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Patent Searching and Data


Title:
METHOD FOR SELECTION OF CHEMOTHERAPEUTIC AGENTS FOR ADENOCARCINOMA CANCER
Document Type and Number:
WIPO Patent Application WO/2013/019945
Kind Code:
A3
Abstract:
The subject invention relates to determining the presence and level of hENT1 expression in tumor tissue that is appropriate for gemcitabine therapy, and more importantly, the level of hENT1 expression that signifies that treatment with a gemcitabine derivative is a more appropriate strategy.

Inventors:
ISAACSON, Jeffrey, Dean (3201 West Torreys Peak Drive, Superior, Colorado, 80027, US)
RAPONI, Mical (169 Belvedere Street, San Francisco, California, 94117, US)
RANGER-MOORE, James (1531 E. Waverly Street, Tucson, Arizona, 85719, US)
POWELL, Eric, L. (100 Sportfisher Drive, #301Oceanside, California, 92054, US)
Application Number:
US2012/049320
Publication Date:
May 08, 2014
Filing Date:
August 02, 2012
Export Citation:
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Assignee:
ISAACSON, Jeffrey, Dean (3201 West Torreys Peak Drive, Superior, Colorado, 80027, US)
RAPONI, Mical (169 Belvedere Street, San Francisco, California, 94117, US)
RANGER-MOORE, James (1531 E. Waverly Street, Tucson, Arizona, 85719, US)
POWELL, Eric, L. (100 Sportfisher Drive, #301Oceanside, California, 92054, US)
CLOVIS ONCOLOGY, INC.. (2525 28th Street, Suite 100Boulder, Colorado, 80301, US)
VENTANA MEDICAL SYSTEMS, INC. (1910 E. Innovation Park Drive, Tucson, Arizona, 85755, US)
International Classes:
A01N43/04; A61K31/70; C07H19/00
Foreign References:
US20020042391A1
US20100016254A1
Other References:
FARRELL ET AL.: "Human equilibrative nucleoside transporter 1 levels predict response to gemcitabine in patients with pancreatic cancer", GASTROENTEROLOGY, vol. 136, no. 1, 1 January 2009 (2009-01-01), pages 187 - 195, XP025999654
See also references of EP 2739290A2
Attorney, Agent or Firm:
VENTANA MEDICAL SYSTEMS, INC. et al. (Attn: Legal Department, 1910 East Innovation Park DriveTucson, AZ, 85755, US)
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