Title:
METHOD FOR SCREENING MATERIAL REVERSING FINE DUST-INDUCED RESTRICTION OF KERATINOCYTE DIFFERENTIATION AND COMPOSITION FOR REVERSING FINE DUST-INDUCED RESTRICTION OF KERATINOCYTE DIFFERENTIATION
Document Type and Number:
WIPO Patent Application WO/2019/199089
Kind Code:
A1
Abstract:
The present invention relates to a method for screening a material reversing fine dust-induced restriction of keratinocyte differentiation, the method comprising a step of identifying a relative degree of formation of primary cilia in keratinocytes. According to an aspect of the present invention, a material reversing fine dust-induced restriction of keratinocyte differentiation can be effectively screened and excavated, thereby allowing a plan to develop a business related to skin health associated with fine dust.
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Inventors:
CHOI HYUN JUNG (KR)
KIM HYOUNG JUNE (KR)
LEE TAE RYONG (KR)
CHO DONG HYUNG (KR)
JO DOO SIN (KR)
KIM HYOUNG JUNE (KR)
LEE TAE RYONG (KR)
CHO DONG HYUNG (KR)
JO DOO SIN (KR)
Application Number:
PCT/KR2019/004382
Publication Date:
October 17, 2019
Filing Date:
April 11, 2019
Export Citation:
Assignee:
AMOREPACIFIC CORP (KR)
UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR)
UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR)
International Classes:
G01N33/50; A23L33/10; A61K8/49; A61Q19/00; G01N33/68
Foreign References:
| KR20160119703A | 2016-10-14 | |||
| KR20180023362A | 2018-03-07 | |||
| KR20180022416A | 2018-03-06 | |||
| KR20170058606A | 2017-05-29 | |||
| KR20180032953A | 2018-04-02 |
Other References:
KANG, JIN-HEE ET AL.: "Particulate Matter and Skin", KOREAN J. FAM. PRACT., vol. 4, 2014, pages 116 - 121
KIM, JOON: "Functional genomic screen for modulators of ciliogenesis and cilium length", NATURE, 2010, pages 1048 - 1052, XP055182068
BATTLE, CHRISTOPHER: "Intracellular and extracellular forces drive primary cilia movement", PNAS, 2015, pages 1410 - 1415, XP055645067
BAE, JI-EUN: "Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin kera- tinocytes", SCIENTIFIC REPORTS, vol. 3994, 8 March 2019 (2019-03-08), pages 1 - 9, XP055645070
KIM, JOON: "Functional genomic screen for modulators of ciliogenesis and cilium length", NATURE, 2010, pages 1048 - 1052, XP055182068
BATTLE, CHRISTOPHER: "Intracellular and extracellular forces drive primary cilia movement", PNAS, 2015, pages 1410 - 1415, XP055645067
BAE, JI-EUN: "Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin kera- tinocytes", SCIENTIFIC REPORTS, vol. 3994, 8 March 2019 (2019-03-08), pages 1 - 9, XP055645070
Attorney, Agent or Firm:
KIM, Sun-young (KR)
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