Title:
METHOD FOR SCREENING SKIN ENDOGENOUS AGING TARGETS, ACTIVE MATERIAL FOR IMPROVING SKIN ENDOGENOUS AGING AND SCREENING METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2019/165963
Kind Code:
A1
Abstract:
Disclosed in the present invention are a method for screening skin endogenous aging targets, an active material for improving skin endogenous aging and a screening method therefor. A microRNA in the skin is used as a detection basis, and the microRNA is any one or a combination of two of hsa-miR-30c-2-3p and hsa-miR-125b-1-3p. The microRNA has the effect of inhibiting the expression of IGF1 gene and IGF1R gene, thereby affecting endogenous aging of the skin. The present invention provides a novel regulatory target for the development of cosmetic active ingredients that improve endogenous aging of the skin.
Inventors:
JIANG DANDAN (CN)
MORGAN DOS SANTOS (CN)
LI HUI (CN)
MORGAN DOS SANTOS (CN)
LI HUI (CN)
Application Number:
PCT/CN2019/076231
Publication Date:
September 06, 2019
Filing Date:
February 27, 2019
Export Citation:
Assignee:
JALA GROUP COMPANY (CN)
International Classes:
C12Q1/68; A61K36/00; A61P17/00
Foreign References:
| CN102625853A | 2012-08-01 | |||
| CN105232600A | 2016-01-13 | |||
| CN104622704A | 2015-05-20 |
Other References:
See also references of EP 3763822A4
Attorney, Agent or Firm:
SHANGHAI HUIYE LAW FIRM (CN)
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