.00 ATOM 721 OG1 THR 163 7.799-6.861-2.354 1.00 0.00 ATOM 722 1HG THR 163 7.519-7.707-2.734 1.00 0.00 ATOM 723 CG2 THR 163 10.131-6.530-2.330 1.00 0.00 ATOM 724 1HG2 THR 163 9.789-6.106-3.262 1.00 0.00 ATOM 725 2HG2 THR 163 10.820-7.339-2.532 1.00 0.00 ATOM 726 3HG2 THR 163 10.630-5.769-1.749 1.00 0.00 ATOM 727 C THR 163 7.941-8.868-0.160 1.00 0.00 ATOM 728 O THR 163 6. 989-9.573-0.497 1.00 0.00 ATOM 729 N ASN 164 8.052-8.343 1.050 1.00 0.00 ATOM 730 H ASN 164 8.837-7.786 1.252 1.00 0.00 ATOM 731 CA ASN 164 7.045-8.563 2.092 1.00 0.00 ATOM 732 HA ASN 164 6.186-9.034 1.628 1.00 0.00 ATOM 733 CB ASN 164 7.593-9.479 3.193 1.00 0.00 ATOM 734 1HB ASN 164 7.389-10.506 2.932 1.00 0.00 ATOM 735 2HB ASN 164 7.101-9.245 4.126 1.00 0.00 ATOM 736 QB ASN 164 7.245-9.876 3.529 1.00 0.00 ATOM 737 CG ASN 164 9.090-9.324 3.392 1.00 0.00 ATOM 738 OD1 ASN 164 9.798-10.300 3.593 1.00 0.00 ATOM 739 ND2 ASN 164 9.571-8.089 3.357 1.00 0.00 ATOM 740 1HD2 ASN 164 8.939-7.351 3.226 1.00 0.00 ATOM 741 2HD2 ASN 164 10.538-7.968 3.412 1.00 0.00 ATOM 742 QD2 ASN 164 9.738-7.660 3.319 1.00 0.00 ATOM 743 C ASN 164 6.614-7.237 2.712 1.00 0.00 ATOM 744 O ASN 164 7.455-6.407 3.053 1.00 0.00 ATOM 745 N LEU 165 5.308-7.040 2.853 1.00 0.00 ATOM 746 H LEU 165 4.690-7.737 2.563 1.00 0.00 ATOM 747 CA LEU 165 4.770-5.809 3.435 1.00 0.00 ATOM 748 HA LEU 165 5.206-4.967 2.915 1.00 0.00 ATOM 749 CB LEU 165 3.250-5.756 3.281 1.00 0.00 ATOM 750 1HB LEU 165 2.809-5.659 4.261 1.00 0.00 ATOM 751 2HB LEU 165 2.916-6.684 2.842 1.00 0.00 ATOM 752 QB LEU 165 2.862-6.172 3.551 1.00 0.00 ATOM 753 CG LEU 165 2.736-4.614 2.431 1.00 0.00 ATOM 754 HG LEU 165 3.207-3.693 2.745 1.00 0.00 ATOM 755 QD1 LEU 165 3.172-4.912 0.636 1.00 0.00 ATOM 756 QD2 LEU 165 0.880-4.428 2.649 1.00 0.00 ATOM 757 CD1 LEU 165 3.089-4.855 0.983 1.00 0.00 ATOM 758 1HD1 LEU 165 3.829-4.135 0.667 1.00 0.00 ATOM 759 2HD1 LEU 165 2.202-4.749 0.374 1.00 0.00 ATOM 760 3HD1 LEU 165 3.485-5.852 0.869 1.00 0.00 ATOM 761 CD2 LEU 165 1.236-4.464 2.608 1.00 0.00 ATOM 762 1HD2 LEU 165 0.986-4.552 3.655 1.00 0.00 ATOM 763 2HD2 LEU 165 0.728-5.237 2.050 1.00 0.00 ATOM 764 3HD2 LEU 165 0.925-3.495 2.244 1.00 0.00 ATOM 765 QQD LEU 165 2.026-4.670 1.643 1.00 0.00 ATOM 766 C LEU 165 5.117-5.696 4.905 1.00 0.00 ATOM 767 O LEU 165 4.777-6.569 5.700 1.00 0.00 ATOM 768 N HIS+ 166 5.780-4.609 5.252 1.00 0.00 ATOM 769 H HIS+ 166 6.013-3.947 4.566 1.00 0.00 ATOM 770 CA HIS+ 166 6.162-4.358 6.626 1.00 0.00 ATOM 771 HA HIS+ 166 5.917-5.236 7.206 1.00 0.00 ATOM 772 CB HIS+ 166 7.671-4.102 6.714 1.00 0.00 ATOM 773 1HB HIS+ 166 7.906-3.202 6.162 1.00 0.00 ATOM 774 2HB HIS+ 166 8.197-4.934 6.275 1.00 0.00 ATOM 775 QB HIS+ 166 8.051-4.068 6. 218 1.00 0.00 ATOM 776 CG HIS+ 166 8.175-3.926 8.112 1.00 0.00 ATOM 777 ND1 HIS+ 166 8.253-4.953 9.027 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.617-2.821 8.749 1.00 0.00

ATOM 779 1HD HIS+ 166 7.996-5.886 8.866 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.723-4.483 10.170 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.952-3.187 10.026 1.00 0.00 ATOM 782 2HD HIS+ 166 8.678-1.822 8.329 1.00 0.00 ATOM 783 1HE HIS+ 166 8.890-5.058 11.069 1.00 0.00 ATOM 784 2HE HIS+ 166 9.101-2.559 10.764 1.00 0.00 ATOM 785 C HIS+ 166 5.379-3.167 7.175 1.00 0.00 ATOM 786 O HIS+ 166 4.763-3.255 8.237 1.00 0.00 ATOM 787 N ASP 167 5.403-2.057 6.438 1.00 0.00 ATOM 788 H ASP 167 5.908-2.053 5.596 1.00 0.00 ATOM 789 CA ASP 167 4.693-0.845 6.858 1.00 0.00 ATOM 790 HA ASP 167 4.193-1.066 7.789 1.00 0.00 ATOM 791 CB ASP 167 5.667 0.321 7.086 1.00 0.00 ATOM 792 1HB ASP 167 5.260 0.971 7.847 1.00 0.00 ATOM 793 2HB ASP 167 5.769 0.878 6.167 1.00 0.00 ATOM 794 QB ASP 167 5.514 0.924 7.007 1.00 0.00 ATOM 795 CG ASP 167 7.048-0.121 7.526 1.00 0.00 ATOM 796 OD1 ASP 167 7.333-0.052 8.739 1.00 0.00 ATOM 797 OD2 ASP 167 7.849-0.530 6.658 1.00 0.00 ATOM 798 C ASP 167 3.648-0.428 5. 826 1.00 0.00 ATOM 799 O ASP 167 3.948 0.292 4.877 1.00 0.00 ATOM 800 N TYR 168 2.424-0.889 6.017 1.00 0.00 ATOM 801 H TYR 168 2.252-1.460 6.794 1.00 0.00 ATOM 802 CA TYR 168 1.316-0.570 5.115 1.00 0.00 ATOM 803 HA TYR 168 1.727-0.344 4.133 1.00 0.00 ATOM 804 CB TYR 168 0.379-1.776 5.001 1.00 0.00 ATOM 805 1HB TYR 168 0.802-2.489 4.312 1.00 0.00 ATOM 806 2HB TYR 168-0.580-1.445 4.628 1.00 0.00 ATOM 807 QB TYR 168 0.111-1.967 4.470 1.00 0.00 ATOM 808 QD TYR 168 0. 124-2.558 6.479 1.00 0.00 ATOM 809 QE TYR 168-0. 239-3.674 8.637 1.00 0.00 ATOM 810 QR TYR 168-0.057-3.116 7.558 1.00 0.00 ATOM 811 CG TYR 168 0.149-2.478 6.324 1.00 0.00 ATOM 812 CD1 TYR 168 0.994-3.495 6.754 1.00 0.00 ATOM 813 1HD TYR 168 1.821-3.792 6.126 1.00 0.00 ATOM 814 CE1 TYR 168 0.794-4.123 7.967 1.00 0.00 ATOM 815 1HE TYR 168 1.463-4.910 8.283 1.00 0.00 ATOM 816 CZ TYR 168-0.261-3.741 8.768 1.00 0.00 ATOM 817 CE2 TYR 168-1.114-2.737 8.364 1.00 0.00 ATOM 818 2HE TYR 168-1.940-2.437 8.992 1.00 0.00 ATOM 819 CD2 TYR 168-0.906-2.111 7.150 1.00 0.00 ATOM 820 2HD TYR 168-1.572-1.324 6.832 1.00 0.00 ATOM 821 OH TYR 168-0.466-4.366 9.973 1.00 0.00 ATOM 822 HH TYR 168 0.241-4.129 10.582 1.00 0.00 ATOM 823 C TYR 168 0.528 0.643 5.608 1.00 0.00 ATOM 824 O TYR 168 0.465 0.912 6.807 1.00 0.00 ATOM 825 N GLY 169-0.094 1.344 4.675 1.00 0.00 ATOM 826 H GLY 169-0.020 1.064 3.738 1.00 0.00 ATOM 827 CA GLY 169-0.896 2.504 5.003 1.00 0.00 ATOM 828 1HA GLY 169-0.272 3.387 4.992 1.00 0.00 ATOM 829 2HA GLY 169-1.319 2.378 5.989 1.00 0.00 ATOM 830 QA GLY 169-0.796 2.882 5.490 1.00 0.00 ATOM 831 C GLY 169-2.005 2.669 3.994 1.00 0.00 ATOM 832 O GLY 169-1.893 2.168 2.878 1.00 0.00 ATOM 833 N MET 170-3.078 3.349 4.364 1.00 0.00 ATOM 834 H MET 170-3.124 3.727 5.267 1.00 0. 00 ATOM 835 CA MET 170-4.197 3.547 3.445 1. 00 0. 00 ATOM 836 HA MET 170-3.844 3.345 2.436 1.00 0.00 ATOM 837 CB MET 170-5.364 2.604 3.778 1.00 0.00 ATOM 838 1HB MET 170-5.889 2.371 2.862 1.00 0.00 ATOM 839 2HB MET 170-6.040 3.116 4.447 1.00 0.00 ATOM 840 QB MET 170-5.965 2.743 3.654 1.00 0.00 ATOM 841 CG MET 170-4.948 1.297 4.434 1.00 0.00 ATOM 842 1HG MET 170-5.825 0.830 4.857 1.00 0.00 ATOM 843 2HG MET 170-4.247 1.517 5.223 1.00 0.00 ATOM 844 QG MET 170-5.036 1.173 5.040 1. 00 0. 00 ATOM 845 SD MET 170-4.176 0.144 3.290 1. oo 0. 00 ATOM 846 QE MET 170-3.281-1.253 4.654 1.00 0.00 ATOM 847 CE MET 170-3. 430-1.019 4.426 1.00 0.00 ATOM 848 1HE MET 170-4.147-1.287 5.188 1.00 0.00 ATOM 849 2HE MET 170-2.565-0.567 4.887 1.00 0.00 ATOM 850 3HE MET 170-3.130-1.905 3.887 1. 00 0. 00

ATOM 851 C MET 170-4.681 4.988 3.522 1.00 0.00 ATOM 852 O MET 170-5.088 5.454 4.587 1.00 0.00 ATOM 853 N LEU 171-4.630 5.691 2.401 1.00 0.00 ATOM 854 H LEU 171-4.291 5.267 1.584 1.00 0.00 ATOM 855 CA LEU 171-5.057 7.082 2.358 1.00 0.00 ATOM 856 HA LEU 171-5.339 7.367 3.360 1.00 0.00 ATOM 857 CB LEU 171-3.907 7.980 1.894 1.00 0.00 ATOM 858 1HB LEU 171-3.993 8.928 2.402 1.00 0.00 ATOM 859 2HB LEU 171-4.018 8.151 0.831 1.00 0.00 ATOM 860 QB LEU 171-4.006 8.539 1. 616 1.00 0.00 ATOM 861 CG LEU 171-2.503 7.430 2.146 1.00 0.00 ATOM 862 HG LEU 171-2. 565 6.591 2.825 1.00 0.00 ATOM 863 QD1 LEU 171-1.736 6.826 0.540 1.00 0.00 ATOM 864 QD2 LEU 171-1.419 8.743 2.940 1.00 0.00 ATOM 865 CD1 LEU 171-1.883 6.941 0.848 1.00 0.00 ATOM 866 1HD1 LEU 171-2.289 5.973 0.596 1.00 0.00 ATOM 867 2HD1 LEU 171-0.813 6.862 0.969 1.00 0.00 ATOM 868 3HD1 LEU 171-2. 106 7.643 0.056 1.00 0.00 ATOM 869 CD2 LEU 171-1.627 8.492 2.788 1.00 0.00 ATOM 870 1HD2 LEU 171-1.613 9.373 2.163 1.00 0.00 ATOM 871 2HD2 LEU 171-0.622 8.109 2.899 1.00 0.00 ATOM 872 3HD2 LEU 171-2.023 8.746 3.760 1.00 0.00 ATOM 873 QQD LEU 171-1.578 7.784 1.740 1.00 0.00 ATOM 874 C LEU 171-6.259 7.273 1.439 1.00 0.00 ATOM 875 O LEU 171-6.974 6.318 1.130 1.00 0.00 ATOM 876 N LEU 172-6.459 8.523 1.010 1.00 0.00 ATOM 877 H LEU 172-5.834 9.219 1.303 1.00 0.00 ATOM 878 CA LEU 172-7.560 8.909 0.119 1.00 0.00 ATOM 879 HA LEU 172-7.641 9.985 0.156 1.00 0.00 ATOM 880 CB LEU 172-7.252 8.499-1.323 1.00 0.00 ATOM 881 1HB LEU 172-8.032 7.830-1.655 1.00 0.00 ATOM 882 2HB LEU 172-6.314 7.963-1.332 1.00 0.00 ATOM 883 QB LEU 172-7.173 7.896-1.494 1.00 0.00 ATOM 884 CG LEU 172-7.154 9.652-2.326 1.00 0.00 ATOM 885 HG LEU 172-6.234 10.193-2.152 1.00 0.00 ATOM 886 QD1 LEU 172-7. 111 8.991-4.083 1.00 0.00 ATOM 887 QD2 LEU 172-8.587 10.852-2.115 1.00 0.00 ATOM 888 CD1 LEU 172-7.120 9.117-3.746 1.00 0.00 ATOM 889 1HD1 LEU 172-7.448 8.089-3.752 1.00 0.00 ATOM 890 2HD1 LEU 172-6.111 9.175-4.127 1.00 0.00 ATOM 891 3HD1 LEU 172-7.775 9.709-4.369 1.00 0.00 ATOM 892 CD2 LEU 172-8.313 10.622-2.155 1.00 0.00 ATOM 893 1HD2 LEU 172-8.669 10.930-3.127 1.00 0.00 ATOM 894 2HD2 LEU 172-7.978 11.488-1.604 1.00 0.00 ATOM 895 3HD2 LEU 172-9.113 10.138-1.614 1.00 0.00 ATOM 896 QQD LEU 172-7.849 9.921-3.099 1.00 0.00 ATOM 897 C LEU 172-8.903 8.312 0.545 1.00 0.00 ATOM 898 O LEU 172-9.507 7.545-0.202 1.00 0.00 ATOM 899 N PRO 173-9.410 8.660 1.741 1.00 0.00 ATOM 900 CD PRO 173-8.799 9.579 2.711 1.00 0.00 ATOM 901 CA PRO 173-10.694 8. 145 2.218 1.00 0.00 ATOM 902 HA PRO 173-10.721 7.065 2.194 1.00 0.00 ATOM 903 CB PRO 173-10.779 8.637 3.671 1.00 0.00 ATOM 904 1HB PRO 173-11.069 7.817 4.312 1.00 0.00 ATOM 905 2HB PRO 173-11.513 9.427 3.739 1.00 0.00 ATOM 906 QB PRO 173-11.291 8.622 4.025 1.00 0.00 ATOM 907 CG PRO 173-9.410 9.135 4.009 1.00 0.00 ATOM 908 1HG PRO 173-8.827 8.338 4.445 1.00 0.00 ATOM 909 2HG PRO 173-9.482 9.967 4.694 1.00 0.00 ATOM 910 QG PRO 173-9.155 9.152 4.569 1.00 0.00 ATOM 911 1HD PRO 173-7.726 9.459 2.735 1.00 0.00 ATOM 912 2HD PRO 173-9.065 10.604 2.497 1.00 0.00 ATOM 913 QD PRO 173-8.396 10.031 2.616 1.00 0.00 ATOM 914 C PRO 173-11.858 8.700 1.402 1.00 0.00 ATOM 915 O PRO 173-12.178 9.884 1.489 1.00 0.00 ATOM 916 N CYS 174-12.483 7.847 0.600 1.00 0.00 ATOM 917 H CYS 174-12.184 6.915 0.562 1.00 0.00 ATOM 918 CA CYS 174-13.604 8.278-0.229 1.00 0.00 ATOM 919 HA CYS 174-13.548 9.354-0.313 1.00 0.00 ATOM 920 CB CYS 174-13.510 7.669-1.629 1.00 0.00 ATOM 921 1HB CYS 174-12.483 7.392-1.820 1.00 0. 00 ATOM 922 2HB CYS 174-13. 815 8.411-2.351 1.00 0.00

ATOM 923 QB CYS 174-13.149 7.901-2.086 1.00 0.00 ATOM 924 SG CYS 174-14.542 6.190-1.896 1.00 0.00 ATOM 925 C CYS 174-14.930 7.918 0.423 1.00 0.00 ATOM 926 O CYS 174-15.988 8.386 0.006 1.00 0.00 ATOM 927 N GLY 175-14.864 7.097 1.457 1.00 0.00 ATOM 928 H GLY 175-13.989 6.766 1.755 1.00 0.00 ATOM 929 CA GLY 175-16.058 6.701 2.165 1.00 0.00 ATOM 930 1HA GLY 175-16.290 5.675 1.925 1.00 0.00 ATOM 931 2HA GLY 175-16.878 7.334 1.854 1.00 0.00 ATOM 932 QA GLY 175-16.584 6.504 1.889 1.00 0.00 ATOM 933 C GLY 175-15.868 6.829 3.655 1.00 0.00 ATOM 934 O GLY 175-14.768 7.138 4.109 1.00 0.00 ATOM 935 N ILE 176-16.925 6.589 4.420 1.00 0.00 ATOM 936 H ILE 176-17. 775 6.343 4.003 1.00 0.00 ATOM 937 CA ILE 176-16.842 6.679 5.872 1.00 0.00 ATOM 938 HA ILE 176-16.457 7.660 6.117 1.00 0.00 ATOM 939 CB ILE 176-18.240 6.527 6.530 1.00 0.00 ATOM 940 HB ILE 176-18.800 7.429 6.327 1.00 0.00 ATOM 941 QG2 ILE 176-19.191 5.083 5.784 1.00 0.00 ATOM 942 CG2 ILE 176-19.009 5.359 5.925 1.00 0.00 ATOM 943 1HG2 ILE 176-18.361 4.497 5.861 1.00 0.00 ATOM 944 2HG2 ILE 176-19.355 5.626 4.939 1.00 0.00 ATOM 945 3HG2 ILE 176-19.856 5.125 6.553 1.00 0.00 ATOM 946 CG1 ILE 176-18. 118 6.357 8.046 1.00 0.00 ATOM 947 1HG1 ILE 176-17.417 7.085 8.429 1.00 0.00 ATOM 948 2HG1 ILE 176-17.751 5.364 8.261 1.00 0.00 ATOM 949 QG1 ILE 176-17.584 6.224 8.345 1.00 0.00 ATOM 950 QD1 ILE 176-19.739 6.579 8.955 1.00 0.00 ATOM 951 CD1 ILE 176-19.427 6.537 8.781 1.00 0.00 ATOM 952 1HD1 ILE 176-20.226 6.093 8.205 1.00 0.00 ATOM 953 2HD1 ILE 176-19.623 7.590 8.916 1.00 0.00 ATOM 954 3HD1 ILE 176-19.368 6.055 9.745 1.00 0.00 ATOM 955 C ILE 176-15.871 5.624 6.415 1.00 0.00 ATOM 956 O ILE 176-15.115 5.886 7.350 1.00 0.00 ATOM 957 N ASP 177-15.886 4.444 5.799 1.00 0.00 ATOM 958 H ASP 177-16.499 4.310 5.051 1.00 0.00 ATOM 959 CA ASP 177-15.003 3.351 6.193 1.00 0.00 ATOM 960 HA ASP 177-14.246 3.754 6.851 1.00 0.00 ATOM 961 CB ASP 177-15.788 2.265 6.941 1.00 0.00 ATOM 962 1HB ASP 177-16.431 1.751 6.243 1.00 0.00 ATOM 963 2HB ASP 177-16.391 2.728 7.706 1.00 0.00 ATOM 964 QB ASP 177-16.411 2.239 6.974 1.00 0.00 ATOM 965 CG ASP 177-14.884 1.241 7.602 1.00 0.00 ATOM 966 OD1 ASP 177-15.167 0.031 7.471 1.00 0.00 ATOM 967 OD2 ASP 177-13.890 1.646 8.239 1.00 0.00 ATOM 968 C ASP 177-14.321 2.747 4.962 1.00 0.00 ATOM 969 O ASP 177-14.163 1.530 4.845 1.00 0.00 ATOM 970 N LYS+ 178-13.914 3.599 4.032 1.00 0.00 ATOM 971 H LYS+ 178-14.054 4.562 4.162 1.00 0.00 ATOM 972 CA LYS+ 178-13.250 3.124 2.825 1.00 0.00 ATOM 973 HA LYS+ 178-12.758 2.196 3.079 1.00 0.00 ATOM 974 CB LYS+ 178-14.255 2.851 1.704 1.00 0.00 ATOM 975 1HB LYS+ 178-13.755 2.960 0.753 1.00 0.00 ATOM 976 2HB LYS+ 178-15.047 3.572 1.767 1.00 0.00 ATOM 977 QB LYS+ 178-14.401 3.266 1.260 1.00 0.00 ATOM 978 CG LYS+ 178-14.857 1.450 1.775 1.00 0.00 ATOM 979 1HG LYS+ 178-15. 136 1.246 2.800 1.00 0.00 ATOM 980 2HG LYS+ 178-14.110 0.737 1.459 1.00 0.00 ATOM 981 QG LYS+ 178-14.623 0.991 2.129 1.00 0.00 ATOM 982 CD LYS+ 178-16.084 1.295 0.887 1.00 0.00 ATOM 983 1HD LYS+ 178-15.976 1.939 0.026 1.00 0.00 ATOM 984 2HD LYS+ 178-16.961 1.585 1.447 1.00 0.00 ATOM 985 QD LYS+ 178-16.469 1.762 0.736 1.00 0.00 ATOM 986 CE LYS+ 178-16.257-0.147 0.407 1.00 0.00 ATOM 987 1HE LYS+ 178-15.760-0.255-0.549 1.00 0.00 ATOM 988 2HE LYS+ 178-17.311-0.346 0.283 1.00 0.00 ATOM 989 QE LYS+ 178-16.536-0.301-0.133 1.00 0.00 ATOM 990 NZ LYS+ 178-15.687-1.144 1.362 1.00 0.00 ATOM 991 1HZ LYS+ 178-16.448-1.624 1.879 1.00 0.00 ATOM 992 2HZ LYS+ 178-15. 059-0.679 2.045 1.00 0.00 ATOM 993 3HZ LYS+ 178-15.133-1.870 0.836 1. 00 0. 00 ATOM 994 QZ LYS+ 178-15.547-1.391 1.586 1. 00 0. 00

ATOM 995 C LYS+ 178-12.183 4.101 2.373 1.00 0.00 ATOM 996 0 LYS+ 178-12.265 5.303 2.628 1.00 0.00 ATOM 997 N PHE 179-11.170 3.563 1.719 1.00 0.00 ATOM 998 H PHE 179-11.172 2.596 1.560 1.00 0.00 ATOM 999 CA PHE 179-10.047 4.355 1.251 1.00 0.00 ATOM 1000 HA PHE 179-10.269 5.395 1.430 1.00 0.00 ATOM 1001 CB PHE 179-8. 780 3.974 2.016 1.00 0.00 ATOM 1002 1HB PHE 179-8. 021 4.697 1.797 1.00 0.00 ATOM 1003 2HB PHE 179-8.442 3.008 1.676 1.00 0.00 ATOM 1004 QB PHE 179-8.232 3.852 1.736 1.00 0.00 ATOM 1005 QD PHE 179-8.972 3.904 3.675 1.00 0.00 ATOM 1006 QE PHE 179-9.257 3.808 6.117 1.00 0.00 ATOM 1007 QR PHE 179-9.172 3.837 5.385 1.00 0.00 ATOM 1008 CG PHE 179-8.952 3.911 3.509 1.00 0.00 ATOM 1009 CD1 PHE 179-8.684 5.019 4.295 1.00 0.00 ATOM 1010 1HD PHE 179-8.348 5.933 3.827 1.00 0.00 ATOM 1011 CE1 PHE 179-8.842 4.968 5.667 1.00 0.00 ATOM 1012 1HE PHE 179-8.630 5.840 6.269 1.00 0.00 ATOM 1013 CZ PHE 179-9.273 3.802 6.269 1.00 0.00 ATOM 1014 HZ PHE 179-9.400 3.762 7.342 1.00 0.00 ATOM 1015 CE2 PHE 179-9.544 2.689 5.497 1.00 0.00 ATOM 1016 2HE PHE 179-9.884 1.777 5.965 1.00 0.00 ATOM 1017 CD2 PHE 179-9.383 2.746 4.126 1.00 0.00 ATOM 1018 2HD PHE 179-9.596 1.875 3.523 1.00 0.00 ATOM 1019 C PHE 179-9.800 4.141-0.226 1.00 0.00 ATOM 1020 O PHE 179-10.456 3.322-0.864 1.00 0.00 ATOM 1021 N ARG+ 180-8.828 4.864-0.754 1.00 0.00 ATOM 1022 H ARG+ 180-8.332 5.488-0.178 1.00 0.00 ATOM 1023 CA ARG+ 180-8.457 4.753-2.155 1.00 0.00 ATOM 1024 HA ARG+ 180-8.888 3.844-2.550 1.00 0.00 ATOM 1025 CB ARG+ 180-8.991 5.948-2.951 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.714 5.820-3.988 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.528 6.848-2.577 1.00 0.00 ATOM 1028 QB ARG+ 180-8.621 6.334-3.283 1.00 0.00 ATOM 1029 CG ARG+ 180-10.497 6.122-2.878 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.751 6.550-1.918 1.00 0.00 ATOM 1031 2HG ARG+ 180-10.966 5.154-2.978 1.00 0.00 ATOM 1032 QG ARG+ 180-10.859 5.852-2.448'1.00 0.00 ATOM 1033 CD ARG+ 180-11.005 7.038-3.980 1.00 0.00 ATOM 1034 1HD ARG+ 180-10.160 7.550-4.419 1.00 0.00 ATOM 1035 2HD ARG+ 180-11.677 7.762-3.546 1.00 0.00 ATOM 1036 QD ARG+ 180-10.919 7.656-3.983 1.00 0.00 ATOM 1037 NE ARG+ 180-11.711 6.299-5.027 1. 00 0.00 ATOM 1038 HE ARG+ 180-11.462 5.354-5.160 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.649 6.837-5.813 1.00 0.00 'ATOM 1040 NH1 ARG+ 180-12.986 8.114-5.662 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.539 8.672-4.964 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13. 684 8.523-6.252 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.112 8.597-5.608 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.236 6.106-6.754 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.977 5.141-6.883 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.930 6.513-7.350 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13. 454 5.827-7.117 1.00 0.00 ATOM 1048 C ARG+ 180-6.940 4.690-2.302 1.00 0.00 ATOM 1049 O ARG+ 180-6. 427 4.310-3.347 1.00 0.00 ATOM 1050 N GLY 181-6.221 5.077-1.258 1.00 0.00 ATOM 1051 H GLY 181-6.672 5.378-0.438 1.00 0.00 ATOM 1052 CA GLY 181-4.773 5.073-1.328 1.00 0.00 ATOM 1053 1HA GLY 181-4.406 6.036-0.998 1.00 0.00 ATOM 1054 2HA GLY 181-4.478 4.926-2.357 1.00 0.00 ATOM 1055 QA GLY 181-4.442 5.481-1.678 1.00 0.00 ATOM 1056 C GLY 181-4.136 3.993-0.488 1.00 0.00 ATOM 1057 O GLY 181-4.726 3.520 0.482 1.00 0.00 ATOM 1058 N VAL 182-2.922 3.611-0.866 1.00 0.00 ATOM 1059 H VAL 182-2.515 4.041-1.644 1.00 0.00 ATOM 1060 CA VAL 182-2.166 2.585-0.159 1.00 0.00 ATOM 1061 HA VAL 182-2.520 2.546 0.864 1.00 0.00 ATOM 1062 CB VAL 182-2.331 1.180-0.797 1.00 0.00 ATOM 1063 HB VAL 182-1.518 1.034-1.495 1.00 0.00 ATOM 1064 QG1 VAL 182-2.212-0.159 0.516 1.00 0.00 ATOM 1065 QG2 VAL 182-3.952 1.019-1.742 1.00 0.00 ATOM 1066 CG1 VAL 182-2.234 0.098 0.265 1.00 0.00

ATOM 1067 1HG1 VAL 182-2.981-0.659 0.076 1.00 0.00 ATOM 1068 2HG1 VAL 182-2.402 0.533 1.240 1.00 0.00 ATOM 1069 3HG1 VAL 182-1.252-0.350 0.234 1.00 0.00 ATOM 1070 CG2 VAL 182-3. 642 1.050-1.562 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.860 0.005-1.726 1.00 0.00 ATOM 1072 2HG2 VAL 182-3.556 1.554-2.512 1.00 0.00 ATOM 1073 3HG2 VAL 182-4.440 1.498-0.987 1.00 0.00 ATOM 1074 QQG VAL 182-3.082 0.430-0.613 1.00 0.00 ATOM 1075 C VAL 182-0.680 2.947-0.153 1.00 0.00 ATOM 1076 O VAL 182-0.110 3.268-1.195 1.00 0.00 ATOM 1077 N GLU 183-0.068 2.893 1.022 1.00 0.00 ATOM 1078 H GLU 183-0.588 2.631 1.814 1.00 0.00 ATOM 1079 CA GLU 183 1.350 3.207 1.186 1.00 0.00 ATOM 1080 HA GLU 183 1.797 3.288 0.204 1.00 0.00 ATOM 1081 CB GLU 183 1.516 4.531 1.935 1.00 0.00 ATOM 1082 1HB GLU 183 1.773 5.304 1.228 1.00 0.00 ATOM 1083 2HB GLU 183 2.319 4.427 2.651 1.00 0.00 ATOM 1084 QB GLU 183 2.046 4.865 1.939 1.00 0.00 ATOM 1085 CG GLU 183 0.269 4.969 2.687 1.00 0.00 ATOM 1086 1HG GLU 183-0.252 4.090 3.036 1.00 0.00 ATOM 1087 2HG GLU 183-0.368 5.521 2.013 1.00 0.00 ATOM 1088 QG GLU 183-0.310 4.805 2.524 1.00 0.00 ATOM 1089 CD GLU 183 0.583 5.846 3.877 1.00 0.00 ATOM 1090 OE1 GLU 183 1.368 6.803 3.715 1.00 0.00 ATOM 1091 OE2 GLU 183 0.039 5.579 4.966 1.00 0.00 ATOM 1092 C GLU 183 2.034 2.089 1.961 1.00 0.00 ATOM 1093 O GLU 183 1.998 2.060 3.183 1.00 0.00 ATOM 1094 N PHE 184 2.616 1.145 1.252 1.00 0.00 ATOM 1095 H PHE 184 2.590 1.195 0.280 1.00 0.00 ATOM 1096 CA PHE 184 3.250 0.005 1.898 1.00 0.00 ATOM 1097 HA PHE 184 3.125 0.130 2.962 1.00 0.00 ATOM 1098 CB PHE 184 2.557-1.296 1.478 1.00 0.00 ATOM 1099 1HB PHE 184 1.674-1.436 2.086 1.00 0.00 ATOM 1100 2HB PHE 184 3.231-2.123 1.654 1.00 0.00 ATOM 1101 QB PHE 184 2.452-1. 780 1.870 1.00 0.00 ATOM 1102 QD PHE 184 2.086-1.352-0.143 1.00 0.00 ATOM 1103 QE PHE 184 1.380-1.489-2.492 1.00 0.00 ATOM 1104 QR PHE 184 1.590-1.450-1.787 1.00 0.00 ATOM 1105 CG PHE 184 2.136-1.347 0.024 1.00 0.00 ATOM 1106 CD1 PHE 184 1.098-0.558-0.453 1.00 0.00 ATOM 1107 1HD PHE 184 0.597 0.122 0.220 1.00 0.00 ATOM 1108 CE1 PHE 184 0.698-0.635-1.773 1.00 0.00 ATOM 1109 1HE PHE 184-0.111-0.014-2.130 1.00 0.00 ATOM 1110 CZ PHE 184 1.336-1.500-2.637 1.00 0.00 ATOM 1111 HZ PHE 184 1.019-1.569-3.666 1.00 0.00 ATOM 1112 CE2 PHE 184 2.371-2.285-2.179 1. 00 0.00 ATOM 1113 2HE PHE 184 2.871-2.964-2.853 1.00 0.00 ATOM 1114 CD2 PHE 184 2.764-2.209-0.857 1.00 0.00 ATOM 1115 2HD PHE 184 3.576-2.826-0.505 1.00 0.00 ATOM 1116 C PHE 184 4.735-0. 098 1.598 1.00 0.00 ATOM 1117 O PHE 184 5.167 0.062 0.460 1.00 0. 00 ATOM 1118 N VAL 185 5.507-0.394 2.632 1.00 0.00 ATOM 1119 H VAL 185 5.093-0.523 3.513 1.00 0.00 ATOM 1120 CA VAL 185 6.943-0.551 2.501 1.00 0.00 ATOM 1121 HA VAL 185 7.238-0.184 1.527 1.00 0.00 ATOM 1122 CB VAL 185 7.700 0.248 3.587 1.00 0.00 ATOM 1123 HB VAL 185 7.885-0.411 4.428 1.00 0.00 ATOM 1124 QG1 VAL 185 9.352 0.856 2.944 1.00 0.00 ATOM 1125 QG2 VAL 185 6.674 1. 699 4.199 1.00 0.00 ATOM 1126 CG1 VAL 185 9.036 0.738 3.066 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.247 0.271 2.117 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.810 0.487 3. 775 1.00 0.00 ATOM 1129 3HG1 VAL 185 8.998 1.810 2.940 1.00 0.00 ATOM 1130 CG2 VAL 185 6.871 1.422 4.080 1.00 0.00 ATOM 1131 1HG2 VAL 185 7.147 2.313 3.538 1.00 0.00 ATOM 1132 2HG2 VAL 185 7.053 1.570 5.135 1. 00 0. 00 ATOM 1133 3HG2 VAL 185 5.823 1.214 3.924 1.00 0.00 ATOM 1134 QQG VAL 185 8.013 1.277 3.571 1.00 0.00 ATOM 1135 C VAL 185 7.299-2.034 2.603 1.00 0.00 ATOM 1136 O VAL 185 7.286-2.614 3.686 1.00 0. 00 ATOM 1137 N CYS 186 7.589-2.655 1.469 1. 00 0. 00 ATOM 1138 H CYS 186 7.567-2.150 0.624 1. 00 0. 00

ATOM 1139 CA CYS 186 7.924-4.073 1.448 1.00 0.00 ATOM 1140 HA CYS 186 7.739-4.464 2.440 1.00 0.00 ATOM 1141 CB CYS 186 7.027-4.825 0.454 1.00 0.00 ATOM 1142 1HB CYS 186 6.029-4.884 0.863 1.00 0.00 ATOM 1143 2HB CYS 186 7.411-5.824 0.325 1.00 0.00 ATOM 1144 QB CYS 186 6.720-5.354 0.594 1.00 0.00 ATOM 1145 SG CYS 186 6.900-4.078-1.202 1.00 0.00 ATOM 1146 C CYS 186 9.399-4.281 1.111 1.00 0.00 ATOM 1147 O CYS 186 9.898-3.738 0.134 1.00 0.00 ATOM 1148 N CYS 187 10.099-5.065 1.923 1.00 0.00 ATOM 1149 H CYS 187 9.654-5.478 2.695 1.00 0.00 ATOM 1150 CA CYS 187 11.524-5.319 1.690 1.00 0.00 ATOM 1151 HA CYS 187 11.922-4.476 1.145 1.00 0.00 ATOM 1152 CB CYS 187 12.287-5.457 3.011 1.00 0.00 ATOM 1153 1HB CYS 187 13.087-6.172 2.880 1.00 0.00 ATOM 1154 2HB CYS 187 11.613-5.818 3.772 1.00 0.00 ATOM 1155 QB CYS 187 12.350-5.995 3.326 1.00 0.00 ATOM 1156 SG CYS 187 13.024-3.906 3.619 1.00 0.00 ATOM 1157 C CYS 187 11.739-6.574 0.865 1.00 0.00 ATOM 1158 O CYS 187 10.991-7.538 0.992 1.00 0.00 ATOM 1159 N PRO 188 12.765-6.561-0.004 1.00 0.00 ATOM 1160 CD PRO 188 13.681-5.428-0.224 1.00 0.00 ATOM 1161 CA PRO 188 13.091-7.699-0.871 1. 00 0.00 ATOM 1162 HA PRO 188 12.272-7.936-1.536 1.00 0.00 ATOM 1163 CB PRO 188 14.292-7.211-1.690 1.00 0.00 ATOM 1164 1HB PRO 188 14.180-7.526-2.717 1.00 0.00 ATOM 1165 2HB PRO 188 15.199-7.630-1.279 1.00 0.00 ATOM 1166 QB PRO 188 14.689-7.578-1.998 1.00 0.00 ATOM 1167 CG PRO 188 14.273-5.725-1.571 1.00 0.00 ATOM 1168 1HG PRO 188 13.659-5.301-2.352 1.00 0.00 ATOM 1169 2HG PRO 188 15.279-5.338-1.633 1.00 0.00 ATOM 1170 QG PRO 188 14.469-5.320-1.993 1.00 0.00 ATOM 1171 1HD PRO 188 13.139-4.494-0.248 1.00 0.00 ATOM 1172 2HD PRO 188 14.452-5.398 0.532 1.00 0.00 ATOM 1173 QD PRO 188 13.795-4.946 0.142 1.00 0.00 ATOM 1174 C PRO 188 13.472-8.949-0.083 1.00 0.00 ATOM 1175 O PRO 188 14.415-8.928 0.714 1.00 0.00 ATOM 1176 N LEU 189 12.739-10.027-0.330 1.00 0.00 ATOM 1177 H LEU 189 12.013-9.966-0.988 1.00 0.00 ATOM 1178 CA LEU 189 12.982-11.305 0.319 1.00 0.00 ATOM 1179 HA LEU 189 13.930-11.244 0.832 1.00 0.00 ATOM 1180 CB LEU 189 11.879-11.620 1.331 1.00 0.00 ATOM 1181 1HB LEU 189 11.060-12.084 0.802 1.00 0.00 ATOM 1182 2HB LEU 189 11.531-10.691 1.757 1.00 0.00 ATOM 1183 QB LEU 189 11.295-11.388 1.279 1.00 0.00 ATOM 1184 CG LEU 189 12.298-12.549 2.471 1.00 0.00 ATOM 1185 HG LEU 189 13.031-13.252 2.100 1.00 0.00 ATOM 1186 QD1 LEU 189 13.088-11.570 3.866 1. 00 0.00 ATOM 1187 QD2 LEU 189 10.822-13.525 3.104 1.00 0.00 ATOM 1188 CD1 LEU 189 12.937-11.757 3.600 1.00 0.00 ATOM 1189 1HD1 LEU 189 12.171-11.218 4.138 1.00 0.00 ATOM 1190 2HD1 LEU 189 13.650-11.058 3.189 1.00 0. 00 ATOM 1191 3HD1 LEU 189 13.442-12.434 4.273 1.00 0.00 ATOM 1192 CD2 LEU 189 11.104-13.338 2.984 1.00 0.00 ATOM 1193 1HD2 LEU 189 10.653-13.879 2.165 1.00 0.00 ATOM 1194 2HD2 LEU 189 10.381-12.659 3.410 1.00 0.00 ATOM 1195 3HD2 LEU 189 11.432-14.036 3.739 1.00 0.00 ATOM 1196 QQD LEU 189 11. 955-12. 547 3.485 1.00 0.00 ATOM 1197 C LEU 189 13.054-12.411-0.729 1.00 0.00 ATOM 1198 OT1 LEU 189 13.616-13.482-0.424 1.00 0.00 ATOM 1199 OT2 LEU 189 12.544-12.192-1.850 1.00 0.00 TER ENDMDL MODEL 18 ATOM 1 N SER 124 9.034 13.125 4.916 1.00 0.00 ATOM 2 CA SER 124 10.292 12.697 4.267 1.00 0.00 ATOM 3 HA SER 124 11.122 12.924 4.919 1.00 0.00 ATOM 4 CB SER 124 10.208 11.187 4.048 1.00 0.00 ATOM 5 1HB SER 124 11.090 10.714 4.458 1.00 0.00 ATOM 6 2HB SER 124 10.145 10.979 2.989 1.00 0.00 ATOM 7 QB SER 124 10.618 10.847 3.724 1.00 0.00 ATOM 8 OG SER 124 9.057 10.655 4.693 1.00 0.00

ATOM 9 HG SER 124 8.888 9.762 4.365 1.00 0.00 ATOM 10 C SER 124 10.474 13.423 2.945 1.00 0.00 ATOM 11 0 SER 124 9.556 14.095 2.474 1.00 0.00 ATOM 12 1HT SER 124 8.455 12.290 5.143 1.00 0.00 ATOM 13 2HT SER 124 8.498 13.743 4.271 1.00 0.00 ATOM 14 3HT SER 124 9.239 13.644 5.790 1.00 0.00 ATOM 15 N ASP 125 11.651 13.279 2.361 1.00 0.00 ATOM 16 H ASP 125 12.336 12.724 2.795 1.00 0.00 ATOM 17 CA ASP 125 11.971 13.908 1.087 1.00 0.00 ATOM 18 HA ASP 125 11.518 14.887 1.064 1.00 0.00 ATOM 19 CB ASP 125 13.490 14.044 0.941 1.00 0.00 ATOM 20 1HB ASP 125 13.777 15.065 1.138 1.00 0.00 ATOM 21 2HB ASP 125 13.772 13.785-0.068 1.00 0.00 ATOM 22 QB ASP 125 13.775 14.425 0.535 1.00 0.00 ATOM 23 CG ASP 125 14.243 13.140 1.898 1.00 0.00 ATOM 24 OD1 ASP 125 15.065 13.657 2.677 1.00 0.00 ATOM 25 OD2 ASP 125 13.985 11.917 1.886 1.00 0.00 ATOM 26 C ASP 125 11.421 13.070-0.055 1.00 0.00 ATOM 27 O ASP 125 10.716 13.569-0.932 1.00 0.00 ATOM 28 N ALA 126 11.755 11.787-0.032 1.00 0. 00 ATOM 29 H ALA 126 12.325 11.459 0.698 1.00 0.00 ATOM 30 CA ALA 126 11.305 10.860-1.057 1.00 0.00 ATOM 31 HA ALA 126 11.286 11.392-1.998 1.00 0.00 ATOM 32 QB ALA 126 12.515 9.429-1.219 1.00 0.00 ATOM 33 CB ALA 126 12.283 9.702-1.189 1.00 0.00 ATOM 34 1HB ALA 126 11.860 8.820-0.730 1.00 0.00 ATOM 35 2HB ALA 126 13.210 9.956-0.694 1.00 0.00 ATOM 36 3HB ALA 126 12.474 9.509-2.233 1.00 0.00 ATOM 37 C ALA 126 9.906 10.338-0.759 1.00 0.00 ATOM 38 O ALA 126 9.446 10.366 0.385 1.00 0.00 ATOM 39 N LEU 127 9.238 9.861-1.802 1.00 0.00 ATOM 40 H LEU 127 9.664 9.869-2.679 1.00 0.00 ATOM 41 CA LEU 127 7.889 9.327-1.680 1.00 0.00 ATOM 42 HA LEU 127 7.598 9.397-0.646 1.00 0.00 ATOM 43 CB LEU 127 6.928 10.161-2.538 1.00 0.00 ATOM 44 1HB LEU 127 6.902 9.724-3.525 1.00 0.00 ATOM 45 2HB LEU 127 7.333 11.159-2.620 1.00 0.00 ATOM 46 QB LEU 127 7.118 10.442-3.072 1.00 0.00 ATOM 47 CG LEU 127 5.482 10.276-2.031 1.00 0.00 ATOM 48 HG LEU 127 5.193 11.318-2.035 1.00 0.00 ATOM 49 QD1 LEU 127 4.313 9.355-3.175 1.00 0.00 ATOM 50 QD2 LEU 127 5.317 9.636-0.268 1.00 0.00 ATOM 51 CD1 LEU 127 4.537 9.531-2.957 1.00 0.00 ATOM 52 1HD1 LEU 127 4.549 9.995-3.932 1.00 0.00 ATOM 53 2HD1 LEU 127 3.536 9.567-2.553 1.00 0.00 ATOM 54 3HD1 LEU 127 4.854 8.502-3.041 1.00 0.00 ATOM 55 CD2 LEU 127 5.349 9.758-0.605 1.00 0.00 ATOM 56 1HD2 LEU 127 4.319 9.837-0.289 1.00 0.00 ATOM 57 2HD2 LEU 127 5.974 10.345 0.051 1.00 0.00 ATOM 58 3HD2 LEU 127 5.658 8.724-0.568 1.00 0.00 ATOM 59 QQD LEU 127 4.815 9.495-1.722 1.00 0.00 ATOM 60 C LEU 127 7.853 7.862-2.114 1.00 0.00 ATOM 61 O LEU 127 6.786 7.280-2.304 1.00 0.00 ATOM 62 N LEU 128 9.028 7.270-2.277 1.00 0.00 ATOM 63 H LEU 128 9.845 7.779-2.115 1.00 0.00 ATOM 64 CA LEU 128 9.124 5.882-2.695 1.00 0.00 ATOM 65 HA LEU 128 8.152 5.433-2.581 1.00 0.00 ATOM 66 CB LEU 128 9.538 5.811-4.170 1.00 0.00 ATOM 67 1HB LEU 128 10.615 5.742-4.215 1.00 0.00 ATOM 68 2HB LEU 128 9.233 6.729-4.651 1.00 0.00 ATOM 69 QB LEU 128 9.924 6.236-4.433 1.00 0.00 ATOM 70 CG LEU 128 8.951 4.636-4.959 1.00 0.00 ATOM 71 HG LEU 128 8.666 3.850-4.274 1.00 0.00 ATOM 72 QUI LEU 128 7.404 5.179-5.879 1.00 0.00 ATOM 73 QD2 LEU 128 10.221 3.947-6.162 1.00 0.00 ATOM 74 CD1 LEU 128 7.701 5.075-5.703 1.00 0.00 ATOM 75 1HD1 LEU 128 7.110 4.207-5.957 1.00 0.00 ATOM 76 2HD1 LEU 128 7.983 5.595-6.607 1.00 0.00 ATOM 77 3HD1 LEU 128 7.119 5.734-5.075 1.00 0.00 ATOM 78 CD2 LEU 128 9.977 4.078-5.931 1.00 0.00 ATOM 79 1HD2 LEU 128 10.423 3.188-5.514 1.00 0.00 ATOM 80 2HD2 LEU 128 10.746 4.817-6.107 1.00 0.00

ATOM 81 3HD2 LEU 128 9.493 3.835-6.865 1.00 0.00 ATOM 82 QQD LEU 128 8.813 4.563-6.021 1.00 0.00 ATOM 83 C LEU 128 10.114 5.133-1.806 1.00 0.00 ATOM 84 O LEU 128 10.235 5.442-0.623 1.00 0.00 ATOM 85 N VAL 129 10.798 4.150-2.388 1.00 0.00 ATOM 86 H VAL 129 10.629 3.967-3.333 1.00 0.00 ATOM 87 CA VAL 129 11.782 3.320-1.676 1.00 0.00 ATOM 88 HA VAL 129 11.244 2.644-1.031 1.00 0.00 ATOM 89 CB VAL 129 12.608 2.478-2.675 1.00 0.00 ATOM 90 HB VAL 129 13.256 3.148-3.222 1.00 0.00 ATOM 91 QG1 VAL 129 13.691 1.228-1.780 1.00 0.00 ATOM 92 QG2 VAL 129 11.486 1.613-3.910 1.00 0.00 ATOM 93 CG1 VAL 129 13.483 1.466-1.952 1.00 0.00 ATOM 94 1HG1 VAL 129 13.720 0.652-2.620 1.00 0.00 ATOM 95 2HG1 VAL 129 12.956 1.084-1.090 1.00 0.00 ATOM 96 3HG1 VAL 129 14.397 1.946-1.631 1.00 0.00 ATOM 97 CG2 VAL 129 11.699 1.779-3.674 1.00 0.00 ATOM 98 1HG2 VAL 129 11.964 2.085-4.675 1.00 0.00 ATOM 99 2HG2 VAL 129 10.672 2.045-3.475 1.00 0.00 ATOM 100 3HG2 VAL 129 11.820 0.709-3.581 1.00 0.00 ATOM 101 QQG VAL 129 12.588 1.420-2.845 1.00 0.00 ATOM 102 C VAL 129 12.749 4.152-0.824 1.00 0.00 ATOM 103 O VAL 129 13.594 4.869-1.358 1.00 0.00 ATOM 104 N PRO 130 12.630 4.061 0.517 1.00 0.00 ATOM 105 CD PRO 130 11.648 3.249 1.235 1.00 0.00 ATOM 106 CA PRO 130 13.486 4.789 1.449 1.00 0.00 ATOM 107 HA PRO 130 13.663 5.792 1.116 1.00 0.00 ATOM 108 CB PRO 130 12.669 4.818 2.755 1.00 0.00 ATOM 109 1HB PRO 130 12.454 5.844 3.016 1.00 0.00 ATOM 110 2HB PRO 130 13.243 4.359 3.546 1.00 0.00 ATOM 111 QB PRO 130 12.849 5.102 3.281 1.00 0.00 ATOM 112 CG PRO 130 11.407 4.052 2.482 1.00 0.00 ATOM 113 1HG PRO 130 10.589 4.742 2.329 1.00 0.00 ATOM 114 2HG PRO 130 11.192 3.396 3.312 1.00 0.00 ATOM 115 QG PRO 130 10.891 4.069 2.821 1.00 0.00 ATOM 116 1HD PRO 130 10.737 3.153 0.664 1.00 0.00 ATOM 117 2HD PRO 130 12.052 2.276 1.478 1.00 0.00 ATOM 118 QD PRO 130 11.395 2.715 1.071 1.00 0.00 ATOM 119 C PRO 130 14.832 4.099 1.671 1.00 0.00 ATOM 120 O PRO 130 15.791 4.336 0.941 1.00 0.00 ATOM 121 N ASP 131 14.888 3.263 2.698 1.00 0.00 ATOM 122 H ASP 131 14.088 3.140 3.238 1.00 0.00 ATOM 123 CA ASP 131 16.112 2.540 3.047 1.00 0.00 ATOM 124 HA ASP 131 16.950 3.177 2.807 1.00 0.00 ATOM 125 CB ASP 131 16.125 2.251 4.555 1.00 0.00 ATOM 126 1HB ASP 131 15.306 1.591 4.796 1.00 0.00 ATOM 127 2HB ASP 131 16.003 3.178 5.093 1.00 0.00 ATOM 128 QB ASP 131 15.655 2.385 4.945 1.00 0.00 ATOM 129 CG ASP 131 17.413 1.. 603 5.019 1.00 0.00 ATOM 130 OD1 ASP 131 18.460 2.277 4.992 1.00 0.00 ATOM 131 OD2 ASP 131 17.367 0.419 5.412 1.00 0.00 ATOM 132 C ASP 131 16.245 1.235 2.248 1.00 0.00 ATOM 133 O ASP 131 16.606 1.249 1.073 1.00 0.00 ATOM 134 N LYS+ 132 15.949 0. 106 2.891 1.00 0.00 ATOM 135 H LYS+ 132 15.674 0.153 3.831 1.00 0.00 ATOM 136 CA LYS+ 132 16.044-1.198 2.236 1.00 0.00 ATOM 137 HA LYS+ 132 16.638-1.074 1.343 1.00 0.00 ATOM 138 CB LYS+ 132 16.731-2.216 3.160 1.00 0.00 ATOM 139 1HB LYS+ 132 16.009-2.579 3.875 1.00 0.00 ATOM 140 2HB LYS+ 132 17.529-1.716 3.692 1.00 0.00 ATOM 141 QB LYS+ 132 16.769-2.147 3.784 1.00 0.00 ATOM 142 CG LYS+ 132 17.327-3.417 2.427 1. 00 0. 00 ATOM 143 1HG LYS+ 132 18.389-3.454 2.628 1.00 0.00 ATOM 144 2HG LYS+ 132 17.166-3.292 1.366 1.00 0.00 ATOM 145 QG LYS+ 132 17.778-3.373 1.997 1. 00 0. 00 ATOM 146 CD LYS+ 132 16.690-4.729 2.874 1.00 0.00 ATOM 147 1HD LYS+ 132 15.616-4.606 2.892 1.00 0.00 ATOM 148 2HD LYS+ 132 17.043-4.967 3.868 1.00 0.00 ATOM 149 QD LYS+ 132 16.330-4.786 3.380 1. 00 0. 00 ATOM 150 CE LYS+ 132 17.047-5.875 1.932 1.00 0.00 ATOM 151 1HE LYS+ 132 18.122-5.978 1.908 1.00 0.00 ATOM 152 2HE LYS+ 132 16.690-5. 631 0.941 1.00 0.00

ATOM 153 QE LYS+ 132 17. 406-5. 804 1. 425 1. 00 0. 00 ATOM 154 NZ LYS+ 132 16. 443-7. 177 2. 357 1. 00 0. 00 ATOM 155 1HZ LYS+ 132 15. 686-7. 467 1. 691 1. 00 0. 00 ATOM 156 2HZ LYS+ 132 16. 035-7. 095 3. 307 1. 00 0. 00 ATOM 157 3HZ LYS+ 132 17. 170-7. 922 2. 370 1. 00 0. 00 ATOM 158 QZ LYS+ 132 16. 297-7. 494 2. 456 1. 00 0. 00 ATOM 159 C LYS+ 132 14. 663-1. 709 1. 845 1. 00 0. 00 ATOM 160 0 LYS+ 132 14. 533-2. 690 1. 111 1. 00 0. 00 ATOM 161 N CYS 133 13. 631-1. 048 2. 337 1. 00 0. 00 ATOM 162 H CYS 133 13. 792-0. 274 2. 915 1. 00 0. 00 ATOM 163 CA CYS 133 12. 265-1. 443 2. 031 1. 00 0. 00 ATOM 164 HA CYS 133 12. 274-2. 490 1. 767 1. 00 0. 00 ATOM 165 CB CYS 133 11. 355-1. 239 3. 246 1. 00 0. 00 ATOM 166 1HB CYS 133 10. 364-0. 984 2. 900 1. 00 0. 00 ATOM 167 2HB CYS 133 11. 739-0. 423 3. 837 1. 00 0. 00 ATOM 168 QB CYS 133 11. 052-0. 703 3. 369 1. 00 0. 00 ATOM 169 SG CYS 133 11. 200-2. 685 4. 346 1. 00 0. 00 ATOM 170 C CYS 133 11. 741-0. 642 0. 850 1. 00 0. 00 ATOM 171 0 CYS 133 12. 192 0. 466 0. 600 1. 00 0. 00 ATOM 172 N LYS+ 134 10. 785-1. 205 0. 131 1. 00 0. 00 ATOM 173 H LYS+ 134 10. 458-2. 093 0. 386 1. 00 0. 00 ATOM 174 CA LYS+ 134 10. 197-0. 543-1. 023 1. 00 0. 00 ATOM 175 HA LYS+ 134 10. 893 0. 207-1. 371 1. 00 0. 00 ATOM 176 CB LYS+ 134 9. 947-1. 561-2. 141 1. 00 0. 00 ATOM 177 HB LYS+ 134 9. 279-2. 324-1. 768 1. 00 0. 00 ATOM 178 2HB LYS+ 134 10. 888-2. 020-2. 406 1. 00 0. 00 ATOM 179 QB LYS+ 134 10. 084-2. 172-2. 087 1. 00 0. 00 ATOM 180 CG LYS+ 134 9. 337-0. 964-3. 399 1. 00 0. 00 ATOM 181 1HG LYS+ 134 9. 709 0. 043-3. 524 1. 00 0. 00 ATOM 182 2HG LYS+ 134 8. 263-0. 942-3. 292 1. 00 0. 00 ATOM 183 QG LYS+ 134 8. 986-0. 449-3. 408 1. 00 0. 00 ATOM 184 CD LYS+ 134 9. 696-1. 779-4. 633 1. 00 0. 00 ATOM 185 1HD LYS+ 134 10. 384-2. 562-4. 348 1. 00 0. 00 ATOM 186 2HD LYS+ 134 10. 169-1. 130-5. 355 1. 00 0. 00 ATOM 187 QD LYS+ 134 10. 277-1. 846-4. 851 1. 00 0. 00 ATOM 188 CE LYS+ 134 8. 464-2. 408-5. 270 1. 00 0. 00 ATOM 189 1HE LYS+ 134 8. 785-3. 157-5. 980 1. 00 0. 00 ATOM 190 2HE LYS+ 134 7. 910-1. 638-5. 787 1. 00 0. 00 ATOM 191 QE LYS+ 134 8. 348-2. 397-5. 883 1. 00 0. 00 ATOM 192 NZ LYS+ 134 7. 577-3. 047-4. 257 1. 00 0. 00 ATOM 193 IHR LYS+ 134 8. 113-3. 261-3. 391 1. 00 0. 00 ATOM 194 2HZ LYS+ 134 7. 180-3. 932-4. 631 1. 00 0. 00 ATOM 195 3HZ LYS+ 134 6. 791-2. 406-4. 013 1. 00 0. 00 ATOM 196 QZ LYS+ 134 7. 362-3. 199-4. 011 1. 00 0. 00 ATOM 197 C LYS+ 134 8. 895 0. 132-0. 624 1. 00 0. 00 ATOM 198 0 LYS+ 134 7. 926-0. 542-0. 290 1. 00 0. 00 ATOM 199 N PHE 135 8. 880 1. 456-0. 651 1. 00 0. 00 ATOM 200 H PHE 135 9. 688 1. 938-0. 923 1. 00 0. 00 ATOM 201 CA PHE 135 7. 693 2. 215-0. 275 1. 00 0. 00 ATOM 202 HA PHE 135 7. 106 1. 605 0. 396 1. 00 0. 00 ATOM 203 CB PHE 135 8. 103 3. 501 0. 447 1. 00 0. 00 ATOM 204 1HB PHE 135 8. 636 4. 137-0. 247 1. 00 0. 00 ATOM 205 2HB PHE 135 8. 758 3. 250 1. 266 1. 00 0. 00 ATOM 206 QB PHE 135 8. 697 3. 694 0. 510 1. 00 0. 00 ATOM 207 QD PHE 135 6. 835 4. 385 1. 076 1. 00 0. 00 ATOM 208 QE PHE 135 4. 984 5. 700 2. 021 1. 00 0. 00 ATOM 209 QR PHE 135 5. 539 5. 306 1. 738 1. 00 0. 00 ATOM 210 CG PHE 135 6. 960 4. 296 1. 012 1. 00 0. 00 ATOM 211 CD1 PHE 135 5. 923 3. 673 1. 684 1. 00 0. 00 ATOM 212 1HD PHE 135 5. 931 2. 599 1. 794 1. 00 0. 00 ATOM 213 CECI PHE 135 4. 884 4. 409 2. 217 1. 00 0. 00 ATOM 214 1HE PHE 135 4. 080 3. 910 2. 741 1. 00 0. 00 ATOM 215 CZ PHE 135 4. 870 5. 781 2. 079 1. 00 0. 00 ATOM 216 HZ PHE 135 4. 055 6. 359 2. 498 1. 00 0. 00 ATOM 217 CE2 PHE 135 5. 897 6. 415 1. 409 1. 00 0. 00 ATOM 218 2HE PHE 135 5. 888 7. 490 1. 300 1. 00 0. 00 ATOM 219 CD2 PHE 135 6. 935 5. 674 0. 881 1. 00 0. 00 ATOM 220 2HD PHE 135 7. 738 6. 171 0. 357 1. 00 0. 00 ATOM 221 C PHE 135 6. 853 2. 542-1. 502 1. 00 0. 00 ATOM 222 0 PHE 135 7. 309 3. 226-2. 418 1. 00 0. 00 ATOM 223 N LEU 136 5. 629 2. 037-1. 513 1. 00 0. 00 ATOM 224 H LEU 136 5. 331 1. 492-0. 751 1. 00 0. 00

ATOM 225 CA LEU 136 4.714 2.259-2.619 1.00 0.00 ATOM 226 HA LEU 136 5.245 2.798-3.388 1.00 0.00 ATOM 227 CB LEU 136 4.213 0.930-3.191 1.00 0.00 ATOM 228 1HB LEU 136 3.532 1.147-4.000 1.00 0.00 ATOM 229 2HB LEU 136 3.663 0.415-2.414 1.00 0.00 ATOM 230 QB LEU 136 3.598 0.781-3.207 1.00 0.00 ATOM 231 CG LEU 136 5.297-0. 009-3.716 1.00 0.00 ATOM 232 HG LEU 136 6.174 0.568-3.961 1.00 0.00 ATOM 233 QD1 LEU 136 5.768-1.258-2.396 1.00 0.00 ATOM 234 QD2 LEU 136 4.711-0.881-5.275 1.00 0.00 ATOM 235 CD1 LEU 136 5.679-1.020-2.650 1.00 0.00 ATOM 236 1HD1 LEU 136 5.246-1.980-2.891 1.00 0.00 ATOM 237 2HD1 LEU 136 5.305-0.688-1.692 1.00 0.00 ATOM 238 3HD1 LEU 136 6.753-1.108-2.605 1.00 0.00 ATOM 239 CD2 LEU 136 4.824-0.715-4.977 1.00 0.00 ATOM 240 1HD2 LEU 136 4.439-1.691-4.721 1.00 0.00 ATOM 241 2HD2 LEU 136 5.651-0.820-5.662 1.00 0.00 ATOM 242 3HD2 LEU 136 4.042-0.132-5.443 1.00 0.00 ATOM 243 QQD LEU 136 5.240-1.070-3.835 1.00 0.00 ATOM 244 C LEU 136 3.524 3.088-2.167 1.00 0.00 ATOM 245 O LEU 136 2.471 2.547-1.838 1.00 0. 00 ATOM 246 N HIS+ 137 3.690 4.398-2.167 1.00 0.00 ATOM 247 H HIS+ 137 4.551 4.774-2.449 1.00 0.00 ATOM 248 CA HIS+ 137 2.619 5.298-1.775 1.00 0.00 ATOM 249 HA HIS+ 137 1.945 4.754-1.124 1.00 0.00 ATOM 250 CB HIS+ 137 3.197 6.511-1.026 1.00 0.00 ATOM 251 1HB HIS+ 137 3.917 6.998-1.666 1.00 0.00 ATOM 252 2HB HIS+ 137 3.700 6.164-0.137 1.00 0.00 ATOM 253 QB HIS+ 137 3.809 6.581-0.901 1.00 0.00 ATOM 254 CG HIS+ 137 2.185 7.544-0.602 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.968 7.888 0.714 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.351 8.329-1.331 1.00 0.00 ATOM 257 1HD HIS+ 137 2.399 7.473 1.504 1.00 0.00 ATOM 258 CE1 HIS+ 137 1.052 8.837 0.773 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.656 9.124-0.454 1.00 0.00 ATOM 260 2HD HIS+ 137 1.249 8.327-2.408 1.00 0.00 ATOM 261 1HE HIS+ 137 0.683 9.299 1.678 1.00 0.00 ATOM 262 2HE HIS+ 137-0.194 9.591-0.671 1.00 0.00 ATOM 263 C HIS+ 137 1.873 5.741-3.026 1.00 0.00 ATOM 264 O HIS+ 137 2.351 6.595-3.773 1.00 0.00 ATOM 265 N GLN 138 0.718 5.143-3.273 1.00 0.00 ATOM 266 H GLN 138 0.388 4.451-2.655 1.00 0.00 ATOM 267 CA GLN 138-0. 062 5.477-4.456 1.00 0.00 ATOM 268 HA GLN 138 0.373 6.360-4.899 1.00 0.00 ATOM 269 CB GLN 138-0.008 4.330-5.474 1.00 0.00 ATOM 270 1HB GLN 138-0.099 4.744-6.468 1.00 0.00 ATOM 271 2HB GLN 138-0.840 3.666-5.293 1.00 0.00 ATOM 272 QB GLN 138-0.469 4.205-5.880 1.00 0.00 ATOM 273 CG GLN 138 1.277 3.512-5.417 1.00 0.00 ATOM 274 1HG GLN 138 1.040 2.480-5.630 1.00 0.00 ATOM 275 2HG GLN 138 1.689 3.586-4.422 1.00 0.00 ATOM 276 QG GLN 138 1.365 3.033-5.026 1.00 0.00 ATOM 277 CD GLN 138 2.320 3.987-6.410 1.00 0. 00 ATOM 278 OE1 GLN 138 2.040 4.124-7.599 1.00 0. 00 ATOM 279 NE2 GLN 138 3.531 4.242-5.927 1.00 0.00 ATOM 280 1HE2 GLN 138 3.686 4.113-4.969 1.00 0.00 ATOM 281 2HE2 GLN 138 4.221 4.552-6.550 1.00 0.00 ATOM 282 QE2 GLN 138 3.954 4.333-5.759 1.00 0.00 ATOM 283 C GLN 138-1.509 5.772-4.094 1.00 0.00 ATOM 284 O GLN 138-2.153 4.998-3.383 1.00 0.00 ATOM 285 N GLU 139-2.018 6.888-4.594 1.00 0.00 ATOM 286 H GLU 139-1.458 7.458-5.158 1.00 0.00 ATOM 287 CA GLU 139-3.392 7.283-4.333 1.00 0.00 ATOM 288 HA GLU 139-3.724 6.761-3.448 1.00 0.00 ATOM 289 CB GLU 139-3.479 8.790-4.087 1.00 0.00 ATOM 290 1HB GLU 139-4.373 8.997-3.517 1.00 0.00 ATOM 291 2HB GLU 139-3.542 9.297-5.038 1.00 0.00 ATOM 292 QB GLU 139-3.957 9.147-4.277 1.00 0.00 ATOM 293 CG GLU 139-2.291 9.349-3.320 1.00 0.00 ATOM 294 1HG GLU 139-2.071 10.340-3.690 1.00 0.00 ATOM 295 2HG GLU 139-1.439 8.706-3.484 1.00 0.00 ATOM 296 QG GLU 139-1.755 9.523-3.587 1.00 0.00

ATOM 297 CD GLU 139-2.552 9.432-1.832 1.00 0.00 ATOM 298 OE1 GLU 139-3.568 8.868-1.373 1.00 0.00 ATOM 299 OE2 GLU 139-1.738 10. 056-1. 124 1.00 0.00 ATOM 300 C GLU 139-4.286 6.886-5.500 1.00 0.00 ATOM 301 O GLU 139-4. 301 7.543-6.542 1.00 0.00 ATOM 302 N ARG+ 140-5.031 5.808-5.323 1.00 0.00 ATOM 303 H ARG+ 140-4.984 5.326-4.468 1.00 0. 00 ATOM 304 CA ARG+ 140-5.930 5.327-6.359 1.00 0.00 ATOM 305 HA ARG+ 140-5.570 5.695-7.308 1.00 0.00 ATOM 306 CB ARG+ 140-5.951 3.791-6.386 1.00 0.00 ATOM 307 1HB ARG+ 140-6.442 3.435-5.489 1.00 0.00 ATOM 308 2HB ARG+ 140-4.935 3.429-6.394 1.00 0.00 ATOM 309 QB ARG+ 140-5.688 3.432-5.941 1.00 0.00 ATOM 310 CG ARG+ 140-6.678 3.199-7.584 1.00 0.00 ATOM 311 1HG ARG+ 140-7.490 3.858-7.859 1.00 0.00 ATOM 312 2HG ARG+ 140-7.076 2.233-7.309 1.00 0.00 ATOM 313 QG ARG+ 140-7.283 3.046-7.584 1.00 0.00 ATOM 314 CD ARG+ 140-5.754 3.028-8.779 1.00 0.00 ATOM 315 1HD ARG+ 140-5.568 1.974-8.926 1.00 0.00 ATOM 316 2HD ARG+ 140-4.823 3.534-8.572 1.00 0.00 ATOM 317 QD ARG+ 140-5.195 2.754-8.749 1.00 0.00 ATOM 318 NE ARG+ 140-6. 339 3.583-9.997 1.00 0.00 ATOM 319 HE ARG+ 140-7.329 3.623-10.051 1.00 0.00 ATOM 320 CZ ARG+ 140-5.624 4.051-11.020 1.00 0.00 ATOM 321 NH1 ARG+ 140-4.296 3.979-10.994 1.00 0.00 ATOM 322 1HH1 ARG+ 140-3.832 3.573-10.207 1.00 0.00 ATOM 323 2HH1 ARG+ 140-3.759 4.332-11.760 1.00 0.00 ATOM 324 QH1 ARG+ 140-3.795 3.953-10.983 1.00 0.00 ATOM 325 NH2 ARG+ 140-6.240 4.580-12.068 1.00 0.00 ATOM 326 1HH2 ARG+ 140-7.254 4.627-12.087 1.00 0.00 ATOM 327 2HH2 ARG+ 140-5.714 4.938-12.839 1.00 0.00 ATOM 328 QH2 ARG+ 140-6.484 4.783-12.463 1.00 0.00 ATOM 329 C ARG+ 140-7.331 5.866-6.119 1.00 0.00 ATOM 330 O ARG+ 140-8.165 5.194-5.516 1.00 0.00 ATOM 331 N MET 141-7.593 7.078-6.596 1.00 0.00 ATOM 332 H MET 141-6.889 7.567-7.072 1.00 0.00 ATOM 333 CA MET 141-8.905 7.702-6.428 1.00 0.00 ATOM 334 HA MET 141-9.220 7.539-5.408 1.00 0.00 ATOM 335 CB MET 141-8.808 9.210-6.686 1.00 0.00 ATOM 336 1HB MET 141-9.008 9.396-7.732 1.00 0.00 ATOM 337 2HB MET 141-7.805 9.539-6.456 1.00 0.00 ATOM 338 QB MET 141-8.406 9.468-7.094 1.00 0.00 ATOM 339 CG MET 141-9. 782 10.037-5.860 1.00 0.00 ATOM 340 1HG MET 141-9.220 10.622-5.147 1.00 0.00 ATOM 341 2HG MET 141-10.441 9.364-5.332 1.00 0.00 ATOM 342 QG MET 141-9.830 9.993-5.239 1.00 0.00 ATOM 343 SD MET 141-10.783 11.151-6.865 1.00 0.00 ATOM 344 QE MET 141-9.388 12.749-7.232 1.00 0.00 ATOM 345 CE MET 141-9.621 12.481-7. 170 1.00 0.00 ATOM 346 1HE MET 141-9.190 12.363-8.154 1.00 0.00 ATOM 347 2HE MET 141-8.838 12.454-6.428 1.00 0.00 ATOM 348 3HE MET 141-10.136 13.429-7.115 1.00 0.00 ATOM 349 C MET 141-9.933 7.065-7.370 1.00 0.00 ATOM 350 O MET 141-10.816 7.741-7.898 1.00 0.00 ATOM 351 N ASP 142-9.806 5.757-7.559 1.00 0.00 ATOM 352 H ASP 142-9.083 5.286-7.096 1.00 0.00 ATOM 353 CA ASP 142-10.692 4. 994-8.418 1.00 0.00 ATOM 354 HA ASP 142-11.343 5.682-8.937 1.00 0.00 ATOM 355 CB ASP 142-9.873 4.200-9.441 1.00 0.00 ATOM 356 1HB ASP 142-10.485 3.403-9.831 1.00 0.00 ATOM 357 2HB ASP 142-9.014 3.775-8.948 1.00 0.00 ATOM 358 QB ASP 142-9.749 3.589-9.389 1.00 0.00 ATOM 359 CG ASP 142-9.385 5.038-10.602 1.00 0.00 ATOM 360 OD1 ASP 142-9.560 6.268-10.568 1.00 0.00 ATOM 361 OD2 ASP 142-8.803 4.457-11.539 1.00 0.00 ATOM 362 C ASP 142-11.521 4. 015-7.602 1.00 0.00 ATOM 363 O ASP 142-12.751 4.008-7.666 1.00 0.00 ATOM 364 N VAL 143-10.826 3.168-6.852 1.00 0.00 ATOM 365 H VAL 143-9. 848 3.218-6.863 1.00 0. 00 ATOM 366 CA VAL 143-11.470 2.143-6.043 1.00 0.00 ATOM 367 HA VAL 143-12.423 1.914-6.497 1.00 0.00 ATOM 368 CB VAL 143-10. 618 0.853-6.026 1. 00 0.00

ATOM 369 HB VAL 143-9.981 0.879-5.151 1.00 0.00 ATOM 370 QG1 VAL 143-11.705-0.668-5.908 1.00 0.00 ATOM 371 QG2 VAL 143-9.515 0.745-7.549 1.00 0.00 ATOM 372 CG1 VAL 143-11.499-0.377-5.929 1.00 0.00 ATOM 373 1HG1 VAL 143-10.978-1.219-6.360 1.00 0.00 ATOM 374 2HG1 VAL 143-12.417-0.206-6.471 1.00 0.00 ATOM 375 3HG1 VAL 143-11.721-0.581-4.893 1.00 0.00 ATOM 376 CG2 VAL 143-9.726 0.766-7.259 1.00 0.00 ATOM 377 1HG2 VAL 143-8.701 0.959-6.976 1.00 0.00 ATOM 378 2HG2 VAL 143-10. 044 1.499-7.986 1.00 0.00 ATOM 379 3HG2 VAL 143-9.801-0.223-7.687 1.00 0.00 ATOM 380 QQG VAL 143-10.610 0.038-6.729 1.00 0.00 ATOM 381 C VAL 143-11. 708 2.629-4.609 1.00 0.00 ATOM 382 O VAL 143-11. 069 3.570-4.151 1.00 0.00 ATOM 383 N CYS 144-12.642 1.983-3.913 1.00 0.00 ATOM 384 H CYS 144-13.122 1.242-4.337 1.00 0.00 ATOM 385 CA CYS 144-12.982 2.350-2.535 1.00 0.00 ATOM 386 HA CYS 144-12.141 2.876-2.098 1.00 0.00 ATOM 387 CB CYS 144-14.215 3.253-2. 519 1.00 0. 00 ATOM 388 1HB CYS 144-14.730 3.120-1.579 1.00 0.00 ATOM 389 2HB CYS 144-14. 872 2.963-3.324 1.00 0.00 ATOM 390 QB CYS 144-14.801 3.042-2.451 1.00 0.00 ATOM 391 SG CYS 144-13.858 5. 026-2.710 1.00 0.00 ATOM 392 C CYS 144-13. 280 1.112-1.710 1.00 0.00 ATOM 393 O CYS 144-14.432 0.683-1.626 1.00 0.00 ATOM 394 N GLU 145-12.258 0.534-1.105 1.00 0.00 ATOM 395 H GLU 145-11.358 0.907-1.203 1.00 0.00 ATOM 396 CA GLU 145-12.447-0.658-0.309 1.00 0.00 ATOM 397 HA GLU 145-13.494-0.912-0.357 1.00 0.00 ATOM 398 CB GLU 145-11.654-1.807-0.903 1.00 0.00 ATOM 399 1HB GLU 145-11. 342-2. 467-0.109 1.00 0.00 ATOM 400 2HB GLU 145-10.776-1.412-1.397 1.00 0.00 ATOM 401 QB GLU 145-11. 059-1. 939-0.753 1.00 0.00 ATOM 402 CG GLU 145-12.471-2.608-1.898 1.00 0.00 ATOM 403 1HG GLU 145-11.946-3.523-2.129 1.00 0.00 ATOM 404 2HG GLU 145-12.598-2.025-2.798 1.00 0.00 ATOM 405 QG GLU 145-12. 272-2. 774-2.463 1.00 0.00 ATOM 406 CD GLU 145-13.837-2.954-1.341 1.00 0.00 ATOM 407 OE1 GLU 145-13.913-3.333-0.151 1.00 0.00 ATOM 408 OE2 GLU 145-14. 831-2. 818-2.071 1.00 0.00 ATOM 409 C GLU 145-12. 073-0. 454 1.143 1.00 0.00 ATOM 410 O GLU 145-11. 642 0.626 1.550 1.00 0.00 ATOM 411 N THR 146-12.265-1.511 1.914 1.00 0.00 ATOM 412 H THR 146-12. 620-2. 331 1.509 1.00 0.00 ATOM 413 CA THR 146-11. 982-1. 504 3.335 1.00 0.00 ATOM 414 HA THR 146-12.364-0.582 3.751 1.00 0.00 ATOM 415 CB THR 146-12. 701-2. 688 3.985 1.00 0.00 ATOM 416 HB THR 146-12.037-3.542 3.986 1.00 0.00 ATOM 417 QG2 THR 146-13.232-2.373 5.756 1.00 0.00 ATOM 418 OG1 THR 146-13.863-3.028 3.239 1.00 0.00 ATOM 419 1HG THR 146-13.968-3.986 3.226 1.00 0.00 ATOM 420 CG2 THR 146-13. 130-2. 435 5.413 1.00 0.00 ATOM 421 1HG2 THR 146-12.450-2.932 6.090 1.00 0.00 ATOM 422 2HG2 THR 146-14.129-2.816 5.565 1.00 0.00 ATOM 423 3HG2 THR 146-13. 119-1.371 5.613 1.00 0.00 ATOM 424 C THR 146-10. 476-1. 575 3.581 1.00 0.00 ATOM 425 O THR 146-9.710-1.933 2.683 1.00 0.00 ATOM 426 N HIS+ 147-10. 064-1.236 4.801 1.00 0.00 ATOM 427 H HIS+ 147-10. 733-0. 960 5.468 1.00 0.00 ATOM 428 CA HIS+ 147-8.651-1.258 5.185 1.00 0.00 ATOM 429 HA HIS+ 147-8.136-0.503 4.610 1. 00 0. 00 ATOM 430 CB HIS+ 147-8.515-0.933 6.676 1.00 0. 00 ATOM 431 1HB HIS+ 147-8.489-1.858 7.235 1.00 0.00 ATOM 432 2HB HIS+ 147-9. 371-0. 355 6.991 1. 00 0. 00 ATOM 433 QB HIS+ 147-8.930-1.106 7.113 1.00 0. 00 ATOM 434 CG HIS+ 147-7.284-0.152 7.021 1.00 0.00 ATOM 435 ND1 HIS+ 147-7.286 1.215 7.198 1.00 0.00 ATOM 436 CD2 HIS+ 147-6.009-0.556 7.237 1.00 0. 00 ATOM 437 1HD HIS+ 147-8.069 1.807 7.103 1.00 0. 00 ATOM 438 CE1 HIS+ 147-6.067 1.619 7.509 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.272 0.564 7.541 1. 00 0. 00 ATOM 440 2HD HIS+ 147-5.635-1.570 7.163 1. 00 0. 00

ATOM 441 1HE HIS+ 147-5.770 2.640 7.703 1.00 0.00 ATOM 442 2HE HIS+ 147-4.292 0.602 7.581 1.00 0.00 ATOM 443 C HIS+ 147-8.020-2.619 4.899 1.00 0.00 ATOM 444 O HIS+ 147-6.842-2.713 4.557 1.00 0.00 ATOM 445 N LEU 148-8.817-3.670 5.049 1.00 0.00 ATOM 446 H LEU 148-9.745-3.526 5.325 1.00 0.00 ATOM 447 CA LEU 148-8.352-5.029 4.821 1.00 0.00 ATOM 448 HA LEU 148-7.427-5.156 5.362 1.00 0.00 ATOM 449 CB LEU 148-9.382-6.025 5.365 1.00 0.00 ATOM 450 1HB LEU 148-10.351-5.762 4.968 1.00 0.00 ATOM 451 2HB LEU 148-9.413-5.926 6.440 1.00 0.00 ATOM 452 QB LEU 148-9.882-5.844 5.704 1.00 0.00 ATOM 453 CG LEU 148-9.111-7.490 5.026 1.00 0.00 ATOM 454 HG LEU 148-8.728-7.552 4.019 1.00 0.00 ATOM 455 QD1 LEU 148-7.815-8.208 6.184 1.00 0.00 ATOM 456 QD2 LEU 148-10.699-8.492 5.111 1.00 0.00 ATOM 457 CD1 LEU 148-8.064-8.070 5. 962 1.00 0.00 ATOM 458 1HD1 LEU 148-7.106-8.087 5.464 1.00 0.00 ATOM 459 2HD1 LEU 148-8.345-9.077 6.236 1.00 0.00 ATOM 460 3HD1 LEU 148-7.996-7.461 6.851 1.00 0.00 ATOM 461 CD2 LEU 148-10.395-8.300 5.095 1.00 0.00 ATOM 462 1HD2 LEU 148-10.834-8.364 4.110 1.00 0.00 ATOM 463 2HD2 LEU 148-11.090-7.820 5.768 1.00 0.00 ATOM 464 3HD2 LEU 148-10.174-9.294 5.455 1.00 0.00 ATOM 465 QQD LEU 148-9.257-8.350 5.648 1.00 0.00 ATOM 466 C LEU 148-8.091-5.297 3.339 1.00 0.00 ATOM 467 O LEU 148-7.128-5.977 2.991 1.00 0.00 ATOM 468 N HIS+ 149-8.950-4.770 2.469 1.00 0.00 ATOM 469 H HIS+ 149-9.703-4.238 2.798 1.00 0.00 ATOM 470 CA HIS+ 149-8.792-4.982 1.032 1.00 0.00 ATOM 471 HA HIS+ 149-8.764-6.050 0.871 1.00 0.00 ATOM 472 CB HIS+ 149-9.965-4.407 0.246 1.00 0.00 ATOM 473 1HB HIS+ 149-9.600-3.654-0.438 1.00 0.00 ATOM 474 2HB HIS+ 149-10.671-3.953 0.927 1.00 0.00 ATOM 475 QB HIS+ 149-10.135-3.803 0.245 1.00 0.00 ATOM 476 CG HIS+ 149-10.686-5.445-0.555 1.00 0.00 ATOM 477 ND1 HIS+ 149-10.041-6.327-1.397 1.00 0.00 ATOM 478 CD2 HIS+ 149-12.002-5.744-0.638 1.00 0.00 ATOM 479 1HD HIS+ 149-9.072-6.363-1.561 1.00 0.00 ATOM 480 CE1 HIS+ 149-10.933-7.121-1.963 1.00 0.00 ATOM 481 NE2 HIS+ 149-12.133-6.788-1.519 1.00 0.00 ATOM 482 2HD HIS+ 149-12.807-5.239-0.118 1.00 0.00 ATOM 483 1HE HIS+ 149-10.717-7.911-2.669 1.00 0.00 ATOM 484 2HE HIS+ 149-12.980-7.085-1.916 1.00 0.00 ATOM 485 C HIS+ 149-7.486-4.398 0.526 1.00 0.00 ATOM 486 0 HIS+ 149-6. 695-5.106-0.090 1.00 0.00 ATOM 487 N TRP 150-7.252-3.115 0.791 1.00 0.00 ATOM 488 H TRP 150-7.921-2.595 1.289 1.00 0.00 ATOM 489 CA TRP 150-6.012-2.469 0.357 1.00 0.00 ATOM 490 HA TRP 150-5.941-2.563-0. 717 1.00 0.00 ATOM 491 CB TRP 150-5. 983-0.990 0.748 1.00 0.00 ATOM 492 1HB TRP 150-5.019-0.580 0.479 1.00 0.00 ATOM 493 2HB TRP 150-6.110-0.909 1.816 1.00 0.00 ATOM 494 QB TRP 150-5. 564-0. 744 1.148 1.00 0.00 ATOM 495 CG TRP 150-7.036-0.143 0.101 1.00 0.00 ATOM 496 CD1 TRP 150-7.504 1.052 0.562 1.00 0.00 ATOM 497 CD2 TRP 150-7.743-0.406-1.117 1.00 0.00 ATOM 498 CE3 TRP 150-7. 722-1.445-2.053 1.00 0.00 ATOM 499 CE2 TRP 150-8.622 0.671-1.324 1.00 0.00 ATOM 500 NE1 TRP 150-8.458 1.545-0.288 1.00 0.00 ATOM 501 HD TRP 150-7.165 1.529 1.470 1.00 0.00 ATOM 502 3HE TRP 150-7.065-2.291-1.935 1.00 0.00 ATOM 503 CZ3 TRP 150-8.564-1.374-3.141 1.00 0.00 ATOM 504 CZ2 TRP 150-9.465 0.741-2.422 1.00 0.00 ATOM 505 1HE TRP 150-8. 946 2.389-0.172 1.00 0.00 ATOM 506 3HZ TRP 150-8.566-2.169-3.872 1.00 0.00 ATOM 507 CH2 TRP 150-9. 423-0.288-3.316 1.00 0.00 ATOM 508 2HZ TRP 150-10. 138 1.574-2.575 1.00 0.00 ATOM 509 HH TRP 150-10.066-0.276-4.183 1.00 0. 00 ATOM 510 C TRP 150-4.818-3.168 0.968 1.00 0.00 ATOM 511 O TRP 150-3.781-3.283 0.333 1.00 0. 00 ATOM 512 N HIS+ 151-4.978-3.652 2.194 1. oo 0. 00

ATOM 513 H HIS+ 151-5.841-3.539 2.646 1.00 0.00 ATOM 514 CA HIS+ 151-3.908-4.367 2.870 1.00 0.00 ATOM 515 HA HIS+ 151-3.053-3.712 2.932 1.00 0.00 ATOM 516 CB HIS+ 151-4.349-4.774 4.286 1.00 0.00 ATOM 517 1HB HIS+ 151-5.218-5.414 4.208 1.00 0.00 ATOM 518 2HB HIS+ 151-4. 617-3.885 4.836 1.00 0. 00 ATOM 519 QB HIS+ 151-4.917-4.649 4.522 1.00 0.00 ATOM 520 CG HIS+ 151-3.307-5.508 5.083 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.944-5.146 6.363 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.564-6.602 4.783 1.00 0.00 ATOM 523 1HD HIS+ 151-3.304-4.385 6.869 1.00 0.00 ATOM 524 CE1 HIS+ 151-2. 025-5.984 6.812 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.778-6.876 5.873 1.00 0.00 ATOM 526 2HD HIS+ 151-2.580-7.145 3.845 1.00 0.00 ATOM 527 1HE HIS+ 151-1.548-5.940 7.781 1.00 0.00 ATOM 528 2HE HIS+ 151-1.214-7.669 5.984 1.00 0.00 ATOM 529 C HIS+ 151-3.536-5.596 2.052 1.00 0.00 ATOM 530 O HIS+ 151-2. 359-5.867 1.820 1.00 0.00 ATOM 531 N THR 152-4.551-6.327 1.612 1.00 0.00 ATOM 532 H THR 152-5.466-6.052 1.828 1.00 0.00 ATOM 533 CA THR 152-4.341-7.521 0.812 1.00 0.00 ATOM 534 HA THR 152-3.618-8.137 1.325 1.00 0.00 ATOM 535 CB THR 152-5.648-8.304 0.668 1.00 0.00 ATOM 536 HB THR 152-6.262-7.828-0.083 1.00 0.00 ATOM 537 QG2 THR 152-5.395-10.088 0.156 1.00 0.00 ATOM 538 OG1 THR 152-6.361-8.316 1.895 1.00 0.00 ATOM 539 1HG THR 152-6.616-7.417 2.132 1.00 0.00 ATOM 540 CG2 THR 152-5.444-9.745 0.255 1.00 0.00 ATOM 541 1HG2 THR 152-4.796-10.236 0.966 1.00 0.00 ATOM 542 2HG2 THR 152-4.992-9.778-0.727 1.00 0.00 ATOM 543 3HG2 THR 152-6.398-10.250 0.228 1.00 0.00 ATOM 544 C THR 152-3.771-7.164-0.553 1.00 0.00 ATOM 545 O THR 152-2.775-7.741-0.957 1.00 0.00 ATOM 546 N VAL 153-4.384-6.199-1.244 1.00 0.00 ATOM 547 H VAL 153-5. 169-5.751-0.855 1.00 0.00 ATOM 548 CA VAL 153-3.896-5.781-2.559 1.00 0.00 ATOM 549 HA VAL 153-3.949-6.634-3.217 1.00 0.00 ATOM 550 CB VAL 153-4.759-4.644-3.155 1.00 0.00 ATOM 551 HB VAL 153-4.651-3.771-2.529 1.00 0.00 ATOM 552 QG1 VAL 153-4.182-4.201-4.890 1.00 0.00 ATOM 553 QG2 VAL 153-6.574-5.135-3.177 1.00 0.00 ATOM 554 CG1 VAL 153-4.293-4.286-4.558 1.00 0.00 ATOM 555 1HG1 VAL 153-3.257-4.571-4.678 1.00 0.00 ATOM 556 2HG1 VAL 153-4.394-3.222-4.710 1.00 0.00 ATOM 557 3HG1 VAL 153-4.897-4.812-5.282 1.00 0.00 ATOM 558 CG2 VAL 153-6.227-5.041-3.173 1.00 0.00 ATOM 559 1HG2 VAL 153-6.768-4.389-3.843 1.00 0.00 ATOM 560 2HG2 VAL 153-6. 636-4.954-2.177 1.00 0.00 ATOM 561 3HG2 VAL 153-6.319-6.062-3.513 1.00 0.00 ATOM 562 QQG VAL 153-5.378-4.668-4.034 1.00 0.00 ATOM 563 C VAL 153-2.446-5.330-2.467 1.00 0.00 ATOM 564 O VAL 153-1.602-5.735-3.266 1.00 0.00 ATOM 565 N ALA 154-2.166-4.508-1.471 1.00 0.00 ATOM 566 H ALA 154-2.891-4.236-0.860 1.00 0.00 ATOM 567 CA ALA 154-0.821-4.011-1.241 1.00 0.00 ATOM 568 HA ALA 154-0.496-3.479-2.124 1.00 0.00 ATOM 569 QB ALA 154-0.824-2.819 0.208 1.00 0.00 ATOM 570 CB ALA 154-0. 824-3.048-0.070 1.00 0.00 ATOM 571 1HB ALA 154-1.839-2.744 0.145 1.00 0.00 ATOM 572 2HB ALA 154-0.232-2.180-0.318 1.00 0.00 ATOM 573 3HB ALA 154-0. 403-3.535 0.797 1.00 0.00 ATOM 574 C ALA 154 0. 140-5.158-0.969 1. 00 0.00 ATOM 575 O ALA 154 1.191-5.272-1.607 1.00 0.00 ATOM 576 N LYS+ 155-0. 230-6.008-0.016 1. 00 0. 00 ATOM 577 H LYS+ 155-1.081-5.859 0.451 1.00 0.00 ATOM 578 CA LYS+ 155 0.590-7.153 0.352 1.00 0.00 ATOM 579 HA LYS+ 155 1.559-6.781 0.667 1.00 0.00 ATOM 580 CB LYS+ 155-0.053-7.934 1.504 1.00 0.00 ATOM 581 1HB LYS+ 155-0.960-8.399 1.144 1.00 0.00 ATOM 582 2HB LYS+ 155-0. 307-7.241 2.295 1. 00 0. 00 ATOM 583 QB LYS+ 155-0.633-7.820 1.720 1. 00 0. 00 ATOM 584 CG LYS+ 155 0.842-9.020 2.088 1.00 0.00

ATOM 585 1HG LYS+ 155 1.478-8.581 2.843 1.00 0.00 ATOM 586 2HG LYS+ 155 1.450-9.434 1.297 1.00 0.00 ATOM 587 QG LYS+ 155 1.464-9.007 2.070 1.00 0.00 ATOM 588 CD LYS+ 155 0.027-10.141 2.716 1.00 0.00 ATOM 589 1HD LYS+ 155-1.021-9.869 2.693 1.00 0.00 ATOM 590 2HD LYS+ 155 0.343-10.272 3. 742 1.00 0.00 ATOM 591 QD LYS+ 155-0. 339-10.070 3.218 1.00 0.00 ATOM 592 CE LYS+ 155 0.215-11.457 1.968 1.00 0.00 ATOM 593 1HE LYS+ 155-0.060-11.309 0.933 1.00 0.00 ATOM 594 2HE LYS+ 155-0.435-12.202 2.407 1.00 0.00 ATOM 595 QE LYS+ 155-0.247-11.755 1.670 1.00 0.00 ATOM 596 NZ LYS+ 155 1.627-11.943 2.034 1.00 0.00 ATOM 597 1HZ LYS+ 155 2.065-11.658 2.933 1.00 0.00 ATOM 598 2HZ LYS+ 155 2. 187-11.538 1.245 1.00 0.00 ATOM 599 3HZ LYS+ 155 1.655-12.982 1.960 1.00 0.00 ATOM 600 QZ LYS+ 155 1.969-12.059 2.046 1.00 0.00 ATOM 601 C LYS+ 155 0.790-8.063-0.843 1.00 0.00 ATOM 602 O LYS+ 155 1.907-8.491-1.099 1.00 0.00 ATOM 603 N GLU 156-0.289-8.351-1.565 1.00 0.00 ATOM 604 H GLU 156-1.163-7.972-1.299 1.00 0.00 ATOM 605 CA GLU 156-0. 224-9.210-2.741 1.00 0.00 ATOM 606 HA GLU 156 0.108-10.184-2.420 1.00 0.00 ATOM 607 CB GLU 156-1.600-9.346-3.393 1.00 0.00 ATOM 608 1HB GLU 156-1.471-9.654-4.421 1.00 0.00 ATOM 609 2HB GLU 156-2.093-8.385-3.376 1.00 0.00 ATOM 610 QB GLU 156-1.782-9.019-3.898 1.00 0.00 ATOM 611 CG GLU 156-2.507-10.352-2.705 1.00 0.00 ATOM 612 1HG GLU 156-2.362-10.280-1.639 1.00 0.00 ATOM 613 2HG GLU 156-2.245-11.344-3.040 1.00 0.00 ATOM 614 QG GLU 156-2.303-10.812-2.339 1.00 0.00 ATOM 615 CD GLU 156-3.970-10.112-3.010 1.00 0.00 ATOM 616 OE1 GLU 156-4.776-11.040-2.802 1.00 0.00 ATOM 617 OE2 GLU 156-4.310-8.994-3.451 1.00 0.00 ATOM 618 C GLU 156 0.772-8.665-3.757 1.00 0.00 ATOM 619 O GLU 156 1.654-9.388-4.199 1.00 0.00 ATOM 620 N THR 157 0.633-7.388-4.112 1.00 0.00 ATOM 621 H THR 157-0.095-6.860-3.714 1.00 0.00 ATOM 622 CA THR 157 1.534-6.751-5.076 1.00 0.00 ATOM 623 HA THR 157 1.380-7.229-6.032 1.00 0. 00 ATOM 624 CB THR 157 1.200-5.259-5.210 1.00 0.00 ATOM 625 HB THR 157 1.477-4.754-4.294 1.00 0.00 ATOM 626 QG2 THR 157 2.100-4.416-6.623 1.00 0.00 ATOM 627 OG1 THR-157-0. 188-5.065-5.422 1.00 0.00 ATOM 628 1HG THR 157-0.686-5.420-4.673 1.00 0.00 ATOM 629 CG2 THR 157 1.927-4.577-6.350 1.00 0.00 ATOM 630 1HG2 THR 157 1.239-4.413-7.168 1.00 0. 00 ATOM 631 2HG2 THR 157 2.740-5.206-6.686 1.00 0.00 ATOM 632 3HG2 THR 157 2.320-3.629-6.015 1.00 0.00 ATOM 633 C THR 157 3.005-6.927-4.676 1.00 0.00 ATOM 634 O THR 157 3.877-7.110-5.525 1.00 0.00 ATOM 635 N CYS 158 3.283-6.866-3.383 1.00 0.00 ATOM 636 H CYS 158 2.556-6.708-2.739 1.00 0.00 ATOM 637 CA CYS 158 4.651-7.021-2.903 1.00 0. 00 ATOM 638 HA CYS 158 5.305-6.571-3.635 1.00 0.00 ATOM 639 CB CYS 158 4.821-6.285-1.579 1.00 0.00 ATOM 640 1HB CYS 158 5.691-6.657-1.071 1.00 0.00 ATOM 641 2HB CYS 158 3.953-6.469-0.967 1.00 0.00 ATOM 642 QB CYS 158 4.822-6.563-1.019 1.00 0.00 ATOM 643 SG CYS 158 5.001-4.475-1.773 1.00 0.00 ATOM 644 C CYS 158 5.031-8.500-2.766 1.00 0.00 ATOM 645 O CYS 158 6.128-8.895-3.160 1.00 0.00 ATOM 646 N SER 159 4.125-9.303-2. 205 1.00 0.00 ATOM 647 H SER 159 3. 274-8.919-1.908 1.00 0.00 ATOM 648 CA SER 159 4.355-10.738-2.009 1.00 0.00 ATOM 649 HA SER 159 5.291-10.851-1.481 1.00 0.00 ATOM 650 CB SER 159 3.234-11.353-1.163 1.00 0.00 ATOM 651 1HB SER 159 3.489-12.374-0.922 1.00 0.00 ATOM 652 2HB SER 159 2.316-11.340-1.731 1.00 0.00 ATOM 653 QB SER 159 2.903-11.857-1.32'6 1.00 0.00 ATOM 654 OG SER 159 3.031-10.630 0.046 1.00 0.00 ATOM 655 HG SER 159 2.835-9.707-0. 170 1.00 0.00 ATOM 656 C SER 159 4.452-11.491-3.339 1.00 0.00

ATOM 657 O SER 159 5.115-12.521-3.414 1.00 0.00 ATOM 658 N GLU 160 3.788-10.974-4.377 1.00 0.00 ATOM 659 H GLU 160 3.269-10.150-4.252 1.00 0.00 ATOM 660 CA GLU 160 3.810-11.601-5.700 1.00 0.00 ATOM 661 HA GLU 160 3.472-12.621-5.595 1.00 0.00 ATOM 662 CB GLU 160 2.881-10.851-6.664 1.00 0.00 ATOM 663 1HB GLU 160 3.447-10.072-7.156 1.00 0.00 ATOM 664 2HB GLU 160 2.083-10.396-6.098 1.00 0.00 ATOM 665 QB GLU 160 2.765-10.234-6.627 1.00 0.00 ATOM 666 CG GLU 160 2.259-11.731-7.737 1.00 0.00 ATOM 667 1HG GLU 160 1.561-12.410-7.271 1.00 0.00 ATOM 668 2HG GLU 160 3.042-12.296-8.222 1.00 0.00 ATOM 669 QG GLU 160 2.302-12.353-7.746 1.00 0.00 ATOM 670 CD GLU 160 1.521-10.927-8.787 1.00 0.00 ATOM 671 OE1 GLU 160 0.471-11.401-9.266 1.00 0.00 ATOM 672 OE2 GLU 160 1.993-9.823-9.131 1.00 0.00 ATOM 673 C GLU 160 5.234-11.599-6.238 1.00 0.00 ATOM 674 O GLU 160 5.655-12.509-6. 953 1.00 0.00 ATOM 675 N LYS+ 161 5.980-10.577-5.846 1.00 0.00 ATOM 676 H LYS+ 161 5.587-9. 907-5.254 1.00 0.00 ATOM 677 CA LYS+ 161 7.366-10.446-6.233 1.00 0.00 ATOM 678 HA LYS+ 161 7.515-11.004-7.147 1.00 0.00 ATOM 679 CB LYS+ 161 7.735-8.973-6.458 1.00 0.00 ATOM 680 1HB LYS+ 161 8.106-8.564-5.530 1.00 0.00 ATOM 681 2HB LYS+ 161 6.847-8.433-6.748 1.00 0.00 ATOM 682 QB LYS+ 161 7.477-8.498-6.139 1.00 0.00 ATOM 683 CG LYS+ 161 8.799-8.764-7.532 1.00 0.00 ATOM 684 1HG LYS+ 161 8.358-8.220-8.357 1.00 0.00 ATOM 685 2HG LYS+ 161 9.138-9.729-7.880 1.00 0.00 ATOM 686 QG LYS+ 161 8.748-8.974-8.118 1.00 0.00 ATOM 687 CD LYS+ 161 9.997-7.981-7.008 1.00 0.00 ATOM 688 1HD LYS+ 161 10.141-8.216-5.964 1.00 0.00 ATOM 689 2HD LYS+ 161 9.796-6.924-7.116 1.00 0.00 ATOM 690 QD LYS+ 161 9.969-7.570-6.540 1.00 0.00 ATOM 691 CE LYS+ 161 11.266-8.323-7.778 1.00 0.00 ATOM 692 1HE LYS+ 161 11.683-7.411-8.181 1.00 0.00 ATOM 693 2HE LYS+ 161 11.010-8.988-8.590 1.00 0.00 ATOM 694 QE LYS+ 161 11.347-8.199-8.385 1.00 0.00 ATOM 695 NZ LYS+ 161 12.289-8.986-6.917 1.00 0.00 ATOM 696 1HZ LYS+ 161 12.569-8.358-6.137 1.00 0.00 ATOM 697 2HZ LYS+ 161 13.134-9.218-7.477 1.00 0.00 ATOM 698 3HZ LYS+ 161 11.905-9.876-6.510 1.00 0.00 ATOM 699 QZ LYS+ 161 12.536-9.150-6.708 1.00 0.00 ATOM 700 C LYS+ 161 8.224-11.049-5.130 1.00 0.00 ATOM 701 O LYS+ 161 7.910-12.104-4.591 1.00 0.00 ATOM 702 N SER 162 9.300-10.376-4.786 1.00 0.00 ATOM 703 H SER 162 9.503-9.537-5.234 1.00 0.00 ATOM 704 CA SER 162 10.172-10.856-3.739 1.00 0.00 ATOM 705 HA SER 162 9.761-11.783-3.370 1.00 0.00 ATOM 706 CB SER 162 11.574-11.121-4.294 1.00 0.00 ATOM 707 1HB SER 162 11.961-12.035-3.863 1.00 0.00 ATOM 708 2HB SER 162 12.224-10.300-4.029 1.00 0.00 ATOM 709 QB SER 162 12.093-11.167-3.946 1.00 0.00 ATOM 710 OG SER 162 11.546-11.254-5.713 1.00 0.00 ATOM 711 HG SER 162 11.335-12.171-5.939 1.00 0.00 ATOM 712 C SER 162 10.233-9.857-2.590 1.00 0.00 ATOM 713 O SER 162 11.314-9.470-2.163 1.00 0.00 ATOM 714 N THR 163 9.071-9.429-2.091 1.00 0.00 ATOM 715 H THR 163 8.224-9.759-2.469 1.00 0.00 ATOM 716 CA THR 163 9.035-8.481-0.982 1.00 0.00 ATOM 717 HA THR 163 9.948-8.606-0.416 1.00 0.00 ATOM 718 CB THR 163 8.959-7.034-1.475 1.00 0.00 ATOM 719 HB THR 163 8.860-6.391-0.604 1.00 0.00 ATOM 720 QG2 THR 163 10.467-6.467-2.432 1.00 0.00 ATOM 721 OG1 THR 163 7.835-6.841-2.316 1.00 0.00 ATOM 722 1HG THR 163 7.512-7.700-2.625 1.00 0.00 ATOM 723 CG2 THR 163 10.176-6.575-2.249 1.00 0.00 ATOM 724 1HG2 THR 163 10.660-5.769-1.716 1.00 0.00 ATOM 725 2HG2 THR 163 9.874-6.231-3.226 1.00 0.00 ATOM 726 3HG2 THR 163 10.867-7.401-2.354 1.00 0.00 ATOM 727 C THR 163 7.856-8.767-0.058 1.00 0.00 ATOM 728 O THR 163 6.891-9.426-0.440 1.00 0.00

ATOM 729 N ASN 164 7.945-8.266 1.162 1.00 0.00 ATOM 730 H ASN 164 8.748-7.753 1.406 1.00 0.00 ATOM 731 CA ASN 164 6.894-8.464 2.160 1.00 0.00 ATOM 732 HA ASN 164 6.047-8.929 1.666 1.00 0.00 ATOM 733 CB ASN 164 7.400-9.384 3.277 1.00 0.00 ATOM 734 1HB ASN 164 7.172-10.408 3.025 1.00 0.00 ATOM 735 2HB ASN 164 6.908-9.126 4.203 1.00 0.00 ATOM 736 QB ASN 164 7.040-9.767 3.614 1.00 0.00 ATOM 737 CG ASN 164 8.899-9.264 3.479 1.00 0.00 ATOM 738 OD1 ASN 164 9.600-10.259 3.616 1.00 0.00 ATOM 739 ND2 ASN 164 9.394-8.033 3.510 1.00 0.00 ATOM 740 1HD2 ASN 164 8.767-7.283 3.425 1.00 0.00 ATOM 741 2HD2 ASN 164 10.361-7.925 3.555 1.00 0.00 ATOM 742 QD2 ASN 164 9.564-7.604 3.490 1.00 0.00 ATOM 743 C ASN 164 6.459-7.133 2.762 1.00 0.00 ATOM 744 O ASN 164 7.300-6.312 3.128 1.00 0.00 ATOM 745 N LEU 165 5.152-6.920 2.864 1.00 0.00 ATOM 746 H LEU 165 4.533-7.610 2.558 1.00 0.00 ATOM 747 CA LEU 165 4.617-5.680 3.427 1.00 0.00 ATOM 748 HA LEU 165 5.077-4.846 2.915 1.00 0.00 ATOM 749 CB LEU 165 3.104-5.602 3.242 1.00 0.00 ATOM 750 1HB LEU 165 2.649-5.473 4.214 1.00 0.00 ATOM 751 2HB LEU 165 2.760-6.534 2.820 1.00 0.00 ATOM 752 QB LEU 165 2.705-6.003 3.517 1.00 0.00 ATOM 753 CG LEU 165 2.631-4.467 2.356 1.00 0.00 ATOM 754 HG LEU 165 3.126-3.553 2.651 1.00 0.00 ATOM 755 QD1 LEU 165 3.076-4.821 0.574 1.00 0.00 ATOM 756 QD2 LEU 165 0.779-4.217 2.548 1.00 0.00 ATOM 757 CD1 LEU 165 2.991-4.754 0.918 1.00 0.00 ATOM 758 1HD1 LEU 165 3.745-4.055 0.588 1.00 0.00 ATOM 759 2HD1 LEU 165 2.110-4.649 0.299 1.00 0.00 ATOM 760 3HD1 LEU 165 3.371-5.760 0.835 1.00 0.00 ATOM 761 CD2 LEU 165 1.134-4.266 2.512 1.00 0.00 ATOM 762 1HD2 LEU 165 0.872-4.299 3.559 1.00 0.00 ATOM 763 2HD2 LEU 165 0.608-5.047 1.983 1.00 0.00 ATOM 764 3HD2 LEU 165 0.856-3.306 2.101 1.00 0.00 ATOM 765 QQD LEU 165 1.927-4.519 1.561 1.00 0.00 ATOM 766 C LEU 165 4.930-5.564 4.903 1.00 0.00 ATOM 767 O LEU 165 4.571-6.434 5.693 1.00 0.00 ATOM 768 N HIS+ 166 5.581-4.477 5.263 1.00 0.00 ATOM 769 H HIS+ 166 5.827-3.815 4.582 1.00 0.00 ATOM 770 CA HIS+ 166 5.929-4.225 6.644 1.00 0.00 ATOM 771 HA HIS+ 166 5.642-5.090 7.223 1.00 0.00 ATOM 772 CB HIS+ 166 7.440-4.005 6.778 1.00 0.00 ATOM 773 1HB HIS+ 166 7.721-3.136 6.198 1.00 0.00 ATOM 774 2HB HIS+ 166 7.959-4.869 6.394 1.00 0.00 ATOM 775 QB HIS+ 166 7.840-4.002 6.296 1.00 0.00 ATOM 776 CG HIS+ 166 7.895-3.783 8.185.1.00 0. 00 ATOM 777 ND1 HIS+ 166 7.891-4.765 9. 151 1.00 0. 00 ATOM 778 CD2 HIS+ 166 8.359-2.668 8.786 1.00 0.00 ATOM 779 1HD HIS+ 166 7.599-5.693 9.. 024 1.00 0. 00 ATOM 780 CE1 HIS+ 166 8.332-4.257 10.289 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.623-2.981 10.093 1.00 0.00 ATOM 782 2HD HIS+ 166 8.479-1.694 8.321 1.00 0.00 ATOM 783 1HE HIS+ 166 8.438-4.794 11.221 1.00 0.00 ATOM 784 2HE HIS+ 166 8.752-2.322 10.807 1.00 0.00 ATOM 785 C HIS+ 166 5.158-3.010 7.156 1.00 0.00 ATOM 786 O HIS+ 166 4.511-3.070 8.202 1.00 0.00 ATOM 787 N ASP 167 5.227-1.912 6.406 1.00 0.00 ATOM 788 H ASP 167 5.756-1.931 5.579 1.00 0.00 ATOM 789 CA ASP 167 4.537-0.679 6.789 1.00 0.00 ATOM 790 HA ASP 167 4.032-0.865 7.725 1.00 0.00 ATOM 791 CB ASP 167 5.527 0.477 6.984 1.00 0.00 ATOM 792 1HB ASP 167 5.115 1.170 7.703 1.00 0.00 ATOM 793 2HB ASP 167 5.661 0.986 6.042 1. 00 0. 00 ATOM 794 QB ASP 167 5.388 1.078 6.873 1.00 0.00 ATOM 795 CG ASP 167 6.886 0.031 7.478 1.00 0.00 ATOM 796 OD1 ASP 167 7.127 0.110 8.700 1.00 0.00 ATOM 797 OD2 ASP 167 7.713-0.399 6.644 1. 00 0. 00 ATOM 798 C ASP 167 3.498-0.276 5.746 1.00 0.00 ATOM 799 O ASP 167 3.794 0. 459 4.807 1.00 0.00 ATOM 800 N TYR 168 2.283-0.764 5.917 1.00 0.00

ATOM 801 H TYR 168 2.112-1.344 6.688 1.00 0.00 ATOM 802 CA TYR 168 1.180-0.459 5.004 1.00 0.00 ATOM 803 HA TYR 168 1.596-0.225 4.025 1.00 0.00 ATOM 804 CB TYR 168 0.256-1.675 4.884 1.00 0.00 ATOM 805 1HB TYR 168 0.640-2.338 4.124 1.00 0.00 ATOM 806 2HB TYR 168-0.731-1.340 4.598 1.00 0.00 ATOM 807 QB TYR 168-0.045-1.839 4.361 1.00 0.00 ATOM 808 QD TYR 168 0. 116-2. 548 6.327 1.00 0.00 ATOM 809 QE TYR 168-0.078-3.795 8.436 1.00 0.00 ATOM 810 QR TYR 168 0.019-3.171 7.382 1.00 0.00 ATOM 811 CG TYR 168 0.128-2.458 6.175 1.00 0.00 ATOM 812 CD1 TYR 168 0.979-3.522 6.457 1.00 0.00 ATOM 813 1HD TYR 168 1.733-3.799 5.736 1.00 0.00 ATOM 814 CE1 TYR 168 0.872-4.225 7.641 1.00 0.00 ATOM 815 1HE TYR 168 1.542-5.048 7.844 1.00 0.00 ATOM 816 CZ TYR 168-0.090-3.869 8.560 1.00 0.00 ATOM 817 CE2 TYR 168-0.945-2.820 8.305 1.00 0.00 ATOM 818 2HE TYR 168-1.698-2.542 9.027 1.00 0.00 ATOM 819 CD2 TYR 168-0.832-2.121 7.120 1.00 0.00 ATOM 820 2HD TYR 168-1.501-1.297 6.918 1.00 0.00 ATOM 821 OH TYR 168-0.202-4.566 9.738 1.00 0.00 ATOM 822 HH TYR 168 0.490-4.282 10.343 1.00 0.00 ATOM 823 C TYR 168 0.381 0.744 5.493 1.00 0.00 ATOM 824 O TYR 168 0.256 0.976 6.694 1.00 0.00 ATOM 825 N GLY 169-0.177 1.486 4.553 1.00 0.00 ATOM 826 H GLY 169-0.055 1.240 3.612 1.00 0.00 ATOM 827 CA GLY 169-0.976 2.643 4.884 1.00 0.00 ATOM 828 1HA GLY 169-0.353 3.527 4.859 1.00 0.00 ATOM 829 2HA GLY 169-1.382 2.521 5.878 1.00 0.00 ATOM 830 QA GLY 169-0.867 3.024 5.369 1.00 0.00 ATOM 831 C GLY 169-2.104 2.807 3.899 1.00 0.00 ATOM 832 O GLY 169-2.026 2.295 2.783 1.00 0.00 ATOM 833 N MET 170-3.156 3.500 4.295 1.00 0.00 ATOM 834 H MET 170-3.168 3.882 5.197 1.00 0.00 ATOM 835 CA MET 170-4.297 3.709 3.416 1.00 0.00 ATOM 836 HA MET 170-3.968 3.523 2.397 1.00 0.00 ATOM 837 CB MET 170-5.436 2.743 3.766 1.00 0.00 ATOM 838 1HB MET 170-6.351 3.112 3.323 1.00 0.00 ATOM 839 2HB MET 170-5.554 2.719 4.839 1.00 0.00 ATOM 840 QB MET 170-5.952 2.916 4.081 1.00 0.00 ATOM 841 CG MET 170-5.210 1.319 3.277 1.00 0.00 ATOM 842 1HG MET 170-4.604 1.353 2.383 1.00 0.00 ATOM 843 2HG MET 170-6.169 0.877 3.044 1.00 0.00 ATOM 844 QG MET 170-5.386 1.115 2.714 1.00 0.00 ATOM 845 SD MET 170-4.381 0.281 4.499 1.00 0.00 ATOM 846 QE MET 170-3.168-0.974 3.246 1.00 0.00 ATOM 847 CE MET 170-3.372-0.764 3.456 1.00 0.00 ATOM 848 1HE MET 170-2.824-0.151 2.755 1.00 0.00 ATOM 849 2HE MET 170-4.004-1.452 2.914 1.00 0.00 ATOM 850 3HE MET 170-2.677-1.320 4.069 1.00 0.00 ATOM 851 C MET 170-4.775 5.150 3.526 1.00 0.00 ATOM 852 O MET 170-5.212 5.590 4.589 1.00 0.00 ATOM 853 N LEU 171-4.671 5.884 2.430 1.00 0.00 ATOM 854 H LEU 171-4.303 5.479 1.617 1.00 0.00 ATOM 855 CA LEU 171-5.070 7.286 2.410 1.00 0.00 ATOM 856 HA LEU 171-5.304 7.575 3.423 1.00 0.00 ATOM 857 CB LEU 171-3.918 8.154 1.902 1.00 0.00 ATOM 858 1HB LEU 171-3. 990 9.123 2.372 1.00 0.00 ATOM 859 2HB LEU 171-4.032 8.282 0.833 1.00 0.00 ATOM 860 QB LEU 171-4.011 8.703 1.603 1.00 0.00 ATOM 861 CG LEU 171-2.525 7.594 2.175 1.00 0.00 ATOM 862 HG LEU 171-2.603 6.774 2.873 1.00 0.00 ATOM 863 QD1 LEU 171-1.756 6.934 0.591 1.00 0.00 ATOM 864 QD2 LEU 171-1.427 8.910 2.945 1.00 0.00 ATOM 865 CD1 LEU 171-1.904 7.059 0.894 1.00 0.00 ATOM 866 1HD1 LEU 171-2.174 6.022 0.768 1.00 0.00 ATOM 867 2HD1 LEU 171-0.828 7.146 0.953 1.00 0.00 ATOM 868 3HD1 LEU 171-2.266 7.632 0.052 1.00 0.00 ATOM 869 CD2 LEU 171-1.639 8.659 2.797 1.00 0.00 ATOM 870 1HD2 LEU 171-1.360 9.381 2.044 1.00 0.00 ATOM 871 2HD2 LEU 171-0.748 8.194 3.198 1.00 0.00 ATOM 872 3HD2 LEU 171-2.174 9.154 3.593 1.00 0.00

ATOM 873 QQD LEU 171-1.591 7.922 1.768 1.00 0.00 ATOM 874 C LEU 171-6.300 7.505 1.543 1.00 0.00 ATOM 875 O LEU 171-6.989 6.550 1.179 1.00 0.00 ATOM 876 N LEU 172-6.552 8.778 1.223 1.00 0.00 ATOM 877 H LEU 172-5.944 9.470 1.557 1.00 0.00 ATOM 878 CA LEU 172-7.690 9.190 0.397 1.00 0.00 ATOM 879 HA LEU 172-7.818 10.254 0.526 1.00 0.00 ATOM 880 CB LEU 172-7.402 8.908-1.081 1.00 0.00 ATOM 881 1HB LEU 172-8.215 8.313-1.473 1.00 0.00 ATOM 882 2HB LEU 172-6.493 8.328-1.145 1.00 0.00 ATOM 883 QB LEU 172-7.354 8.321-1.309 1.00 0.00 ATOM 884 CG LEU 172-7.247 10.148-1.966 1.00 0.00 ATOM 885 HG LEU 172-8.172 10.705-1.961 1.00 0.00 ATOM 886 QD1 LEU 172-5.889 11.269-1.308 1.00 0.00 ATOM 887 QD2 LEU 172-6.873 9.650-3.738 1.00 0.00 ATOM 888 CD1 LEU 172-6.151 11.055-1.434 1.00 0.00 ATOM 889 1HD1 LEU 172-5. 312 10.453-1.110 1.00 0.00 ATOM 890 2HD1 LEU 172-6.528 11.627-0.600 1.00 0.00 ATOM 891 3HD1 LEU 172-5.828 11.727-2.216 1.00 0.00 ATOM 892 CD2 LEU 172-6.946 9.745-3.399 1.00 0.00 ATOM 893 1HD2 LEU 172-7.494 8.848-3.646 1.00 0.00 ATOM 894 2HD2 LEU 172-5.887 9.559-3.504 1.00 0.00 ATOM 895 3HD2 LEU 172-7.238 10.542-4.066 1.00 0.00 ATOM 896 QQD LEU 172-6.381 10.460-2.523 1.00 0.00 ATOM 897 C LEU 172-8.984 8.492 0.818 1.00 0.00 ATOM 898 O LEU 172-9.563 7.734 0.045 1.00 0.00 ATOM 899 N PRO 173-9.463 8.734 2.050 1.00 0.00 ATOM 900 CD PRO 173-8.856 9.628 3.056 1.00 0.00 ATOM 901 CA PRO 173-10.693 8.109 2.537 1.00 0.00 ATOM 902 HA PRO 173-10.649 7.034 2.447 1.00 0.00 ATOM 903 CB PRO 173-10.738 8.497 4.018 1.00 0.00 ATOM 904 1HB PRO 173-10.329 7.695 4.614 1.00 0.00 ATOM 905 2HB PRO 173-11.762 8.681 4.310 1.00 0.00 ATOM 906 QB PRO 173-11.045 8.188 4.462 1.00 0.00 ATOM 907 CG PRO 173-9.910 9.732 4.124 1.00 0.00 ATOM 908 1HG PRO 173-9.450 9.782 5.100 1.00 0.00 ATOM 909 2HG PRO 173-10.528 10.602 3.955 1.00 0.00 ATOM 910 QG PRO 173-9.989 10.192 4.528 1.00 0.00 ATOM 911 1HD PRO 173-7.952 9.195 3.459 1.00 0.00 ATOM 912 2HD PRO 173-8.652 10.600 2.632 1.00 0.00 ATOM 913 QD PRO 173-8.302 9.898 3.046 1.00 0.00 ATOM 914 C PRO 173-11.930 8.624 1.810 1.00 0.00 ATOM 915 O PRO 173-12.188 9.827 1.772 1.00 0.00 ATOM 916 N CYS 174-12.694 7.709 1.237 1.00 0.00 ATOM 917 H CYS 174-12.442 6.763 1.303 1.00 0.00 ATOM 918 CA CYS 174-13.906 8.080 0.524 1.00 0.00 ATOM 919 HA CYS 174-13.889 9.151 0.381 1.00 0.00 ATOM 920 CB CYS 174-13.970 7.395-0.837 1.00 0.00 ATOM 921 1HB CYS 174-13.318 7.914-1.523 1.00 0.00 ATOM 922 2HB CYS 174-14.984 7.445-1.205 1.00 0.00 ATOM 923 QB CYS 174-14.151 7.680-1.364 1.00 0.00 ATOM 924 SG CYS 174-13.476 5.643-0.817 1.00 0.00 ATOM 925 C CYS 174-15.128 7.717 1.351 1.00 0.00 ATOM 926 O CYS 174-16.202 8.289 1.180 1.00 0.00 ATOM 927 N GLY 175-14.948 6.772 2.261 1.00 0.00 ATOM 928 H GLY 175-14.060 6.361 2.360 1. 00 0-. 00 ATOM 929 CA GLY 175-16.029 6.354 3.125 1.00 0.00 ATOM 930 1HA GLY 175-16.378 5.381 2.813 1.00 0.00 ATOM 931 2HA GLY 175-16.839 7.066 3.044 1.00 0.00 ATOM 932 QA GLY 175-16.608 6.224 2.929 1.00 0.00 ATOM 933 C GLY 175-15.570 6.280 4.561 1. 00 0. 00 ATOM 934 O GLY 175-14.434 6.638 4.859 1. 00 0. 00 ATOM 935 N ILE 176-16.435 5.809 5. 453 1. 00 0. 00 ATOM 936 H ILE 176-17.326 5.530 5.159 1. oo o. oo ATOM 937 CA ILE 176-16.075 5.688 6.861 1.00 0.00 ATOM 938 HA ILE 176-15.695 6.647 7.187 1.00 0.00 ATOM 939 CB ILE 176-17.305 5.324 7.737 1.00 0.00 ATOM 940 HB ILE 176-17.873 6.228 7. 900 1. 00 0. 00 ATOM 941 QG2 ILE 176-18.426 4.094 6.856 1.00 0.00 ATOM 942 CG2 ILE 176-18.212 4.329 7.022 1.00 0.00 ATOM 943 1HG2 ILE 176-18.817 4.849 6.296 1. oo 0.00 ATOM 944 2HG2 ILE 176-18.853 3.847 7.747 1.00 0.00

ATOM 945 3HG2 ILE 176-17.609 3.584 6.525 1.00 0.00 ATOM 946 CG1 ILE 176-16.871 4.765 9.098 1.00 0.00 ATOM 947 1HG1 ILE 176-16.281 5.509 9.614 1.00 0.00 ATOM 948 2HG1 ILE 176-16.270 3.881 8.942 1.00 0.00 ATOM 949 QG1 ILE 176-16.275 4.695 9.278 1.00 0.00 ATOM 950 QD1 ILE 176-18.305 4.294 10.207 1.00 0.00 ATOM 951 CD1 ILE 176-18.030 4.384 9.994 1.00 0.00 ATOM 952 1HD1 ILE 176-18.275 5.215 10.639 1.00 0.00 ATOM 953 2HD1 ILE 176-17. 754 3.530 10.594 1.00 0.00 ATOM 954 3HD1 ILE 176-18.887 4.135 9.386 1.00 0.00 ATOM 955 C ILE 176-14.967 4.643 7.024 1.00 0.00 ATOM 956 O ILE 176-13.986 4.868 7.733 1.00 0.00 ATOM 957 N ASP 177-15.127 3.515 6.336 1.00 0.00 ATOM 958 H ASP 177-15.921 3.411 5.777 1.00 0.00 ATOM 959 CA ASP 177-14.142 2.441 6.371 1.00 0.00 ATOM 960 HA ASP 177-13.297 2.783 6.953 1.00 0.00 ATOM 961 CB ASP 177-14.724 1.186 7.029 1.00 0.00 ATOM 962 1HB ASP 177-15.292 0.634 6.298 1.00 0.00 ATOM 963 2HB ASP 177-15.375 1.481 7.838 1.00 0.00 ATOM 964 QB ASP 177-15.333 1.058 7.068 1.00 0.00 ATOM 965 CG ASP 177-13.650 0.272 7.591 1.00 0.00 ATOM 966 OD1 ASP 177-14.004-0.811 8.098 1.00 0.00 ATOM 967 OD2 ASP 177-12.455 0.633 7.516 1.00 0.00 ATOM 968 C ASP 177-13.664 2.119 4.955 1.00 0.00 ATOM 969 O ASP 177-13.199 1.014 4.667 1.00 0.00 ATOM 970 N LYS+ 178-13.776 3.096 4.064 1.00 0.00 ATOM 971 H LYS+ 178-14.143 3.959 4.345 1.00 0.00 ATOM 972 CA LYS+ 178-13.344 2.915 2.683 1.00 0.00 ATOM 973 HA LYS+ 178-12.877 1.943 2.611 1.00 0.00 ATOM 974 CB LYS+ 178-14.519 2.983 1.702 1.00 0.00 ATOM 975 1HB LYS+ 178-14.149 2.759 0.711 1.00 0.00 ATOM 976 2HB LYS+ 178-14.905 3.987 1.705 1.00 0.00 ATOM 977 QB LYS+ 178-14.527 3.373 1.208 1.00 0.00 ATOM 978 CG LYS+ 178-15.666 2.023 2.015 1.00 0.00 ATOM 979 1HG LYS+ 178-16.415 2.112 1.241 1.00 0.00 ATOM 980 2HG LYS+ 178-16.098 2.294 2.966 1.00 0.00 ATOM 981 QG LYS+ 178-16.256 2.203 2.104 1.00 0.00 ATOM 982 CD LYS+ 178-15.195 0.574 2.087 1.00 0.00 ATOM 983 1HD LYS+ 178-15.377 0.199 3.085 1.00 0.00 ATOM 984 2HD LYS+ 178-14.135 0.542 1.881 1.00 0.00 ATOM 985 QD LYS+ 178-14.756 0.371 2.483 1.00 0.00 ATOM 986 CE LYS+ 178-15.921-0.314 1.083 1.00 0.00 ATOM 987 1HE LYS+ 178-15.662 0. 010 0.083 1.00 0.00 ATOM 988 2HE LYS+ 178-16.986-0.205 1.230 1.00 0.00 ATOM 989 QE LYS+ 178-16.324-0.097 0.657 1.00 0.00 ATOM 990 NZ LYS+ 178-15.556-1.754 1.239 1.00 0.00 ATOM 991 1HZ LYS+ 178-15.026-2.090 0.395 1.00 0.00 ATOM 992 2HZ LYS+ 178-16.410-2.334 1.340 1.00 0.00 ATOM 993 3HZ LYS+ 178-14.955-1.893 2.081 1.00 0.00 ATOM 994 QZ LYS+ 178-15.463-2.105 1.272 1.00 0.00 ATOM 995 C LYS+ 178-12.310 3.961 2.318 1.00 0. 00 ATOM 996 O LYS+ 178-12.446 5.136 2.660 1.00 0.00 ATOM 997 N PHE 179-11.275 3.520 1.630 1.00 0.00 ATOM 998 H PHE 179-11.232 2.572 1.393 1.00 0.00 ATOM 999 CA PHE 179-10.193 4.398 1.227 1.00 0.00 ATOM 1000 HA PHE 179-10.477 5.412 1.464 1.00 0.00 ATOM 1001 CB PHE 179-8.914 4.047 1. 987 1.00 0.00 ATOM 1002 1HB PHE 179-8.189 4.806 1.796 1.00 0.00 ATOM 1003 2HB PHE 179-8.531 3.108 1.622 1.00 0.00 ATOM 1004 QB PHE 179-8.360 3.957 1.709 1.00 0.00 ATOM 1005 QD PHE 179-9.117 3.923 3.646 1.00 0.00 ATOM 1006 QE PHE 179-9.435 3.752 6.079 1.00 0.00 ATOM 1007 QR PHE 179-9.340 3.803 5. 350 1.00 0.00 ATOM 1008 CG PHE 179-9.096 3.935 3. 479 1.00 0.00 ATOM 1009 CD1 PHE 179-9.591 2.771 4.049 1.00 0.00 ATOM 1010 1HD PHE 179-9.840 1.934 3.413 1.00 0.00 ATOM 1011 CE1 PHE 179-9.771 2.672 5.415 1.00 0.00 ATOM 1012 1HE PHE 179-10.161 1.761 5.845 1.00 0.00 ATOM 1013 CZ PHE 179-9.454 3.741 6.230 1.00 0.00 ATOM 1014 HZ PHE 179-9.596 3.666 7.299 1.00 0.00 ATOM 1015 CE2 PHE 179-8.958 4.905 5.677 1.00 0.00 ATOM 1016 2HE PHE 179-8.710 5.743 6.312 1.00 0.00

ATOM 1017 CD2 PHE 179-8.783 5.000 4.309 1.00 0.00 ATOM 1018 2HD PHE 179-8.395 5.911 3.878 1.00 0.00 ATOM 1019 C PHE 179-9.930 4.290-0.261 1.00 0.00 ATOM 1020 O PHE 179-10.598 3.536-0.967 1.00 0.00 ATOM 1021 N ARG+ 180-8.938 5.038-0.722 1.00 0.00 ATOM 1022 H ARG+ 180-8. 441 5.608-0.096 1.00 0.00 ATOM 1023 CA ARG+ 180-8.554 5.034-2.125 1.00 0.00 ATOM 1024 HA ARG+ 180-8.996 4.166-2.594 1.00 0.00 ATOM 1025 CB ARG+ 180-9. 062 6.301-2.825 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.829 6.228-3.878 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.544 7.153-2.413 1.00 0.00 ATOM 1028 QB ARG+ 180-8.686 6.691-3.145 1.00 0.00 ATOM 1029 CG ARG+ 180-10.556 6.540-2.683 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.715 7.480-2.176 1.00 0.00 ATOM 1031 2HG ARG+ 180-10.982 5.736-2.097 1.00 0.00 ATOM 1032 QG ARG+ 180-10.848 6.608-2.136 1.00 0.00 ATOM 1033 CD ARG+ 180-11.243 6.577-4.038 1.00 0.00 ATOM 1034 1HD ARG+ 180-11.979 5.786-4.069 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.502 6.402-4.805 1.00 0.00 ATOM 1036 QD ARG+ 180-11.240 6.094-4.437 1.00 0.00 ATOM 1037 NE ARG+ 180-11.906 7.854-4.301 1.00 0.00 ATOM 1038 HE ARG+ 180-11.701 8.604-3.700 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.752 8.048-5.316 1.00 0.00 ATOM 1040 NH1 ARG+ 180-13.039 7.043-6.138 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.622 6.143-5.996 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.657 7.183-6.912 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.139 6.663-6.454 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.303 9.241-5.509 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-13.087 10.001-4.895 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.929 9.388-6.278 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13.508 9.695-5.586 1.00 0.00 ATOM 1048 C ARG+ 180-7.036 4.963-2.270 1.00 0.00 ATOM 1049 O ARG+ 180-6.520 4.607-3.323 1.00 0.00 ATOM 1050 N GLY 181-6.321 5.323-1.217 1.00 0.00 ATOM 1051 H GLY 181-6.775 5.607-0.395 1.00 0.00 ATOM 1052 CA GLY 181-4.874 5.315-1.283 1.00 0.00 ATOM 1053 1HA GLY 181-4.506 6.265-0.918 1.00 0.00 ATOM 1054 2HA GLY 181-4.577 5.205-2.315 1.00 0.00 ATOM 1055 QA GLY 181-4.541 5.735-1.616 1.00 0.00 ATOM 1056 C GLY 181-4.242 4.206-0.479 1.00 0.00 ATOM 1057 O GLY 181-4.821 3.723 0.493 1.00 0.00 ATOM 1058 N VAL 182-3.045 3.808-0.889 1.00 0.00 ATOM 1059 H VAL 182-2.645 4.245-1.668 1.00 0.00 ATOM 1060 CA VAL 182-2.296 2.754-0.219 1.00 0.00 ATOM 1061 HA VAL 182-2.629 2.700 0.811 1.00 0.00 ATOM 1062 CB VAL 182-2. 505 1.366-0.884 1.00 0.00 ATOM 1063 HB VAL 182-1.715 1. 221-1. 607 1.00 0.00 ATOM 1064 QG1 VAL 182-2. 372 0.001 0.395 1.00 0.00 ATOM 1065 QG2 VAL 182-4.155 1.250-1.786 1.00 0.00 ATOM 1066 CG1 VAL 182-2.398 0.262 0.150 1.00 0.00 ATOM 1067 1HG1 VAL 182-1.509-0.321-0.038 1. 00 0.00 ATOM 1068 2HG1 VAL 182-3.267-0.375 0.085 1.00 0.00 ATOM 1069 3HG1 VAL 182-2.342 0.698 1.137 1.00 0.00 ATOM 1070 CG2 VAL 182-3.840 1.272-1.614 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.752 1.729-2.588 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.600 1.785-1.043 1.00 0.00 ATOM 1073 3HG2 VAL 182-4. 115 0.234-1.727 1.00 0.00 ATOM 1074 QQG VAL 182-3. 264 0.625-0.695 1.00 0.00 ATOM 1075 C VAL 182-0.800 3.077-0.245 1.00 0.00 ATOM 1076 O VAL 182-0.231 3.297-1.313 1.00 0.00 ATOM 1077 N GLU 183-0.169 3.090 0.924 1.00 0.00 ATOM 1078 H GLU 183-0.676 2.894 1.746 1.00 0.00 ATOM 1079 CA GLU 183 1.264 3.368 1.024 1.00 0.00 ATOM 1080 HA GLU 183 1.676 3.363 0.023 1.00 0.00 ATOM 1081 CB GLU 183 1.518 4.737 1.662 1.00 0.00 ATOM 1082 1HB GLU 183 1.514 5.489 0.887 1.00 0.00 ATOM 1083 2HB GLU 183 2.492 4.725 2.129 1.00 0.00 ATOM 1084 QB GLU 183 2.003 5.107 1.508 1.00 0.00 ATOM 1085 CG GLU 183 0.503 5.140 2.716 1.00 0.00 ATOM 1086 1HG GLU 183 0.263 4.276 3.318 1.00 0.00 ATOM 1087 2HG GLU 183-0.389 5.498 2.225 1.00 0. 00 ATOM 1088 QG GLU 183-0.063 4.887 2.772 1.00 0.00

ATOM 1089 CD GLU 183 1.028 6.231 3.622 1.00 0.00 ATOM 1090 OE1 GLU 183 0.372 6.519 4.642 1.00 0.00 ATOM 1091 OE2 GLU 183 2.096 6.800 3.306 1.00 0.00 ATOM 1092 C GLU 183 1.938 2.275 1.841 1.00 0.00 ATOM 1093 0GLU 183 1.911 2.292 3.064 1.00 0.00 ATOM 1094 N PHE 184 2.499 1.297 1.162 1.00 0.00 ATOM 1095 H PHE 184 2.462 1.311 0.188 1.00 0.00 ATOM 1096 CA PHE 184 3.121 0.171 1.840 1.00 0.00 ATOM 1097 HA PHE 184 2.983 0.318 2.898 1.00 0.00 ATOM 1098 CB PHE 184 2.428-1.134 1.435 1.00 0.00 ATOM 1099 1HB PHE 184 1.533-1.259 2.027 1.00 0.00 ATOM 1100 2HB PHE 184 3.095-1.959 1.640 1.00 0.00 ATOM 1101 QB PHE 184 2.314-1.609 1.834 1.00 0.00 ATOM 1102 QD PHE 184 1.994-1.221-0.193 1.00 0.00 ATOM 1103 QE PHE 184 1.353-1.392-2.559 1.00 0.00 ATOM 1104 QR PHE 184 1.544-1.342-1.849 1.00 0.00 ATOM 1105 CG PHE 184 2.040-1.212-0.026 1.00 0.00 ATOM 1106 CD1 PHE 184 2.693-2.086-0.878 1.00 0.00 ATOM 1107 1HD PHE 184 3.492-2.700-0.493 1.00 0.00 ATOM 1108 CE1 PHE 184 2.333-2.185-2.207 1.00 0.00 ATOM 1109 1HE PHE 184 2.852-2.874-2.857 1.00 0.00 ATOM 1110 CZ PHE 184 1.314-1.404-2.705 1.00 0.00 ATOM 1111 HZ PHE 184 1.028-1.486-3.743 1.00 0.00 ATOM 1112 CE2 PHE 184 0.654-0.524-1.874 1.00 0.00 ATOM 1113 2HE PHE 184-0. 146 0.090-2.261 1.00 0.00 ATOM 1114 CD2 PHE 184 1.014-0.432-0.542 1.00 0.00 ATOM 1115 2HD PHE 184 0.495 0.258 0.107 1.00 0.00 ATOM 1116 C PHE 184 4.608 0.056 1.557 1.00 0.00 ATOM 1117 O PHE 184 5.056 0.220 0.426 1.00 0.00 ATOM 1118 N VAL 185 5.364-0.259 2.598 1.00 0.00 ATOM 1119 H VAL 185 4.938-0.393 3.473 1.00 0.00 ATOM 1120 CA VAL 185 6.799-0.434 2.482 1.00 0.00 ATOM 1121 HA VAL 185 7.105-0.091 1.503 1.00 0.00 ATOM 1122 CB VAL 185 7.561 0.379 3.556 1.00 0.00 ATOM 1123 HB VAL 185 7.735-0.263 4.412 1.00 0.00 ATOM 1124 QG1 VAL 185 9.221 0.953 2.904 1.00 0.00 ATOM 1125 QG2 VAL 185 6.555 1.858 4.133 1.00 0.00 ATOM 1126 CG1 VAL 185 8.903 0.842 3.027 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.126 0.326 2.106 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.669 0.627 3.758 1.00 0.00 ATOM 1129 3HG1 VAL 185 8.868 1.906 2.846 1.00 0.00 ATOM 1130 CG2 VAL 185 6.747 1.575 4.021 1.00 0.00 ATOM 1131 1HG2 VAL 185 7.015 2.443 3.438 1.00 0.00 ATOM 1132 2HG2 VAL 185 6.953 1.764 5.065 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.695 1.366 3.894 1.00 0.00 ATOM 1134 QQG VAL 185 7.888 1.406 3.518 1.00 0.00 ATOM 1135 C VAL 185 7.141-1.918 2.621 1.00 0.00 ATOM 1136 0 VAL 185 7.072-2.483 3.710 1.00 0.00 ATOM 1137 N CYS 186 7.486-2. 558 1.512 1.00 0.00 ATOM 1138 H CYS 186 7.511-2.067 0.659 1.00 0.00 ATOM 1139 CA CYS 186 7.817-3. 978 1.535 1.00 0.00 ATOM 1140 HA CYS 186 7.598-4.346 2.529 1.00 0.00 ATOM 1141 CB CYS 186 6.959-4.756 0.529 1.00 0.00 ATOM 1142 1HB CYS 186 5.948-4.811 0.905 1.00 0.00 ATOM 1143 2HB CYS 186 7.353-5.756 0.437 1.00 0.00 ATOM 1144 QB CYS 186 6.651-5.283 0.671 1.00 0.00 ATOM 1145 SG CYS 186 6.887-4.045-1.145 1.00 0.00 ATOM 1146 C CYS 186 9.299-4.194 1.254 1.00 0.00 ATOM 1147 O CYS 186 9.835-3.663 0.290 1.00 0.00 ATOM 1148 N CYS 187 9.962-4.975 2.095 1.00 0.00 ATOM 1149 H CYS 187 9.486-5.382 2.852 1.00 0.00 ATOM 1150 CA CYS 187 11.389-5.237 1.918 1.00 0.00 ATOM 1151 HA CYS 187 11.812-4.401 1.385 1.00 0.00 ATOM 1152 CB CYS 187 12.096-5.373 3.270 1.00 0.00 ATOM 1153 1HB CYS 187 12.897-6.093 3.174 1.00 0.00 ATOM 1154 2HB CYS 187 11.388-5.730 4.003 1.00 0.00 ATOM 1155 QB CYS 187 12.143-5.911 3.589 1.00 0.00 ATOM 1156 SG CYS 187 12.814-3.826 3.905 1.00 0.00 ATOM 1157 C CYS 187 11.627-6.497 1.113 1.00 0.00 ATOM 1158 0 CYS 187 10.882-7.462 1.234 1. 00 0. 00 ATOM 1159 N PRO 188 12.674-6.498 0.271 1.00 0.00 ATOM 1160 CD PRO 188 13.599-5.369 0.058 1. 00 0. 00

ATOM 1161 CA PRO 188 13.010-7.653-0.556 1.00 0.00 ATOM 1162 HA PRO 188 12.171-7.951-1.172 1.00 0.00 ATOM 1163 CB PRO 188 14.150-7.158-1.451 1.00 0.00 ATOM 1164 1HB PRO 188 13.760-6.903-2.424 1.00 0.00 ATOM 1165 2HB PRO 188 14.891-7.940-1.551 1.00 0.00 ATOM 1166 QB PRO 188 14.326-7.421-1.987 1.00 0.00 ATOM 1167 CG PRO 188 14.714-5.962-0.760 1.00 0.00 ATOM 1168 1HG PRO 188 15.059-5.247-1.493 1.00 0.00 ATOM 1169 2HG PRO 188 15.528-6.261-0.120 1.00 0.00 ATOM 1170 QG PRO 188 15.294-5.754-0.806 1.00 0.00 ATOM 1171 1HD PRO 188 13.115-4.571-0.487 1.00 0.00 ATOM 1172 2HD PRO 188 13.980-5.001 1.000 1.00 0.00 ATOM 1173 QD PRO 188 13.548-4.786 0.257 1.00 0.00 ATOM 1174 C PRO 188 13.458-8.847 0.279 1.00 0.00 ATOM 1175 O PRO 188 14.406-8.742 1.072 1.00 0.00 ATOM 1176 N LEU 189 12.769-9.963 0.084 1.00 0.00 ATOM 1177 H LEU 189 12.037-9.959-0.569 1.00 0.00 ATOM 1178 CA LEU 189 13.064-11.200 0.784 1.00 0.00 ATOM 1179 HA LEU 189 13.833-11.000 1.515 1.00 0.00 ATOM 1180 CB LEU 189 11.815-11.731 1.493 1.00 0.00 ATOM 1181 1HB LEU 189 11.150-12.133 0.744 1.00 0.00 ATOM 1182 2HB LEU 189 11.323-10.903 1.981 1.00 0.00 ATOM 1183 QB LEU 189 11.237-11.518 1.363 1.00 0.00 ATOM 1184 CG LEU 189 12.075-12.822 2.534 1.00 0.00 ATOM 1185 HG LEU 189 12.909-13.428 2.208 1.00 0.00 ATOM 1186 QD1 LEU 189 12.521-12.064 4.195 1.00 0.00 ATOM 1187 QD2 LEU 189 10.574-13.939 2.704 1.00 0.00 ATOM 1188 CD1 LEU 189 12.436-12.209 3.877 1.00 0.00 ATOM 1189 1HD1 LEU 189 11.690-11.477 4.150 1.00 0.00 ATOM 1190 2HD1 LEU 189 13.402-11.733 3.806 1.00 0.00 ATOM 1191 3HD1 LEU 189 12.471-12.984 4.628 1.00 0.00 ATOM 1192 CD2 LEU 189 10.860-13.726 2.672 1.00 0.00 ATOM 1193 1HD2 LEU 189 10.289-13.430 3.539 1.00 0.00 ATOM 1194 2HD2 LEU 189 11.186-14.749 2.785 1.00 0.00 ATOM 1195 3HD2 LEU 189 10.246-13.639 1.788 1.00 0.00 ATOM 1196 QQD LEU 189 11.548-13.002 3.450 1.00 0.00 ATOM 1197 C LEU 189 13.577-12.236-0.208 1.00 0.00 ATOM 1198 OT1 LEU 189 14. 414-13.072 0.187 1.00 0.00 ATOM 1199 OT2 LEU 189 13.139-12.192-1.379 1.00 0.00 TER ENDMDL MODEL 19 ATOM 1 N SER 124 10.305 17. 915 0.192 1.00 0.00 ATOM 2 CA SER 124 9.831 16.547-0.114 1.00 0.00 ATOM 3 HA SER 124 8.856 16.405 0.326 1.00 0.00 ATOM 4 CB SER 124 9.732 16.422-1.632 1.00 0.00 ATOM 5 1HB SER 124 8.803 15.937-1.894 1.00 0.00 ATOM 6 2HB SER 124 10.563 15. 836-2. 000 1.00 0.00 ATOM 7 QB SER 124 9.683 15.887-1.947 1.00 0.00 ATOM 8 OG SER 124 9.768 17.708-2.237 1.00 0.00 ATOM 9 HG SER 124 9.786 17.613-3.198 1.00 0.00 ATOM 10 C SER 124 10.794 15.514 0.446 1.00 0.00 ATOM 11 O SER 124 11.992 15.577 0.182 1.00 0.00 ATOM 12 1HT SER 124 10.266 18.501-0.669 1.00 0.00 ATOM 13 2HT SER 124 11.288 17.882 0.532 1.00 0.00 ATOM 14 3HT SER 124 9.710 18.348 0.924 1.00 0.00 ATOM 15 N ASP 125 10.266 14.577 1.218 1.00 0.00 ATOM 16 H ASP 125 9.303 14.584 1.393 1.00 0.00 ATOM 17 CA ASP 125 11.081 13.533 1.817 1.00 0.00 ATOM 18 HA ASP 125 12.107 13.870 1.825 1.00 0.00 ATOM 19 CB ASP 125 10.630 13.267 3.253 1.00 0.00 ATOM 20 1HB ASP 125 9.963 12.418 3.265 1.00 0.00 ATOM 21 2HB ASP 125 10.112 14.134 3.631 1.00 0.00 ATOM 22 QB ASP 125 10.037 13.276 3.448 1.00 0.00 ATOM 23 CG ASP 125 11.795 12.971 4.167 1.00 0.00 ATOM 24 OD1 ASP 125 12.347 13.927 4.745 1.00 0.00 ATOM 25 OD2 ASP 125 12.157 11.784 4.294 1.00 0.00 ATOM 26 C ASP 125 10.985 12.255 0.993 1.00 0.00 ATOM 27 O ASP 125 10.762 12.305-0.220 1.00 0.00 ATOM 28 N ALA 126 11.149 11.116 1.650 1.00 0.00 ATOM 29 H ALA 126 11.323 11.145 2.620 1.00 0. 00 ATOM 30 CA ALA 126 11.083 9.827 0.976 1.00 0. 00

ATOM 31 HA ALA 126 11.591 9.926 0.029 1.00 0.00 ATOM 32 QB ALA 126 11.983 8.517 1.984 1.00 0.00 ATOM 33 CB ALA 126 11.812 8.768 1.790 1.00 0.00 ATOM 34 1HB ALA 126 11.089 8. 147 2.300 1.00 0.00 ATOM 35 2HB ALA 126 12.450 9.248 2.518 1.00 0.00 ATOM 36 3HB ALA 126 12.411 8.156 1.132 1.00 0.00 ATOM 37 C ALA 126 9.645 9.392 0.720 1.00 0.00 ATOM 38 O ALA 126 8.972 8.878 1.612 1.00 0.00 ATOM 39 N LEU 127 9.185 9.583-0.511 1.00 0.00 ATOM 40 H LEU 127 9.773 9.986-1.180 1.00 0.00 ATOM 41 CA LEU 127 7.833 9.194-0.893 1.00 0.00 ATOM 42 HA LEU 127 7.232 9.161 0.001 1.00 0.00 ATOM 43 CB LEU 127 7.240 10.223-1.868 1.00 0.00 ATOM 44 1HB LEU 127 7.486 9.912-2.873 1.00 0.00 ATOM 45 2HB LEU 127 7.714 11.175-1.682 1.00 0.00 ATOM 46 QB LEU 127 7.600 10.544-2.277 1.00 0.00 ATOM 47 CG LEU 127 5.717 10.424-1.793 1.00 0.00 ATOM 48 HG LEU 127 5.495 11.471-1.941 1.00 0.00 ATOM 49 QD1 LEU 127 4.850 9.458-3.151 1.00 0.00 ATOM 50 QD2 LEU 127 5.049 9.924-0.106 1.00 0.00 ATOM 51 CD1 LEU 127 5.016 9.643-2.892 1.00 0.00 ATOM 52 1HD1 LEU 127 5.007 10.228-3.800 1.00 0.00 ATOM 53 2HD1 LEU 127 4.001 9.430-2.589 1.00 0.00 ATOM 54 3HD1 LEU 127 5.542 8.715-3.065 1.00 0.00 ATOM 55 CD2 LEU 127 5.178 10.020-0.428 1.00 0.00 ATOM 56 1HD2 LEU 127 5.084 8.944-0.383 1.00 0.00 ATOM 57 2HD2 LEU 127 4.208 10.471-0.277 1.00 0.00 ATOM 58 3HD2 LEU 127 5.855 10.355 0.342 1.00 0.00 ATOM 59 QQD LEU 127 4.949 9.691-1.628 1.00 0.00 ATOM 60 C LEU 127 7.856 7.805-1.529 1.00 0.00 ATOM 61 O LEU 127 6.817 7.237-1.867 1.00 0.00 ATOM 62 N LEU 128 9.054 7.258-1.680 1.00 0.00 ATOM 63 H LEU 128 9.844 7.751-1.383 1.00 0.00 ATOM 64 CA LEU 128 9.222 5.940-2.262 1.00 0.00 ATOM 65 HA LEU 128 8.269 5.440-2.231 1.00 0.00 ATOM 66 CB LEU 128 9.682 6. 059-3.720 1.00 0.00 ATOM 67 1HB LEU 128 10.762 6.037-3.736 1.00 0.00 ATOM 68 2HB LEU 128 9.354 7.016-4.101 1.00 0.00 ATOM 69 QB LEU 128 10.058 6.527-3.918 1.00 0.00 ATOM 70 CG LEU 128 9.166 4.964-4.661 1.00 0.00 ATOM 71 HG LEU 128 8.729 4.167-4.076 1.00 0.00 ATOM 72 QD1 LEU 128 7.824 5.651-5.784 1.00 0.00 ATOM 73 QD2 LEU 128 10.572 4.251-5.686 1.00 0.00 ATOM 74 CD1 LEU 128 8.081 5.518-5.569 1.00 0.00 ATOM 75 1HD1 LEU 128 8.526 6.180-6.298 1.00 0.00 ATOM 76 2HD1 LEU 128 7.361 6.066-4.978 1.00 0.00 ATOM 77 3HD1 LEU 128 7.585 4.705-6.076 1.00 0.00 ATOM 78 CD2 LEU 128 10.303 4.386-5.489 1.00 0. 00 ATOM 79 1HD2 LEU 128 10.707 3.517-4.993 1.00 0.00 ATOM 80 2HD2 LEU 128 11.079 5.129-5.602 1.00 0.00 ATOM 81 3HD2 LEU 128 9.931 4.105-6.464 1.00 0.00 ATOM 82 QQD LEU 128 9.198 4.951-5.735 1.00 0.00 ATOM 83 C LEU 128 10.220 5.141-1.428 1.00 0.00 ATOM 84 O LEU 128 10.298 5.334-0.218 1.00 0.00 ATOM 85 N VAL 129 10.959 4.247-2.079 1.00 0.00 ATOM 86 H VAL 129 10.827 4.152-3.043 1.00 0.00 ATOM 87 CA VAL 129 11.953 3.395-1.410 1.00 0.00 ATOM 88 HA VAL 129 11.421 2.656-0.832 1.00 0.00 ATOM 89 CB VAL 129 12.828 2.656-2.449 1.00 0.00 ATOM 90 HB VAL 129 13.421 3.392-2.974 1.00 0.00 ATOM 91 QG1 VAL 129 14.007 1.451-1.612 1.00 0.00 ATOM 92 QG2 VAL 129 11.756 1.760-3.706 1.00 0.00 ATOM 93 CG1VAL 129 13.780 1.681-1.773 1. 00 0. 00 ATOM 94 1HG1 VAL 129 13.244 1.107-1. 031 1. 00 0. 00 ATOM 95 2HG1 VAL 129 14.578 2.231-1.294 1. 00 0. 00 ATOM 96 3HG1 VAL 129 14.198 1.014-2.512 1.00 0.00 ATOM 97 CG2 VAL 129 11.960 1.931-3.466 1.00 0.00 ATOM 98 1HG2 VAL 129 12.236 2.245-4.462 1. 00 0. 00 ATOM 99 2HG2 VAL 129 10.923 2.168-3. 287 1.00 0.00 ATOM 100 3HG2 VAL 129 12.110 0.866-3.370 1. 00 0. 00 ATOM 101 QQG VAL 129 12.881 1.606-2.659 1.00 0.00 ATOM 102 C VAL 129 12.865 4.194-0. 469 1. 00 0. 00

ATOM 103 O VAL 129 13. 659 5.020-0.915 1.00 0.00 ATOM 104 N PRO 130 12.742 3.956 0.854 1.00 0.00 ATOM 105 CD PRO 130 11.809 3.015 1.469 1.00 0.00 ATOM 106 CA PRO 130 13.532 4.638 1.874 1.00 0.00 ATOM 107 HA PRO 130 13.710 5.662 1.613 1.00 0.00 ATOM 108 CB PRO 130 12.634 4.577 3.123 1.00 0.00 ATOM 109 1HB PRO 130 12.301 5.575 3.372 1.00 0.00 ATOM 110 2HB PRO 130 13.199 4.172 3.950 1.00 0.00 ATOM 111 QB PRO 130 12.750 4.874 3.661 1.00 0.00 ATOM 112 CG PRO 130 11.472 3.690 2.772 1.00 0.00 ATOM 113 1HG PRO 130 10.579 4.289 2.660 1.00 0.00 ATOM 114 2HG PRO 130 11.329 2.951 3.546 1.00 0.00 ATOM 115 QG PRO 130 10.954 3.620 3.103 1.00 0.00 ATOM 116 1HD PRO 130 10.924 2.897 0.862 1.00 0.00 ATOM 117 2HD PRO 130 12.282 2.059 1.644 1.00 0.00 ATOM 118 QD PRO 130 11.603 2.478 1.253 1.00 0.00 ATOM 119 C PRO 130 14.872 3.956 2.141 1.00 0.00 ATOM 120 O PRO 130 15.884 4.283 1.528 1.00 0.00 ATOM 121 N ASP 131 14.855 3.020 3.076 1.00 0.00 ATOM 122 H ASP 131 14. 012 2.833 3.523 1.00 0.00 ATOM 123 CA ASP 131 16.054 2.278 3.466 1.00 0.00 ATOM 124 HA ASP 131 16.900 2.944 3.390 1.00 0.00 ATOM 125 CB ASP 131 15.910 1.813 4.924 1.00.0.00 ATOM 126 1HB ASP 131 15.149 1.049 4.976 1.00 0.00 ATOM 127 2HB ASP 131 15.608 2.653 5.531 1.00 0.00 ATOM 128 QB ASP 131 15.378 1.851 5.254 1.00 0.00 ATOM 129 CG ASP 131 17.191 1.252 5.504 1.00 0.00 ATOM 130 OD1 ASP 131 17.124 0.610 6.572 1.00 0.00 ATOM 131 OD2 ASP 131 18.260 1.428 4.892 1.00 0.00 ATOM 132 C ASP 131 16.281 1.079 2.539 1.00 0.00 ATOM 133 O ASP 131 16.764 1.232 1.420 1.00 0.00 ATOM 134 N LYS+ 132 15.922-0.115 3.002 1.00 0.00 ATOM 135 H LYS+ 132 15.538-0.184 3.899 1.00 0.00 ATOM 136 CA LYS+ 132 16.090-1.324 2.194 1.00 0. 00 ATOM 137 HA LYS+ 132 16.635-1.049 1.302 1.00 0.00 ATOM 138 CB LYS+ 132 16.880-2.396 2.952 1.00 0.00 ATOM 139 1HB LYS+ 132 17.423-2.994 2.235 1.00 0.00 ATOM 140 2HB LYS+ 132 16.183-3.031 3.479 1.00 0.00 ATOM 141 QB LYS+ 132 16.803-3.012 2.857 1.00 0.00 ATOM 142 CG LYS+ 132 17.873-1.840 3.959 1.00 0.00 ATOM 143 1HG LYS+ 132 17.711-0.775 4.059 1.00 0.00 ATOM 144 2HG LYS+ 132 18.874-2.022 3.599 1.00 0.00 ATOM 145 QG LYS+ 132 18.292-1.398 3.829 1.00 0.00 ATOM 146 CD LYS+ 132 17.708-2.496 5.320 1.00 0.00 ATOM 147 1HD LYS+ 132 17.589-3.561 5.185 1.00 0.00 ATOM 148 2HD LYS+ 132 16.828-2.091 5.799 1.00 0.00 ATOM 149 QD LYS+ 132 17.208-2.826 5.492 1.00 0.00 ATOM 150 CE LYS+ 132 18.913-2.239 6.209 1.00 0.00 ATOM 151 1HE LYS+ 132 19.733-2.852 5.864 1.00 0.00 ATOM 152 2HE LYS+ 132 18.660-2.513 7.222 1.00 0.00 ATOM 153 QE LYS+ 132 19.196-2.682 6.543 1.00 0. 00 ATOM 154 NZ LYS+ 132 19.327-0.809 6.182 1.00 0.00 ATOM 155 1HZ LYS+ 132 20.111-0.643 6.840 1.00 0.00 ATOM 156 2HZ LYS+ 132 18.519-0.194 6.458 1.00 0.00 ATOM 157 3HZ LYS+ 132 19.624-0.534 5.224 1.00 0.00 ATOM 158 QZ LYS+ 132 19.418-0.457 6.174 1.00 0.00 ATOM 159 C LYS+ 132 14.737-1.889 1.786 1.00 0.00 ATOM 160 O LYS+ 132 14.655-2.877 1.059 1.00 0.00 ATOM 161 N CYS 133 13.677-1.259 2.259 1.00 0.00 ATOM 162 H CYS 133 13.804-0.478 2.831 1.00 0.00 ATOM 163 CA CYS 133 12.329-1.697 1.939 1.00 0.00 ATOM 164 HA CYS 133 12.367-2.749 1.699 1.00 0.00 ATOM 165 CB CYS 133 11.391-1. 482 3.130 1. 00 0. 00 ATOM 166 1HB CYS 133 10.400-1.263 2.756 1.00 0.00 ATOM 167 2HB CYS 133 11.741-0.638 3.699 1.00 0.00 ATOM 168 QB CYS 133 11.070-0.950 3.228 1. 00 o. oo ATOM 169 SG CYS 133 11.246-2.892 4.277 1.00 0. 00 ATOM 170 C CYS 133 11.809-0.930 0. 733 1. 00 o. oo ATOM 171 O CYS 133 12.225 0.196 0.482 1. 00 0. 00 ATOM 172 N LYS+ 134 10.896-1.533-0.004 1.00 0.00 ATOM 173 H LYS+ 134 10.587-2.429 0.251 1. 00 0. 00 ATOM 174 CA LYS+ 134 10.324-0.897-1. 175 1. 00 0. 00

ATOM 175 HA LYS+ 134 11.021-0.147-1.520 1.00 0.00 ATOM 176 CB LYS+ 134 10.094-1.922-2.288 1.00 0.00 ATOM 177 1HB LYS+ 134 9.103-2.339-2.177 1.00 0.00 ATOM 178 2HB LYS+ 134 10.821-2.715-2.186 1.00 0.00 ATOM 179 QB LYS+ 134 9.962-2.527-2.181 1.00 0.00 ATOM 180 CG LYS+ 134 10.214-1.341-3.688 1.00 0.00 ATOM 181 1HG LYS+ 134 11.175-1.619-4.099 1.00 0.00 ATOM 182 2HG LYS+ 134 10.144-0.266-3.629 1.00 0.00 ATOM 183 QG LYS+ 134 10.659-0.942-3.864 1.00 0.00 ATOM 184 CD LYS+ 134 9.116-1.859-4.604 1.00 0.00 ATOM 185 1HD LYS+ 134 8.301-2.231-3.999 1.00 0.00 ATOM 186 2HD LYS+ 134 9.514-2.665-5.205 1.00 0.00 ATOM 187 QD LYS+ 134 8.907-2.448-4.602 1.00 0.00 ATOM 188 CE LYS+ 134 8.593-0.769-5.528 1.00 0.00 ATOM 189 1HE LYS+ 134 7.674-1.112-5.982 1.00 0.00 ATOM 190 2HE LYS+ 134 9.327-0.586-6.299 1.00 0.00 ATOM 191 QE LYS+ 134 8.500-0.849-6.140 1.00 0.00 ATOM 192 NZ LYS+ 134 8.328 0.505-4.796 1.00 0.00 ATOM 193 1HZ LYS+ 134 7.642 1.084-5.323 1.00 0.00 ATOM 194 2HZ LYS+ 134 9.206 1.047-4.685 1.00 0.00 ATOM 195 3HZ LYS+ 134 7.936 0.301-3.852 1.00 0.00 ATOM 196 QZ LYS+ 134 8.261 0.811-4.620 1.00 0.00 ATOM 197 C LYS+ 134 9.017-0.224-0.806 1.00 0.00 ATOM 198 O LYS+ 134 8.044-0.890-0.476 1.00 0.00 ATOM 199 N PHE 135 9.002 1.094-0.857 1.00 0.00 ATOM 200 H PHE 135 9.814 1.574-1.123 1.00 0.00 ATOM 201 CA PHE 135 7.810 1.849-0.511 1.00 0.00 ATOM 202 HA PHE 135 7.228 1.259 0.181 1.00 0.00 ATOM 203 CB PHE 135 8.208 3.165 0.161 1.00 0.00 ATOM 204 1HB PHE 135 8.646 3.816-0.582 1.00 0.00 ATOM 205 2HB PHE 135 8.946 2.959 0.921 1.00 0.00 ATOM 206 QB PHE 135 8.796 3.388 0.170 1.00 0.00 ATOM 207 QD PHE 135 6.959 4.000 0.894 1.00 0.00 ATOM 208 QE PHE 135 5.143 5.246 1.986 1.00 0.00 ATOM 209 QR PHE 135 5.687 4.873 1.659 1.00 0.00 ATOM 210 CG PHE 135 7.083 3.915 0.818 1.00 0.00 ATOM 211 CD1 PHE 135 7.181 5.283 1.013 1.00 0.00 ATOM 212 1HD PHE 135 8.067 5.804 0.680 1.00 0.00 ATOM 213 CE1 PHE 135 6.162 5.985 1.626 1.00 0.00 ATOM 214 1HE PHE 135 6.252 7.052 1.772 1.00 0.00 ATOM 215 CZ PHE 135 5.030 5.323 2.052 1.00 0.00 ATOM 216 HZ PHE 135 4.229 5.870 2.534 1.00 0.00 ATOM 217 CE2 PHE 135 4.920 3.961 1.864 1.00 0.00 ATOM 218 2HE PHE 135 4.034 3.440 2.200 1.00 0.00 ATOM 219 CD2 PHE 135 5.941 3.263 1.251 1.00 0.00 ATOM 220 2HD PHE 135 5.852 2.196 1.107 1.00 0.00 ATOM 221 C PHE 135 6.980 2.118-1.755 1.00 0.00 ATOM 222 O PHE 135 7.482 2 : 636-2. 757 1.00 0.00 ATOM 223 N LEU 136 5.716 1.742-1.685 1.00 0.00 ATOM 224 H LEU 136 5.390 1.319-0.859 1.00 0.00 ATOM 225 CA LEU 136 4. 794 1.919-2.789 1.00 0.00 ATOM 226 HA LEU 136 5.323 2.400-3.596 1.00 0.00 ATOM 227 CB LEU 136 4.252 0.570-3.270 1.00 0.00 ATOM 228 1HB LEU 136 3.453 0.761-3.973 1.00 0.00 ATOM 229 2HB LEU 136 3.836 0.051-2.417 1.00 0.00 ATOM 230 QB LEU 136 3.644 0.406-3.195 1.00 0.00 ATOM 231 CG LEU 136 5.270-0.349-3.943 1.00 0.00 ATOM 232 HG LEU 136 6.089 0.243-4.317 1.00 0.00 ATOM 233 QD1 LEU 136 5.955-1.586-2.705 1.00 0.00 ATOM 234 QD2 LEU 136 4.484-1.248-5.393 1.00 0.00 ATOM 235 CD1 LEU 136 5.825-1.349-2.944 1.00 0.00 ATOM 236 1HD1 LEU 136 6.326-0.822-2.144 1.00 0.00 ATOM 237 2HD1 LEU 136 6.525-2.005-3.438 1.00 0.00 ATOM 238 3HD1 LEU 136 5.013-1.933-2.534 1.00 0.00 ATOM 239 CD2 LEU 136 4.636-1.075-5.116 1.00 0.00 ATOM 240 1HD2 LEU 136 4.966-2.104-5.123 1.00 0.00 ATOM 241 2HD2 LEU 136 4.926-0.596-6.039 1.00 0.00 ATOM 242 3HD2 LEU 136 3.560-1.044-5.018 1.00 0.00 ATOM 243 QQD LEU 136 5.219-1.417-4.049 1.00 0.00 ATOM 244 C LEU 136 3.637 2.802-2.358 1.00 0.00 ATOM 245 O LEU 136 2.553 2.312-2.054 1.00 0.00 ATOM 246 N HIS+ 137 3.868 4.103-2.336 1.00 0.00

ATOM 247 H HIS+ 137 4.751 4.440-2.591 1.00 0.00 ATOM 248 CA HIS+ 137 2.831 5.043-1.952 1.00 0.00 ATOM 249 HA HIS+ 137 2.123 4.519-1.321 1.00 0.00 ATOM 250 CB HIS+ 137 3.437 6.227-1.176 1.00 0.00 ATOM 251 1HB HIS+ 137 4.196 6.691-1.787 1.00 0.00 ATOM 252 2HB HIS+ 137 3.895 5.855-0.272 1.00 0.00 ATOM 253 QB HIS+ 137 4.045 6.273-1.029 1.00 0. 00 ATOM 254 CG HIS+ 137 2.449 7.294-0.780 1.00 0.00 ATOM 255 ND1 HIS+ 137 2.163 7.611 0.531 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.685 8.125-1.534 1.00 0.00 ATOM 257 1HD HIS+ 137 2.539 7.168 1.333 1.00 0.00 ATOM 258 CE1 HIS+ 137 1.271 8.585 0.562 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.959 8.917-0.678 1.00 0.00 ATOM 260 2HD HIS+ 137 1. 654 8.157-2.615 1.00 0.00 ATOM 261 1HE HIS+ 137 0.861 9.032 1.456 1.00 0.00 ATOM 262 2HE HIS+ 137 0.132 9.405-0.932 1.00 0.00 ATOM 263 C HIS+ 137 2.125 5.533-3.207 1.00 0.00 ATOM 264 O HIS+ 137 2.677 6.328-3.971 1.00 0.00 ATOM 265 N GLN 138 0.914 5.049-3.430 1.00 0.00 ATOM 266 H GLN 138 0.524 4.408-2.791 1.00 0.00 ATOM 267 CA GLN 138 0.150 5.440-4.603 1.00 0.00 ATOM 268 HA GLN 138 0.544 6.383-4.951 1.00 0.00 ATOM 269 CB GLN 138 0.298 4.396-5.713 1. 00 0.00 ATOM 270 1HB GLN 138-0.538 4.489-6.391 1.00 0.00 ATOM 271 2HB GLN 138 0.280 3.413-5.270 1.00 0.00 ATOM 272 QB GLN 138-0.129 3.951-5.830 1.00 0.00 ATOM 273 CG GLN 138 1.584 4.535-6.519 1.00 0.00 ATOM 274 1HG GLN 138 2.032 5.492-6.295 1.00 0.00 ATOM 275 2HG GIN 138 1.342 4.489-7.570 1.00 0.00 ATOM 276 QG GLN 138 1.687 4.991-6.932 1.00 0.00 ATOM 277 CD GLN 138 2.592 3.443-6.209 1.00 0.00 ATOM 278 OE1 GLN 138 2.335 2.265-6.444 1.00 0.00 ATOM 279 NE2 GLN 138 3.747 3.825-5.678 1.00 0.00 ATOM 280 1HE2 GLN 138 3.892 4.781-5.512 1.00 0.00 ATOM 281 2HE2 GLN 138 4.407 3.134-5.473 1.00 0.00 ATOM 282 QE2 GLN 138 4.149 3.958-5.492 1.00 0.00 ATOM 283 C GLN 138-1.318 5.625-4.246 1.00 0.00 ATOM 284 O GIN 138-1.896 4.826-3.508 1.00 0.00 ATOM 285 N GLU 139-1.911 6.685-4.769 1.00 0.00 ATOM 286 H GLU 139-1.395 7.285-5.345 1.00 0.00 ATOM 287 CA GLU 139-3.309 6.985-4.504 1.00 0.00 ATOM 288 HA GLU 139-3.605 6.424-3.630 1.00 0.00 ATOM 289 CB GLU 139-3.484 8.478-4.218 1.00 0.00 ATOM 290 1HB GLU 139-4.315 8.606-3.538 1.00 0.00 ATOM 291 2HB GLU 139-3.707 8.987-5.144 1.00 0.00 ATOM 292 QB GLU 139-4.011 8.797-4.341 1.00 0.00 ATOM 293 CG GLU 139-2.260 9.134-3.593 1.00 0.00 ATOM 294 1HG GLU 139-2.111 10.100-4.053 1.00 0.00 ATOM 295 2HG GLU 139-1.399 8.511-3.778 1.00. 0.00 ATOM 296 QG GLU 139-1.755 9.306-3.915 1.00 0.00 ATOM 297 CD GLU 139-2.403 9. 326-2.099 1.00 0. 00 ATOM 298 OE1 GLU 139-1.441 9.815-1.471 1.00 0.00 ATOM 299 OE2 GLU 139-3.474 8.984-1.555 1.00 0.00 ATOM 300 C GLU 139-4.189 6.566-5.678 1.00 0.00 ATOM 301 O GLU 139-4.185 7.205-6.731 1.00 0.00 ATOM 302 N ARG+ 140-4.948 5.497-5.487 1.00 0.00 ATOM 303 H ARG+ 140-4.916 5.036-4.621 1.00 0.00 ATOM 304 CA ARG+ 140-5.846 4.995-6.519 1.00 0.00 ATOM 305 HA ARG+ 140-5.476 5.326-7.478 1.00 0.00 ATOM 306 CB ARG+ 140-5.886 3.460-6.488 1.00 0.00 ATOM 307 1HB ARG+ 140-6.413 3.149-5.597 1.00 0.00 ATOM 308 2HB ARG+ 140-4.874 3.087-6.444 1.00 0.00 ATOM 309 QB ARG+ 140-5.644 3.118-6.020 1. 00 0. 00 ATOM 310 CG ARG+ 140-6. 575 2.831-7.690 1. 00 0. 00 ATOM 311 1HG ARG+ 140-7.554 3.276-7.802 1.00 0.00 ATOM 312 2HG ARG+ 140-6. 677 1.771-7.519 1. 00 0. 00 ATOM 313 QG ARG+ 140-7.116 2.524-7.660 1. 00 0. 00 ATOM 314 CD ARG+ 140-5.784 3.052-8.970 1. 00 0. 00 ATOM 315 1HD ARG+ 140-4.751 3.237-8.713 1.00 0.00 ATOM 316 2HD ARG+ 140-6.188 3.919-9.478 1.00 0.00 ATOM 317 QD ARG+ 140-5.470 3.578-9.095 1.00 0.00 ATOM 318 NE ARG+ 140-5.855 1.900-9.868 1.00 0.00

ATOM 319 HE ARG+ 140-5.479 1.053-9.545 1.00 0.00 ATOM 320 CZ ARG+ 140-6.379 1.951-11.095 1.00 0.00 ATOM 321 NH1 ARG+ 140-6.944 3.069-11.530 1.00 0.00 ATOM 322 1HH1 ARG+ 140-6.984 3.884-10.932 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.343 3.115-12.445 1.00 0.00 ATOM 324 QH1 ARG+ 140-7.164 3.500-11.688 1.00 0.00 ATOM 325 NH2 ARG+ 140-6.361 0.873-11.873 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.954 0.021-11.542 1.00 0.00 ATOM 327 2HH2 ARG+ 140-6.757 0.910-12.791 1.00 0.00 ATOM 328 QH2 ARG+ 140-6.356 0.466-12.166 1.00 0.00 ATOM 329 C ARG+ 140-7. 244 5.563-6.300 1.00 0.00 ATOM 330 O ARG+ 140-8.082 4.938-5.655 1.00 0.00 ATOM 331 N MET 141-7.482 6.758-6.833 1.00 0.00 ATOM 332 H MET 141-6.765 7.204-7.330 1.00 0.00 ATOM 333 CA MET 141-8. 773 7.439-6.688 1.00 0.00 ATOM 334 HA MET 141-9.047 7.405-5.645 1.00 0.00 ATOM 335 CB MET 141-8.627 8.904-7.114 1.00 0.00 ATOM 336 1HB MET 141-8.829 8.977-8.174 1.00 0.00 ATOM 337 2HB MET 141-7.612 9.222-6.928 1.00 0.00 ATOM 338 QB MET 141-8.221 9.100-7.551 1.00 0.00 ATOM 339 CG MET 141-9.563 9.855-6.387 1.00 0.00 ATOM 340 1HG MET 141-9.816 9.424-5.429 1.00 0.00 ATOM 341 2HG MET 141-10.461 9.972-6.975 1.00 0.00 ATOM 342 QG MET 141-10.139 9.698-6.202 1.00 0.00 ATOM 343 SD MET 141-8.837 11.483-6.114 1.00 0.00 ATOM 344 QE MET 141-8.282 12.032-8.119 1.00 0.00 ATOM 345 CE MET 141-8.375 11.940-7.784 1.00 0.00 ATOM 346 1HE MET 141-7. 342 12.255-7.798 1.00 0.00 ATOM 347 2HE MET 141-9.003 12.751-8.122 1.00 0.00 ATOM 348 3HE MET 141-8.501 11.090-8.438 1.00 0.00 ATOM 349 C MET 141-9.883 6. 768-7.510 1.00 0.00 ATOM 350 O MET 141-10.835 7.427-7.935 1.00 0.00 ATOM 351 N ASP 142-9.759 5.468-7.728 1.00 0.00 ATOM 352 H ASP 142-8.984 4.996-7.366 1.00 0.00 ATOM 353 CA ASP 142-10.732 4.720-8.497 1.00 0.00 ATOM 354 HA ASP 142-11.435 5.419-8.923 1.00 0.00 ATOM 355 CB ASP 142-10.030 3.970-9.627 1.00 0.00 ATOM 356 1HB ASP 142-10.772 3.615-10.315 1.00 0.00 ATOM 357 2HB ASP 142-9.501 3.126-9.214 1.00 0.00 ATOM 358 QB ASP 142-10.137 3.371-9.764 1.00 0.00 ATOM 359 CG ASP 142-9.041 4.825-10.389 1.00 0.00 ATOM 360 OD1 ASP 142-9.371 5.260-11.506 1.00 0.00 ATOM 361 OD2 ASP 142-7.914 5.030-9. 885 1.00 0.00 ATOM 362 C ASP 142-11.482 3.718-7.631 1.00 0.00 ATOM 363 O ASP 142-12.709 3.636-7.676 1.00 0.00 ATOM 364 N VAL 143-10.736 2.934-6.863 1.00 0.00 ATOM 365 H VAL 143-9.763 3.031-6,. 882 1.00 0.00 ATOM 366 CA VAL 143-11.336 1.911-6.018 1.00 0.00 ATOM 367 HA VAL 143-12.288 1.647-6.452 1.00 0.00 ATOM 368 CB VAL 143-10.459 0.641-5.975 1.00 0.00 ATOM 369 HB VAL 143-9.812 0.705-5.111 1.00 0.00 ATOM 370 QG1 VAL 143-11.523-0.899-5.796 1.00 0.00 ATOM 371 QG2 VAL 143-9.378 0.514-7.510 1.00 0.00 ATOM 372 CG1 VAL 143-11.321-0.603-5.830 1.00 0.00 ATOM 373 1HG1 VAL 143-11.949-0.509-4.958 1.00 0.00 ATOM 374 2HG1 VAL 143-10.684-1.470-5.722 1.00 0.00 ATOM 375 3HG1 VAL 143-11.937-0.719-6.709 1.00 0.00 ATOM 376 CG2 VAL 143-9.584 0.539-7.217 1.00 0.00 ATOM 377 1HG2 VAL 143-8.563 0.777-6.959 1.00 0.00 ATOM 378 2HG2 VAL 143-9.939 1.232-7.965 1.00 0.00 ATOM 379 3HG2 VAL 143-9.632-0.467-7.607 1.00 0.00 ATOM 380 QQG VAL 143-10.451-0.192-6.653 1.00 0.00 ATOM 381 C VAL 143-11.578 2.433-4.599 1.00 0.00 ATOM 382 O VAL 143-10.957 3.402-4.170 1.00 0.00 ATOM 383 N CYS 144-12.501 1.791-3.886 1.00 0.00 ATOM 384 H CYS 144-12.968 1.031-4.291 1.00 0.00 ATOM 385 CA CYS 144-12. 850 2.192-2.523 1.00 0.00 ATOM 386 HA CYS 144-12.003 2.713-2.090 1.00 0.00 ATOM 387 CB CYS 144-14.061 3.124-2.546 1.00 0.00 ATOM 388 1HB CYS 144-14.604 3.015-1.618 1.00 0.00 ATOM 389 2HB CYS 144-14.705 2.843-3.366 1.00 0.00 ATOM 390 QB CYS 144-14.655 2.929-2.492 1.00 0.00

ATOM 391 SG CYS 144-13.654 4.886-2.746 1.00 0.00 ATOM 392 C CYS 144-13.173 0.976-1.669 1.00 0.00 ATOM 393 O CYS 144-14. 341 0.635-1.473 1.00 0.00 ATOM 394 N GLU 145-12.143 0.320-1.169 1.00 0.00 ATOM 395 H GLU 145-11.233 0.633-1.361 1.00 0.00 ATOM 396 CA GLU 145-12.325-0.865-0.351 1.00 0.00 ATOM 397 HA GLU 145-13.363-1.148-0.416 1.00 0.00 ATOM 398 CB GLU 145-11.473-1.998-0.915 1.00 0.00 ATOM 399 1HB GLU 145-11.246-2.700-0. 130 1.00 0.00 ATOM 400 2HB GLU 145-10.546-1.585-1.294 1.00 0.00 ATOM 401 QB GLU 145-10.896-2.142-0.712 1.00 0.00 ATOM 402 CG GLU 145-12.162-2.750-2.045 1.00 0.00 ATOM 403 1HG GLU 145-12.743-2.047-2.624 1.00 0.00 ATOM 404 2HG GLU 145-12.818-3.492-1.619 1.00 0.00 ATOM 405 QG GLU 145-12.781-2.769-2.121 1.00 0.00 ATOM 406 CD GLU 145-11.189-3.447-2.972 1.00 0.00 ATOM 407 OE1 GLU 145-11.432-3.442-4. 194 1.00 0.00 ATOM 408 OE2 GLU 145-10.190-4.005-2.474 1.00 0.00 ATOM 409 C GLU 145-11. 984-0.594 1.112 1.00 0.00 ATOM 410 O GLU 145-11.651 0.532 1.486 1.00 0.00 ATOM 411 N THR 146-12.098-1.628 1.934 1.00 0.00 ATOM 412 H THR 146-12. 384-2.492 1.573 1.00 0.00 ATOM 413 CA THR 146-11.830-1.521 3.362 1.00 0.00 ATOM 414 HA THR 146-12.180-0.555 3.697 1.00 0.00 ATOM 415 CB THR 146-12.608-2.618 4.094 1.00 0.00 ATOM 416 HB THR 146-11.990-3.504 4.154 1.00 0.00 ATOM 417 QG2 THR 146-13.118-2.152 5.836 1.00 0.00 ATOM 418 OG1 THR 146-13.792-2.944 3.378 1.00 0.00 ATOM 419 1HG THR 146-14.104-3.815 3.652 1.00 0.00 ATOM 420 CG2 THR 146-13.020-2.244 5.499 1.00 0.00 ATOM 421 1HG2 THR 146-14. 056-2.505 5.655 1.00 0.00 ATOM 422 2HG2 THR 146-12.893-1.178 5.642 1.00 0.00 ATOM 423 3HG2 THR 146-12.406-2.775 6.211 1.00 0.00 ATOM 424 C THR 146-10.331-1.629 3.645 1.00 0.00 ATOM 425 O THR 146-9.555-2.018 2.772 1.00 0.00 ATOM 426 N HIS+ 147-9.936-1.279 4.869 1.00 0.00 ATOM 427 H HIS+ 147-10.612-0.973 5.515 1.00 0.00 ATOM 428 CA HIS+ 147-8.532-1.326 5.287 1.00 0.00 ATOM 429 HA HIS+ 147-7.986-0.608 4.693 1.00 0.00 ATOM 430 CB HIS+ 147-8. 417-0.936 6.764 1.00 0.00 ATOM 431 1HB HIS+ 147-8.424-1.833 7.365 1.00 0.00 ATOM 432 2HB HIS+ 147-9.264-0.323 7.034 1.00 0.00 ATOM 433 QB HIS+ 147-8.844-1.078 7.200 1.00 0.00 ATOM 434 CG HIS+ 147-7.173-0.169 7.095 1.00 0.00 ATOM 435 ND1 HIS+ 147-7.156 1.199 7.265 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.900-0.587 7.299 1.00 0.00 ATOM 437 1HD HIS+ 147-7.932 1.800 7.174 1. 00 0.00 ATOM 438 CE1 HIS+ 147-5.928 1.590 7.560 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.146 0.. 526 7.588 1.00 0.00 ATOM 440 2HD HIS+ 147-5.541-1.606 7.230 1.00 0.00 ATOM 441 1HE HIS+ 147-5.617 2.608 7.747 1.00 0.00 ATOM 442 2HE HIS+ 147-4.164 0.553 7.606 1.00 0.00 ATOM 443 C HIS+ 147-7. 919-2.710 5.073 1.00 0.00 ATOM 444 O HIS+ 147-6.741-2.831 4.741 1.00 0.00 ATOM 445 N LEU 148-8.722-3.751 5.269 1.00 0.00 ATOM 446 H LEU 148-9.651-3.593 5.533 1.00 0.00 ATOM 447 CA LEU 148-8.253-5.122 5.101 1.00 0.00 ATOM 448 HA LEU 148-7.304-5.211 5.609 1.00 0.00 ATOM 449 CB LEU 148-9.249-6.100 5.733 1.00 0.00 ATOM 450 1HB LEU 148-10.239-5.852 5.382 1.00 0.00 ATOM 451 2HB LEU 148-9.221-5.966 6.805 1.00 0.00 ATOM 452 QB LEU 148-9.730-5.909 6.094 1.00 0.00 ATOM 453 CG LEU 148-8.989-7.575 5.427 1.00 0.00 ATOM 454 HG LEU 148-8.538-7.656 4.449 1.00 0.00 ATOM 455 QD1 LEU 148-7.794-8.311 6.678 1.00 0.00 ATOM 456 QD2 LEU 148-10.601-8.541 5.409 1.00 0.00 ATOM 457 CD1 LEU 148-8.023-8.169 6.438 1.00 0.00 ATOM 458 1HD1 LEU 148-7. 949-9.235 6.280 1.00 0.00 ATOM 459 2HD1 LEU 148-8.384-7.978 7.438 1.00 0.00 ATOM 460 3HD1 LEU 148-7.049-7.720 6.314 1.00 0.00 ATOM 461 CD2 LEU 148-10.293-8.356 5.412 1.00 0.00 ATOM 462 1HD2 LEU 148-10. 708-8.345 4.416 1.00 0.00

ATOM 463 2HD2 LEU 148-10.992-7.904 6.100 1.00 0.00 ATOM 464 3HD2 LEU 148-10.103-9.376 5.711 1.00 0.00 ATOM 465 QQD LEU 148-9. 198-8. 426 6.043 1.00 0.00 ATOM 466 C LEU 148-8.054-5.456 3.628 1.00 0.00 ATOM 467 O LEU 148-7.146-6.204 3.270 1.00 0.00 ATOM 468 N HIS+ 149-8. 904-4.895 2.779 1.00 0.00 ATOM 469 H HIS+ 149-9.601-4.303 3.123 1.00 0.00 ATOM 470 CA HIS+ 149-8.817-5.136 1.345 1.00 0.00 ATOM 471 HA HIS+ 149-8.814-6.206 1.194 1.00 0.00 ATOM 472 CB HIS+ 149-10.027-4.544 0.633 1.00 0.00 ATOM 473 1HB HIS+ 149-9.724-4.190-0.345 1.00 0.00 ATOM 474 2HB HIS+ 149-10.407-3.714 1.208 1.00 0.00 ATOM 475 QB HIS+ 149-10.066-3.952 0.432 1.00 0.00 ATOM 476 CG HIS+ 149-11.141-5.526 0.440 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.786-6.158 1.485 1.00 0.00 ATOM 478 CD2 HIS+ 149-11.722-5.986-0.691 1.00 0.00 ATOM 479 1HD HIS+ 149-11.581-6.045 2.436 1.00 0.00 ATOM 480 CE1 HIS+ 149-12. 717-6.963 1.000 1.00 0.00 ATOM 481 NE2 HIS+ 149-12. 696-6.875-0.319 1. 00 0.00 ATOM 482 2HD HIS+ 149-11.463-5.699-1.705 1.00 0.00 ATOM 483 1HE HIS+ 149-13. 380-7.587 1.583 1.00 0.00 ATOM 484 2HE HIS+ 149-13.333-7.309-0.927 1.00 0.00 ATOM 485 C HIS+ 149-7.524-4.567 0.780 1.00 0.00 ATOM 486 O HIS+ 149-6.751-5.290 0.156 1.00 0.00 ATOM 487 N TRP 150-7.276-3.280 1.026 1.00 0.00 ATOM 488 H TRP 150-7.924-2.758 1.546 1.00 0.00 ATOM 489 CA TRP 150-6.047-2.635 0.556 1.00 0.00 ATOM 490 HA TRP 150-6.008-2.718-0.521 1.00 0.00 ATOM 491 CB TRP 150-6.005-1.162 0.963 1.00 0.00 ATOM 492 1HB TRP 150-5. 028-0.765 0.728 1.00 0.00 ATOM 493 2HB TRP 150-6. 165-1.090 2.028 1.00 0.00 ATOM 494 QB TRP 150-5.597-0.927 1.378 1.00 0.00 ATOM 495 CG TRP 150-7. 025-0.296 0.292 1.00 0.00 ATOM 496 CD1 TRP 150-7.521 0.883 0.766 1.00 0.00 ATOM 497 CD2 TRP 150-7.667-0.523-0.966 1.00 0.00 ATOM 498 CE3 TRP 150-7.593-1.532-1.928 1.00 0.00 ATOM 499 CE2 TRP 150-8.536 0.559-1.188 1.00 0.00 ATOM 500 NE1 TRP 150-8.429 1.401-0.119 1.00 0.00 ATOM 501 HD TRP 150-7. 231 1.331 1.705 1.00 0.00 ATOM 502 3HE TRP 150-6. 942-2.381-1.799 1.00 0.00 ATOM 503 CZ3 TRP 150-8.376-1.432-3.055 1.00 0.00 ATOM 504 CZ2 TRP 150-9.322 0.660-2.327 1.00 0.00 ATOM 505 1HE TRP 150-8.924 2.241-0.006 1.00 0.00 ATOM 506 3HZ TRP 150-8.342-2.208-3.803 1.00 0.00 ATOM 507 CH2 TRP 150-9. 229-0.344-3.245 1.00 0.00 ATOM 508 2HZ TRP 150-9.991 1.495-2.493 1.00 0.00 ATOM 509 HH TRP 150-9. 826-0.311-4.144 1.00 0.00 ATOM 510 C TRP 150-4.837-3.336 1.128 1.00 0.00 ATOM 511 O TRP 150-3.818-3.457 0. 462 1.00 0.00 ATOM 512 N HIS+ 151-4.964-3.811 2.358 1.00 0.00 ATOM 513 H HIS+ 151-5.814-3.692 2.833 1.00 0.. 00 ATOM 514 CA HIS+ 151-3.881-4.527 3.006 1.00 0.00 ATOM 515 HA HIS+ 151-3.020-3.876 3.037 1.00 0.00 ATOM 516 CB HIS+ 151-4.283-4.918 4.436 1.00 0.00 ATOM 517 1HB HIS+ 151-5.124-5.595 4.387 1.00 0.00 ATOM 518 2HB HIS+ 151-4.578-4.029 4.972 1.00 0.00 ATOM 519 QB HIS+ 151-4.851-4.812 4.680 1.00 0.00 ATOM 520 CG HIS+ 151-3.198-5.590 5.227 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.863-5.219 6.511 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.384-6.627 4.915 1.00 0.00 ATOM 523 1HD HIS+ 151-3.276-4.492 7.025 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.891-5.998 6.952 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.583-6.862 6.004 1.00 0.00 ATOM 526 2HD HIS+ 151-2.365-7.160 3.970 1. 00 0. 00 ATOM 527 1HE HIS+ 151-1.418-5.932 7.922 1.00 0.00 ATOM 528 2HE HIS+ 151-1.004-7.644 6.124 1.00 0.00 ATOM 529 C HIS+ 151-3.542-5.765 2.188 1.00 0.00 ATOM 530 O HIS+ 151-2.375-6.047 1.925 1.00 0.00 ATOM 531 N THR 152-4.575-6.490 1.782 1. oo o. oo ATOM 532 H THR 152-5.482-6.204 2.019 1.00 0.00 ATOM 533 CA THR 152-4.400-7.690 0.985 l. oo o. oo ATOM 534 HA THR 152-3.682-8.318 1.491 1. 00 0. 00

ATOM 535 CB THR 152-5. 725-8.448 0.868 1.00 0.00 ATOM 536 HB THR 152-6.384-7.904 0.203 1.00 0.00 ATOM 537 QG2 THR 152-5.534-10.186 0.194 1.00 0.00 ATOM 538 OG1 THR 152-6.353-8.553 2.135 1.00 0.00 ATOM 539 1HG THR 152-6. 663-7.684 2.419 1.00 0.00 ATOM 540 CG2 THR 152-5.571-9.852 0.323 1.00 0.00 ATOM 541 1HG2 THR 152-5.574-10.558 1.141 1.00 0.00 ATOM 542 2HG2 THR 152-4.638-9.930-0.217 1.00 0.00 ATOM 543 3HG2 THR 152-6.391-10.072-0.344 1.00 0.00 ATOM 544 C THR 152-3.849-7.350-0.395 1.00 0.00 ATOM 545 0 THR 152-2. 889-7.963-0.833 1.00 0.00 ATOM 546 N VAL 153-4.441-6.360-1.065 1.00 0.00 ATOM 547 H VAL 153-5.199-5.883-0.654 1.00 0.00 ATOM 548 CA VAL 153-3.971-5.956-2.392 1.00 0.00 ATOM 549 HA VAL 153-4.042-6.811-3.043 1.00 0.00 ATOM 550 CB VAL 153-4.831-4.813-2.981 1.00 0.00 ATOM 551 HB VAL 153-4.681-3.929-2.378 1.00 0.00 ATOM 552 QG1 VAL 153-4.311-4.416-4.745 1.00 0.00 ATOM 553 QG2 VAL 153-6.659-5.258-2.927 1.00 0.00 ATOM 554 CG1 VAL 153-4.410-4.492-4.407 1.00 0.00 ATOM 555 1HG1 VAL 153-5.101-4.953-5.098 1.00 0.00 ATOM 556 2HG1 VAL 153-3.415-4.874-4.585 1.00 0.00 ATOM 557 3HG1 VAL 153-4.416-3.422-4.553 1.00 0.00 ATOM 558 CG2 VAL 153-6.308-5.174-2.937 1.00 0.00 ATOM 559 1HG2 VAL 153-6.883-4.400-3.426 1.00 0.00 ATOM 560 2HG2 VAL 153-6.628-5.263-1.909 1.00.0.00 ATOM 561 3HG2 VAL 153-6.465-6.113-3.446 1.00 0.00 ATOM 562 QQG VAL 153-5.485-4.837-3.836 1.00 0.00 ATOM 563 C VAL 153-2.516-5.524-2.328 1.00 0.00 ATOM 564 O VAL 153-1.686-5.976-3.117 1.00 0.00 ATOM 565 N ALA 154-2.215-4.665-1.370 1.00 0.00 ATOM 566 H ALA 154-2.933-4.355-0.766 1.00 0.00 ATOM 567 CA ALA 154-0.860-4.178-1.170 1.00 0.00 ATOM 568 HA ALA 154-0.542-3.666-2.066 1.00 0.00 ATOM 569 QB ALA 154-0.830-2.961 0.259 1.00 0.00 ATOM 570 CB ALA 154-0.836-3.195-0.015 1.00 0.00 ATOM 571 1HB ALA 154-0.245-2.333-0.290 1.00 0.00 ATOM 572 2HB ALA 154-0.400-3.669 0.852 1.00 0.00 ATOM 573 3HB ALA 154-1.844-2.882 0.214 1.00 0.00 ATOM 574 C ALA 154 0.097-5.327-0.893 1.00 0.00 ATOM 575 O ALA 154 1.125-5.469-1.557 1.00 0.00 ATOM 576 N LYS+ 155-0.251-6.145 0.095 1.00 0.00 ATOM 577 H LYS+ 155-1.086-5.973 0.585 1.00 0.00 ATOM 578 CA LYS+ 155 0.570-7.286 0.470 1.00 0.00 ATOM 579 HA LYS+ 155 1.541-6.914 0.779 1.00 0.00 ATOM 580 CB LYS+ 155-0.074-8.055 1.630 1.00 0.00 ATOM 581 1HB LYS+ 155-0.728-8.812 1.221 1.00 0.00 ATOM 582 2HB LYS+ 155-0.665-7.365 2.216 1. 00 0.00 ATOM 583 QB LYS+ 155-0.697-8. 088 1.719 1.00 0.00 ATOM 584 CG LYS+ 155 0.922-8.739 2.564 1.00 0.00 ATOM 585 1HG LYS+ 155 0.449-8.889 3.524 1.00 0.00 ATOM 586 2HG LYS+ 155 1.781-8.097 2.686 1.00 0.00 ATOM 587 QG LYS+ 155 1.115-8.493 3.105 1.00 0.00 ATOM 588 CD LYS+ 155 1.391-10.088 2.028 1.00 0.00 ATOM 589 1HD LYS+ 155 2.067-10. 532 2.746 1.00 0.00 ATOM 590 2HD LYS+ 155 1.911-9.930 1.094 1.00 0.00 ATOM 591 QD LYS+ 155 1.989-10.231 1.920 1.00 0.00 ATOM 592 CE LYS+ 155 0.230-11.046 1.785 1.00 0.00 ATOM 593 1HE LYS+ 155-0.653-10.658 2.272 1.00 0.00 ATOM 594 2HE LYS+ 155 0.478-12.010 2.207 1.00 0.00 ATOM 595 QE LYS+ 155-0.088-11.334 2.240 1.00 0.00 ATOM 596 NZ LYS+ 155-0.049-11.211 0.338 1.00 0.00 ATOM 597 1HZ LYS+ 155 0.797-11.563-0.164 1.00 0.00 ATOM 598 2HZ LYS+ 155-0.327-10.305-0.085 1.00 0.00 ATOM 599 3HZ LYS+ 155-0.834-11.894 0.185 1.00 0.00 ATOM 600 QZ LYS+ 155-0.121-11.254-0.021 1.00 0.00 ATOM 601 C LYS+ 155 0.763-8.207-0.719 1.00 0.00 ATOM 602 O LYS+ 155 1.894-8.558-1.034 1.00 0.00 ATOM 603 N GLU 156-0.342-8.592-1.368 1.00 0.00 ATOM 604 H GLU 156-1.221-8.269-1.055 1.00 0.00 ATOM 605 CA GLU 156-0.291-9.480-2.528 1.00 0.00 ATOM 606 HA GLU 156 0.030-10.452-2.182 1.00 0.00

ATOM 607 CB GLU 156-1.671-9.626-3.178 1.00 0.00 ATOM 608 1HB GLU 156-1.542-10.046-4.165 1.00 0.00 ATOM 609 2HB GLU 156-2. 116-8.647-3.272 1.00 0.00 ATOM 610 QB GLU 156-1.829-9.346-3.718 1.00 0.00 ATOM 611 CG GLU 156-2.643-10.515-2.408 1.00 0.00 ATOM 612 1HG GLU 156-3.389-10.882-3.096 1.00 0.00 ATOM 613 2HG GLU 156-3. 125-9.920-1.647 1.00 0.00 ATOM 614 QG GLU 156-3.257-10.401-2.371 1.00 0.00 ATOM 615 CD GLU 156-1.982-11.700-1.737 1.00 0.00 ATOM 616 OE1 GLU 156-2.374-12.029-0.598 1.00 0.00 ATOM 617 OE2 GLU 156-1.050-12.282-2.324 1.00 0.00 ATOM 618 C GLU 156 0.709-8.984-3.561 1.00 0.00 ATOM 619 O GLU 156 1.593-9.726-3.957 1.00 0.00 ATOM 620 N THR 157 0.566-7.731-3.987 1.00 0.00 ATOM 621 H THR 157-0.168-7.185-3.627 1.00 0.00 ATOM 622 CA THR 157 1.473-7.146-4.981 1.00 0.00 ATOM 623 HA THR 157 1.312-7.670-5.913 1.00 0.00 ATOM 624 CB THR 157 1.148-5.662-5.186 1.00 0.00 ATOM 625 HB THR 157 1.495-5.105-4.326 1.00 0.00 ATOM 626 QG2 THR 157 1.955-4.926-6.709 1.00 0.00 ATOM 627 OG1 THR 157-0. 249-5.465-5.313 1.00 0.00 ATOM 628 1HG THR 157-0.682-5.644-4.467 1.00 0.00 ATOM 629 CG2 THR 157 1.800-5.067-6.417 1.00 0.00 ATOM 630 1HG2 THR 157 1.320-4.131-6.662 1.00 0.00 ATOM 631 2HG2 THR 157 1.697-5.753-7.246 1.00 0.00 ATOM 632 3HG2 THR 157 2.848-4.894-6.221 1.00 0.00 ATOM 633 C THR 157 2.945-7.314-4.580 1.00 0.00 ATOM 634 O THR 157 3.806-7.579-5.425 1.00 0.00 ATOM 635 N CYS 158 3.238-7.154-3.295 1.00 0.00 ATOM 636 H CYS 158 2.517-6.932-2.659 1.00 0.00 ATOM 637 CA CYS 158 4.608-7.290-2.813 1.00 0.00 ATOM 638 HA CYS 158 5.255-6.832-3.547 1.00 0.00 ATOM 639 CB CYS 158 4.776-6.543-1.493 1.00 0.00 ATOM 640 1HB CYS 158 5.658-6.897-0.994 1.00 0.00 ATOM 641 2HB CYS 158 3.919-6.738-0.871 1.00 0.00 ATOM 642 QB CYS 158 4.788-6.817-0.932 1.00 0.00 ATOM 643 SG CYS 158 4.925-4.730-1.694 1.00 0.00 ATOM 644 C CYS 158 5.019-8.762-2.669 1.00 0.00 ATOM 645 O CYS 158 6.109-9.138-3.100 1.00 0.00 ATOM 646 N SER 159 4.158-9.592-2.066 1.00 0.00 ATOM 647 H SER 159 3.304-9.242-1.734 1.00 0.00 ATOM 648 CA SER 159 4.466-11.016-1.880 1.00 0.00 ATOM 649 HA SER 159 5.456-11.077-1.449 1.00 0.00 ATOM 650 CB SER 159 3.476-11.680-0.923 1.00 0.00 ATOM 651 1HB SER 159 3.725-11.408 0.093 1.00 0.00 ATOM 652 2HB SER 159 3.542-12.754-1.033 1.00 0.00 ATOM 653 QB SER 159 3.633-12.081-0.470 1.00 0.00 ATOM 654 OG SER 159 2.146-11.277-1.193 1.00 0.00 ATOM 655 HG SER 159 1.961-11.385-2.138 1.00 0.00 ATOM 656 C SER 159 4.478-11.771-3.208 1.00 0.00 ATOM 657 O SER 159 5.149-12.792-3.331 1.00 0.00 ATOM 658 N GLU 160 3.745-11.254-4.196 1.00 0.00 ATOM 659 H GLU 160 3.236-10.431-4.032 1.00 0.00 ATOM 660 CA GLU 160 3.692-11.864-5.523 1.00 0.00 ATOM 661 HA GLU 160 3.379-12.893-5.416 1.00 0.00 ATOM 662 CB GLU 160 2.694-11.105-6.415 1.00 0.00 ATOM 663 1HB GLU 160 2.853-10.044-6.284 1.00 0.00 ATOM 664 2HB GLU 160 1.691-11.345-6.099 1.00 0.00 ATOM 665 QB GLU 160 2.272-10.694-6.191 1.00 0.00 ATOM 666 CG GLU 160 2.808-11.416-7.900 1.00 0.00 ATOM 667 1HG GLU 160 1.827-11.652-8.285 1.00 0.00 ATOM 668 2HG GLU 160 3.461-12.267-8.029 1.00 0.00 ATOM 669 QG GLU 160 2.644-11.959-8.157 1.00 0.00 ATOM 670 CD GLU 160 3.371-10.253-8.686 1.00 0.00 ATOM 671 OE1 GLU 160 4.441-10.414-9.308 1.00 0.00 ATOM 672 OE2 GLU 160 2.767-9.163-8.657 1.00 0.00 ATOM 673 C GLU 160 5.088-11.820-6.124 1.00 0.00 ATOM 674 O GLU 160 5.497-12.693-6.889 1.00 0.00 ATOM 675 N LYS+ 161 5.819-10.792-5.724 1. 00 0. 00 ATOM 676 H LYS+ 161 5.430-10.157-5.091 1.00 0.00 ATOM 677 CA LYS+ 161 7.178-10.594-6. 158 1.00 0.00 ATOM 678 HA LYS+ 161 7.315-11.103-7.101 1.00 0.00

ATOM 679 CB LYS+ 161 7.450-9.095-6.327 1.00 0.00 ATOM 680 1HB LYS+ 161 7.868-8.714-5.406 1.00 0.00 ATOM 681 2HB LYS+ 161 6.515-8.593-6.519 1.00 0.00 ATOM 682 QB LYS+ 161 7.191-8.653-5.962 1.00 0.00 ATOM 683 CG LYS+ 161 8.411-8.764-7.458 1.00 0.00 ATOM 684 1HG LYS+ 161 9.233-9.466-7.437 1.00 0.00 ATOM 685 2HG LYS+ 161 8.788-7.762-7.319 1.00 0.00 ATOM 686 QG LYS+ 161 9.010-8.614-7.378 1.00 0.00 ATOM 687 CD LYS+ 161 7.721-8.850-8.815 1.00 0.00 ATOM 688 1HD LYS+ 161 7.192-9.791-8.880 1.00 0.00 ATOM 689 2HD LYS+ 161 8.471-8.806-9.592 1.00 0.00 ATOM 690 QD LYS+ 161 7.831-9.298-9.236 1.00 0.00 ATOM 691 CE LYS+ 161 6.730-7.709-9.023 1.00 0.00 ATOM 692 1HE LYS+ 161 6. 684-7.481-10.079 1.00 0.00 ATOM 693 2HE LYS+ 161 7.082-6.842-8.485 1.00 0.00 ATOM 694 QE LYS+ 161 6.883-7.161-9.282 1.00 0.00 ATOM 695 NZ LYS+ 161 5.363-8.055-8.543 1.00 0.00 ATOM 696 1HZ LYS+ 161 5.110-9.036-8.833 1.00 0.00 ATOM 697 2HZ LYS+ 161 4.657-7.410-8.950 1.00 0.00 ATOM 698 3HZ LYS+ 161 5.309-7.996-7.508 1.00 0.00 ATOM 699 QZ LYS+ 161 5.025-8.147-8.430 1.00 0.00 ATOM 700 C LYS+ 161 8.104-11.200-5.109 1.00 0.00 ATOM 701 O LYS+ 161 7.836-12.277-4.585 1.00 0.00 ATOM 702 N SER 162 9.179-10.511-4.790 1.00 0.00 ATOM 703 H SER 162 9.348-9.656-5.223 1.00 0.00 ATOM 704 CA SER 162 10.109-11.002-3.791 1.00 0.00 ATOM 705 HA SER 162 9.746-11.957-3.446 1.00 0.00 ATOM 706 CB SER 162 11.494-11.191-4.410 1.00 0.00 ATOM 707 1HB SER 162 11.885-12.156-4.119 1.00 0.00 ATOM 708 2HB SER 162 12.153-10.414-4.050 1.00 0.00 ATOM 709 QB SER 162 12.019-11.285-4.084 1.00 0.00 ATOM 710 OG SER 162 11.432-11.126-5.830 1.00 0.00 ATOM 711 HG SER 162 11.350-12.015-6.185 1.00 0.00 ATOM 712 C SER 162 10.188-10.047-2.605 1.00 0.00 ATOM 713 0 SER 162 11.277-9.651-2.199 1.00 0.00 ATOM 714 N THR 163 9.037-9.659-2.052 1.00 0.00 ATOM 715 H THR 163 8.185-9.991-2.414 1.00 0.00 ATOM 716 CA THR 163 9.024-8.748-0.911 1.00 0.00 ATOM 717 HA THR 163 9.952-8.883-0.372 1.00 0.00 ATOM 718 CB THR 163 8.931-7.290-1.364 1.00 0.00 ATOM 719 HB THR 163 8.821-6.673-0.479 1.00 0.00 ATOM 720 QG2 THR 163 10.429-6.673-2.307 1.00 0.00 ATOM 721 OG1 THR 163 7.801-7.096-2.192 1.00 0.00 ATOM 722 1HG THR 163 7.564-7.932-2.618 1.00 0.00 ATOM 723 CG2 THR 163 10.140-6.792-2.126 1.00 0.00 ATOM 724 1HG2 THR 163 10.665-6.059-1.531 1.00 0.00 ATOM 725 2HG2 THR 163 9.821-6.340-3.054 1.00 0.00 ATOM 726 3HG2 THR 163 10.800-7.622-2.337 1.00 0.00 ATOM 727 C THR 163 7.863-9.043 0.039 1.00 0.00 ATOM 728 O THR 163 6. 891-9.705-0.321 1.00 0.00 ATOM 729 N ASN 164 7.969-8.518 1.251 1.00 0.00 ATOM 730 H ASN 164 8.770-7.990 1.465 1.00 0.00 ATOM 731 CA ASN 164 6.930-8.688 2.272 1.00 0.00 ATOM 732 HA ASN 164 6.075-9.157 1.798 1.00 0.00 ATOM 733 CB ASN 164 7.428-9.581 3.419 1.00 0.00 ATOM 734 1HB ASN 164 7.248-10.616 3.163 1.00 0.00 ATOM 735 2HB ASN 164 6.881-9.340 4.318 1.00 0.00 ATOM 736 QB ASN 164 7.064-9.978 3.741 1.00 0.00 ATOM 737 CG ASN 164 8.912-9.411 3.705 1.00 0.00 ATOM 738 OD1 ASN 164 9.594-10.361 4.065 1.00 0.00 ATOM 739 ND2 ASN 164 9.411-8.190 3.567 1.00 0.00 ATOM 740 1HD2 ASN 164 8.799-7.470 3.310 1.00 0.00 ATOM 741 2HD2 ASN 164 10.372-8.068 3.680 1.00 0.00 ATOM 742 QD2 ASN 164 9.585-7.769 3.495 1.00 0.00 ATOM 743 C ASN 164 6.507-7.330 2.834 1.00 0.00 ATOM 744 O ASN 164 7.357-6.500 3.153 1.00 0.00 ATOM 745 N LEU 165 5.203-7.101 2.950 1.00 0.00 ATOM 746 H LEU 165 4.572-7.795 2.679 1.00 0.00 ATOM 747 CA LEU 165 4.688-5.830 3.473 1.00 0.00 ATOM 748 HA LEU 165 5.154-5.022 2.927 1.00 0.00 ATOM 749 CB LEU 165 3.172-5.738 3.302 1.00 0.00 ATOM 750 1HB LEU 165 2.730-5.584 4.275 1.00 0.00

ATOM 751 2HB LEU 165 2.813-6.675 2.902 1.00 0.00 ATOM 752 QB LEU 165 2.771-6.129 3.589 1.00 0.00 ATOM 753 CG LEU 165 2.698-4.616 2.398 1.00 0.00 ATOM 754 HG LEU 165 3.215-3.704 2.660 1.00 0.00 ATOM 755 QD1 LEU 165 3.092-5.017 0.616 1.00 0.00 ATOM 756 QD2 LEU 165 0.855-4.331 2.625 1.00 0.00 ATOM 757 CD1 LEU 165 3.016-4.941 0.960 1.00 0.00 ATOM 758 1HD1 LEU 165 2.150-4.740 0.344 1.00 0.00 ATOM 759 2HD1 LEU 165 3.283-5.983 0.876 1.00 0.00 ATOM 760 3HD1 LEU 165 3.842-4.330 0.626 1.00 0.00 ATOM 761 CD2 LEU 165 1.208-4.386 2.582 1.00 0.00 ATOM 762 1HD2 LEU 165 0.987-4.272 3.633 1.00 0.00 ATOM 763 2HD2 LEU 165 0.662-5.231 2.188 1.00 0.00 ATOM 764 3HD2 LEU 165 0.915-3.491 2.053 1.00 0.00 ATOM 765 QQD LEU 165 1.973-4.674 1.620 1.00 0.00 ATOM 766 C LEU 165 5.018-5.663 4.943 1.00 0.00 ATOM 767 O LEU 165 4.685-6.515 5.764 1.00 0.00 ATOM 768 N HIS+ 166 5.656-4.554 5.261 1.00 0.00 ATOM 769 H HIS+ 166 5.883-3. 911 4.556 1.00 0.00 ATOM 770 CA HIS+ 166 6.020-4.250 6.629 1.00 0.00 ATOM 771 HA HIS+ 166 5.725-5.086 7.246 1.00 0.00 ATOM 772 CB HIS+ 166 7.538-4.054 6.739 1.00 0.00 ATOM 773 1HB HIS+ 166 7.828 J3.215 6. 120 1.00 0.00 ATOM 774 2HB HIS+ 166 8.035-4.943 6.384 1.00 0.00 ATOM 775 QB HIS+ 166 7.931-4.079 6.252 1.00 0.00 ATOM 776 CG HIS+ 166 8.019-3.785 8.130 1.00 0.00 ATOM 777 ND1 HIS+ 166 8.036-4.738 9.126 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.493-2.651 8.689 1.00 0.00 ATOM 779 1HD HIS+ 166 7.747-5.670 9.032 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.501-4.196 10.239 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.786-2.927 9.999 1.00 0.00 ATOM 782 2HD HIS+ 166 8.603-1.691 8.193 1.00 0.00 ATOM 783 1HE HIS+ 166 8.626-4.703 11.184 1.00 0.00 ATOM 784 2HE HIS+ 166 8.945-2.248 10.688 1.00 0.00 ATOM 785 C HIS+ 166 5.279-3.001 7.102 1.00 0.00 ATOM 786 0 HIS+ 166 4.638-3.011 8.154 1.00 0.00 ATOM 787 N ASP 167 5.364-1.931 6.314 1.00 0.00 ATOM 788 H ASP 167 5.886-1.989 5.483 1.00 0.00 ATOM 789 CA ASP 167 4.700-0.671 6.660 1.00 0.00 ATOM 790 HA ASP 167 4.209-0.814 7.612 1.00 0.00 ATOM 791 CB ASP 167 5.712 0.475 6.797 1.00 0.00 ATOM 792 1HB ASP 167 5.317 1.209 7.484 1.00 0.00 ATOM 793 2HB ASP 167 5.851 0.936 5.832 1.00 0.00 ATOM 794 QB ASP 167 5.584 1.073 6.658 1.00 0.00 ATOM 795 CG ASP 167 7.067 0.027 7.307 1.00 0.00 ATOM 796 OD1 ASP 167 7.889-0.439 6.486 1.00 0.00 ATOM 797 OD2 ASP 167 7.311 0.147 8.525 1. 00 0.00 ATOM 798 C ASP 167 3.648-0.292 5.620 1.00 0.00 ATOM 799 O ASP 167 3.931 0.426 4.665 1.00 0.00 ATOM 800 N TYR 168 2.437-0.787 5.810 1.00 0.00 ATOM 801 H TYR 168 2.277-1.355 6.592 1.00 0.00 ATOM 802 CA TYR 168 1.325-0. 506 4.900 1.00 0.00 ATOM 803 HA TYR 168 1.734-0.281 3.918 1.00 0.00 ATOM 804 CB TYR 168 0.418-1.734 4.801 1.00 0.00 ATOM 805 1HB TYR 168 0.771-2.372 4.004 1.00 0. 00 ATOM 806 2HB TYR 168-0.589-1.414 4.582 1.00 0. 00 ATOM 807 QB TYR 168 0.091-1.893 4.293 1.00 0.00 ATOM 808 QD TYR 168 0.380-2.642 6.224 1.00 0.00 ATOM 809 QE TYR 168 0.334-3.945 8.305 1.00 0.00 ATOM 810 QR TYR 168 0.357-3.293 7.264 1.00 0.00 ATOM 811 CG TYR 168 0.382-2.551 6.075 1.00 0.00 ATOM 812 CD1 TYR 168-0.469-2.204 7.116 1. 00 0. 00 ATOM 813 1HD TYR 168-1.115-1.346 7.002 1.00 0.00 ATOM 814 CE1 TYR 168-0.497-2.932 8.287 1.00 0.00 ATOM 815 1HE TYR 168-1.166-2.644 9.085 1.00 0.00 ATOM 816 CZ TYR 168 0.331-4.024 8.430 1.00 0.00 ATOM 817 CE2 TYR 168 1.184-4.391 7.412 1.00 0.00 ATOM 818 2HE TYR 168 1.834-5.246 7.525 1.00 0. 00 ATOM 819 CD2 TYR 168 1.208-3.656 6.244 1.00 0.00 ATOM 820 2HD TYR 168 1.876-3.939 5.445 1.00 0.00 ATOM 821 OH TYR 168 0.304-4.754 9. 594 1.00 0.00 ATOM 822 HH TYR 168 1.046-4.499 10.150 1.00 0.00

ATOM 823 C TYR 168 0.512 0.694 5.380 1.00 0.00 ATOM 824 O TYR 168 0.360 0.915 6.581 1.00 0.00 ATOM 825 N GLY 169-0.029 1.442 4.435 1.00 0.00 ATOM 826 H GLY 169 0.111 1.205 3.493 1.00 0.00 ATOM 827 CA GLY 169-0.839 2.594 4.760 1.00 0.00 ATOM 828 1HA GLY 169-0.226 3.483 4.723 1.00 0.00 ATOM 829 2HA GLY 169-1.240 2.477 5.756 1.00 0.00 ATOM 830 QA GLY 169-0.733 2.980 5.240 1.00 0.00 ATOM 831 C GLY 169-1.971 2.734 3.775 1.00 0.00 ATOM 832 O GLY 169-1.896 2.195 2.672 1.00 0.00 ATOM 833 N MET 170-3.021 3.435 4.158 1.00 0.00 ATOM 834 H MET 170-3.032 3.837 5.052 1.00 0.00 ATOM 835 CA MET 170-4.165 3.619 3.277 1.00 0.00 ATOM 836 HA MET 170-3.835 3.421 2.259 1.00 0.00 ATOM 837 CB MET 170-5.287 2.644 3.645 1.00 0.00 ATOM 838 1HB MET 170-6.200 2.970 3.168 1.00 0.00 ATOM 839 2HB MET 170-5.426 2.659 4.715 1.00 0.00 ATOM 840 QB MET 170-5.813 2.815 3.942 1.00 0.00 ATOM 841 CG MET 170-5.011 1.211 3.218 1.00 0.00 ATOM 842 1HG MET 170-4.343 1. 227 2.368 1.00 0.00 ATOM 843 2HG MET 170-5.944 0.749 2.931 1.00 0.00 ATOM 844 QG MET 170-5.144 0.988 2.650 1.00 0.00 ATOM 845 SD MET 170-4.257 0.224 4.525 1.00 0. 00 ATOM 846 QE MET 170-3.013-1.106 3.384 1.00 0.00 ATOM 847 CE MET 170-3.221-0.884 3.575 1.00 0.00 ATOM 848 1HE MET 170-2.422-1.253 4.199 1.00 0.00 ATOM 849 2HE MET 170-2.803-0.352 2.732 1.00 0.00 ATOM 850 3HE MET 170-3.814-1.715 3.219 1.00 0.00 ATOM 851 C MET 170-4.665 5.053 3.364 1.00 0.00 ATOM 852 O MET 170-5.154 5.489 4.407 1.00 0.00 ATOM 853 N LEU 171-4.525 5.785 2.271 1.00 0.00 ATOM 854 H LEU 171-4.119 5.381 1.476 1.00 0.00 ATOM 855 CA LEU 171-4.944 7.177 2.227 1.00 0.00 ATOM 856 HA LEU 171-5.201 7.473 3.233 1.00 0.00 ATOM 857 CB LEU 171-3.796 8.058 1.731 1.00 0.00 ATOM 858 1HB LEU 171-3.854 9.009 2.238 1.00 0.00 ATOM 859 2HB LEU 171-3.929 8.226 0.670 1.00 0.00 ATOM 860 QB LEU 171-3.892 8.618 1.454 1.00 0.00 ATOM 861 CG LEU 171-2.398 7.483 1.954 1.00 0.00 ATOM 862 HG LEU 171-2.465 6.638 2.625 1.00 0.00 ATOM 863 QD1 LEU 171-1.667 6.879 0.333 1.00 0.00 ATOM 864 QD2 LEU 171-1.278 8.767 2.746 1.00 0.00 ATOM 865 CD1 LEU 171-1.808 6.994 0.643 1.00 0.00 ATOM 866 1HD1 LEU 171-0.729 7.028 0.701 1.00 0.00 ATOM 867 2HD1 LEU 171-2.145 7.630-0.164 1.00 0.00 ATOM 868 3HD1 LEU 171-2.126 5.979 0.460 1.00 0.00 ATOM 869 CD2 LEU 171-1.494 8.521 2.595 1.00 0. 00 ATOM 870 1HD2 LEU 171-0.581 8.046 2.927 1.00 0.00 ATOM 871 2HD2 LEU 171-1.996 8. 966 3.440 1.00.0.00 ATOM 872 3HD2 LEU 171-1.257 9.287 1.871 1.00 0.00 ATOM 873 QQD LEU 171-1.472 7.823 1.539 1.00 0. 00 ATOM 874 C LEU 171-6. 164 7.366 1.335 1.00 0.00 ATOM 875 O LEU 171-6.879 6.407 1.039 1. 00 0. 00 ATOM 876 N LEU 172-6.384 8.618 0.919 1. 00 0. 00 ATOM 877 H LEU 172-5.761 9.318 1.204 1.00 0.00 ATOM 878 CA LEU 172-7.513 8.996 0.061 1. 00 0. 00 ATOM 879 HA LEU 172-7.614 10.070 0.114 1.00 0.00 ATOM 880 CB LEU 172-7.243 8.604-1.395 1.00 0.00 ATOM 881 1HB LEU 172-8.075 8.008-1.740 1.00 0.00 ATOM 882 2HB LEU 172-6.351 7.994-1.424 1.00 0.00 ATOM 883 QB LEU 172-7.213 8.001-1.582 1. 00 0. 00 ATOM 884 CG LEU 172-7.058 9.775-2.363 1.00 0.00 ATOM 885 HG LEU 172-6.166 10.321-2.092 1.00 0.00 ATOM 886 QD1 LEU 172-6.839 9.146-4.119 1.00 0.00 ATOM 887 QD2 LEU 172-8.519 10.957-2.272 1. 00 0. 00 ATOM 888 CD1 LEU 172-6.882 9.266-3.782 1. 00 0. 00 ATOM 889 1HD1 LEU 172-5.833 9.285-4.043 1.00 0.00 ATOM 890 2HD1 LEU 172-7.432 9.899-4.463 1. 00 0. 00 ATOM 891 3HD1 LEU 172-7.252 8.254-3.852 1.00 0.00 ATOM 892 CD2 LEU 172-8.240 10.730-2.289 1.00 0.00 ATOM 893 1HD2 LEU 172-8.584 10.953-3.289 1.00 0.00 ATOM 894 2HD2 LEU 172-7.933 11.644-1.802 1.00 0. 00

ATOM 895 3HD2 LEU 172-9.039 10.272-1.727 1.00 0.00 ATOM 896 QQD LEU 172-7.679 10.052-3.196 1.00 0.00 ATOM 897 C LEU 172-8.825 8.365 0.530 1.00 0.00 ATOM 898 O LEU 172-9. 442 7.596-0.204 1.00 0.00 ATOM 899 N PRO 173-9.282 8.677 1.757 1.00 0.00 ATOM 900 CD PRO 173-8.640 9.587 2.718 1.00 0.00 ATOM 901 CA PRO 173-10.527 8.120 2.288 1.00 0.00 ATOM 902 HA'PRO 173-10.507 7.040 2.285 1.00 0.00 ATOM 903 CB PRO 173-10.579 8.633 3.735 1.00 0.00 ATOM 904 1HB PRO 173-10.858 7.823 4.394 1.00 0.00 ATOM 905 2HB PRO 173-11.308 9.428 3.808 1.00 0.00 ATOM 906 QB PRO 173-11.083 8.626 4.101 1.00 0.00 ATOM 907 CG PRO 173-9.202 9.127 4.031 1.00 0.00 ATOM 908 1HG PRO 173-8.602 8.324 4.435 1.00 0.00 ATOM 909 2HG PRO 173-9.249 9.950 4.730 1.00 0.00 ATOM 910 QG PRO 173-8.926 9.137 4.583 1.00 0.00 ATOM 911 1HD PRO 173-7.567 9.473 2.702 1.00 0.00 ATOM 912 2HD PRO 173-8.918 10.614 2.525 1.00 0.00 ATOM 913 QD PRO 173-8.243 10.044 2.614 1.00 0.00 ATOM 914 C PRO 173-11.746 8.605 1.510 1.00 0.00 ATOM 915 O PRO 173-11.892 9.798 1.242 1.00 0.00 ATOM 916 N CYS 174-12.619 7.678 1.152 1.00 0.00 ATOM 917 H CYS 174-12.453 6.741 1.396 1.00 0.00 ATOM 918 CA CYS 174-13.826 8.021 0.414 1.00 0.00 ATOM 919 HA CYS 174-13.808 9.087 0.235 1.00 0.00 ATOM 920 CB CYS 174-13. 876 7.291-0.925 1.00 0.00 ATOM 921 1HB CYS 174-13.211 7.784-1.619 1.00 0.00 ATOM 922 2HB CYS 174-14.884 7.334-1.310 1.00 0.00 ATOM 923 QB CYS 174-14.048 7.559-1.464 1.00 0.00 ATOM 924 SG CYS 174-13.392 5.538-0.843 1.00 0.00 ATOM 925 C CYS 174-15.060 7.688 1.236 1.00 0.00 ATOM 926 O CYS 174-16.113 8.301 1.075 1.00 0.00 ATOM 927 N GLY 175-14.915 6.721 2.128 1.00 0.00 ATOM 928 H GLY 175-14.044 6.276 2.220 1.00 0.00 ATOM 929 CA GLY 175-16.012 6.326 2.985 1.00 0.00 ATOM 930 1HA GLY 175-16.389 5.369 2.662 1.00 0.00 ATOM 931 2HA GLY 175-16.800 7.063 2.915 1.00 0.00 ATOM 932 QA GLY 175-16.595 6.216 2.789 1.00 0.00 ATOM 933 C GLY 175-15.558 6.221 4.419 1.00 0.00 ATOM 934 O GLY 175-14.386 6.453 4.705 1.00 0.00 ATOM 935 N ILE 176-16.473 5.866 5.318 1.00 0.00 ATOM 936 H ILE 176-17.390 5.691 5.025 1.00 0.00 ATOM 937 CA ILE 176-16.138 5.724 6.734 1.00 0.00 ATOM 938 HA ILE 176-15.846 6.695 7.108 1.00 0.00 ATOM 939 CB ILE 176-17.344 5.219 7.559 1.00 0.00 ATOM 940 HB ILE 176-17.280 4.143 7.620 1.00 0.00 ATOM 941 QG2 ILE 176-17.276 5.909 9.310 1.00 0.00 ATOM 942 CG2 ILE 176-17.289 5.777 8.975 1.00 0.00 ATOM 943 1HG2 ILE 176-16.277 6.076 9.206 1.00 0.00 ATOM 944 2HG2 ILE 176-17.608 5. 017 9.673 1.00 0.00 ATOM 945 3HG2 ILE 176-17.944 6.632 9.050 1.00 0.00 ATOM 946 CG1 ILE 176-18.665 5.605 6.884 1.00 0.00 ATOM 947 1HG1 ILE 176-18.741 5.093 5.937 1.00 0.00 ATOM 948 2HG1 ILE 176-18.676 6.672 6.714 1.00 0.00 ATOM 949 QG1 ILE 176-18.709 5.883 6. 326 1.00 0.00 ATOM 950 QD1 ILE 176-20.181 5.173 7.897 1.00 0.00 ATOM 951 CD1 ILE 176-19.889 5.256 7.702 1.00 0.00 ATOM 952 1HD1 ILE 176-19.641 5.288 8.753 1.00 0.00 ATOM 953 2HD1 ILE 176-20.226 4.263 7.442 1.00 0.00 ATOM 954 3HD1 ILE 176-20.675 5.968 7.496 1.00 0.00 ATOM 955 C ILE 176-14.968 4.754 6.905 1.00 0.00 ATOM 956 O ILE 176-13.983 5.062 7.572 1.00 0.00 ATOM 957 N ASP 177-15.081 3.597 6.260 1.00 0.00 ATOM 958 H ASP 177-15.882 3.431 5.727 1.00 0.00 ATOM 959 CA ASP 177-14.033 2.583 6.293 1.00 0.00 ATOM 960 HA ASP 177-13.163 3.016 6.770 1.00 0.00 ATOM 961 CB ASP 177-14.479 1.349 7.085 1.00 0.00 ATOM 962 1HB ASP 177-15.169 0.775 6.486 1.00 0.00 ATOM 963 2HB ASP 177-14.974 1.670 7.989 1.00 0.00 ATOM 964 QB ASP 177-15.072 1.223 7.238 1.00 0.00 ATOM 965 CG ASP 177-13.317 0.449 7.473 1.00 0.00 ATOM 966 OD1 ASP 177-13.553-0.536 8.198 1. 00 0. 00

ATOM 967 OD2 ASP 177-12.175 0.714 7.035 1.00 0.00 ATOM 968 C ASP 177-13.668 2.190 4.866 1.00 0.00 ATOM 969 O ASP 177-13.514 1.011 4.535 1.00 0.00 ATOM 970 N LYS+ 178-13.544 3.188 4.008 1.00 0.00 ATOM 971 H LYS+ 178-13.682 4.108 4.322 1.00 0.00 ATOM 972 CA LYS+ 178-13.197 2.957 2.613 1.00 0.00 ATOM 973 HA LYS+ 178-12.752 1.975 2.543 1.00 0.00 ATOM 974 CB LYS+ 178-14.424 3.023 1.700 1.00 0.00 ATOM 975 1HB LYS+ 178-14.162 2.599 0.741 1.00 0.00 ATOM 976 2HB LYS+ 178-14.689 4.058 1.561 1.00 0.00 ATOM 977 QB LYS+ 178-14.426 3.329 1.151 1.00 0.00 ATOM 978 CG LYS+ 178-15.642 2.278 2.242 1.00 0.00 ATOM 979 1HG LYS+ 178-16.456 2.979 2.355 1.00 0.00 ATOM 980 2HG LYS+ 178-15.394 1.857 3.205 1.00 0.00 ATOM 981 QG LYS+ 178-15.925 2.418 2.780 1.00 0.00 ATOM 982 CD LYS+ 178-16.084 1.155 1.312 1.00 0.00 ATOM 983 1HD LYS+ 178-15.887 1.451 0.290 1.00 0.00 ATOM 984 2HD LYS+ 178-17.144 0.993 1.440 1.00 0.00 ATOM 985 QD LYS+ 178-16.516 1.222 0.865 1.00 0.00 ATOM 986 CE LYS+ 178-15.351-0.153 1.594 1.00 0.00 ATOM 987 1HE LYS+ 178-14.366-0.097 1. 151 1. 00 0.00 ATOM 988 2HE LYS+ 178-15.902-0.960 1.135 1.00 0.00 ATOM 989 QE LYS+ 178-15.134-0.528 1.143 1.00 0.00 ATOM 990 NZ LYS+ 178-15.210-0.435 3.054 1.00 0.00 ATOM 991 1HZ LYS+ 178-14. 798-1.387 3.197 1.00 0.00 ATOM 992 2HZ LYS+ 178-16.135-0.399 3.523 1.00 0.00 ATOM 993 3HZ LYS+ 178-14.576 0.269 3.503 1.00 0.00 ATOM 994 QZ LYS+ 178-15.170-0.505 3.408 1.00 0.00 ATOM 995 C LYS+ 178-12.168 3.971 2.176 1.00 0.00 ATOM 996 O LYS+ 178-12.316 5.170 2.413 1.00 0.00 ATOM 997 N PHE 179-11. 119 3.481 1.555 1.00 0.00 ATOM 998 H PHE 179-11.062 2.516 1.405 1.00 0.00 ATOM 999 CA PHE 179-10.040 4.331 1.106 1.00 0.00 ATOM 1000 HA PHE 179-10.318 5.356 1.299 1.00 0.00 ATOM 1001 CB PHE 179-8.763 4.006 1.879 1.00 0.00 ATOM 1002 1HB PHE 179-8.051 4.783 1.701 1.00 0.00 ATOM 1003 2HB PHE 179-8.356 3.075 1.516 1.00 0.00 ATOM 1004 QB PHE 179-8. 204 3.929 1.609 1.00 0.00 ATOM 1005 QD PHE 179-8.987 3.872 3.531 1.00 0.00 ATOM 1006 QE PHE 179-9.336 3.687 5.959 1.00 0.00 ATOM 1007 QR PHE 179-9.231 3.743 5.231 1.00 0.00 ATOM 1008 CG PHE 179-8.963 3.886 3.365 1.00 0.00 ATOM 1009 CD1 PHE 179-8.783 4.983 4.190 1.00 0.00 ATOM 1010 1HD PHE 179-8.488 5.928 3.758 1.00 0.00 ATOM 1011 CE1 PHE 179-8.978 4.882 5.554 1.00 0.00 ATOM 1012 1HE PHE 179-8. 834 5.746 6.186 1.00 0.00 ATOM 1013 CZ PHE 179-9.356 3.675 6.109 1.00 0.00 ATOM 1014 HZ PHE 179-9.511 3.595 7.176 1.00 0.00 ATOM 1015 CE2 PHE 179-9.538 2.572 5.299 1.00 0.00 ATOM 1016 2HE PHE 179-9.837 1. 627 5.731 1.00 0.00 ATOM 1017 CD2 PHE 179-9.343 2.679 3.936 1.00 0.00 ATOM 1018 2HD PHE 179-9.486 1.815 3.303 1.00 0.00 ATOM 1019 C PHE 179-9.791 4.155-0.374 1.00 0.00 ATOM 1020 O PHE 179-10.461 3.365-1.036 1.00 0.00 ATOM 1021 N ARG+ 180-8.809 4.883-0.876 1.00 0.00 ATOM 1022 H ARG+ 180-8.311 5.484-0.280 1.00 0.00 ATOM 1023 CA ARG+ 180-8.437 4.813-2.278 1.00 0.00 ATOM 1024 HA ARG+ 180-8.867 3.915-2.699 1.00 0.00 ATOM 1025 CB ARG+ 180-8.974 6.030-3.037 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.781 5.890-4.091 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.447 6.910-2.700 1.00 0.00 ATOM 1028 QB ARG+ 180-8.614 6.400-3.395 1.00 0.00 ATOM 1029 CG ARG+ 180-10.462 6.262-2.850 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.608 6.945-2.025 1.00 0.00 ATOM 1031 2HG ARG+ 180-10.936 5.316-2.623 1.00 0.00 ATOM 1032 QG ARG+ 180-10.772 6.131-2.324 1.00 0.00 ATOM 1033 CD ARG+ 180-11.100 6.843-4.098 1.00 0.00 ATOM 1034 1HD ARG+ 180-11.939 6.221-4.377 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.370 6.838-4.895 1.00 0.00 ATOM 1036 QD ARG+ 180-11.155 6.530-4.636 1.00 0.00 ATOM 1037 NE ARG+ 180-11.568 8.210-3.887 1.00 0.00 ATOM 1038 HE ARG+ 180-11.279 8.664-3.064 1.00 0.00

ATOM 1039 CZ ARG+ 180-12.361 8.858-4.738 1.00 0.00 ATOM 1040 NH1 ARG+ 180-12.727 8.276-5.876 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.404 7.350-6.094 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.317 8.757-6.524 1.00 0.00 ATOM 1043 QH1 ARG+ 180-12.861 8. 054-6.309 1.00 0.00 ATOM 1044 NH2 ARG+ 180-12.764 10.094-4.462 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.473 10.540-3.613 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.358 10.585-5.102 1.00 0.00 ATOM 1047 QH2 ARG+ 180-12.916 10.563-4.357 1.00 0.00 ATOM 1048 C ARG+ 180-6.920 4.754-2.423 1.00 0.00 ATOM 1049 O ARG+ 180-6.400 4.337-3.451 1.00 0.00 ATOM 1050 N GLY 181-6.208 5.181-1.391 1.00 0.00 ATOM 1051 H GLY 181-6.665 5.506-0.585 1.00 0.00 ATOM 1052 CA GLY 181-4.761 5.180-1.452 1.00 0.00 ATOM 1053 1HA GLY 181-4.396 6.132-1.095 1.00 0.00 ATOM 1054 2HA GLY 181-4.460 5.057-2.482 1.00 0.00 ATOM 1055 QA GLY 181-4.428 5.595-1.788 1.00 0.00 ATOM 1056 C GLY 181-4. 134 4.079-0.631 1.00 0.00 ATOM 1057 O GLY 181-4.706 3.628 0.359 1.00 0.00 ATOM 1058 N VAL 182-2.949 3.652-1.046 1.00 0.00 ATOM 1059 H VAL 182-2.552 4.063-1.840 1.00 0.00 ATOM 1060 CA VAL 182-2.208 2.601-0.360 1.00 0.00 ATOM 1061 HA VAL 182-2.520 2.585 0.677 1.00 0.00 ATOM 1062 CB VAL 182-2.455 1.199-0.977 1.00 0.00 ATOM 1063 HB VAL 182-1.679 1.016-1.708 1.00 0.00 ATOM 1064 QG1 VAL 182-2.331-0.130 0.344 1.00 0.00 ATOM 1065 QG2 VAL 182-4.120 1.097-1.850 1.00 0.00 ATOM 1066 CG1 VAL 182-2.355 0.125 0.091 1.00 0.00 ATOM 1067 1HG1 VAL 182-2.281 0.589 1.064 1.00 0.00 ATOM 1068 2HG1 VAL 182-1.477-0.480-0.088 1.00 0.00 ATOM 1069 3HG1 VAL 182-3.235-0.500 0.056 1.00 0.00 ATOM 1070 CG2 VAL 182-3.802 1.116-1.684 1.00 0.00 ATOM 1071 1HG2 VAL 182-4.117 0.085-1.739 1.00 0.00 ATOM 1072 2HG2 VAL 182-3.710 1.519-2.682 1.00 0.00 ATOM 1073 3HG2 VAL 182-4.534 1. 687-1. 131 1.00 0.00 ATOM 1074 QQG VAL 182-3.226 0.484-0.753 1.00 0.00 ATOM 1075 C VAL 182-0.711 2.899-0.421 1.00 0.00 ATOM 1076 O VAL 182-0.160 3.119-1.499 1.00 0.00 ATOM 1077 N GLU 183-0.063 2.901 0.735 1.00 0.00 ATOM 1078 H GLU 183-0.563 2.716 1.564 1.00 0.00 ATOM 1079 CA GLU 183 1.372 3.165 0.818 1.00 0.00 ATOM 1080 HA GLU 183 1.777 3.143-0.185 1.00 0.00 ATOM 1081 CB GLU 183 1.627 4.540 1.435 1.00 0.00 ATOM 1082 1HB GLU 183 1.672 5.274 0.643 1.00 0.00 ATOM 1083 2HB GLU 183 2.579 4.520 1.946 1.00 0.00 ATOM 1084 QB GLU 183 2.125 4.897 1.295 1.00 0.00 ATOM 1085 CG GLU 183 0.570 4.982 2.431 1.00 0.00 ATOM 1086 1HG GLU 183 0.200 4.114 2.955 1.00 0.00 ATOM 1087 2HG GLU 183-0.241 5.454 1.896 1.00 0.00 ATOM 1088 QG GLU 183-0.021 4.784 2.426 1.00 0.00 ATOM 1089 CD GLU 183 1.114 5.962 3.444 1.00 0.00 ATOM 1090 OE1 GLU 183 2.172 6.569 3.169 1.00 0.00 ATOM 1091 OE2 GLU 183 0.483 6.125 4.506 1.00 0.00 ATOM 1092 C GLU 183 2.045 2.084 1. 654 1.00 0.00 ATOM 1093 O GLU 183 2.015 2.123 2.876 1.00 0.00 ATOM 1094 N PHE 184 2.611 1.095 0.995 1.00 0.00 ATOM 1095 H PHE 184 2.578 1.090 0.021 1.00 0.00 ATOM 1096 CA PHE 184 3.232-0.019 1.697 1.00 0.00 ATOM 1097 HA PHE 184 3.105 0.157 2.752 1.00 0.00 ATOM 1098 CB PHE 184 2.525-1.329 1.332 1.00 0.00 ATOM 1099 1HB PHE 184 1.646-1.439 1.950 1.00 0.00 ATOM 1100 2HB PHE 184 3.194-2.155 1.532 1.00 0.00 ATOM 1101 QB PHE 184 2.420-1.797 1.741 1.00 0.00 ATOM 1102 QD PHE 184 2.043-1.435-0.282 1.00 0.00 ATOM 1103 QE PHE 184 1. 329-1. 632-2. 624 1. 00 0. 00 ATOM 1104 QR PHE 184 1.543-1.575-1.922 1. 00 0. 00 ATOM 1105 CG PHE 184 2.094-1.425-0.116 1. 00 0. 00 ATOM 1106 CD1 PHE 184 1.051-0.651-0.609 1. 00 0. 00 ATOM 1107 1HD PHE 184 0.551 0.045 0.048 1. oo o. oo ATOM 1108 CE1 PHE 184 0.647-0.761-1.926 1. 00 0. 00 ATOM 1109 1HE PHE 184-0.165-0.152-2. 296 1. 00 0. 00 ATOM 1110 CZ PHE 184 1.285-1.647-2. 769 1. 00 0. 00

ATOM 1111 HZ PHE 184 0.967-1.740-3.796 1.00 0.00 ATOM 1112 CE2 PHE 184 2.323-2.419-2.295 1.00 0.00 ATOM 1113 2HE PHE 184 2.824-3.113-2.953 1.00 0.00 ATOM 1114 CD2 PHE 184 2.721-2.308-0.977 1.00 0.00 ATOM 1115 2HD PHE 184 3.536-2.915-0.612 1.00 0.00 ATOM 1116 C PHE 184 4.718-0.152 1.407 1.00 0.00 ATOM 1117 O PHE 184 5.161-0.010 0.271 1.00 0.00 ATOM 1118 N VAL 185 5.477-0.454 2.449 1.00 0.00 ATOM 1119 H VAL 185 5.055-0.566 3.328 1.00 0.00 ATOM 1120 CA VAL 185 6.911-0.641 2.330 1.00 0.00 ATOM 1121 HA VAL 185 7.215-0.341 1.336 1.00 0.00 ATOM 1122 CB VAL 185 7.682 0.211 3.367 1.00 0.00 ATOM 1123 HB VAL 185 7.860-0.399 4.245 1.00 0.00 ATOM 1124 QG1 VAL 185 9.340 0.754 2.685 1.00 0.00 ATOM 1125 QG2 VAL 185 6.685 1.715 3.893 1.00 0.00 ATOM 1126 CG1 VAL 185 9.023 0.648 2.814 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.258 0.068 1.935 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.785 0.497 3.564 1.00 0.00 ATOM 1129 3HG1 VAL 185 8.977 1.696 2.554 1.00 0.00 ATOM 1130 CG2 VAL 185 6.876 1.426 3.791 1.00 0. 00 ATOM 1131 1HG2 VAL 185 7.061 2.240 3.105 1.00 0.00 ATOM 1132 2HG2 VAL 185 7.171 1.721 4.788 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.824 1.182 3.786 1.00 0.00 ATOM 1134 QQG VAL 185 8.013 1.234 3.289 1.00 0.00 ATOM 1135 C VAL 185 7.242-2.119 2.523 1.00 0.00 ATOM 1136 O VAL 185 7.192-2.639 3.636 1.00 0.00 ATOM 1137 N CYS 186 7.555-2.804 1.433 1.00 0.00 ATOM 1138 H CYS 186 7.563-2.346 0.562 1.00 0.00 ATOM 1139 CA CYS 186 7.872-4.224 1.498 1.00 0.00 ATOM 1140 HA CYS 186 7.645-4.562 2.501 1.00 0.00 ATOM 1141 CB CYS 186 7.007-5.017 0.507 1.00 0.00 ATOM 1142 1HB CYS 186 6.018-5.131 0.925 1.00 0.00 ATOM 1143 2HB CYS 186 7.443-5.993 0.368 1.00 0.00 ATOM 1144 QB CYS 186 6.730-5.562 0.647 1.00 0.00 ATOM 1145 SG CYS 186 6.827-4.264-1.140 1.00 0.00 ATOM 1146 C CYS 186 9.355-4.461 1.230 1.00 0.00 ATOM 1147 O CYS 186 9.901-3.956 0.258 1.00 0.00 ATOM 1148 N CYS 187 10.009-5.227 2.094 1.00 0.00 ATOM 1149 H CYS 187 9.529-5.609 2.859 1.00 0.00 ATOM 1150 CA CYS 187 11.439-5.504 1.928 1.00 0.00 ATOM 1151 HA CYS 187 11.867-4.685 1.373 1.00 0.00 ATOM 1152 CB CYS 187 12.147-5.607 3.283 1.00 0.00 ATOM 1153 1HB CYS 187 12.950-6.327 3.204 1.00 0.00 ATOM 1154 2HB CYS 187 11.441-5.945 4.026 1.00 0.00 ATOM 1155 QB CYS 187 12.195-6.136 3.615 1.00 0.00 ATOM 1156 SG CYS 187 12.863-4.041 3.872 1.00 0.00 ATOM 1157 C CYS 187 11. 668-6. 785 1.150 1.00 0.00 ATOM 1158 O CYS 187 10.849-7.698 1.201 1. 00 0.00 ATOM 1159 N PRO 188 12.791-6.854 0.413 1.00 0.00 ATOM 1160 CD PRO 188 13.800-5.783 0.305 1.00 0.00 ATOM 1161 CA PRO 188 13.145-8.029-0.391 1.00 0.00 ATOM 1162 HA PRO 188 12.422-8.206-1.175 1.00 0.00 ATOM 1163 CB PRO 188 14.500-7.665-1.010 1.00 0.00 ATOM 1164 1HB PRO 188 14.517-7.976-2.044 1.00 0.00 ATOM 1165 2HB PRO 188 15.287-8.170-0.469 1.00 0.00 ATOM 1166 QB PRO 188 14.902-8.073-1.256 1.00 0.00 ATOM 1167 CG PRO 188 14.621-6.182-0.886 1.00 0.00 ATOM 1168 1HG PRO 188 14.242-5.707-1.779 1.00 0.00 ATOM 1169 2HG PRO 188 15.656-5.912-0.729 1.00 0.00 ATOM 1170 QG PRO 188 14.949-5.809-1.254 1.00 0.00 ATOM 1171 1HD PRO 188 13.328-4.828 0. 130 1.00 0.00 ATOM 1172 2HD PRO 188 14.416-5.741 1.192 1.00 0.00 ATOM 1173 QD PRO 188 13.872-5.284 0.661 1.00 0.00 ATOM 1174 C PRO 188 13.290-9.291 0.456 1.00 0.00 ATOM 1175 O PRO 188 14.061-9.317 1.418 1.00 0.00 ATOM 1176 N LEU 189 12.552-10.327 0.081 1.00 0.00 ATOM 1177 H LEU 189 11.964-10.234-0.701 1.00 0.00 ATOM 1178 CA LEU 189 12.591-11.602 0.776 1.00 0.00 ATOM 1179 HA LEU 189 13.454-11.604 1.424 1.00 0.00 ATOM 1180 CB LEU 189 11.328-11.801 1.617 1.00 0.00 ATOM 1181 1HB LEU 189 10.494-11.935 0.946 1.00 0.00 ATOM 1182 2HB LEU 189 11.163-10.906 2.199 1.00 0.00

ATOM 1183 QB LEU 189 10.828-11.420 1.573 1.00 0.00 ATOM 1184 CG LEU 189 11.371-12.997 2.571 1.00 0.00 ATOM 1185 HG LEU 189 11.898-13.810 2.090 1.00 0.00 ATOM 1186 QD1 LEU 189 12.296-12.556 4.145 1.00 0.00 ATOM 1187 QD2 LEU 189 9.632-13.584 2.971 1.00 0.00 ATOM 1188 CD1 LEU 189 12. 119-12.640 3.844 1.00 0.00 ATOM 1189 1HD1 LEU 189 13.175-12.813 3.700 1.00 0.00 ATOM 1190 2HD1 LEU 189 11.760-13.255 4.656 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.953-11.600 4.079 1.00 0.00 ATOM 1192 CD2 LEU 189 9.964-13.472 2.894 1.00 0.00 ATOM 1193 1HD2 LEU 189 9.417-12.673 3.372 1.00 0.00 ATOM 1194 2HD2 LEU 189 10.016-14.321 3.559 1.00 0.00 ATOM 1195 3HD2 LEU 189 9.462-13.758 1.982 1.00 0.00 ATOM 1196 QQD LEU 189 10.964-13.070 3.558 1.00 0.00 ATOM 1197 C LEU 189 12.725-12.739-0.232 1.00 0.00 ATOM 1198 OT1 LEU 189 13.342-13.768 0.111 1.00 0.00 ATOM 1199 OT2 LEU 189 12.209-12.587-1.361 1.00 0.00 TER ENDMDL MODEL 20 ATOM 1 N SER 124 11.872 16.383 3.374 1.00 0.00 ATOM 2 CA SER 124 11.007 15.175 3.372 1.00 0.00 ATOM 3 HA SER 124 11.605 14.316 3.639 1. 00 0.00 ATOM 4 CB SER 124 9.899 15.375 4.407 1.00 0.00 ATOM 5 1HB SER 124 9.745 14.453 4.951 1.00 0.00 ATOM 6 2HB SER 124 8.984 15.654 3.903 1.00 0.00 ATOM 7 QB SER 124 9.365 15.053 4.427 1.00 0.00 ATOM 8 OG SER 124 10.251 16.401 5.326 1.00 0.00 ATOM 9 HG SER 124 9.552 16.498 5.986 1.00 0.00 ATOM 10 C SER 124 10.420 14.966 1.989 1.00 0.00 ATOM 11 O SER 124 9.292 15.367 1.712 1.00 0.00 ATOM 12 1HT SER 124 11.851 16.840 2.433 1.00 0.00 ATOM 13 2HT SER 124 12.854 16.122 3.595 1.00 0.00 ATOM 14 3HT SER 124 11.530 17.061 4.087 1.00 0.00 ATOM 15 N ASP 125 11.222 14.383 1.115 1.00 0.00 ATOM 16 H ASP 125 12.127 14.126 1.393 1.00 0.00 ATOM 17 CA ASP 125 10.831 14.169-0.268 1.00 0.00 ATOM 18 HA ASP 125 9.830 14.552-0.398 1.00 0.00 ATOM 19 CB ASP 125 11.788 14.959-1.167 1.00 0.00 ATOM 20 1HB ASP 125 11.227 15.689-1.731 1.00 0.00 ATOM 21 2HB ASP 125 12.278 14.279-1.849 1.00 0.00 ATOM 22 QB ASP 125 11.753 14.984-1.790 1.00 0.00 ATOM 23 CG ASP 125 12.853 15.684-0.360 1.00 0.00 ATOM 24 OD1 ASP 125 14.004 15.214-0.344 1.00 0. 00 ATOM 25 OD2 ASP 125 12.521 16.700 0.298 1.00 0.00 ATOM 26 C ASP 125 10.854 12.689-0.638 1.00 0.00 ATOM 27 O ASP 125 10.874 12.331-1.814 1.00 0.00 ATOM 28 N ALA 126 10.848 11 : 830 0.372 1.00 0.00 ATOM 29 H ALA 126 10.828 12.169 1.287 1.00 0. 00 ATOM 30 CA ALA 126 10.868 10.392 0.145 1.00 0.00 ATOM 31 HA ALA 126 11.335 10.216-0.814 1.00 0.00 ATOM 32 QB ALA 126 11.897 9.528 1.463 1.00 0.00 ATOM 33 CB ALA 126 11.701 9.695 1.212 1.00 0.00 ATOM 34 1HB ALA 126 11.066 9.427 2.044 1.00 0.00 ATOM 35 2HB ALA 126 12.483 10.357 1.551 1.00 0.00 ATOM 36 3HB ALA 126 12.143 8.801 0.795 1.00 0.00 ATOM 37 C ALA 126 9.459 9.816 0.119 1.00 0.00 ATOM 38 O ALA 126 8.916 9.438 1.157 1.00 0.00 ATOM 39 N LEU 127 8.875 9.746-1.071 1.00 0.00 ATOM 40 H LEU 127 9.361 10.060-1.859 1.00 0.00 ATOM 41 CA LEU 127 7.531 9.205-1.234 1.00 0.00 ATOM 42 HA LEU 127 7.076 9.157-0.258 1.00 0.00 ATOM 43 CB LEU 127 6.690 10.116-2.134 1.00 0.00 ATOM 44 1HB LEU 127 6.831 9.799-3.157 1.00 0.00 ATOM 45 2HB LEU 127 7.058 11.126-2.033 1.00 0.00 ATOM 46 QB LEU 127 6.945 10.462-2.595 1.00 0.00 ATOM 47 CG LEU 127 5.189 10.114-1.836 1.00 0.00 ATOM 48 HG LEU 127 4.910 9.152-1.429 1.00 0.00 ATOM 49 QD1 LEU 127 4.762 11.426-0.561 1.00 0.00 ATOM 50 QD2 LEU 127 4.199 10.386-3.412 1.00 0.00 ATOM 51 CD1 LEU 127 4.844 11.176-0.805 1.00 0.00 ATOM 52 1HD1 LEU 127 5.451 11.032 0.077 1.00 0.00

ATOM 53 2HD1 LEU 127 3.800 11.093-0.541 1.00 0.00 ATOM 54 3HD1 LEU 127 5.034 12.155-1.218 1.00 0.00 ATOM 55 CD2 LEU 127 4.389 10.334-3.110 1.00 0.00 ATOM 56 1HD2 LEU 127 4.794 9.720-3.901 1.00 0.00 ATOM 57 2HD2 LEU 127 4.445 11.374-3.397 1.00 0.00 ATOM 58 3HD2 LEU 127 3.357 10.064-2.938 1.00 0.00 ATOM 59 QQD LEU 127 4.480 10.906-1.987 1.00 0.00 ATOM 60 C LEU 127 7.588 7.800-1.822 1.00 0.00 ATOM 61 O LEU 127 6.569 7.233-2.212 1.00 0.00 ATOM 62 N LEU 128 8.788 7.242-1.883 1.00 0.00 ATOM 63 H LEU 128 9.563 7.738-1.555 1.00 0.00 ATOM 64 CA LEU 128 8.980 5.907-2.419 1.00 0.00 ATOM 65 HA LEU 128 8.036 5.389-2.369 1.00 0.00 ATOM 66 CB LEU 128 9.433 5.988-3.882 1.00 0.00 ATOM 67 1HB LEU 128 10.512 5.986-3.900 1.00 0.00 ATOM 68 2HB LEU 128 9.085 6.926-4.292 1.00 0.00 ATOM 69 QB LEU 128 9.799 6.456-4.096 1.00 0.00 ATOM 70 CG LEU 128 8.934 4.854-4.783 1.00 0.00 ATOM 71 HG LEU 128 8.538 4.056-4.169 1.00 0.00 ATOM 72 QD1 LEU 128 7.545 5.466-5.891 1.00 0.00 ATOM 73 QD2 LEU 128 10.339 4.161-5.821 1.00 0.00 ATOM 74 CD1 LEU 128 7.811 5.349-5.679 1.00 0.00 ATOM 75 1HD1 LEU 128 7.225 4.508-6.019 1.00 0.00 ATOM 76 2HD1 LEU 128 8.230 5.863-6.531 1.00 0.00 ATOM 77 3HD1 LEU 128 7.180 6.027-5.123 1.00 0.00 ATOM 78 CD2 LEU 128 10.070 4.293-5.622 1.00 0.00 ATOM 79 1HD2 LEU 128 10.082 4.784-6.584 1.00 0.00 ATOM 80 2HD2 LEU 128 9.926 3.232-5.760 1.00 0.00 ATOM 81 3HD2 LEU 128 11.010 4.467-5.119 1.00 0.00 ATOM 82 QQD LEU 128 8.942 4.813-5.856 1.00 0.00 ATOM 83 C LEU 128 9.998 5.156-1.566 1.00 0.00 ATOM 84 O LEU 128 10.106 5.421-0.370 1.00 0.00 ATOM 85 N VAL 129 10.722 4.220-2.182 1.00 0.00 ATOM 86 H VAL 129 10.563 4.065-3.135 1.00 0.00 ATOM 87 CA VAL 129 11.733 3.402-1.492 1.00 0.00 ATOM 88 HA VAL 129 11.213 2.664-0.901 1.00 0.00 ATOM 89 CB VAL 129 12.627 2.657-2.511 1.00 0.00 ATOM 90 HB VAL 129 13.189 3.395-3.068 1.00 0.00 ATOM 91 QG1 VAL 129 13.856 1.527-1.641 1.00 0.00 ATOM 92 QG2 VAL 129 11.579 1.678-3.728 1.00 0.00 ATOM 93 CG1 VAL 129 13.620 1.743-1.808 1.00 0.00 ATOM 94 1HG1 VAL 129 14.362 2.342-1.298 1.00 0.00 ATOM 95 2HG1 VAL 129 14.108 1.112-2.536 1.00 0.00 ATOM 96 3HG1 VAL 129 13.099 1.128-1.089 1.00 0.00 ATOM 97 CG2 VAL 129 11.779 1.866-3.495 1.00 0.00 ATOM 98 1HG2 VAL 129 12.075 2.112-4.504 1.00 0.00 ATOM 99 2HG2 VAL 129 10.738 2.115-3.355 1.00 0.00 ATOM 100 3HG2 VAL 129 11.924 0.809-3.325 1.00 0.00 ATOM 101 QQG VAL 129 12.718 1.603-2.685 1.00 0.00 ATOM 102 C VAL 129 12.627 4.234-0.561 1.00 0.00 ATOM 103 O VAL 129 13.416 5.058-1.019 1. 00 0.00 ATOM 104 N PRO 130 12.495 4.025 0.766 1.00 0.00 ATOM 105 CD PRO 130 11.568 3.088 1.396 1.00 0.00 ATOM 106 CA PRO 130 13.271 4.740 1.776 1.00 0.00 ATOM 107 HA PRO 130 13.440 5.759 1.493 1.00 0.00 ATOM 108 CB PRO 130 12.364 4.697 3.020 1.00 0.00 ATOM 109 1HB PRO 130 12.021 5.697 3.243 1.00 0.00 ATOM 110 2HB PRO 130 12.928 4.317 3.860 1.00 0.00 ATOM 111 QB PRO 130 12.475 5.007 3.551 1.00 0.00 ATOM 112 CG PRO 130 11.214 3.791 2.679 1.00 0.00 ATOM 113 1HG PRO 130 10.316 4.380 2.545 1.00 0.00 ATOM 114 2HG PRO 130 11.070 3.070 3.470 1.00 0.00 ATOM 115 QG PRO 130 10.693 3.725 3.007 1.00 0.00 ATOM 116 1HD PRO 130 10.689 2.947 0.785 1. 00 0. 00 ATOM 117 2HD PRO 130 12.049 2.142 1.597 1.00 0.00 ATOM 118 QD PRO 130 11.369 2.544 1.191 1.00 0.00 ATOM 119 C PRO 130 14.617 4.078 2.063 1.00 0.00 ATOM 120 O PRO 130 15.631 4.415 1.458 1.00 0.00 ATOM 121 N ASP 131 14.605 3.145 3.002 1.00 0.00 ATOM 122 H ASP 131 13.760 2.945 3.441 1.00 0.00 ATOM 123 CA ASP 131 15.812 2.422 3.401 1. 00 0. 00 ATOM 124 HA ASP 131 16.648 3.102 3.320 1.00 0.00

ATOM 125 CB ASP 131 15.679 1.964 4.862 1.00 0.00 ATOM 126 1HB ASP 131 14.884 1.236 4.932 1.00 0.00 ATOM 127 2HB ASP 131 15.433 2.816 5.476 1.00 0.00 ATOM 128 QB ASP 131 15.159 2.026 5.204 1.00 0.00 ATOM 129 CG ASP 131 16.945 1.341 5.407 1.00 0.00 ATOM 130 OD1 ASP 131 18.037 1.629 4.876 1.00 0.00 ATOM 131 OD2 ASP 131 16.846 0.541 6.361 1.00 0.00 ATOM 132 C ASP 131 16.061 1.225 2.477 1.00 0.00 ATOM 133 O ASP 131 16. 556 1.383 1.364 1.00 0.00 ATOM 134 N LYS+ 132 15.709 0.026 2.934 1.00 0.00 ATOM 135 H LYS+ 132 15.317-0.049 3.827 1.00 0.00 ATOM 136 CA LYS+ 132 15.902-1.178 2.126 1.00 0.00 ATOM 137 HA LYS+ 132 16.431-0.887 1.229 1.00 0.00 ATOM 138 CB LYS+ 132 16.737-2.221 2.879 1.00 0.00 ATOM 139 1HB LYS+ 132 17.738-2.220 2.473 1.00 0.00 ATOM 140 2HB LYS+ 132 16.297-3.195 2.719 1.00 0.00 ATOM 141 QB LYS+ 132 17.018-2.708 2.596 1.00 0.00 ATOM 142 CG LYS+ 132 16.828-1.980 4.379 1.00 0.00 ATOM 143 1HG LYS+ 132 15. 910-2. 312 4.843 1.00 0.00 ATOM 144 2HG LYS+ 132 16. 960-0. 922 4.557 1.00 0.00 ATOM 145 QG LYS+ 132 16.435-1.617 4.700 1.00 0.00 ATOM 146 CD LYS+ 132 17.995-2.733 4.998 1.00 0.00 ATOM 147 1HD LYS+ 132 18.161-3.641 4.436 1.00 0.00 ATOM 148 2HD LYS+ 132 17.748-2.981 6.020 1.00 0.00 ATOM 149 QD LYS+ 132 17.955-3.311 5.228 1.00 0.00 ATOM 150 CE LYS+ 132 19.271-1.902 4.984 1.00 0.00 ATOM 151 1HE LYS+ 132 19.512-1.656 3.960 1.00 0.00 ATOM 152 2HE LYS+ 132 20.072-2.488 5.410 1. 00 0. 00 ATOM 153 QE LYS+ 132 19.792-2.072 4.685 1.00 0.00 ATOM 154 NZ LYS+ 132 19.127-0.642 5.763 1.00 0.00 ATOM 155 1HZ LYS+ 132 19.892-0.549 6.455 1.00 0.00 ATOM 156 2HZ LYS+ 132 18.210-0.627 6.269 1.00 0.00 ATOM 157 3HZ LYS+ 132 19.147 0.187 5.123 1.00 0.00 ATOM 158 QZ LYS+ 132 19.083-0.330 5.949 1.00 0.00 ATOM 159 C LYS+ 132 14.562-1.782 1.726 1.00 0.00 ATOM 160 0 LYS+ 132 14.501-2.785 1.014 1.00 0.00 ATOM 161 N CYS 133 13.490-1.165 2.186 1.00 0.00 ATOM 162 H CYS 133 13.603-0.371 2.743 1.00 0.00 ATOM 163 CA CYS 133 12.148-1.630 1.877 1.00 0.00 ATOM 164 HA CYS 133 12.205-2.682 1.641 1.00 0.00 ATOM 165 CB CYS 133 11.224-1.429 3.080 1.00 0.00 ATOM 166 1HB CYS 133 10.226-1.224 2.720 1.00 0.00 ATOM 167 2HB CYS 133 11.569-0.579 3.644 1.00 0.00 ATOM 168 QB CYS 133 10.898-0.902 3.182 1.00 0.00 ATOM 169 SG CYS 133 11.112-2.838 4.235 1.00 0.00 ATOM 170 C CYS 133 11.602-0.876 0.667 1.00 0.00 ATOM 171 O CYS 133 12.015 0.244 0.392 1.00 0.00 ATOM 172 N LYS+ 134 10.672-1.489-0.045 1.00 0.00 ATOM 173 H LYS+ 134 10.372-2.382 0.230 1.00 0.00 ATOM 174 CA LYS+ 134 10.069-0.875-1.220 1.00 0.00 ATOM 175 HA LYS+ 134 10.762-0.144-1.610 1.00 0.00 ATOM 176 CB LYS+ 134 9.793-1.935-2.291 1.00 0.00 ATOM 177 1HB LYS+ 134 8.800-2.334-2.132 1.00 0.00 ATOM 178 2HB LYS+ 134 10.511-2.733-2.184 1.00 0.00 ATOM 179 QB LYS+ 134 9.656-2.534-2.158 1.00 0.00 ATOM 180 CG LYS+ 134 9.869-1.409-3.717 1.00 0.00 ATOM 181 1HG LYS+ 134 10.906-1.317-4.004 1.00 0.00 ATOM 182 2HG LYS+ 134 9.395-0.438-3.756 1.00 0.00 ATOM 183 QG LYS+ 134 10. 151-0. 878-3.880 1.00 0.00 ATOM 184 CD LYS+ 134 9.162-2.340-4.691 1.00 0. 00 ATOM 185 1HD LYS+ 134 8.317-1.819-5.121 1.00 0.00 ATOM 186 2HD LYS+ 134 8.812-3.210-4.155 1.00 0.00 ATOM 187 QD LYS+ 134 8.565-2.515-4.638 1.00 0.00 ATOM 188 CE LYS+ 134 10. 085-2. 790-5.815 1.00 0.00 ATOM 189 1HE LYS+ 134 10.126-2.012-6.563 1. 00 0. 00 ATOM 190 2HE LYS+ 134 9.680-3.690-6.255 1. 00 0. 00 ATOM 191 QE LYS+ 134 9.903-2.851-6.409 1.00 0.00 ATOM 192 NZ LYS+ 134 11.467-3.069-5.326 1. 00 0. 00 ATOM 193 1HZ LYS+ 134 11.792-3.994-5.676 1.00 0.00 ATOM 194 2HZ LYS+ 134 11.483-3.081-4.287 1.00 0.00 ATOM 195 3HZ LYS+ 134 12. 123-2. 334-5.663 1. 00 o. oo ATOM 196 QZ LYS+ 134 11.799-3.137-5.209 1. oo o. oo

ATOM 197 C LYS+ 134 8.775-0.180-0.836 1.00 0.00 ATOM 198 0 LYS+ 134 7.808-0.831-0.462 1.00 0.00 ATOM 199 N PHE 135 8.766 1.138-0.922 1.00 0.00 ATOM 200 H PHE 135 9.571 1.605-1.224 1.00 0.00 ATOM 201 CA PHE 135 7.586 1.913-0.571 1.00 0.00 ATOM 202 HA PHE 135 6. 997 1.331 0.123 1.00 0.00 ATOM 203 CB PHE 135 8.009 3.219 0.103 1.00 0.00 ATOM 204 1HB PHE 135 8.465 3.859-0.639 1.00 0.00 ATOM 205 2HB PHE 135 8.738 2.997 0.866 1.00 0.00 ATOM 206 QB PHE 135 8.602 3.428 0.113 1.00 0.00 ATOM 207 QD PHE 135 6. 774 4.081 0.826 1.00 0.00 ATOM 208 QE PHE 135 4.976 5.364 1.908 1.00 0.00 ATOM 209 QR PHE 135 5.514 4.979 1.583 1.00 0.00 ATOM 210 CG PHE 135 6.896 3.993 0.753 1.00 0.00 ATOM 211 CD1 PHE 135 6.971 5.374 0.850 1.00 0.00 ATOM 212 1HD PHE 135 7.831 5.888 0.444 1.00 0.00 ATOM 213 CE1 PHE 135 5.963 6.097 1.456 1.00 0.00 ATOM 214 1HE PHE 135 6.034 7.173 1.526 1.00 0.00 ATOM 215 CZ PHE 135 4.864 5.443 1.973 1.00 0.00 ATOM 216 HZ PHE 135 4.072 6.006 2.450 1.00 0. 00 ATOM 217 CE2 PHE 135 4.778 4.069 1.883 1.00 0.00 ATOM 218 2HE PHE 135 3.918 3.555 2.290 1.00 0.00 ATOM 219 CD2 PHE 135 5.789 3.351 1.277 1.00 0.00 ATOM 220 2HD PHE 135 5.716 2.275 1.209 1. 00 0.00 ATOM 221 C PHE 135 6.752 2.197-1.808 1.00 0.00 ATOM 222 O PHE 135 7.189 2.908-2.715 1.00 0.00 ATOM 223 N LEU 136 5.554 1.637-1.835 1.00 0.00 ATOM 224 H LEU 136 5.264 1.083-1.075 1.00 0.00 ATOM 225 CA LEU 136 4.649 1.822-2.951 1.00 0.00 ATOM 226 HA LEU 136 5.197 2.303-3.747 1.00 0.00 ATOM 227 CB LEU 136 4.100 0.479-3.454 1.00 0.00 ATOM 228 1HB LEU 136 3.381 0.685-4.234 1.00 0.00 ATOM 229 2HB LEU 136 3.580 0.004-2.635 1.00 0.00 ATOM 230 QB LEU 136 3.481 0.344-3.435 1.00 0.00 ATOM 231 CG LEU 136 5.131-0.519-4.009 1.00 0.00 ATOM 232 HG LEU 136 4.649-1.146-4.745 1.00 0.00 ATOM 233 QD1 LEU 136 6.564 0.353-4.849 1.00 0.00 ATOM 234 QD2 LEU 136 5.770-1.631-2.640 1.00 0.00 ATOM 235 CD1 LEU 136 6.289 0.188-4.690 1.00 0.00 ATOM 236 1HD1 LEU 136 6.431 1.160-4.242 1.00 0.00 ATOM 237 2HD1 LEU 136 6.075 0.300-5.741 1.00 0.00 ATOM 238 3HD1 LEU 136 7.186-0.401-4.563 1.00 0.00 ATOM 239 CD2 LEU 136 5.648-1.418-2.903 1.00 0.00 ATOM 240 1HD2 LEU 136 4.816-1.776-2.314 1.00 0.00 ATOM 241 2HD2 LEU 136 6.322-0.859-2.271 1.00 0.00 ATOM 242 3HD2 LEU 136 6.171-2.257-3.335 1.00 0.00 ATOM 243 QQD LEU 136 6.167-0.639-3.745 1.00 0.00 ATOM 244 C LEU 136 3.503 2.722-2.528 1.00 0.00 ATOM 245 0LEU 136 2.429 2.250-2.169 1.00 0.00 ATOM 246 N HIS+ 137 3.746 4.019-2.572 1.00 0.00 ATOM 247 H HIS+ 137 4.627 4.330-2.866 1.00 0. 00 ATOM 248 CA HIS+ 137 2.739 4.999-2.201 1.00 0.00 ATOM 249 HA HIS+ 137 2.044 4.534-1.509 1.00 0.00 ATOM 250 CB HIS+ 137 3.405 6.212-1.534 1.00 0.00 ATOM 251 1HB HIS+ 137 4.032 6.704-2.260 1.00 0.00 ATOM 252 2HB HIS+ 137 4.019 5.868-0.714 1.00 0.00 ATOM 253 QB HIS+ 137 4.026 6.286-1.487 1.00 0.00 ATOM 254 CG HIS+ 137 2.446 7.230-0.987 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.577 7.962-1.771 1.00 0.00 ATOM 256 CD2 HIS+ 137 2.217 7.623 0.284 1.00 0.00 ATOM 257 1HD HIS+ 137 1.499 7.913-2.754 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.856 8.756-1.000 1.00 0.00 ATOM 259 NE2 HIS+ 137 1.221 8.568 0.257 1.00 0.00 ATOM 260 2HD HIS+ 137 2.720 7.254 1.168 1.00 0.00 ATOM 261 1HE HIS+ 137 0.092 9.442-1.342 1.00 0.00 ATOM 262 2HE HIS+ 137 0.664 8.803 1.035 1.00 0.00 ATOM 263 C HIS+ 137 2.000 5.439-3.453 1.00 0.00 ATOM 264 O HIS+ 137 2.548 6.182-4.270 1.00 0.00 ATOM 265 N GLN 138 0.774 4.971-3.620 1.00 0.00 ATOM 266 H GLN 138 0.387 4.369-2.944 1.00 0.00 ATOM 267 CA GLN 138-0. 007 5.325-4.796 1.00 0.00 ATOM 268 HA GLN 138 0.414 6.234-5.203 1.00 0.00

ATOM 269 CB GLN 138 0.086 4.222-5.853 1.00 0.00 ATOM 270 1HB GLN 138-0.749 4.321-6.531 1.00 0.00 ATOM 271 2HB GLN 138 0.027 3.264-5.362 1.00 0.00 ATOM 272 QB GLN 138-0.361 3.792-5.947 1.00 0.00 ATOM 273 CG GLN 138 1.371 4.265-6.668 1.00 0.00 ATOM 274 1HG GLN 138 1.919 5.158-6.403 1.00 0.00 ATOM 275 2HG GLN 138 1.117 4.298-7.717 1.00 0.00 ATOM 276 QG GLN 138 1.518 4.728-7.060 1.00 0.00 ATOM 277 CD GLN 138 2.259 3.061-6.424 1.00 0.00 ATOM 278 OE1 GLN 138 1.868 1.927-6.690 1.00 0.00 ATOM 279 NE2 GLN 138 3.462 3.297-5.914 1.00 0.00 ATOM 280 1HE2 GLN 138 3.714 4.226-5.722 1.00 0.00 ATOM 281 2HE2 GLN 138 4.051 2.532-5.751 1.00 0.00 ATOM 282 QE2 GLN 138 3.883 3.379-5.737 1.00 0.00 ATOM 283 C GLN 138-1.462 5.588-4.438 1.00 0.00 ATOM 284 O GLN 138-2.080 4.842-3.672 1.00 0.00 ATOM 285 N GLU 139-1.995 6. 660-4.996 1.00 0.00 ATOM 286 H GLU 139-1.439 7.211-5.586 1.00 0.00 ATOM 287 CA GLU 139-3.370 7.060-4.753 1.00 0.00 ATOM 288 HA GLU 139-3.673 6.637-3.807 1.00 0.00 ATOM 289 CB GLU 139-3.463 8.591-4.671 1.00 0.00 ATOM 290 1HB GLU 139-3.596 8.874-3.637 1.00 0.00 ATOM 291 2HB GLU 139-4.322 8.918-5.237 1.00 0.00 ATOM 292 QB GLU 139-3.959 8.896-4.437 1.00 0.00 ATOM 293 CG GLU 139-2. 235 9.322-5.207 1.00 0.00 ATOM 294 1HG GLU 139-2.539 10.298-5.556 1.00 0.00 ATOM 295 2HG GLU 139-1.827 8.759-6.032 1.00 0.00 ATOM 296 QG GLU 139-2.183 9.528-5.794 1.00 0.00 ATOM 297 CD GLU 139-1.154 9.500-4.160 1.00 0.00 ATOM 298 OE1 GLU 139-0.146 8.764-4.218 1.00 0.00 ATOM 299 OE2 GLU 139-1.319 10.367-3.280 1.00 0.00 ATOM 300 C GLU 139-4.293 6.529-5.851 1.00 0.00 ATOM 301 O GLU 139-4.341 7.069-6.955 1.00 0.00 ATOM 302 N ARG+ 140-5.028 5.473-5.532 1.00 0.00 ATOM 303 H ARG+ 140-4.950 5.096-4.631 1.00 0.00 ATOM 304 CA ARG+ 140-5.959 4.857-6.475 1.00 0.00 ATOM 305 HA ARG+ 140-5.629 5.081-7.479 1.00 0.00 ATOM 306 CB ARG+ 140-5.976 3.336-6.264 1.00 0.00 ATOM 307 1HB ARG+ 140-6.710 3.106-5.503 1.00 0.00 ATOM 308 2HB ARG+ 140-5.003 3.025-5.916 1.00 0.00 ATOM 309 QB ARG+ 140-5.856 3.065-5.710 1.00 0.00 ATOM 310 CG ARG+ 140-6.315 2.527-7.507 1.00 0.00 ATOM 311 1HG ARG+ 140-6.086 3.115-8.383 1.00 0.00 ATOM 312 2HG ARG+ 140-7.370 2.297-7.497 1.00 0.00 ATOM 313 QG ARG+ 140-6.728 2.706-7.940 1.00 0.00 ATOM 314 CD ARG+ 140-5.524 1.227-7.556 1.00 0.00 ATOM 315 1HD ARG+ 140-4.822 1.216-6.736 1.00 0.00 ATOM 316 2HD ARG+ 140-4.981 1.191-8.491 1.00 0.00 ATOM 317 QD ARG+ 140-4.901 1.203-7.614 1.00 0.00 ATOM 318 NE ARG+ 140-6.385 0.044-7.465 1.00 0.00 ATOM 319 HE ARG+ 140-6.566-0.444-8.300 1.00 0.00 ATOM 320 CZ ARG+ 140-6.924-0.406-6.327 1.00 0. 00 ATOM 321 NH1 ARG+ 140-6.727 0.254-5.191 1.00 0.00 ATOM 322 1HH1 ARG+ 140-6.176 1.089-5.188 1.00 0.00 ATOM 323 2HH1 ARG+ 140-7.137-0.076-4.335 1. 00 0. 00 ATOM 324 QH1 ARG+ 140-6.656 0.506-4.762 1.00 0.00 ATOM 325 NH2 ARG+ 140-7.674-1.505-6.332 1.00 0.00 ATOM 326 1HH2 ARG+ 140-7.837-2.000-7.186 1.00 0.00 ATOM 327 2HH2 ARG+ 140-8.088-1.837-5.480 1.00 0.00 ATOM 328 QH2 ARG+ 140-7.962-1.919-6.333 1.00 0.00 ATOM 329 C ARG+ 140-7.361 5.424-6.262 1.00 0.00 ATOM 330 O ARG+ 140-8.210 4.775-5.646 1.00 0.00 ATOM 331 N MET 141-7.601 6.636-6.761 1.00 0.00 ATOM 332 H MET 141-6.883 7.103-7.240 1. 00 0. 00 ATOM 333 CA MET 141-8.905 7.293-6.607 1.00 0.00 ATOM 334 HA MET 141-9.216 7.160-5.584 1.00 0.00 ATOM 335 CB MET 141-8.778 8.793-6.894 1.00 0. 00 ATOM 336 1HB MET 141-8.954 8.959-7.948 1.00 0. 00 ATOM 337 2HB MET 141-7.777 9.112-6.651 1.00 0.00 ATOM 338 QB MET 141-8.365 9.035-7.300 1.00 0.00 ATOM 339 CG MET 141-9. 758 9.653-6.108 1.00 0. 00 ATOM 340 1HG MET 141-9.422 9.714-5.084 1. 00 0. 00

ATOM 341 2HG MET 141-10. 729 9.182-6.140 1.00 0.00 ATOM 342 QG MET 141-10.075 9.448-5.612 1.00 0.00 ATOM 343 SD MET 141-9.913 11.325-6.767 1.00 0.00 ATOM 344 QE MET 141-7.865 11.982-6.725 1.00 0.00 ATOM 345 CE MET 141-8.208 11.873-6.731 1.00 0.00 ATOM 346 1HE MET 141-7.906 12.048-5.709 1.00 0.00 ATOM 347 2HE MET 141-8.111 12.788-7.297 1.00 0.00 ATOM 348 3HE MET 141-7.577 11.112-7.167 1.00 0.00 ATOM 349 C MET 141-9.967 6.678-7.521 1.00 0.00 ATOM 350 O MET 141-10.874 7.368-7.989 1.00 0.00 ATOM 351 N ASP 142-9.846 5.385-7.762 1.00 0.00 ATOM 352 H ASP 142-9.103 4.896-7.355 1.00 0.00 ATOM 353 CA ASP 142-10.772 4.665-8.612 1.00 0.00 ATOM 354 HA ASP 142-11. 444 5.379-9.063 1.00 0.00 ATOM 355 CB ASP 142-10.010 3.926-9.713 1.00 0.00 ATOM 356 1HB ASP 142-10.640 3.855-10.578 1.00 0.00 ATOM 357 2HB ASP 142-9.768 2.933-9.369 1.00 0.00 ATOM 358 QB ASP 142-10.204 3.394-9.974 1.00 0.00 ATOM 359 CG ASP 142-8.723 4.616-10.115 1.00 0.00 ATOM 360 OD1 ASP 142-8.739 5.. 371-11.105 1.00 0. 00 ATOM 361 OD2 ASP 142-7.697 4.398-9.437 1.00 0.00 ATOM 362 C ASP 142-11.575 3.663-7.803 1.00 0.00 ATOM 363 O ASP 142-12.781 3.508-7.994 1.00 0.00 ATOM 364 N VAL 143-10.893 2.965-6.907 1.00 0.00 ATOM 365 H VAL 143-9.931 3.123-6.808 1.00 0.00 ATOM 366 CA VAL 143-11.540 1.956-6.084 1.00 0.00 ATOM 367 HA VAL 143-12.542 1.822-6.466 1.00 0.00 ATOM 368 CB VAL 143-10.806 0.604-6.184 1.00 0.00 ATOM 369 HB VAL 143-10.077 0.549-5.387 1.00 0.00 ATOM 370 QG1 VAL 143-12.014-0.821-5.977 1.00 0.00 ATOM 371 QG2 VAL 143-9.902 0.459-7.828 1.00 0.00 ATOM 372 CG1 VAL 143-11.783-0.547-6.016 1.00 0.00 ATOM 373 1HG1 VAL 143-12.730-0.168-5.665 1.00 0.00 ATOM 374 2HG1 VAL 143-11.389-1.254-5.298 1.00 0.00 ATOM 375 3HG1 VAL 143-11.923-1.040-6.966 1.00 0.00 ATOM 376 CG2 VAL 143-10.074 0.486-7.514 1.00 0.00 ATOM 377 1HG2 VAL 143-10.254-0.490-7.938 1.00 0.00 ATOM 378 2HG2 VAL 143-9.015 0.621-7.354 1.00 0.00 ATOM 379 3HG2 VAL 143-10.436 1.247-8.191 1.00 0.00 ATOM 380 QQG VAL 143-10.958-0.181-6.902 1.00 0.00 ATOM 381 C VAL 143-11. 630 2.400-4.623 1.00 0.00 ATOM 382 O VAL 143-10.758 3.108-4.124 1.00 0.00 ATOM 383 N CYS 144-12.697 1.981-3.948 1.00 0.00 ATOM 384 H CYS 144-13. 355 1.421-4.403 1.00 0.00 ATOM 385 CA CYS 144-12.919 2.336-2.548 1.00 0.00 ATOM 386 HA CYS 144-12.012 2.786-2.166 1.00 0.00 ATOM 387 CB CYS 144-14.062 3.346-2.438 1.00 0.00 ATOM 388 1HB CYS 144-14.208 3.599-1.398 1.00 0.00 ATOM 389 2HB CYS 144-14.966 2.896-2.821 1.00 0.00 ATOM 390 QB CYS 144-14.587 3.247-2.110 1.00 0.00 ATOM 391 SG CYS 144-13.785 4.896-3.355 1.00 0.00 ATOM 392 C CYS 144-13.248 1.105-1.713 1.00 0.00 ATOM 393 O CYS 144-14.417 0.790-1.489 1.00 0.00 ATOM 394 N GLU 145-12.216 0.415-1.256 1.00 0.00 ATOM 395 H GLU 145-11.307 0.715-1.469 1.00 0.00 ATOM 396 CA GLU 145-12.391-0.785-0.454 1.00 0.00 ATOM 397 HA GLU 145-13.430-1.073-0.515 1.00 0.00 ATOM 398 CB GLU 145-11. 531-1.908-1.033 1.00 0.00 ATOM 399 1HB GLU 145-11.323-2.624-0.256 1.00 0.00 ATOM 400 2HB GLU 145-10.596-1.487-1.378 1.00 0.00 ATOM 401 QB GLU 145-10.959-2.056-0.817 1.00 0.00 ATOM 402 CG GLU 145-12.181-2.642-2.200 1.00 0.00 ATOM 403 1HG GLU 145-12.736-1.931-2.793 1.00 0.00 ATOM 404 2HG GLU 145-12.856-3.388-1.809 1.00 0.00 ATOM 405 QG GLU 145-12.796-2.660-2.301 1.00 0.00 ATOM 406 CD GLU 145-11. 168-3.331-3.094 1.00 0.00 ATOM 407 OBI GLU 145-10.355-4.121-2.574 1.00 0.00 ATOM 408 OE2 GLU 145-11.177-3.072-4.315 1.00 0.00 ATOM 409 C GLU 145-12.029-0.537 1.012 1.00 0.00 ATOM 410 O GLU 145-11.791 0.601 1.421 1.00 0.00 ATOM 411 N THR 146-12.005-1.612 1.797 1.00 0.00 ATOM 412 H THR 146-12.214-2.486 1.406 1.00 0.00

ATOM 413 CA THR 146-11.690-1.541 3.223 1.00 0.00 ATOM 414 HA THR 146-12.181-0.674 3.638 1.00 0.00 ATOM 415 CB THR 146-12.215-2.803 3.917 1.00 0.00 ATOM 416 HB THR 146-11.435-3.552 3.905 1.00 0.00 ATOM 417 QG2 THR 146-12.720-2.537 5.703 1.00 0.00 ATOM 418 OG1 THR 146-13.338-3.324 3.224 1.00 0.00 ATOM 419 1HG THR 146-14.014-3.582 3.861 1.00 0.00 ATOM 420 CG2 THR 146-12.622-2.588 5.357 1.00 0.00 ATOM 421 1HG2 THR 146-13.338-1.779 5.417 1.00 0.00 ATOM 422 2HG2 THR 146-11.753-2.339 5.947 1.00 0.00 ATOM 423 3HG2 THR 146-13. 069-3.492 5.746 1.00 0.00 ATOM 424 C THR 146-10. 185-1.428 3.455 1.00 0.00 ATOM 425 O THR 146-9.386-1.637 2.541 1.00 0.00 ATOM 426 N HIS+ 147-9.806-1.131 4.697 1.00 0.00 ATOM 427 H HIS+ 147-10.493-1.000 5.387 1.00 0.00 ATOM 428 CA HIS+ 147-8.399-1.027 5.068 1.00 0.00 ATOM 429 HA HIS+ 147-7.928-0.311 4.410 1.00 0.00 ATOM 430 CB HIS+ 147-8.267-0.550 6.519 1.00 0.00 ATOM 431 1HB HIS+ 147-8.277-1.411 7.173 1.00 0.00 ATOM 432 2HB HIS+ 147-9.107 0.084 6.759 1.00 0.00 ATOM 433 QB HIS+ 147-8.692-0.664 6.966 1.00 0.00 ATOM 434 CG HIS+ 147-7.014 0.224 6.796 1.00 0.00 ATOM 435 ND1 HIS+ 147-6.984 1.600 6.892 1.00 0.00 ATOM 436 CD2 HIS+ 147-5.743-0.193 7.017 1.00 0.00 ATOM 437 1HD HIS+ 147-7.756 2.202 6.775 1.00 0.00 ATOM 438 CE1 HIS+ 147-5.751 1.995 7.159 1.00 0.00 ATOM 439 NE2 HIS+ 147-4.978 0.926 7.242 1.00 0.00 ATOM 440 2HD HIS+ 147-5.391-1.218 7.002 1.00 0.00 ATOM 441 1HE HIS+ 147-5.429 3.019 7.290 1.00 0.00 ATOM 442 2HE HIS+ 147-4.049 0.924 7.561 1.00 0.00 ATOM 443 C HIS+ 147-7.723-2.383 4.901 1.00 0.00 ATOM 444 O HIS+ 147-6.545-2.469 4.562 1.00 0.00 ATOM 445 N LEU 148-8.494-3.442 5.128 1.00 0.00 ATOM 446 H LEU 148-9.429-3.304 5.381 1.00 0.00 ATOM 447 CA LEU 148-7.992-4.802 4.991 1.00 0.00 ATOM 448 HA LEU 148-7.011-4.843 5.442 1.00 0.00 ATOM 449 CB LEU 148-8.920-5.784 5.716 1.00 0.00 ATOM 450 1HB LEU 148-9.937-5.563 5.430 1.00 0.00 ATOM 451 2HB LEU 148-8.820-5.622 6.780 1.00 0.00 ATOM 452 QB LEU 148-9.378-5.593 6.105 1.00 0.00 ATOM 453 CG LEU 148-8.655-7.262 5.430 1.00 0.00 ATOM 454 HG LEU 148-8.182-7.354 4.463 1.00 0.00 ATOM 455 QD1 LEU 148-7.492-7.989 6.715 1.00 0.00 ATOM 456 QD2 LEU 148-10.269-8.226 5.385 1.00 0.00 ATOM 457 CD1 LEU 148-7.714-7.848 6.469 1.00 0.00 ATOM 458 1HD1 LEU 148-6.728-7.956 6.042 1.00 0.00 ATOM 459 2HD1 LEU 148-8.080-8.817 6.779 1.00 0.00 ATOM 460 3HD1 LEU 148-7.667-7.192 7.325 1 : 00 0.00 ATOM 461 CD2 LEU 148-9.960-8.041 5.393 1.00 0.00 ATOM 462 1HD2 LEU 148-10.686-7.558 6.031 1.00 0.00 ATOM 463 2HD2 LEU 148-9.787-9.048 5.745 1.00 0.00 ATOM 464 3HD2 LEU 148-10.333-8.072 4.381 1.00 0.00 ATOM 465 QQD LEU 148-8. 880-8.107 6.050 1.00 0.00 ATOM 466 C LEU 148-7. 875-5.172 3.519 1.00 0.00 ATOM 467 O LEU 148-6.979-5.914 3.127 1.00 0.00 ATOM 468 N HIS+ 149-8.780-4.637 2.709 1.00 0.00 ATOM 469 H HIS+ 149-9.461-4.043 3.082 1.00 0.00 ATOM 470 CA HIS+ 149-8.777-4.900 1.276 1.00 0.00 ATOM 471 HA HIS+ 149-8.815-5.970 1.137 1.00 0.00 ATOM 472 CB HIS+ 149-10.000-4.272 0.619 1.00 0.00 ATOM 473 1HB HIS+ 149-9.725-3.914-0.365 1.00 0.00 ATOM 474 2HB HIS+ 149-10.335-3.439 1.217 1.00 0.00 ATOM 475 QB HIS+ 149-10.030-3.677 0.426 1.00 0.00 ATOM 476 CG HIS+ 149-11.147-5.221 0.458 1.00 0.00 ATOM 477 ND1 HIS+ 149-12.280-5.189 1.248 1.00 0.00 ATOM 478 CD2 HIS+ 149-11.332-6.232-0.420 1.00 0.00 ATOM 479 1HD HIS+ 149-12.458-4.552 1.978 1.00 0.00 ATOM 480 CE1 HIS+ 149-13.108-6.143 0.860 1.00 0.00 ATOM 481 NE2 HIS+ 149-12.557-6.791-0.153 1.00 0.00 ATOM 482 2HD HIS+ 149-10.645-6.535-1.199 1.00 0.00 ATOM 483 1HE HIS+ 149-14.073-6.358 1.295 1.00 0.00 ATOM 484 2HE HIS+ 149-13.034-7.407-0.749 1.00 0.00

ATOM 485 C HIS+ 149-7. 500-4.371 0.638 1.00 0.00 ATOM 486 O HIS+ 149-6.765-5.125 0.005 1.00 0.00 ATOM 487 N TRP 150-7. 221-3.082 0.834 1.00 0.00 ATOM 488 H TRP 150-7. 836-2. 532 1.366 1.00 0.00 ATOM 489 CA TRP 150-6.002-2.477 0.295 1.00 0.00 ATOM 490 HA TRP 150-5.988-2.633-0.774 1.00 0.00 ATOM 491 CB TRP 150-5.935-0.980 0.602 1.00 0.00 ATOM 492 1HB TRP 150-4.972-0.604 0.287 1.00 0.00 ATOM 493 2HB TRP 150-6.032-0.839 1.667 1.00 0.00 ATOM 494 QB TRP 150-5.502-0.722 0.977 1.00 0.00 ATOM 495 CG TRP 150-6. 991-0.151-0.062 1.00 0.00 ATOM 496 CD1 TRP 150-7. 460 1.055 0.370 1.00 0.00 ATOM 497 CD2 TRP 150-7.701-0.446-1.268 1.00 0.00 ATOM 498 CE3 TRP 150-7.682-1.509-2.174 1.00 0.00 ATOM 499 CE2 TRP 150-8. 584 0.623-1.500 1.00 0.00 ATOM 500 NE1 TRP 150-8. 417 1. 524-0. 489 1.00 0.00 ATOM 501 HD TRP 150-7. 118 1.555 1.264 1.00 0.00 ATOM 502 3HE TRP 150-7. 023-2.351-2.034 1.00 0.00 ATOM 503 CZ3 TRP 150-8.527-1.470-3.257 1.00 0.00 ATOM 504 CZ2 TRP 150-9. 432 0.661-2.596 1.00 0.00 ATOM 505 1HE TRP 150-8. 906 2.369-0.393 1.00 0.00 ATOM 506 3HZ TRP 150-8. 534-2.290-3.961 1.00 0.00 ATOM 507 CH2 TRP 150-9.391-0.392-3.461 1.00 0.00 ATOM 508 2HZ TRP 150-10.109 1.488-2.767 1.00 0.00 ATOM 509 HH TRP 150-10. 042-0.409-4.324 1.00 0.00 ATOM 510 C TRP 150-4. 789-3.157 0.884 1.00 0.00 ATOM 511 O TRP 150-3. 779-3.307 0.215 1.00 0.00 ATOM 512 N HIS+ 151-4.909-3.587 2.135 1.00 0.00 ATOM 513 H HIS+ 151-5.756-3.447 2.609 1.00 0.00 ATOM 514 CA HIS+ 151-3.826-4.285 2.807 1.00 0.00 ATOM 515 HA HIS+ 151-2.968-3.632 2.833 1.00 0.00 ATOM 516 CB HIS+ 151-4.248-4.646 4.243 1.00 0.00 ATOM 517 1HB HIS+ 151-5.149-5.244 4.197 1.00 0.00 ATOM 518 2HB HIS+ 151-4.462-3.737 4.782 1.00 0.00 ATOM 519 QB HIS+ 151-4.805-4.491 4.489 1.00 0.00 ATOM 520 CG HIS+ 151-3.231-5.416 5.039 1.00 0.00 ATOM 521 ND1 HIS+ 151-2.851-5.057 6.314 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.544-6.549 4.753 1.00 0.00 ATOM 523 1HD HIS+ 151-3.174-4.274 6.811 1.00 0.00 ATOM 524 CE1 HIS+ 151-1.977-5.935 6. 774 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.774-6.849 5.847 1.00 0.00 ATOM 526 2HD HIS+ 151-2.591-7.108 3.825 1.00 0.00 ATOM 527 1HE HIS+ 151-1.505-5.907 7.746 1.00 0.00 ATOM 528 2HE HIS+ 151-1.271-7.681 5.978 1.00 0.00 ATOM 529 C HIS+ 151-3. 478-5.541 2.019 1.00 0.00 ATOM 530 O HIS+ 151-2.309-5.824 1.771 1.00 0.00 ATOM 531 N THR 152-4. 507-6.280 1.628 1.00 0.00 ATOM 532 H THR 152-5.416-5.993 1.856 1. 00 0.00 ATOM 533 CA THR 152-4.327-7.500 0.863 1.00 0.00 ATOM 534 HA THR 152-3.595-8.104 1.380 1.00 0.00 ATOM 535 CB THR 152-5.644-8.276 0.782 1.00 0.00 ATOM 536 HB THR 152-6.291-7.797 0.058 1.00 0.00 ATOM 537 QG2 THR 152-5.429-10.063 0.264 1.00 0.00 ATOM 538 OG1 THR 152-6.300-8.276 2.041 1.00 0.00 ATOM 539 1HG THR 152-6.620-7.388 2.242 1.00 0.00 ATOM 540 CG2 THR 152-5.470-9.719 0.366 1.00 0.00 ATOM 541 1HG2 THR 152-6. 434-10.144 0.128 1.00 0.00 ATOM 542 2HG2 THR 152-5.021-10.276 1.173 1.00 0.00 ATOM 543 3HG2 THR 152-4.832-9.769-0.508 1.00 0.00 ATOM 544 C THR 152-3.789-7.194-0.528 1.00 0.00 ATOM 545 O THR 152-2.797-7.783-0.934 1.00 0.00 ATOM 546 N VAL 153-4.422-6.258-1.241 1.00 0.00 ATOM 547 H VAL 153-5.202-5.800-0.854 1.00 0.00 ATOM 548 CA VAL 153-3.963-5.886-2.580 1.00 0.00 ATOM 549 HA VAL 153-4.029-6.760-3.206 1.00 0.00 ATOM 550 CB VAL 153-4.838-4.769-3.194 1.00 0.00 ATOM 551 HB VAL 153-4.686-3.865-2.623 1.00 0.00 ATOM 552 QG1 VAL 153-4.341-4.432-4.977 1.00 0.00 ATOM 553 QG2 VAL 153-6.660-5.231-3.097 1.00 0.00 ATOM 554 CG1 VAL 153-4.436-4.495-4.635 1. 00 0. 00 ATOM 555 1HG1 VAL 153-3.540-5.052-4.871 1. 00 0. 00 ATOM 556 2HG1 VAL 153-4.248-3.440-4.763 1.00 0.00

ATOM 557 3HG1 VAL 153-5.234-4.803-5.295 1.00 0.00 ATOM 558 CG2 VAL 153-6.311-5.141-3.116 1.00 0.00 ATOM 559 1HG2 VAL 153-6.662-5.018-2.101 1.00 0.00 ATOM 560 2HG2 VAL 153-6.438-6.172-3.416 1.00 0.00 ATOM 561 3HG2 VAL 153-6.881-4.503-3.773 1.00 0.00 ATOM 562 QQG VAL 153-5.500-4.832-4.037 1.00 0.00 ATOM 563 C VAL 153-2.512-5.434-2.532 1.00 0.00 ATOM 564 0 VAL 153-1.686-5.860-3.338 1.00 0.00 ATOM 565 N ALA 154-2.210-4.588-1.563 1.00 0.00 ATOM 566 H ALA 154-2.922-4.301-0.941 1.00 0.00 ATOM 567 CA ALA 154-0.858-4.087-1.371 1.00 0.00 ATOM 568 HA ALA 154-0.546-3.575-2.269 1.00 0.00 ATOM 569 QB ALA 154-0.835-2.871 0.055 1.00 0.00 ATOM 570 CB ALA 154-0.840-3.104-0.218 1.00 0.00 ATOM 571 1HB ALA 154-0.261-2.235-0.497 1.00 0.00 ATOM 572 2HB ALA 154-0.393-3.572 0.647 1.00 0.00 ATOM 573 3HB ALA 154-1.851-2.804 0.016 1.00 0.00 ATOM 574 C ALA 154 0.102-5.231-1.085 1.00 0.00 ATOM 575 O ALA 154 1.136-5.375-1.741 1.00 0.00 ATOM 576 N LYS+ 155-0.255-6.043-0.097 1.00 0.00 ATOM 577 H LYS+ 155-1.097-5.867 0.380 1.00 0.00 ATOM 578 CA LYS+ 155 0.555-7.185 0.297 1.00 0.00 ATOM 579 HA LYS+ 155 1.523-6.817 0.619 1.00 0.00 ATOM 580 CB LYS+ 155-0.120-7.932 1.455 1.00 0.00 ATOM 581 1HB LYS+ 155-1.140-8.152 1.171 1.00 0.00 ATOM 582 2HB LYS+ 155-0.134-7.289 2.321 1.00 0.00 ATOM 583 QB LYS+ 155-0.637-7.721 1.746 1.00 0.00 ATOM 584 CG LYS+ 155 0.556-9.239 1.843 1.00 0.00 ATOM 585 1HG LYS+ 155 1.117-9.085 2.754 1.00 0.00 ATOM 586 2HG LYS+ 155 1.226-9.538 1.051 1.00 0.00 ATOM 587 QG LYS+ 155 1.172-9.312 1.902 1.00 0.00 ATOM 588 CD LYS+ 155-0.468-10.343 2.073 1.00 0.00 ATOM 589 1HD LYS+ 155-1.447-9.896 2.187 1.00 0.00 ATOM 590 2HD LYS+ 155-0.210-10.878 2.975 1.00 0.00 ATOM 591 QD LYS+ 155-0.828-10.387 2.581 1.00 0.00 ATOM 592 CE LYS+ 155-0.509-11.327 0.913 1.00 0.00 ATOM 593 1HE LYS+ 155-0.628-10.773-0.009 1.00 0.00 ATOM 594 2HE LYS+ 155-1.355-11.987 1.045 1.00 0.00 ATOM 595 QE LYS+ 155-0.991-11.380 0.518 1.00 0.00 ATOM 596 NZ LYS+ 155 0.736-12.142 0.836 1.00 0.00 ATOM 597 1HZ LYS+ 155 0.593-12.952 0.200 1.00 0.00 ATOM 598 2HZ LYS+ 155 0.996-12.496 1.778 1.00 0.00 ATOM 599 3HZ LYS+ 155 1.527-11.561 0.465 1.00 0.00 ATOM 600 QZ LYS+ 155 1.039-12.337 0. 814 1.00 0.00 ATOM 601 C LYS+ 155 0.758-8.120-0.880 1.00 0.00 ATOM 602 O LYS+ 155 1.883-8.510-1.163 1.00 0.00 ATOM 603 N GLU 156-0.331-8.474-1.553 1.00 0.00 ATOM 604 H GLU 156-1.209-8.124-1.268 1.00 0.00 ATOM 605 CA GLU 156-0.270-9.367-2.701 1.00 0.00 ATOM 606 HA GLU 156 0.109-10.316-2.354 1.00 0.00 ATOM 607 CB GLU 156-1.661-9.582-3.287 1.00 0.00 ATOM 608 1HB GLU 156-1.566-9.906-4.313 1.00 0.00 ATOM 609 2HB GLU 156-2.202-8.647-3.261 1.00 0.00 ATOM 610 QB GLU 156-1.884-9.277-3.787 1.00 0.00 ATOM 611 CG GLU 156-2.471-10.622-2.530 1.00 0.00 ATOM 612 1HG GLU 156-2.270-10.522-1.475 1.00 0.00 ATOM 613 2HG GLU 156-2.173-11.604-2.862 1.00 0.00 ATOM 614 QG GLU 156-2.221-11.063-2.169 1.00 0.00 ATOM 615 CD GLU 156-3.959-10.472-2.753 1.00 0.00 ATOM 616 OE1 GLU 156-4.694-11.441-2.482 1.00 0.00 ATOM 617 OE2 GLU 156-4.387-9.385-3.190 1.00 0.00 ATOM 618 C GLU 156 0.681-8.834-3.762 1.00 0.00 ATOM 619 O GLU 156 1.528-9.573-4.240 1.00 0.00 ATOM 620 N THR 157 0.555-7.555-4.107 1.00 0.00 ATOM 621 H THR 157-0.141-7.008-3.676 1.00 0.00 ATOM 622 CA THR 157 1.437-6.941-5.104 1.00 0.00 ATOM 623 HA THR 157 1.254-7.431-6.050 1.00 0.00 ATOM 624 CB THR 157 1.120-5.446-5.249 1.00 0.00 ATOM 625 HB THR 157 1.378-4.941-4.328 1.00 0.00 ATOM 626 QG2 THR 157 2.051-4.609-6.646 1.00 0.00 ATOM 627 OG1 THR 157-0.260-5.250-5.495 1.00 0.00 ATOM 628 1HG THR 157-0.770-5.528-4.722 1.00 0.00

ATOM 629 CG2 THR 157 1.873-4.769-6.377 1.00 0.00 ATOM 630 1HG2 THR 157 1.622-3.719-6.399 1.00 0.00 ATOM 631 2HG2 THR 157 1.595-5.225-7.316 1.00 0.00 ATOM 632 3HG2 THR 157 2.935-4.883-6.222 1.00 0.00 ATOM 633 C THR 157 2.912-7.143-4.728 1.00 0.00 ATOM 634 0 THR 157 3.750-7.423-5.584 1.00 0.00 ATOM 635 N CYS 158 3.224-7.007-3.444 1.00 0.00 ATOM 636 H CYS 158 2.515-6.781-2.797 1.00 0.00 ATOM 637 CA CYS 158 4.594-7.181-2.969 1.00 0.00 ATOM 638 HA CYS 158 5.253-6.725-3.693 1.00 0.00 ATOM 639 CB CYS 158 4.767-6.463-1.635 1.00 0.00 ATOM 640 1HB CYS 158 5.662-6.809-1.155 1.00 0.00 ATOM 641 2HB CYS 158 3.922-6.692-1.008 1.00 0.00 ATOM 642 QB CYS 158 4.792-6.751-1.082 1.00 0.00 ATOM 643 SG CYS 158 4.870-4.645-1.792 1.00 0.00 ATOM 644 C CYS 158 4.970-8.665-2.852 1.00 0.00 ATOM 645 O CYS 158 6.046-9.066-3.295 1.00 0.00 ATOM 646 N SER 159 4.089-9.477-2.259 1.00 0.00 ATOM 647 H SER 159 3.249-9.103-1.920 1.00 0.00 ATOM 648 CA SER 159 4.345-10.915-2.099 1.00 0.00 ATOM 649 HA SER 159 5.312-11.026-1.630 1.00 0.00 ATOM 650 CB SER 159 3.287-11.577-1.214 1.00 0.00 ATOM 651 1HB SER 159 3.711-12.463-0.760 1.00 0.00 ATOM 652 2HB SER 159 2.444-11.859-1.826 1.00 0.00 ATOM 653 QB SER 159 3.078-12.161-1.293 1.00 0.00 ATOM 654 OG SER 159 2.835-10.707-0.186 1.00 0.00 ATOM 655 HG SER 159 2.663-9.831-0.561 1.00 0.00 ATOM 656 C SER 159 4.378-11.632-3.449 1.00 0.00 ATOM 657 O SER 159 4.972-12.699-3.568 1.00 0.00 ATOM 658 N GLU 160 3.742-11.037-4.460 1.00 0.00 ATOM 659 H GLU 160 3.285-10.184-4.302 1.00 0.00 ATOM 660 CA GLU 160 3.715-11.613-5.801 1.00 0.00 ATOM 661 HA GLU 160 3.358-12.630-5.728 1.00 0.00 ATOM 662 CB GLU 160 2.781-10.803-6.712 1.00 0.00 ATOM 663 1HB GLU 160 3.254-9.857-6.939 1.00 0.00 ATOM 664 2HB GLU 160 1.859-10.613-6.184 1.00 0.00 ATOM 665 QB GLU 160 2.557-10.235-6.562 1.00 0.00 ATOM 666 CG GLU 160 2.442-11.486-8.028 1.00 0.00 ATOM 667 1HG GLU 160 1.378-11.406-8.199 1.00 0.00 ATOM 668 2HG GLU 160 2.720-12.528-7.965 1.00 0.00 ATOM 669 QG GLU 160 2.049-11.967-8.082 1.00 0.00 ATOM 670 CD GLU 160 3.169-10.860-9.198 1.00 0.00 ATOM 671 OEl GLU 160 3.635-9.708-9.059 1.00 0.00 ATOM 672 OE2 GLU 160 3.313-11.524-10.241 1.00 0.00 ATOM 673 C GLU 160 5.129-11.618-6.366 1.00 0.00 ATOM 674 O GLU 160 5.480-12.408-7.245 1.00 0.00 ATOM 675 N LYS+ 161 5.946-10.731-5.830 1.00 0.00 ATOM 676 H LYS+ 161 5.612-10.143-5.122 1.00 0.00 ATOM 677 CA LYS+ 161 7.324-10.625-6.233 1.00 0.00 ATOM 678 HA LYS+ 161 7.461-11.221-7.124 1.00 0.00 ATOM 679 CB LYS+ 161 7.680-9.164-6.530 1.00 0.00 ATOM 680 1HB LYS+ 161 8.080-8.717-5.632 1.00 0.00 ATOM 681 2HB LYS+ 161 6.780-8.638-6.809 1.00 0.00 ATOM 682 QB LYS+ 161 7.430-8.678-6.221 1.00 0.00 ATOM 683 CG LYS+ 161 8.706-8.993-7.645 1.00 0.00 ATOM 684 1HG LYS+ 161 9.686-9.233-7.256 1.00 0.00 ATOM 685 2HG LYS+ 161 8.693-7.967-7.979 1.00 0.00 ATOM 686 QG LYS+ 161 9.190-8.600-7.618 1.00 0.00 ATOM 687 CD LYS+ 161 8.411-9.903-8.836 1.00 0.00 ATOM 688 1HD LYS+ 161 8.367-10.926-8.491 1.00 0.00 ATOM 689 2HD LYS+ 161 9.210-9.801-9.559 1.00 0.00 ATOM 690 QD LYS+ 161 8.789-10.364-9.025 1.00 0.00 ATOM 691 CE LYS+ 161 7.090-9.547-9.513 1.00 0.00 ATOM 692 1HE LYS+ 161 7.282-9.335-10.556 1.00 0.00 ATOM 693 2HE LYS+ 161 6.682-8.666-9.037 1.00 0.00 ATOM 694 QE LYS+ 161 6.982-9.001-9.797 1.00 0.00 ATOM 695 NZ LYS+ 161 6.091-10.647-9.417 1.00 0.00 ATOM 696 1HZ LYS+ 161 6.231-11.202-8.547 1.00 0.00 ATOM 697 2HZ LYS+ 161 6. 163-11.283-10.233 1.00 0.00 ATOM 698 3HZ LYS+ 161 5.116-10.247-9.396 1.00 0.00 ATOM 699 QZ LYS+ 161 5.837-10.911-9.392 1.00 0.00 ATOM 700 C LYS+ 161 8.191-11.192-5.119 1.00 0.00

ATOM 701 O LYS+ 161 7.856-12.214-4.529 1.00 0.00 ATOM 702 N SER 162 9.294-10.538-4.828 1.00 0.00 ATOM 703 H SER 162 9.521-9.731-5.323 1.00 0.00 ATOM 704 CA SER 162 10.177-11.003-3.781 1.00 0.00 ATOM 705 HA SER 162 9.805-11.954-3.435 1.00 0.00 ATOM 706 CB SER 162 11.590-11.198-4.334 1.00 0.00 ATOM 707 1HB SER 162 11.921-12.204-4.117 1.00 0.00 ATOM 708 2HB SER 162 12.258-10.492-3.861 1.00 0.00 ATOM 709 QB SER 162 12.090-11.348-3.989 1.00 0.00 ATOM 710 OG SER 162 11.622-10.994-5.743 1.00 0.00 ATOM 711 HG SER 162 12.172-11.672-6.147 1.00 0.00 ATOM 712 C SER 162 10.201-10.029-2. 608 1.00 0.00 ATOM 713 O SER 162 11.271-9.645-2.146 1.00 0.00 ATOM 714 N THR 163 9.027-9.617-2.123 1.00 0.00 ATOM 715 H THR 163 8.188-9.939-2.525 1.00 0.00 ATOM 716 CA THR 163 8.976-8.691-0.994 1.00 0.00 ATOM 717 HA THR 163 9.885-8.828-0.422 1.00 0.00 ATOM 718 CB THR 163 8.914-7.237-1.462 1.00 0.00 ATOM 719 HB THR 163 8.789-6.612-0.583 1.00 0.00 ATOM 720 QG2 THR 163 10.448-6.648-2.363 1.00 0.00 ATOM 721 OG1 THR 163 7.812-7.029-2.325 1.00 0.00 ATOM 722 1HG THR 163 7.522-7.877-2.690 1.00 0.00 ATOM 723 CG2 THR 163 10.153-6.760-2.190 1.00 0.00 ATOM 724 1HG2 THR 163 10.823-7.595-2.344 1.00 0.00 ATOM 725 2HG2 THR 163 10.650-6.005-1.598 1.00 0.00 ATOM 726 3HG2 THR 163 9.872-6.342-3.145 1.00 0.00 ATOM 727 C THR 163 7.786-8.969-0.077 1.00 0.00 ATOM 728 O THR 163 6.785-9.558-0.481 1.00 0.00 ATOM 729 N ASN 164 7.907-8.515 1.162 1.00 0.00 ATOM 730 H ASN 164 8.736-8.043 1.411 1.00 0.00 ATOM 731 CA ASN 164 6.851-8.679 2.166 1.00 0.00 ATOM 732 HA ASN 164 5.995-9.133 1.677 1.00 0.00 ATOM 733 CB ASN 164 7.327-9.584 3.313 1.00 0.00 ATOM 734 1HB ASN 164 7.138-10.613 3.047 1.00 0.00 ATOM 735 2HB ASN 164 6.774-9.342 4.208 1.00 0.00 ATOM 736 QB ASN 164 6.956-9.978 3.627 1.00 0.00 ATOM 737 CG ASN 164 8.810-9.431 3.611 1.00 0.00 ATOM 738 OD1 ASN 164 9.481-10.391 3.967 1.00 0.00 ATOM 739 ND2 ASN 164 9.322-8.213 3.487 1.00 0.00 ATOM 740 1HD2 ASN 164 8.718-7.485 3.233 1.00 0.00 ATOM 741 2HD2 ASN 164 10.284-8.100 3.600 1.00 0.00 ATOM 742 QD2 ASN 164 9.501-7.793 3.416 1.00 0.00 ATOM 743 C ASN 164 6.444-7.319 2.732 1.00 0.00 ATOM 744 O ASN 164 7.302-6.491 3.028 1.00 0.00 ATOM 745 N LEU 165 5.144-7.085 2.877 1.00 0.00 ATOM 746 H LEU 165 4.502-7.780 2.624 1.00 0.00 ATOM 747 CA LEU 165 4.648-5.809 3.404 1.00 0.00 ATOM 748 HA LEU 165 5.142-5.007 2.875 1.00 0.00 ATOM 749 CB LEU 165 3.137-5.686 3.195 1.00 0.00 ATOM 750 1HB LEU 165 2.673-5.535 4.158 1.00 0.00 ATOM 751 2HB LEU 165 2.771-6.611 2.776 1.00 0.00 ATOM 752 QB LEU 165 2.722-6.073 3.467 1.00 0.00 ATOM 753 CG LEU 165 2.697-4.547 2. 294 1.00 0.00 ATOM 754 HG LEU 165 3.233-3.648 2.563 1.00 0.00 ATOM 755 QD1 LEU 165 3.088-4.951 0.511 1.00 0.00 ATOM 756 QD2 LEU 165 0.859-4.224 2.511 1.00 0.00 ATOM 757 CD1 LEU 165 3.014-4.874 0.856 1.00 0.00 ATOM 758 1HD1 LEU 165 3.803-4.226 0.504 1.00 0.00 ATOM 759 2HD1 LEU 165 2.130-4.724 0.250 1.00 0.00 ATOM 760 3HD1 LEU 165 3.330-5.902 0.781 1.00 0.00 ATOM 761 CD2 LEU 165 1.212-4.286 2.470 1.00 0.00 ATOM 762 1HD2 LEU 165 0.650-5.123 2.082 1.00 0.00 ATOM 763 2HD2 LEU 165 0.938-3.389 1.933 1. 00 0. 00 ATOM 764 3HD2 LEU 165 0.990-4.159 3.520 1. 00 0. 00 ATOM 765 QQD LEU 165 1.974-4.587 1.511 1. 00 0. 00 ATOM 766 C LEU 165 4.947-5.662 4.884 1.00 0.00 ATOM 767 O LEU 165 4.627-6.540 5.682 1.00 0.00 ATOM 768 N HIS+ 166 5.545-4.539 5.236 1. oo o. oo ATOM 769 H HIS+ 166 5.765-3.876 4.546 1. 00 0. oo ATOM 770 CA HIS+ 166 5.875-4.249 6.617 1.00 0.00 ATOM 771 HA HIS+ 166 5.569-5.094 7. 217 1.00 0.00 ATOM 772 CB HIS+ 166 7.390-4.052 6. 763 1.00 0.00

ATOM 773 1HB HIS+ 166 7.695-3.219 6.145 1.00 0.00 ATOM 774 2HB HIS+ 166 7.895-4.944 6.429 1.00 0.00 ATOM 775 QB HIS+ 166 7.795-4.082 6.287 1.00 0.00 ATOM 776 CG HIS+ 166 7.837-3.770 8.162 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.812-4.706 9.173 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.319-2.637 8.712 1.00 0.00 ATOM 779 1HD HIS+ 166 7.504-5.634 9.090 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.260-4.153 10.288 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.575-2.893 10.033 1.00 0.00 ATOM 782 2HD HIS+ 166 8.455-1.687 8.203 1.00 0.00 ATOM 783 1HE HIS+ 166 8.355-4.646 11.244 1.00 0.00 ATOM 784 2HE HIS+ 166 8.725-2. 205 10.715 1.00 0.00 ATOM 785 C HIS+ 166 5.117-3.006 7.092 1.00 0.00 ATOM 786 O HIS+ 166 4.491-3.021 8.153 1.00 0.00 ATOM 787 N ASP 167 5.175-1.933 6.299 1.00 0.00 ATOM 788 H ASP 167 5.689-1.982 5.464 1.00 0.00 ATOM 789 CA ASP 167 4.496-0.680 6.657 1.00 0.00 ATOM 790 HA ASP 167 3.994-0.841 7.599 1.00 0.00 ATOM 791 CB ASP 167 5.502 0.467 6. 829 1.00 0.00 ATOM 792 1HB ASP 167 5. 101 1.180 7.534 1.00 0.00 ATOM 793 2HB ASP 167 5.641 0.955 5.877 1.00 0.00 ATOM 794 QB ASP 167 5.371 1.067 6.705 1.00 0.00 ATOM 795 CG ASP 167 6.858 0.014 7.328 1.00 0.00 ATOM 796 OD1 ASP 167 7.675-0.452 6.502 1.00 0.00 ATOM 797 OD2 ASP 167 7.111 0.132 8.545 1.00 0.00 ATOM 798 C ASP 167 3.455-0.273 5.612 1.00 0.00 ATOM 799 O ASP 167 3.754 0.453 4.669 1.00 0.00 ATOM 800 N TYR 168 2.232-0.739 5.795 1.00 0.00 ATOM 801 H TYR 168 2.058-1.308 6.574 1.00 0.00 ATOM 802 CA TYR 168 1.121-0.423 4.890 1.00 0.00 ATOM 803 HA TYR 168 1.529-0.189 3.908 1.00 0.00 ATOM 804 CB TYR 168 0.197-1.638 4.775 1.00 0.00 ATOM 805 1HB TYR 168 0.513-2.247 3.943 1.00 0.00 ATOM 806 2HB TYR 168-0.815-1.299 4.607 1.00 0.00 ATOM 807 QB TYR 168-0.151-1.773 4.275 1.00 0.00 ATOM 808 QD TYR 168 0.207-2.597 6.166 1.00 0.00 ATOM 809 QE TYR 168 0.246-3.974 8.199 1.00 0.00 ATOM 810 QR TYR 168 0.226-3.285 7.182 1.00 0.00 ATOM 811 CG TYR 168 0.203-2.499 6.021 1.00 0.00 ATOM 812 CD1 TYR 168-0.598-2.184 7.112 1.00 0.00 ATOM 813 1HD TYR 168-1.243-1.320 7.058 1.00 0.00 ATOM 814 CE1 TYR 168-0.578-2.955 8.256 1.00 0.00 ATOM 815 1HE TYR 168-1.207-2.694 9.094 1.00 0.00 ATOM 816 CZ TYR 168 0.247-4.057 8.322 1.00 0.00 ATOM 817 CE2 TYR 168 1.050-4.391 7.253 1.00 0.00 ATOM 818 2HE TYR 168 1.699-5.253 7.305 1.00 0.00 ATOM 819 CD2 TYR 168 1.027-3.614 6.113 1.00 0.00 ATOM 820 2HD TYR 168 1.656-3.873 5.274 1.00 0. 00 ATOM 821 OH TYR 168 0.267-4.829 9.457 1.00 0.00 ATOM 822 HH TYR 168 1.061-4.634 9.964 1.00 0.00 ATOM 823 C TYR 168 0.330 0.783 5.388 1.00 0.00 ATOM 824 O TYR 168 0.145 0.966 6.591 1.00 0.00 ATOM 825 N GLY 169-0.156 1.583 4.456 1.00 0.00 ATOM 826 H GLY 169 0.010 1.375 3.510 1.00 0.00 ATOM 827 CA GLY 169-0.940 2.749 4.798 1.00 0.00 ATOM 828 1HA GLY 169-0.296 3.616 4.822 1.00 0.00 ATOM 829 2HA GLY 169-1.382 2.606 5.774 1.00 0.00 ATOM 830 QA GLY 169-0.839 3.111 5.298 1.00 0.00 ATOM 831 C GLY 169-2.030 2.974 3.782 1.00 0.00 ATOM 832 O GLY 169-1.863 2.630 2.620 1.00 0.00 ATOM 833 N MET 170-3.146 3.532 4.204 1.00 0.00 ATOM 834 H MET 170-3.232 3.784 5.146 1.00 0.00 ATOM 835 CA MET 170-4.259 3.782 3.295 1. 00 0. 00 ATOM 836 HA MET 170-3.967 3.457 2.296 1. 00 0. 00 ATOM 837 CB MET 170-5.507 3.012 3.751 1.00 0.00 ATOM 838 1HB MET 170-6. 380 3.592 3.482 1. 00 0. 00 ATOM 839 2HB MET 170-5.477 2.916 4.825 1. 00 0. 00 ATOM 840 QB MET 170-5.928 3.254 4.153 1.00 0. 00 ATOM 841 CG MET 170-5.669 1.616 3.161 1.00 0. 00 ATOM 842 1HG MET 170-6.245 1.696 2.250 1. 00 0.00 ATOM 843 2HG MET 170-6.210 1.006 3.868 1.00 0. 00 ATOM 844 QG MET 170-6.227 1.351 3.059 1. 00 0.00

ATOM 845 SD MET 170-4.109 0.798 2.781 1.00 0.00 ATOM 846 QE MET 170-4.056-0.740 4.280 1.00 0.00 ATOM 847 CE MET 170-4.065-0.482 4.029 1.00 0.00 ATOM 848 1HE MET 170-3.038-0.721 4.263 1.00 0.00 ATOM 849 2HE MET 170-4.565-1.365 3.658 1.00 0.00 ATOM 850 3HE MET 170-4.565-0.132 4.920 1.00 0.00 ATOM 851 C MET 170-4.571 5.270 3.271 1.00 0. 00 ATOM 852 O MET 170-4.894 5.858 4.303 1.00 0.00 ATOM 853 N LEU 171-4.475 5.876 2.101 1.00 0.00 ATOM 854 H LEU 171-4.215 5.356 1.312 1.00 0.00 ATOM 855 CA LEU 171-4.747 7.299 1.966 1.00 0.00 ATOM 856 HA LEU 171-4.899 7.696 2.959 1.00 0.00 ATOM 857 CB LEU 171-3.547 8.012 1.328 1.00 0.00 ATOM 858 1HB LEU 171-2.686 7.853 1.961 1.00 0.00 ATOM 859 2HB LEU 171-3.759 9.069 1. 299 1.00 0.00 ATOM 860 QB LEU 171-3.222 8.461 1.630 1.00 0.00 ATOM 861 CG LEU 171-3. 186 7.558-0.089 1.00 0.00 ATOM 862 HG LEU 171-3.999 6.974-0.490 1.00 0.00 ATOM 863 QD1 LEU 171-2. 923 9.037-1.211 1.00 0.00 ATOM 864 QD2 LEU 171-1. 643 6.482-0.072 1.00 0.00 ATOM 865 CD1 LEU 171-2.975 8.753-0.995 1.00 0.00 ATOM 866 1HD1 LEU 171-2.236 8.509-1.747 1.00 0.00 ATOM 867 2HD1 LEU 171-2.627 9.591-0.410 1.00 0.00 ATOM 868 3HD1 LEU 171-3.906 9.011-1.476 1.00 0.00 ATOM 869 CD2 LEU 171-1.940 6.688-0.075 1.00 0.00 ATOM 870 1HD2 LEU 171-1.419 6.819 0.864 1.00 0.00 ATOM 871 2HD2 LEU 171-1.289 6.977-0.890 1.00 0.00 ATOM 872 3HD2 LEU 171-2.221 5.652-0.189 1.00 0.00 ATOM 873 QQD LEU 171-2.283 7.760-0.642 1.00 0.00 ATOM 874 C LEU 171-6. 010 7.537 1.147 1.00 0.00 ATOM 875 O LEU 171-6.748 6.593 0.855 1.00 0.00 ATOM 876 N LEU 172-6.244 8.804 0.784 1.00 0.00 ATOM 877 H LEU 172-5.603 9.492 1.059 1.00 0.00 ATOM 878 CA LEU 172-7.415 9.211-0.009 1.00 0.00 ATOM 879 HA LEU 172-7.532 10.278 0.104 1.00 0.00 ATOM 880 CB LEU 172-7.194 8.897-1.494 1.00 0.00 ATOM 881 1HB LEU 172-8.054 8.349-1.850 1.00 0.00 ATOM 882 2HB LEU 172-6.326 8.260-1.582 1.00 0.00 ATOM 883 QB LEU 172-7.190 8.304-1.716 1.00 0.00 ATOM 884 CG LEU 172-6.996 10.115-2.400 1.00 0.00 ATOM 885 HG LEU 172-7.882 10.732-2.364 1.00 0.00 ATOM 886 QD1 LEU 172-5.541 11.153-1.821 1.00 0.00 ATOM 887 QD2 LEU 172-6.738 9.572-4.182 1.00 0.00 ATOM 888 CD1 LEU 172-5.820 10.954-1.930 1.00 0.00 ATOM 889 1HD1 LEU 172-6.145 11.971-1.768 1.00 0.00 ATOM 890 2HD1 LEU 172-5.045 10.941-2.684 1.00 0.00 ATOM 891 3HD1 LEU 172-5.432 10.548-1.009 1.00 0.00 ATOM 892 CD2 LEU 172-6.788 9.676-3.839 1.00 0.00 ATOM 893 1HD2 LEU 172-7.384 10.294-4.494 1.00 0.00 ATOM 894 2HD2 LEU 172-7.085 8.643-3.950 1.00 0.00 ATOM 895 3HD2 LEU 172-5.744 9.780-4.100 1.00 0.00 ATOM 896 QQD LEU 172-6. 139 10.363-3.001 1.00 0.00 ATOM 897 C LEU 172-8.696 8.529 0.470 1.00 0.00 ATOM 898 O LEU 172-9.255 7.691-0.238 1.00 0.00 ATOM 899 N PRO 173-9.180 8.872 1.677 1.00 0.00 ATOM 900 CD PRO 173-8.585 9.863 2.596 1.00 0.00 ATOM 901 CA PRO 173-10.397 8.272 2.234 1.00 0.00 ATOM 902 HA PRO 173-10.238 7.232 2.485 1.00 0.00 ATOM 903 CB PRO 173-10.646 9.076 3.512 1.00 0.00 ATOM 904 1HB PRO 173-11.039 8.424 4.279 1.00 0.00 ATOM 905 2HB PRO 173-11.353 9.868 3.310 1.00 0.00 ATOM 906 QB PRO 173-11.196 9.146 3.794 1.00 0.00 ATOM 907 CG PRO 173-9.310 9.617 3.889 1.00 0.00 ATOM 908 1HG PRO 173-8.775 8.894 4. 488 1.00 0.00 ATOM 909 2HG PRO 173-9.429 10.542 4.435 1.00 0.00 ATOM 910 QG PRO 173-9.102 9.718 4.461 1.00 0.00 ATOM 911 1HD PRO 173-7.526 9.689 2.718 1.00 0.00 ATOM 912 2HD PRO 173-8.766 10.870 2.247 1.00 0.00 ATOM 913 QD PRO 173-8.146 10.279 2.482 1.00 0.00 ATOM 914 C PRO 173-11.592 8.383 1.292 1.00 0.00 ATOM 915 O PRO 173-11.793 9.407 0.635 1.00 0.00 ATOM 916 N CYS 174-12.380 7.323 1.235 1.00 0.00

ATOM 917 H CYS 174-12.166 6. 541 1.790 1.00 0.00 ATOM 918 CA CYS 174-13.562 7.288 0.387 1.00 0.00 ATOM 919 HA CYS 174-13.595 8.207-0.179 1.00 0.00 ATOM 920 CB CYS 174-13. 503 6.103-0.578 1.00 0.00 ATOM 921 1HB CYS 174-13.883 5.224-0.079 1.00 0.00 ATOM 922 2HB CYS 174-12.476 5.932-0.865 1.00 0.00 ATOM 923 QB CYS 174-13.179 5.578-0.472 1.00 0.00 ATOM 924 SG CYS 174-14.473 6.339-2.103 1.00 0.00 ATOM 925 C CYS 174-14. 809 7.199 1.251 1.00 0.00 ATOM 926 O CYS 174-15.848 7.766 0.930 1.00 0.00 ATOM 927 N GLY 175-14.683 6. 494 2.363 1.00 0.00 ATOM 928 H GLY 175-13.818 6. 076 2.573 1.00 0.00 ATOM 929 CA GLY 175-15.785 6.349 3.285 1.00 0.00 ATOM 930 1HA GLY 175-16.307 5.428 3.073 1.00 0.00 ATOM 931 2HA GLY 175-16.464 7.181 3.159 1.00 0.00 ATOM 932 QA GLY 175-16.385 6.304 3.116 1.00 0.00 ATOM 933 C GLY 175-15.289 6.321 4.709 1.00 0.00 ATOM 934 O GLY 175-14.109 6.560 4.952 1.00 0.00 ATOM 935 N ILE 176-16. 173 6.019 5.649 1.00 0.00 ATOM 936 H ILE 176-17.099 5.828 5.395 1.00 0.00 ATOM 937 CA ILE 176-15.793 5.952 7.056 1.00 0.00 ATOM 938 HA ILE 176-15.260 6.861 7.297 1.00 0.00 ATOM 939 CB ILE 176-17.048 5.866 7.964 1.00 0.00 ATOM 940 HB ILE 176-17.659 6.734 7.765 1.00 0.00 ATOM 941 QG2 ILE 176-18.073 4.339 7.558 1.00 0.00 ATOM 942 CG2 ILE 176-17.877 4.631 7.633 1.00 0.00 ATOM 943 1HG2 ILE 176-17.219 3.811 7.387 1.00 0.00 ATOM 944 2HG2 ILE 176-18.523 4.842 6.795 1.00 0.00 ATOM 945 3HG2 ILE 176-18.477 4.364 8.492 1.00 0.00 ATOM 946 CG1 ILE 176-16.657 5.870 9.446 1.00 0.00 ATOM 947 1HG1 ILE 176-16.244 6.836 9.699 1.00 0.00 ATOM 948 2HG1 ILE 176-15.909 5.109 9.615 1.00 0.00 ATOM 949 QG1 ILE 176-16.076 5.972 9.657 1.00 0.00 ATOM 950 QD1 ILE 176-18.091 5.533 10.605 1.00 0.00 ATOM 951 CD1 ILE 176-17. 815 5.598 10.383 1.00 0.00 ATOM 952 1HD1 ILE 176-17.458 5.065 11.251 1.00 0.00 ATOM 953 2HD1 ILE 176-18.557 5.000 9.874 1.00 0.00 ATOM 954 3HD1 ILE 176-18.257 6.534 10.691 1.00 0.00 ATOM 955 C ILE 176-14.862 4.755 7.307 1.00 0.00 ATOM 956 O ILE 176-14. 104 4.728 8.275 1.00 0.00 ATOM 957 N ASP 177-14. 934 3.773 6.412 1.00 0.00 ATOM 958 H ASP 177-15.557 3.864 5.667 1.00 0.00 ATOM 959 CA ASP 177-14.119 2.564 6.505 1.00 0.00 ATOM 960 HA ASP 177-13.314 2.750 7.202 1.00 0.00 ATOM 961 CB ASP 177-15.005 1.421 7.042 1.00 0.00 ATOM 962 1HB ASP 177-15. 937 1.417 6.498 1.00 0.00 ATOM 963 2HB ASP 177-15.212 1.606 8.085 1.00 0.00 ATOM 964 QB ASP 177-15.574 1.511 7.291 1.00 0.00 ATOM 965 CG ASP 177-14.384 0.046 6.933 1.00 0.00 ATOM 966 OD1 ASP 177-13. 294-0.167 7.495 1.00 0.00 ATOM 967 OD2 ASP 177-14. 993-0. 820 6.268 1.00 0.00 ATOM 968 C ASP 177-13.524 2.223 5.125 1.00 0.00 ATOM 969 O ASP 177-12.942 1.161 4.905 1.00 0.00 ATOM 970 N LYS+ 178-13.675 3.139 4.178 1.00 0.00 ATOM 971 H LYS+ 178-14.138 3.976 4.387 1.00 0.00 ATOM 972 CA LYS+ 178-13.159 2.916 2.829 1.00 0.00 ATOM 973 HA LYS+ 178-12.665 1.956 2.821 1.00 0.00 ATOM 974 CB LYS+ 178-14.302 2.895 1.810 1.00 0.00 ATOM 975 1HB LYS+ 178-13.932 2.479 0.884 1.00 0.00 ATOM 976 2HB LYS+ 178-14.625 3.910 1.631 1.00 0.00 ATOM 977 QB LYS+ 178-14. 278 3.194 1.257 1.00 0.00 ATOM 978 CG LYS+ 178-15.511 2.080 2.257 1.00 0.00 ATOM 979 1HG LYS+ 178-16.409 2.553 1.885 1.00 0.00 ATOM 980 2HG LYS+ 178-15.534 2.057 3.336 1.00 0.00 ATOM 981 QG LYS+ 178-15.971 2.305 2.610 1.00 0.00 ATOM 982 CD LYS+ 178-15.452 0.650 1.736 1.00 0.00 ATOM 983 1HD LYS+ 178-14.672 0.582 0.989 1.00 0.00 ATOM 984 2HD LYS+ 178-16. 403 0.401 1.286 1.00 0.00 ATOM 985 QD LYS+ 178-15.537 0.491 1.137 1.00 0.00 ATOM 986 CE LYS+ 178-15.157-0.346 2.851 1.00 0.00 ATOM 987 1HE LYS+ 178-14.146-0.185 3.200 1. 00 0. 00 ATOM 988 2HE LYS+ 178-15.243-1.347 2.454 1. 00 0. 00

ATOM 989 QE LYS+ 178-14.694-0.766 2.827 1.00 0.00 ATOM 990 NZ LYS+ 178-16.094-0.198 3.999 1.00 0.00 ATOM 991 1HZ LYS+ 178-15.586-0.394 4.904 1.00 0.00 ATOM 992 2HZ LYS+ 178-16.881-0.869 3.913 1.00 0.00 ATOM 993 3HZ LYS+ 178-16.473 0.764 4.036 1.00 0.00 ATOM 994 QZ LYS+ 178-16.313-0.167 4.284 1.00 0.00 ATOM 995 C LYS+ 178-12.142 3.968 2.434 1.00 0.00 ATOM 996 O LYS+ 178-12.240 5.125 2.830 1.00 0.00 ATOM 997 N PHE 179-11.170 3.552 1.636 1.00 0.00 ATOM 998 H PHE 179-11.156 2.614 1.345 1.00 0.00 ATOM 999 CA PHE 179-10. 126 4.444 1.168 1.00 0.00 ATOM 1000 HA PHE 179-10.430 5.460 1.365 1.00 0.00 ATOM 1001 CB PHE 179-8.810 4.159 1.888 1.00 0.00 ATOM 1002 1HB PHE 179-8.063 4.811 1.491 1.00 0.00 ATOM 1003 2HB PHE 179-8.511 3.144 1.693 1.00 0.00 ATOM 1004 QB PHE 179-8. 287 3.977 1.592 1.00 0.00 ATOM 1005 QD PHE 179-8.870 4.381 3.544 1.00 0.00 ATOM 1006 QE PHE 179-8.966 4.721 5.978 1.00 0.00 ATOM 1007 QR PHE 179-8.937 4.619 5.248 1.00 0.00 ATOM 1008 CG PHE 179-8.864 4.360 3.378 1.00 0.00 ATOM 1009 CD1 PHE 179-8.411 5.539 3.945 1.00 0.00 ATOM 1010 1HD PHE 179-8.013 6.315 3.307 1.00 0.00 ATOM 1011 CE1 PHE 179-8.463 5.732 5.312 1.00 0.00 ATOM 1012 1HE PHE 179-8.106 6.657 5.741 1.00 0.00 ATOM 1013 CZ PHE 179-8.971 4.742 6.130 1.00 0.00 ATOM 1014 HZ PHE 179-9.013 4.892 7.199 1.00 0.00 ATOM 1015 CE2 PHE 179-9. 426 3.561 5.578 1.00 0.00 ATOM 1016 2HE PHE 179-9.827 2.785 6.215 1.00 0.00 ATOM 1017 CD2 PHE 179-9.371 3.373 4.211 1.00 0.00 ATOM 1018 2HD PHE 179-9.727 2.448 3.781 1.00 0.00 ATOM 1019 C PHE 179-9.914 4.260-0.319 1.00 0.00 ATOM 1020 O PHE 179-10.633 3.500-0. 965 1.00 0.00 ATOM 1021 N ARG+ 180-8.905 4.934-0.845 1.00 0. 00 ATOM 1022 H ARG+ 180-8.363 5.508-0.261 1.00 0.00 ATOM 1023 CA ARG+ 180-8.559 4.834-2.257 1.00 0.00 ATOM 1024 HA ARG+ 180-9.002 3.929-2.650 1.00 0.00 ATOM 1025 CB ARG+ 180-9.094 6.035-3.044 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.767 5.942-4.070 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.681 6.938-2.631 1.00 0.00 ATOM 1028 QB ARG+ 180-8.724 6.440-3.351 1.00 0.00 ATOM 1029 CG ARG+ 180-10.607 6.148-3.038 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.958 6. 086-2.018 1.00 0.00 ATOM 1031 2HG ARG+ 180-11.019 5.331-3.613 1.00 0.00 ATOM 1032 QG ARG+ 180-10.988 5.708-2.816 1.00 0.00 ATOM 1033 CD ARG+ 180-11.073 7.458-3.645 1.00 0.00 ATOM 1034 1HD ARG+ 180-11.957 7.267-4.237 1.00 0.00 ATOM 1035 2HD ARG+ 180-10.291 7.845-4.282 1.00 0.00 ATOM 1036 QD ARG+ 180-11.124 7.556-4.260 1.00 0.00 ATOM 1037 NE ARG+ 180-11.391 8.455-2.625 1.00 0.00 ATOM 1038 HE ARG+ 180-10.959 8.358-1.744 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.234 9.467-2.823 1.00 0.00 ATOM 1040 NH1 ARG+ 180-12.807 9.626-4.012 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.606 8.985-4.755 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-13.442 10.383-4.169 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.024 9.684-4.462 1.00 0.00 ATOM 1044 NH2 ARG+ 180-12.499 10.316-1.837 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.066 10.194-0.935 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.130 11.079-1.983 1.00 0.00 ATOM 1047 QH2 ARG+ 180-12.598 10.636-1.459 1.00 0.00 ATOM 1048 C ARG+ 180-7.048 4.757-2.427 1.00 0.00 ATOM 1049 O ARG+ 180-6.551 4.359-3.468 1.00 0.00 ATOM 1050 N GLY 181-6.313 5.148-1.404 1.00 0.00 ATOM 1051 H GLY 181-6.748 5.459-0.578 1.00 0.00 ATOM 1052 CA GLY 181-4.871 5.126-1.502 1.00 0.00 ATOM 1053 1HA GLY 181-4.485 6.073-1.157 1.00 0. 00 ATOM 1054 2HA GLY 181-4.600 5.000-2.540 1.00 0.00 ATOM 1055 QA GLY 181-4.542 5.536-1.849 1.00 0.00 ATOM 1056 C GLY 181-4.230 4.021-0.701 1.00 0.00 ATOM 1057 O GLY 181-4.811 3.522 0.261 1.00 0.00 ATOM 1058 N VAL 182-3.021 3.650-1.105 1.00 0. 00 ATOM 1059 H VAL 182-2.625 4.103-1.872 1.00 0.00 ATOM 1060 CA VAL 182-2.258 2.602-0.444 1.00 0.00

ATOM 1061 HA VAL 182-2.582 2.544 0.587 1.00 0.00 ATOM 1062 CB VAL 182-2.462 1.215-1.108 1.00 0.00 ATOM 1063 HB VAL 182-1.668 1.073-1. 828 1.00 0.00 ATOM 1064 QG1 VAL 182-2.330-0. 154 0.169 1.00 0.00 ATOM 1065 QG2 VAL 182-4.105 1.096-2.019 1.00 0.00 ATOM 1066 CG1 VAL 182-2.355 0.109-0. 075 1.00 0.00 ATOM 1067 1HG1 VAL 182-3. 042-0.685-0.327 1.00 0.00 ATOM 1068 2HG1 VAL 182-2.600 0.502 0.901 1.00 0.00 ATOM 1069 3HG1 VAL 182-1.347-0. 279-0.065 1.00 0.00 ATOM 1070 CG2 VAL 182-3.791 1.119-1.845 1.00 0.00 ATOM 1071 1HG2 VAL 182-3.698 1.580-2. 817 1.00 0.00 ATOM 1072 2HG2 VAL 182-4.555 1. 628-1. 276 1.00 0.00 ATOM 1073 3HG2 VAL 182-4.063 0.080-1. 963 1.00 0.00 ATOM 1074 QQG VAL 182-3. 217 0.471-0.925 1.00 0.00 ATOM 1075 C VAL 182-0.762 2.932-0.479 1.00 0.00 ATOM 1076 O VAL 182-0. 178 3.071-1. 552 1.00 0.00 ATOM 1077 N GLU 183-0.158 3.042 0.696 1.00 0.00 ATOM 1078 H GLU 183-0.688 2.911 1.512 1.00 0.00 ATOM 1079 CA GLU 183 1.267 3.334 0.830 1.00 0.00 ATOM 1080 HA GLU 183 1.711 3.345-0. 159 1.00 0.00 ATOM 1081 CB GLU 183 1.476 4.697 1.501 1.00 0.00 ATOM 1082 1HB GLU 183 1.727 5.423 0.740 1.00 0.00 ATOM 1083 2HB GLU 183 2.302 4.619 2.192 1.00 0.00 ATOM 1084 QB GLU 183 2.015 5.021 1.466 1.00 0.00 ATOM 1085 CG GLU 183 0.267 5.216 2.269 1.00 0.00 ATOM 1086 1HG GLU 183 0.049 4.532 3.075 1.00 0.00 ATOM 1087 2HG GLU 183-0.577 5.265 1.599 1.00 0.00 ATOM 1088 QG GLU 183-0.264 4.898 2.337 1.00 0.00 ATOM 1089 CD GLU 183 0.501 6.594 2.853 1.00 0.00 ATOM 1090 OE1 GLU 183 1.525 6.781 3.536 1.00 0.00 ATOM 1091 OE2 GLU 183-0.331 7.493 2.610 1.00 0.00 ATOM 1092 C GLU 183 1.922 2.237 1.666 1.00 0.00 ATOM 1093 O GLU 183 1.913 2.290 2.889 1.00 0.00 ATOM 1094 N PHE 184 2.449 1.222 1.008 1.00 0.00 ATOM 1095 H PHE 184 2.405 1.208 0.034 1.00 0.00 ATOM 1096 CA PHE 184 3.051 0.096 1.709 1.00 0.00 ATOM 1097 HA PHE 184 2.905 0.256 2.765 1.00 0.00 ATOM 1098 CB PHE 184 2.360-1.213 1.308 1.00 0.00 ATOM 1099 1HB PHE 184 1.465-1.340 1.900 1.00 0.00 ATOM 1100 2HB PHE 184 3.030-2.036 1.516 1.00 0.00 ATOM 1101 QB PHE 184 2.248-1.688 1.708 1.00 0.00 ATOM 1102 QD PHE 184 1.928-1.308-0.325 1.00 0.00 ATOM 1103 QE PHE 184 1.284-1.491-2.690 1.00 0.00 ATOM 1104 QR PHE 184 1.476-1.438-1.981 1.00 0.00 ATOM 1105 CG PHE 184 1.974-1.298-0.155 1.00 0.00 ATOM 1106 CD1 PHE 184 2.597-2.207-0.994 1.00 0.00 ATOM 1107 1HD PHE 184 3.377-2.841-0.600 1.00 0.00 ATOM 1108 CE1 PHE 184 2.234-2.313-2.323 1.00 0.00 ATOM 1109 1HE PHE 184 2.732-3.027-2.963 1.00 0.00 ATOM 1110 CZ PHE 184 1.242-1.505-2.835 1.00 0.00 ATOM 1111 HZ PHE 184 0.953-1.592-3.872 1.00 0.00 ATOM 1112 CE2 PHE 184 0.613-0.591-2.018 1.00 0.00 ATOM 1113 2HE PHE 184-0.164 0.046-2.416 1.00 0.00 ATOM 1114 CD2 PHE 184 0.974-0.492-0.687 1.00 0.00 ATOM 1115 2HD PHE 184 0.479 0.226-0.050 1.00 0.00 ATOM 1116 C PHE 184 4.539-0.031 1.438 1.00 0.00 ATOM 1117 O PHE 184 5.003 0.231 0.337 1.00 0.00 ATOM 1118 N VAL 185 5.277-0.459 2.449 1.00 0.00 ATOM 1119 H VAL 185 4.844-0.664 3.305 1.00 0.00 ATOM 1120 CA VAL 185 6.710-0.648 2.322 1.00 0.00 ATOM 1121 HA VAL 185 7.005-0.332 1.330 1.00 0.00 ATOM 1122 CB VAL 185 7.489 0.192 3.363 1.00 0.00 ATOM 1123 HB VAL 185 7.672-0.426 4.235 1.00 0. 00 ATOM 1124 QG1 VAL 185 9.142 0.743 2.673 1.00 0.00 ATOM 1125 QG2 VAL 185 6.494 1.692 3.909 1.00 0.00 ATOM 1126 CG1 VAL 185 8.826 0.637 2.805 1.00 0.00 ATOM 1127 1HG1 VAL 185 8.786 1.692 2.578 1.00 0.00 ATOM 1128 2HG1 VAL 185 9.043 0.083 1.904 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.598 0.456 3.538 1.00 0.00 ATOM 1130 CG2 VAL 185 6.685 1.405 3.803 1.00 0.00 ATOM 1131 1HG2 VAL 185 5.632 1.163 3.790 1.00 0.00 ATOM 1132 2HG2 VAL 185 6.874 2.228 3.131 1.00 0.00

ATOM 1133 3HG2 VAL 185 6.976 1.685 4.806 1.00 0.00 ATOM 1134 QQG VAL 185 7.818 1.218 3.291 1.00 0.00 ATOM 1135 C VAL 185 7.044-2. 131 2.485 1.00 0.00 ATOM 1136 0 VAL 185 6.907-2. 693 3.569 1.00 0.00 ATOM 1137 N CYS 186 7.455-2.774 1.398 1.00 0.00 ATOM 1138 H CYS 186 7.527-2.284 0.547 1.00 0.00 ATOM 1139 CA CYS 186 7.781-4.196 1.435 1.00 0.00 ATOM 1140 HA CYS 186 7.536-4.561 2.423 1.00 0.00 ATOM 1141 CB CYS 186 6.948-4.969 0.405 1.00 0.00 ATOM 1142 1HB CYS 186 5.961-5.138 0.810 1.00 0.00 ATOM 1143 2HB CYS 186 7.420-5.919 0.220 1.00 0.00 ATOM 1144 QB CYS 186 6. 691-5. 529 0. 515 1.00 0.00 ATOM 1145 SG CYS 186 6.754-4.149-1.205 1.00 0.00 ATOM 1146 C CYS 186 9.268-4.429 1.188 1.00 0.00 ATOM 1147 O CYS 186 9.823-3.936 0.216 1.00 0.00 ATOM 1148 N CYS 187 9.915-5.189 2.063 1.00 0.00 ATOM 1149 H CYS 187 9.426-5.574 2.823 1.00 0.00 ATOM 1150 CA CYS 187 11.346-5.467 1.905 1.00 0.00 ATOM 1151 HA CYS 187 11.775-4.656 1.339 1.00 0.00 ATOM 1152 CB CYS 187 12.047-5. 548 3.265 1.00 0.00 ATOM 1153 1HB CYS 187 12.857-6.261 3.201 1.00 0.00 ATOM 1154 2HB CYS 187 11.340-5.881 4.009 1.00 0.00 ATOM 1155 QB CYS 187 12.099-6.071 3.605 1.00 0.00 ATOM 1156 SG CYS 187 12.745-3.965 3.833 1.00 0.00 ATOM 1157 C CYS 187 11.570-6.759 1.141 1.00 0.00 ATOM 1158 O CYS 187 10.706-7.630 1.134 1.00 0.00 ATOM 1159 N PRO 188 12.731-6.889 0.472 1.00 0.00 ATOM 1160 CD PRO 188 13.807-5.879 0.419 1.00 0.00 ATOM 1161 CA PRO 188 13.058-8.083-0.313 1.00 0.00 ATOM 1162 HA PRO 188 12.315-8.267-1.076 1.00 0.00 ATOM 1163 CB PRO 188 14.395-7.737-0.978 1.00 0.00 ATOM 1164 1HB PRO 188 14.222-7.423-1.996 1.00 0.00 ATOM 1165 2HB PRO 188 15.034-8.609-0.970 1.00 0.00 ATOM 1166 QB PRO 188 14.628-8.016-1.483 1.00 0.00 ATOM 1167 CG PRO 188 14.972-6.634-0.157 1.00 0.00 ATOM 1168 1HG PRO 188 15.567-5.984-0.782 1.00 0.00 ATOM 1169 2HG PRO 188 15.578-7.048 0.636 1.00 0.00 ATOM 1170 QG PRO 188 15.573-6. 516-0.073 1.00 0.00 ATOM 1171 1HD PRO 188 13.535-5.054-0.223 1.00 0.00 ATOM 1172 2HD PRO 188 14.046-5.521 1.409 1.00 0.00 ATOM 1173 QD PRO 188 13.791-5.288 0.593 1.00 0.00 ATOM 1174 C PRO 188 13.202-9.335 0.549 1.00 0.00 ATOM 1175 O PRO 188 13.920-9.331 1.553 1.00 0.00 ATOM 1176 N LEU 189 12.516-10.393 0.139 1.00 0.00 ATOM 1177 H LEU 189 11.969-10.317-0.672 1.00 0.00 ATOM 1178 CA LEU 189 12.550-11.666 0.837 1.00 0.00 ATOM 1179 HA LEU 189 13.376-11.649 1.531 1.00 0.00 ATOM 1180 CB LEU 189 11.242-11.889 1.604 1.00 0.00 ATOM 1181 1HB LEU 189 10.550-12.391 0.944 1.00 0.00 ATOM 1182 2HB LEU 189 10.832-10.923 1.856 1.00 0.00 ATOM 1183 QB LEU 189 10.691-11.657 1.400 1.00 0.00 ATOM 1184 CG LEU 189 11.355-12.713 2.893 1.00 0.00 ATOM 1185 HG LEU 189 10.592-12.387 3.585 1.00 0.00 ATOM 1186 QD1 LEU 189 11.072-14.537 2.536 1.00 0.00 ATOM 1187 QD2 LEU 189 13.030-12.456 3.709 1.00 0.00 ATOM 1188 CD1 LEU 189 11.125-14.188 2.606 1.00 0.00 ATOM 1189 1HD1 LEU 189 11.691-14.473 1.730 1.00 0.00 ATOM 1190 2HD1 LEU 189 10.075-14.361 2.429 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.451-14.775 3.451 1.00 0.00 ATOM 1192 CD2 LEU 189 12.709-12.505 3.554 1.00 0.00 ATOM 1193 1HD2 LEU 189 13.478-12.961 2.947 1. 00 0. 00 ATOM 1194 2HD2 LEU 189 12.706-12.959 4.533 1.00 0.00 ATOM 1195 3HD2 LEU 189 12.905-11.447 3.647 1.00 0.00 ATOM 1196 QQD LEU 189 12.051-13.496 3.122 1.00 0.00 ATOM 1197 C LEU 189 12.763-12.795-0.169 1.00 0.00 ATOM 1198 OT1 LEU 189 12.218-12.692-1.290 1. 00 0. 00 ATOM 1199 OT2 LEU 189 13.476-13.764 0.164 1. oo o. oo TER ENDMDL MODEL 21 ATOM I N SER 124 15.485 12.648-5.476 1. 00 0. 00 ATOM 2 CA SER 124 14.135 12.049-5.382 1. 00 0. 00

ATOM 3 HA SER 124 13.541 12.386-6.218 1.00 0.00 ATOM 4 CB SER 124 14.294 10.531-5.444 1.00 0.00 ATOM 5 1HB SER 124 13.595 10.123-6.160 1.00 0.00 ATOM 6 2HB SER 124 14.100 10.109-4.467 1.00 0.00 ATOM 7 QB SER 124 13.848 10.116-5.314 1.00 0.00 ATOM 8 OG SER 124 15.614 10.187-5.841 1.00 0.00 ATOM 9 HG SER 124 15.752 9.238-5.720 1.00 0.00 ATOM 10 C SER 124 13.463 12.463-4.083 1.00 0.00 ATOM 11 O SER 124 14.084 13. 118-3.248 1.00 0.00 ATOM 12 1HT SER 124 16.190 11.901-5.648 1.00 0.00 ATOM 13 2HT SER 124 15.718 13.134-4.586 1.00 0.00 ATOM 14 3HT SER 124 15.521 13.334-6.254 1.00 0.00 ATOM 15 N ASP 125 12.204 12.078-3.919 1.00 0.00 ATOM 16 H ASP 125 11.767 11.555-4.621 1.00 0.00 ATOM 17 CA ASP 125 11.453 12.409-2.716 1.00 0.00 ATOM 18 HA ASP 125 11.849 13.332-2.317 1.00 0.00 ATOM 19 CB ASP 125 9.975 12.603-3.052 1.00 0.00 ATOM 20 1HB ASP 125 9.473 11.648-3.016 1.00 0.00 ATOM 21 2HB ASP 125 9.885 13.018-4.044 1.00 0.00 ATOM 22 QB ASP 125 9.679 12.333-3.530 1.00 0.00 ATOM 23 CG ASP 125 9.290 13.538-2.083 1.00 0.00 ATOM 24 OD1 ASP 125 9.371 14.762-2.288 1.00 0.00 ATOM 25 OD2 ASP 125 8.688 13.042-1.111 1.00 0.00 ATOM 26 C ASP 125 11.607 11.312-1.671 1.00 0.00 ATOM 27 O ASP 125 12.186 10.259-1.949 1.00 0.00 ATOM 28 N ALA 126 11.072 11.555-0.482 1.00 0.00 ATOM 29 H ALA 126 10.606 12.409-0.336 1.00 0.00 ATOM 30 CA ALA 126 11.130 10.584 0.603 1.00 0.00 ATOM 31 HA ALA 126 11.877 9.844 0.351 1.00 0.00 ATOM 32 QB ALA 126 11.638 11.417 2.212 1.00 0.00 ATOM 33 CB ALA 126 11.542 11.258 1.904 1.00 0.00 ATOM 34 1HB ALA 126 12.598 11.109 2.069 1.00 0.00 ATOM 35 2HB ALA 126 10.985 10.826 2.723 1.00 0.00 ATOM 36 3HB ALA 126 11.331 12.316 1.844 1.00 0.00 ATOM 37 C ALA 126 9.781 9.894 0.765 1.00 0.00 ATOM 38 O ALA 126 9.498 9.283 1.796 1.00 0.00 ATOM 39 N LEU 127 8.953 10.006-0.265 1.00 0.00 ATOM 40 H LEU 127 9.242 10.514-1.050 1.00 0.00 ATOM 41 CA LEU 127 7.625 9.410-0.264 1.00 0.00 ATOM 42 HA LEU 127 7.302 9.314 0.760 1.00 0.00 ATOM 43 CB LEU 127 6.651 10.319-1.018 1.00 0.00 ATOM 44 1HB LEU 127 6.716 10.078-2.068 1.00 0.00 ATOM 45 2HB LEU 127 6.970 11.344-0.882 1.00 0.00 ATOM 46 QB LEU 127 6.843 10.711-1.475 1.00 0.00 ATOM 47 CG LEU 127 5.185 10.211-0.594 1.00 0.00 ATOM 48 HG LEU 127 4.926 9.168-0.477 1.00 0.00 ATOM 49 QD1 LEU 127 4.901 11.072 1.052 1.00 0.00 ATOM 50 QD2 LEU 127 4.068 10.943-1.917 1. 00 0.00 ATOM 51 CD1 LEU 127 4.956 10.907 0.737 1.00 0.00 ATOM 52 1HD1 LEU 127 5.671 11.708 0.852 1.00 0.00 ATOM 53 2HD1 LEU 127 5.077 10.196 1.541 1.00 0.00 ATOM 54 3HD1 LEU 127 3.955 11.311 0.763 1.00 0.00 ATOM 55 CD2 LEU 127 4.282 10.803-1.664 1.00 0.00 ATOM 56 1HD2 LEU 127 4.546 11.838-1.825 1.00 0.00 ATOM 57 2HD2 LEU 127 3.253 10.739-1.341 1.00 0.00 ATOM 58 3HD2 LEU 127 4.405 10.253-2.585 1.00 0.00 ATOM 59 QQD LEU 127 4.485 11. 007-0. 433 1.00 0.00 ATOM 60 C LEU 127 7.652 8.029-0.914 1.00 0.00 ATOM 61 O LEU 127 6.610 7.456-1.236 1.00 0.00 ATOM 62 N LEU 128 8.850 7.499-1.103 1.00 0.00 ATOM 63 H LEU 128 9.641 8.000-0.824 1.00 0.00 ATOM 64 CA LEU 128 9.017 6.191-1.709 1.00 0.00 ATOM 65 HA LEU 128 8.065 5.690-1.684 1.00 0.00 ATOM 66 CB LEU 128 9.468 6.340-3.167 1.00 0.00 ATOM 67 1HB LEU 128 10.548 6.325-3.189 1.00 0.00 ATOM 68 2HB LEU 128 9.131 7.301-3.529 1.00 0.00 ATOM 69 QB LEU 128 9.840 6.813-3.359 1.00 0.00 ATOM 70 CG LEU 128 8.953 5.257-4.122 1.00 0.00 ATOM 71 HG LEU 128 8.632 4.399-3.549 1.00 0.00 ATOM 72 QD1 LEU 128 7.471 5.889-5.089 1.00 0.00 ATOM 73 QD2 LEU 128 10.314 4.708-5.298 1.00 0.00 ATOM 74 CD1 LEU 128 7.754 5.768-4.903 1.00 0.00

ATOM 75 1HD1 LEU 128 7.120 6.349-4.250 1.00 0.00 ATOM 76 2HD1 LEU 128 7.197 4.931-5.295 1.00 0.00 ATOM 77 3HD1 LEU 128 8.094 6.388-5.720 1.00 0.00 ATOM 78 CD2 LEU 128 10. 053 4.813-5.072 1.00 0.00 ATOM 79 1HD2 LEU 128 9.684 4.842-6.087 1.00 0.00 ATOM 80 2HD2 LEU 128 10.355 3.806-4.827 1.00 0.00 ATOM 81 3HD2 LEU 128 10.901 5.476-4.978 1.00 0.00 ATOM 82 QQD LEU 128 8.892 5.299-5.193 1.00 0.00 ATOM 83 C LEU 128 10. 021 5.374-0.903 1.00 0.00 ATOM 84 O LEU 128 10.110 5.534 0.312 1.00 0.00 ATOM 85 N VAL 129 10.758 4.501-1.584 1.00 0.00 ATOM 86 H VAL 129 10.618 4.431-2.549 1.00 0.00 ATOM 87 CA VAL 129 11.761 3.636-0.949 1.00 0.00 ATOM 88 HA VAL 129 11.239 2.891-0.369 1.00 0.00 ATOM 89 CB VAL 129 12.612 2.909-2.017 1.00 0.00 ATOM 90 HB VAL 129 13.248 3.641-2.494 1.00 0.00 ATOM 91 QG1 VAL 129 13.715 1.602-1.234 1.00 0.00 ATOM 92 QG2 VAL 129 11. 513 2.140-3.333 1.00 0.00 ATOM 93 CG1 VAL 129 13.503 1.852-1.384 1.00 0.00 ATOM 94 1HG1 VAL 129 12.947 1.315-0.629 1.00 0.00 ATOM 95 2HG1 VAL 129 14.359 2.329-0.928 1.00 0.00 ATOM 96 3HG1 VAL 129 13.839 1.162-2.143 1.00 0.00 ATOM 97 CG2 VAL 129 11.722 2.287-3.081 1.00 0.00 ATOM 98 1HG2 VAL 129 10.689 2.516-2.867 1.00 0.00 ATOM 99 2HG2 VAL 129 11.861 1.216-3.083 1.00 0.00 ATOM 100 3HG2 VAL 129 11.987 2.687-4.049 1.00 0.00 ATOM 101 QQG VAL 129 12.614 1.871-2.283 1.00 0.00 ATOM 102 C VAL 129 12.697 4.420-0.021 1.00 0.00 ATOM 103 O VAL 129 13.505 5.225-0.481 1.00 0.00 ATOM 104 N PRO 130 12.584 4.194 1.304 1.00 0.00 ATOM 105 CD PRO 130 11.638 3.277 1.937 1.00 0.00 ATOM 106 CA PRO 130 13.401 4.869 2.305 1.00 0.00 ATOM 107 HA PRO 130 13.577 5.892 2.043 1. 00 0.00 ATOM 108 CB PRO 130 12. 537 4.808 3.579 1.00 0.00 ATOM 109 1HB PRO 130 12.239 5.810 3.853 1.00 0.00 ATOM 110 2HB PRO 130 13. 114 4.374 4.381 1.00 0.00 ATOM 111 QB PRO 130 12.677 5.092 4.117 1.00 0.00 ATOM 112 CG PRO 130 11.343 3.960 3.245 1.00 0.00 ATOM 113 1HG PRO 130 10.468 4.587 3.148 1.00 0.00 ATOM 114 2HG PRO 130 11. 189 3.225 4.021 1.00 0. 00 ATOM 115 QG PRO 130 10.829 3.906 3. 584 1.00 0.00 ATOM 116 1HD PRO 130 10.739 3.183 1.346 1.00 0.00 ATOM 117 2HD PRO 130 12.089 2.309 2.103 1.00 0.00 ATOM 118 QD PRO 130 11.414 2.746 1.724 1.00 0.00 ATOM 119 C PRO 130 14.744 4.181 2.535 1.00 0.00 ATOM 120 O PRO 130 15.748 4.520 1.913 1.00 0.00 ATOM 121 N ASP 131 14.743 3.230 3.454 1.00 0.00 ATOM 122 H ASP 131 13.907 3.036 3.912 1.00 0.00 ATOM 123 CA ASP 131 15.948 2.484 3.812 1.00 0.00 ATOM 124 HA ASP 131 16.790 3.155 3.724 1.00 0.00 ATOM 125 CB ASP 131 15.838 2.011 5.269 1.00 0.00 ATOM 126 1HB ASP 131 15.005 1.330 5.358 1.00 0.00 ATOM 127 2HB ASP 131 15.663 2.867 5.903 1.00 0.00 ATOM 128 QB ASP 131 15.334 2.098 5.630 1.00 0. 00 ATOM 129 CG ASP 131 17.083 1.309 5.760 1.00 0.00 ATOM 130 OD1 ASP 131 16.948 0.299 6.474 1.00 0.00 ATOM 131 OD2 ASP 131 18.196 1.750 5.422 1.00 0. 00 ATOM 132 C ASP 131 16.168 1.294 2.869 1.00 0.00 ATOM 133 O ASP 131 16. 641 1.459 1.748 1.00 0.00 ATOM 134 N LYS+ 132 15.820 0.094 3.326 1.00 0.00 ATOM 135 H LYS+ 132 15.450 0.018 4.229 1.00 0.00 ATOM 136 CA LYS+ 132 15.985-1.110 2.513 1.00 0.00 ATOM 137 HA LYS+ 132 16.541-0.837 1.627 1.00 0.00 ATOM 138 CB LYS+ 132 16.761-2.184 3.281 1.00 0.00 ATOM 139 1HB LYS+ 132 17.023-2.978 2.596 1. 00 0. 00 ATOM 140 2HB LYS+ 132 16.124-2.586 4.055 1.00 0.00 ATOM 141 QB LYS+ 132 16.574-2.782 3.325 1. 00 0. 00 ATOM 142 CG LYS+ 132 18.038-1.676 3.931 1. 00 0.00 ATOM 143 1HG LYS+ 132 17.851-0.694 4.345 1. 00 0.00 ATOM 144 2HG LYS+ 132 18.813-1.613 3.182 1.00 0.00 ATOM 145 QG LYS+ 132 18.332-1.154 3.763 1.00 0.00 ATOM 146 CD LYS+ 132 18.499-2.603 5.046 1. 00 0. 00

ATOM 147 1HD LYS+ 132 19.241-3.283 4.653 1.00 0.00 ATOM 148 2HD LYS+ 132 17.648-3.165 5.405 1.00 0.00 ATOM 149 QD LYS+ 132 18.445-3.224 5.029 1.00 0.00 ATOM 150 CE LYS+ 132 19.103-1.830 6.212 1.00 0.00 ATOM 151 1HE LYS+ 132 19.923-2.402 6.621 1.00 0.00 ATOM 152 2HE LYS+ 132 18.343-1.700 6.970 1.00 0.00 ATOM 153 QE LYS+ 132 19.133-2.051 6. 795 1.00 0.00 ATOM 154 NZ LYS+ 132 19.603-0.488 5.799 1.00 0.00 ATOM 155 1HZ LYS+ 132 19.916-0.506 4.812 1.00 0.00 ATOM 156 2HZ LYS+ 132 20. 394-0. 194 6.401 1.00 0.00 ATOM 157 3HZ LYS+ 132 18. 832 0.226 5.890 1.00 0.00 ATOM 158 QZ LYS+ 132 19.714-0.158 5.701 1.00 0.00 ATOM 159 C LYS+ 132 14.631-1.663 2.094 1.00 0.00 ATOM 160 O LYS+ 132 14.541-2.606 1.308 1.00 0.00 ATOM 161 N CYS 133 13.576-1.069 2.623 1.00 0. 00 ATOM 162 H CYS 133 13.710-0.322 3.239 1.00 0.00 ATOM 163 CA CYS 133 12.224-1.496 2.304 1.00 0.00 ATOM 164 HA CYS 133 12.263-2.530 1.998 1.00 0.00 ATOM 165 CB CYS 133 11.315-1.363 3.527 1.00 0.00 ATOM 166 1HB CYS 133 10.316-1.127 3.192 1.00 0.00 ATOM 167 2HB CYS 133 11.674-0.556 4.142 1.00 0.00 ATOM 168 QB CYS 133 10.995-0.842 3.667 1.00 0.00 ATOM 169 SG CYS 133 11.203-2.846 4.583 1.00 0.00 ATOM 170 C CYS 133 11.673-0.658 1.161 1.00 0.00 ATOM 171 O CYS 133 12.072 0.485 0.976 1.00 0.00 ATOM 172 N LYS+ 134 10.753-1.225 0.403 1.00 0.00 ATOM 173 H LYS+ 134 10.463-2.140 0. 607 1.00 0.00 ATOM 174 CA LYS+ 134 10.147-0.525-0.719 1.00 0.00 ATOM 175 HA LYS+ 134 10.834 0.240-1.049 1.00 0.00 ATOM 176 CB LYS+ 134 9.879-1.500-1.870 1.00 0.00 ATOM 177 1HB LYS+ 134 8.890-1.918-1.744 1.00 0.00 ATOM 178 2HB LYS+ 134 10.604-2.298-1.824 1.00 0.00 ATOM 179 QB LYS+ 134 9.747-2.108-1.784 1.00 0.00 ATOM 180 CG LYS+ 134 9.954-0.863-3.251 1.00 0.00 ATOM 181 1HG LYS+ 134 10.957-0.976-3.637 1.00 0.00 ATOM 182 2HG LYS+ 134 9.718 0.188-3.164 1.00 0. 00 ATOM 183 QG LYS+ 134 10.338-0.394-3.401 1.00 0.00 ATOM 184 CD LYS+ 134 8.972-1.508-4.220 1.00 0.00 ATOM 185 1HD LYS+ 134 8.341-0.737-4.641 1.00 0.00 ATOM 186 2HD LYS+ 134 8.361-2.217-3.681 1.00 0.00 ATOM 187 QD LYS+ 134 8.351-1.477-4.161 1.00 0.00 ATOM 188 CE LYS+ 134 9.687-2.232-5.353 1.00 0.00 ATOM 189 1HE LYS+ 134 10.130-1.497-6.010 1.00 0.00 ATOM 190 2HE LYS+ 134 8.961-2.815-5.904 1.00 0.00 ATOM 191 QE LYS+ 134 9.546-2.156-5.957 1.00 0.00 ATOM 192 NZ LYS+ 134 10.756-3.142-4.848 1.00 0.00 ATOM 193 1HZ LYS+ 134 11.504-3.249-5.564 1.00 0.00 ATOM 194 2HZ LYS+ 134 10.359-4.080-4.638 1. 00 0.00 ATOM 195 3HZ LYS+ 134 11.176-2.754-3.980 1.00 0.00 ATOM 196 QZ LYS+ 134 11.013-3.361-4.728 1.00 0.00 ATOM 197 C LYS+ 134 8.849 0.127-0.278 1.00 0.00 ATOM 198 O LYS+ 134 7.872-0.563-0.006 1.00 0.00 ATOM 199 N PHE 135 8.845 1.447-0.205 1.00 0.00 ATOM 200 H PHE 135 9.657 1.943-0.435 1.00 0.00 ATOM 201 CA PHE 135 7.658 2.180 0.210 1.00 0.00 ATOM 202 HA PHE 135 7.060 1.525 0.826 1.00 0.00 ATOM 203 CB PHE 135 8.057 3.414 1.025 1.00 0.00 ATOM 204 1HB PHE 135 8.623 4.083 0.391 1.00 0.00 ATOM 205 2HB PHE 135 8.678 3.104 1.850 1.00 0.00 ATOM 206 QB PHE 135 8.651 3.593 1.120 1.00 0.00 ATOM 207 QD PHE 135 6.776 4.279 1.658 1.00 0.00 ATOM 208 QE PHE 135 4.902 5.562 2.601 1.00 0.00 ATOM 209 QR PHE 135 5.464 5.178 2.319 1.00 0.00 ATOM 210 CG PHE 135 6.902 4.192 1.593 1.00 0.00 ATOM 211 CD1 PHE 135 6.943 5.575 1.634 1.00 0.00 ATOM 212 1HD PHE 135 7.810 6.092 1.245 1.00 0.00 ATOM 213 CE1 PHE 135 5.893 6.299 2.163 1.00 0.00 ATOM 214 1HE PHE 135 5.937 7.378 2.189 1. 00 0. 00 ATOM 215 CZ PHE 135 4.786 5.642 2.659 1.00 0.00 ATOM 216 HZ PHE 135 3.960 6.205 3.075 1.00 0.00 ATOM 217 CE2 PHE 135 4.733 4.263 2.625 1.00 0.00 ATOM 218 2HE PHE 135 3.867 3.746 3.014 1.00 0.00

ATOM 219 CD2 PHE 135 5.786 3.545 2.095 1.00 0.00 ATOM 220 2HD PHE 135 5.742 2.467 2.071 1.00 0.00 ATOM 221 C PHE 135 6.849 2.584-1.009 1.00 0.00 ATOM 222 O PHE 135 7.287 3.399-1.821 1.00 0.00 ATOM 223 N LEU 136 5.675 1.991-1.136 1.00 0.00 ATOM 224 H LEU 136 5.390 1.339-0.457 1.00 0.00 ATOM 225 CA LEU 136 4.798 2.264-2.254 1.00 0.00 ATOM 226 HA LEU 136 5.357 2.825-2.986 1.00 0.00 ATOM 227 CB LEU 136 4.304 0.960-2.891 1.00 0.00 ATOM 228 1HB LEU 136 3.597 1.213-3.667 1.00 0.00 ATOM 229 2HB LEU 136 3.787 0.390-2.133 1.00 0.00 ATOM 230 QB LEU 136 3.692 0. 801-2.900 1.00 0.00 ATOM 231 CG LEU 136 5.389 0.074-3.504 1.00 0.00 ATOM 232 HG LEU 136 6.246 0.681-3.749 1.00 0.00 ATOM 233 QD1 LEU 136 5.934-1.240-2.277 1.00 0.00 ATOM 234 QD2 LEU 136 4.767-0.729-5.085 1.00 0.00 ATOM 235 CD1 LEU 136 5.830-0.988-2.513 1.00 0.00 ATOM 236 1HD1 LEU 136 6.501-0.549-1.789 1.00 0.00 ATOM 237 2HD1 LEU 136 6.336-1.784-3.038 1.00 0.00 ATOM 238 3HD1 LEU 136 4.964-1.387-2.004 1.00 0.00 ATOM 239 CD2 LEU 136 4.886-0.575-4.783 1.00 0.00 ATOM 240 1HD2 LEU 136 5.432-0.180-5.626 1.00 0.00 ATOM 241 2HD2 LEU 136 3.834-0.363-4.903 1.00 0.00 ATOM 242 3HD2 LEU 136 5.033-1.643-4.726 1.00 0.00 ATOM 243 QQD LEU 136 5.350-0.984-3.681 1.00 0.00 ATOM 244 C LEU 136 3.607 3.087-1.805 1.00 0.00 ATOM 245 O LEU 136 2.536 2.546-1.540 1.00 0.00 ATOM 246 N HIS+ 137 3.786 4.395-1.743 1.00 0.00 ATOM 247 H HIS+ 137 4.656 4.775-1.983 1.00 0.00 ATOM 248 CA HIS+ 137 2.702 5.277-1.359 1.00 0.00 ATOM 249 HA HIS+ 137 1.997 4.703-0.768 1.00 0.00 ATOM 250 CB HIS+ 137 3.218 6.477-0.536 1.00 0.00 ATOM 251 1HB HIS+ 137 4.085 6.892-1.029 1.00 0.00 ATOM 252 2HB HIS+ 137 3.503 6.133 0.447 1.00 0.00 ATOM 253 QB HIS+ 137 3.794 6.512-0.291 1.00 0.00 ATOM 254 CG HIS+ 137 2.212 7.590-0.359 1.00 0.00 ATOM 255 ND1 HIS+ 137 1.615 7.897 0.847 1.00 0.00 ATOM 256 CD2 HIS+ 137 1.694 8.465-1.256 1.00 0.00 ATOM 257 1HD HIS+ 137 1.779 7.439 1.713 1.00 0.00 ATOM 258 CE1 HIS+ 137 0.776 8.906 0.677 1.00 0.00 ATOM 259 NE2 HIS+ 137 0.803 9.270-0.594 1.00 0.00 ATOM 260 2HD HIS+ 137 1.933 8.514-2.311 1.00 0.00 ATOM 261 1HE HIS+ 137 0.168 9.356 1.449 1.00 0.00 ATOM 262 2HE HIS+ 137 0.104 9.814-1.038 1.00 0.00 ATOM 263 C HIS+ 137 2.021 5.759-2.630 1.00 0.00 ATOM 264 0 HIS+ 137 2.631 6.468-3.434 1.00 0.00 ATOM 265 N GLN 138 0.774 5.364-2.823 1.00 0.00 ATOM 266 H GLN 138 0.340 4.788-2.155 1.00 0.00 ATOM 267 CA GLN 138 0.035 5.764-4.008 1.00 0.00 ATOM 268 HA GLN 138 0.446 6.703-4.350 1.00 0.00 ATOM 269 CB GLN 138 0.185 4.723-5.120 1.00 0.00 ATOM 270 1HB GLN 138-0.648 4.818-5. 800 1 : 00 0.00 ATOM 271 2HB GLN 138 0.165 3.742-4.678 1.00 0.00 ATOM 272 QB GLN 138-0.241 4.280-5.239 1.00 0.00 ATOM 273 CG GLN 138 1.472 4.863-5.920 1.00 0.00 ATOM 274 1HG GLN 138 2.002 5.739-5.571 1.00 0.00 ATOM 275 2HG GLN 138 1.223 4.986-6.963 1.00 0.00 ATOM 276 QG GLN 138 1.613 5.362-6.267 1.00 0.00 ATOM 277 CD GLN 138 2.382 3.659-5.779 1.00 0.00 ATOM 278 OE1 GLN 138 2.042 2.560-6.210 1.00 0.00 ATOM 279 NE2 GLN 138 3.545 3.858-5.173 1.00 0.00 ATOM 280 1HE2 GLN 138 3.755 4.761-4.852 1.00 0.00 ATOM 281 2HE2 GLN 138 4.147 3.092-5.071 1.00 0.00 ATOM 282 QE2 GLN 138 3.951 3.926-4.962 1.00 0.00 ATOM 283 C GLN 138-1.435 5.965-3.685 1.00 0.00 ATOM 284 O GLN 138-2.074 5.116-3.058 1.00 0.00 ATOM 285 N GLU 139-1.960 7.093-4.117 1. 00 0. 00 ATOM 286 H GLU 139-1.392 7.724-4.607 1.00 0.00 ATOM 287 CA GLU 139-3.353 7.430-3.886 1. 00 0. 00 ATOM 288 HA GLU 139-3.694 6.851-3.041 1. 00 0. 00 ATOM 289 CB GLU 139-3.497 8.925-3.558 1. 00 0. 00 ATOM 290 1HB GLU 139-3.496 9.045-2.485 1. 00 0. 00

ATOM 291 2HB GLU 139-4.441 9.274-3.948 1.00 0.00 ATOM 292 QB GLU 139-3.968 9.159-3.217 1.00 0.00 ATOM 293 CG GLU 139-2.392 9.807-4.134 1.00 0.00 ATOM 294 1HG GLU 139-2.774 10.812-4.244 1.00 0.00 ATOM 295 2HG GLU 139-2.113 9.424-5. 104 1.00 0.00 ATOM 296 QG GLU 139-2.443 10.118-4.674 1.00 0.00 ATOM 297 CD GLU 139-1.152 9.855-3.263 1.00 0.00 ATOM 298 OE1 GLU 139-1.223 10.412-2.148 1.00 0.00 ATOM 299 OE2 GLU 139-0.111 9.326-3.693 1.00 0.00 ATOM 300 C GLU 139-4.195 7.062-5.106 1.00 0.00 ATOM 301 O GLU 139-4.199 7.771-6.113 1.00 0.00 ATOM 302 N ARG+ 140-4.905 5.948-5.011 1.00 0.00 ATOM 303 H ARG+ 140-4.865 5.422-4.185 1.00 0.00 ATOM 304 CA ARG+ 140-5.748 5.484-6.104 1.00 0.00 ATOM 305 HA ARG+ 140-5.354 5.888-7.025 1.00 0.00 ATOM 306 CB ARG+ 140-5.732 3.951-6.175 1.00 0. 00 ATOM 307 1HB ARG+ 140-6.352 3.564-5.377 1.00 0.00 ATOM 308 2HB ARG+ 140-4.720 3.605-6.030 1.00 0.00 ATOM 309 QB ARG+ 140-5.536 3.584-5.704 1.00 0.00 ATOM 310 CG ARG+ 140-6.247 3.385-7.490 1.00 0.00 ATOM 311 1HG ARG+ 140-7.102 3.966-7.809 1.00 0.00 ATOM 312 2HG ARG+ 140-6.545 2.359-7.337 1.00 0.00 ATOM 313 QG ARG+ 140-6.823 3.162-7.573 1.00 0.00 ATOM 314 CD ARG+ 140-5.185 3.434-8.578 1.00 0.00 ATOM 315 1HD ARG+ 140-4.213 3.323-8.120 1.00 0.00 ATOM 316 2HD ARG+ 140-5.241 4.395-9.070 1.00 0.00 ATOM 317 QD ARG+ 140-4.727 3.859-8.595 1.00 0.00 ATOM 318 NE ARG+ 140-5. 368 2.378-9.575 1.00 0.00 ATOM 319 HE ARG+ 140-5.122 1.463-9.312 1.00 0. 00 ATOM 320 CZ ARG+ 140-5.822 2.598-10.811 1.00 0.00 ATOM 321 NH1 ARG+ 140-6.229 3.809-11.161 1.00 0.00 ATOM 322 1HH1 ARG+ 140-6.203 4.565-10.494 1.00 0.00 ATOM 323 2HH1 ARG+ 140-6.582 3.981-12.081 1.00 0.00 ATOM 324 QH1 ARG+ 140-6.392 4.273-11.288 1.00 0.00 ATOM 325 NH2 ARG+ 140-5.901 1.597-11.682 1.00 0.00 ATOM 326 1HH2 ARG+ 140-5.620 0.675-11.415 1.00 0.00 ATOM 327 2HH2 ARG+ 140-6.245 1.764-12.608 1.00 0.00 ATOM 328 QH2 ARG+ 140-5. 932 1.219-12.012 1.00 0.00 ATOM 329 C ARG+ 140-7.172 5.984-5.912 1.00 0.00 ATOM 330 O ARG+ 140-8.010 5.293-5.335 1.00 0.00 ATOM 331 N MET 141-7. 445 7.187-6.403 1.00 0.00 ATOM 332 H MET 141-6.735 7.688-6.857 1.00 0.00 ATOM 333 CA MET 141-8.774 7.785-6.284 1.00 0.00 ATOM 334 HA MET 141-9.119 7.624-5.274 1.00 0. 00 ATOM 335 CB MET 141-8.697 9.291-6.551 1.00 0.00 ATOM 336 1HB MET 141-8.854 9.463-7.607 1.00 0.00 ATOM 337 2HB MET 141-7.714 9.644-6.280 1.00 0.00 ATOM 338 QB MET 141-8.284 9.553-6.944 1. 00 0.00 ATOM 339 CG MET 141-9.726 10.102-5.780 1.00 0.00 ATOM 340 1HG MET 141-9.441 10.121-4.738 1.00 0.00 ATOM 341 2HG MET 141-10.688 9.621-5.879 1. 00 0.00 ATOM 342 QG MET 141-10.064 9.871-5.309 1.00 0.00 ATOM 343 SD MET 141-9.867 11.798-6.373 1.00 0.00 ATOM 344 QE MET 141-7.843 12.491-6.132 1.00 0.00 ATOM 345 CE MET 141-8.182 12.374-6.171 1.00 0.00 ATOM 346 1HE MET 141-7.749 12.566-7.142 1.00 0.00 ATOM 347 2HE MET 141-7.601 11.621-5.661 1.00 0.00 ATOM 348 3HE MET 141-8.180 13.285-5.591 1.00 0.00 ATOM 349 C MET 141-9.764 7.129-7.252 1.00 0.00 ATOM 350 0 MET 141-10.683 7.777-7.756 1.00 0.00 ATOM 351 N ASP 142-9.567 5.845-7.498 1.00 0.00 ATOM 352 H ASP 142-8.820 5.390-7.062 1.00 0.00 ATOM 353 CA ASP 142-10.413 5.084-8.391 1.00 0.00 ATOM 354 HA ASP 142-11.078 5.767-8.895 1.00 0.00 ATOM 355 CB ASP 142-9.555 4.358-9.426 1.00 0.00 ATOM 356 1HB ASP 142-10.197 3.964-10.190 1.00 0.00 ATOM 357 2HB ASP 142-9.038 3.543-8.945 1.00 0.00 ATOM 358 QB ASP 142-9.617 3.753-9.568 1.00 0.00 ATOM 359 CG ASP 142-8.524 5.251-10.082 1.00 0.00 ATOM 360 OD1 ASP 142-7.502 5.563-9.432 1.00 0.00 ATOM 361 OD2 ASP 142-8.711 5.605-11.260 1.00 0.00 ATOM 362 C ASP 142-11.227 4.060-7.616 1.00 0.00

ATOM 363 0 ASP 142-12.456 4.038-7.689 1.00 0.00 ATOM 364 N VAL 143-10.527 3.202-6.881 1.00 0.00 ATOM 365 H VAL 143-9.551 3.270-6.872 1.00 0.00 ATOM 366 CA VAL 143-11.173 2.152-6.106 1.00 0.00 ATOM 367 HA VAL 143-12.123 1.934-6.574 1.00 0.00 ATOM 368 CB VAL 143-10.324 0.859-6.104 1.00 0.00 ATOM 369 HB VAL 143-9. 699 0.864-5.220 1.00 0.00 ATOM 370 QG1 VAL 143-11. 420-0.666-6.032 1.00 0.00 ATOM 371 QG2 VAL 143-9.202 0.782-7.615 1.00 0.00 ATOM 372 CG1 VAL 143-11.212-0.374-6.044 1.00 0.00 ATOM 373 1HG1 VAL 143-10.844-1.112-6.742 1.00 0.00 ATOM 374 2HG1 VAL 143-12.223-0.103-6.307 1.00 0.00 ATOM 375 3HG1 VAL 143-11.194-0.783-5.045 1.00 0.00 ATOM 376 CG2 VAL 143-9.417 0.797-7.326 1.00 0.00 ATOM 377 1HG2 VAL 143-9.742 1.527-8.053 1.00 0.00 ATOM 378 2HG2 VAL 143-9.466-0.191-7.760 1.00 0.00 ATOM 379 3HG2 VAL 143-8.400 1.010-7.030 1.00 0.00 ATOM 380 QQG VAL 143-10.311 0.058-6.823 1.00 0.00 ATOM 381 C VAL 143-11.425 2.609-4.666 1.00 0.00 ATOM 382 0VAL 143-10.754 3.510-4.165 1.00 0.00 ATOM 383 N CYS 144-12.410 1.995-4. 012 1.00 0.00 ATOM 384 H CYS 144-12.918 1.291-4.468 1.00 0.00 ATOM 385 CA CYS 144-12.764 2.351-2.637 1.00 0.00 ATOM 386 HA CYS 144-11.911 2.836-2.179 1.00 0.00 ATOM 387 CB CYS 144-13.951 3.316-2.633 1.00 0.00 ATOM 388 1HB CYS 144-14. 175 3.590-1.614 1.00 0.00 ATOM 389 2HB CYS 144-14.808 2.815-3.059 1.00 0.00 ATOM 390 QB CYS 144-14.491 3.202-2.337 1.00 0.00 ATOM 391 SG CYS 144-13.686 4.851-3.579 1.00 0.00 ATOM 392 C CYS 144-13.126 1.119-1.823 1.00 0.00 ATOM 393 O CYS 144-14.301 0.768-1.715 1.00 0.00 ATOM 394 N GLU 145-12.127 0.463-1.253 1.00 0.00 ATOM 395 H GLU 145-11.207 0.778-1.368 1.00 0.00 ATOM 396 CA GLU 145-12.365-0.727-0.466 1.00 0.00 ATOM 397 HA GLU 145-13.414-0.961-0.550 1.00 0.00 ATOM 398 CB GLU 145-11.575-1.887-1.038 1.00 0.00 ATOM 399 1HB GLU 145-11.282-2.546-0.237 1.00 0.00 ATOM 400 2HB GLU 145-10.686-1.502-1.522 1.00 0.00 ATOM 401 QB GLU 145-10.984-2.024-0.880 1.00 0.00 ATOM 402 CG GLU 145-12.388-2.681-2.038 1.00 0.00 ATOM 403 1HG GLU 145-11.830-3.556-2.335 1.00 0.00 ATOM 404 2HG GLU 145-12.586-2.063-2. 902 1.00 0.00 ATOM 405 QG GLU 145-12.208-2.810-2.619 1.00 0.00 ATOM 406 CD GLU 145-13.703-3.121-1.435 1.00 0.00 ATOM 407 OE1 GLU 145-14.751-2.568-1.814 1.00 0.00 ATOM 408 OE2 GLU 145-13.682-3.984-0.534 1.00 0.00 ATOM 409 C GLU 145-12.035-0.539 1.000 1.00 0.00 ATOM 410 0GLU 145-11.606 0.531 1.430 1.00 0.00 ATOM 411 N THR 146-12.267-1.600 1.752 1.00 0.00 ATOM 412 H THR 146-12.622-2.409 1.327 1.00 0.00 ATOM 413 CA THR 146-12.037-1.612 3.184 1.00 0.00 ATOM 414 HA THR 146-12.396-0.678 3.593 1.00 0.00 ATOM 415 CB THR 146-12.832-2.769 3.792 1.00 0.00 ATOM 416 HB THR 146-12.198-3.644 3.826 1.00 0.00 ATOM 417 QG2 THR 146-13.440-2.435 5.533 1.00 0.00 ATOM 418 OG1 THR 146-13.964-3.071 2.984 1.00 0.00 ATOM 419 1HG THR 146-14.096-4.026 2.961 1.00 0.00 ATOM 420 CG2 THR 146-13.323-2.501 5.197 1.00 0.00 ATOM 421 1HG2 THR 146-13.341-1.434 5.377 1.00 0.00 ATOM 422 2HG2 THR 146-12.661-2.972 5.909 1.00 0.00 ATOM 423 3HG2 THR 146-14.319-2.900 5.315 1.00 0.00 ATOM 424 C THR 146-10.547-1.755 3.490 1.00 0.00 ATOM 425 O THR 146-9.749-2.072 2.602 1.00 0.00 ATOM 426 N HIS+ 147-10.184-1.523 4.749 1.00 0.00 ATOM 427 H HIS+ 147-10.876-1.275 5.402 1.00 0.00 ATOM 428 CA HIS+ 147-8.794-1.621 5.200 1.00 0.00 ATOM 429 HA HIS+ 147-8.229-0.843 4.710 1.00 0.00 ATOM 430 CB HIS+ 147-8.727-1.405 6.714 1.00 0.00 ATOM 431 1HB HIS+ 147-8.681-2.367 7.205 1.00 0.00 ATOM 432 2HB HIS+ 147-9. 618-0. 887 7.037 1.00 0.00 ATOM 433 QB HIS+ 147-9.149-1.627 7.121 1.00 0.00 ATOM 434 CG HIS+ 147-7.545-0.604 7.160 1.00 0.00

ATOM 435 ND1 HIS+ 147-7.616 0.742 7.448 1.00 0.00 ATOM 436 CD2 HIS+ 147-6.258-0.967 7.375 1.00 0.00 ATOM 437 1HD HIS+ 147-8. 424 1.303 7.384 1.00 0.00 ATOM 438 CE1 HIS+ 147-6.423 1.174 7.821 1.00 0.00 ATOM 439 NE2 HIS+ 147-5.581 0.156 7.787 1.00 0.00 ATOM 440 2HD HIS+ 147-5.837-1.954 7.233 1.00 0.00 ATOM 441 1HE HIS+ 147-6.179 2.188 8.103 1.00 0.00 ATOM 442 2HE HIS+ 147-4.606 0.232 7.865 1.00 0.00 ATOM 443 C HIS+ 147-8.179-2.975 4.851 1.00 0.00 ATOM 444 O HIS+ 147-6.987-3.070 4.561 1.00 0.00 ATOM 445 N LEU 148-8.998-4.018 4.894 1.00 0.00 ATOM 446 H LEU 148-9.934-3.876 5.140 1.00 0.00 ATOM 447 CA LEU 148-8.544-5.369 4.599 1.00 0.00 ATOM 448 HA LEU 148-7.657-5.551 5.187 1.00 0.00 ATOM 449 CB LEU 148-9.620-6.380 5.007 1.00 0.00 ATOM 450 1HB LEU 148-10. 558-6.073 4.569 1.00 0.00 ATOM 451 2HB LEU 148-9.719-6.354 6.083 1.00 0.00 ATOM 452 QB LEU 148-10.138-6.214 5.326 1.00 0.00 ATOM 453 CG LEU 148-9.347-7.824 4.586 1.00 0.00 ATOM 454 HG LEU 148-8.923-7.824 3.593 1.00 0.00 ATOM 455 QD1 LEU 148-8. 108-8.631 5.746 1.00 0.00 ATOM 456 QD2 LEU 148-10.943-8.816 4.538 1.00 0.00 ATOM 457 CD1 LEU 148-8.346-8.476 5.524 1.00 0.00 ATOM 458 1HD1 LEU 148-8.684-9.470 5.777 1.00 0.00 ATOM 459 2HD1 LEU 148-8.257-7.886 6.424 1.00 0. 00 ATOM 460 3HD1 LEU 148-7.383-8.537 5.037 1.00 0.00 ATOM 461 CD2 LEU 148-10.638-8.625 4.548 1.00 0.00 ATOM 462 1HD2 LEU 148-10.437-9.612 4.158 1.00 0.00 ATOM 463 2HD2 LEU 148-11.354-8.127 3.911 1.00 0.00 ATOM 464 3HD2 LEU 148-11.040-8.708 5.547 1.00 0.00 ATOM 465 QQD LEU 148-9.525-8.723 5.142 1.00 0.00 ATOM 466 C LEU 148-8.193-5.543 3.123 1.00 0.00 ATOM 467 O LEU 148-7.195-6.183 2.797 1.00 0.00 ATOM 468 N HIS+ 149-9.012-4.988 2.229 1.00 0.00 ATOM 469 H HIS+ 149-9.798-4.491 2.535 1.00 0.00 ATOM 470 CA HIS+ 149-8.754-5.124 0.797 1.00 0.00 ATOM 471 HA HIS+ 149-8.685-6.183 0.592 1.00 0.00 ATOM 472 CB HIS+ 149-9.881-4.545-0.055 1.00 0.00 ATOM 473 1HB HIS+ 149-9.510-3.687-0.599 1.00 0.00 ATOM 474 2HB HIS+ 149-10.700-4.234 0.577 1.00 0.00 ATOM 475 QB HIS+ 149-10.105-3.961-0.011 1.00 0.00 ATOM 476 CG HIS+ 149-10.399-5.534-1.056 1.00 0.00 ATOM 477 ND1 HIS+ 149-11.734-5.681-1.362 1.00 0.00 ATOM 478 CD2 HIS+ 149-9.740-6.438-1.822 1.00 0.00 ATOM 479 1HD HIS+ 149-12.479-5.145-0. 983 1.00 0.00 ATOM 480 CE1 HIS+ 149-11.875-6.632-2.269 1.00 0.00 ATOM 481 NE2 HIS+ 149-10. 679-7. 107-2.566 1.00 0.00 ATOM 482 2HD HIS+ 149-8.670-6.601-1.843 1.00 0.00 ATOM 483 1HE HIS+ 149-12.811-6.962-2.699 1.00 0.00 ATOM 484 2HE HIS+ 149-10.483-7.722-3.305 1.00 0.00 ATOM 485 C HIS+ 149-7.431-4.492 0.409 1.00 0.00 ATOM 486 O HIS+ 149-6.594-5.149-0.194 1.00 0.00 ATOM 487 N TRP 150-7.240-3.224 0.756 1.00 0.00 ATOM 488 H TRP 150-7. 948-2.743 1.238 1.00 0.00 ATOM 489 CA TRP 150-5.990-2.533 0.431 1.00 0.00 ATOM 490 HA TRP 150-5.863-2.558-0.642 1.00 0.00 ATOM 491 CB TRP 150-6.020-1.085 0.908 1.00 0.00 ATOM 492 1HB TRP 150-5.045-0. 645 0.746 1.00 0.00 ATOM 493 2HB TRP 150-6.240-1.069 1.964 1.00 0.00 ATOM 494 QB TRP 150-5.642-0.857 1.355 1.00 0.00 ATOM 495 CG TRP 150-7. 031-0.225 0.218 1.00 0.00 ATOM 496 CD1 TRP 150-7.525 0.958 0.677 1.00 0.00 ATOM 497 CD2 TRP 150-7.670-0.463-1.045 1.00 0.00 ATOM 498 CE3 TRP 150-7.599-1.480-2.002 1.00 0.00 ATOM 499 CE2 TRP 150-8. 534 0.620-1.278 1.00 0.00 ATOM 500 NE1 TRP 150-8.428 1.468-0.215 1.00 0.00 ATOM 501 HD TRP 150-7. 238 1.414 1.613 1.00 0.00 ATOM 502 3HE TRP 150-6. 950-2.330-1.865 1.00 0.00 ATOM 503 CZ3 TRP 150-8. 378-1.385-3.134 1.00 0.00 ATOM 504 CZ2 TRP 150-9. 315 0.715-2.421 1.00 0.00 ATOM 505 1HE TRP 150-8.919 2.308-0.108 1.00 0.00 ATOM 506 3HZ TRP 150-8. 340-2.164-3.879 1.00 0.00

ATOM 507 CH2 TRP 150-9. 225-0.295-3.334 1.00 0.00 ATOM 508 2HZ TRP 150-9.976 1.552-2.593 1.00 0.00 ATOM 509 HH TRP 150-9.818-0.262-4.235 1.00 0.00 ATOM 510 C TRP 150-4.810-3.242 1.055 1.00 0.00 ATOM 511 0 TRP 150-3.739-3.287 0.466 1.00 0.00 ATOM 512 N HIS+ 151-5.012-3.815 2.233 1.00 0.00 ATOM 513 H HIS+ 151-5.898-3.760 2.651 1.00 0.00 ATOM 514 CA HIS+ 151-3. 951-4.548 2.899 1.00 0.00 ATOM 515 HA HIS+ 151-3.106-3.886 3.011 1.00 0.00 ATOM 516 CB HIS+ 151-4. 416-5.033 4.282 1.00 0.00 ATOM 517 1HB HIS+ 151-5. 273-5.680 4.154 1.00 0.00 ATOM 518 2HB HIS+ 151-4. 706-4.178 4.873 1.00 0.00 ATOM 519 QB HIS+ 151-4.989-4.929 4.513 1.00 0.00 ATOM 520 CG HIS+ 151-3. 378-5.796 5.058 1.00 0.00 ATOM 521 ND1 HIS+ 151-3.021-5.482 6.351 1.00 0.00 ATOM 522 CD2 HIS+ 151-2.636-6.879 4.722 1.00 0.00 ATOM 523 1HD HIS+ 151-3.383-4.740 6.883 1.00 0.00 ATOM 524 CE1 HIS+ 151-2. 108-6.338 6.773 1.00 0.00 ATOM 525 NE2 HIS+ 151-1.858-7.198 5.805 1.00 0.00 ATOM 526 2HD HIS+ 151-2.643-7.384 3.763 1.00 0.00 ATOM 527 1HE HIS+ 151-1.632-6.327 7.744 1.00 0. 00 ATOM 528 2HE HIS+ 151-1.375-8.042 5.921 1.00 0.00 ATOM 529 C HIS+ 151-3. 547-5.727 2.026 1.00 0.00 ATOM 530 O HIS+ 151-2.363-5.974 1.810 1.00 0.00 ATOM 531 N THR 152-4.546-6.439 1.522 1.00 0.00 ATOM 532 H THR 152-5.468-6.182 1.729 1.00 0.00 ATOM 533 CA THR 152-4.308-7.585 0.665 1.00 0.00 ATOM 534 HA THR 152-3.590-8.222 1.161 1.00 0.00 ATOM 535 CB THR 152-5.605-8.371 0.449 1.00 0.00 ATOM 536 HB THR 152-6.214-7.847-0.274 1.00 0.00 ATOM 537 QG2 THR 152-5.324-10.110-0.191 1.00 0.00 ATOM 538 OG1 THR 152-6.335-8.477 1.662 1.00 0.00 ATOM 539 1HG THR 152-6.622-7.601 1.946 1.00 0.00 ATOM 540 CG2 THR 152-5.379-9.775-0.066 1.00 0.00 ATOM 541 1HG2 THR 152-4.927-9.731-1. 049 1.00 0.00 ATOM 542 2HG2 THR 152-6.324-10.293-0.129 1.00 0.00 ATOM 543 3HG2 THR 152-4.722-10.305 0.607 1.00 0.00 ATOM 544 C THR 152-3.718-7.148-0.670 1.00 0.00 ATOM 545 0 THR 152-2.712-7.694-1.090 1.00 0.00 ATOM 546 N VAL 153-4.334-6.153-1.318 1.00 0.00 ATOM 547 H VAL 153-5.131-5.738-0.917 1.00 0.00 ATOM 548 CA VAL 153-3. 838-5.652-2.604 1.00 0.00 ATOM 549 HA VAL 153-3.889-6.463-3.316 1.00 0. 00 ATOM 550 CB VAL 153-4.697-4.478-3.131 1.00 0.00 ATOM 551 HB VAL. 153-4.641-3.668-2.419 1.00 0.00 ATOM 552 QG1 VAL 153-4.046-3.858-4.784 1.00 0.00 ATOM 553 QG2 VAL 153-6.495-5.001-3.296 1.00 0.00 ATOM 554 CG1 VAL 153-4.171-3.976-4.467 1.00 0.00 ATOM 555 1HG1 VAL 153-3.690-4.789-4.992 1.00 0.00 ATOM 556 2HG1 VAL 153-3.457-3.183-4.299 1.00 0.00 ATOM 557 3HG1 VAL 153-4.993-3.602-5.059 1.00 0.00 ATOM 558 CG2 VAL 153-6.152-4.900-3.264 1.00 0.00 ATOM 559 1HG2 VAL 153-6.201-5.864-3.751 1.00 0.00 ATOM 560 2HG2 VAL 153-6.686-4.171-3.854 1.00 0.00 ATOM 561 3HG2 VAL 153-6. 598-4.969-2.283 1.00 0.00 ATOM 562 QQG VAL 153-5.270-4.430-4.040 1.00 0.00 ATOM 563 C VAL 153-2.390-5.214-2.476 1.00 0.00 ATOM 564 O VAL 153-1.542-5.556-3.299 1.00 0.00 ATOM 565 N ALA 154-2.111-4.473-1.423 1.00 0.00 ATOM 566 H ALA 154-2.835-4.245-0.795 1.00 0.00 ATOM 567 CA ALA 154-0.767-4.003-1.157 1.00 0.00 ATOM 568 HA ALA 154-0.426-3.432-2.008 1.00 0.00 ATOM 569 QB ALA 154-0.784-2.885 0.347 1. 00 o. oo ATOM 570 CB ALA 154-0.781-3.100 0.059 1.00 0.00 ATOM 571 1HB ALA 154-1.790-2.763 0.245 1.00 0.00 ATOM 572 2HB ALA 154-0.142-2.247-0.120 1.00 0.00 ATOM 573 3HB ALA 154-0.420-3.646 0.917 1. 00 0.00 ATOM 574 C ALA 154 0.179-5.174-0.923 1. 00 0. 00 ATOM 575 O ALA 154 1.259-5.249-1.513 1. 00 0.00 ATOM 576 N LYS+ 155-0.237-6.082-0.047 1. 00 0. 00 ATOM 577 H LYS+ 155-1.108-5.955 0.391 1.00 0.00 ATOM 578 CA LYS+ 155 0.560-7.253 0.295 1.00 0.00

ATOM 579 HA LYS+ 155 1.526-6.904 0.646 1.00 0.00 ATOM 580 CB LYS+ 155-0.120-8.057 1.410 1.00 0.00 ATOM 581 1HB LYS+ 155-1.126-8.298 1.093 1.00 0.00 ATOM 582 2HB LYS+ 155-0.173-7.448 2.298 1.00 0.00 ATOM 583 QB LYS+ 155-0.649-7.873 1.695 1.00 0.00 ATOM 584 CG LYS+ 155 0.590-9.359 1.759 1.00 0.00 ATOM 585 1HG LYS+ 155 1.162-9.686 0.901 1.00 0.00 ATOM 586 2HG LYS+ 155-0. 151-10.106 2.003 1.00 0.00 ATOM 587 QG LYS+ 155 0.506-9.896 1.452 1.00 0.00 ATOM 588 CD LYS+ 155 1.528-9.194 2.944 1.00 0.00 ATOM 589 1HD'LYS+ 155 0.938-9.066 3.840 1.00 0.00 ATOM 590 2HD LYS+ 155 2.141-8.319 2.785 1.00 0.00 ATOM 591 QD LYS+ 155 1.540-8.693 3.312 1.00 0.00 ATOM 592 CE LYS+ 155 2.430-10.410 3.109 1.00 0.00 ATOM 593 1HE LYS+ 155 3.275-10.310 2.441 1.00 0.00 ATOM 594 2HE LYS+ 155 1.869-11.295 2.843 1.00 0.00 ATOM 595 QE LYS+ 155 2.572-10.803 2.642 1.00 0.00 ATOM 596 NZ LYS+ 155 2.928-10.557 4.508 1.00 0.00 ATOM 597 1HZ LYS+ 155 3.224-9.633 4.887 1.00 0. 00 ATOM 598 2HZ LYS+ 155 3.742-11.205 4.532 1.00 0.00 ATOM 599 3HZ LYS+ 155 2.178-10.944 5.116 1.00 0.00 ATOM 600 QZ LYS+ 155 3.048-10.594 4.845 1.00 0.00 ATOM 601 C LYS+ 155 0.788-8.145-0.914 1.00 0.00 ATOM 602 O LYS+ 155 1.918-8.541-1.161 1.00 0.00 ATOM 603 N GLU 156-0.273-8.471-1.650 1.00 0.00 ATOM 604 H GLU 156-1.165-8.132-1.399 1.00 0.00 ATOM 605 CA GLU 156-0. 140-9.334-2.816 1.00 0.00 ATOM 606 HA GLU 156 0.330-10.246-2.476 1.00 0.00 ATOM 607 CB GLU 156-1.508-9.698-3.425 1.00 0.00 ATOM 608 1HB GLU 156-2.127-10.131-2.652 1.00 0.00 ATOM 609 2HB GLU 156-1.354-10.437-4.197 1.00 0.00 ATOM 610 QB GLU 156-1.740-10.284-3.425 1.00 0.00 ATOM 611 CG GLU 156-2.272-8.536-4.041 1.00 0.00 ATOM 612 1HG GLU 156-1.990-8.444-5.079 1.00 0.00 ATOM 613 2HG GLU 156-2.011-7.629-3.515 1.00 0.00 ATOM 614 QG GLU 156-2.000-8.037-4.297 1.00 0.00 ATOM 615 CD GLU 156-3.774-8.725-3.961 1.00 0.00 ATOM 616 OE1 GLU 156-4.222-9.611-3.202 1.00 0.00 ATOM 617 OE2 GLU 156-4.503-7.982-4.648 1.00 0.00 ATOM 618 C GLU 156 0.778-8.703-3.857 1.00 0.00 ATOM 619 O GLU 156 1.600-9.388-4.440 1.00 0.00 ATOM 620 N THR 157 0.662-7.395-4.068 1.00 0.00 ATOM 621 H THR 157-0.007-6.882-3.561 1.00 0.00 ATOM 622 CA THR 157 1.520-6.707-5.032 1.00 0.00 ATOM 623 HA THR 157 1.345-7.153-6.000 1.00 0.00 ATOM 624 CB THR 157 1.161-5.217-5.095 1.00 0.00 ATOM 625 HB THR 157 1.256-4.792-4.105 1.00 0.00 ATOM 626 QG2 THR 157 2.253-4.225-6.252 1.00 0.00 ATOM 627 OG1 THR 157-0.175-5.041-5.529 1.00 0.00 ATOM 628 1HG THR 157-0.785-5.360-4.845 1.00 0.00 ATOM 629 CG2 THR 157 2.043-4.415-6.029 1.00 0.00 ATOM 630 1HG2 THR 157 2.549-3.641-5.471 1.00 0.00 ATOM 631 2HG2 THR 157 1.435-3.964-6.800 1.00 0.00 ATOM 632 3HG2 THR 157 2.774-5.069-6.484 1.00 0.00 ATOM 633 C THR 157 3.000-6.889-4.673 1.00 0.00 ATOM 634 O THR 157 3.844-7.107-5.546 1.00 0.00 ATOM 635 N CYS 158 3.309-6.803-3.387 1.00 0.00 ATOM 636 H CYS 158 2.595-6.627-2.735 1.00 0.00 ATOM 637 CA CYS 158 4.682-6.964-2.921 1.00 0.00 ATOM 638 HA CYS 158 5.332-6.487-3.640 1.00 0.00 ATOM 639 CB CYS 158 4.858-6.272-1.569 1.00 0.00 ATOM 640 1HB CYS 158 5.708-6.689-1.062 1.00 0.00 ATOM 641 2HB CYS 158 3.978-6.447-0.972 1.00 0.00 ATOM 642 QB CYS 158 4.843-6.568-1.017 1.00 0.00 ATOM 643 SG CYS 158 5.096-4.461-1.694 1.00 0.00 ATOM 644 C CYS 158 5.069-8.444-2.828 1.00 0.00 ATOM 645 O CYS 158 6.142-8.838-3.282 1.00 0.00 ATOM 646 N SER 159 4.195-9.254-2.233 1.00 0.00 ATOM 647 H SER 159 3.360-8.878-1.884 1.00 0.00 ATOM 648 CA SER 159 4.444-10.687-2.064 1.00 0.00 ATOM 649 HA SER 159 5.412-10.787-1.595 1.00 0.00 ATOM 650 CB SER 159 3.395-11.306-1.140 1.00 0.00

ATOM 651 1HB SER 159 3.309-12.362-1.355 1.00 0.00 ATOM 652 2HB SER 159 2.441-10.826-1.308 1.00 0.00 ATOM 653 QB SER 159 2.875-11.594-1.332 1.00 0.00 ATOM 654 OG SER 159 3.764-11.142 0.226 1.00 0.00 ATOM 655 HG SER 159 4.663-11.468 0.346 1.00 0.00 ATOM 656 C SER 159 4.487-11.440-3.397 1.00 0.00 ATOM 657 O SER 159 5.176-12.452-3.504 1.00 0.00 ATOM 658 N GLU 160 3.778-10.941-4.415 1.00 0.00 ATOM 659 H GLU 160 3.252-10.122-4.284 1.00 0.00 ATOM 660 CA GLU 160 3.786-11.581-5.733 1.00 0.00 ATOM 661 HA GLU 160 3.645-12.643-5.587 1.00 0.00 ATOM 662 CB GLU 160 2.661-11.039-6.621 1.00 0.00 ATOM 663 1HB GLU 160 3.023-10.175-7.157 1.00 0.00 ATOM 664 2HB GLU 160 1.835-10.740-5.990 1.00 0.00 ATOM 665 QB GLU 160 2.429-10.458-6.574 1.00 0.00 ATOM 666 CG GLU 160 2.139-12.047-7.635 1.00 0.00 ATOM 667 1HG GLU 160 2.967-12.639-7.993 1.00 0.00 ATOM 668 2HG GLU 160 1.697-11.512-8.460 1.00 0.00 ATOM 669 QG GLU 160 2.332-12.076-8.227 1.00 0.00 ATOM 670 CD GLU 160 1.095-12.979-7.053 1.00 0.00 ATOM 671 OE1 GLU 160 0.222-13.438-7.817 1.00 0.00 ATOM 672 OE2 GLU 160 1.154-13.253-5.836 1.00 0.00 ATOM 673 C GLU 160 5.138-11.349-6.396 1.00 0.00 ATOM 674 O GLU 160 5.445-11.883-7.468 1.00 0.00 ATOM 675 N LYS+ 161 5.958-10.558-5.730 1.00 0.00 ATOM 676 H LYS+ 161 5.661-10.180-4.875 1.00 0.00 ATOM 677 CA LYS+ 161 7.284-10.261-6.200 1.00 0.00 ATOM 678 HA LYS+ 161 7.426-10.777-7.136 1.00 0.00 ATOM 679 CB LYS+ 161 7.462-8.757-6.416 1.00 0.00 ATOM 680 1HB LYS+ 161 7.867-8.321-5.513 1.00 0.00 ATOM 681 2HB LYS+ 161 6.497-8.315-6.618 1.00 0.00 ATOM 682 QB LYS+ 161 7.182-8.318-6.066 1.00 0.00 ATOM 683 CG LYS+ 161 8.397-8.424-7.571 1.00 0.00 ATOM 684 1HG LYS+ 161 9.238-9.103-7.550 1.00 0.00 ATOM 685 2HG LYS+ 161 8.749-7.409-7.457 1.00 0.00 ATOM 686 QG LYS+ 161 8.994-8.256-7.504 1.00 0.00 ATOM 687 CD LYS+ 161 7.685-8.553-8.913 1.00 0.00 ATOM 688 1HD LYS+ 161 7.907-7.679-9.510 1.00 0.00 ATOM 689 2HD LYS+ 161 6.620-8.607-8.740 1.00 0.00 ATOM 690 QD LYS+ 161 7.264-8.143-9.125 1.00 0.00 ATOM 691 CE LYS+ 161 8.126-9.798-9.677 1.00 0.00 ATOM 692 1HE LYS+ 161 9.203-9.872-9.625 1.00 0.00 ATOM 693 2HE LYS+ 161 7.825-9.693-10.710 1.00 0.00 ATOM 694 QE LYS+ 161 8.514-9.783-10.168 1.00 0.00 ATOM 695 NZ LYS+ 161 7.524-11.051-9.124 1.00 0.00 ATOM 696 1HZ LYS+ 161 6.635-10.838-8.613 1.00 0.00 ATOM 697 2HZ LYS+ 161 8.184-11.507-8.462 1.00 0.00 ATOM 698 3HZ LYS+ 161 7.311-11.720-9.892 1.00 0.00 ATOM 699 QZ LYS+ 161 7.377-11.355-8.989 1.00 0.00 ATOM 700 C LYS+ 161 8.277-10.804-5.184 1.00 0.00 ATOM 701 O LYS+ 161 8.101-11.908-4.680 1.00 0.00 ATOM 702 N SER 162 9.311-10.048-4.881 1.00 0.00 ATOM 703 H SER 162 9.416-9.177-5.305 1.00 0.00 ATOM 704 CA SER 162 10.298-10.495-3.920 1.00 0.00 ATOM 705 HA SER 162 10.027-11.493-3.612 1.00 0.00 ATOM 706 CB SER 162 11.684-10.534-4.565 1.00 0.00 ATOM 707 1HB SER 162 12.058-11.548-4.545 1.00 0.00 ATOM 708 2HB SER 162 12.353-9.895-4.006 1.00 0.00 ATOM 709 QB SER 162 12.206-10.722-4.276 1.00 0.00 ATOM 710 OG SER 162 11.636-10.085-5.917 1.00 0.00 ATOM 711 HG SER 162 12.507-10.184-6.313 1.00 0.00 ATOM 712 C SER 162 10.319-9.591-2.692 1.00 0.00 ATOM 713 O SER 162 11.387-9.208-2.224 1.00 0.00 ATOM 714 N THR 163 9.144-9.237-2.167 1.00 0.00 ATOM 715 H THR 163 8.310-9.558-2.574 1.00 0.00 ATOM 716 CA THR 163 9.083-8.380-0.989 1.00 0.00 ATOM 717 HA THR 163 9.993-8.539-0.427 1.00 0.00 ATOM 718 CB THR 163 9.005-6.898-1.373 1.00 0.00 ATOM 719 HB THR 163 8.825-6.331-0.466 1.00 0.00 ATOM 720 QG2 THR 163 10.565-6.225-2.164 1.00 0.00 ATOM 721 OG1 THR 163 7.940-6.657-2.275 1.00 0.00 ATOM 722 1HG THR 163 7.699-5.726-2.252 1.00 0. 00

ATOM 723 CG2 THR 163 10.264-6.353-2.012 1.00 0.00 ATOM 724 1HG2 THR 163 10.082-6.157-3.058 1.00 0.00 ATOM 725 2HG2 THR 163 11.058-7.081-1.917 1.00 0.00 ATOM 726 3HG2 THR 163 10.554-5.437-1.517 1.00 0.00 ATOM 727 C THR 163 7.900-8.735-0.088 1.00 0.00 ATOM 728 O THR 163 6.929-9.358-0.511 1.00 0.00 ATOM 729 N ASN 164 7.995-8.320 1.166 1.00 0.00 ATOM 730 H ASN 164 8.803-7.830 1.440 1.00 0.00 ATOM 731 CA ASN 164 6.943-8.575 2.156 1.00 0.00 ATOM 732 HA ASN 164 6.108-9.033 1.640 1.00 0.00 ATOM 733 CB ASN 164 7.450-9.530 3.247 1.00 0.00 ATOM 734 1HB ASN 164 7.281-10.548 2.930 1.00 0.00 ATOM 735 2HB ASN 164 6.903-9.347 4.160 1.00 0. 00 ATOM 736 QB ASN 164 7.092-9.948 3.545 1.00 0.00 ATOM 737 CG ASN 164 8.932-9.361 3.540 1.00 0.00 ATOM 738 OD1 ASN 164 9.628-10.327 3.817 1.00 0.00 ATOM 739 ND2 ASN 164 9.412-8.125 3.503 1.00 0.00 ATOM 740 1HD2 ASN 164 8.788-7.395 3.311 1.00 0.00 ATOM 741 2HD2 ASN 164 10.373-7.998 3.615 1.00 0.00 ATOM 742 QD2 ASN 164 9.581-7.697 3.463 1.00 0.00 ATOM 743 C ASN 164 6.477-7.274 2.808 1.00 0.00 ATOM 744 O ASN 164 7.296-6.466 3.241 1.00 0.00 ATOM 745 N LEU 165 5. 164-7.071 2.875 1.00 0.00 ATOM 746 H LEU 165 4.561-7.746 2.512 1.00 0.00 ATOM 747 CA LEU 165 4.601-5.860 3.480 1.00 0.00 ATOM 748 HA LEU 165 5.065-5.000 3.017 1.00 0.00 ATOM 749 CB LEU 165 3.091-5.788 3.264 1.00 0.00 ATOM 750 1HB LEU 165 2.611-5.713 4.230 1.00 0.00 ATOM 751 2HB LEU 165 2.766-6.699 2.786 1.00 0.00 ATOM 752 QB LEU 165 2.689-6.206 3.508 1.00 0.00 ATOM 753 CG LEU 165 2.625-4.614 2.428 1.00 0.00 ATOM 754 HG LEU 165 3.099-3.710 2.786 1.00 0.00 ATOM 755 QD1 LEU 165 3.120-4.862 0.641 1.00 0.00 ATOM 756 QD2 LEU 165 0.766-4.402 2.588 1.00 0.00 ATOM 757 CD1 LEU 165 3.026-4.815 0.986 1.00 0.00 ATOM 758 1HD1 LEU 165 3.800-4.109 0.725 1.00 0.00 ATOM 759 2HD1 LEU 165 2.166-4.656 0.349 1.00 0.00 ATOM 760 3HD1 LEU 165 3.393-5.820 0.849 1.00 0.00 ATOM 761 CD2 LEU 165 1.123-4.443 2.558 1.00 0.00 ATOM 762 1HD2 LEU 165 0.832-3.491 2.140 1.00 0.00 ATOM 763 2HD2 LEU 165 0.844-4.478 3.601 1.00 0.00 ATOM 764 3HD2 LEU 165 0.622-5.238 2.024 1.00 0.00 ATOM 765 QQD LEU 165 1.943-4.632 1.614 1.00 0.00 ATOM 766 C LEU 165 4.876-5.808 4.967 1.00 0.00 ATOM 767 O LEU 165 4.509-6.721 5.707 1.00 0.00 ATOM 768 N HIS+ 166 5.505-4.728 5.390 1.00 0.00 ATOM 769 H HIS+ 166 5.760-4.036 4.741 1.00 0.00 ATOM 770 CA HIS+ 166 5.819-4.524 6.787 1.00 0.00 ATOM 771 HA HIS+ 166 5.519-5.408 7.329 1.00 0.00 ATOM 772 CB HIS+ 166 7.328-4.313 6.962 1.00 0.00 ATOM 773 1HB HIS+ 166 7.625-3.428 6. 415 1.00 0.00 ATOM 774 2HB HIS+ 166 7.854-5.167 6.565 1.00 0.00 ATOM 775 QB HIS+ 166 7.740-4.298 6.490 1.00 0.00 ATOM 776 CG HIS+ 166 7.754-4.134 8.385 1.00 0.00 ATOM 777 ND1 HIS+ 166 7.753-5.153 9.313 1.00 0.00 ATOM 778 CD2 HIS+ 166 8.185-3.034 9.037 1.00 0.00 ATOM 779 1HD HIS+ 166 7.486-6. 081 9.145 1.00 0.00 ATOM 780 CE1 HIS+ 166 8.165-4.681 10.478 1.00 0.00 ATOM 781 NE2 HIS+ 166 8.434-3.394 10.336 1.00 0.00 ATOM 782 2HD HIS+ 166 8.294-2.040 8.613 1.00 0. 00 ATOM 783 1HE HIS+ 166 8.264-5.251 11.390 1.00 0.00 ATOM 784 2HE HIS+ 166 8.555-2.762 11.075 1.00 0.00 ATOM 785 C HIS+ 166 5.038-3.324 7.325 1.00 0.00 ATOM 786 0 HIS+ 166 4.362-3.424 8.349 1.00 0. 00 ATOM 787 N ASP 167 5.131-2.196 6.622 1.00 0.00 ATOM 788 H ASP 167 5.683-2.183 5.810 1.00 0.00 ATOM 789 CA ASP 167 4.432-0.975 7.036 1. 00 0. 00 ATOM 790 HA ASP 167 3.909-1.195 7.955 1.00 0.00 ATOM 791 CB ASP 167 5.419 0.173 7.294 1. 00 0. 00 ATOM 792 1HB ASP 167 5.000 0.833 8.039 1. 00 0. 00 ATOM 793 2HB ASP 167 5.562 0.724 6.378 1. oo o. oo ATOM 794 QB ASP 167 5.281 0.778 7.208 1. 00 0. 00

ATOM 795 CG ASP 167 6. 776-0.293 7.781 1.00 0.00 ATOM 796 OD1 ASP 167 7.605-0.703 6.939 1.00 0.00 ATOM 797 OD2 ASP 167 7.015-0.242 9.005 1.00 0.00 ATOM 798 C ASP 167 3.414-0.530 5.987 1.00 0.00 ATOM 799 O ASP 167 3.731 0.240 5.085 1.00 0.00 ATOM 800 N TYR 168 2.193-1.020 6.113 1.00 0.00 ATOM 801 H TYR 168 2.003-1.628 6.858 1.00 0.00 ATOM 802 CA TYR 168 1.111-0.676 5.187 1.00 0.00 ATOM 803 HA TYR 168 1.549-0.404 4.229 1.00 0.00 ATOM 804 CB TYR 168 0.188-1.883 4.996 1.00 0.00 ATOM 805 1HB TYR 168 0.591-2.519 4.223 1.00 0.00 ATOM 806 2HB TYR 168-0. 790-1.535 4.698 1.00 0.00 ATOM 807 QB TYR 168-0.099-2.027 4.460 1.00 0.00 ATOM 808 QD TYR 168 0.008-2.810 6.398 1.00 0.00 ATOM 809 QE TYR 168-0. 243-4.144 8.446 1.00 0.00 ATOM 810 QR TYR 168-0. 117-3. 477 7.422 1.00 0.00 ATOM 811 CG TYR 168 0.025-2.715 6.251 1.00 0.00 ATOM 812 CD1 TYR 168-0.975-2.429 7.173 1.00 0.00 ATOM 813 1HD TYR 168-1.647-1.606 6.979 1.00 0.00 ATOM 814 CE1 TYR 168-1.119-3.176 8.325 1.00 0.00 ATOM 815 1HE TYR 168-1.902-2.937 9.029 1.00 0.00 ATOM 816 CZ TYR 168-0.259-4.224 8.569 1.00 0.00 ATOM 817 CE2 TYR 168 0.741-4.530 7.671 1.00 0.00 ATOM 818 2HE TYR 168 1.416-5.351 7.864 1.00 0.00 ATOM 819 CD2 TYR 168 0.879-3.778 6.521 1.00 0.00 ATOM 820 2HD TYR 168 1.663-4.014 5.817 1.00 0.00 ATOM 821 OH TYR 168-0.401-4.971 9.712 1.00 0.00 ATOM 822 HH TYR 168 0.274-4.716 10.348 1.00 0.00 ATOM 823 C TYR 168 0.302 0.510 5.705 1.00 0.00 ATOM 824 O TYR 168 0.175 0.710 6.913 1.00 0.00 ATOM 825 N GLY 169-0.260 1.273 4.785 1.00 0.00 ATOM 826 H GLY 169-0.135 1.054 3.837 1.00 0.00 ATOM 827 CA GLY 169-1.066 2.417 5.146 1.00 0.00 ATOM 828 1HA GLY 169-0.442 3.299 5.167 1.00 0.00 ATOM 829 2HA GLY 169-1.491 2.256 6.126 1.00 0.00 ATOM 830 QA GLY 169-0.966 2.777 5.646 1.00 0.00 ATOM 831 C GLY 169-2.176 2.623 4.146 1.00 0.00 ATOM 832 O GLY 169-2.098 2.118 3.027 1.00 0.00 ATOM 833 N MET 170-3.209 3.347 4.534 1.00 0.00 ATOM 834 H MET 170-3.221 3.724 5.438 1.00 0.00 ATOM 835 CA MET 170-4.331 3.600 3.642 1.00 0.00 ATOM 836 HA MET 170-3.993 3.423 2.624 1.00 0.00 ATOM 837 CB MET 170-5.500 2.661 3.960 1.00 0.00 ATOM 838 1HB MET 170-6.390 3.042 3.481 1.00 0.00 ATOM 839 2HB MET 170-5.656 2.649 5.028 1.00 0.00 ATOM 840 QB MET 170-6.023 2.845 4.254 1.00 0.00 ATOM 841 CG MET 170-5.281 1.231 3.493 1.00 0.00 ATOM 842 1HG MET 170-4.628 1.245 2.631 1.00 0.00 ATOM 843 2HG MET 170-6.235 0.809 3.212 1.00 0.00 ATOM 844 QG MET 170-5.431 1.027 2.921 1.00 0.00 ATOM 845 SD MET 170-4.540 0.189 4.764 1.00 0.00 ATOM 846 QE MET 170-3.346-1.142 3.571 1.00 0.00 ATOM 847 CE MET 170-3.546-0.919 3.772 1.00 0.00 ATOM 848 1HE MET 170-2.823-1.415 4.401 1.00 0.00 ATOM 849 2HE MET 170-3.032-0.355 3.007 1.00 0.00 ATOM 850 3HE MET 170-4.184-1.657 3.307 1.00 0.00 ATOM 851 C MET 170-4.775 5.048 3.769 1.00 0.00 ATOM 852 0 MET 170-5.156 5.498 4.849 1.00 0.00 ATOM 853 N LEU 171-4.709 5.775 2.668 1.00 0.00 ATOM 854 H LEU 171-4.388 5.357 1.840 1.00 0.00 ATOM 855 CA LEU 171-5.087 7.179 2.659 1.00 0.00 ATOM 856 HA LEU 171-5.345 7.455 3.671 1.00 0.00 ATOM 857 CB LEU 171-3.905 8.037 2.198 1.00 0.00 ATOM 858 1HB LEU 171-3.129 7.974 2.948 1.00 0.00 ATOM 859 2HB LEU 171-4.235 9.063 2.133 1.00 0.00 ATOM 860 QB LEU 171-3.682 8.518 2.540 1.00 0.00 ATOM 861 CG LEU 171-3.298 7.640 0.850 1.00 0. 00 ATOM 862 HG LEU 171-4.030 7.090 0.279 1.00 0.00 ATOM 863 QD1 LEU 171-2.824 9.165-0.130 1.00 0.00 ATOM 864 QD2 LEU 171-1.794 6.539 1.090 1.00 0. 00 ATOM 865 CD1 LEU 171-2. 917 8.873 0.059 1.00 0.00 ATOM 866 1HD1 LEU 171-2.517 9.620 0.728 1.00 0.00

ATOM 867 2HD1 LEU 171-3.789 9.265-0.442 1.00 0.00 ATOM 868 3HD1 LEU 171-2.167 8.611-0.674 1.00 0.00 ATOM 869 CD2 LEU 171-2.083 6.749 1.044 1.00 0.00 ATOM 870 1HD2 LEU 171-1.267 7.117 0.440 1.00 0.00 ATOM 871 2HD2 LEU 171-2.324 5.740 0.747 1.00 0.00 ATOM 872 3HD2 LEU 171-1.791 6.759 2.085 1.00 0.00 ATOM 873 QQD LEU 171-2.309 7.852 0.480 1.00 0.00 ATOM 874 C LEU 171-6. 296 7.419 1.761 1.00 0.00 ATOM 875 O LEU 171-6.930 6.468 1.305 1.00 0.00 ATOM 876 N LEU 172-6. 594 8.702 1.517 1.00 0.00 ATOM 877 H LEU 172-6.030 9.394 1.921 1.00 0.00 ATOM 878 CA LEU 172-7.721 9.122 0.672 1.00 0.00 ATOM 879 HA LEU 172-7.894 10.171 0.859 1.00 0.00 ATOM 880 CB LEU 172-7.389 8.939-0.815 1.00 0.00 ATOM 881 1HB LEU 172-8.236 8.461-1.287 1.00 0.00 ATOM 882 2HB LEU 172-6.538 8.279-0.900 1.00 0.00 ATOM 883 QB LEU 172-7.387 8.370-1.094 1.00 0.00 ATOM 884 CG LEU 172-7.086 10.230-1.580 1.00 0.00 ATOM 885 HG LEU 172-7.888 10.935-1.417 1.00 0.00 ATOM 886 QD1 LEU 172-5.491 11.013-0.966 1.00 0.00 ATOM 887 QD2 LEU 172-6.976 9.890-3.426 1.00 0.00 ATOM 888 CD1 LEU 172-5.797 10.863-1.083 1.00 0.00 ATOM 889 1HD1 LEU 172-5.986 11.888-0.800 1.00 0.00 ATOM 890 2HD1 LEU 172-5.057 10.838-1.870 1.00 0.00 ATOM 891 3HD1 LEU 172-5.432 10.314-0.228 1.00 0.00 ATOM 892 CD2 LEU 172-6.998 9.955-3.072 1.00 0.00 ATOM 893 1HD2 LEU 172-6.008 10.204-3.426 1.00 0.00 ATOM 894 2HD2 LEU 172-7.727 10.557-3. 593 1.00 0.00 ATOM 895 3HD2 LEU 172-7.193 8.910-3.259 1.00 0.00 ATOM 896 QQD LEU 172-6.233 10.452-2.196 1.00 0.00 ATOM 897 C LEU 172-8.999 8.356 0.999 1.00 0.00 ATOM 898 O LEU 172-9.355 7.418 0.296 1.00 0.00 ATOM 899 N PRO 173-9.716 8.740 2.062 1.00 0.00 ATOM 900 CD PRO 173-9.391 9.854 2.969 1.00 0.00 ATOM 901 CA PRO 173-10.955 8.059 2.439 1.00 0.00 ATOM 902 HA PRO 173-10.774 7.012 2.644 1.00 0.00 ATOM 903 CB PRO 173-11.393 8.771 3.723 1.00 0.00 ATOM 904 1HB PRO 173-11.108 8.180 4.581 1.00 0.00 ATOM 905 2HB PRO 173-12.465 8.904 3.713 1.00 0.00 ATOM 906 QB PRO 173-11.786 8.542 4.147 1.00 0.00 ATOM 907 CG PRO 173-10.682 10.084 3.706 1.00 0.00 ATOM 908 1HG PRO 173-10.483 10.406 4.718 1.00 0.00 ATOM 909 2HG PRO 173-11.282 10.819 3.190 1.00 0.00 ATOM 910 QG PRO 173-10.882 10.612 3.954 1.00 0.00 ATOM 911 1HD PRO 173-8.607 9.574 3.657 1.00 0.00 ATOM 912 2HD PRO 173-9.112 10.736 2.412 1.00 0.00 ATOM 913 QD PRO 173-8.859 10.155 3.034 1.00 0.00 ATOM 914 C PRO 173-12.030 8.179 1.360 1.00 0.00 ATOM 915 O PRO 173-12.113 9.183 0. 652 1.00 0.00 ATOM 916 N CYS 174-12.845 7.145 1.237 1.00 0.00 ATOM 917 H CYS 174-12.725 6.371 1.830 1.00 0.00 ATOM 918 CA CYS 174-13.913 7.123 0.246 1.00 0.00 ATOM 919 HA CYS 174-13.920 8.079-0.256 1.00 0.00 ATOM 920 CB CYS 174-13.660 6.021-0.779 1.00 0.00 ATOM 921 1HB CYS 174-14.025 5.085-0.384 1.00 0.00 ATOM 922 2HB CYS 174-12.598 5.942-0.956 1.00 0.00 ATOM 923 QB CYS 174-13.311 5.513-0.670 1.00 0.00 ATOM 924 SG CYS 174-14.469 6.297-2.389 1.00 0.00 ATOM 925 C CYS 174-15.262 6.909 0.919 1.00 0.00 ATOM 926 O CYS 174-16.300 7.315 0.403 1.00 0.00 ATOM 927 N GLY 175-15.234 6.272 2.078 1.00 0.00 ATOM 928 H GLY 175-14.372 5.976 2.445 1.00 0.00 ATOM 929 CA GLY 175-16.451 6.016 2.820 1.00 0.00 ATOM 930 1HA GLY 175-16.884 5.088 2.482 1.00 0.00 ATOM 931 2HA GLY 175-17.150 6.820 2.645 1.00 0.00 ATOM 932 QA GLY 175-17.017 5.954 2.563 1.00 0.00 ATOM 933 C GLY 175-16.170 5.920 4.297 1.00 0.00 ATOM 934 O GLY 175-15.109 6.345 4.746 1.00 0.00 ATOM 935 N ILE 176-17.105 5.352 5. 050 1.00 0.00 ATOM 936 H ILE 176-17.925 5.024 4.629 1.00 0.00 ATOM 937 CA ILE 176-16.931 5.192 6.489 1.00 0.00 ATOM 938 HA ILE 176-16. 791 6.172 6.922 1.00 0.00

ATOM 939 CB ILE 176-18.169 4.538 7.138 1.00 0.00 ATOM 940 HB ILE 176-18.100 3.471 6.990 1.00 0.00 ATOM 941 QG2 ILE 176-18.196 4.872 8.990 1.00 0.00 ATOM 942 CG2 ILE 176-18.191 4.808 8.636 1.00 0.00 ATOM 943 1HG2 ILE 176-17.190 5.028 8.977 1.00 0.00 ATOM 944 2HG2 ILE 176-18.565 3.936 9.153 1.00 0.00 ATOM 945 3HG2 ILE 176-18.835 5.651 8.840 1.00 0.00 ATOM 946 CG1 ILE 176-19.456 5.053 6.483 1.00 0.00 ATOM 947 lHGl ILE 176-19. 479 4.736 5.452 1.00 0.00 ATOM 948 2HG1 ILE 176-19.464 6.132 6.524 1.00 0.00 ATOM 949 QG1 ILE 176-19. 471 5.434 5.988 1.00 0.00 ATOM 950 QD1 ILE 176-21.018 4.437 7.312 1.00 0.00 ATOM 951 CD1 ILE 176-20.719 4.555 7.153 1.00 0.00 ATOM 952 lHDl ILE 176-20.533 4.412 8.207 1.00 0.00 ATOM 953 2HD1 ILE 176-21. 017 3.617 6.708 1.00 0.00 ATOM 954 3HD1 ILE 176-21.506 5.283 7.022 1.00 0.00 ATOM 955 C ILE 176-15.694 4.340 6.776 1.00 0.00 ATOM 956 O ILE 176-14.828 4.729 7.556 1.00 0.00 ATOM 957 N ASP 177-15.615 3.189 6.112 1. 00 0.00 ATOM 958 H ASP 177-16.330 2.950 5.491 1.00 0.00 ATOM 959 CA ASP 177-14.477 2.286 6.261 1.00 0.00 ATOM 960 HA ASP 177-13.718 2.801 6.834 1.00 0.00 ATOM 961 CB ASP 177-14.881 1.008 7.005 1.00 0.00 ATOM 962 1HB ASP 177-15.390 0.346 6.321 1.00 0.00 ATOM 963 2HB ASP 177-15.546 1.264 7.815 1.00 0.00 ATOM 964 QB ASP 177-15.468 0.805 7.068 1.00 0.00 ATOM 965 CG ASP 177-13.685 0.272 7.583 1.00 0.00 ATOM 966 OD1 ASP 177-12.581 0.858 7.621 1.00 0.00 ATOM 967 OD2 ASP 177-13.850-0.896 7.991 1.00 0.00 ATOM 968 C ASP 177-13.904 1.935 4.889 1.00 0.00 ATOM 969 O ASP 177-13.412 0.829 4.657 1.00 0.00 ATOM 970 N LYS+ 178-13. 967 2.889 3.972 1.00 0.00 ATOM 971 H LYS+ 178-14.361 3.754 4.209 1.00 0.00 ATOM 972 CA LYS+ 178-13.444 2.682 2.629 1.00 0.00 ATOM 973 HA LYS+ 178-12.962 1.715 2.609 1.00 0.00 ATOM 974 CB LYS+ 178-14.557 2.715 1.574 1.00 0.00 ATOM 975 1HB LYS+ 178-14.124 2.479 0.612 1.00 0.00 ATOM 976 2HB LYS+ 178-14.963 3.712 1.536 1.00 0.00 ATOM 977 QB LYS+ 178-14.543 3.095 1.074 1.00 0.00 ATOM 978 CG LYS+ 178-15.702 1.738 1.836 1.00 0.00 ATOM 979 1HG LYS+ 178-16.460 1.876 1.078 1.00 0.00 ATOM 980 2HG LYS+ 178-16.123 1.947 2.809 1.00 0.00 ATOM 981 QG LYS+ 178-16.291 1.911 1.943 1.00 0.00 ATOM 982 CD LYS+ 178-15.233 0.287 1.808 1.00 0.00 ATOM 983 1HD LYS+ 178-15.457-0.170 2.762 1.00 0.00 ATOM 984 2HD LYS+ 178-14. 165 0.269 1.643 1.00 0.00 ATOM 985 QD LYS+ 178-14.811 0.049 2. 202 1.00 0.00 ATOM 986 CE LYS+ 178-15.916-0.512 0.702 1.00 0.00 ATOM 987 1HE LYS+ 178-15. 605-0. 115-0. 256 1. 00 0.00 ATOM 988 2HE LYS+ 178-16.986-0.402 0.803 1.00 0.00 ATOM 989 QE LYS+ 178-16.295-0.259 0.273 1.00 0.00 ATOM 990 NZ LYS+ 178-15.573-1.963 0.757 1.00 0.00 ATOM 991 1HZ LYS+ 178-16.424-2.527 0.938 1.00 0.00 ATOM 992 2HZ LYS+ 178-14.880-2.148 1.515 1.00 0.00 ATOM 993 3HZ LYS+ 178-15.158-2.271-0.161 1.00 0.00 ATOM 994 QZ LYS+ 178-15.487-2.315 0.764 1.00 0.00 ATOM 995 C LYS+ 178-12.401 3.734 2.319 1.00 0.00 ATOM 996 O LYS+ 178-12.550 4.896 2.692 1.00 0.00 ATOM 997 N PHE 179-11.345 3.318 1.647 1.00 0.00 ATOM 998 H PHE 179-11.287 2.375 1.381 1.00 0.00 ATOM 999 CA PHE 179-10.259 4.214 1.302 1.00 0.00 ATOM 1000 HA PHE 179-10.558 5.219 1.558 1.00 0.00 ATOM 1001 CB PHE 179-9.000 3.851 2.087 1.00 0.00 ATOM 1002 1HB PHE 179-8.287 4.637 1.967 1.00 0.00 ATOM 1003 2HB PHE 179-8.580 2.942 1.685 1.00 0.00 ATOM 1004 QB PHE 179-8. 433 3.789 1.826 1.00 0.00 ATOM 1005 QD PHE 179-9.260 3.629 3.723 1.00 0.00 ATOM 1006 QE PHE 179-9.667 3.317 6.129 1. 00 0.00 ATOM 1007 QR PHE 179-9. 545 3.410 5.408 1.00 0.00 ATOM 1008 CG PHE 179-9.234 3.652 3.560 1.00 0.00 ATOM 1009 CD1 PHE 179-9.659 2.426 4.052 1.00 0.00 ATOM 1010 1HD PHE 179-9.813 1.604 3.368 1.00 0.00

ATOM 1011 CE1 PHE 179-9.887 2.249 5.402 1.00 0.00 ATOM 1012 1HE PHE 179-10.222 1.290 5.773 1.00 0.00 ATOM 1013 CZ PHE 179-9.690 3.297 6.279 1.00 0.00 ATOM 1014 HZ PHE 179-9.871 3.160 7.335 1.00 0.00 ATOM 1015 CE2 PHE 179-9. 265 4.522 5.802 1.00 0.00 ATOM 1016 2HE PHE 179-9.112 5.344 6.486 1.00 0.00 ATOM 1017 CD2 PHE 179-9.041 4.695 4.450 1.00 0.00 ATOM 1018 2HD PHE 179-8.708 5.654 4.079 1.00 0.00 ATOM 1019 C PHE 179-9.958 4.148-0.178 1.00 0.00 ATOM 1020 O PHE 179-10.616 3.423-0.922 1.00 0.00 ATOM 1021 N ARG+ 180-8.955 4.902-0.592 1.00 0.00 ATOM 1022 H ARG+ 180-8.476 5.457 0.064 1.00 0.00 ATOM 1023 CA ARG+ 180-8.542 4.938-1.988 1.00 0.00 ATOM 1024 HA ARG+ 180-8.972 4.081-2.487 1.00 0.00 ATOM 1025 CB ARG+ 180-9.050 6.217-2.663 1.00 0.00 ATOM 1026 1HB ARG+ 180-8.844 6.153-3.720 1.00 0.00 ATOM 1027 2HB ARG+ 180-8.513 7.060-2.258 1.00 0.00 ATOM 1028 QB ARG+ 180-8.678 6.606-2.989 1.00 0.00 ATOM 1029 CG ARG+ 180-10.538 6.464-2.477 1.00 0.00 ATOM 1030 1HG ARG+ 180-10.731 6. 650-1.429 1.00 0.00 ATOM 1031 2HG ARG+ 180-11. 080 5.584-2.793 1.00 0.00 ATOM 1032 QG ARG+ 180-10.905 6.117-2.111 1.00 0.00 ATOM 1033 CD ARG+ 180-11.017 7.656-3.287 1.00 0. 00 ATOM 1034 1HD ARG+ 180-10. 174 8.301-3.487 1.00 0.00 ATOM 1035 2HD ARG+ 180-11. 753 8.194-2.709 1.00 0.00 ATOM 1036 QD ARG+ 180-10.963 8.247-3.098 1.00 0.00 ATOM 1037 NE ARG+ 180-11. 614 7.244-4.557 1.00 0.00 ATOM 1038 HE ARG+ 180-11. 200 6.481-5.024 1.00 0.00 ATOM 1039 CZ ARG+ 180-12.672 7.837-5.109 1.00 0.00 ATOM 1040 NH1 ARG+ 180-13.248 8.868-4.498 1.00 0.00 ATOM 1041 1HH1 ARG+ 180-12.888 9.198-3.625 1.00 0.00 ATOM 1042 2HH1 ARG+ 180-14.044 9.316-4.907 1.00 0.00 ATOM 1043 QH1 ARG+ 180-13.466 9.257-4.266 1.00 0.00 ATOM 1044 NH2 ARG+ 180-13.149 7.401-6.269 1.00 0.00 ATOM 1045 1HH2 ARG+ 180-12.711 6.625-6.733 1.00 0.00 ATOM 1046 2HH2 ARG+ 180-13.940 7.844-6.688 1.00 0.00 ATOM 1047 QH2 ARG+ 180-13.325 7.234-6.711 1.00 0.00 ATOM 1048 C ARG+ 180-7.022 4.874-2.110 1.00 0.00 ATOM 1049 O ARG+ 180-6.491 4.540-3.160 1.00 0.00 ATOM 1050 N GLY 181-6.319 5.208-1.042 1.00 0.00 ATOM 1051 H GLY 181-6.780 5.475-0.216 1.00 0.00 ATOM 1052 CA GLY 181-4.871 5.196-1.098 1.00 0.00 ATOM 1053 1HA GLY 181-4.501 6.148-0.745 1.00 0.00 ATOM 1054 2HA GLY 181-4.568 5.067-2.126 1.00 0.00 ATOM 1055 QA GLY 181-4.534 5.607-1.436 1.00 0.00 ATOM 1056 C GLY 181-4.246 4.097-0.274 1.00 0.00 ATOM 1057 O GLY 181-4.835 3.627 0.697 1.00 0.00 ATOM 1058 N VAL 182-3.042 3.698-0.664 1.00 0.00 ATOM 1059 H VAL 182-2.633 4.127-1.442 1.00 0.00 ATOM 1060 CA VAL 182-2.299 2.654 0.029 1.00 0.00 ATOM 1061 HA VAL 182-2.649 2.611 1.053 1.00 0.00 ATOM 1062 CB VAL 182-2.488 1.259-0.623 1.00 0.00 ATOM 1063 HB VAL 182-1.681 1.109-1.327 1.00 0.00 ATOM 1064 QG1 VAL 182-2.381-0.096 0. 673 1.00 0.00 ATOM 1065 QG2 VAL 182-4.114 1.135-1.566 1.00 0.00 ATOM 1066 CG1 VAL 182-2.402 0.164 0.425 1.00 0. 00 ATOM 1067 1HG1 VAL 182-3.254-0.493 0.330 1.00 0.00 ATOM 1068 2HG1 VAL 182-2.397 0.607 1.410 1.00 0.00 ATOM 1069 3HG1 VAL 182-1.494-0.403 0.279 1.00 0. 00 ATOM 1070 CG2 VAL 182-3.804 1.159-1.385 1.00 0.00 ATOM 1071 1HG2 VAL 182-4.099 0.123-1.458 1.00 0.00 ATOM 1072 2HG2 VAL 182-3.677 1.567-2.377 1.00 0.00 ATOM 1073 3HG2 VAL 182-4.567 1.715-0.861 1.00 0.00 ATOM 1074 QQG VAL 182-3.248 0.519-0.446 1.00 0.00 ATOM 1075 C VAL 182-0.806 2.985 0.023 1.00 0.00 ATOM 1076 O VAL 182-0.227 3.235-1.033 1.00 0.00 ATOM 1077 N GLU 183-0.191 2.977 1.199 1.00 0.00 ATOM 1078 H GLU 183-0.711 2.765 2.008 1.00 0.00 ATOM 1079 CA GLU 183 1.236 3.262 1.331 1.00 0.00 ATOM 1080 HA GLU 183 1.667 3.286 0.338 1.00 0.00 ATOM 1081 CB GLU 183 1.453 4.616 2.011 1. 00 0.00 ATOM 1082 1HB GLU 183 1.527 5.380 1.250 1.00 0.00

ATOM 1083 2HB GLU 183 2.382 4.583 2.561 1.00 0.00 ATOM 1084 QB GLU 183 1.955 4.981 1.905 1.00 0.00 ATOM 1085 CG GLU 183 0.349 5.014 2.976 1.00 0.00 ATOM 1086 1HG GLU 183 0.343 4.321 3.804 1.00 0.00 ATOM 1087 2HG GLU 183-0.599 4.970 2.461 1.00 0.00 ATOM 1088 QG GLU 183-0.128 4.645 3.132 1.00 0.00 ATOM 1089 CD GLU 183 0.538 6.412 3.517 1.00 0.00 ATOM 1090 OE1 GLU 183 1.661 6.946 3.394 1.00 0.00 ATOM 1091 OE2 GLU 183-0.435 6.978 4.051 1.00 0.00 ATOM 1092 C GLU 183 1.904 2.154 2.135 1.00 0.00 ATOM 1093 O GLU 183 1.839 2.135 3.358 1.00 0.00 ATOM 1094 N PHE 184 2.501 1.202 1.444 1.00 0.00 ATOM 1095 H PHE 184 2.493 1.245 0.470 1.00 0.00 ATOM 1096 CA PHE 184 3.119 0.061 2.103 1.00 0.00 ATOM 1097 HA PHE 184 2.959 0.174 3.163 1.00 0.00 ATOM 1098 CB PHE 184 2.445-1.236 1.642 1.00 0.00 ATOM 1099 1HB PHE 184 1.544-1.392 2.218 1.00 0.00 ATOM 1100 2HB PHE 184 3.119-2.063 1.821 1.00 0.00 ATOM 1101 QB PHE 184 2.332-1.728 2.019 1.00 0.00 ATOM 1102 QD PHE 184 2.031-1.255 0.008 1.00 0.00 ATOM 1103 QE PHE 184 1.414-1.322-2.369 1.00 0.00 ATOM 1104 QR PHE 184 1.598-1.303-1.656 1.00 0.00 ATOM 1105 CG PHE 184 2.074-1.254 0.176 1.00 0.00 ATOM 1106 CD1 PHE 184 1.029-0.479-0.309 1.00 0.00 ATOM 1107 1HD PHE 184 0.483 0.159 0.371 1.00 0.00 ATOM 1108 CE1 PHE 184 0.679-0.516-1.645 1.00 0.00 ATOM 1109 1HE PHE 184-0.136 0.093-2.008 1.00 0.00 ATOM 1110 CZ PHE 184 1.375-1.328-2.515 1.00 0.00 ATOM 1111 HZ PHE 184 1.100-1.364-3.558 1.00 0.00 ATOM 1112 CE2 PHE 184 2.417-2.100-2.050 1.00 0.00 ATOM 1113 2HE PHE 184 2.963-2.736-2.730 1.00 0.00 ATOM 1114 CD2 PHE 184 2.760-2.062-0.713 1.00 0.00 ATOM 1115 2HD PHE 184 3.578-2.668-0.354 1.00 0.00 ATOM 1116 C PHE 184 4. 613-0.038 1.846 1.00 0.00 ATOM 1117 O PHE 184 5.081 0.174 0.734 1.00 0.00 ATOM 1118 N VAL 185 5. 350-0.394 2.886 1.00 0.00 ATOM 1119 H VAL 185 4. 909-0.567 3.745 1.00 0.00 ATOM 1120 CA VAL 185 6.787-0.559 2.790 1.00 0.00 ATOM 1121 HA VAL 185 7.110-0.179 1.830 1.00 0.00 ATOM 1122 CB VAL 185 7. 522 0.218 3.908 1.00 0.00 ATOM 1123 HB VAL 185 7.678-0.454 4.745 1.00 0.00 ATOM 1124 QG1 VAL 185 9. 196 0.819 3.318 1.00 0.00 ATOM 1125 QG2 VAL 185 6. 498 1.673 4.513 1.00 0.00 ATOM 1126 CG1 VAL 185 8.875 0.703 3.430 1.00 0.00 ATOM 1127 1HG1 VAL 185 9.629 0.431 4.154 1.00 0.00 ATOM 1128 2HG1 VAL 185 8.852 1.778 3.322 1.00 0.00 ATOM 1129 3HG1 VAL 185 9.107 0.249 2.479 1.00 0.00 ATOM 1130 CG2 VAL 185 6.694 1.394 4.396 1.00 0.00 ATOM 1131 1HG2 VAL 185 6.939 2.273 3.819 1.00 0.00 ATOM 1132 2HG2 VAL 185 6.910 1.577 5.440 1.00 0.00 ATOM 1133 3HG2 VAL 185 5.644 1.169 4.282 1.00 0.00 ATOM 1134 QQG VAL 185 7.847 1.246 3.916 1. 00 0. 00 ATOM 1135 C VAL 185 7. 130-2.047 2.877 1.00 0.00 ATOM 1136 O VAL 185 7.041-2.655 3.942 1.00 0.00 ATOM 1137 N CYS 186 7.497-2.643 1.750 1.00 0.00 ATOM 1138 H CYS 186 7.534-2.119 0.918 1.00 0.00 ATOM 1139 CA CYS 186 7.828-4.063 1.720 1. 00 0. 00 ATOM 1140 HA CYS 186 7.608-4.467 2.700 1.00 0.00 ATOM 1141 CB CYS 186 6.961-4.799 0.687 1.00 0.00 ATOM 1142 1HB CYS 186 5.938-4.806 1.034 1.00 0.00 ATOM 1143 2HB CYS 186 7. 309-5.817 0.605 1. 00 0. 00 ATOM 1144 QB CYS 186 6.624-5.312 0.819 1.00 0.00 ATOM 1145 SG CYS 186 6.969-4.088-0.989 1. 00 0. 00 ATOM 1146 C CYS 186 9.315-4.271 1.433 1. 00 0. 00 ATOM 1147 0 CYS 186 9.849-3.720 0.477 1. 00 0. 00 ATOM 1148 N CYS 187 9.985-5.066 2.261 1. 00 0. 00 ATOM 1149 H CYS 187 9.512-5.487 3.012 1. 00 0. 00 ATOM 1150 CA CYS 187 11.420-5.323 2.076 1. 00 0. 00 ATOM 1151 HA CYS 187 11.841-4.475 1.559 1.00 0.00 ATOM 1152 CB CYS 187 12.131-5.485 3.425 1.00 0.00 ATOM 1153 1HB CYS 187 12.942-6.192 3.311 1.00 0. 00 ATOM 1154 2HB CYS 187 11.430-5.867 4.152 1.00 0.00

ATOM 1155 QB CYS 187 12.186-6.030 3.731 1.00 0.00 ATOM 1156 SG CYS 187 12.832-3.942 4.091 1.00 0.00 ATOM 1157 C CYS 187 11.650-6.566 1.238 1.00 0.00 ATOM 1158 0 CYS 187 10.792-7.439 1.184 1.00 0.00 ATOM 1159 N PRO 188 12.812-6.654 0.564 1.00 0.00 ATOM 1160 CD PRO 188 13.887-5.640 0.569 1.00 0.00 ATOM 1161 CA PRO 188 13.145-7.802-0.285 1.00 0.00 ATOM 1162 HA PRO 188 12.404-7.944-1.059 1.00 0.00 ATOM 1163 CB PRO 188 14.484-7.418-0.924 1.00 0.00 ATOM 1164 1HB PRO 188 14.314-7.050-1.924 1.00 0.00 ATOM 1165 2HB PRO 188 15.125-8.288-0.960 1.00 0.00 ATOM 1166 QB PRO 188 14.720-7.669-1.442 1.00 0.00 ATOM 1167 CG PRO 188 15.056-6.359-0.042 1.00 0.00 ATOM 1168 1HG PRO. 188 15.651-5.675-0.630 1.00 0.00 ATOM 1169 2HG PRO 188 15.660-6.814 0.730 1.00 0.00 ATOM 1170 QG PRO 188 15.656-6.245 0.050 1.00 0.00 ATOM 1171 1HD PRO 188 13.614-4.783-0.030 1.00 0.00 ATOM 1172 2HD PRO 188 14.122-5.334 1.579 1.00 0.00 ATOM 1173 QD PRO 188 13.868-5.059 0.774 1.00 0.00 ATOM 1174 C PRO 188 13.285-9.099 0.508 1.00 0.00 ATOM 1175 O PRO 188 14.013-9.157 1.503 1.00 0.00 ATOM 1176 N LEU 189 12.585-10.126 0.049 1.00 0.00 ATOM 1177 H LEU 189 12.031-10.002-0.751 1.00 0.00 ATOM 1178 CA LEU 189 12.614-11.434 0.679 1.00 0.00 ATOM 1179 HA LEU 189 13.372-11.421 1.447 1.00 0.00 ATOM 1180 CB LEU 189 11.257-11.755 1.309 1.00 0.00 ATOM 1181 1HB LEU 189 10.530-11.839 0.516 1.00 0.00 ATOM 1182 2HB LEU 189 10.977-10.931 1.949 1.00 0.00 ATOM 1183 QB LEU 189 10.754-11.385 1.232 1.00 0.00 ATOM 1184 CG LEU 189 11.215-13.043 2.134 1.00 0.00 ATOM 1185 HG LEU 189 11.796-13.802 1.629 1.00 0.00 ATOM 1186 QD1 LEU 189 11.971-12.766 3.831 1.00 0.00 ATOM 1187 QD2 LEU 189 9.450-13.665 2.291 1.00 0.00 ATOM 1188 CD1 LEU 189 11.826-12.819 3.507 1.00 0.00 ATOM 1189 1HD1 LEU 189 11.334-11.987 3.988 1.00 0.00 ATOM 1190 2HD1 LEU 189 12.879-12.603 3.400 1.00 0.00 ATOM 1191 3HD1 LEU 189 11.699-13.708 4.106 1.00 0.00 ATOM 1192 CD2 LEU 189 9.787-13.546 2.262 1.00 0.00 ATOM 1193 1HD2 LEU 189 9.195-12.814 2.790 1.00 0.00 ATOM 1194 2HD2 LEU 189 9.782-14.477 2.808 1.00 0.00 ATOM 1195 3HD2 LEU 189 9.372-13.704 1.277 1.00 0.00 ATOM 1196 QQD LEU 189 10.711-13.216 3.061 1.00 0.00 ATOM 1197 C LEU 189 12.971-12.497-0.355 1.00 0.00 ATOM 1198 OT1 LEU 189 13.573-13.522 0.028 1.00 0.00 ATOM 1199 OT2 LEU 189 12.646-12.292-1.545 1.00 0.00 TER ENDMDL END