Title:
METHOD FOR SYNTHESIS OF HYDROGENOFLUOROMETHYLENESULPHONYL RADICAL DERIVATIVES
Document Type and Number:
WIPO Patent Application WO2004002951
Kind Code:
A3
Abstract:
The invention concerns a method for synthesis of hydrogenofluoromethylenesulphonyl radical derivatives, comprising: a) a step which consists in condensing a thiolate (that is a monoalkyl sulphide salt) with a compound having a sp<3> hybridized carbon bearing a hydrogen, a fluorine, a heavy halogen selected among chlorine, bromine and iodine and an electron-attracting group selected among fluorine and those whereof the sigma p is not less than 0.2, advantageously than 0.4; b) a step which consists in oxidizing the compound obtained in step a). The invention is applicable to the synthesis of various compounds having a suphinyl or sulphonyl group.
Inventors:
SAINT-JALMES LAURENT (FR)
Application Number:
PCT/FR2003/001940
Publication Date:
April 15, 2004
Filing Date:
June 24, 2003
Export Citation:
Assignee:
RHODIA CHIMIE SA (FR)
SAINT-JALMES LAURENT (FR)
SAINT-JALMES LAURENT (FR)
International Classes:
C07C303/16; C07C303/22; C07C309/06; C07C309/80; C07C319/14; C07C323/03; (IPC1-7): C07C319/14; C07C323/03; C07C303/16; C07C309/80
Other References:
G.G.I. MOORE, ET AL.: "Fluoroalkanesulphonyl chlorides", JOURNAL OF ORGANIC CHEMISTRY, vol. 44, no. 10, 11 May 1979 (1979-05-11), American Chemical Society, Washington, DC, US, pages 1708 - 1711, XP002952300, ISSN: 0022-3263
B.R. LANGLOIS: "Improvement of the synthesis of aryl difluoromethyl ethers and thioethers by using a solid-liquid phase-transfer technique", JOURNAL OF FLUORINE CHEMISTRY, vol. 41, no. 2, November 1988 (1988-11-01), Elsevier Sequoia, Lausanne, CH, pages 247 - 261, XP002232989, ISSN: 0022-1139
R. FELDHOFF, ET AL.: "Darstellung und Eigenschaften Trifluomethyl- und Trifluomethylchalkogenyl-substituierter Adamantane", JOURNAL OF FLUORINE CHEMISTRY, vol. 67, no. 3, June 1994 (1994-06-01), Elsevier Sequoia, Lausanne, CH, pages 245 - 251, XP002232990, ISSN: 0022-1139
B.R. LANGLOIS: "Improvement of the synthesis of aryl difluoromethyl ethers and thioethers by using a solid-liquid phase-transfer technique", JOURNAL OF FLUORINE CHEMISTRY, vol. 41, no. 2, November 1988 (1988-11-01), Elsevier Sequoia, Lausanne, CH, pages 247 - 261, XP002232989, ISSN: 0022-1139
R. FELDHOFF, ET AL.: "Darstellung und Eigenschaften Trifluomethyl- und Trifluomethylchalkogenyl-substituierter Adamantane", JOURNAL OF FLUORINE CHEMISTRY, vol. 67, no. 3, June 1994 (1994-06-01), Elsevier Sequoia, Lausanne, CH, pages 245 - 251, XP002232990, ISSN: 0022-1139
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