Title:
METHOD FOR SYNTHESIS OF ELIGLUSTAT AND INTERMEDIATE COMPOUNDS THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/171173
Kind Code:
A1
Abstract:
The present invention relates to a method for synthesis of Eliglustat and intermediate compounds thereof. Specifically, the present invention relates to the field of synthesis of organic compounds, to a method for synthesis of Eliglustat and pharmaceutically acceptable salts thereof, and further to intermediate compounds used in the method and a preparation method for the intermediate compounds. Compared with an existing synthesis method, the method for synthesis of Eliglustat of the present invention uses novel synthetic intermediates and synthesis steps, features ease of operation, high yield, good purity of intermediates and target products, etc., and facilitates industrial production.
Inventors:
LIU YU (CN)
YU GUANGNENG (CN)
ZHENG ZHIGUO (CN)
YU GUANGNENG (CN)
ZHENG ZHIGUO (CN)
Application Number:
PCT/CN2017/106348
Publication Date:
September 27, 2018
Filing Date:
October 16, 2017
Export Citation:
Assignee:
ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D319/18; C07D413/06; C07F7/18
Domestic Patent References:
| WO2017068496A1 | 2017-04-27 |
Foreign References:
| CN106967042A | 2017-07-21 | |||
| CN105646442A | 2016-06-08 | |||
| CN106349210A | 2017-01-25 | |||
| CN104557851A | 2015-04-29 | |||
| US7196205B2 | 2007-03-27 | |||
| US7196205B2 | 2007-03-27 | |||
| CN104557851A | 2015-04-29 | |||
| CN105646442A | 2016-06-08 |
Other References:
See also references of EP 3611171A4
Attorney, Agent or Firm:
ZHONGZI LAW OFFICE (CN)
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