Title:
METHOD FOR SCREENING SUBSTANCE HAVING HIGH AFFINITY FOR TARGET SUBSTANCE
Document Type and Number:
WIPO Patent Application WO/2018/143357
Kind Code:
A1
Abstract:
This method for screening a substance having a high affinity for a target substance includes: a step of preparing a measurement sample in which a sample containing a candidate substance is brought into contact with the target substance; a step in which the measurement sample is subjected to imaging mass spectrometry using matrix assisted laser desorption/ionization (MALDI) with the target substance as a matrix, to identify an ionized molecule; and a step of selecting the identified molecule as being a substance having high affinity for the target substance.
Inventors:
SETOU MITSUTOSHI (JP)
KONDO TAKESHI (JP)
KONDO TAKESHI (JP)
Application Number:
PCT/JP2018/003442
Publication Date:
August 09, 2018
Filing Date:
February 01, 2018
Export Citation:
Assignee:
NATIONAL UNIV CORPORATION HAMAMATSU UNIV SCHOOL OF MEDICINE (JP)
International Classes:
G01N33/15; G01N27/62
Foreign References:
| JP2016080531A | 2016-05-16 | |||
| JP2007170870A | 2007-07-05 | |||
| JP2016121968A | 2016-07-07 | |||
| JP2016511402A | 2016-04-14 | |||
| JP2014206389A | 2014-10-30 | |||
| JP2008111841A | 2008-05-15 | |||
| JP2003248001A | 2003-09-05 | |||
| JP2015155884A | 2015-08-27 | |||
| JP2008542784A | 2008-11-27 |
Attorney, Agent or Firm:
NIIYAMA Yuichi et al. (JP)
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