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Title:
METHOD FOR SCREENING MITOCHONDRIAL ACTIVITY ENHANCER
Document Type and Number:
WIPO Patent Application WO/2017/003124
Kind Code:
A1
Abstract:
The present invention relates to a method for screening a mitochondrial activity enhancer by using gypenoside-treated cells, to a composition, containing the gypenoside, for screening the mitochondrial activity enhancer, and to a kit comprising the composition. The method for screening a mitochondrial activity enhancer according to the present invention enables a preparation capable of substantially enhancing the mitochondrial activity to be efficiently discovered, and thus the method can be expected to be widely used in developing a therapeutic agent for diseases caused by mitochondrial activity inhibition.

Inventors:
KIM, Sun Chang (401 ho, 291 Daehak-ro,,Yuseong-gu, Daejeon, 34141, KR)
PARK, Chan Bae (107-402, 11 Giheung-ro 38beon-gil, Giheung-gu,,Yongin-si, Gyeonggi-do, 16975, KR)
LEE, Soon Jang (4209-1201, 62 Gwanggyomaeul-ro, Suji-gu,,Yongin-si, Gyeonggi-do, 16943, KR)
Application Number:
KR2016/006592
Publication Date:
January 05, 2017
Filing Date:
June 22, 2016
Export Citation:
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Assignee:
INTELLIGENT SYNTHETIC BIOLOGY CENTER (401 ho, 291 Daehak-ro,,Yuseong-gu, Daejeon, 34141, KR)
International Classes:
G01N33/50; C07J17/00
Domestic Patent References:
WO2000044931A22000-08-03
Foreign References:
KR20130064761A2013-06-18
KR20130069430A2013-06-26
KR20080085292A2008-09-24
Other References:
LI, LIN ET AL.: "Protective Effect of Gypenosides against Oxidative Stress in Phagocytes, Vascular Endothelial Cells and Liver Microsomes", CANCER BIOTHERAPY, vol. 8, no. 3, 1993, pages 263 - 272, XP055342337
See also references of EP 3182123A4
Attorney, Agent or Firm:
SON, Min (Hanol Intellectual Property&Law, 6th Floor 163, YangJaeCheon-ro,,Gangnam-gu, Seoul, 06302, KR)
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