Title:
METHOD FOR SCREENING LOW BODY WEIGHT-INDUCING AGENT, LOW BODY WEIGHT-INDUCING AGENT, AND LOW BODY WEIGHT ANIMAL MODEL
Document Type and Number:
WIPO Patent Application WO/2018/159817
Kind Code:
A1
Abstract:
Provided is a low body weight-inducing agent which comprises a compound capable of inhibiting the expression of the function of GPRC5C gene or GPRC5C protein.
Inventors:
ISHIMARU YOSHIRO (JP)
ABE KEIKO (JP)
ASAKURA TOMIKO (JP)
TANISHITA MICHIHIRO (JP)
TANABE SOICHI (JP)
ABE KEIKO (JP)
ASAKURA TOMIKO (JP)
TANISHITA MICHIHIRO (JP)
TANABE SOICHI (JP)
Application Number:
PCT/JP2018/008036
Publication Date:
September 07, 2018
Filing Date:
March 02, 2018
Export Citation:
Assignee:
NISSIN FOODS HOLDINGS CO LTD (JP)
International Classes:
A61K45/00; A01K67/027; A61P3/04; G01N33/15; C12N15/09; C12Q1/68
Domestic Patent References:
| WO2007119623A1 | 2007-10-25 |
Other References:
SANO, T. ET AL.: "Comparative characterization of GPRC5B and GPRC5C Lacz knock in mice; behavioral abnormalities in GPRC5B-deficient mice", BIOCHEM BIOPHYS RES COMMUN, vol. 412, no. 3, 5 August 2011 (2011-08-05), pages 460 - 5, XP028281758, ISSN: 0006-291X, Retrieved from the Internet
RAJKUMAR, P. ET AL.: "A Novel GPRC in the Renal Proximal Tubules, Gprc5c, Is Involved in Systemic pH Regulation", FASEB J, vol. 30, no. 1 suppl., 1 April 2016 (2016-04-01), XP055543577, ISSN: 1530-6860
RAJKUMAR, P. ET AL.: "A Novel GPRC in the Renal Proximal Tubules, Gprc5c, Is Involved in Systemic pH Regulation", FASEB J, vol. 30, no. 1 suppl., 1 April 2016 (2016-04-01), XP055543577, ISSN: 1530-6860
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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